Name

LOC100287243 Gene

nuclease-sensitive element-binding protein 1 pseudogene

AEN Gene

apoptosis enhancing nuclease

Enables DNA exonuclease activity. Involved in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and response to ionizing radiation. Located in nuclear membrane; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

DNA2 Gene

DNA replication helicase/nuclease 2

This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

FAN1 Gene

FANCD2/FANCI-associated nuclease 1

This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016]

APEX1 Gene

APEX nuclease (multifunctional DNA repair enzyme) 1

The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.[provided by RefSeq, Dec 2019]

APEX2 Gene

APEX nuclease (apurinic/apyrimidinic endonuclease) 2

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]

SND1 Gene

staphylococcal nuclease and tudor domain containing 1

This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016]

MRE11 Gene

MRE11 homolog, double strand break repair nuclease

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

CDIN1 Gene

CDAN1 interacting nuclease 1

This gene encodes a protein with two predicted helix-turn-helix domains. Mutations in this gene were found in families with congenital dyserythropoietic anemia type Ib. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]

GIY-YIG nuclease superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GIY-YIG nuclease superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

nuclease Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nuclease in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

regulation of nuclease activity Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of nuclease activity biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of nuclease activity Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of nuclease activity biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of nuclease activity Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of nuclease activity biological process from the curated GO Biological Process Annotations 2015 dataset.

nuclease activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the nuclease activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Staphylococcal nuclease (SNase-like), OB-fold Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Staphylococcal nuclease (SNase-like), OB-fold protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Harbinger transposase-derived nuclease, animal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Harbinger transposase-derived nuclease, animal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HNH nuclease Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HNH nuclease protein domain from the InterPro Predicted Protein Domain Annotations dataset.

D-site 20S pre-rRNA nuclease Nob1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the D-site 20S pre-rRNA nuclease Nob1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

RNA-induced silencing complex, nuclease component Tudor-SN Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the RNA-induced silencing complex, nuclease component Tudor-SN protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Harbinger transposase-derived nuclease domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Harbinger transposase-derived nuclease domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DNA repair nuclease, XPF-type/Helicase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA repair nuclease, XPF-type/Helicase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

positive regulation of nuclease activity Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of nuclease activity biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of nuclease activity Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of nuclease activity biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of nuclease activity Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of nuclease activity biological process from the curated GO Biological Process Annotations 2023 dataset.

RNA nuclease activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the RNA nuclease activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

nuclease activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the nuclease activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

DNA nuclease activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the DNA nuclease activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

nuclease inhibitor activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the nuclease inhibitor activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

negative regulation of nuclease activity Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of nuclease activity biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of nuclease activity Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of nuclease activity biological process from the curated GO Biological Process Annotations 2025 dataset.

RNA nuclease activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the RNA nuclease activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

nuclease activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the nuclease activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

DNA nuclease activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the DNA nuclease activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

nuclease inhibitor activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the nuclease inhibitor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

swi/snf superfamily-type complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the swi/snf superfamily-type complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

tumor necrosis factor receptor superfamily complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the tumor necrosis factor receptor superfamily complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

swi/snf superfamily-type complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the swi/snf superfamily-type complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

superfamily Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term superfamily in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

positive regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2015 dataset.

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2015

genes participating in the adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2015 dataset.

tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2015

genes participating in the tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2015 dataset.

tumor necrosis factor receptor superfamily complex Gene Set

From GO Cellular Component Annotations 2015

proteins localized to the tumor necrosis factor receptor superfamily complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

swi/snf superfamily-type complex Gene Set

From GO Cellular Component Annotations 2015

proteins localized to the swi/snf superfamily-type complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

tumor necrosis factor receptor superfamily binding Gene Set

From GO Molecular Function Annotations 2015

genes performing the tumor necrosis factor receptor superfamily binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Phosphotyrosine protein phosphatase I superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphotyrosine protein phosphatase I superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alpha-D-phosphohexomutase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alpha-D-phosphohexomutase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Thioesterase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Thioesterase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily, Ras type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily, Ras type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily, Rho type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily, Rho type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IA, REG-2-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IA, REG-2-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tautomerase/MIF superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tautomerase/MIF superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ribosomal protein S19, superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribosomal protein S19, superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily, mitochondrial Rho Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily, mitochondrial Rho protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Histidine phosphatase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histidine phosphatase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IIA, CECR5 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IIA, CECR5 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Quinonprotein alcohol dehydrogenase-like superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Quinonprotein alcohol dehydrogenase-like superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Helicase, superfamily 1/2, ATP-binding domain, DinG/Rad3-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Metallothionein superfamily, eukaryotic Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Metallothionein superfamily, eukaryotic protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Major facilitator superfamily associated domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Major facilitator superfamily associated domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tumor necrosis factor ligand superfamily member 15 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tumor necrosis factor ligand superfamily member 15 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DDE superfamily endonuclease, CENP-B-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DDE superfamily endonuclease, CENP-B-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IIB Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IIB protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IIA Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IIA protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DDT domain superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DDT domain superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

