Erythropoietin activates RAS

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Results for "Erythropoietin activates RAS": 2 genes, 166 gene sets

Name
EPOR Gene erythropoietin receptor This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
EPO Gene erythropoietin This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
Erythropoietin activates RAS Gene Set From Reactome Pathways 2024 proteins participating in the Erythropoietin activates RAS pathway from the Reactome Pathways 2024 dataset.
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Gene Set From Reactome Pathways 2024 proteins participating in the Erythropoietin activates Phosphoinositide-3-kinase (PI3K) pathway from the Reactome Pathways 2024 dataset.
Erythropoietin activates Phospholipase C gamma (PLCG) Gene Set From Reactome Pathways 2024 proteins participating in the Erythropoietin activates Phospholipase C gamma (PLCG) pathway from the Reactome Pathways 2024 dataset.
Erythropoietin activates STAT5 Gene Set From Reactome Pathways 2024 proteins participating in the Erythropoietin activates STAT5 pathway from the Reactome Pathways 2024 dataset.
MET activates RAS signaling Gene Set From Reactome Pathways 2024 proteins participating in the MET activates RAS signaling pathway from the Reactome Pathways 2024 dataset.
erythropoietin mediated neuroprotection through nf-kb Gene Set From Biocarta Pathways proteins participating in the erythropoietin mediated neuroprotection through nf-kb pathway from the Biocarta Pathways dataset.
Erythropoietin Gene Set From CTD Gene-Chemical Interactions genes/proteins interacting with the chemical Erythropoietin from the curated CTD Gene-Chemical Interactions dataset.
erythropoietin induced hypertension Gene Set From GAD Gene-Disease Associations genes associated with the disease erythropoietin induced hypertension in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
erythropoietin Gene Set From GAD Gene-Disease Associations genes associated with the disease erythropoietin in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
erythropoietin Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term erythropoietin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
response to erythropoietin Gene Set From GO Biological Process Annotations 2015 genes participating in the response to erythropoietin biological process from the curated GO Biological Process Annotations 2015 dataset.
erythropoietin-mediated signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the erythropoietin-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
cellular response to erythropoietin Gene Set From GO Biological Process Annotations 2015 genes participating in the cellular response to erythropoietin biological process from the curated GO Biological Process Annotations 2015 dataset.
erythropoietin receptor binding Gene Set From GO Molecular Function Annotations 2015 genes performing the erythropoietin receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
erythropoietin receptor activity Gene Set From GO Molecular Function Annotations 2015 genes performing the erythropoietin receptor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.
Erythropoietin receptor Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Erythropoietin receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Erythropoietin/thrombopoeitin Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Erythropoietin/thrombopoeitin protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Erythropoietin/thrombopoeitin, conserved site Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Erythropoietin/thrombopoeitin, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Growth hormone/erythropoietin receptor, ligand binding Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Growth hormone/erythropoietin receptor, ligand binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Erythropoietin Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Erythropoietin protein domain from the InterPro Predicted Protein Domain Annotations dataset.
increased circulating erythropoietin level Gene Set From MPO Gene-Phenotype Associations gene mutations causing the increased circulating erythropoietin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
abnormal circulating erythropoietin level Gene Set From MPO Gene-Phenotype Associations gene mutations causing the abnormal circulating erythropoietin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
increased erythropoietin level Gene Set From MPO Gene-Phenotype Associations gene mutations causing the increased erythropoietin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
abnormal erythropoietin level Gene Set From MPO Gene-Phenotype Associations gene mutations causing the abnormal erythropoietin level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
Erythropoietin-Resistant Anemia Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Erythropoietin-Resistant Anemia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Polycythemia Due To Erythropoietin Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Polycythemia Due To Erythropoietin in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
