Harmonizome 3.0

testis expressed 28 pseudogene 2

testis expressed 28 pseudogene 1

testis-specific transcript, Y-linked 25, pseudogene

cancer/testis antigen family 45, member A9

cancer/testis antigen family 45, member A8

cancer/testis antigen family 45, member A1

cancer/testis antigen family 45, member A2

This gene represents one of a cluster of several similar genes located on the q arm of chromosome X. The genes in this cluster encode members of the cancer/testis (CT) family of antigens, and are distinct from other CT antigens. These antigens are thought to be novel therapeutic targets for human cancers. [provided by RefSeq, Apr 2014]

cancer/testis antigen family 45, member A5

This gene represents one of a cluster of several similar genes located on the q arm of chromosome X. The genes in this cluster encode members of the cancer/testis (CT) family of antigens, and are distinct from other CT antigens. These antigens are thought to be novel therapeutic targets for human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

cancer/testis antigen family 45, member A4

cancer/testis antigen family 45, member A7

cancer/testis antigen family 45, member A6

testis specific protein, Y-linked 8

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including gonadal mesoderm development; nucleosome assembly; and spermatogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 2

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including gonadal mesoderm development; nucleosome assembly; and spermatogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 1

The protein encoded by this gene is found only in testicular tissue and may be involved in spermatogenesis. Many functional paralogs and pseudogenes of this gene are present in a cluster in humans, but only a single, nonfunctional orthologous gene is found in mouse. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

testis expressed 26

Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 22

Predicted to be located in acrosomal vesicle. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 28

Predicted to be located in membrane. Predicted to be active in endomembrane system. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 29

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

cancer/testis antigen 55 pseudogene

testis-expressed, seven-twelve, leukemia

cancer/testis antigen family 45, member A3

testis specific protein, Y-linked 18, pseudogene

testis specific protein, Y-linked 23, pseudogene

testis-specific transcript, Y-linked 13B

testis specific protein, Y-linked 4

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including gonadal mesoderm development; nucleosome assembly; and spermatogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 3

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in sex differentiation. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis-specific transcript, Y-linked 28, pseudogene

testis specific protein, Y-linked 17, pseudogene

testis expressed 15

This gene encodes a protein that is required for DNA double-strand break repair, chromosome synapsis, and meiotic recombination in spermatocytes. Male mice with a knockout of the orthologous gene are viable but sterile. Loss-of-function mutations in the orthologous mouse gene cause early meiotic arrest in spermatocytes, before the mid-pachytene stage. Naturally occurring mutations in this gene are associated with nonobstructive azoospermia. [provided by RefSeq, Apr 2017]

testis expressed 14

The protein encoded by this gene is necessary for intercellular bridges in germ cells, which are required for spermatogenesis. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]

testis expressed 11

This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

testis expressed 10

Located in mitochondrion and nucleoplasm. Part of MLL1 complex. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 12

This gene is similar to a mouse gene that is expressed in the testis. [provided by RefSeq, Jul 2008]

cancer/testis antigen family 45, member A11, pseudogene

prostate and testis expressed 4

Enables acetylcholine receptor regulator activity. Involved in regulation of neurotransmitter receptor activity. Located in acrosomal vesicle and extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 19

Predicted to enable piRNA binding activity. Involved in transposable element silencing. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

cancer/testis antigen family 45, member B1 pseudogene

testis highly expressed protein 5

cancer/testis antigen family 45, member A10

Enables identical protein binding activity. [provided by Alliance of Genome Resources, Mar 2025]

cytochrome c, testis, pseudogene

Predicted to enable heme binding activity. Predicted to act upstream of or within hydrogen peroxide metabolic process and positive regulation of intrinsic apoptotic signaling pathway. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 20, pseudogene

testis-specific transcript, Y-linked 3B (non-protein coding)

There are two copies of this gene within the P1 palindrome on chromosome Y. This record represents the more centromeric copy. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 17A (non-protein coding)

There are three copies of this gene on chromosome Y. This record represents the most centromeric copy. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 17B (non-protein coding)

There are three copies of this gene on chromosome Y. This record represents the middle copy, which is within the P1 palindrome. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 17C (non-protein coding)

There are three copies of this gene on chromosome Y. This record represents the most telomeric copy, which is within the P1 palindrome. [provided by RefSeq, Jul 2008]

cancer/testis antigen 1A

The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome. [provided by RefSeq, Dec 2015]

cancer/testis antigen 1B

The protein encoded by this gene is an antigen that is overexpressed in many cancers but that is also expressed in normal testis. This gene is found in a duplicated region of the X-chromosome and therefore has a neighboring gene of identical sequence. [provided by RefSeq, Jan 2012]

fetal and adult testis expressed 1

This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. [provided by RefSeq, Jan 2010]

testis specific protein, Y-linked 12, pseudogene

cancer/testis antigen 55

Involved in spermatogenesis. Located in acrosomal vesicle and sperm flagellum. Implicated in X-linked spermatogenic failure 7. [provided by Alliance of Genome Resources, Mar 2025]

bromodomain, testis-specific

BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

testis-specific transcript, Y-linked 23B (non-protein coding)

