Harmonizome 3.0

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lck in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein LCK from the curated Hub Proteins Protein-Protein Interactions dataset.

From KEA Substrates of Kinases

substrates of the kinase LCK from the curated KEA Substrates of Kinases dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for LCK from the Pathway Commons Protein-Protein Interactions dataset.

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term lck in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase LCK from the curated PhosphoSitePlus Substrates of Kinases dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the LCK gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From Kinase Library Tyrosine Kinome Atlas

substrates of the kinase LCK from the Kinase Library Tyrosine Kinome Atlas dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the LCK gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From Biocarta Pathways

proteins participating in the lck and fyn tyrosine kinases in initiation of tcr activation pathway from the Biocarta Pathways dataset.

From CORUM Protein Complexes

proteins in the CD20-LCK-FYN-p75/80 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the CD8A-LCK complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the p56(LCK)-CAML complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the CD20-LCK-LYN-FYN-p75/80 complex, (Raji human B cell line) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the LCK-SLP76-PLC-gamma-1-LAT complex, pervanadate-activated protein complex from the CORUM Protein Complexes dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lck-interacting transmembrane adapter 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Severe combined immunodeficiency due to LCK deficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the LCK INHIBITOR drug from theDGIdb Drug Targets 2026 dataset.