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IRAK1 Geneinterleukin-1 receptor-associated kinase 1 This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
irak1 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term irak1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
IRAK1 Gene SetFrom KEA Substrates of Kinases substrates of the kinase IRAK1 from the curated KEA Substrates of Kinases dataset. |
IRAK1 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for IRAK1 from the Pathway Commons Protein-Protein Interactions dataset. |
IRAK1 Gene SetFrom PhosphoSitePlus Substrates of Kinases substrates of the kinase IRAK1 from the curated PhosphoSitePlus Substrates of Kinases dataset. |
IRAK1 Gene SetFrom Kinase Library Serine Threonine Kinome Atlas substrates of the kinase IRAK1 from the Kinase Library Serine Threonine Kinome Atlas dataset. |
IRAK1 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the IRAK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
IRAK1 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the IRAK1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
IRAK1-IRAK2 complex Gene Setproteins in the IRAK1-IRAK2 complex protein complex from the CORUM Protein Complexes dataset. |
IRAK1-IRAK3 complex Gene Setproteins in the IRAK1-IRAK3 complex protein complex from the CORUM Protein Complexes dataset. |
IRAK1 recruits IKK complex Gene Setproteins participating in the IRAK1 recruits IKK complex pathway from the Reactome Pathways dataset. |
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Gene Setproteins participating in the IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation pathway from the Reactome Pathways dataset. |
IRAK1 recruits IKK complex Gene Setproteins participating in the IRAK1 recruits IKK complex pathway from the Reactome Pathways 2024 dataset. |
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Gene Setproteins participating in the IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation pathway from the Reactome Pathways 2024 dataset. |