Harmonizome 3.0

From Allen Brain Atlas

mRNA expression profiles for 6 adult human brain tissue samples spanning ~300 brain structures

From Allen Brain Atlas

mRNA expression profiles for human brain tissue samples spanning 27 time points and 26 brain structures

From Allen Brain Atlas

mRNA expression profiles for human brain tissue samples spanning 31 time points and 26 brain structures

From Allen Brain Atlas

mRNA expression profiles for 4 human prenatal brain tissue samples spanning 4 time points and ~300 brain structures

From BioGPS

mRNA expression profiles for human tissues and cell types

From Jaspar PWMs

Target genes of human transcription factors predicted using known transcription factor binding site motifs

From Hub <strong>Proteinstrong>s

Sets of <strong>proteinstrong>s interacting with hub <strong>proteinstrong>s aggregated from data

From Nuclear Receptor Signaling Atlas

<strong>Proteinstrong>-<strong>proteinstrong> interactions inferred from membership in complexes

From Pathway Commons

<strong>Proteinstrong>-<strong>proteinstrong> interactions from low-throughput or high-throughput studies aggregated by Pathway Commons from the following databases: Reactome, NCI Pathways, PhosphoSite, HumanCyc, HPRD, PANTHER, DIP, BioGRID, IntAct, BIND, Transfac, MiRTarBase, Drugbank, Recon X, Comparative Toxicogenomics Database, and KEGG

From Virus MINT

Interactions between viral and human <strong>proteinstrong>s manually curated from literature

From COMPARTMENTS

<strong>Proteinstrong> subcellular localization evidence scores by manual literature curation

From COMPARTMENTS

<strong>Proteinstrong> subcellular localization evidence scores by integrating experimental data

From COMPARTMENTS

Gene-cellular compartment co-occurrence scores from text-mining biomedical abstracts

From CORUM

<strong>Proteinstrong>s participating in complexes by manual literature curation

From Guide to Pharmacology

<strong>Proteinstrong> ligand-receptor interactions curated by experts

From Human <strong>Proteinstrong> Atlas

Semiquantitative <strong>proteinstrong> expression profiles for tissues

From Human Proteome Map

<strong>Proteinstrong> expression profiles for tissues and cell types

From InterPro

<strong>Proteinstrong> domains predicted for gene products based on sequence similarity to known domain signatures

From LOCATE

Subcellular localization of <strong>proteinstrong>s from low-throughput or high-throughput <strong>proteinstrong> localization assays

From Nuclear Receptor Signaling Atlas

<strong>Proteinstrong>s identified in complexes isolated from cultured cells

From Proteomics Database

<strong>Proteinstrong> expression profiles for tissues and cell types reprocessed from many proteomics datasets

From SILAC Phosphoproteomics

Phosphorylation levels of <strong>proteinstrong>s in cell lines following ligand treatment

From TISSUES

<strong>Proteinstrong> tissue expression evidence scores by manual literature curation

From TISSUES

<strong>Proteinstrong> tissue expression evidence scores by integrating experimental data

From TISSUES

Gene-tissue co-occurrence scores from text-mining biomedical abstracts

From Virus MINT

Interactions between viruses and human <strong>proteinstrong>s manually curated from literature

From LOCATE

Subcellular localization of <strong>proteinstrong>s by sequence similarity to localization sequences

From TISSUES

<strong>Proteinstrong> tissue expression evidence scores by manual literature curation

From TISSUES

<strong>Proteinstrong> tissue expression evidence scores by integrating experimental data

From TISSUES

Gene-tissue co-occurrence scores from text-mining biomedical abstracts

From COMPARTMENTS

<strong>Proteinstrong> subcellular localization evidence scores by manual literature curation

From COMPARTMENTS

<strong>Proteinstrong> subcellular localization evidence scores by integrating experimental data

From COMPARTMENTS

Gene-cellular compartment co-occurrence scores from text-mining biomedical abstracts

From Cell Maps for AI

<strong>Proteinstrong> localization assemblies constructed from integrating AP-MS biomolecular interaction and IF imaging data

From Human <strong>Proteinstrong> Atlas

RNA-seq gene expression profiles for cell lines from HPA

From Human <strong>Proteinstrong> Atlas

RNA-seq gene expression profiles for tissues from HPA

From Human <strong>Proteinstrong> Atlas

RNA-seq gene expression profiles for tissue samples from HPA

From Human Metabolome Database

Biomolecular interactions between metabolites and <strong>proteinstrong>s, such as processing enzymes, curated from literature

From Human Phenotype Ontology

Phenotype-causing gene mutations of human phenotypes from disease knowledgebases

From The Human BioMolecular Atlas Program

Gene-cell type annotations from integrated reference scRNA-seq gene expression profiles

From The Human BioMolecular Atlas Program

Anatomical structure and cell type biomarker annotations from the HuBMAP ASCT+B tables

From The Human BioMolecular Atlas Program

Anatomical structure and cell type biomarker annotations from the HuBMAP ASCT+B tables, augmented with RNA-seq coexpression data from ARCHS4