Harmonizome 3.0

From DrugBank

Sets of proteins targeted by drugs by manual literature curation

From DeepCoverMOA

Protein expression profiles in HCT116 cell line following drug treatment

From RummaGEO

Drug perturbation signatures produced from automatically mined RNA-seq samples from GEO.

From Novartis Institutes for Biomedical Research

Drug perturbation signatures created by profiling 4343 small molecules in the U2-OS cell line with the DRUG-seq platform

From Sci-Plex

sciRNA-seq expression profiles for A549, K562, and MCF7 cells treated with 188 compounds at 4 doses

From Drug-Gene Interaction Database

Sets of proteins targeted by drugs by data aggregation

From Biocarta

Sets of proteins participating in pathways from Biocarta

From HumanCyc

Sets of proteins participating in pathways from HumanCyc

From Kyoto Encyclopedia of Genes and Genomes

Sets of proteins participating in pathways from KEGG

From PANTHER

Sets of proteins participating in pathways from PANTHER

From Pathway Interaction Database

Sets of proteins participating in pathways from PID

From Reactome

Sets of proteins participating in pathways from Reactome

From WikiPathways

Sets of proteins participating in pathways from WikiPathways

From WikiPathways

Sets of proteins participating in pathways from WikiPathways updated for 2024

From Reactome

Sets of proteins participating in pathways from Reactome, updated for 2024

From Kyoto Encyclopedia of Genes and Genomes

Sets of proteins participating in pathways from KEGG

From Genomics of Drug Sensitivity in Cancer

mRNA microarray expression profiles for cancer cell lines