Harmonizome 3.0

opioid growth factor receptor

The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]

opioid receptor, kappa 1

This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

opioid growth factor receptor-like 1

Predicted to enable opioid growth factor receptor activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

opioid growth factor receptor pseudogene

sigma non-opioid intracellular receptor 1

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013]

opioid receptor, delta 1

Enables G protein-coupled enkephalin receptor activity. Involved in several processes, including G protein-coupled opioid receptor signaling pathway; cellular response to hypoxia; and positive regulation of peptidyl-serine phosphorylation. Located in plasma membrane. Implicated in alcohol dependence; alcohol use disorder; drug dependence (multiple); opioid abuse; and withdrawal disorder. Biomarker of opioid abuse. [provided by Alliance of Genome Resources, Mar 2025]

Opioid dependence, susceptibility to, 1

opioid binding protein/cell adhesion molecule-like

This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. The encoded preprotein is proteolytically processed to generate the mature protein. This protein is localized in the plasma membrane and may have an accessory role in opioid receptor function. This gene has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the encoded protein is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

opioid growth factor receptor pseudogene 1

opioid receptor, mu 1

This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]

From Reactome Pathways 2014

proteins participating in the Opioid Signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2024

proteins participating in the Opioid Signalling pathway from the Reactome Pathways 2024 dataset.

From CTD Gene-Disease Associations

genes/proteins associated with the disease Opioid-Related Disorders from the curated CTD Gene-Disease Associations dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores

genes co-occuring with the disease opioid abuse in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

From GAD Gene-Disease Associations

genes associated with the disease opioid abuse in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease apnea; opioid-related disorders; pain in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alcoholism; opioid-related disorders; substance-related disorders in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease opioid-related disorders; tobacco use disorder in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease opioid-related disorders in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease opioid-related disorders; substance withdrawal syndrome in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease pain tolerance, and opioid addiction in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cocaine-related disorders; opioid-related disorders; substance-related disorders in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease opioid drug (tramadol) metabolite ratios in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cortisol response to opioid blockade in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease acth, rate of decrease; acth, rate of increase; cortisol response to opioid receptor blockade in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease opioid-related disorders; pain in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease opioid dependence in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term opioid in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the adenylate cyclase-inhibiting opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the mu-type opioid receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the kappa-type opioid receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the opioid peptide activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the opioid receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the opioid receptor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Opioid sensitivity phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Opioid-Related Disorders phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Kappa opioid receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Opioid receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Opioid neuropeptide precursor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Opioid growth factor receptor (OGFr) conserved domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the X opioid receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sigma non-opioid intracellular receptor 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Opioid growth factor receptor repeat protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Delta opioid receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mu opioid receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From OMIM Gene-Disease Associations

genes associated with the {opioid dependence, susceptibility to} phenotype from the curated OMIM Gene-Disease Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the {opioid dependence, susceptibility to, 1} phenotype from the curated OMIM Gene-Disease Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the [analgesia from kappa-opioid receptor agonist, female-specific] phenotype from the curated OMIM Gene-Disease Associations dataset.

From PANTHER Pathways

proteins participating in the Opioid proopiomelanocortin pathway pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Opioid proenkephalin pathway pathway from the PANTHER Pathways dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Opioid Use Disorder in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Opioid Use in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Opioid Abuse in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Opioid Withdrawal in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Opioid Abuse And Addiction in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Increased Analgesia From Kappa-Opioid Receptor Agonist, Female-Specific (Disorder) in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Opioid Use Disorder, Severe in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Opioid-Induced Constipation in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Opioid Overdose in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the G protein-coupled opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the adenylate cyclase-inhibiting opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the G protein-coupled opioid receptor activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the opioid receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the mu-type opioid receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From WikiPathways Pathways 2024

proteins participating in the Opioid receptor pathways pathway from the WikiPathways Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the G protein-coupled opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the adenylate cyclase-inhibiting opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the opioid peptide activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the opioid receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the G protein-coupled opioid receptor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the mu-type opioid receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occuring with the disease Opioid abuse in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Increased analgesia from kappa-opioid receptor agonist phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Opioid exposure phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Methadone dose in opioid dependence phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Opioid dependence phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Opioid use cessation phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Opioid use disorder phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Opioid overdose severity score phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Opioid sensitivity phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Response to opioid analgesics in cancer (pain decrease) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Opioid requirements during laparoscopic-assisted colectomy phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Opioid dependence (time to event) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From Biocarta Pathways

proteins participating in the phospholipids as signalling intermediaries pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the wnt lrp6 signalling pathway from the Biocarta Pathways dataset.

