replicative senescence

Filters:

Gene Set

Results for "replicative senescence": 98 gene sets

Name
replicative senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the replicative senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
abnormal cellular replicative senescence Gene Set From MPO Gene-Phenotype Associations gene mutations causing the abnormal cellular replicative senescence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
early cellular replicative senescence Gene Set From MPO Gene-Phenotype Associations gene mutations causing the early cellular replicative senescence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
delayed cellular replicative senescence Gene Set From MPO Gene-Phenotype Associations gene mutations causing the delayed cellular replicative senescence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
delayed cellular replicative senescence Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the delayed cellular replicative senescence phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
early cellular replicative senescence Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the early cellular replicative senescence phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
abnormal cellular replicative senescence Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal cellular replicative senescence phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
NAD metabolism in oncogene induced senescence and mitochondrial dysfunction associated senescence Gene Set From WikiPathways Pathways 2024 proteins participating in the NAD metabolism in oncogene induced senescence and mitochondrial dysfunction associated senescence pathway from the WikiPathways Pathways 2024 dataset.
nuclear pre-replicative complex Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the nuclear pre-replicative complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
pre-replicative complex Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the pre-replicative complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
replicative Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term replicative in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
pre-replicative complex assembly involved in cell cycle dna replication Gene Set From GO Biological Process Annotations 2015 genes participating in the pre-replicative complex assembly involved in cell cycle dna replication biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of replicative cell aging Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of replicative cell aging biological process from the curated GO Biological Process Annotations 2015 dataset.
replicative cell aging Gene Set From GO Biological Process Annotations 2015 genes participating in the replicative cell aging biological process from the curated GO Biological Process Annotations 2015 dataset.
pre-replicative complex assembly involved in nuclear cell cycle dna replication Gene Set From GO Biological Process Annotations 2015 genes participating in the pre-replicative complex assembly involved in nuclear cell cycle dna replication biological process from the curated GO Biological Process Annotations 2015 dataset.
pre-replicative complex assembly Gene Set From GO Biological Process Annotations 2015 genes participating in the pre-replicative complex assembly biological process from the curated GO Biological Process Annotations 2015 dataset.
nuclear pre-replicative complex Gene Set From GO Cellular Component Annotations 2015 proteins localized to the nuclear pre-replicative complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.
pre-replicative complex Gene Set From GO Cellular Component Annotations 2015 proteins localized to the pre-replicative complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.
Activation of the pre-replicative complex Gene Set From Reactome Pathways 2014 proteins participating in the Activation of the pre-replicative complex pathway from the Reactome Pathways dataset.
Assembly of the pre-replicative complex Gene Set From Reactome Pathways 2014 proteins participating in the Assembly of the pre-replicative complex pathway from the Reactome Pathways dataset.
Association of licensing factors with the pre-replicative complex Gene Set From Reactome Pathways 2014 proteins participating in the Association of licensing factors with the pre-replicative complex pathway from the Reactome Pathways dataset.
Switching of origins to a post-replicative state Gene Set From Reactome Pathways 2014 proteins participating in the Switching of origins to a post-replicative state pathway from the Reactome Pathways dataset.
non-replicative DNA transposition Gene Set From GO Biological Process Annotations 2023 genes participating in the non-replicative DNA transposition biological process from the curated GO Biological Process Annotations 2023 dataset.
Activation of the pre-replicative complex Gene Set From Reactome Pathways 2024 proteins participating in the Activation of the pre-replicative complex pathway from the Reactome Pathways 2024 dataset.
Assembly of the pre-replicative complex Gene Set From Reactome Pathways 2024 proteins participating in the Assembly of the pre-replicative complex pathway from the Reactome Pathways 2024 dataset.
Switching of origins to a post-replicative state Gene Set From Reactome Pathways 2024 proteins participating in the Switching of origins to a post-replicative state pathway from the Reactome Pathways 2024 dataset.
non-replicative DNA transposition Gene Set From GO Biological Process Annotations 2025 genes participating in the non-replicative DNA transposition biological process from the curated GO Biological Process Annotations 2025 dataset.
Nuclear pre-replicative complex Gene Set From COMPARTMENTS Curated Protein Localization Evidence Scores 2025 proteins localized to the Nuclear pre-replicative complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
pre-replicative complex Gene Set From COMPARTMENTS Curated Protein Localization Evidence Scores 2025 proteins localized to the pre-replicative complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
pre-replicative complex Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the pre-replicative complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
Nuclear pre-replicative complex Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Nuclear pre-replicative complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