erythropoietin-mediated signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the erythropoietin-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
cellular response to erythropoietin Gene Set From GO Biological Process Annotations 2023 genes participating in the cellular response to erythropoietin biological process from the curated GO Biological Process Annotations 2023 dataset.
response to erythropoietin Gene Set From GO Biological Process Annotations 2023 genes participating in the response to erythropoietin biological process from the curated GO Biological Process Annotations 2023 dataset.
erythropoietin receptor binding Gene Set From GO Molecular Function Annotations 2023 genes performing the erythropoietin receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
erythropoietin receptor activity Gene Set From GO Molecular Function Annotations 2023 genes performing the erythropoietin receptor activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.
increased circulating erythropoietin level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the increased circulating erythropoietin level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
decreased circulating erythropoietin level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased circulating erythropoietin level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
Signaling by Erythropoietin Gene Set From Reactome Pathways 2024 proteins participating in the Signaling by Erythropoietin pathway from the Reactome Pathways 2024 dataset.
erythropoietin-mediated signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the erythropoietin-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
cellular response to erythropoietin Gene Set From GO Biological Process Annotations 2025 genes participating in the cellular response to erythropoietin biological process from the curated GO Biological Process Annotations 2025 dataset.
response to erythropoietin Gene Set From GO Biological Process Annotations 2025 genes participating in the response to erythropoietin biological process from the curated GO Biological Process Annotations 2025 dataset.
erythropoietin receptor binding Gene Set From GO Molecular Function Annotations 2025 genes performing the erythropoietin receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.
erythropoietin receptor activity Gene Set From GO Molecular Function Annotations 2025 genes performing the erythropoietin receptor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
Serum erythropoietin levels Gene Set From GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the Serum erythropoietin levels phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
Erythropoietin levels Gene Set From GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the Erythropoietin levels phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
activates Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term activates in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
ATF4 activates genes Gene Set From Reactome Pathways 2014 proteins participating in the ATF4 activates genes pathway from the Reactome Pathways dataset.
ChREBP activates metabolic gene expression Gene Set From Reactome Pathways 2014 proteins participating in the ChREBP activates metabolic gene expression pathway from the Reactome Pathways dataset.
PIP3 activates AKT signaling Gene Set From Reactome Pathways 2014 proteins participating in the PIP3 activates AKT signaling pathway from the Reactome Pathways dataset.
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Gene Set From Reactome Pathways 2014 proteins participating in the Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway from the Reactome Pathways dataset.
TGF-beta receptor signaling activates SMADs Gene Set From Reactome Pathways 2014 proteins participating in the TGF-beta receptor signaling activates SMADs pathway from the Reactome Pathways dataset.
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Gene Set From Reactome Pathways 2014 proteins participating in the LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production pathway from the Reactome Pathways dataset.
XBP1(S) activates chaperone genes Gene Set From Reactome Pathways 2014 proteins participating in the XBP1(S) activates chaperone genes pathway from the Reactome Pathways dataset.
PPARA activates gene expression Gene Set From Reactome Pathways 2014 proteins participating in the PPARA activates gene expression pathway from the Reactome Pathways dataset.
ATF6-alpha activates chaperone genes Gene Set From Reactome Pathways 2014 proteins participating in the ATF6-alpha activates chaperone genes pathway from the Reactome Pathways dataset.
RORA activates circadian gene expression Gene Set From Reactome Pathways 2014 proteins participating in the RORA activates circadian gene expression pathway from the Reactome Pathways dataset.
TAK1 activates NFkB by phosphorylation and activation of IKKs complex Gene Set From Reactome Pathways 2014 proteins participating in the TAK1 activates NFkB by phosphorylation and activation of IKKs complex pathway from the Reactome Pathways dataset.
