| Name |
|---|
Sunitinib-resistant PDGFR mutants Gene Setproteins participating in the Sunitinib-resistant PDGFR mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of PDGFR mutants Gene Setproteins participating in the Drug resistance of PDGFR mutants pathway from the Reactome Pathways 2024 dataset. |
PDGFR mutants bind TKIs Gene Setproteins participating in the PDGFR mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
sunitinib Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical sunitinib from the curated CTD Gene-Chemical Interactions dataset. |
Sunitinib Gene Setinteracting proteins for the Sunitinib drug from the curated DrugBank Drug Targets dataset. |
sunitinib Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term sunitinib in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
pdgfr Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term pdgfr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
sunitinib Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the sunitinib ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
Sunitinib Gene SetFrom HMDB Metabolites of Enzymes interacting proteins for the Sunitinib metabolite from the curated HMDB Metabolites of Enzymes dataset. |
PDGFR-beta signaling pathway Gene SetFrom PID Pathways proteins participating in the PDGFR-beta signaling pathway pathway from the PID Pathways dataset. |
PDGFR-alpha signaling pathway Gene SetFrom PID Pathways proteins participating in the PDGFR-alpha signaling pathway pathway from the PID Pathways dataset. |
Sunitinib Gene SetFrom DeepCoverMOA Drug Mechanisms of Action proteins with high or low expression in Sunitinib relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset. |
PDGFR beta pathway Gene SetFrom WikiPathways Pathways 2024 proteins participating in the PDGFR beta pathway pathway from the WikiPathways Pathways 2024 dataset. |
Signaling by PDGFR in disease Gene Setproteins participating in the Signaling by PDGFR in disease pathway from the Reactome Pathways 2024 dataset. |
SUNITINIB Gene Setinteracting proteins for the SUNITINIB drug from theDGIdb Drug Targets 2026 dataset. |
SUNITINIB MALATE Gene Setinteracting proteins for the SUNITINIB MALATE drug from theDGIdb Drug Targets 2026 dataset. |
mutants Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term mutants in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Setproteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways dataset. |
SMAD2/3 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways dataset. |
TGFBR1 KD Mutants in Cancer Gene Setproteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
AXIN missense mutants destabilize the destruction complex Gene Setproteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR3 mutants Gene Setproteins participating in the Signaling by FGFR3 mutants pathway from the Reactome Pathways dataset. |
APC truncation mutants have impaired AXIN binding Gene Setproteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways dataset. |
APC truncation mutants are not K63 polyubiquitinated Gene Setproteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways dataset. |
S37 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S37 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
Signaling by FGFR2 amplification mutants Gene Setproteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways dataset. |
S33 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S33 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
FBXW7 Mutants and NOTCH1 in Cancer Gene Setproteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 mutants Gene Setproteins participating in the Signaling by FGFR1 mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 fusion mutants Gene Setproteins participating in the Signaling by FGFR1 fusion mutants pathway from the Reactome Pathways dataset. |
TCF7L2 mutants don't bind CTBP Gene Setproteins participating in the TCF7L2 mutants don't bind CTBP pathway from the Reactome Pathways dataset. |
Signaling by FGFR2 mutants Gene Setproteins participating in the Signaling by FGFR2 mutants pathway from the Reactome Pathways dataset. |
RNF mutants show enhanced WNT signaling and proliferation Gene Setproteins participating in the RNF mutants show enhanced WNT signaling and proliferation pathway from the Reactome Pathways dataset. |
Signaling by FGFR4 mutants Gene Setproteins participating in the Signaling by FGFR4 mutants pathway from the Reactome Pathways dataset. |
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
truncated APC mutants destabilize the destruction complex Gene Setproteins participating in the truncated APC mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
AXIN mutants destabilize the destruction complex, activating WNT signaling Gene Setproteins participating in the AXIN mutants destabilize the destruction complex, activating WNT signaling pathway from the Reactome Pathways dataset. |
Activated point mutants of FGFR2 Gene Setproteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways dataset. |
TGFBR2 Kinase Domain Mutants in Cancer Gene Setproteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by FGFR mutants Gene Setproteins participating in the Signaling by FGFR mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 amplification mutants Gene Setproteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways dataset. |
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex Gene Setproteins participating in the phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex pathway from the Reactome Pathways dataset. |
TGFBR1 LBD Mutants in Cancer Gene Setproteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways dataset. |
S45 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S45 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
T41 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the T41 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
AMER1 mutants destabilize the destruction complex Gene Setproteins participating in the AMER1 mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling Gene Setproteins participating in the misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway from the Reactome Pathways dataset. |
SMAD4 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
TGFBR2 MSI Frameshift Mutants in Cancer Gene Setproteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by activated point mutants of FGFR1 Gene Setproteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways dataset. |
Signaling by activated point mutants of FGFR3 Gene Setproteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways dataset. |
misspliced GSK3beta mutants stabilize beta-catenin Gene Setproteins participating in the misspliced GSK3beta mutants stabilize beta-catenin pathway from the Reactome Pathways dataset. |
ALK mutants bind TKIs Gene Setproteins participating in the ALK mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
APC truncation mutants are not K63 polyubiquitinated Gene Setproteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways 2024 dataset. |
APC truncation mutants have impaired AXIN binding Gene Setproteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways 2024 dataset. |
AXIN missense mutants destabilize the destruction complex Gene Setproteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways 2024 dataset. |
Activated point mutants of FGFR2 Gene Setproteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S33 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S33 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S37 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S37 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S45 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S45 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 T41 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 T41 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Gene Setproteins participating in the Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) pathway from the Reactome Pathways 2024 dataset. |
Defective translocation of RB1 mutants to the nucleus Gene Setproteins participating in the Defective translocation of RB1 mutants to the nucleus pathway from the Reactome Pathways 2024 dataset. |
