| Name |
|---|
MTOR Genemechanistic target of rapamycin (serine/threonine kinase) The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Inhibitors of mTOR are used in organ transplants as immunosuppressants, and are being evaluated for their therapeutic potential in SARS-CoV-2 infections. Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Aug 2020] |
MTOR-AS1 GeneMTOR antisense RNA 1 |
RICTOR GeneRPTOR independent companion of MTOR, complex 2 RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008] |
LAMTOR3P1 Genelate endosomal/lysosomal adaptor, MAPK and MTOR activator 3 pseudogene 1 |
MLST8 GeneMTOR associated protein, LST8 homolog (S. cerevisiae) Enables protein serine/threonine kinase activator activity and protein-macromolecule adaptor activity. Involved in TOR signaling; positive regulation of TOR signaling; and regulation of actin cytoskeleton organization. Part of TORC1 complex and TORC2 complex. [provided by Alliance of Genome Resources, Mar 2025] |
RPTOR Generegulatory associated protein of MTOR, complex 1 This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
LAMTOR3P2 Genelate endosomal/lysosomal adaptor, MAPK and MTOR activator 3 pseudogene 2 |
DEPTOR GeneDEP domain containing MTOR-interacting protein Enables phosphatidic acid binding activity and protein serine/threonine kinase inhibitor activity. Involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. Is active in lysosomal membrane. [provided by Alliance of Genome Resources, Mar 2025] |
LAMTOR4 Genelate endosomal/lysosomal adaptor, MAPK and MTOR activator 4 Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cellular response to amino acid stimulus; positive regulation of TORC1 signaling; and protein localization to lysosome. Located in lysosome. Part of FNIP-folliculin RagC/D GAP and Ragulator complex. Is active in lysosomal membrane. [provided by Alliance of Genome Resources, Mar 2025] |
LAMTOR5 Genelate endosomal/lysosomal adaptor, MAPK and MTOR activator 5 This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus. [provided by RefSeq, Jul 2008] |
LAMTOR1 Genelate endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Enables GTPase binding activity and protein-membrane adaptor activity. Contributes to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of TORC1 signaling; and regulation of cholesterol transport. Located in lysosome. Part of FNIP-folliculin RagC/D GAP. Is active in Ragulator complex and lysosomal membrane. [provided by Alliance of Genome Resources, Mar 2025] |
LAMTOR2 Genelate endosomal/lysosomal adaptor, MAPK and MTOR activator 2 The product of this gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The mouse protein interacts with MAPK scaffold protein 1, a component of the mitogen-activated protein kinase pathway. In humans, a mutation in this gene has been associated with a primary immunodeficiency syndrome, and suggests a role for this protein in endosomal biogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] |
LAMTOR3 Genelate endosomal/lysosomal adaptor, MAPK and MTOR activator 3 This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011] |
MEAK7 GeneMTOR associated protein, eak-7 homolog Involved in several processes, including TOR signaling; positive regulation of protein localization to lysosome; and response to insulin. Located in cytosol; lysosomal membrane; and nuclear lumen. [provided by Alliance of Genome Resources, Mar 2025] |
mTOR signalling Gene Setproteins participating in the mTOR signalling pathway from the Reactome Pathways dataset. |
MTOR signalling Gene Setproteins participating in the MTOR signalling pathway from the Reactome Pathways 2024 dataset. |
mTOR-signaling complex (FRAP1/mTOR, GBL, RAPTOR) Gene Setproteins in the mTOR-signaling complex (FRAP1/mTOR, GBL, RAPTOR) protein complex from the CORUM Protein Complexes dataset. |
mTOR-signaling complex (mTOR/FRAP1, RAPTOR) Gene Setproteins in the mTOR-signaling complex (mTOR/FRAP1, RAPTOR) protein complex from the CORUM Protein Complexes dataset. |
mtor signaling pathway Gene SetFrom Biocarta Pathways proteins participating in the mtor signaling pathway pathway from the Biocarta Pathways dataset. |
skeletal muscle hypertrophy is regulated via akt-mtor pathway Gene SetFrom Biocarta Pathways proteins participating in the skeletal muscle hypertrophy is regulated via akt-mtor pathway pathway from the Biocarta Pathways dataset. |
RICTOR-mTOR complex Gene Setproteins in the RICTOR-mTOR complex protein complex from the CORUM Protein Complexes dataset. |
mTOR-RICTOR complex Gene Setproteins in the mTOR-RICTOR complex protein complex from the CORUM Protein Complexes dataset. |
RAPTOR-mTOR complex Gene Setproteins in the RAPTOR-mTOR complex protein complex from the CORUM Protein Complexes dataset. |
