TLR2

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Results for "TLR2": 1 gene, 17 gene sets

Name
TLR2 Gene toll-like receptor 2 The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
tlr2 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term tlr2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
TLR2 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for TLR2 from the Pathway Commons Protein-Protein Interactions dataset.
TLR2 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the TLR2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
toll-like receptor tlr1:tlr2 signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the toll-like receptor tlr1:tlr2 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
toll-like receptor tlr6:tlr2 signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the toll-like receptor tlr6:tlr2 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
Toll Like Receptor TLR6:TLR2 Cascade Gene Set From Reactome Pathways 2014 proteins participating in the Toll Like Receptor TLR6:TLR2 Cascade pathway from the Reactome Pathways dataset.
Toll Like Receptor TLR1:TLR2 Cascade Gene Set From Reactome Pathways 2014 proteins participating in the Toll Like Receptor TLR1:TLR2 Cascade pathway from the Reactome Pathways dataset.
Toll Like Receptor 2 (TLR2) Cascade Gene Set From Reactome Pathways 2014 proteins participating in the Toll Like Receptor 2 (TLR2) Cascade pathway from the Reactome Pathways dataset.
toll-like receptor TLR6:TLR2 signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the toll-like receptor TLR6:TLR2 signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
toll-like receptor TLR1:TLR2 signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the toll-like receptor TLR1:TLR2 signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
IRAK4 deficiency (TLR2/4) Gene Set From Reactome Pathways 2024 proteins participating in the IRAK4 deficiency (TLR2/4) pathway from the Reactome Pathways 2024 dataset.
MyD88 deficiency (TLR2/4) Gene Set From Reactome Pathways 2024 proteins participating in the MyD88 deficiency (TLR2/4) pathway from the Reactome Pathways 2024 dataset.
Toll Like Receptor 2 (TLR2) Cascade Gene Set From Reactome Pathways 2024 proteins participating in the Toll Like Receptor 2 (TLR2) Cascade pathway from the Reactome Pathways 2024 dataset.
Toll Like Receptor TLR1:TLR2 Cascade Gene Set From Reactome Pathways 2024 proteins participating in the Toll Like Receptor TLR1:TLR2 Cascade pathway from the Reactome Pathways 2024 dataset.
Toll Like Receptor TLR6:TLR2 Cascade Gene Set From Reactome Pathways 2024 proteins participating in the Toll Like Receptor TLR6:TLR2 Cascade pathway from the Reactome Pathways 2024 dataset.
toll-like receptor TLR6:TLR2 signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the toll-like receptor TLR6:TLR2 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
toll-like receptor TLR1:TLR2 signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the toll-like receptor TLR1:TLR2 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.