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ALK Geneanaplastic lymphoma receptor tyrosine kinase This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011] |
ALKAL1 GeneALK and LTK ligand 1 Enables protein tyrosine kinase activator activity and signaling receptor binding activity. Involved in cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of MAPK cascade; and positive regulation of neuron projection development. Is active in extracellular space. [provided by Alliance of Genome Resources, Mar 2025] |
ALKAL2 GeneALK and LTK ligand 2 Enables protein tyrosine kinase activator activity and signaling receptor binding activity. Involved in cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of MAPK cascade; and positive regulation of neuron projection development. Is active in extracellular space. [provided by Alliance of Genome Resources, Mar 2025] |
brigatinib-resistant ALK mutants Gene Setproteins participating in the brigatinib-resistant ALK mutants pathway from the Reactome Pathways 2024 dataset. |
ALK mutants bind TKIs Gene Setproteins participating in the ALK mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of ALK mutants Gene Setproteins participating in the Drug resistance of ALK mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ALK fusions and activated point mutants Gene Setproteins participating in the Signaling by ALK fusions and activated point mutants pathway from the Reactome Pathways 2024 dataset. |
BRIGATINIB Gene Setinteracting proteins for the BRIGATINIB drug from theDGIdb Drug Targets 2026 dataset. |
alk in cardiac myocytes Gene SetFrom Biocarta Pathways proteins participating in the alk in cardiac myocytes pathway from the Biocarta Pathways dataset. |
alk Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term alk in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
ALK tyrosine kinase receptor Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the ALK tyrosine kinase receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Nuclear-interacting partner of ALK/Rsm1-like Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Nuclear-interacting partner of ALK/Rsm1-like protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
ALK Gene SetFrom KEA Substrates of Kinases substrates of the kinase ALK from the curated KEA Substrates of Kinases dataset. |
ALK Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for ALK from the Pathway Commons Protein-Protein Interactions dataset. |
ALK Gene SetFrom PhosphoSitePlus Substrates of Kinases substrates of the kinase ALK from the curated PhosphoSitePlus Substrates of Kinases dataset. |
Alk Positive Large B-Cell Lymphoma Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Alk Positive Large B-Cell Lymphoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
ALK Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the ALK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
ALK Gene SetFrom Kinase Library Tyrosine Kinome Atlas substrates of the kinase ALK from the Kinase Library Tyrosine Kinome Atlas dataset. |
MDK and PTN in ALK signaling Gene Setproteins participating in the MDK and PTN in ALK signaling pathway from the Reactome Pathways 2024 dataset. |
Nuclear events stimulated by ALK signaling in cancer Gene Setproteins participating in the Nuclear events stimulated by ALK signaling in cancer pathway from the Reactome Pathways 2024 dataset. |
STAT3 nuclear events downstream of ALK signaling Gene Setproteins participating in the STAT3 nuclear events downstream of ALK signaling pathway from the Reactome Pathways 2024 dataset. |
Signaling by ALK Gene Setproteins participating in the Signaling by ALK pathway from the Reactome Pathways 2024 dataset. |
Signaling by ALK in cancer Gene Setproteins participating in the Signaling by ALK in cancer pathway from the Reactome Pathways 2024 dataset. |
ALK INHIBITOR ASP3026 Gene Setinteracting proteins for the ALK INHIBITOR ASP3026 drug from theDGIdb Drug Targets 2026 dataset. |
ALK INHIBITOR NVL-655 Gene Setinteracting proteins for the ALK INHIBITOR NVL-655 drug from theDGIdb Drug Targets 2026 dataset. |
ALK INHIBITOR TAE684 Gene Setinteracting proteins for the ALK INHIBITOR TAE684 drug from theDGIdb Drug Targets 2026 dataset. |
ALK/C-MET INHIBITOR TQ-B3139 Gene Setinteracting proteins for the ALK/C-MET INHIBITOR TQ-B3139 drug from theDGIdb Drug Targets 2026 dataset. |
mutants Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term mutants in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Setproteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways dataset. |
SMAD2/3 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways dataset. |
TGFBR1 KD Mutants in Cancer Gene Setproteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
AXIN missense mutants destabilize the destruction complex Gene Setproteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR3 mutants Gene Setproteins participating in the Signaling by FGFR3 mutants pathway from the Reactome Pathways dataset. |
APC truncation mutants have impaired AXIN binding Gene Setproteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways dataset. |
APC truncation mutants are not K63 polyubiquitinated Gene Setproteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways dataset. |
S37 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S37 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
Signaling by FGFR2 amplification mutants Gene Setproteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways dataset. |
S33 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S33 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
FBXW7 Mutants and NOTCH1 in Cancer Gene Setproteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 mutants Gene Setproteins participating in the Signaling by FGFR1 mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 fusion mutants Gene Setproteins participating in the Signaling by FGFR1 fusion mutants pathway from the Reactome Pathways dataset. |
TCF7L2 mutants don't bind CTBP Gene Setproteins participating in the TCF7L2 mutants don't bind CTBP pathway from the Reactome Pathways dataset. |
