| Name |
|---|
EGFR-AS1 GeneEGFR antisense RNA 1 |
EGFR Geneepidermal growth factor receptor The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020] |
ELDR GeneEGFR long non-coding downstream RNA Predicted to act upstream of or within regulation of gene expression and response to wounding. [provided by Alliance of Genome Resources, Mar 2025] |
EGFR downregulation Gene Setproteins participating in the EGFR downregulation pathway from the Reactome Pathways dataset. |
EGFR downregulation Gene Setproteins participating in the EGFR downregulation pathway from the Reactome Pathways 2024 dataset. |
cbl mediated ligand-induced downregulation of egf receptors pathway Gene SetFrom Biocarta Pathways proteins participating in the cbl mediated ligand-induced downregulation of egf receptors pathway pathway from the Biocarta Pathways dataset. |
downregulation Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term downregulation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Downregulation of TGF-beta receptor signaling Gene Setproteins participating in the Downregulation of TGF-beta receptor signaling pathway from the Reactome Pathways dataset. |
Nef mediated downregulation of CD28 cell surface expression Gene Setproteins participating in the Nef mediated downregulation of CD28 cell surface expression pathway from the Reactome Pathways dataset. |
Downregulation of ERBB4 signaling Gene Setproteins participating in the Downregulation of ERBB4 signaling pathway from the Reactome Pathways dataset. |
Nef mediated downregulation of MHC class I complex cell surface expression Gene Setproteins participating in the Nef mediated downregulation of MHC class I complex cell surface expression pathway from the Reactome Pathways dataset. |
Downregulation of ERBB2:ERBB3 signaling Gene Setproteins participating in the Downregulation of ERBB2:ERBB3 signaling pathway from the Reactome Pathways dataset. |
Downregulation of SMAD2/3:SMAD4 transcriptional activity Gene Setproteins participating in the Downregulation of SMAD2/3:SMAD4 transcriptional activity pathway from the Reactome Pathways dataset. |
Downregulation of ACE2 by SARS CoV 2 spike protein Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Downregulation of ACE2 by SARS CoV 2 spike protein pathway from the WikiPathways Pathways 2024 dataset. |
Downregulation of ERBB2 signaling Gene Setproteins participating in the Downregulation of ERBB2 signaling pathway from the Reactome Pathways 2024 dataset. |
Downregulation of ERBB2:ERBB3 signaling Gene Setproteins participating in the Downregulation of ERBB2:ERBB3 signaling pathway from the Reactome Pathways 2024 dataset. |
Downregulation of ERBB4 signaling Gene Setproteins participating in the Downregulation of ERBB4 signaling pathway from the Reactome Pathways 2024 dataset. |
Downregulation of SMAD2/3:SMAD4 transcriptional activity Gene Setproteins participating in the Downregulation of SMAD2/3:SMAD4 transcriptional activity pathway from the Reactome Pathways 2024 dataset. |
Downregulation of TGF-beta receptor signaling Gene Setproteins participating in the Downregulation of TGF-beta receptor signaling pathway from the Reactome Pathways 2024 dataset. |
Nef mediated downregulation of CD28 cell surface expression Gene Setproteins participating in the Nef mediated downregulation of CD28 cell surface expression pathway from the Reactome Pathways 2024 dataset. |
Nef mediated downregulation of MHC class I complex cell surface expression Gene Setproteins participating in the Nef mediated downregulation of MHC class I complex cell surface expression pathway from the Reactome Pathways 2024 dataset. |
grb2-egfr complex Gene SetFrom COMPARTMENTS Curated Protein Localization Evidence Scores proteins localized to the grb2-egfr complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. |
shc-egfr complex Gene SetFrom COMPARTMENTS Curated Protein Localization Evidence Scores proteins localized to the shc-egfr complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset. |
grb2-egfr complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the grb2-egfr complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. |
alphav-beta3 integrin-egfr complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the alphav-beta3 integrin-egfr complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. |
erbb4-egfr complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the erbb4-egfr complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. |