Bacterial pre-replicative complex Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Bacterial pre-replicative complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
senescence-associated heterochromatin focus Gene Set From COMPARTMENTS Curated Protein Localization Evidence Scores proteins localized to the senescence-associated heterochromatin focus cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.
senescence-associated heterochromatin focus Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the senescence-associated heterochromatin focus cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.
senescence Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term senescence in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
regulation of cellular senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
oncogene-induced cell senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the oncogene-induced cell senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
senescence-associated heterochromatin focus assembly Gene Set From GO Biological Process Annotations 2015 genes participating in the senescence-associated heterochromatin focus assembly biological process from the curated GO Biological Process Annotations 2015 dataset.
cellular senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the cellular senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
stress-induced premature senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the stress-induced premature senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
negative regulation of cellular senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the negative regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
oxidative stress-induced premature senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the oxidative stress-induced premature senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
organ senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the organ senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of cellular senescence Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2015 dataset.
senescence-associated heterochromatin focus Gene Set From GO Cellular Component Annotations 2015 proteins localized to the senescence-associated heterochromatin focus cellular component from the curated GO Cellular Component Annotations 2015 dataset.
Senescence/spartin-associated Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Senescence/spartin-associated protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Senescence marker protein-30 (SMP-30) Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Senescence marker protein-30 (SMP-30) protein domain from the InterPro Predicted Protein Domain Annotations dataset.
early reproductive senescence Gene Set From MPO Gene-Phenotype Associations gene mutations causing the early reproductive senescence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
senescence Gene Set From Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term senescence in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.
DNA Damage/Telomere Stress Induced Senescence Gene Set From Reactome Pathways 2014 proteins participating in the DNA Damage/Telomere Stress Induced Senescence pathway from the Reactome Pathways dataset.
Formation of Senescence-Associated Heterochromatin Foci (SAHF) Gene Set From Reactome Pathways 2014 proteins participating in the Formation of Senescence-Associated Heterochromatin Foci (SAHF) pathway from the Reactome Pathways dataset.
Senescence-Associated Secretory Phenotype (SASP) Gene Set From Reactome Pathways 2014 proteins participating in the Senescence-Associated Secretory Phenotype (SASP) pathway from the Reactome Pathways dataset.
Oncogene Induced Senescence Gene Set From Reactome Pathways 2014 proteins participating in the Oncogene Induced Senescence pathway from the Reactome Pathways dataset.
Cellular Senescence Gene Set From Reactome Pathways 2014 proteins participating in the Cellular Senescence pathway from the Reactome Pathways dataset.
Oxidative Stress Induced Senescence Gene Set From Reactome Pathways 2014 proteins participating in the Oxidative Stress Induced Senescence pathway from the Reactome Pathways dataset.
Senescence and Autophagy(Homo sapiens) Gene Set From WikiPathways Pathways 2014 proteins participating in the Senescence and Autophagy(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.
oxidative stress-induced premature senescence Gene Set From GO Biological Process Annotations 2023 genes participating in the oxidative stress-induced premature senescence biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of cellular senescence Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2023 dataset.
negative regulation of cellular senescence Gene Set From GO Biological Process Annotations 2023 genes participating in the negative regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of cellular senescence Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2023 dataset.
oncogene-induced cell senescence Gene Set From GO Biological Process Annotations 2023 genes participating in the oncogene-induced cell senescence biological process from the curated GO Biological Process Annotations 2023 dataset.
stress-induced premature senescence Gene Set From GO Biological Process Annotations 2023 genes participating in the stress-induced premature senescence biological process from the curated GO Biological Process Annotations 2023 dataset.
senescence-associated heterochromatin focus Gene Set From GO Cellular Component Annotations 2023 proteins localized to the senescence-associated heterochromatin focus cellular component from the curated GO Cellular Component Annotations 2023 dataset.
early reproductive senescence Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the early reproductive senescence phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
delayed reproductive senescence Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the delayed reproductive senescence phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
Senescence associated secretory phenotype SASP Gene Set From WikiPathways Pathways 2024 proteins participating in the Senescence associated secretory phenotype SASP pathway from the WikiPathways Pathways 2024 dataset.
Kynurenine pathway and links to cell senescence Gene Set From WikiPathways Pathways 2024 proteins participating in the Kynurenine pathway and links to cell senescence pathway from the WikiPathways Pathways 2024 dataset.
