Name

GCGR Gene

glucagon receptor

The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).[provided by RefSeq, Jan 2010]

GLP2R Gene

glucagon-like peptide 2 receptor

This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]

GCG Gene

glucagon

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]

GLP1R Gene

glucagon-like peptide 1 receptor

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016]

glucagon-(1-21) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the glucagon-(1-21) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

GPCR, family 2, glucagon-like peptide-1/glucagon receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, glucagon-like peptide-1/glucagon receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

abnormality of glucagon secretion Gene Set

From DISEASES Text-mining Gene-Disease Association Evidence Scores

genes co-occuring with the disease abnormality of glucagon secretion in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Glucagon recombinant Gene Set

From DrugBank Drug Targets

interacting proteins for the Glucagon recombinant drug from the curated DrugBank Drug Targets dataset.

impaired glucagon suppression Gene Set

From GAD Gene-Disease Associations

genes associated with the disease impaired glucagon suppression in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

glucagon Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term glucagon in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

cellular response to glucagon stimulus Gene Set

From GO Biological Process Annotations 2015

genes participating in the cellular response to glucagon stimulus biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2015 dataset.

response to glucagon Gene Set

From GO Biological Process Annotations 2015

genes participating in the response to glucagon biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2015 dataset.

glucagon secretion Gene Set

From GO Biological Process Annotations 2015

genes participating in the glucagon secretion biological process from the curated GO Biological Process Annotations 2015 dataset.

glucagon receptor activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the glucagon receptor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

glucagon receptor binding Gene Set

From GO Molecular Function Annotations 2015

genes performing the glucagon receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

[125I]glucagon (human mouse rat) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [125I]glucagon (human mouse rat) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

des-His1-[Leu4-Glu9]glucagon-NH2 Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the des-His1-[Leu4-Glu9]glucagon-NH2 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

des-His1-[Glu9]glucagon-NH2 Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the des-His1-[Glu9]glucagon-NH2 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

glucagon-(1-6) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the glucagon-(1-6) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

GPCR, family 2, glucagon receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, glucagon receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucagon Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucagon protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucagon/GIP/secretin/VIP Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucagon/GIP/secretin/VIP protein domain from the InterPro Predicted Protein Domain Annotations dataset.

GPCR, family 2, glucagon-like peptide-1 receptor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GPCR, family 2, glucagon-like peptide-1 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

abnormal circulating glucagon level Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal circulating glucagon level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

decreased circulating glucagon level Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the decreased circulating glucagon level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

abnormal glucagon secretion Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal glucagon secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

increased circulating glucagon level Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the increased circulating glucagon level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

decreased glucagon secretion Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the decreased glucagon secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

increased glucagon secretion Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the increased glucagon secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Gene Set

From Reactome Pathways 2014

proteins participating in the Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway from the Reactome Pathways dataset.

Glucagon signaling in metabolic regulation Gene Set

From Reactome Pathways 2014

proteins participating in the Glucagon signaling in metabolic regulation pathway from the Reactome Pathways dataset.

PKA activation in glucagon signalling Gene Set

From Reactome Pathways 2014

proteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways dataset.

Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Gene Set

From Reactome Pathways 2014

proteins participating in the Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway from the Reactome Pathways dataset.

Glucagon-type ligand receptors Gene Set

From Reactome Pathways 2014

proteins participating in the Glucagon-type ligand receptors pathway from the Reactome Pathways dataset.

Glucagon Resistance Gene Set

From DisGeNET Gene-Disease Associations

genes associated with the disease Glucagon Resistance in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Increased Glucagon Level Gene Set

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Increased Glucagon Level in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

Glucagon Measurement Gene Set

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Glucagon Measurement in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

Glucagon-Like Peptide-1 Measurement Gene Set

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Glucagon-Like Peptide-1 Measurement in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2023 dataset.

glucagon secretion Gene Set

From GO Biological Process Annotations 2023

genes participating in the glucagon secretion biological process from the curated GO Biological Process Annotations 2023 dataset.

response to glucagon Gene Set

From GO Biological Process Annotations 2023

genes participating in the response to glucagon biological process from the curated GO Biological Process Annotations 2023 dataset.

glucagon processing Gene Set

From GO Biological Process Annotations 2023

genes participating in the glucagon processing biological process from the curated GO Biological Process Annotations 2023 dataset.

cellular response to glucagon stimulus Gene Set

From GO Biological Process Annotations 2023

genes participating in the cellular response to glucagon stimulus biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2023 dataset.