egfr-shc-grb2-sos complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the egfr-shc-grb2-sos complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. |
egfr-grb2-sos complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores proteins co-occuring with the egfr-grb2-sos complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset. |
CIN85-CBL-SH3GL2-EGFR complex, EGF stimulated Gene Setproteins in the CIN85-CBL-SH3GL2-EGFR complex, EGF stimulated protein complex from the CORUM Protein Complexes dataset. |
EGFR-containing signaling complex Gene Setproteins in the EGFR-containing signaling complex protein complex from the CORUM Protein Complexes dataset. |
SNX complex (SNX1a, SNX2, SNX4, EGFR) Gene Setproteins in the SNX complex (SNX1a, SNX2, SNX4, EGFR) protein complex from the CORUM Protein Complexes dataset. |
ITGAV-ITGB3-EGFR complex Gene Setproteins in the ITGAV-ITGB3-EGFR complex protein complex from the CORUM Protein Complexes dataset. |
Egfr-Grb2-mSos1 complex, EGF stimulated Gene Setproteins in the Egfr-Grb2-mSos1 complex, EGF stimulated protein complex from the CORUM Protein Complexes dataset. |
SH3KBP1-CBLB-EGFR complex Gene Setproteins in the SH3KBP1-CBLB-EGFR complex protein complex from the CORUM Protein Complexes dataset. |
EGFR-CBL-GRB2 complex Gene Setproteins in the EGFR-CBL-GRB2 complex protein complex from the CORUM Protein Complexes dataset. |
RIN1-STAM2-EGFR complex, EGF stimulated Gene Setproteins in the RIN1-STAM2-EGFR complex, EGF stimulated protein complex from the CORUM Protein Complexes dataset. |
EGFR tyrosine kinase inhibitor 324674 Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical EGFR tyrosine kinase inhibitor 324674 from the curated CTD Gene-Chemical Interactions dataset. |
HuMax-EGFr Gene Setinteracting proteins for the HuMax-EGFr drug from the curated DrugBank Drug Targets dataset. |
egfr Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term egfr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
grb2-egfr complex Gene SetFrom GO Cellular Component Annotations 2015 proteins localized to the grb2-egfr complex cellular component from the curated GO Cellular Component Annotations 2015 dataset. |
shc-egfr complex Gene SetFrom GO Cellular Component Annotations 2015 proteins localized to the shc-egfr complex cellular component from the curated GO Cellular Component Annotations 2015 dataset. |
EGFR Gene SetFrom Hub Proteins Protein-Protein Interactions interacting proteins for hub protein EGFR from the curated Hub Proteins Protein-Protein Interactions dataset. |
EGFR Gene SetFrom KEA Substrates of Kinases substrates of the kinase EGFR from the curated KEA Substrates of Kinases dataset. |
EGFR Gene SetFrom MSigDB Cancer Gene Co-expression Modules co-expressed genes for EGFR from the MSigDB Cancer Gene Co-expression Modules dataset. |
BL1585 (EGFR) Gene Setproteins in the BL1585 (EGFR) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
EPI-1114-1 (EGFR) Gene Setproteins in the EPI-1114-1 (EGFR) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
BL1586 (EGFR) Gene Setproteins in the BL1586 (EGFR) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
EGFR Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for EGFR from the Pathway Commons Protein-Protein Interactions dataset. |
egfr Gene SetFrom Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term egfr in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset. |
EGFR Gene SetFrom PhosphoSitePlus Substrates of Kinases substrates of the kinase EGFR from the curated PhosphoSitePlus Substrates of Kinases dataset. |
EGFR-dependent Endothelin signaling events Gene SetFrom PID Pathways proteins participating in the EGFR-dependent Endothelin signaling events pathway from the PID Pathways dataset. |
Signaling by Ligand-Responsive EGFR Variants in Cancer Gene Setproteins participating in the Signaling by Ligand-Responsive EGFR Variants in Cancer pathway from the Reactome Pathways dataset. |
EGFR interacts with phospholipase C-gamma Gene Setproteins participating in the EGFR interacts with phospholipase C-gamma pathway from the Reactome Pathways dataset. |
EGFR Transactivation by Gastrin Gene Setproteins participating in the EGFR Transactivation by Gastrin pathway from the Reactome Pathways dataset. |
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Gene Setproteins participating in the Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants pathway from the Reactome Pathways dataset. |
