Name

SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs Dataset

From SILAC Phosphoproteomics

Phosphorylation levels of proteins in cell lines following drug treatment

SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Gene Perturbations Dataset

From SILAC Phosphoproteomics

Phosphorylation levels of proteins in cell lines following genetic perturbation (knockdown, knockout, over-expression, mutation)

SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands Dataset

From SILAC Phosphoproteomics

Phosphorylation levels of proteins in cell lines following ligand treatment

CTNNB1 Gene

catenin (cadherin-associated protein), beta 1, 88kDa

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

MRPS33P1 Gene

mitochondrial ribosomal protein S33 pseudogene 1

MRPS33P2 Gene

mitochondrial ribosomal protein S33 pseudogene 2

MRPS33P3 Gene

mitochondrial ribosomal protein S33 pseudogene 3

MRPS33P4 Gene

mitochondrial ribosomal protein S33 pseudogene 4

MRPS33 Gene

mitochondrial ribosomal protein S33

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q [provided by RefSeq, Jul 2008]

CTNNB1 S33 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S33 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

S33 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S33 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

CTNNB1 S37 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S37 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

CTNNB1 S45 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S45 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

CTNNB1 T41 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 T41 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

S37 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S37 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

S45 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S45 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

T41 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the T41 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants pathway from the Reactome Pathways 2024 dataset.

phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex pathway from the Reactome Pathways dataset.

Signaling by CTNNB1 phospho-site mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by CTNNB1 phospho-site mutants pathway from the Reactome Pathways 2024 dataset.

s33 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term s33 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Ribosomal protein S27/S33, mitochondrial Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribosomal protein S27/S33, mitochondrial protein domain from the InterPro Predicted Protein Domain Annotations dataset.

phosphorylated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term phosphorylated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

phosphorylated carbohydrate dephosphorylation Gene Set

From GO Biological Process Annotations 2015

genes participating in the phosphorylated carbohydrate dephosphorylation biological process from the curated GO Biological Process Annotations 2015 dataset.

protein phosphorylated amino acid binding Gene Set

From GO Molecular Function Annotations 2015

genes performing the protein phosphorylated amino acid binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

serine biosynthesis (phosphorylated route) Gene Set

From HumanCyc Pathways

proteins participating in the serine biosynthesis (phosphorylated route) pathway from the HumanCyc Pathways dataset.

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter, C-terminal domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter, C-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Phosphorylated adapter RNA export protein, RNA-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphorylated adapter RNA export protein, RNA-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Phosphorylated CTD interacting factor 1, WW domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphorylated CTD interacting factor 1, WW domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Phosphorylated immunoreceptor signalling ITAM Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphorylated immunoreceptor signalling ITAM protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1/2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1/2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

tyrosine-phosphorylated Gene Set

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term tyrosine-phosphorylated in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Gene Set

From Reactome Pathways 2014

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways dataset.

protein phosphorylated amino acid binding Gene Set

From GO Molecular Function Annotations 2023

genes performing the protein phosphorylated amino acid binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

phosphorylated histone binding Gene Set

From GO Molecular Function Annotations 2023

genes performing the phosphorylated histone binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Gene Set

From Reactome Pathways 2024

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways 2024 dataset.

protein phosphorylated amino acid binding Gene Set

From GO Molecular Function Annotations 2025

genes performing the protein phosphorylated amino acid binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

CTNNB1-24651522-LGR5+ INTESTINAL STEM CELL-HUMAN Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the CTNNB1-24651522-LGR5+ INTESTINAL STEM CELL-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

CTNNB1-20460455-HCT116-HUMAN Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the CTNNB1-20460455-HCT116-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

CTNNB1-20615089-FETAL_BRAIN-HUMAN Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the CTNNB1-20615089-FETAL_BRAIN-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

CTNNB1 Gene Set

From ChEA Transcription Factor Targets

target genes of the CTNNB1 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

TCF4-CTNNB1-EP300 complex Gene Set

From CORUM Protein Complexes

proteins in the TCF4-CTNNB1-EP300 complex protein complex from the CORUM Protein Complexes dataset.