H1 histone family, member N, testis-specific

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family. The related mouse gene encodes a testis specific protein that is required for spermatogenesis and male fertility. [provided by RefSeq, Oct 2015]

testis expressed 43

Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be active in axonemal B tubule inner sheath and sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 40

Predicted to be involved in flagellated sperm motility; male meiotic nuclear division; and sperm capacitation. Located in cytoplasm and sperm principal piece. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 41 (non-protein coding)

testis-specific transcript, Y-linked 6B (non-protein coding)

There are two copies of this locus in the P3 palindrome on chromosome Y. This record represents the more centromeric copy. [provided by RefSeq, Jul 2008]

prion protein (testis specific)

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

testis and ovary specific PAZ domain containing 1

Predicted to be involved in spermatocyte division. Predicted to act upstream of or within apoptotic process; ectopic germ cell programmed cell death; and lncRNA transcription. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 33

Predicted to be located in sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 25, pseudogene

peroxisomal, testis specific 1

Predicted to be involved in positive regulation of apoptotic process and spermatogenesis. Predicted to be active in nucleus and peroxisome. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 11, pseudogene

prostate and testis expressed 1

Predicted to enable acetylcholine receptor regulator activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

prostate and testis expressed 3

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

prostate and testis expressed 2

Located in extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

testis-specific kinase 1

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

testis-specific kinase 2

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

testis-specific transcript, Y-linked 26, pseudogene

testis-specific serine kinase substrate

This gene may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of the encoded protein is highest in the testis and down-regulated in testicular cancer. The gene is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 2 (non-protein coding)

testis-specific transcript, Y-linked 3 (non-protein coding)

There are two copies of this gene within the P1 palindrome on chromosome Y. This record represents the more telomeric copy. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 1 (non-protein coding)

testis-specific transcript, Y-linked 6 (non-protein coding)

There are two copies of this locus in the P3 palindrome on chromosome Y. This record represents the more telomeric copy. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 7 (non-protein coding)

testis-specific transcript, Y-linked 4 (non-protein coding)

There are three copies of this gene on chromosome Y. This record represents the most centromeric copy. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 5 (non-protein coding)

There is a single copy of this gene on chromosome Y at the center of the P3 palindrome. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 8 (non-protein coding)

testis specific protein, Y-linked 19, pseudogene

testis expressed 38

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 30

testis expressed 37

Predicted to be involved in flagellated sperm motility. Located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 36

testis expressed 35

Located in microtubule cytoskeleton. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 9, pseudogene

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including gonadal mesoderm development; nucleosome assembly; and spermatogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

cancer/testis antigen 83

Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis development related protein

Acts upstream of or within spermatogenesis. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis-specific serine kinase 1A pseudogene

testis-specific serine kinase 1B

TSSK1 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008]

testis expressed sequence 13-like

Predicted to enable mRNA binding activity. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 10

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in sex differentiation. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

cancer/testis antigen 2

This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

testis specific protein, Y-linked 22, pseudogene

testis-specific transcript, Y-linked 14 (non-protein coding)

testis-specific transcript, Y-linked 15 (non-protein coding)

testis-specific transcript, Y-linked 16 (non-protein coding)

testis-specific transcript, Y-linked 10 (non-protein coding)

testis-specific transcript, Y-linked 11 (non-protein coding)

testis-specific transcript, Y-linked 12 (non-protein coding)

testis-specific transcript, Y-linked 13 (non-protein coding)

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

testis-specific transcript, Y-linked 18 (non-protein coding)

testis-specific transcript, Y-linked 19 (non-protein coding)

testis-specific transcript, Y-linked 1B (non-protein coding)

testis-specific transcript, Y-linked 13C

testis-specific transcript, Y-linked 29, pseudogene

testis expressed 28 pseudogene

bromodomain, testis-specific pseudogene 1

testis-specific transcript, Y-linked 9A (non-protein coding)

This gene is transcribed but does not appear to encode a protein. Two identical copies of this gene are present in a palindromic region (P4) on chromosome Y. This record represents the more telomeric copy. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 9B (non-protein coding)

This gene is transcribed but does not appear to encode a protein. Two identical copies of this gene are present in a palindromic region (P4) on chromosome Y. This record represents the more centromeric copy. [provided by RefSeq, Jul 2008]

testis specific protein, Y-linked 14, pseudogene

testis-specific transcript, Y-linked 21B (non-protein coding)

testis expressed 21, pseudogene

cancer/testis antigen family 47, member A11 pseudogene

t-complex 11, testis-specific

Involved in germ cell development. Located in acrosomal vesicle and sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

MYCBP-associated, testis expressed 1

Involved in axonemal central apparatus assembly and spermatogenesis. Predicted to be located in motile cilium and radial spoke stalk. Implicated in spermatogenic failure 51. [provided by Alliance of Genome Resources, Mar 2025]

testis-specific serine kinase 2

TSSK2 belongs to a family of serine/threonine kinases highly expressed in testis (Hao et al., 2004 [PubMed 15044604]).[supplied by OMIM, Mar 2008]

testis-specific transcript, Y-linked 4C (non-protein coding)

There are three copies of this gene on chromosome Y. This record represents the most telomeric copy, which is within the P1 palindrome. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 4B (non-protein coding)

There are three copies of this gene on chromosome Y. This record represents the middle copy, which is within the P1 palindrome. [provided by RefSeq, Jul 2008]

adenosine deaminase domain containing 1 (testis-specific)

Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in RNA processing and adenosine to inosine editing. Predicted to act upstream of or within spermatid development. Predicted to be located in male germ cell nucleus. Predicted to be active in cytoplasm and nucleolus. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 13, pseudogene

phosphorylase kinase, gamma 2 (testis)

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]

cancer/testis antigen 62

cancer/testis antigen family 47, member A7

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. [provided by RefSeq, Sep 2010]

cancer/testis antigen family 47, member A4

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. [provided by RefSeq, Sep 2010]

cancer/testis antigen family 47, member A3

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. [provided by RefSeq, Sep 2010]

cancer/testis antigen family 47, member A2

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. [provided by RefSeq, Sep 2010]

cancer/testis antigen family 47, member A1

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. This locus is the most telomeric of the cluster.[provided by RefSeq, Sep 2010]

cancer/testis antigen family 47, member A9

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. [provided by RefSeq, Sep 2010]

cancer/testis antigen family 47, member A8

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. [provided by RefSeq, Sep 2010]

testis-specific transcript, Y-linked 24, pseudogene

metallothionein-like 5, testis-specific (tesmin)

Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may play a central role in the regulation of cell growth and differentiation and are involved in spermatogenesis. This gene encodes a metallothionein-like protein which has been shown to be expressed differentially in mouse testis and ovary. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

testis-specific transcript, Y-linked 7B (non-protein coding)

testis specific, 13

testis specific, 10

Predicted to enable structural molecule activity. Predicted to be involved in spermatogenesis. Predicted to act upstream of or within cell projection assembly. Predicted to be located in neuron projection; sperm fibrous sheath; and sperm principal piece. Predicted to be active in motile cilium. Implicated in spermatogenic failure 26. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 13B

This gene is similar to a mouse gene that is expressed in the testis. [provided by RefSeq, Jul 2008]

testis expressed 13A

This gene is similar to a mouse gene that is expressed in the testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

testis specific protein, Y-linked 7, pseudogene

testis specific protein, Y-linked 24, pseudogene

testis-specific transcript, Y-linked 8B (non-protein coding)

cancer/testis antigen family 47, member B1

testis-specific transcript, Y-linked 27, pseudogene

testis specific protein, Y-linked 16, pseudogene

testis-specific serine kinase 6

This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012]

testis-specific serine kinase 4

This gene encodes a member of the testis-specific serine/threonine kinase family. The encoded protein is thought to be involved in spermatogenesis via stimulation of the CREB/CRE responsive pathway through phosphorylation of the cAMP responsive element binding protein transcription factor. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

testis-specific serine kinase 3

This gene encodes a kinase expressed exclusively in the testis that is thought to play a role in either germ cell differentiation or mature sperm function. [provided by RefSeq, Jul 2008]

testis expressed 16, pseudogene

protein disulfide isomerase-like, testis expressed

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has has an N-terminal ER-signal sequence, two thioredoxin (TRX) domains with non-classical Ser-Lys-Gln-Ser and Ser-Lys-Lys-Cys motifs, respectively, two TRX-like domains, and a C-terminal ER-retention sequence. The protein lacks oxidoreductase activity in vitro and probably functions as a chaperone. This gene's expression appears to be limited to the testis. [provided by RefSeq, Dec 2016]

fatty acid binding protein 9, testis

Predicted to enable long-chain fatty acid binding activity. Predicted to be involved in long-chain fatty acid transport. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

t-complex 11, testis-specific-like 1

Predicted to be involved in signal transduction. Located in microtubule. [provided by Alliance of Genome Resources, Mar 2025]