mTOR-RAPTOR complex Gene Setproteins in the mTOR-RAPTOR complex protein complex from the CORUM Protein Complexes dataset. |
mTORC2 complex (mTOR/FRAP1, LST8, mAVO3/RICTOR) Gene Setproteins in the mTORC2 complex (mTOR/FRAP1, LST8, mAVO3/RICTOR) protein complex from the CORUM Protein Complexes dataset. |
mTOR-signaling complex Gene Setproteins in the mTOR-signaling complex protein complex from the CORUM Protein Complexes dataset. |
mTORC1 complex (mTOR/FRAP1, LST8, RAPTOR) Gene Setproteins in the mTORC1 complex (mTOR/FRAP1, LST8, RAPTOR) protein complex from the CORUM Protein Complexes dataset. |
mTORC2 complex (mTOR/FRAP1, LST8, mAVO3/RICTOR, SIN1) Gene Setproteins in the mTORC2 complex (mTOR/FRAP1, LST8, mAVO3/RICTOR, SIN1) protein complex from the CORUM Protein Complexes dataset. |
mtor Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term mtor in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Response to mTOR inhibitor (rapamycin) Gene SetFrom GWAS Catalog SNP-Phenotype Associations genes associated with the Response to mTOR inhibitor (rapamycin) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset. |
Response to mTOR inhibitor (everolimus) Gene SetFrom GWAS Catalog SNP-Phenotype Associations genes associated with the Response to mTOR inhibitor (everolimus) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset. |
MTOR Gene SetFrom Hub Proteins Protein-Protein Interactions interacting proteins for hub protein MTOR from the curated Hub Proteins Protein-Protein Interactions dataset. |
Rapamycin-insensitive companion of mTOR, N-terminal domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Rapamycin-insensitive companion of mTOR, N-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Rapamycin-insensitive companion of mTOR, phosphorylation-site Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Rapamycin-insensitive companion of mTOR, phosphorylation-site protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Rapamycin-insensitive companion of mTOR, domain 4 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Rapamycin-insensitive companion of mTOR, domain 4 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Rapamycin-insensitive companion of mTOR, domain 5 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Rapamycin-insensitive companion of mTOR, domain 5 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Rapamycin-insensitive companion of mTOR, middle domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Rapamycin-insensitive companion of mTOR, middle domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
MTOR Gene SetFrom KEA Substrates of Kinases substrates of the kinase MTOR from the curated KEA Substrates of Kinases dataset. |
mtor signaling pathway Gene SetFrom KEGG Pathways proteins participating in the mtor signaling pathway pathway from the KEGG Pathways dataset. |
BL4774 (MTOR) Gene Setproteins in the BL4774 (MTOR) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
BL897 (MTOR) Gene Setproteins in the BL897 (MTOR) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
BL4773 (MTOR) Gene Setproteins in the BL4773 (MTOR) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
MTOR Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for MTOR from the Pathway Commons Protein-Protein Interactions dataset. |
mtor Gene SetFrom Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term mtor in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset. |
MTOR Gene SetFrom PhosphoSitePlus Substrates of Kinases substrates of the kinase MTOR from the curated PhosphoSitePlus Substrates of Kinases dataset. |
mTOR signaling pathway Gene SetFrom PID Pathways proteins participating in the mTOR signaling pathway pathway from the PID Pathways dataset. |
Energy dependent regulation of mTOR by LKB1-AMPK Gene Setproteins participating in the Energy dependent regulation of mTOR by LKB1-AMPK pathway from the Reactome Pathways dataset. |
MTOR Gene SetFrom Kinase Library Serine Threonine Kinome Atlas substrates of the kinase MTOR from the Kinase Library Serine Threonine Kinome Atlas dataset. |
MTOR Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the MTOR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
PI3K AKT mTOR signaling and therapeutic opportunities in prostate cancer Gene SetFrom WikiPathways Pathways 2024 proteins participating in the PI3K AKT mTOR signaling and therapeutic opportunities in prostate cancer pathway from the WikiPathways Pathways 2024 dataset. |
Focal adhesion PI3K Akt mTOR signaling Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Focal adhesion PI3K Akt mTOR signaling pathway from the WikiPathways Pathways 2024 dataset. |
PI3K AKT mTOR vitamin D3 signaling Gene SetFrom WikiPathways Pathways 2024 proteins participating in the PI3K AKT mTOR vitamin D3 signaling pathway from the WikiPathways Pathways 2024 dataset. |
Modulation of PI3K Akt mTOR signaling by bioactive sphingolipids Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Modulation of PI3K Akt mTOR signaling by bioactive sphingolipids pathway from the WikiPathways Pathways 2024 dataset. |
Energy dependent regulation of mTOR by LKB1-AMPK Gene Setproteins participating in the Energy dependent regulation of mTOR by LKB1-AMPK pathway from the Reactome Pathways 2024 dataset. |
Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
MTOR-related megalencephaly and pigmentary mosaicism in skin Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the MTOR-related megalencephaly and pigmentary mosaicism in skin phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
Response to mTOR inhibitor (everolimus) Gene SetFrom GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the Response to mTOR inhibitor (everolimus) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. |
Response to mTOR inhibitor (rapamycin) Gene SetFrom GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the Response to mTOR inhibitor (rapamycin) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. |
mTOR signaling pathway Gene SetFrom KEGG Pathways 2026 proteins participating in the mTOR signaling pathway pathway from the KEGG Pathways 2026 dataset. |
MTOR INHIBITOR Gene Setinteracting proteins for the MTOR INHIBITOR drug from theDGIdb Drug Targets 2026 dataset. |
MTOR KINASE INHIBITOR AZD8055 Gene Setinteracting proteins for the MTOR KINASE INHIBITOR AZD8055 drug from theDGIdb Drug Targets 2026 dataset. |
MTOR KINASE INHIBITOR PP242 Gene Setinteracting proteins for the MTOR KINASE INHIBITOR PP242 drug from theDGIdb Drug Targets 2026 dataset. |
PI3K/MTOR KINASE INHIBITOR WXFL10030390 Gene Setinteracting proteins for the PI3K/MTOR KINASE INHIBITOR WXFL10030390 drug from theDGIdb Drug Targets 2026 dataset. |
PMC5811220-NIHMS939330-supplement-Supplemental_Table_4.xlsx-mTOR_repressed_AA_mRNAs_txt-mTOR-repressed_mRNAs_with_functions_in_AA_metabolism_and_transport_MSIGDB_M11769_M19056_M456_TEAD1 Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC5811220-NIHMS939330-supplement-Supplemental_Table_4.xlsx-mTOR_repressed_AA_mRNAs_txt-mTOR-repressed_mRNAs_with_functions_in_AA_metabolism_and_transport_MSIGDB_M11769_M19056_M456_TEAD1 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
phospholipids as signalling intermediaries Gene SetFrom Biocarta Pathways proteins participating in the phospholipids as signalling intermediaries pathway from the Biocarta Pathways dataset. |
wnt lrp6 signalling Gene SetFrom Biocarta Pathways proteins participating in the wnt lrp6 signalling pathway from the Biocarta Pathways dataset. |
P2X7 receptor signalling complex Gene Setproteins in the P2X7 receptor signalling complex protein complex from the CORUM Protein Complexes dataset. |
signalling Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term signalling in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
BMP Signalling Pathway Gene SetFrom HumanCyc Pathways proteins participating in the BMP Signalling Pathway pathway from the HumanCyc Pathways dataset. |
Suppressor of cytokine signalling Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Suppressor of cytokine signalling protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
NO signalling/Golgi transport ligand-binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the NO signalling/Golgi transport ligand-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Suppressor of cytokine signalling 6 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Suppressor of cytokine signalling 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Suppressor of cytokine signalling 7 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Suppressor of cytokine signalling 7 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Suppressor of cytokine signalling 4 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Suppressor of cytokine signalling 4 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Suppressor of cytokine signalling 5 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Suppressor of cytokine signalling 5 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Suppressor of cytokine signalling 2 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Suppressor of cytokine signalling 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Suppressor of cytokine signalling 3 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Suppressor of cytokine signalling 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Suppressor of cytokine signalling 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Suppressor of cytokine signalling 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