From CORUM Protein Complexes

proteins in the P2X7 receptor signalling complex protein complex from the CORUM Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term signalling in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From HumanCyc Pathways

proteins participating in the BMP Signalling Pathway pathway from the HumanCyc Pathways dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Suppressor of cytokine signalling protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NO signalling/Golgi transport ligand-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Suppressor of cytokine signalling 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Suppressor of cytokine signalling 7 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Suppressor of cytokine signalling 4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Suppressor of cytokine signalling 5 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Suppressor of cytokine signalling 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Suppressor of cytokine signalling 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Suppressor of cytokine signalling 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the G-protein-signalling modulator 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the G-protein-signalling modulator 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Regulator of G-protein signalling 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CD3 signalling complex delta subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hedgehog, N-terminal signalling domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Regulator of G protein signalling-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the SRC kinase signalling inhibitor 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Signalling lymphocyte activation molecule family receptors protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphorylated immunoreceptor signalling ITAM protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Hedgehog signalling/DD-peptidase zinc-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mitochondrial antiviral-signalling protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Regulator of G-protein signalling 9-binding protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From PANTHER Pathways

proteins participating in the Integrin signalling pathway pathway from the PANTHER Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Cell death signalling via NRAGE, NRIF and NADE pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the G beta:gamma signalling through PLC beta pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Retrograde neurotrophin signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Thromboxane signalling through TP receptor pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the PLC-gamma1 signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Ceramide signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Activated TLR4 signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the IRS-mediated signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Death Receptor Signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Signalling to RAS pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the G beta:gamma signalling through PI3Kgamma pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Prostacyclin signalling through prostacyclin receptor pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the mTOR signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the SOS-mediated signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the G alpha (12/13) signalling events pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Thrombin signalling through proteinase activated receptors (PARs) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Signalling by NGF pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the p75 NTR receptor-mediated signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the PDE3B signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the GP1b-IX-V activation signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Signalling to ERKs pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the p75NTR recruits signalling complexes pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Signalling to ERK5 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the S6K1 signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the G alpha (z) signalling events pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Rap1 signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the ADP signalling through P2Y purinoceptor 12 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Signalling to STAT3 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the NGF signalling via TRKA from the plasma membrane pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the G alpha (s) signalling events pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the ADP signalling through P2Y purinoceptor 1 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Gastrin-CREB signalling pathway via PKC and MAPK pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Insulin receptor signalling cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the G alpha (i) signalling events pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the NADE modulates death signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the SHC-mediated signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the S6K1-mediated signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Signalling to p38 via RIT and RIN pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the G-protein beta:gamma signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Adrenaline signalling through Alpha-2 adrenergic receptor pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the mTORC1-mediated signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the G alpha (q) signalling events pathway from the Reactome Pathways dataset.

From WikiPathways Pathways 2014

proteins participating in the SREBP signalling(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Estrogen signalling(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the BMP Signalling and Regulation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From SynGO Synaptic Gene Annotations

genes associated with the synaptic term trans-synaptic signalling via exosome from the SynGO Synaptic Gene Annotations dataset.

From Reactome Pathways 2024

proteins participating in the ADP signalling through P2Y purinoceptor 1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the ADP signalling through P2Y purinoceptor 12 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Adrenaline signalling through Alpha-2 adrenergic receptor pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Aryl hydrocarbon receptor signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Caspase activation via extrinsic apoptotic signalling pathway pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Cell death signalling via NRAGE, NRIF and NADE pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Ceramide signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G alpha (12/13) signalling events pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G alpha (i) signalling events pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G alpha (q) signalling events pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G alpha (s) signalling events pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G alpha (z) signalling events pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G beta:gamma signalling through BTK pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G beta:gamma signalling through CDC42 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G beta:gamma signalling through PI3Kgamma pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G beta:gamma signalling through PLC beta pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the G-protein beta:gamma signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the GP1b-IX-V activation signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the GPCR downstream signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Gastrin-CREB signalling pathway via PKC and MAPK pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the IRS-mediated signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Insulin receptor signalling cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Interleukin-35 Signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the MTOR signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the NADE modulates death signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the PDE3B signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the PLC-gamma1 signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Prostacyclin signalling through prostacyclin receptor pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Rap1 signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Reelin signalling pathway pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Retrograde neurotrophin signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SARS-CoV-1 targets host intracellular signalling and regulatory pathways pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SARS-CoV-2 targets host intracellular signalling and regulatory pathways pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SOS-mediated signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Signalling to ERK5 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Signalling to ERKs pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Signalling to RAS pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Signalling to STAT3 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Signalling to p38 via RIT and RIN pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Thrombin signalling through proteinase activated receptors (PARs) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Thromboxane signalling through TP receptor pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the mTORC1-mediated signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the p75 NTR receptor-mediated signalling pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the p75NTR recruits signalling complexes pathway from the Reactome Pathways 2024 dataset.