BMAL1:CLOCK,NPAS2 activates circadian gene expression Gene Set From Reactome Pathways 2014 proteins participating in the BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway from the Reactome Pathways dataset.
ATF6-alpha activates chaperones Gene Set From Reactome Pathways 2014 proteins participating in the ATF6-alpha activates chaperones pathway from the Reactome Pathways dataset.
IRE1alpha activates chaperones Gene Set From Reactome Pathways 2014 proteins participating in the IRE1alpha activates chaperones pathway from the Reactome Pathways dataset.
ATF4 activates genes in response to endoplasmic reticulum stress Gene Set From Reactome Pathways 2024 proteins participating in the ATF4 activates genes in response to endoplasmic reticulum stress pathway from the Reactome Pathways 2024 dataset.
ATF6 (ATF6-alpha) activates chaperone genes Gene Set From Reactome Pathways 2024 proteins participating in the ATF6 (ATF6-alpha) activates chaperone genes pathway from the Reactome Pathways 2024 dataset.
ATF6 (ATF6-alpha) activates chaperones Gene Set From Reactome Pathways 2024 proteins participating in the ATF6 (ATF6-alpha) activates chaperones pathway from the Reactome Pathways 2024 dataset.
ATF6B (ATF6-beta) activates chaperones Gene Set From Reactome Pathways 2024 proteins participating in the ATF6B (ATF6-beta) activates chaperones pathway from the Reactome Pathways 2024 dataset.
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Gene Set From Reactome Pathways 2024 proteins participating in the Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway from the Reactome Pathways 2024 dataset.
BDNF activates NTRK2 (TRKB) signaling Gene Set From Reactome Pathways 2024 proteins participating in the BDNF activates NTRK2 (TRKB) signaling pathway from the Reactome Pathways 2024 dataset.
BMAL1:CLOCK,NPAS2 activates circadian gene expression Gene Set From Reactome Pathways 2024 proteins participating in the BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway from the Reactome Pathways 2024 dataset.
Calcineurin activates NFAT Gene Set From Reactome Pathways 2024 proteins participating in the Calcineurin activates NFAT pathway from the Reactome Pathways 2024 dataset.
ChREBP activates metabolic gene expression Gene Set From Reactome Pathways 2024 proteins participating in the ChREBP activates metabolic gene expression pathway from the Reactome Pathways 2024 dataset.
ERBB2 Activates PTK6 Signaling Gene Set From Reactome Pathways 2024 proteins participating in the ERBB2 Activates PTK6 Signaling pathway from the Reactome Pathways 2024 dataset.
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells Gene Set From Reactome Pathways 2024 proteins participating in the High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells pathway from the Reactome Pathways 2024 dataset.
IFNG signaling activates MAPKs Gene Set From Reactome Pathways 2024 proteins participating in the IFNG signaling activates MAPKs pathway from the Reactome Pathways 2024 dataset.
IRE1alpha activates chaperones Gene Set From Reactome Pathways 2024 proteins participating in the IRE1alpha activates chaperones pathway from the Reactome Pathways 2024 dataset.
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Gene Set From Reactome Pathways 2024 proteins participating in the LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production pathway from the Reactome Pathways 2024 dataset.
MET activates PI3K/AKT signaling Gene Set From Reactome Pathways 2024 proteins participating in the MET activates PI3K/AKT signaling pathway from the Reactome Pathways 2024 dataset.
MET activates PTK2 signaling Gene Set From Reactome Pathways 2024 proteins participating in the MET activates PTK2 signaling pathway from the Reactome Pathways 2024 dataset.
MET activates PTPN11 Gene Set From Reactome Pathways 2024 proteins participating in the MET activates PTPN11 pathway from the Reactome Pathways 2024 dataset.
MET activates RAP1 and RAC1 Gene Set From Reactome Pathways 2024 proteins participating in the MET activates RAP1 and RAC1 pathway from the Reactome Pathways 2024 dataset.
MET activates STAT3 Gene Set From Reactome Pathways 2024 proteins participating in the MET activates STAT3 pathway from the Reactome Pathways 2024 dataset.
MTF1 activates gene expression Gene Set From Reactome Pathways 2024 proteins participating in the MTF1 activates gene expression pathway from the Reactome Pathways 2024 dataset.
NTF3 activates NTRK2 (TRKB) signaling Gene Set From Reactome Pathways 2024 proteins participating in the NTF3 activates NTRK2 (TRKB) signaling pathway from the Reactome Pathways 2024 dataset.
NTF3 activates NTRK3 signaling Gene Set From Reactome Pathways 2024 proteins participating in the NTF3 activates NTRK3 signaling pathway from the Reactome Pathways 2024 dataset.
NTF4 activates NTRK2 (TRKB) signaling Gene Set From Reactome Pathways 2024 proteins participating in the NTF4 activates NTRK2 (TRKB) signaling pathway from the Reactome Pathways 2024 dataset.
NTRK2 activates RAC1 Gene Set From Reactome Pathways 2024 proteins participating in the NTRK2 activates RAC1 pathway from the Reactome Pathways 2024 dataset.