G-protein-signalling modulator 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the G-protein-signalling modulator 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
G-protein-signalling modulator 3 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the G-protein-signalling modulator 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Regulator of G-protein signalling 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Regulator of G-protein signalling 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
CD3 signalling complex delta subunit Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the CD3 signalling complex delta subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Hedgehog, N-terminal signalling domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Hedgehog, N-terminal signalling domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Regulator of G protein signalling-like domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Regulator of G protein signalling-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
SRC kinase signalling inhibitor 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the SRC kinase signalling inhibitor 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Signalling lymphocyte activation molecule family receptors Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Signalling lymphocyte activation molecule family receptors protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Phosphorylated immunoreceptor signalling ITAM Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Phosphorylated immunoreceptor signalling ITAM protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Hedgehog signalling/DD-peptidase zinc-binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Hedgehog signalling/DD-peptidase zinc-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Mitochondrial antiviral-signalling protein Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Mitochondrial antiviral-signalling protein protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Regulator of G-protein signalling 9-binding protein Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Regulator of G-protein signalling 9-binding protein protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Integrin signalling pathway Gene SetFrom PANTHER Pathways proteins participating in the Integrin signalling pathway pathway from the PANTHER Pathways dataset. |
Cell death signalling via NRAGE, NRIF and NADE Gene Setproteins participating in the Cell death signalling via NRAGE, NRIF and NADE pathway from the Reactome Pathways dataset. |
G beta:gamma signalling through PLC beta Gene Setproteins participating in the G beta:gamma signalling through PLC beta pathway from the Reactome Pathways dataset. |
Retrograde neurotrophin signalling Gene Setproteins participating in the Retrograde neurotrophin signalling pathway from the Reactome Pathways dataset. |
Thromboxane signalling through TP receptor Gene Setproteins participating in the Thromboxane signalling through TP receptor pathway from the Reactome Pathways dataset. |
PLC-gamma1 signalling Gene Setproteins participating in the PLC-gamma1 signalling pathway from the Reactome Pathways dataset. |
Ceramide signalling Gene Setproteins participating in the Ceramide signalling pathway from the Reactome Pathways dataset. |
Activated TLR4 signalling Gene Setproteins participating in the Activated TLR4 signalling pathway from the Reactome Pathways dataset. |
IRS-mediated signalling Gene Setproteins participating in the IRS-mediated signalling pathway from the Reactome Pathways dataset. |
Death Receptor Signalling Gene Setproteins participating in the Death Receptor Signalling pathway from the Reactome Pathways dataset. |
Signalling to RAS Gene Setproteins participating in the Signalling to RAS pathway from the Reactome Pathways dataset. |
G beta:gamma signalling through PI3Kgamma Gene Setproteins participating in the G beta:gamma signalling through PI3Kgamma pathway from the Reactome Pathways dataset. |
Prostacyclin signalling through prostacyclin receptor Gene Setproteins participating in the Prostacyclin signalling through prostacyclin receptor pathway from the Reactome Pathways dataset. |
SOS-mediated signalling Gene Setproteins participating in the SOS-mediated signalling pathway from the Reactome Pathways dataset. |
Opioid Signalling Gene Setproteins participating in the Opioid Signalling pathway from the Reactome Pathways dataset. |
G alpha (12/13) signalling events Gene Setproteins participating in the G alpha (12/13) signalling events pathway from the Reactome Pathways dataset. |
Thrombin signalling through proteinase activated receptors (PARs) Gene Setproteins participating in the Thrombin signalling through proteinase activated receptors (PARs) pathway from the Reactome Pathways dataset. |
