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NODAL Genenodal growth differentiation factor This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016] |
nodal Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term nodal in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
NODAL Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for NODAL from the Pathway Commons Protein-Protein Interactions dataset. |
NODAL Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the NODAL gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
sequestering of nodal from receptor via nodal binding Gene SetFrom GO Biological Process Annotations 2015 genes participating in the sequestering of nodal from receptor via nodal binding biological process from the curated GO Biological Process Annotations 2015 dataset. |
sequestering of nodal from receptor via nodal binding Gene SetFrom GO Biological Process Annotations 2023 genes participating in the sequestering of nodal from receptor via nodal binding biological process from the curated GO Biological Process Annotations 2023 dataset. |
sequestering of nodal from receptor via nodal binding Gene SetFrom GO Biological Process Annotations 2025 genes participating in the sequestering of nodal from receptor via nodal binding biological process from the curated GO Biological Process Annotations 2025 dataset. |
nodal receptor complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the nodal receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. |
detection of nodal flow Gene SetFrom GO Biological Process Annotations 2015 genes participating in the detection of nodal flow biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of nodal signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the nodal signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of nodal signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
nodal signaling pathway involved in determination of left/right asymmetry Gene SetFrom GO Biological Process Annotations 2015 genes participating in the nodal signaling pathway involved in determination of left/right asymmetry biological process from the curated GO Biological Process Annotations 2015 dataset. |
nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Gene SetFrom GO Biological Process Annotations 2015 genes participating in the nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of nodal signaling pathway involved in determination of left/right asymmetry Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of nodal signaling pathway involved in determination of left/right asymmetry biological process from the curated GO Biological Process Annotations 2015 dataset. |
nodal binding Gene SetFrom GO Molecular Function Annotations 2015 genes performing the nodal binding molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
absent nodal flow Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the absent nodal flow phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
Signaling by NODAL Gene Setproteins participating in the Signaling by NODAL pathway from the Reactome Pathways dataset. |
Regulation of signaling by NODAL Gene Setproteins participating in the Regulation of signaling by NODAL pathway from the Reactome Pathways dataset. |
Pediatric Nodal Marginal Zone Lymphoma Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Pediatric Nodal Marginal Zone Lymphoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Nodal Rhythm Disorder Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype Nodal Rhythm Disorder in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Gene SetFrom GO Biological Process Annotations 2023 genes participating in the nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biological process from the curated GO Biological Process Annotations 2023 dataset. |
nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the nodal signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of nodal signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
detection of nodal flow Gene SetFrom GO Biological Process Annotations 2023 genes participating in the detection of nodal flow biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of nodal signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry biological process from the curated GO Biological Process Annotations 2023 dataset. |
nodal signaling pathway involved in determination of left/right asymmetry Gene SetFrom GO Biological Process Annotations 2023 genes participating in the nodal signaling pathway involved in determination of left/right asymmetry biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of nodal signaling pathway involved in determination of left/right asymmetry Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of nodal signaling pathway involved in determination of left/right asymmetry biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of nodal signaling pathway involved in determination of left/right asymmetry Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of nodal signaling pathway involved in determination of left/right asymmetry biological process from the curated GO Biological Process Annotations 2023 dataset. |
absent nodal flow Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the absent nodal flow phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
Regulation of signaling by NODAL Gene Setproteins participating in the Regulation of signaling by NODAL pathway from the Reactome Pathways 2024 dataset. |
Signaling by NODAL Gene Setproteins participating in the Signaling by NODAL pathway from the Reactome Pathways 2024 dataset. |
nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the nodal signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of nodal signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
detection of nodal flow Gene SetFrom GO Biological Process Annotations 2025 genes participating in the detection of nodal flow biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of nodal signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of nodal signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
Nodal marginal zone lymphoma Gene SetFrom DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease Nodal marginal zone lymphoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. |
Nodal receptor complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Nodal receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
Nodal T-follicular helper cell lymphoma Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the Nodal T-follicular helper cell lymphoma phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
EBV-positive nodal T- and NK-cell lymphoma Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the EBV-positive nodal T- and NK-cell lymphoma phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |