Name

MED18 Gene

mediator complex subunit 18

MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

MEMO1P4 Gene

mediator of cell motility 1 pseudogene 4

MEMO1P2 Gene

mediator of cell motility 1 pseudogene 2

MEMO1P3 Gene

mediator of cell motility 1 pseudogene 3

MEMO1P1 Gene

mediator of cell motility 1 pseudogene 1

PVRL1 Gene

poliovirus receptor-related 1 (herpesvirus entry mediator C)

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]

MED13P1 Gene

mediator complex subunit 13 pseudogene 1

MED15P7 Gene

mediator complex subunit 15 pseudogene 7

MED15P6 Gene

mediator complex subunit 15 pseudogene 6

MED15P5 Gene

mediator complex subunit 15 pseudogene 5

MED15P4 Gene

mediator complex subunit 15 pseudogene 4

MED15P1 Gene

mediator complex subunit 15 pseudogene 1

MED15P9 Gene

mediator complex subunit 15 pseudogene 9

MEMO1 Gene

mediator of cell motility 1

Involved in regulation of microtubule-based process. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

RPRM Gene

reprimo, TP53 dependent G2 arrest mediator candidate

Predicted to be involved in regulation of mitotic cell cycle. Predicted to act upstream of or within regulation of cell cycle. Predicted to be located in membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

MED30 Gene

mediator complex subunit 30

The multiprotein TRAP/Mediator complex facilitates gene expression through a wide variety of transcriptional activators. MED30 is a component of this complex that appears to be metazoan specific (Baek et al., 2002 [PubMed 11909976]).[supplied by OMIM, Nov 2010]

MED31 Gene

mediator complex subunit 31

Predicted to enable transcription coregulator activity and ubiquitin protein ligase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within limb development and negative regulation of fibroblast proliferation. Part of core mediator complex. [provided by Alliance of Genome Resources, Mar 2025]

MED23 Gene

mediator complex subunit 23

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]

MED14P1 Gene

mediator complex subunit 14 pseudogene 1

MED12L Gene

mediator complex subunit 12-like

The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010]

GLE1 Gene

GLE1 RNA export mediator

This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

MED1 Gene

mediator complex subunit 1

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]

MED6 Gene

mediator complex subunit 6

Enables transcription coactivator activity and transcription coactivator binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of core mediator complex and mediator complex. [provided by Alliance of Genome Resources, Mar 2025]

MED4 Gene

mediator complex subunit 4

This gene encodes a component of the Mediator complex. The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

MED8 Gene

mediator complex subunit 8

This gene encodes a protein component of the mediator complex, which aids in transcriptional activation through interaction with RNA polymerase II and gene-specific transcription factors. The encoded protein may also function in ubiquitin ligation and protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

MED9 Gene

mediator complex subunit 9

The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

MED28P3 Gene

mediator complex subunit 28 pseudogene 3

MED28P1 Gene

mediator complex subunit 28 pseudogene 1

MED28P7 Gene

mediator complex subunit 28 pseudogene 7

MED28P4 Gene

mediator complex subunit 28 pseudogene 4

MED28P8 Gene

mediator complex subunit 28 pseudogene 8

NEMF Gene

nuclear export mediator factor

This gene encodes a component of the ribosome quality control complex. The encoded protein facilitates the recognition and ubiquitination of stalled 60S subunits by the ubiquitin ligase listerin. A similar protein in fly functions as a tumor suppressor. [provided by RefSeq, Jul 2016]

LOC100420127 Gene

mediator complex subunit 13 pseudogene

WLS Gene

wntless Wnt ligand secretion mediator

Enables Wnt-protein binding activity and identical protein binding activity. Involved in positive regulation of cell communication and protein transport. Located in several cellular components, including Golgi apparatus; early endosome; and endoplasmic reticulum membrane. Implicated in Zaki syndrome. [provided by Alliance of Genome Resources, Mar 2025]

MED10 Gene

mediator complex subunit 10

MED10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

MED11 Gene

mediator complex subunit 11

MED11 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

MED12 Gene

mediator complex subunit 12

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome, also known as FG syndrome, and Lujan-Fryns syndrome. [provided by RefSeq, Aug 2009]

MED13 Gene

mediator complex subunit 13

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008]

MED14 Gene

mediator complex subunit 14

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. [provided by RefSeq, Jul 2008]

MED15 Gene

mediator complex subunit 15

The protein encoded by this gene is a subunit of the multiprotein complexes PC2 and ARC/DRIP and may function as a transcriptional coactivator in RNA polymerase II transcription. This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

MED16 Gene

mediator complex subunit 16

Enables nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Involved in positive regulation of transcription initiation by RNA polymerase II. Located in membrane. Part of core mediator complex and mediator complex. [provided by Alliance of Genome Resources, Mar 2025]

MED17 Gene

mediator complex subunit 17

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008]

MED19 Gene

mediator complex subunit 19

The protein encoded by this gene is a subunit of the Mediator complex, which binds to gene-specific regulatory factors and provides support for the basal RNA polymerase II transcription machinery. This gene has been implicated in the growth of several types of cancer, and inhibition of its expression inhibits the growth and spread of these cancers. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

CRSP8P Gene

mediator complex subunit 27 pseudogene

CRMP1 Gene

collapsin response mediator protein 1

This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

MED7 Gene

mediator complex subunit 7

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

PVRL2 Gene

poliovirus receptor-related 2 (herpesvirus entry mediator B)

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

MED29 Gene

mediator complex subunit 29

MED29 is a subunit of the Mediator complex, a multiprotein coactivator of RNA transcription that interacts with DNA-bound transcriptional activators, RNA polymerase II (see MIM 180660), and general initiation factors (Sato et al., 2003 [PubMed 14576168]).[supplied by OMIM, Aug 2009]

MED28 Gene

mediator complex subunit 28

Predicted to enable actin binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly; positive regulation of transcription elongation by RNA polymerase II; and positive regulation of transcription initiation by RNA polymerase II. Predicted to act upstream of or within negative regulation of smooth muscle cell differentiation and somatic stem cell population maintenance. Located in nucleoplasm. Part of core mediator complex. [provided by Alliance of Genome Resources, Mar 2025]

MED21 Gene

mediator complex subunit 21

This gene encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

MED20 Gene

mediator complex subunit 20

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]

MED22 Gene

mediator complex subunit 22

This gene encodes a protein component of the mediator complex, which functions in the regulation of transcription by bridging interactions between gene-specific regulatory factors, RNA polymerase II, and general transcription factors. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013]

MED25 Gene

mediator complex subunit 25

This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq, Apr 2010]

MED24 Gene

mediator complex subunit 24

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

MED27 Gene

mediator complex subunit 27

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]

MED13L Gene

mediator complex subunit 13-like

The protein encoded by this gene is a subunit of the Mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes. The encoded protein is involved in early development of the heart and brain. Defects in this gene are a cause of transposition of the great arteries, dextro-looped (DTGA).[provided by RefSeq, Jul 2010]

LOC100420144 Gene

mediator of cell motility 1 pseudogene

LOC101101841 Gene

mediator complex subunit 21 pseudogene

MKLN1 Gene

muskelin 1, intracellular mediator containing kelch motifs

Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]

MED26 Gene

mediator complex subunit 26

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008]

CNNM1 Gene

cyclin and CBS domain divalent metal cation transport mediator 1

This gene encodes a member of the ancient conserved domain protein family. The encoded protein may bind copper. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

CNNM3 Gene

cyclin and CBS domain divalent metal cation transport mediator 3

Predicted to enable transmembrane transporter activity. Predicted to be involved in magnesium ion homeostasis. Located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

CNNM2 Gene

cyclin and CBS domain divalent metal cation transport mediator 2

This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

CNNM4 Gene

cyclin and CBS domain divalent metal cation transport mediator 4

This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta. [provided by RefSeq, Feb 2010]

MDC1 Gene

mediator of DNA-damage checkpoint 1

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]

MED6P1 Gene

mediator complex subunit 6 pseudogene 1

STUM Gene

stum, mechanosensory transduction mediator homolog

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

MED18-MED20-MED29 mediator subcomplex Gene Set

From CORUM Protein Complexes

proteins in the MED18-MED20-MED29 mediator subcomplex protein complex from the CORUM Protein Complexes dataset.