PIP3 activates AKT signaling Gene Set From Reactome Pathways 2024 proteins participating in the PIP3 activates AKT signaling pathway from the Reactome Pathways 2024 dataset.
PPARA activates gene expression Gene Set From Reactome Pathways 2024 proteins participating in the PPARA activates gene expression pathway from the Reactome Pathways 2024 dataset.
PTK6 Activates STAT3 Gene Set From Reactome Pathways 2024 proteins participating in the PTK6 Activates STAT3 pathway from the Reactome Pathways 2024 dataset.
RORA activates gene expression Gene Set From Reactome Pathways 2024 proteins participating in the RORA activates gene expression pathway from the Reactome Pathways 2024 dataset.
SARS-CoV-1 activates/modulates innate immune responses Gene Set From Reactome Pathways 2024 proteins participating in the SARS-CoV-1 activates/modulates innate immune responses pathway from the Reactome Pathways 2024 dataset.
SARS-CoV-2 activates/modulates innate and adaptive immune responses Gene Set From Reactome Pathways 2024 proteins participating in the SARS-CoV-2 activates/modulates innate and adaptive immune responses pathway from the Reactome Pathways 2024 dataset.
TGF-beta receptor signaling activates SMADs Gene Set From Reactome Pathways 2024 proteins participating in the TGF-beta receptor signaling activates SMADs pathway from the Reactome Pathways 2024 dataset.
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells Gene Set From Reactome Pathways 2024 proteins participating in the Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells pathway from the Reactome Pathways 2024 dataset.
XBP1(S) activates chaperone genes Gene Set From Reactome Pathways 2024 proteins participating in the XBP1(S) activates chaperone genes pathway from the Reactome Pathways 2024 dataset.
ras-independent pathway in nk cell-mediated cytotoxicity Gene Set From Biocarta Pathways proteins participating in the ras-independent pathway in nk cell-mediated cytotoxicity pathway from the Biocarta Pathways dataset.
ras signaling pathway Gene Set From Biocarta Pathways proteins participating in the ras signaling pathway pathway from the Biocarta Pathways dataset.
influence of ras and rho proteins on g1 to s transition Gene Set From Biocarta Pathways proteins participating in the influence of ras and rho proteins on g1 to s transition pathway from the Biocarta Pathways dataset.
p21(ras)GAP-Fyn-Lyn-Yes complex, thrombin stimulated Gene Set From CORUM Protein Complexes proteins in the p21(ras)GAP-Fyn-Lyn-Yes complex, thrombin stimulated protein complex from the CORUM Protein Complexes dataset.
RAF1-RAS complex, EGF induced Gene Set From CORUM Protein Complexes proteins in the RAF1-RAS complex, EGF induced protein complex from the CORUM Protein Complexes dataset.
BRAF-CNK1 complex, not RAS stimulated Gene Set From CORUM Protein Complexes proteins in the BRAF-CNK1 complex, not RAS stimulated protein complex from the CORUM Protein Complexes dataset.
RAF1-BRAF complex, RAS stimulated Gene Set From CORUM Protein Complexes proteins in the RAF1-BRAF complex, RAS stimulated protein complex from the CORUM Protein Complexes dataset.
RAF1-CNK1 complex, RAS stimulated Gene Set From CORUM Protein Complexes proteins in the RAF1-CNK1 complex, RAS stimulated protein complex from the CORUM Protein Complexes dataset.
h-ras allele loss Gene Set From GAD Gene-Disease Associations genes associated with the disease h-ras allele loss in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
activated k-ras gene Gene Set From GAD Gene-Disease Associations genes associated with the disease activated k-ras gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
activation of the c-k-ras-2 protooncogene Gene Set From GAD Gene-Disease Associations genes associated with the disease activation of the c-k-ras-2 protooncogene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
ras Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term ras in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
negative regulation of ras protein signal transduction Gene Set From GO Biological Process Annotations 2015 genes participating in the negative regulation of ras protein signal transduction biological process from the curated GO Biological Process Annotations 2015 dataset.
ras protein signal transduction Gene Set From GO Biological Process Annotations 2015 genes participating in the ras protein signal transduction biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of ras protein signal transduction Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of ras protein signal transduction biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of ras protein signal transduction Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of ras protein signal transduction biological process from the curated GO Biological Process Annotations 2015 dataset.
ras gtpase binding Gene Set From GO Molecular Function Annotations 2015 genes performing the ras gtpase binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
ras palmitoyltransferase activity Gene Set From GO Molecular Function Annotations 2015 genes performing the ras palmitoyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.