PMP-22/EMP/MP20/Claudin superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the PMP-22/EMP/MP20/Claudin superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Major facilitator superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Major facilitator superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

S-adenosylmethionine synthetase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the S-adenosylmethionine synthetase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Histidine phosphatase superfamily, clade-2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histidine phosphatase superfamily, clade-2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Histidine phosphatase superfamily, clade-1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histidine phosphatase superfamily, clade-1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Na/K/Cl co-transporter superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Na/K/Cl co-transporter superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase,subfamily IIIA Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase,subfamily IIIA protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily, GEM/REM/Rad Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily, GEM/REM/Rad protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IB, PSPase-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IB, PSPase-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Histone deacetylase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histone deacetylase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Helicase superfamily 1/2, ATP-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Helicase superfamily 1/2, ATP-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

4'-phosphopantetheinyl transferase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 4'-phosphopantetheinyl transferase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alcohol dehydrogenase superfamily, zinc-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alcohol dehydrogenase superfamily, zinc-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Crotonase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Crotonase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Major facilitator superfamily domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Major facilitator superfamily domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Selectin superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Selectin superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IIA, hypothetical 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IIA, hypothetical 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IA, CTE7 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IA, CTE7 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glycoside hydrolase superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glycoside hydrolase superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Tumor necrosis factor ligand superfamily member 6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tumor necrosis factor ligand superfamily member 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ferritin-like superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ferritin-like superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily, ARF type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily, ARF type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily, SAR1-type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily, SAR1-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Transthyretin/hydroxyisourate hydrolase, superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transthyretin/hydroxyisourate hydrolase, superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cysteine alpha-hairpin motif superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cysteine alpha-hairpin motif superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily hydrolase, subfamily IIID Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily hydrolase, subfamily IIID protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily, ARF/SAR type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily, ARF/SAR type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Dynamin superfamily Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Dynamin superfamily protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Small GTPase superfamily, Rab type Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Small GTPase superfamily, Rab type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

HAD-superfamily phosphatase, subfamily IIIC Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the HAD-superfamily phosphatase, subfamily IIIC protein domain from the InterPro Predicted Protein Domain Annotations dataset.

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2023 dataset.

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2023

genes participating in the adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2023 dataset.

tumor necrosis factor receptor superfamily binding Gene Set

From GO Molecular Function Annotations 2023

genes performing the tumor necrosis factor receptor superfamily binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

decreased tumor necrosis factor (ligand) superfamily member 11 level Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the decreased tumor necrosis factor (ligand) superfamily member 11 level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

increased tumor necrosis factor receptor superfamily member 11b level Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the increased tumor necrosis factor receptor superfamily member 11b level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

increased tumor necrosis factor (ligand) superfamily member 11 level Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the increased tumor necrosis factor (ligand) superfamily member 11 level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway Gene Set

From Reactome Pathways 2024

proteins participating in the TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway pathway from the Reactome Pathways 2024 dataset.

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2025 dataset.

transforming growth factor beta receptor superfamily signaling pathway Gene Set

From GO Biological Process Annotations 2025

genes participating in the transforming growth factor beta receptor superfamily signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2025 dataset.

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2025

genes participating in the adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2025 dataset.

regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2025 dataset.

regulation of tumor necrosis factor superfamily cytokine production Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of tumor necrosis factor superfamily cytokine production biological process from the curated GO Biological Process Annotations 2025 dataset.

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains biological process from the curated GO Biological Process Annotations 2025 dataset.

tumor necrosis factor receptor superfamily binding Gene Set

From GO Molecular Function Annotations 2025

genes performing the tumor necrosis factor receptor superfamily binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

SWI/SNF superfamily-type complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the SWI/SNF superfamily-type complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Tumor necrosis factor receptor superfamily complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Tumor necrosis factor receptor superfamily complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

SWI/SNF superfamily-type complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the SWI/SNF superfamily-type complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Tumor necrosis factor receptor superfamily complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Tumor necrosis factor receptor superfamily complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.