Mediator complex, subunit Med18, metazoa/fungi Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med18, metazoa/fungi protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Sur2 subcomplex of mediator Gene Set

From CORUM Protein Complexes

proteins in the Sur2 subcomplex of mediator protein complex from the CORUM Protein Complexes dataset.

regulation of dna damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of dna damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

dna damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the dna damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of dna damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of dna damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

BL2851 (MED18) Gene Set

From NURSA Protein Complexes

proteins in the BL2851 (MED18) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL2854 (MED18) Gene Set

From NURSA Protein Complexes

proteins in the BL2854 (MED18) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL2852 (MED18) Gene Set

From NURSA Protein Complexes

proteins in the BL2852 (MED18) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL2853 (MED18) Gene Set

From NURSA Protein Complexes

proteins in the BL2853 (MED18) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

MED18 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MED18 from the Pathway Commons Protein-Protein Interactions dataset.

MED18 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MED18 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

proteasome regulatory particle, base subcomplex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the proteasome regulatory particle, base subcomplex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

proteasome regulatory particle, lid subcomplex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the proteasome regulatory particle, lid subcomplex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

pwp2p-containing subcomplex of 90s preribosome Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the pwp2p-containing subcomplex of 90s preribosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

COG2-COG3-COG4 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the COG2-COG3-COG4 subcomplex protein complex from the CORUM Protein Complexes dataset.

Binary COG subcomplex Gene Set

From CORUM Protein Complexes

proteins in the Binary COG subcomplex protein complex from the CORUM Protein Complexes dataset.

COG1-COG8-COG5-COG6-COG7 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the COG1-COG8-COG5-COG6-COG7 subcomplex protein complex from the CORUM Protein Complexes dataset.

NPC subcomplex (NUP98, NUP107, NUP133, NUP160) Gene Set

From CORUM Protein Complexes

proteins in the NPC subcomplex (NUP98, NUP107, NUP133, NUP160) protein complex from the CORUM Protein Complexes dataset.

TAF4-TAF12 subcomplex of TFIID complex Gene Set

From CORUM Protein Complexes

proteins in the TAF4-TAF12 subcomplex of TFIID complex protein complex from the CORUM Protein Complexes dataset.

5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex Gene Set

From CORUM Protein Complexes

proteins in the 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex protein complex from the CORUM Protein Complexes dataset.

5S-DNA-TFIIIA-TFIIIC2 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the 5S-DNA-TFIIIA-TFIIIC2 subcomplex protein complex from the CORUM Protein Complexes dataset.

TFIID subcomplex Gene Set

From CORUM Protein Complexes

proteins in the TFIID subcomplex protein complex from the CORUM Protein Complexes dataset.

CTF18-RFC subcomplex Gene Set

From CORUM Protein Complexes

proteins in the CTF18-RFC subcomplex protein complex from the CORUM Protein Complexes dataset.

COG5-COG6-COG7 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the COG5-COG6-COG7 subcomplex protein complex from the CORUM Protein Complexes dataset.

CTF8-DCC1 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the CTF8-DCC1 subcomplex protein complex from the CORUM Protein Complexes dataset.

Tetrameric COG subcomplex Gene Set

From CORUM Protein Complexes

proteins in the Tetrameric COG subcomplex protein complex from the CORUM Protein Complexes dataset.

Nup 107-160 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the Nup 107-160 subcomplex protein complex from the CORUM Protein Complexes dataset.

RFC2-5 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the RFC2-5 subcomplex protein complex from the CORUM Protein Complexes dataset.

SCF subcomplex (WEE1, SKP2, BTRC) Gene Set

From CORUM Protein Complexes

proteins in the SCF subcomplex (WEE1, SKP2, BTRC) protein complex from the CORUM Protein Complexes dataset.

COG1-COG8-COG2-COG3-COG4 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the COG1-COG8-COG2-COG3-COG4 subcomplex protein complex from the CORUM Protein Complexes dataset.

COG1-COG8 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the COG1-COG8 subcomplex protein complex from the CORUM Protein Complexes dataset.

Ternary COG subcomplex Gene Set

From CORUM Protein Complexes

proteins in the Ternary COG subcomplex protein complex from the CORUM Protein Complexes dataset.

TFIID subcomplex, testis-specific Gene Set

From CORUM Protein Complexes

proteins in the TFIID subcomplex, testis-specific protein complex from the CORUM Protein Complexes dataset.

CTF8-CTF18-DCC1 subcomplex Gene Set

From CORUM Protein Complexes

proteins in the CTF8-CTF18-DCC1 subcomplex protein complex from the CORUM Protein Complexes dataset.

subcomplex Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term subcomplex in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

proteasome regulatory particle, base subcomplex Gene Set

From GO Cellular Component Annotations 2015

proteins localized to the proteasome regulatory particle, base subcomplex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

pwp2p-containing subcomplex of 90s preribosome Gene Set

From GO Cellular Component Annotations 2015

proteins localized to the pwp2p-containing subcomplex of 90s preribosome cellular component from the curated GO Cellular Component Annotations 2015 dataset.

proteasome regulatory particle, lid subcomplex Gene Set

From GO Cellular Component Annotations 2015

proteins localized to the proteasome regulatory particle, lid subcomplex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase 1, beta subcomplex, subunit 6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase 1, beta subcomplex, subunit 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Proteasome regulatory particle, lid subcomplex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Proteasome regulatory particle, lid subcomplex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Pwp2p-containing subcomplex of 90S preribosome Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Pwp2p-containing subcomplex of 90S preribosome cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

exon-exon junction subcomplex mago-y14 Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the exon-exon junction subcomplex mago-y14 cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Proteasome regulatory particle, base subcomplex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Proteasome regulatory particle, base subcomplex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Pwp2p-containing subcomplex of 90S preribosome Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Pwp2p-containing subcomplex of 90S preribosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

exon-exon junction subcomplex mago-y14 Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the exon-exon junction subcomplex mago-y14 cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Mitotic checkpoint complex, CDC20-MAD2 subcomplex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Mitotic checkpoint complex, CDC20-MAD2 subcomplex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Proteasome regulatory particle, lid subcomplex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Proteasome regulatory particle, lid subcomplex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Proteasome regulatory particle, base subcomplex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Proteasome regulatory particle, base subcomplex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Nuclear speckle spliceosome subcomplex Gene Set

From CM4AI U2OS Cell Map Protein Localization Assemblies

proteins comprising Nuclear speckle spliceosome subcomplex assembly using integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.

Extracellular matrix organization subcomplex Gene Set

From CM4AI U2OS Cell Map Protein Localization Assemblies

proteins comprising Extracellular matrix organization subcomplex assembly using integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.

dna recombinase mediator complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the dna recombinase mediator complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

mediator complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the mediator complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

dna recombinase mediator complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the dna recombinase mediator complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

mediator complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mediator complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

core mediator complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the core mediator complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

TRAP-SMCC mediator complex Gene Set

From CORUM Protein Complexes

proteins in the TRAP-SMCC mediator complex protein complex from the CORUM Protein Complexes dataset.

Mediator complex Gene Set

From CORUM Protein Complexes

proteins in the Mediator complex protein complex from the CORUM Protein Complexes dataset.

CDK8-CyclinC-Mediator complex Gene Set

From CORUM Protein Complexes

proteins in the CDK8-CyclinC-Mediator complex protein complex from the CORUM Protein Complexes dataset.

ARC92-Mediator complex Gene Set

From CORUM Protein Complexes

proteins in the ARC92-Mediator complex protein complex from the CORUM Protein Complexes dataset.

Mediator complex 2 Gene Set

From CORUM Protein Complexes

proteins in the Mediator complex 2 protein complex from the CORUM Protein Complexes dataset.

CRSP-Mediator 2 complex Gene Set

From CORUM Protein Complexes

proteins in the CRSP-Mediator 2 complex protein complex from the CORUM Protein Complexes dataset.

Mediator complex 1 Gene Set

From CORUM Protein Complexes

proteins in the Mediator complex 1 protein complex from the CORUM Protein Complexes dataset.

mediator Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mediator in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

dna damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the dna damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of dna damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of dna damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of mediator complex assembly Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of mediator complex assembly biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2015 dataset.

production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2015

genes participating in the production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of dna damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of dna damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

dna damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Gene Set

From GO Biological Process Annotations 2015

genes participating in the dna damage response, signal transduction by p53 class mediator resulting in cell cycle arrest biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of mediator complex assembly Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of mediator complex assembly biological process from the curated GO Biological Process Annotations 2015 dataset.

intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

production of molecular mediator involved in inflammatory response Gene Set

From GO Biological Process Annotations 2015

genes participating in the production of molecular mediator involved in inflammatory response biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of dna damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of dna damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2015 dataset.

dna recombinase mediator complex Gene Set

From GO Cellular Component Annotations 2015

proteins localized to the dna recombinase mediator complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

mediator complex Gene Set

From GO Cellular Component Annotations 2015

proteins localized to the mediator complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

transforming growth factor beta receptor, cytoplasmic mediator activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the transforming growth factor beta receptor, cytoplasmic mediator activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

transforming growth factor beta receptor, common-partner cytoplasmic mediator activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the transforming growth factor beta receptor, common-partner cytoplasmic mediator activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

mediator complex binding Gene Set

From GO Molecular Function Annotations 2015

genes performing the mediator complex binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Mediator complex, subunit Med25, PTOV activation and synapsin 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med25, PTOV activation and synapsin 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med13, N-terminal, metazoa/fungi Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med13, N-terminal, metazoa/fungi protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med22 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med22 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med23 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med23 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med21 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med21 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med27 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med27 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med28 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med28 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med12, LCEWAV-domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med12, LCEWAV-domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med8, fungi/metazoa Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med8, fungi/metazoa protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med12, catenin-binding Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med12, catenin-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med30, metazoa Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med30, metazoa protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med24, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med24, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med25, von Willebrand factor type A Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med25, von Willebrand factor type A protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med25, synapsin 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med25, synapsin 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med17 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med17 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med16 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med16 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med25, NR box Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med25, NR box protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med7 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med7 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med4 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med9 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med9 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med13 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med13 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med12 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med12 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med11 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med11 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med10 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med10 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med14 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med14 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med31 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med31 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med19, metazoa Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med19, metazoa protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med15, metazoa Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med15, metazoa protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med1, metazoa/fungi Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med1, metazoa/fungi protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mediator complex, subunit Med6, metazoa/plant Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mediator complex, subunit Med6, metazoa/plant protein domain from the InterPro Predicted Protein Domain Annotations dataset.

regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

DNA damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the DNA damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of DNA damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of DNA damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of DNA damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of DNA damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Gene Set

From GO Biological Process Annotations 2023

genes participating in the DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of DNA damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of DNA damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of mediator complex assembly Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of mediator complex assembly biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of mediator complex assembly Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of mediator complex assembly biological process from the curated GO Biological Process Annotations 2023 dataset.

core mediator complex Gene Set

From GO Cellular Component Annotations 2023

proteins localized to the core mediator complex cellular component from the curated GO Cellular Component Annotations 2023 dataset.

cell adhesion mediator activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the cell adhesion mediator activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

cell-cell adhesion mediator activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the cell-cell adhesion mediator activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

cell-matrix adhesion mediator activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the cell-matrix adhesion mediator activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

DNA damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the DNA damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of DNA damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of DNA damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of DNA damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of DNA damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

regulation of DNA damage response, signal transduction by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of DNA damage response, signal transduction by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of mediator complex assembly Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of mediator complex assembly biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2025 dataset.

regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

regulation of intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2025 dataset.

regulation of production of molecular mediator of immune response Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of production of molecular mediator of immune response biological process from the curated GO Biological Process Annotations 2025 dataset.

regulation of mediator complex assembly Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of mediator complex assembly biological process from the curated GO Biological Process Annotations 2025 dataset.

core mediator complex Gene Set

From GO Cellular Component Annotations 2025

proteins localized to the core mediator complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

cell adhesion mediator activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the cell adhesion mediator activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

cell-cell adhesion mediator activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the cell-cell adhesion mediator activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

cell-matrix adhesion mediator activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the cell-matrix adhesion mediator activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Mediator complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Mediator complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

DNA recombinase mediator complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the DNA recombinase mediator complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Core mediator complex Gene Set

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Core mediator complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

DNA recombinase mediator complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the DNA recombinase mediator complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Mediator complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Mediator complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Core mediator complex Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Core mediator complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

RNA polymerase and mediator super assembly Gene Set

From CM4AI U2OS Cell Map Protein Localization Assemblies

proteins comprising RNA polymerase and mediator super assembly assembly using integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.

Mediator complex Gene Set

From CM4AI U2OS Cell Map Protein Localization Assemblies

proteins comprising Mediator complex assembly using integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.

Inflammatory mediator regulation of TRP channels Gene Set

From KEGG Pathways 2026

proteins participating in the Inflammatory mediator regulation of TRP channels pathway from the KEGG Pathways 2026 dataset.