Harmonizome 3.0

target of myb1 (chicken)

This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

TP53-target gene 3 protein

cell death-inducing p53 target 1

Predicted to enable zinc ion binding activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Located in cytoplasmic side of late endosome membrane; cytoplasmic side of lysosomal membrane; and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

TP53-target gene 3 protein

Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

mechanistic target of rapamycin (serine/threonine kinase)

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Inhibitors of mTOR are used in organ transplants as immunosuppressants, and are being evaluated for their therapeutic potential in SARS-CoV-2 infections. Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Aug 2020]

TP53 target 3B pseudogene

TP53-target gene 3 protein

Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

TP53 target 5

Predicted to be involved in intracellular signal transduction and negative regulation of cell growth. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Mar 2025]

TP53 target 3

Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

TP53 target 1 (non-protein coding)

TP53-target gene 3 protein

TP53 target 3D

Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

TP53 target 3B

Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

TP53 target 3C

Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

myc target 1

Predicted to act upstream of or within hematopoietic stem cell homeostasis. Located in nuclear body. [provided by Alliance of Genome Resources, Mar 2025]

chromatin target of PRMT1

This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2015]

target of EGR1, member 1 (nuclear)

Enables poly(A)-specific ribonuclease activity and snRNA binding activity. Involved in snRNA 3'-end processing. Located in Cajal body and cytoplasm. Implicated in pontocerebellar hypoplasia type 7. [provided by Alliance of Genome Resources, Mar 2025]

TP53 target 3 family member E

Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Target of Myb1-like 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the axon target recognition biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of transcription of notch receptor target biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the synaptic target recognition biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of hh target transcription factor activity biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the golgi vesicle fusion to target membrane biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2015 dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Target SNARE coiled-coil domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Myc target protein 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Target of Myb protein 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the TP53-target gene 5 protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Domain of unknown function DUF3385, target of rapamycin protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From PID Pathways

proteins participating in the Regulation of nuclear beta catenin signaling and target gene transcription pathway from the PID Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Association of TriC/CCT with target proteins during biosynthesis pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the binding of TCF/LEF:CTNNB1 to target gene promoters pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the repression of WNT target genes pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Ficolins bind to repetitive carbohydrate structures on the target cell surface pathway from the Reactome Pathways dataset.

From GO Biological Process Annotations 2023

genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the T cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of hh target transcription factor activity biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of transcription of Notch receptor target biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the Golgi vesicle fusion to target membrane biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of hh target transcription factor activity biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of T cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the engulfment of target by autophagosome biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of T cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2023 dataset.

From SynGO Synaptic Gene Annotations

genes associated with the synaptic term synaptic target recognition from the SynGO Synaptic Gene Annotations dataset.

From WikiPathways Pathways 2024

proteins participating in the Target of rapamycin signaling pathway from the WikiPathways Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Association of TriC/CCT with target proteins during biosynthesis pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Binding of TCF/LEF:CTNNB1 to target gene promoters pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the E3 ubiquitin ligases ubiquitinate target proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Ficolins bind to repetitive carbohydrate structures on the target cell surface pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the NPAS4 regulates expression of target genes pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Repression of WNT target genes pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SUMO E3 ligases SUMOylate target proteins pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the T cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of hh target transcription factor activity biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of transcription of Notch receptor target biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the Golgi vesicle fusion to target membrane biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of T cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the engulfment of target by autophagosome biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of natural killer cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of T cell mediated cytotoxicity directed against tumor cell target biological process from the curated GO Biological Process Annotations 2025 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC9287735-mmc2.xlsx-NGR1-target-MI_network-node1_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC9287735-mmc2.xlsx-NGR1-target-MI_network-node2_MITF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC12451251-BMRI-2025-9283631-s001.xlsx-Target-STAT3_STAT3 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.