Signaling by FGFR2 mutants Gene Setproteins participating in the Signaling by FGFR2 mutants pathway from the Reactome Pathways dataset. |
RNF mutants show enhanced WNT signaling and proliferation Gene Setproteins participating in the RNF mutants show enhanced WNT signaling and proliferation pathway from the Reactome Pathways dataset. |
Signaling by FGFR4 mutants Gene Setproteins participating in the Signaling by FGFR4 mutants pathway from the Reactome Pathways dataset. |
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
truncated APC mutants destabilize the destruction complex Gene Setproteins participating in the truncated APC mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
AXIN mutants destabilize the destruction complex, activating WNT signaling Gene Setproteins participating in the AXIN mutants destabilize the destruction complex, activating WNT signaling pathway from the Reactome Pathways dataset. |
Activated point mutants of FGFR2 Gene Setproteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways dataset. |
TGFBR2 Kinase Domain Mutants in Cancer Gene Setproteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by FGFR mutants Gene Setproteins participating in the Signaling by FGFR mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 amplification mutants Gene Setproteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways dataset. |
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex Gene Setproteins participating in the phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex pathway from the Reactome Pathways dataset. |
TGFBR1 LBD Mutants in Cancer Gene Setproteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways dataset. |
S45 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S45 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
T41 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the T41 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
AMER1 mutants destabilize the destruction complex Gene Setproteins participating in the AMER1 mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling Gene Setproteins participating in the misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway from the Reactome Pathways dataset. |
SMAD4 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
TGFBR2 MSI Frameshift Mutants in Cancer Gene Setproteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by activated point mutants of FGFR1 Gene Setproteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways dataset. |
Signaling by activated point mutants of FGFR3 Gene Setproteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways dataset. |
misspliced GSK3beta mutants stabilize beta-catenin Gene Setproteins participating in the misspliced GSK3beta mutants stabilize beta-catenin pathway from the Reactome Pathways dataset. |
APC truncation mutants are not K63 polyubiquitinated Gene Setproteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways 2024 dataset. |
APC truncation mutants have impaired AXIN binding Gene Setproteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways 2024 dataset. |
AXIN missense mutants destabilize the destruction complex Gene Setproteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways 2024 dataset. |
Activated point mutants of FGFR2 Gene Setproteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S33 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S33 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S37 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S37 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S45 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S45 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 T41 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 T41 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Gene Setproteins participating in the Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) pathway from the Reactome Pathways 2024 dataset. |
Defective translocation of RB1 mutants to the nucleus Gene Setproteins participating in the Defective translocation of RB1 mutants to the nucleus pathway from the Reactome Pathways 2024 dataset. |
Drug resistance in ERBB2 KD mutants Gene Setproteins participating in the Drug resistance in ERBB2 KD mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance in ERBB2 TMD/JMD mutants Gene Setproteins participating in the Drug resistance in ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of FLT3 mutants Gene Setproteins participating in the Drug resistance of FLT3 mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of KIT mutants Gene Setproteins participating in the Drug resistance of KIT mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of PDGFR mutants Gene Setproteins participating in the Drug resistance of PDGFR mutants pathway from the Reactome Pathways 2024 dataset. |
FBXW7 Mutants and NOTCH1 in Cancer Gene Setproteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways 2024 dataset. |
FLT3 mutants bind TKIs Gene Setproteins participating in the FLT3 mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
FLT3 signaling by CBL mutants Gene Setproteins participating in the FLT3 signaling by CBL mutants pathway from the Reactome Pathways 2024 dataset. |
Hh mutants abrogate ligand secretion Gene Setproteins participating in the Hh mutants abrogate ligand secretion pathway from the Reactome Pathways 2024 dataset. |
Hh mutants are degraded by ERAD Gene Setproteins participating in the Hh mutants are degraded by ERAD pathway from the Reactome Pathways 2024 dataset. |
KIT mutants bind TKIs Gene Setproteins participating in the KIT mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
PDGFR mutants bind TKIs Gene Setproteins participating in the PDGFR mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
