Harmonizome 3.0

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term caspase in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Biocarta Pathways

proteins participating in the caspase cascade in apoptosis pathway from the Biocarta Pathways dataset.

From ClinVar Gene-Phenotype Associations

genes associated with the Caspase-8 deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

From CORUM Protein Complexes

proteins in the Caspase-2-TRAF2-RIP1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the AK2-FADD-caspase-10 (AFAC10) complex protein complex from the CORUM Protein Complexes dataset.

From GO Molecular Function Annotations 2015

genes performing the caspase binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Raptor N-terminal CASPase-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Caspase-3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase C14A, caspase precursor p45, core protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase C14, caspase non-catalytic subunit p10 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidase C14, caspase domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Caspase, interleukin-1 beta convertase-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Caspase-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From PID Pathways

proteins participating in the Caspase Cascade in Apoptosis pathway from the PID Pathways dataset.

From Reactome Pathways 2014

proteins participating in the SMAC-mediated dissociation of IAP:caspase complexes pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Caspase-mediated cleavage of cytoskeletal proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Caspase-8 activation by cleavage pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 pathway from the Reactome Pathways dataset.

From GO Cellular Component Annotations 2023

proteins localized to the caspase complex cellular component from the curated GO Cellular Component Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the caspase binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From Reactome Pathways 2024

proteins participating in the Caspase activation via Death Receptors in the presence of ligand pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Caspase activation via Dependence Receptors in the absence of ligand pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Caspase activation via extrinsic apoptotic signalling pathway pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Caspase-mediated cleavage of cytoskeletal proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the TP53 Regulates Transcription of Caspase Activators and Caspases pathway from the Reactome Pathways 2024 dataset.

From GO Cellular Component Annotations 2025

proteins localized to the caspase complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the caspase binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Caspase complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Caspase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Response to carboplatin and paclitaxel in ovarian cancer (Caspase 3/7 EC50) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Response to paclitaxel in ovarian cancer (Caspase 3/7 EC50) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the CASPASE INHIBITOR drug from theDGIdb Drug Targets 2026 dataset.