ras guanyl-nucleotide exchange factor activity Gene Set From GO Molecular Function Annotations 2015 genes performing the ras guanyl-nucleotide exchange factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.
Small GTPase superfamily, Ras type Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Small GTPase superfamily, Ras type protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras GTPase-activating protein, conserved site Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras GTPase-activating protein, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras GTPase-activating protein Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras GTPase-activating protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras-related protein Ral Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras-related protein Ral protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras guanine nucleotide exchange factor domain Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras guanine nucleotide exchange factor domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras guanine-nucleotide exchange factor, conserved site Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras guanine-nucleotide exchange factor, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras guanyl-releasing protein 3 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras guanyl-releasing protein 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Kinase suppressor of RAS, SAM-like domain Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Kinase suppressor of RAS, SAM-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras-association Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras-association protein domain from the InterPro Predicted Protein Domain Annotations dataset.
RAS guanyl-releasing protein 1 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the RAS guanyl-releasing protein 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Connector enhancer of kinase suppressor of ras 2 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Connector enhancer of kinase suppressor of ras 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras guanine-nucleotide exchange factors catalytic domain Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras guanine-nucleotide exchange factors catalytic domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Raf-like Ras-binding Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Raf-like Ras-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras-like guanine nucleotide exchange factor, N-terminal Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ras-like guanine nucleotide exchange factor, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ras Pathway Gene Set From PANTHER Pathways proteins participating in the Ras Pathway pathway from the PANTHER Pathways dataset.
ras Gene Set From Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term ras in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.
ras-proteins Gene Set From Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term ras-proteins in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.
Ras signaling in the CD4+ TCR pathway Gene Set From PID Pathways proteins participating in the Ras signaling in the CD4+ TCR pathway pathway from the PID Pathways dataset.
Regulation of Ras family activation Gene Set From PID Pathways proteins participating in the Regulation of Ras family activation pathway from the PID Pathways dataset.
Signalling to RAS Gene Set From Reactome Pathways 2014 proteins participating in the Signalling to RAS pathway from the Reactome Pathways dataset.
Ras activation uopn Ca2+ infux through NMDA receptor Gene Set From Reactome Pathways 2014 proteins participating in the Ras activation uopn Ca2+ infux through NMDA receptor pathway from the Reactome Pathways dataset.
Activation of RAS in B cells Gene Set From Reactome Pathways 2014 proteins participating in the Activation of RAS in B cells pathway from the Reactome Pathways dataset.
CREB phosphorylation through the activation of Ras Gene Set From Reactome Pathways 2014 proteins participating in the CREB phosphorylation through the activation of Ras pathway from the Reactome Pathways dataset.
Ras-Associated Autoimmune Leukoproliferative Disorder Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Ras-Associated Autoimmune Leukoproliferative Disorder in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Ras protein signal transduction Gene Set From GO Biological Process Annotations 2023 genes participating in the Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of Ras protein signal transduction Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2023 dataset.
negative regulation of Ras protein signal transduction Gene Set From GO Biological Process Annotations 2023 genes participating in the negative regulation of Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of Ras protein signal transduction Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2023 dataset.
Ras palmitoyltransferase activity Gene Set From GO Molecular Function Annotations 2023 genes performing the Ras palmitoyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.
