TIRAP

Filters:

Results for "TIRAP": 1 gene, 12 gene sets

Name
TIRAP Gene toll-interleukin 1 receptor (TIR) domain containing adaptor protein The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
tirap Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term tirap in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
TIRAP Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for TIRAP from the Pathway Commons Protein-Protein Interactions dataset.
TIRAP Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the TIRAP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
TIRAP Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the TIRAP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
tirap-dependent toll-like receptor signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the tirap-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
tirap-dependent toll-like receptor 4 signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the tirap-dependent toll-like receptor 4 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
Toll-interleukin 1 receptor domain-containing adaptor protein, Tirap Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Toll-interleukin 1 receptor domain-containing adaptor protein, Tirap protein domain from the InterPro Predicted Protein Domain Annotations dataset.
TIRAP-dependent toll-like receptor 4 signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the TIRAP-dependent toll-like receptor 4 signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
TIRAP-dependent toll-like receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the TIRAP-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
MyD88:MAL(TIRAP) cascade initiated on plasma membrane Gene Set From Reactome Pathways 2024 proteins participating in the MyD88:MAL(TIRAP) cascade initiated on plasma membrane pathway from the Reactome Pathways 2024 dataset.
TIRAP-dependent toll-like receptor 4 signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the TIRAP-dependent toll-like receptor 4 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
TIRAP-dependent toll-like receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the TIRAP-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.