Polycystin-1 multiprotein complex (ACTN1, CDH1, SRC, JUP, VCL, CTNNB1, PXN, BCAR1, PKD1, PTK2, TLN1) Gene Set

From CORUM Protein Complexes

proteins in the Polycystin-1 multiprotein complex (ACTN1, CDH1, SRC, JUP, VCL, CTNNB1, PXN, BCAR1, PKD1, PTK2, TLN1) protein complex from the CORUM Protein Complexes dataset.

Axin2-Ctnnb1-Apc complex Gene Set

From CORUM Protein Complexes

proteins in the Axin2-Ctnnb1-Apc complex protein complex from the CORUM Protein Complexes dataset.

TCF4-CTNNB1-CREBBP complex Gene Set

From CORUM Protein Complexes

proteins in the TCF4-CTNNB1-CREBBP complex protein complex from the CORUM Protein Complexes dataset.

TCF4-CTNNB1-SUMO1-EP300-HADAC6 complex Gene Set

From CORUM Protein Complexes

proteins in the TCF4-CTNNB1-SUMO1-EP300-HADAC6 complex protein complex from the CORUM Protein Complexes dataset.

Bipartite complex (TFC4, CTNNB1) Gene Set

From CORUM Protein Complexes

proteins in the Bipartite complex (TFC4, CTNNB1) protein complex from the CORUM Protein Complexes dataset.

Lef1-Tle1-Ctnnb1 complex Gene Set

From CORUM Protein Complexes

proteins in the Lef1-Tle1-Ctnnb1 complex protein complex from the CORUM Protein Complexes dataset.

TCF4-CTNNB1 complex Gene Set

From CORUM Protein Complexes

proteins in the TCF4-CTNNB1 complex protein complex from the CORUM Protein Complexes dataset.

JUN-TCF4-CTNNB1 complex Gene Set

From CORUM Protein Complexes

proteins in the JUN-TCF4-CTNNB1 complex protein complex from the CORUM Protein Complexes dataset.

Xin-Cdh2-Ctnnb1-Ctnnd1 complex Gene Set

From CORUM Protein Complexes

proteins in the Xin-Cdh2-Ctnnb1-Ctnnd1 complex protein complex from the CORUM Protein Complexes dataset.

Cell-cell junction complex (CDH1-CTNNB1) Gene Set

From CORUM Protein Complexes

proteins in the Cell-cell junction complex (CDH1-CTNNB1) protein complex from the CORUM Protein Complexes dataset.

ctnnb1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ctnnb1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CTNNB1 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein CTNNB1 from the curated Hub Proteins Protein-Protein Interactions dataset.

CTNNB1 binding, N-teminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CTNNB1 binding, N-teminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

CTNNB1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CTNNB1 from the Pathway Commons Protein-Protein Interactions dataset.

binding of TCF/LEF:CTNNB1 to target gene promoters Gene Set

From Reactome Pathways 2014

proteins participating in the binding of TCF/LEF:CTNNB1 to target gene promoters pathway from the Reactome Pathways dataset.

CTNNB1-24651522-LGR5+-INTESTINAL-STEM-HUMAN Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the CTNNB1-24651522-LGR5+-INTESTINAL-STEM-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

CTNNB1-20615089-FETAL-BRAIN-HUMAN Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the CTNNB1-20615089-FETAL-BRAIN-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

CTNNB1-20460455-HCT116-HUMAN Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the CTNNB1-20460455-HCT116-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

CTNNB1 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the CTNNB1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

Binding of TCF/LEF:CTNNB1 to target gene promoters Gene Set

From Reactome Pathways 2024

proteins participating in the Binding of TCF/LEF:CTNNB1 to target gene promoters pathway from the Reactome Pathways 2024 dataset.

CTNNB1 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the CTNNB1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

mutants Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mutants in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways dataset.

SMAD2/3 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways dataset.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

AXIN missense mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR3 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR3 mutants pathway from the Reactome Pathways dataset.

APC truncation mutants have impaired AXIN binding Gene Set

From Reactome Pathways 2014

proteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways dataset.

APC truncation mutants are not K63 polyubiquitinated Gene Set

From Reactome Pathways 2014

proteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways dataset.

Signaling by FGFR2 amplification mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways dataset.

FBXW7 Mutants and NOTCH1 in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways dataset.