t-complex 11, testis-specific-like 2

Predicted to be involved in muscle cell migration and signal transduction. Predicted to be located in cytoskeleton. Predicted to be part of cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

cancer/testis antigen 55 pseudogene

cancer/testis antigen family 47, member A6

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. [provided by RefSeq, Sep 2010]

cancer/testis antigen family 47, member A5

testis expressed 264 pseudogene

H2B histone family, member W, testis-specific

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the H2B histone family that is specifically expressed in sperm nuclei. A polymorphism in the 5' UTR of this gene is associated with male infertility.[provided by RefSeq, Oct 2015]

cytochrome c oxidase subunit VIb polypeptide 2 (testis)

Predicted to be involved in oxidative phosphorylation. Located in mitochondrial crista. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 101

Predicted to be involved in binding activity of sperm to zona pellucida; flagellated sperm motility; and regulation of flagellated sperm motility. Predicted to be located in acrosomal vesicle; extracellular region; and plasma membrane. Predicted to be active in plasma membrane raft. [provided by Alliance of Genome Resources, Mar 2025]

testis specific, 10 interacting protein

Predicted to be involved in cilium organization. Predicted to be located in ciliary basal body. Predicted to be active in photoreceptor connecting cilium. [provided by Alliance of Genome Resources, Mar 2025]

testis-specific transcript, Y-linked 31, pseudogene

testis specific protein, Y-linked 21, pseudogene

testis-specific transcript, Y-linked 2B (non-protein coding)

testis-specific transcript, Y-linked 21 (non-protein coding)

testis-specific transcript, Y-linked 20 (non-protein coding)

testis-specific transcript, Y-linked 23 (non-protein coding)

testis-specific transcript, Y-linked 22 (non-protein coding)

testis specific protein, Y-linked 26, pseudogene

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed sequence 13-like pseudogene

Predicted to enable mRNA binding activity. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 15, pseudogene

cancer/testis antigen 75

testis expressed 9

Located in centriolar satellite. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 2

Predicted to enable lipid binding activity. Predicted to be involved in signal transduction and sphingolipid metabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. [provided by Alliance of Genome Resources, Mar 2025]

t-complex-associated-testis-expressed 3

Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in cytosol and sperm flagellum. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

t-complex-associated-testis-expressed 1

Predicted to be involved in flagellated sperm motility. Predicted to be located in sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

testis, prostate and placenta expressed

Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 261

Predicted to enable COPII receptor activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to act upstream of or within positive regulation of apoptotic process. Predicted to be located in cytoplasm and membrane. Predicted to be active in COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 264

Enables signaling receptor activity. Involved in protein-DNA covalent cross-linking repair. Acts upstream of or within reticulophagy. Located in several cellular components, including autophagosome membrane; endoplasmic reticulum membrane; and replication fork. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein, Y-linked 6, pseudogene

poly(A) polymerase beta (testis specific)

Predicted to enable poly(A) RNA polymerase activity. Predicted to be involved in RNA 3'-end processing and mRNA processing. Predicted to be located in endoplasmic reticulum. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis development related 1 (non-protein coding)

Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

testis-specific serine kinase 5, pseudogene

testis specific protein, Y-linked 5, pseudogene

testis-specific transcript, Y-linked 30, pseudogene

cancer/testis antigen 83 pseudogene

adenosine deaminase domain containing 1 (testis-specific) pseudogene 2

adenosine deaminase domain containing 1 (testis-specific) pseudogene 1

cancer/testis antigen family 47, member A12

cancer/testis antigen family 47, member A11

This locus represents a member of the cancer/testis gene family 47. This family, also known as CT47, is comprised of 13 nearly identical loci clustered at Xq24. [provided by RefSeq, Sep 2010]

cancer/testis antigen family 47, member A10

testis expressed metallothionein like protein

Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may play a central role in the regulation of cell growth and differentiation and are involved in spermatogenesis. This gene encodes a metallothionein-like protein which has been shown to be expressed differentially in mouse testis and ovary. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

testis expressed basic protein 1

Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis specific protein Y-linked 9

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in several processes, including gonadal mesoderm development; nucleosome assembly; and spermatogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 44

Located in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 55

Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 47

testis expressed 46

Predicted to be involved in single fertilization. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

embryonic testis differentiation homolog B

testis expressed 49

Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and sperm flagellum. Predicted to be active in axonemal A tubule inner sheath. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 45

testis expressed 56, pseudogene

testis-specific serine/proline-rich protein

testis expressed 54

testis expressed 50

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed 53

testis expressed 51

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

embryonic testis differentiation homolog C

cancer/testis antigen family 47 member C1