Harmonizome 3.0

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Spironolactone from the curated CTD Gene-Chemical Interactions dataset.

From DrugBank Drug Targets

interacting proteins for the Spironolactone drug from the curated DrugBank Drug Targets dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term spironolactone in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the spironolactone ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the Spironolactone metabolite from the curated HMDB Metabolites of Enzymes dataset.

From DeepCoverMOA Drug Mechanisms of Action

proteins with high or low expression in Spironolactone relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.

From DGIdb Drug Targets 2026

interacting proteins for the SPIRONOLACTONE drug from theDGIdb Drug Targets 2026 dataset.

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the spironolactone-2226 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the spironolactone-1380 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the spironolactone-5781 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the spironolactone-6255 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the spironolactone-2064 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

From GAD Gene-Disease Associations

genes associated with the disease potassium response to spironolactone in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.