SHC1 events in EGFR signaling Gene Setproteins participating in the SHC1 events in EGFR signaling pathway from the Reactome Pathways dataset. |
GRB2 events in EGFR signaling Gene Setproteins participating in the GRB2 events in EGFR signaling pathway from the Reactome Pathways dataset. |
Inhibition of Signaling by Overexpressed EGFR Gene Setproteins participating in the Inhibition of Signaling by Overexpressed EGFR pathway from the Reactome Pathways dataset. |
Signaling by Overexpressed Wild-Type EGFR in Cancer Gene Setproteins participating in the Signaling by Overexpressed Wild-Type EGFR in Cancer pathway from the Reactome Pathways dataset. |
Signaling by EGFR in Cancer Gene Setproteins participating in the Signaling by EGFR in Cancer pathway from the Reactome Pathways dataset. |
Signaling by EGFR Gene Setproteins participating in the Signaling by EGFR pathway from the Reactome Pathways dataset. |
EGF/EGFR Signaling Pathway(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the EGF/EGFR Signaling Pathway(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
ERBB2-EGFR signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the ERBB2-EGFR signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
Shc-EGFR complex Gene SetFrom GO Cellular Component Annotations 2023 proteins localized to the Shc-EGFR complex cellular component from the curated GO Cellular Component Annotations 2023 dataset. |
Grb2-EGFR complex Gene SetFrom GO Cellular Component Annotations 2023 proteins localized to the Grb2-EGFR complex cellular component from the curated GO Cellular Component Annotations 2023 dataset. |
EGFR Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the EGFR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
EGFR Gene SetFrom Kinase Library Tyrosine Kinome Atlas substrates of the kinase EGFR from the Kinase Library Tyrosine Kinome Atlas dataset. |
RIOK1 and RIOK2 in EGFR and PI3K mediated tumorigenesis Gene SetFrom WikiPathways Pathways 2024 proteins participating in the RIOK1 and RIOK2 in EGFR and PI3K mediated tumorigenesis pathway from the WikiPathways Pathways 2024 dataset. |
EGF EGFR signaling Gene SetFrom WikiPathways Pathways 2024 proteins participating in the EGF EGFR signaling pathway from the WikiPathways Pathways 2024 dataset. |
Relationship between inflammation COX 2 and EGFR Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Relationship between inflammation COX 2 and EGFR pathway from the WikiPathways Pathways 2024 dataset. |
EGFR tyrosine kinase inhibitor resistance Gene SetFrom WikiPathways Pathways 2024 proteins participating in the EGFR tyrosine kinase inhibitor resistance pathway from the WikiPathways Pathways 2024 dataset. |
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Gene Setproteins participating in the Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants pathway from the Reactome Pathways 2024 dataset. |
EGFR Transactivation by Gastrin Gene Setproteins participating in the EGFR Transactivation by Gastrin pathway from the Reactome Pathways 2024 dataset. |
EGFR interacts with phospholipase C-gamma Gene Setproteins participating in the EGFR interacts with phospholipase C-gamma pathway from the Reactome Pathways 2024 dataset. |
GRB2 events in EGFR signaling Gene Setproteins participating in the GRB2 events in EGFR signaling pathway from the Reactome Pathways 2024 dataset. |
Inhibition of Signaling by Overexpressed EGFR Gene Setproteins participating in the Inhibition of Signaling by Overexpressed EGFR pathway from the Reactome Pathways 2024 dataset. |
SHC1 events in EGFR signaling Gene Setproteins participating in the SHC1 events in EGFR signaling pathway from the Reactome Pathways 2024 dataset. |
Signaling by EGFR Gene Setproteins participating in the Signaling by EGFR pathway from the Reactome Pathways 2024 dataset. |
Signaling by EGFR in Cancer Gene Setproteins participating in the Signaling by EGFR in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by Ligand-Responsive EGFR Variants in Cancer Gene Setproteins participating in the Signaling by Ligand-Responsive EGFR Variants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by Overexpressed Wild-Type EGFR in Cancer Gene Setproteins participating in the Signaling by Overexpressed Wild-Type EGFR in Cancer pathway from the Reactome Pathways 2024 dataset. |
ERBB2-EGFR signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the ERBB2-EGFR signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
