MECP2

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Results for "MECP2": 1 gene, 35 gene sets

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MECP2 Gene methyl CpG binding protein 2 DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of cognitive disability in females. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
mecp2 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term mecp2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
MECP2 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for MECP2 from the Pathway Commons Protein-Protein Interactions dataset.
MECP2 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the MECP2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
MECP2 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the MECP2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
PU.1-Sin3A-Hdac-MeCP2 complex Gene Set From CORUM Protein Complexes proteins in the PU.1-Sin3A-Hdac-MeCP2 complex protein complex from the CORUM Protein Complexes dataset.
MeCP2-SIN3A-HDAC complex Gene Set From CORUM Protein Complexes proteins in the MeCP2-SIN3A-HDAC complex protein complex from the CORUM Protein Complexes dataset.
Smarcb1/Ini1-Smarca2-Mecp2 complex Gene Set From CORUM Protein Complexes proteins in the Smarcb1/Ini1-Smarca2-Mecp2 complex protein complex from the CORUM Protein Complexes dataset.
Hdac1-Mecp2-Rcor1-Sin3a complex Gene Set From CORUM Protein Complexes proteins in the Hdac1-Mecp2-Rcor1-Sin3a complex protein complex from the CORUM Protein Complexes dataset.
SWI/SNF chromatin-remodeling complex (Mecp2, Smarc) Gene Set From CORUM Protein Complexes proteins in the SWI/SNF chromatin-remodeling complex (Mecp2, Smarc) protein complex from the CORUM Protein Complexes dataset.
SMARCA2/BRM-BAF57-MECP2 complex Gene Set From CORUM Protein Complexes proteins in the SMARCA2/BRM-BAF57-MECP2 complex protein complex from the CORUM Protein Complexes dataset.
Encephalopathy, Neonatal Severe, Due To Mecp2 Mutations Gene Set From CTD Gene-Disease Associations genes/proteins associated with the disease Encephalopathy, Neonatal Severe, Due To Mecp2 Mutations from the curated CTD Gene-Disease Associations dataset.
Methyl-CpG binding protein MeCP2 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Methyl-CpG binding protein MeCP2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
MECP2 and associated Rett syndrome Gene Set From WikiPathways Pathways 2024 proteins participating in the MECP2 and associated Rett syndrome pathway from the WikiPathways Pathways 2024 dataset.
Loss of MECP2 binding ability to 5hmC-DNA Gene Set From Reactome Pathways 2024 proteins participating in the Loss of MECP2 binding ability to 5hmC-DNA pathway from the Reactome Pathways 2024 dataset.
Loss of MECP2 binding ability to 5mC-DNA Gene Set From Reactome Pathways 2024 proteins participating in the Loss of MECP2 binding ability to 5mC-DNA pathway from the Reactome Pathways 2024 dataset.
Loss of MECP2 binding ability to the NCoR/SMRT complex Gene Set From Reactome Pathways 2024 proteins participating in the Loss of MECP2 binding ability to the NCoR/SMRT complex pathway from the Reactome Pathways 2024 dataset.
Loss of function of MECP2 in Rett syndrome Gene Set From Reactome Pathways 2024 proteins participating in the Loss of function of MECP2 in Rett syndrome pathway from the Reactome Pathways 2024 dataset.
Loss of phosphorylation of MECP2 at T308 Gene Set From Reactome Pathways 2024 proteins participating in the Loss of phosphorylation of MECP2 at T308 pathway from the Reactome Pathways 2024 dataset.
MECP2 regulates neuronal receptors and channels Gene Set From Reactome Pathways 2024 proteins participating in the MECP2 regulates neuronal receptors and channels pathway from the Reactome Pathways 2024 dataset.
MECP2 regulates transcription factors Gene Set From Reactome Pathways 2024 proteins participating in the MECP2 regulates transcription factors pathway from the Reactome Pathways 2024 dataset.
MECP2 regulates transcription of genes involved in GABA signaling Gene Set From Reactome Pathways 2024 proteins participating in the MECP2 regulates transcription of genes involved in GABA signaling pathway from the Reactome Pathways 2024 dataset.
MECP2 regulates transcription of neuronal ligands Gene Set From Reactome Pathways 2024 proteins participating in the MECP2 regulates transcription of neuronal ligands pathway from the Reactome Pathways 2024 dataset.
Regulation of MECP2 expression and activity Gene Set From Reactome Pathways 2024 proteins participating in the Regulation of MECP2 expression and activity pathway from the Reactome Pathways 2024 dataset.
Transcriptional Regulation by MECP2 Gene Set From Reactome Pathways 2024 proteins participating in the Transcriptional Regulation by MECP2 pathway from the Reactome Pathways 2024 dataset.
Severe congenital encephalopathy due to MECP2 mutation Gene Set From DISEASES Curated Gene-Disease Association Evidence Scores 2025 genes involed in the disease Severe congenital encephalopathy due to MECP2 mutation from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
Severe congenital encephalopathy due to MECP2 mutation Gene Set From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease Severe congenital encephalopathy due to MECP2 mutation in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
PMC6815046-13073_2019_678_MOESM3_ESM.xlsx-MECP2-Unnamed_0_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC6815046-13073_2019_678_MOESM3_ESM.xlsx-MECP2-Unnamed_0_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.
PMC6815046-13073_2019_678_MOESM2_ESM.xlsx-MECP2-Unnamed_0_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC6815046-13073_2019_678_MOESM2_ESM.xlsx-MECP2-Unnamed_0_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.
PMC6815046-13073_2019_678_MOESM4_ESM.xlsx-MECP2-Unnamed_0_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC6815046-13073_2019_678_MOESM4_ESM.xlsx-MECP2-Unnamed_0_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.
PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Non-metastasis_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Non-metastasis_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.
PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Unnamed_1_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Unnamed_1_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.
PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Metastasis_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Metastasis_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.
PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Unnamed_5_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Unnamed_5_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-fromNode_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-fromNode_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2 Gene Set From Rummagene Transcription Factor Associations 2026 target genes of the PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