Signalling by NGF Gene Setproteins participating in the Signalling by NGF pathway from the Reactome Pathways dataset. |
p75 NTR receptor-mediated signalling Gene Setproteins participating in the p75 NTR receptor-mediated signalling pathway from the Reactome Pathways dataset. |
PDE3B signalling Gene Setproteins participating in the PDE3B signalling pathway from the Reactome Pathways dataset. |
GP1b-IX-V activation signalling Gene Setproteins participating in the GP1b-IX-V activation signalling pathway from the Reactome Pathways dataset. |
Signalling to ERKs Gene Setproteins participating in the Signalling to ERKs pathway from the Reactome Pathways dataset. |
p75NTR recruits signalling complexes Gene Setproteins participating in the p75NTR recruits signalling complexes pathway from the Reactome Pathways dataset. |
Signalling to ERK5 Gene Setproteins participating in the Signalling to ERK5 pathway from the Reactome Pathways dataset. |
S6K1 signalling Gene Setproteins participating in the S6K1 signalling pathway from the Reactome Pathways dataset. |
G alpha (z) signalling events Gene Setproteins participating in the G alpha (z) signalling events pathway from the Reactome Pathways dataset. |
Rap1 signalling Gene Setproteins participating in the Rap1 signalling pathway from the Reactome Pathways dataset. |
ADP signalling through P2Y purinoceptor 12 Gene Setproteins participating in the ADP signalling through P2Y purinoceptor 12 pathway from the Reactome Pathways dataset. |
Signalling to STAT3 Gene Setproteins participating in the Signalling to STAT3 pathway from the Reactome Pathways dataset. |
NGF signalling via TRKA from the plasma membrane Gene Setproteins participating in the NGF signalling via TRKA from the plasma membrane pathway from the Reactome Pathways dataset. |
G alpha (s) signalling events Gene Setproteins participating in the G alpha (s) signalling events pathway from the Reactome Pathways dataset. |
PKA activation in glucagon signalling Gene Setproteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways dataset. |
ADP signalling through P2Y purinoceptor 1 Gene Setproteins participating in the ADP signalling through P2Y purinoceptor 1 pathway from the Reactome Pathways dataset. |
Gastrin-CREB signalling pathway via PKC and MAPK Gene Setproteins participating in the Gastrin-CREB signalling pathway via PKC and MAPK pathway from the Reactome Pathways dataset. |
Insulin receptor signalling cascade Gene Setproteins participating in the Insulin receptor signalling cascade pathway from the Reactome Pathways dataset. |
G alpha (i) signalling events Gene Setproteins participating in the G alpha (i) signalling events pathway from the Reactome Pathways dataset. |
NADE modulates death signalling Gene Setproteins participating in the NADE modulates death signalling pathway from the Reactome Pathways dataset. |
SHC-mediated signalling Gene Setproteins participating in the SHC-mediated signalling pathway from the Reactome Pathways dataset. |
S6K1-mediated signalling Gene Setproteins participating in the S6K1-mediated signalling pathway from the Reactome Pathways dataset. |
Signalling to p38 via RIT and RIN Gene Setproteins participating in the Signalling to p38 via RIT and RIN pathway from the Reactome Pathways dataset. |
G-protein beta:gamma signalling Gene Setproteins participating in the G-protein beta:gamma signalling pathway from the Reactome Pathways dataset. |
Adrenaline signalling through Alpha-2 adrenergic receptor Gene Setproteins participating in the Adrenaline signalling through Alpha-2 adrenergic receptor pathway from the Reactome Pathways dataset. |
mTORC1-mediated signalling Gene Setproteins participating in the mTORC1-mediated signalling pathway from the Reactome Pathways dataset. |
G alpha (q) signalling events Gene Setproteins participating in the G alpha (q) signalling events pathway from the Reactome Pathways dataset. |
SREBP signalling(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the SREBP signalling(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
Estrogen signalling(Mus musculus) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Estrogen signalling(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset. |
BMP Signalling and Regulation(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the BMP Signalling and Regulation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
trans-synaptic signalling via exosome Gene SetFrom SynGO Synaptic Gene Annotations genes associated with the synaptic term trans-synaptic signalling via exosome from the SynGO Synaptic Gene Annotations dataset. |
ADP signalling through P2Y purinoceptor 1 Gene Setproteins participating in the ADP signalling through P2Y purinoceptor 1 pathway from the Reactome Pathways 2024 dataset. |