Shc-EGFR complex Gene SetFrom GO Cellular Component Annotations 2025 proteins localized to the Shc-EGFR complex cellular component from the curated GO Cellular Component Annotations 2025 dataset. |
Grb2-EGFR complex Gene SetFrom GO Cellular Component Annotations 2025 proteins localized to the Grb2-EGFR complex cellular component from the curated GO Cellular Component Annotations 2025 dataset. |
Grb2-EGFR complex Gene SetFrom COMPARTMENTS Curated Protein Localization Evidence Scores 2025 proteins localized to the Grb2-EGFR complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. |
Shc-EGFR complex Gene SetFrom COMPARTMENTS Curated Protein Localization Evidence Scores 2025 proteins localized to the Shc-EGFR complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. |
ERBB4-EGFR complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the ERBB4-EGFR complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
Grb2-EGFR complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Grb2-EGFR complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
EGFR-Shc-Grb2-Sos complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the EGFR-Shc-Grb2-Sos complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
alphaV-beta3 integrin-EGFR complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the alphaV-beta3 integrin-EGFR complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
Shc-EGFR complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Shc-EGFR complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
EGFR:ERBB2 complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the EGFR:ERBB2 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
EGFR-Grb2-Sos complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the EGFR-Grb2-Sos complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
EGFR-related lung cancer Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the EGFR-related lung cancer phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
EGFR mutation-positive lung adenocarcinoma Gene SetFrom GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the EGFR mutation-positive lung adenocarcinoma phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. |
Chronic kidney disease (reduced eGFR or end stage renal disease) in type 1 diabetes Gene SetFrom GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the Chronic kidney disease (reduced eGFR or end stage renal disease) in type 1 diabetes phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. |
Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes Gene SetFrom GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the Chronic kidney disease (end stage renal disease vs. normal eGFR) in type 1 diabetes phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. |
Kidney disease (reduced eGFR and albuminuria or end stage renal disease) in type 1 diabetes Gene SetFrom GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the Kidney disease (reduced eGFR and albuminuria or end stage renal disease) in type 1 diabetes phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. |
ANTI-EGFR MONOCLONAL ANTIBODY EMD 55900 Gene Setinteracting proteins for the ANTI-EGFR MONOCLONAL ANTIBODY EMD 55900 drug from theDGIdb Drug Targets 2026 dataset. |
ANTI-EGFR MONOCLONAL ANTIBODY GT-MAB 5.2-GEX Gene Setinteracting proteins for the ANTI-EGFR MONOCLONAL ANTIBODY GT-MAB 5.2-GEX drug from theDGIdb Drug Targets 2026 dataset. |
ANTI-EGFR MONOCLONAL ANTIBODY SYN004 Gene Setinteracting proteins for the ANTI-EGFR MONOCLONAL ANTIBODY SYN004 drug from theDGIdb Drug Targets 2026 dataset. |
ANTI-EGFR/HER2/HER3 MONOCLONAL ANTIBODY MIXTURE SYM013 Gene Setinteracting proteins for the ANTI-EGFR/HER2/HER3 MONOCLONAL ANTIBODY MIXTURE SYM013 drug from theDGIdb Drug Targets 2026 dataset. |
ANTI-MET/EGFR MONOCLONAL ANTIBODY LY3164530 Gene Setinteracting proteins for the ANTI-MET/EGFR MONOCLONAL ANTIBODY LY3164530 drug from theDGIdb Drug Targets 2026 dataset. |
EGFR INHIBITOR Gene Setinteracting proteins for the EGFR INHIBITOR drug from theDGIdb Drug Targets 2026 dataset. |
EGFR INHIBITOR 57 Gene Setinteracting proteins for the EGFR INHIBITOR 57 drug from theDGIdb Drug Targets 2026 dataset. |
EGFR/ERBB-2 INHIBITOR Gene Setinteracting proteins for the EGFR/ERBB-2 INHIBITOR drug from theDGIdb Drug Targets 2026 dataset. |
EGFR/ERBB-2/ERBB-4 INHIBITOR Gene Setinteracting proteins for the EGFR/ERBB-2/ERBB-4 INHIBITOR drug from theDGIdb Drug Targets 2026 dataset. |
ANTI-EGFR MONOCLONAL ANTIBODY Gene Setinteracting proteins for the ANTI-EGFR MONOCLONAL ANTIBODY drug from theDGIdb Drug Targets 2026 dataset. |