Glycolysis in senescence Gene Set From WikiPathways Pathways 2024 proteins participating in the Glycolysis in senescence pathway from the WikiPathways Pathways 2024 dataset.
TCA cycle in senescence Gene Set From WikiPathways Pathways 2024 proteins participating in the TCA cycle in senescence pathway from the WikiPathways Pathways 2024 dataset.
Sphingolipid metabolism in senescence Gene Set From WikiPathways Pathways 2024 proteins participating in the Sphingolipid metabolism in senescence pathway from the WikiPathways Pathways 2024 dataset.
Prostaglandin and leukotriene metabolism in senescence Gene Set From WikiPathways Pathways 2024 proteins participating in the Prostaglandin and leukotriene metabolism in senescence pathway from the WikiPathways Pathways 2024 dataset.
COVID 19 and endothelial cell senescence Gene Set From WikiPathways Pathways 2024 proteins participating in the COVID 19 and endothelial cell senescence pathway from the WikiPathways Pathways 2024 dataset.
Omega 6 fatty acids in senescence Gene Set From WikiPathways Pathways 2024 proteins participating in the Omega 6 fatty acids in senescence pathway from the WikiPathways Pathways 2024 dataset.
Cellular Senescence Gene Set From Reactome Pathways 2024 proteins participating in the Cellular Senescence pathway from the Reactome Pathways 2024 dataset.
DNA Damage/Telomere Stress Induced Senescence Gene Set From Reactome Pathways 2024 proteins participating in the DNA Damage/Telomere Stress Induced Senescence pathway from the Reactome Pathways 2024 dataset.
Diseases of Cellular Senescence Gene Set From Reactome Pathways 2024 proteins participating in the Diseases of Cellular Senescence pathway from the Reactome Pathways 2024 dataset.
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 Gene Set From Reactome Pathways 2024 proteins participating in the Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 pathway from the Reactome Pathways 2024 dataset.
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 Gene Set From Reactome Pathways 2024 proteins participating in the Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 pathway from the Reactome Pathways 2024 dataset.
Evasion of Oncogene Induced Senescence Due to p14ARF Defects Gene Set From Reactome Pathways 2024 proteins participating in the Evasion of Oncogene Induced Senescence Due to p14ARF Defects pathway from the Reactome Pathways 2024 dataset.
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects Gene Set From Reactome Pathways 2024 proteins participating in the Evasion of Oncogene Induced Senescence Due to p16INK4A Defects pathway from the Reactome Pathways 2024 dataset.
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 Gene Set From Reactome Pathways 2024 proteins participating in the Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 pathway from the Reactome Pathways 2024 dataset.
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 Gene Set From Reactome Pathways 2024 proteins participating in the Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 pathway from the Reactome Pathways 2024 dataset.
Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects Gene Set From Reactome Pathways 2024 proteins participating in the Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects pathway from the Reactome Pathways 2024 dataset.
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects Gene Set From Reactome Pathways 2024 proteins participating in the Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects pathway from the Reactome Pathways 2024 dataset.
Formation of Senescence-Associated Heterochromatin Foci (SAHF) Gene Set From Reactome Pathways 2024 proteins participating in the Formation of Senescence-Associated Heterochromatin Foci (SAHF) pathway from the Reactome Pathways 2024 dataset.
Oncogene Induced Senescence Gene Set From Reactome Pathways 2024 proteins participating in the Oncogene Induced Senescence pathway from the Reactome Pathways 2024 dataset.
Oxidative Stress Induced Senescence Gene Set From Reactome Pathways 2024 proteins participating in the Oxidative Stress Induced Senescence pathway from the Reactome Pathways 2024 dataset.
Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence Gene Set From Reactome Pathways 2024 proteins participating in the Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence pathway from the Reactome Pathways 2024 dataset.
Senescence-Associated Secretory Phenotype (SASP) Gene Set From Reactome Pathways 2024 proteins participating in the Senescence-Associated Secretory Phenotype (SASP) pathway from the Reactome Pathways 2024 dataset.
oxidative stress-induced premature senescence Gene Set From GO Biological Process Annotations 2025 genes participating in the oxidative stress-induced premature senescence biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of cellular senescence Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2025 dataset.
negative regulation of cellular senescence Gene Set From GO Biological Process Annotations 2025 genes participating in the negative regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2025 dataset.
positive regulation of cellular senescence Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of cellular senescence biological process from the curated GO Biological Process Annotations 2025 dataset.
senescence-associated heterochromatin focus Gene Set From GO Cellular Component Annotations 2025 proteins localized to the senescence-associated heterochromatin focus cellular component from the curated GO Cellular Component Annotations 2025 dataset.
senescence-associated heterochromatin focus Gene Set From COMPARTMENTS Curated Protein Localization Evidence Scores 2025 proteins localized to the senescence-associated heterochromatin focus cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.
senescence-associated heterochromatin focus Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the senescence-associated heterochromatin focus cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
senescence-associated vacuole Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the senescence-associated vacuole cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
Cellular senescence Gene Set From KEGG Pathways 2026 proteins participating in the Cellular senescence pathway from the KEGG Pathways 2026 dataset.