RAS GTPase cycle mutants Gene Setproteins participating in the RAS GTPase cycle mutants pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to AEE788 Gene Setproteins participating in the Resistance of ERBB2 KD mutants to AEE788 pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to afatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to afatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to lapatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to lapatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to neratinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to neratinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to osimertinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to osimertinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to sapitinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to sapitinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to tesevatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to tesevatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to trastuzumab Gene Setproteins participating in the Resistance of ERBB2 KD mutants to trastuzumab pathway from the Reactome Pathways 2024 dataset. |
SMAD2/3 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Setproteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
SMAD4 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
STAT5 activation downstream of FLT3 ITD mutants Gene Setproteins participating in the STAT5 activation downstream of FLT3 ITD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by AMER1 mutants Gene Setproteins participating in the Signaling by AMER1 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by APC mutants Gene Setproteins participating in the Signaling by APC mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by AXIN mutants Gene Setproteins participating in the Signaling by AXIN mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by CTNNB1 phospho-site mutants Gene Setproteins participating in the Signaling by CTNNB1 phospho-site mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 ECD mutants Gene Setproteins participating in the Signaling by ERBB2 ECD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 KD Mutants Gene Setproteins participating in the Signaling by ERBB2 KD Mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 TMD/JMD mutants Gene Setproteins participating in the Signaling by ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FGFR1 amplification mutants Gene Setproteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FGFR2 amplification mutants Gene Setproteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FLT3 ITD and TKD mutants Gene Setproteins participating in the Signaling by FLT3 ITD and TKD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by GSK3beta mutants Gene Setproteins participating in the Signaling by GSK3beta mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by LRP5 mutants Gene Setproteins participating in the Signaling by LRP5 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MAP2K mutants Gene Setproteins participating in the Signaling by MAP2K mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MAPK mutants Gene Setproteins participating in the Signaling by MAPK mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MRAS-complex mutants Gene Setproteins participating in the Signaling by MRAS-complex mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by PDGFRA extracellular domain mutants Gene Setproteins participating in the Signaling by PDGFRA extracellular domain mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Gene Setproteins participating in the Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAF1 mutants Gene Setproteins participating in the Signaling by RAF1 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS GAP mutants Gene Setproteins participating in the Signaling by RAS GAP mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS GTPase mutants Gene Setproteins participating in the Signaling by RAS GTPase mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS mutants Gene Setproteins participating in the Signaling by RAS mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RNF43 mutants Gene Setproteins participating in the Signaling by RNF43 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by TCF7L2 mutants Gene Setproteins participating in the Signaling by TCF7L2 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by activated point mutants of FGFR1 Gene Setproteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways 2024 dataset. |
Signaling by activated point mutants of FGFR3 Gene Setproteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways 2024 dataset. |
Signaling by cytosolic FGFR1 fusion mutants Gene Setproteins participating in the Signaling by cytosolic FGFR1 fusion mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by extracellular domain mutants of KIT Gene Setproteins participating in the Signaling by extracellular domain mutants of KIT pathway from the Reactome Pathways 2024 dataset. |
Signaling by high-kinase activity BRAF mutants Gene Setproteins participating in the Signaling by high-kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by juxtamembrane domain KIT mutants Gene Setproteins participating in the Signaling by juxtamembrane domain KIT mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by kinase domain mutants of KIT Gene Setproteins participating in the Signaling by kinase domain mutants of KIT pathway from the Reactome Pathways 2024 dataset. |
Signaling by moderate kinase activity BRAF mutants Gene Setproteins participating in the Signaling by moderate kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants Gene Setproteins participating in the Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling downstream of RAS mutants Gene Setproteins participating in the Signaling downstream of RAS mutants pathway from the Reactome Pathways 2024 dataset. |
TGFBR1 KD Mutants in Cancer Gene Setproteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR1 LBD Mutants in Cancer Gene Setproteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR2 Kinase Domain Mutants in Cancer Gene Setproteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR2 MSI Frameshift Mutants in Cancer Gene Setproteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