Signaling by FGFR1 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR1 fusion mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 fusion mutants pathway from the Reactome Pathways dataset.

TCF7L2 mutants don't bind CTBP Gene Set

From Reactome Pathways 2014

proteins participating in the TCF7L2 mutants don't bind CTBP pathway from the Reactome Pathways dataset.

Signaling by FGFR2 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR2 mutants pathway from the Reactome Pathways dataset.

RNF mutants show enhanced WNT signaling and proliferation Gene Set

From Reactome Pathways 2014

proteins participating in the RNF mutants show enhanced WNT signaling and proliferation pathway from the Reactome Pathways dataset.

Signaling by FGFR4 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR4 mutants pathway from the Reactome Pathways dataset.

Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

truncated APC mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the truncated APC mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

AXIN mutants destabilize the destruction complex, activating WNT signaling Gene Set

From Reactome Pathways 2014

proteins participating in the AXIN mutants destabilize the destruction complex, activating WNT signaling pathway from the Reactome Pathways dataset.

Activated point mutants of FGFR2 Gene Set

From Reactome Pathways 2014

proteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways dataset.

TGFBR2 Kinase Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by FGFR mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR1 amplification mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways dataset.

AMER1 mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the AMER1 mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling Gene Set

From Reactome Pathways 2014

proteins participating in the misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway from the Reactome Pathways dataset.

SMAD4 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

TGFBR2 MSI Frameshift Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by activated point mutants of FGFR1 Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways dataset.

Signaling by activated point mutants of FGFR3 Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways dataset.

misspliced GSK3beta mutants stabilize beta-catenin Gene Set

From Reactome Pathways 2014

proteins participating in the misspliced GSK3beta mutants stabilize beta-catenin pathway from the Reactome Pathways dataset.

ALK mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the ALK mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

APC truncation mutants are not K63 polyubiquitinated Gene Set

From Reactome Pathways 2024

proteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways 2024 dataset.

APC truncation mutants have impaired AXIN binding Gene Set

From Reactome Pathways 2024

proteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways 2024 dataset.

ASP-3026-resistant ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the ASP-3026-resistant ALK mutants pathway from the Reactome Pathways 2024 dataset.

AXIN missense mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2024

proteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways 2024 dataset.

Activated point mutants of FGFR2 Gene Set

From Reactome Pathways 2024

proteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Dasatinib-resistant KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Dasatinib-resistant KIT mutants pathway from the Reactome Pathways 2024 dataset.

Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Gene Set

From Reactome Pathways 2024

proteins participating in the Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) pathway from the Reactome Pathways 2024 dataset.

Defective translocation of RB1 mutants to the nucleus Gene Set

From Reactome Pathways 2024

proteins participating in the Defective translocation of RB1 mutants to the nucleus pathway from the Reactome Pathways 2024 dataset.

Drug resistance in ERBB2 KD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance in ERBB2 KD mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance in ERBB2 TMD/JMD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance in ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of ALK mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of KIT mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of PDGFR mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of PDGFR mutants pathway from the Reactome Pathways 2024 dataset.

FBXW7 Mutants and NOTCH1 in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways 2024 dataset.

FLT3 mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling by CBL mutants Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling by CBL mutants pathway from the Reactome Pathways 2024 dataset.

Hh mutants abrogate ligand secretion Gene Set

From Reactome Pathways 2024

proteins participating in the Hh mutants abrogate ligand secretion pathway from the Reactome Pathways 2024 dataset.

Hh mutants are degraded by ERAD Gene Set

From Reactome Pathways 2024

proteins participating in the Hh mutants are degraded by ERAD pathway from the Reactome Pathways 2024 dataset.

Imatinib-resistant KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Imatinib-resistant KIT mutants pathway from the Reactome Pathways 2024 dataset.

Imatinib-resistant PDGFR mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Imatinib-resistant PDGFR mutants pathway from the Reactome Pathways 2024 dataset.

KIT mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the KIT mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

KW2449-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the KW2449-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

Masitinib-resistant KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Masitinib-resistant KIT mutants pathway from the Reactome Pathways 2024 dataset.

NVP-TAE684-resistant ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the NVP-TAE684-resistant ALK mutants pathway from the Reactome Pathways 2024 dataset.