glucagon-like peptide 1 receptor activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the glucagon-like peptide 1 receptor activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

glucagon receptor activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the glucagon receptor activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

glucagon family peptide binding Gene Set

From GO Molecular Function Annotations 2023

genes performing the glucagon family peptide binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

glucagon receptor binding Gene Set

From GO Molecular Function Annotations 2023

genes performing the glucagon receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

increased circulating glucagon level Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the increased circulating glucagon level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

decreased glucagon secretion Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the decreased glucagon secretion phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

decreased circulating glucagon level Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the decreased circulating glucagon level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

increased glucagon secretion Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the increased glucagon secretion phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

abnormal glucagon secretion Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the abnormal glucagon secretion phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

Glucagon signaling in metabolic regulation Gene Set

From Reactome Pathways 2024

proteins participating in the Glucagon signaling in metabolic regulation pathway from the Reactome Pathways 2024 dataset.

Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Gene Set

From Reactome Pathways 2024

proteins participating in the Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway from the Reactome Pathways 2024 dataset.

Glucagon-type ligand receptors Gene Set

From Reactome Pathways 2024

proteins participating in the Glucagon-type ligand receptors pathway from the Reactome Pathways 2024 dataset.

PKA activation in glucagon signalling Gene Set

From Reactome Pathways 2024

proteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways 2024 dataset.

Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Gene Set

From Reactome Pathways 2024

proteins participating in the Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway from the Reactome Pathways 2024 dataset.

regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2025

genes participating in the regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2025 dataset.

cellular response to glucagon stimulus Gene Set

From GO Biological Process Annotations 2025

genes participating in the cellular response to glucagon stimulus biological process from the curated GO Biological Process Annotations 2025 dataset.

glucagon secretion Gene Set

From GO Biological Process Annotations 2025

genes participating in the glucagon secretion biological process from the curated GO Biological Process Annotations 2025 dataset.

response to glucagon Gene Set

From GO Biological Process Annotations 2025

genes participating in the response to glucagon biological process from the curated GO Biological Process Annotations 2025 dataset.

glucagon processing Gene Set

From GO Biological Process Annotations 2025

genes participating in the glucagon processing biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2025 dataset.

negative regulation of glucagon secretion Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of glucagon secretion biological process from the curated GO Biological Process Annotations 2025 dataset.

glucagon-like peptide 1 receptor activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the glucagon-like peptide 1 receptor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

glucagon receptor activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the glucagon receptor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

glucagon family peptide binding Gene Set

From GO Molecular Function Annotations 2025

genes performing the glucagon family peptide binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

glucagon receptor binding Gene Set

From GO Molecular Function Annotations 2025

genes performing the glucagon receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Abnormality of glucagon secretion Gene Set

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occuring with the disease Abnormality of glucagon secretion in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-30 minutes) Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-30 minutes) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Glucagon levels in response to oral glucose tolerance test (120 minutes) Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Glucagon levels in response to oral glucose tolerance test (120 minutes) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Glucagon levels in response to oral glucose tolerance test (fasting) Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Glucagon levels in response to oral glucose tolerance test (fasting) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Glucagon signaling pathway Gene Set

From KEGG Pathways 2026

proteins participating in the Glucagon signaling pathway pathway from the KEGG Pathways 2026 dataset.

GLUCAGON (RDNA) Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GLUCAGON (RDNA) drug from theDGIdb Drug Targets 2026 dataset.

GLUCAGON Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GLUCAGON drug from theDGIdb Drug Targets 2026 dataset.

GLUCAGON HYDROCHLORIDE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GLUCAGON HYDROCHLORIDE drug from theDGIdb Drug Targets 2026 dataset.

[125I]GLUCAGON (HUMAN, MOUSE, RAT) Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the [125I]GLUCAGON (HUMAN, MOUSE, RAT) drug from theDGIdb Drug Targets 2026 dataset.

GLUCAGON-LIKE PEPTIDE 1-(7-36) AMIDE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GLUCAGON-LIKE PEPTIDE 1-(7-36) AMIDE drug from theDGIdb Drug Targets 2026 dataset.

GLUCAGON-LIKE PEPTIDE 1-(7-37) Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GLUCAGON-LIKE PEPTIDE 1-(7-37) drug from theDGIdb Drug Targets 2026 dataset.

GLUCAGON-LIKE PEPTIDE 2 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GLUCAGON-LIKE PEPTIDE 2 drug from theDGIdb Drug Targets 2026 dataset.

GLUCAGON-LIKE PEPTIDE 2-(3-33) Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the GLUCAGON-LIKE PEPTIDE 2-(3-33) drug from theDGIdb Drug Targets 2026 dataset.