TGFBR2

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Results for "TGFBR2": 1 gene, 13 gene sets

Name
TGFBR2 Gene transforming growth factor, beta receptor II (70/80kDa) The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
tgfbr2 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term tgfbr2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
TGFBR2 Gene Set From KEA Substrates of Kinases substrates of the kinase TGFBR2 from the curated KEA Substrates of Kinases dataset.
TGFBR2 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for TGFBR2 from the Pathway Commons Protein-Protein Interactions dataset.
TGFBR2 Gene Set From PhosphoSitePlus Substrates of Kinases substrates of the kinase TGFBR2 from the curated PhosphoSitePlus Substrates of Kinases dataset.
TGFBR2 Gene Set From Kinase Library Serine Threonine Kinome Atlas substrates of the kinase TGFBR2 from the Kinase Library Serine Threonine Kinome Atlas dataset.
TGFBR2 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the TGFBR2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
TGFBR2 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the TGFBR2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
Loss of Function of TGFBR2 in Cancer Gene Set From Reactome Pathways 2014 proteins participating in the Loss of Function of TGFBR2 in Cancer pathway from the Reactome Pathways dataset.
TGFBR2 Kinase Domain Mutants in Cancer Gene Set From Reactome Pathways 2014 proteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways dataset.
TGFBR2 MSI Frameshift Mutants in Cancer Gene Set From Reactome Pathways 2014 proteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways dataset.
Loss of Function of TGFBR2 in Cancer Gene Set From Reactome Pathways 2024 proteins participating in the Loss of Function of TGFBR2 in Cancer pathway from the Reactome Pathways 2024 dataset.
TGFBR2 Kinase Domain Mutants in Cancer Gene Set From Reactome Pathways 2024 proteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.
TGFBR2 MSI Frameshift Mutants in Cancer Gene Set From Reactome Pathways 2024 proteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.