Name

FLT3 Gene

fms-related tyrosine kinase 3

This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]

FIZ1 Gene

FLT3-interacting zinc finger 1

This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008]

gilteritinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the gilteritinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

FLT3 mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling by CBL mutants Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling by CBL mutants pathway from the Reactome Pathways 2024 dataset.

STAT5 activation downstream of FLT3 ITD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the STAT5 activation downstream of FLT3 ITD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FLT3 ITD and TKD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FLT3 ITD and TKD mutants pathway from the Reactome Pathways 2024 dataset.

GILTERITINIB Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GILTERITINIB drug from theDGIdb Drug Targets 2026 dataset.

GILTERITINIB FUMARATE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GILTERITINIB FUMARATE drug from theDGIdb Drug Targets 2026 dataset.

flt3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term flt3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Flt3 ligand Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Flt3 ligand protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Receptor-type tyrosine-protein kinase FLT3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Receptor-type tyrosine-protein kinase FLT3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

FLT3 Gene Set

From KEA Substrates of Kinases

substrates of the kinase FLT3 from the curated KEA Substrates of Kinases dataset.

FLT3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for FLT3 from the Pathway Commons Protein-Protein Interactions dataset.

FLT3 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase FLT3 from the curated PhosphoSitePlus Substrates of Kinases dataset.

FLT3 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the FLT3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

FLT3 Gene Set

From Kinase Library Tyrosine Kinome Atlas

substrates of the kinase FLT3 from the Kinase Library Tyrosine Kinome Atlas dataset.

FLT3 p Gln640SerfsTer8 signaling Gene Set

From WikiPathways Pathways 2024

proteins participating in the FLT3 p Gln640SerfsTer8 signaling pathway from the WikiPathways Pathways 2024 dataset.

FLT3 Signaling Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 Signaling pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling in disease Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling in disease pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling through SRC family kinases Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling through SRC family kinases pathway from the Reactome Pathways 2024 dataset.

Negative regulation of FLT3 Gene Set

From Reactome Pathways 2024

proteins participating in the Negative regulation of FLT3 pathway from the Reactome Pathways 2024 dataset.

Signaling by FLT3 fusion proteins Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FLT3 fusion proteins pathway from the Reactome Pathways 2024 dataset.

RECOMBINANT FLT3 LIGAND Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the RECOMBINANT FLT3 LIGAND drug from theDGIdb Drug Targets 2026 dataset.

ANTI-FLT3/CD3 BISPECIFIC ANTIBODY CLN-049 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the ANTI-FLT3/CD3 BISPECIFIC ANTIBODY CLN-049 drug from theDGIdb Drug Targets 2026 dataset.

FLT3 INHIBITOR BMF-500 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 INHIBITOR BMF-500 drug from theDGIdb Drug Targets 2026 dataset.

FLT3 INHIBITOR FF-10101 SUCCINATE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 INHIBITOR FF-10101 SUCCINATE drug from theDGIdb Drug Targets 2026 dataset.

FLT3 TYROSINE KINASE INHIBITOR TTT-3002 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 TYROSINE KINASE INHIBITOR TTT-3002 drug from theDGIdb Drug Targets 2026 dataset.

FLT3/ABL/AURORA KINASE INHIBITOR KW-2449 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3/ABL/AURORA KINASE INHIBITOR KW-2449 drug from theDGIdb Drug Targets 2026 dataset.

FLT3/CDK4/6 INHIBITOR FLX925 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3/CDK4/6 INHIBITOR FLX925 drug from theDGIdb Drug Targets 2026 dataset.

mutants Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mutants in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways dataset.

SMAD2/3 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways dataset.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

AXIN missense mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR3 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR3 mutants pathway from the Reactome Pathways dataset.

APC truncation mutants have impaired AXIN binding Gene Set

From Reactome Pathways 2014

proteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways dataset.

APC truncation mutants are not K63 polyubiquitinated Gene Set

From Reactome Pathways 2014

proteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways dataset.

S37 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S37 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

Signaling by FGFR2 amplification mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways dataset.

S33 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S33 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

FBXW7 Mutants and NOTCH1 in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways dataset.

Signaling by FGFR1 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR1 fusion mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 fusion mutants pathway from the Reactome Pathways dataset.

TCF7L2 mutants don't bind CTBP Gene Set

From Reactome Pathways 2014

proteins participating in the TCF7L2 mutants don't bind CTBP pathway from the Reactome Pathways dataset.

Signaling by FGFR2 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR2 mutants pathway from the Reactome Pathways dataset.

RNF mutants show enhanced WNT signaling and proliferation Gene Set

From Reactome Pathways 2014

proteins participating in the RNF mutants show enhanced WNT signaling and proliferation pathway from the Reactome Pathways dataset.

Signaling by FGFR4 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR4 mutants pathway from the Reactome Pathways dataset.

Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

truncated APC mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the truncated APC mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

AXIN mutants destabilize the destruction complex, activating WNT signaling Gene Set

From Reactome Pathways 2014

proteins participating in the AXIN mutants destabilize the destruction complex, activating WNT signaling pathway from the Reactome Pathways dataset.

Activated point mutants of FGFR2 Gene Set

From Reactome Pathways 2014

proteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways dataset.

TGFBR2 Kinase Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by FGFR mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR1 amplification mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways dataset.

phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex pathway from the Reactome Pathways dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways dataset.

S45 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S45 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

T41 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the T41 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

AMER1 mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the AMER1 mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling Gene Set

From Reactome Pathways 2014

proteins participating in the misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway from the Reactome Pathways dataset.

SMAD4 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

TGFBR2 MSI Frameshift Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by activated point mutants of FGFR1 Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways dataset.

Signaling by activated point mutants of FGFR3 Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways dataset.

misspliced GSK3beta mutants stabilize beta-catenin Gene Set

From Reactome Pathways 2014

proteins participating in the misspliced GSK3beta mutants stabilize beta-catenin pathway from the Reactome Pathways dataset.

ALK mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the ALK mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

APC truncation mutants are not K63 polyubiquitinated Gene Set

From Reactome Pathways 2024

proteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways 2024 dataset.

APC truncation mutants have impaired AXIN binding Gene Set

From Reactome Pathways 2024

proteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways 2024 dataset.

AXIN missense mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2024

proteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways 2024 dataset.

Activated point mutants of FGFR2 Gene Set

From Reactome Pathways 2024

proteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways 2024 dataset.

CTNNB1 S33 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S33 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

CTNNB1 S37 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S37 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

CTNNB1 S45 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S45 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

CTNNB1 T41 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 T41 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Gene Set

From Reactome Pathways 2024

proteins participating in the Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) pathway from the Reactome Pathways 2024 dataset.

Defective translocation of RB1 mutants to the nucleus Gene Set

From Reactome Pathways 2024

proteins participating in the Defective translocation of RB1 mutants to the nucleus pathway from the Reactome Pathways 2024 dataset.

Drug resistance in ERBB2 KD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance in ERBB2 KD mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance in ERBB2 TMD/JMD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance in ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of ALK mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of KIT mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of PDGFR mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of PDGFR mutants pathway from the Reactome Pathways 2024 dataset.

FBXW7 Mutants and NOTCH1 in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways 2024 dataset.

Hh mutants abrogate ligand secretion Gene Set

From Reactome Pathways 2024

proteins participating in the Hh mutants abrogate ligand secretion pathway from the Reactome Pathways 2024 dataset.

Hh mutants are degraded by ERAD Gene Set

From Reactome Pathways 2024

proteins participating in the Hh mutants are degraded by ERAD pathway from the Reactome Pathways 2024 dataset.

KIT mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the KIT mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

PDGFR mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the PDGFR mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

RAS GTPase cycle mutants Gene Set

From Reactome Pathways 2024

proteins participating in the RAS GTPase cycle mutants pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to AEE788 Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to AEE788 pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to afatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to afatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to lapatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to lapatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to neratinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to neratinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to osimertinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to osimertinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to sapitinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to sapitinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to tesevatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to tesevatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to trastuzumab Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to trastuzumab pathway from the Reactome Pathways 2024 dataset.

SMAD2/3 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

SMAD4 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by ALK fusions and activated point mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ALK fusions and activated point mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by AMER1 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by AMER1 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by APC mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by APC mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by AXIN mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by AXIN mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by CTNNB1 phospho-site mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by CTNNB1 phospho-site mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 ECD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 ECD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 KD Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 KD Mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 TMD/JMD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FGFR1 amplification mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FGFR2 amplification mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by GSK3beta mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by GSK3beta mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by LRP5 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by LRP5 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MAP2K mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MAP2K mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MAPK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MAPK mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MRAS-complex mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MRAS-complex mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by PDGFRA extracellular domain mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by PDGFRA extracellular domain mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAF1 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAF1 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS GAP mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS GAP mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS GTPase mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS GTPase mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RNF43 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RNF43 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by TCF7L2 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by TCF7L2 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by activated point mutants of FGFR1 Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways 2024 dataset.

Signaling by activated point mutants of FGFR3 Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways 2024 dataset.

Signaling by cytosolic FGFR1 fusion mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by cytosolic FGFR1 fusion mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by extracellular domain mutants of KIT Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by extracellular domain mutants of KIT pathway from the Reactome Pathways 2024 dataset.

Signaling by high-kinase activity BRAF mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by high-kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by juxtamembrane domain KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by juxtamembrane domain KIT mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by kinase domain mutants of KIT Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by kinase domain mutants of KIT pathway from the Reactome Pathways 2024 dataset.

Signaling by moderate kinase activity BRAF mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by moderate kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants pathway from the Reactome Pathways 2024 dataset.

Signaling downstream of RAS mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling downstream of RAS mutants pathway from the Reactome Pathways 2024 dataset.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR2 Kinase Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR2 MSI Frameshift Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.