Drug resistance in ERBB2 KD mutants Gene Setproteins participating in the Drug resistance in ERBB2 KD mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance in ERBB2 TMD/JMD mutants Gene Setproteins participating in the Drug resistance in ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of ALK mutants Gene Setproteins participating in the Drug resistance of ALK mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of FLT3 mutants Gene Setproteins participating in the Drug resistance of FLT3 mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of KIT mutants Gene Setproteins participating in the Drug resistance of KIT mutants pathway from the Reactome Pathways 2024 dataset. |
FBXW7 Mutants and NOTCH1 in Cancer Gene Setproteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways 2024 dataset. |
FLT3 mutants bind TKIs Gene Setproteins participating in the FLT3 mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
FLT3 signaling by CBL mutants Gene Setproteins participating in the FLT3 signaling by CBL mutants pathway from the Reactome Pathways 2024 dataset. |
Hh mutants abrogate ligand secretion Gene Setproteins participating in the Hh mutants abrogate ligand secretion pathway from the Reactome Pathways 2024 dataset. |
Hh mutants are degraded by ERAD Gene Setproteins participating in the Hh mutants are degraded by ERAD pathway from the Reactome Pathways 2024 dataset. |
KIT mutants bind TKIs Gene Setproteins participating in the KIT mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
RAS GTPase cycle mutants Gene Setproteins participating in the RAS GTPase cycle mutants pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to AEE788 Gene Setproteins participating in the Resistance of ERBB2 KD mutants to AEE788 pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to afatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to afatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to lapatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to lapatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to neratinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to neratinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to osimertinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to osimertinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to sapitinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to sapitinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to tesevatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to tesevatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to trastuzumab Gene Setproteins participating in the Resistance of ERBB2 KD mutants to trastuzumab pathway from the Reactome Pathways 2024 dataset. |
SMAD2/3 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Setproteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
SMAD4 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
STAT5 activation downstream of FLT3 ITD mutants Gene Setproteins participating in the STAT5 activation downstream of FLT3 ITD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ALK fusions and activated point mutants Gene Setproteins participating in the Signaling by ALK fusions and activated point mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by AMER1 mutants Gene Setproteins participating in the Signaling by AMER1 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by APC mutants Gene Setproteins participating in the Signaling by APC mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by AXIN mutants Gene Setproteins participating in the Signaling by AXIN mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by CTNNB1 phospho-site mutants Gene Setproteins participating in the Signaling by CTNNB1 phospho-site mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 ECD mutants Gene Setproteins participating in the Signaling by ERBB2 ECD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 KD Mutants Gene Setproteins participating in the Signaling by ERBB2 KD Mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 TMD/JMD mutants Gene Setproteins participating in the Signaling by ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FGFR1 amplification mutants Gene Setproteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FGFR2 amplification mutants Gene Setproteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FLT3 ITD and TKD mutants Gene Setproteins participating in the Signaling by FLT3 ITD and TKD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by GSK3beta mutants Gene Setproteins participating in the Signaling by GSK3beta mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by LRP5 mutants Gene Setproteins participating in the Signaling by LRP5 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MAP2K mutants Gene Setproteins participating in the Signaling by MAP2K mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MAPK mutants Gene Setproteins participating in the Signaling by MAPK mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MRAS-complex mutants Gene Setproteins participating in the Signaling by MRAS-complex mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by PDGFRA extracellular domain mutants Gene Setproteins participating in the Signaling by PDGFRA extracellular domain mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Gene Setproteins participating in the Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAF1 mutants Gene Setproteins participating in the Signaling by RAF1 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS GAP mutants Gene Setproteins participating in the Signaling by RAS GAP mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS GTPase mutants Gene Setproteins participating in the Signaling by RAS GTPase mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS mutants Gene Setproteins participating in the Signaling by RAS mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RNF43 mutants Gene Setproteins participating in the Signaling by RNF43 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by TCF7L2 mutants Gene Setproteins participating in the Signaling by TCF7L2 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by activated point mutants of FGFR1 Gene Setproteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways 2024 dataset. |
Signaling by activated point mutants of FGFR3 Gene Setproteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways 2024 dataset. |
Signaling by cytosolic FGFR1 fusion mutants Gene Setproteins participating in the Signaling by cytosolic FGFR1 fusion mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by extracellular domain mutants of KIT Gene Setproteins participating in the Signaling by extracellular domain mutants of KIT pathway from the Reactome Pathways 2024 dataset. |
Signaling by high-kinase activity BRAF mutants Gene Setproteins participating in the Signaling by high-kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by juxtamembrane domain KIT mutants Gene Setproteins participating in the Signaling by juxtamembrane domain KIT mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by kinase domain mutants of KIT Gene Setproteins participating in the Signaling by kinase domain mutants of KIT pathway from the Reactome Pathways 2024 dataset. |
Signaling by moderate kinase activity BRAF mutants Gene Setproteins participating in the Signaling by moderate kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants Gene Setproteins participating in the Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling downstream of RAS mutants Gene Setproteins participating in the Signaling downstream of RAS mutants pathway from the Reactome Pathways 2024 dataset. |
TGFBR1 KD Mutants in Cancer Gene Setproteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR1 LBD Mutants in Cancer Gene Setproteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR2 Kinase Domain Mutants in Cancer Gene Setproteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR2 MSI Frameshift Mutants in Cancer Gene Setproteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
