VAV1

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Results for "VAV1": 1 gene, 8 gene sets

Name
VAV1 Gene vav 1 guanine nucleotide exchange factor This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
vav1 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term vav1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
VAV1 Gene Set From MSigDB Cancer Gene Co-expression Modules co-expressed genes for VAV1 from the MSigDB Cancer Gene Co-expression Modules dataset.
VAV1 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for VAV1 from the Pathway Commons Protein-Protein Interactions dataset.
VAV1 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the VAV1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
VAV1 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the VAV1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
EPI-1746-1 (VAV1) Gene Set From NURSA Protein Complexes proteins in the EPI-1746-1 (VAV1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.
CD28 dependent Vav1 pathway Gene Set From Reactome Pathways 2014 proteins participating in the CD28 dependent Vav1 pathway pathway from the Reactome Pathways dataset.
CD28 dependent Vav1 pathway Gene Set From Reactome Pathways 2024 proteins participating in the CD28 dependent Vav1 pathway pathway from the Reactome Pathways 2024 dataset.