Ras signaling Gene Set From WikiPathways Pathways 2024 proteins participating in the Ras signaling pathway from the WikiPathways Pathways 2024 dataset.
RAS and bradykinin pathways in COVID 19 Gene Set From WikiPathways Pathways 2024 proteins participating in the RAS and bradykinin pathways in COVID 19 pathway from the WikiPathways Pathways 2024 dataset.
Activated NTRK2 signals through RAS Gene Set From Reactome Pathways 2024 proteins participating in the Activated NTRK2 signals through RAS pathway from the Reactome Pathways 2024 dataset.
Activated NTRK3 signals through RAS Gene Set From Reactome Pathways 2024 proteins participating in the Activated NTRK3 signals through RAS pathway from the Reactome Pathways 2024 dataset.
Activation of RAS in B cells Gene Set From Reactome Pathways 2024 proteins participating in the Activation of RAS in B cells pathway from the Reactome Pathways 2024 dataset.
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling Gene Set From Reactome Pathways 2024 proteins participating in the CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling pathway from the Reactome Pathways 2024 dataset.
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases Gene Set From Reactome Pathways 2024 proteins participating in the PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases pathway from the Reactome Pathways 2024 dataset.
RAS GTPase cycle mutants Gene Set From Reactome Pathways 2024 proteins participating in the RAS GTPase cycle mutants pathway from the Reactome Pathways 2024 dataset.
RAS processing Gene Set From Reactome Pathways 2024 proteins participating in the RAS processing pathway from the Reactome Pathways 2024 dataset.
RAS signaling downstream of NF1 loss-of-function variants Gene Set From Reactome Pathways 2024 proteins participating in the RAS signaling downstream of NF1 loss-of-function variants pathway from the Reactome Pathways 2024 dataset.
Ras activation upon Ca2+ influx through NMDA receptor Gene Set From Reactome Pathways 2024 proteins participating in the Ras activation upon Ca2+ influx through NMDA receptor pathway from the Reactome Pathways 2024 dataset.
Regulation of RAS by GAPs Gene Set From Reactome Pathways 2024 proteins participating in the Regulation of RAS by GAPs pathway from the Reactome Pathways 2024 dataset.
Signaling by RAS GAP mutants Gene Set From Reactome Pathways 2024 proteins participating in the Signaling by RAS GAP mutants pathway from the Reactome Pathways 2024 dataset.
Signaling by RAS GTPase mutants Gene Set From Reactome Pathways 2024 proteins participating in the Signaling by RAS GTPase mutants pathway from the Reactome Pathways 2024 dataset.
Signaling by RAS mutants Gene Set From Reactome Pathways 2024 proteins participating in the Signaling by RAS mutants pathway from the Reactome Pathways 2024 dataset.
Signaling downstream of RAS mutants Gene Set From Reactome Pathways 2024 proteins participating in the Signaling downstream of RAS mutants pathway from the Reactome Pathways 2024 dataset.
Signalling to RAS Gene Set From Reactome Pathways 2024 proteins participating in the Signalling to RAS pathway from the Reactome Pathways 2024 dataset.
Ras protein signal transduction Gene Set From GO Biological Process Annotations 2025 genes participating in the Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2025 dataset.
positive regulation of Ras protein signal transduction Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2025 dataset.
negative regulation of Ras protein signal transduction Gene Set From GO Biological Process Annotations 2025 genes participating in the negative regulation of Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of Ras protein signal transduction Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of Ras protein signal transduction biological process from the curated GO Biological Process Annotations 2025 dataset.
Ras palmitoyltransferase activity Gene Set From GO Molecular Function Annotations 2025 genes performing the Ras palmitoyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
NIH-3T3-ras cell Gene Set From TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 proteins co-occuring with the tissue NIH-3T3-ras cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 dataset.
Ras guanyl-nucleotide exchange factor complex Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Ras guanyl-nucleotide exchange factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
Ras family interactors Gene Set From CM4AI U2OS Cell Map Protein Localization Assemblies proteins comprising Ras family interactors assembly using integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.
Ras signaling pathway Gene Set From KEGG Pathways 2026 proteins participating in the Ras signaling pathway pathway from the KEGG Pathways 2026 dataset.
RAS INHIBITOR Gene Set From DGIdb Drug Targets 2026 interacting proteins for the RAS INHIBITOR drug from theDGIdb Drug Targets 2026 dataset.
RAS PEPTIDE CANCER VACCINE Gene Set From DGIdb Drug Targets 2026 interacting proteins for the RAS PEPTIDE CANCER VACCINE drug from theDGIdb Drug Targets 2026 dataset.