Harmonizome 3.0

MECP2 Gene

mecp2 Gene Set

MECP2 Gene Set

MECP2 Gene Set

MECP2 Gene Set

PU.1-Sin3A-Hdac-MeCP2 complex Gene Set

MeCP2-SIN3A-HDAC complex Gene Set

Smarcb1/Ini1-Smarca2-Mecp2 complex Gene Set

Hdac1-Mecp2-Rcor1-Sin3a complex Gene Set

SWI/SNF chromatin-remodeling complex (Mecp2, Smarc) Gene Set

SMARCA2/BRM-BAF57-MECP2 complex Gene Set

Encephalopathy, Neonatal Severe, Due To Mecp2 Mutations Gene Set

Methyl-CpG binding protein MeCP2 Gene Set

MECP2 and associated Rett syndrome Gene Set

Loss of MECP2 binding ability to 5hmC-DNA Gene Set

Loss of MECP2 binding ability to 5mC-DNA Gene Set

Loss of MECP2 binding ability to the NCoR/SMRT complex Gene Set

Loss of function of MECP2 in Rett syndrome Gene Set

Loss of phosphorylation of MECP2 at T308 Gene Set

MECP2 regulates neuronal receptors and channels Gene Set

MECP2 regulates transcription factors Gene Set

MECP2 regulates transcription of genes involved in GABA signaling Gene Set

MECP2 regulates transcription of neuronal ligands Gene Set

Regulation of MECP2 expression and activity Gene Set

Transcriptional Regulation by MECP2 Gene Set

Severe congenital encephalopathy due to MECP2 mutation Gene Set

Severe congenital encephalopathy due to MECP2 mutation Gene Set

PMC6815046-13073_2019_678_MOESM3_ESM.xlsx-MECP2-Unnamed_0_MECP2 Gene Set

PMC6815046-13073_2019_678_MOESM2_ESM.xlsx-MECP2-Unnamed_0_MECP2 Gene Set

PMC6815046-13073_2019_678_MOESM4_ESM.xlsx-MECP2-Unnamed_0_MECP2 Gene Set

PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Non-metastasis_MECP2 Gene Set

PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Unnamed_1_MECP2 Gene Set

PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Metastasis_MECP2 Gene Set

PMC6292939-41598_2018_36168_MOESM8_ESM.xlsx-MECP2-Unnamed_5_MECP2 Gene Set

PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-fromNode_MECP2 Gene Set

PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2 Gene Set

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