Nilotinib-resistant KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Nilotinib-resistant KIT mutants pathway from the Reactome Pathways 2024 dataset.

PDGFR mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the PDGFR mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

RAS GTPase cycle mutants Gene Set

From Reactome Pathways 2024

proteins participating in the RAS GTPase cycle mutants pathway from the Reactome Pathways 2024 dataset.

Regorafenib-resistant KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Regorafenib-resistant KIT mutants pathway from the Reactome Pathways 2024 dataset.

Regorafenib-resistant PDGFR mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Regorafenib-resistant PDGFR mutants pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to AEE788 Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to AEE788 pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to afatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to afatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to lapatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to lapatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to neratinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to neratinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to osimertinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to osimertinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to sapitinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to sapitinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to tesevatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to tesevatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to trastuzumab Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to trastuzumab pathway from the Reactome Pathways 2024 dataset.

SMAD2/3 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

SMAD4 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

STAT5 activation downstream of FLT3 ITD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the STAT5 activation downstream of FLT3 ITD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ALK fusions and activated point mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ALK fusions and activated point mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by AMER1 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by AMER1 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by APC mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by APC mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by AXIN mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by AXIN mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 ECD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 ECD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 KD Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 KD Mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 TMD/JMD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FGFR1 amplification mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FGFR2 amplification mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FLT3 ITD and TKD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FLT3 ITD and TKD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by GSK3beta mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by GSK3beta mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by LRP5 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by LRP5 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MAP2K mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MAP2K mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MAPK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MAPK mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MRAS-complex mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MRAS-complex mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by PDGFRA extracellular domain mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by PDGFRA extracellular domain mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAF1 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAF1 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS GAP mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS GAP mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS GTPase mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS GTPase mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RNF43 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RNF43 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by TCF7L2 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by TCF7L2 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by activated point mutants of FGFR1 Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways 2024 dataset.

Signaling by activated point mutants of FGFR3 Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways 2024 dataset.

Signaling by cytosolic FGFR1 fusion mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by cytosolic FGFR1 fusion mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by extracellular domain mutants of KIT Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by extracellular domain mutants of KIT pathway from the Reactome Pathways 2024 dataset.

Signaling by high-kinase activity BRAF mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by high-kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by juxtamembrane domain KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by juxtamembrane domain KIT mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by kinase domain mutants of KIT Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by kinase domain mutants of KIT pathway from the Reactome Pathways 2024 dataset.

Signaling by moderate kinase activity BRAF mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by moderate kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset.

Signaling downstream of RAS mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling downstream of RAS mutants pathway from the Reactome Pathways 2024 dataset.

Sorafenib-resistant KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Sorafenib-resistant KIT mutants pathway from the Reactome Pathways 2024 dataset.

Sorafenib-resistant PDGFR mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Sorafenib-resistant PDGFR mutants pathway from the Reactome Pathways 2024 dataset.

Sunitinib-resistant KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Sunitinib-resistant KIT mutants pathway from the Reactome Pathways 2024 dataset.

Sunitinib-resistant PDGFR mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Sunitinib-resistant PDGFR mutants pathway from the Reactome Pathways 2024 dataset.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR2 Kinase Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR2 MSI Frameshift Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

alectinib-resistant ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the alectinib-resistant ALK mutants pathway from the Reactome Pathways 2024 dataset.

brigatinib-resistant ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the brigatinib-resistant ALK mutants pathway from the Reactome Pathways 2024 dataset.

ceritinib-resistant ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the ceritinib-resistant ALK mutants pathway from the Reactome Pathways 2024 dataset.

crenolanib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the crenolanib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

crizotinib-resistant ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the crizotinib-resistant ALK mutants pathway from the Reactome Pathways 2024 dataset.

gilteritinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the gilteritinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

lestaurtinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the lestaurtinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

linifanib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the linifanib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

lorlatinib-resistant ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the lorlatinib-resistant ALK mutants pathway from the Reactome Pathways 2024 dataset.

midostaurin-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the midostaurin-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

pexidartinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the pexidartinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

ponatinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the ponatinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

quizartinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the quizartinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

semaxanib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the semaxanib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

sorafenib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the sorafenib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

sunitinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the sunitinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

tamatinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the tamatinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

tandutinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the tandutinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.