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CCR7 Genechemokine (C-C motif) receptor 7 The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] |
ccr7 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ccr7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
CCR7 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for CCR7 from the Pathway Commons Protein-Protein Interactions dataset. |
CCR7 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the CCR7 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
positive regulation of c-c chemokine receptor ccr7 signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of c-c chemokine receptor ccr7 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of c-c chemokine receptor ccr7 signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of c-c chemokine receptor ccr7 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
ccr7 chemokine receptor binding Gene SetFrom GO Molecular Function Annotations 2015 genes performing the ccr7 chemokine receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
positive regulation of C-C chemokine receptor CCR7 signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of C-C chemokine receptor CCR7 signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of C-C chemokine receptor CCR7 signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of C-C chemokine receptor CCR7 signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
CCR7 chemokine receptor binding Gene SetFrom GO Molecular Function Annotations 2023 genes performing the CCR7 chemokine receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
CCR7+ dendritic cell_Undefined_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the CCR7+ dendritic cell_Undefined_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
positive regulation of C-C chemokine receptor CCR7 signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of C-C chemokine receptor CCR7 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of C-C chemokine receptor CCR7 signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of C-C chemokine receptor CCR7 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
CCR7 chemokine receptor binding Gene SetFrom GO Molecular Function Annotations 2025 genes performing the CCR7 chemokine receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset. |