Harmonizome 3.0

ras homolog family member A

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]

RHOA intronic transcript 1

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rhoa in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein RHOA from the curated Hub Proteins Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for RHOA from the Pathway Commons Protein-Protein Interactions dataset.

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term rhoa in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the RHOA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the RHOA gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the MRIP-MBS-RHOA complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the GNAQ-GEFT-RHOA complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the RHOA-IP3R-TRPC1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the MRIP-RHOA complex protein complex from the CORUM Protein Complexes dataset.

From PID Pathways

proteins participating in the RhoA signaling pathway pathway from the PID Pathways dataset.

From PID Pathways

proteins participating in the Regulation of RhoA activity pathway from the PID Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Axonal growth inhibition (RHOA activation) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2024

proteins participating in the Axonal growth inhibition (RHOA activation) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RHOA GTPase cycle pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SLIT2:ROBO1 increases RHOA activity pathway from the Reactome Pathways 2024 dataset.