Harmonizome 3.0

EPOR Gene

EPO Gene

Erythropoietin activates RAS Gene Set

Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Gene Set

Erythropoietin activates Phospholipase C gamma (PLCG) Gene Set

Erythropoietin activates STAT5 Gene Set

MET activates RAS signaling Gene Set

erythropoietin mediated neuroprotection through nf-kb Gene Set

Erythropoietin Gene Set

erythropoietin induced hypertension Gene Set

erythropoietin Gene Set

erythropoietin Gene Set

response to erythropoietin Gene Set

erythropoietin-mediated signaling pathway Gene Set

cellular response to erythropoietin Gene Set

erythropoietin receptor binding Gene Set

erythropoietin receptor activity Gene Set

Erythropoietin receptor Gene Set

Erythropoietin/thrombopoeitin Gene Set

Erythropoietin/thrombopoeitin, conserved site Gene Set

Growth hormone/erythropoietin receptor, ligand binding Gene Set

Erythropoietin Gene Set

increased circulating erythropoietin level Gene Set

abnormal circulating erythropoietin level Gene Set

increased erythropoietin level Gene Set

abnormal erythropoietin level Gene Set

Erythropoietin-Resistant Anemia Gene Set

Polycythemia Due To Erythropoietin Gene Set

erythropoietin-mediated signaling pathway Gene Set

cellular response to erythropoietin Gene Set

response to erythropoietin Gene Set

erythropoietin receptor binding Gene Set

erythropoietin receptor activity Gene Set

increased circulating erythropoietin level Gene Set

decreased circulating erythropoietin level Gene Set

Signaling by Erythropoietin Gene Set

erythropoietin-mediated signaling pathway Gene Set

cellular response to erythropoietin Gene Set

response to erythropoietin Gene Set

erythropoietin receptor binding Gene Set

erythropoietin receptor activity Gene Set

Serum erythropoietin levels Gene Set

Erythropoietin levels Gene Set

activates Gene Set

ATF4 activates genes Gene Set

ChREBP activates metabolic gene expression Gene Set

PIP3 activates AKT signaling Gene Set

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Gene Set

TGF-beta receptor signaling activates SMADs Gene Set

LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Gene Set

XBP1(S) activates chaperone genes Gene Set

PPARA activates gene expression Gene Set

ATF6-alpha activates chaperone genes Gene Set

RORA activates circadian gene expression Gene Set

TAK1 activates NFkB by phosphorylation and activation of IKKs complex Gene Set

BMAL1:CLOCK,NPAS2 activates circadian gene expression Gene Set

ATF6-alpha activates chaperones Gene Set

IRE1alpha activates chaperones Gene Set

ATF4 activates genes in response to endoplasmic reticulum stress Gene Set

ATF6 (ATF6-alpha) activates chaperone genes Gene Set

ATF6 (ATF6-alpha) activates chaperones Gene Set

ATF6B (ATF6-beta) activates chaperones Gene Set

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Gene Set

BDNF activates NTRK2 (TRKB) signaling Gene Set

BMAL1:CLOCK,NPAS2 activates circadian gene expression Gene Set

Calcineurin activates NFAT Gene Set

ChREBP activates metabolic gene expression Gene Set

ERBB2 Activates PTK6 Signaling Gene Set

High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells Gene Set

IFNG signaling activates MAPKs Gene Set

IRE1alpha activates chaperones Gene Set

LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Gene Set

MET activates PI3K/AKT signaling Gene Set

MET activates PTK2 signaling Gene Set

MET activates PTPN11 Gene Set

MET activates RAP1 and RAC1 Gene Set

MET activates STAT3 Gene Set

MTF1 activates gene expression Gene Set

NTF3 activates NTRK2 (TRKB) signaling Gene Set