Harmonizome 3.0

replicative senescence Gene Set

abnormal cellular replicative senescence Gene Set

early cellular replicative senescence Gene Set

delayed cellular replicative senescence Gene Set

delayed cellular replicative senescence Gene Set

early cellular replicative senescence Gene Set

abnormal cellular replicative senescence Gene Set

NAD metabolism in oncogene induced senescence and mitochondrial dysfunction associated senescence Gene Set

nuclear pre-replicative complex Gene Set

pre-replicative complex Gene Set

replicative Gene Set

pre-replicative complex assembly involved in cell cycle dna replication Gene Set

regulation of replicative cell aging Gene Set

replicative cell aging Gene Set

pre-replicative complex assembly involved in nuclear cell cycle dna replication Gene Set

pre-replicative complex assembly Gene Set

nuclear pre-replicative complex Gene Set

pre-replicative complex Gene Set

Activation of the pre-replicative complex Gene Set

Assembly of the pre-replicative complex Gene Set

Association of licensing factors with the pre-replicative complex Gene Set

Switching of origins to a post-replicative state Gene Set

non-replicative DNA transposition Gene Set

Activation of the pre-replicative complex Gene Set

Assembly of the pre-replicative complex Gene Set

Switching of origins to a post-replicative state Gene Set

non-replicative DNA transposition Gene Set

Nuclear pre-replicative complex Gene Set

pre-replicative complex Gene Set

pre-replicative complex Gene Set

Nuclear pre-replicative complex Gene Set

Bacterial pre-replicative complex Gene Set

senescence-associated heterochromatin focus Gene Set

senescence-associated heterochromatin focus Gene Set

senescence Gene Set

regulation of cellular senescence Gene Set

oncogene-induced cell senescence Gene Set

senescence-associated heterochromatin focus assembly Gene Set

cellular senescence Gene Set

stress-induced premature senescence Gene Set

negative regulation of cellular senescence Gene Set

oxidative stress-induced premature senescence Gene Set

organ senescence Gene Set

positive regulation of cellular senescence Gene Set

senescence-associated heterochromatin focus Gene Set

Senescence/spartin-associated Gene Set

Senescence marker protein-30 (SMP-30) Gene Set

early reproductive senescence Gene Set

senescence Gene Set

DNA Damage/Telomere Stress Induced Senescence Gene Set

Formation of Senescence-Associated Heterochromatin Foci (SAHF) Gene Set

Senescence-Associated Secretory Phenotype (SASP) Gene Set

Oncogene Induced Senescence Gene Set

Cellular Senescence Gene Set

Oxidative Stress Induced Senescence Gene Set

Senescence and Autophagy(Homo sapiens) Gene Set

oxidative stress-induced premature senescence Gene Set

regulation of cellular senescence Gene Set

negative regulation of cellular senescence Gene Set

positive regulation of cellular senescence Gene Set

oncogene-induced cell senescence Gene Set

stress-induced premature senescence Gene Set

senescence-associated heterochromatin focus Gene Set

early reproductive senescence Gene Set

delayed reproductive senescence Gene Set

Senescence associated secretory phenotype SASP Gene Set

Kynurenine pathway and links to cell senescence Gene Set

Glycolysis in senescence Gene Set

TCA cycle in senescence Gene Set

Sphingolipid metabolism in senescence Gene Set

Prostaglandin and leukotriene metabolism in senescence Gene Set

COVID 19 and endothelial cell senescence Gene Set

Omega 6 fatty acids in senescence Gene Set

Cellular Senescence Gene Set

DNA Damage/Telomere Stress Induced Senescence Gene Set

Diseases of Cellular Senescence Gene Set

Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 Gene Set

Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6 Gene Set

Evasion of Oncogene Induced Senescence Due to p14ARF Defects Gene Set