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CAV2 Genecaveolin 2 The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011] |
CAV3 Genecaveolin 3 This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. [provided by RefSeq, Jul 2008] |
CAV1 Genecaveolin 1, caveolae protein, 22kDa The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010] |
caveolin-mediated endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the caveolin-mediated endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
caveolin-mediated endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the caveolin-mediated endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
caveolin-mediated endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the caveolin-mediated endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
Caveolin-1 homodimer complex Gene Setproteins in the Caveolin-1 homodimer complex protein complex from the CORUM Protein Complexes dataset. |
Beta-dystroglycan-caveolin-3 complex Gene Setproteins in the Beta-dystroglycan-caveolin-3 complex protein complex from the CORUM Protein Complexes dataset. |
caveolin Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term caveolin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Caveolin Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Caveolin protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Caveolin-1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Caveolin-1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Caveolin, conserved site Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Caveolin, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
caveolin-1 Gene SetFrom Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term caveolin-1 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset. |
endocytosis Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term endocytosis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
regulation of synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
endocytosis involved in viral entry into host cell Gene SetFrom GO Biological Process Annotations 2015 genes participating in the endocytosis involved in viral entry into host cell biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset. |
endocytosis Gene SetFrom Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term endocytosis in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset. |
Entry of Influenza Virion into Host Cell via Endocytosis Gene Setproteins participating in the Entry of Influenza Virion into Host Cell via Endocytosis pathway from the Reactome Pathways dataset. |
Transferrin endocytosis and recycling Gene Setproteins participating in the Transferrin endocytosis and recycling pathway from the Reactome Pathways dataset. |
ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of clathrin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of clathrin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
clathrin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the clathrin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of clathrin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of clathrin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of clathrin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of clathrin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
clathrin-dependent synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the clathrin-dependent synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
clathrin-dependent endocytosis of virus by host cell Gene SetFrom GO Biological Process Annotations 2023 genes participating in the clathrin-dependent endocytosis of virus by host cell biological process from the curated GO Biological Process Annotations 2023 dataset. |
presynaptic endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the presynaptic endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
postsynaptic endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the postsynaptic endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2023 dataset. |
abnormal endocytosis Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal endocytosis phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal synaptic vesicle endocytosis Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal synaptic vesicle endocytosis phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
presynaptic endocytosis Gene SetFrom SynGO Synaptic Gene Annotations genes associated with the synaptic term presynaptic endocytosis from the SynGO Synaptic Gene Annotations dataset. |
regulation of synaptic vesicle endocytosis Gene SetFrom SynGO Synaptic Gene Annotations genes associated with the synaptic term regulation of synaptic vesicle endocytosis from the SynGO Synaptic Gene Annotations dataset. |
regulation of postsynaptic neurotransmitter receptor endocytosis Gene SetFrom SynGO Synaptic Gene Annotations genes associated with the synaptic term regulation of postsynaptic neurotransmitter receptor endocytosis from the SynGO Synaptic Gene Annotations dataset. |
synaptic vesicle endocytosis Gene SetFrom SynGO Synaptic Gene Annotations genes associated with the synaptic term synaptic vesicle endocytosis from the SynGO Synaptic Gene Annotations dataset. |
postsynaptic neurotransmitter receptor endocytosis Gene SetFrom SynGO Synaptic Gene Annotations genes associated with the synaptic term postsynaptic neurotransmitter receptor endocytosis from the SynGO Synaptic Gene Annotations dataset. |
postsynaptic endocytosis Gene SetFrom SynGO Synaptic Gene Annotations genes associated with the synaptic term postsynaptic endocytosis from the SynGO Synaptic Gene Annotations dataset. |
Entry of Influenza Virion into Host Cell via Endocytosis Gene Setproteins participating in the Entry of Influenza Virion into Host Cell via Endocytosis pathway from the Reactome Pathways 2024 dataset. |
Transferrin endocytosis and recycling Gene Setproteins participating in the Transferrin endocytosis and recycling pathway from the Reactome Pathways 2024 dataset. |
ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of clathrin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of clathrin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
clathrin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the clathrin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of clathrin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of clathrin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
clathrin coat assembly involved in endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the clathrin coat assembly involved in endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of clathrin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of clathrin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
endocytosis involved in viral entry into host cell Gene SetFrom GO Biological Process Annotations 2025 genes participating in the endocytosis involved in viral entry into host cell biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
clathrin-dependent endocytosis of virus by host cell Gene SetFrom GO Biological Process Annotations 2025 genes participating in the clathrin-dependent endocytosis of virus by host cell biological process from the curated GO Biological Process Annotations 2025 dataset. |
clathrin-dependent synaptic vesicle endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the clathrin-dependent synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
presynaptic endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the presynaptic endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
postsynaptic endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the postsynaptic endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of ubiquitin-dependent endocytosis Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of ubiquitin-dependent endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset. |
Endocytosis complex Gene SetFrom CM4AI U2OS Cell Map Protein Localization Assemblies proteins comprising Endocytosis complex assembly using integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset. |
Endocytosis Gene SetFrom KEGG Pathways 2026 proteins participating in the Endocytosis pathway from the KEGG Pathways 2026 dataset. |