ADP signalling through P2Y purinoceptor 12 Gene Setproteins participating in the ADP signalling through P2Y purinoceptor 12 pathway from the Reactome Pathways 2024 dataset. |
Adrenaline signalling through Alpha-2 adrenergic receptor Gene Setproteins participating in the Adrenaline signalling through Alpha-2 adrenergic receptor pathway from the Reactome Pathways 2024 dataset. |
Aryl hydrocarbon receptor signalling Gene Setproteins participating in the Aryl hydrocarbon receptor signalling pathway from the Reactome Pathways 2024 dataset. |
Caspase activation via extrinsic apoptotic signalling pathway Gene Setproteins participating in the Caspase activation via extrinsic apoptotic signalling pathway pathway from the Reactome Pathways 2024 dataset. |
Cell death signalling via NRAGE, NRIF and NADE Gene Setproteins participating in the Cell death signalling via NRAGE, NRIF and NADE pathway from the Reactome Pathways 2024 dataset. |
Ceramide signalling Gene Setproteins participating in the Ceramide signalling pathway from the Reactome Pathways 2024 dataset. |
G alpha (12/13) signalling events Gene Setproteins participating in the G alpha (12/13) signalling events pathway from the Reactome Pathways 2024 dataset. |
G alpha (i) signalling events Gene Setproteins participating in the G alpha (i) signalling events pathway from the Reactome Pathways 2024 dataset. |
G alpha (q) signalling events Gene Setproteins participating in the G alpha (q) signalling events pathway from the Reactome Pathways 2024 dataset. |
G alpha (s) signalling events Gene Setproteins participating in the G alpha (s) signalling events pathway from the Reactome Pathways 2024 dataset. |
G alpha (z) signalling events Gene Setproteins participating in the G alpha (z) signalling events pathway from the Reactome Pathways 2024 dataset. |
G beta:gamma signalling through BTK Gene Setproteins participating in the G beta:gamma signalling through BTK pathway from the Reactome Pathways 2024 dataset. |
G beta:gamma signalling through CDC42 Gene Setproteins participating in the G beta:gamma signalling through CDC42 pathway from the Reactome Pathways 2024 dataset. |
G beta:gamma signalling through PI3Kgamma Gene Setproteins participating in the G beta:gamma signalling through PI3Kgamma pathway from the Reactome Pathways 2024 dataset. |
G beta:gamma signalling through PLC beta Gene Setproteins participating in the G beta:gamma signalling through PLC beta pathway from the Reactome Pathways 2024 dataset. |
G-protein beta:gamma signalling Gene Setproteins participating in the G-protein beta:gamma signalling pathway from the Reactome Pathways 2024 dataset. |
GP1b-IX-V activation signalling Gene Setproteins participating in the GP1b-IX-V activation signalling pathway from the Reactome Pathways 2024 dataset. |
GPCR downstream signalling Gene Setproteins participating in the GPCR downstream signalling pathway from the Reactome Pathways 2024 dataset. |
Gastrin-CREB signalling pathway via PKC and MAPK Gene Setproteins participating in the Gastrin-CREB signalling pathway via PKC and MAPK pathway from the Reactome Pathways 2024 dataset. |
IRS-mediated signalling Gene Setproteins participating in the IRS-mediated signalling pathway from the Reactome Pathways 2024 dataset. |
Insulin receptor signalling cascade Gene Setproteins participating in the Insulin receptor signalling cascade pathway from the Reactome Pathways 2024 dataset. |
Interleukin-35 Signalling Gene Setproteins participating in the Interleukin-35 Signalling pathway from the Reactome Pathways 2024 dataset. |
NADE modulates death signalling Gene Setproteins participating in the NADE modulates death signalling pathway from the Reactome Pathways 2024 dataset. |
Opioid Signalling Gene Setproteins participating in the Opioid Signalling pathway from the Reactome Pathways 2024 dataset. |
PDE3B signalling Gene Setproteins participating in the PDE3B signalling pathway from the Reactome Pathways 2024 dataset. |
PKA activation in glucagon signalling Gene Setproteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways 2024 dataset. |
PLC-gamma1 signalling Gene Setproteins participating in the PLC-gamma1 signalling pathway from the Reactome Pathways 2024 dataset. |
Prostacyclin signalling through prostacyclin receptor Gene Setproteins participating in the Prostacyclin signalling through prostacyclin receptor pathway from the Reactome Pathways 2024 dataset. |
Rap1 signalling Gene Setproteins participating in the Rap1 signalling pathway from the Reactome Pathways 2024 dataset. |
Reelin signalling pathway Gene Setproteins participating in the Reelin signalling pathway pathway from the Reactome Pathways 2024 dataset. |
Retrograde neurotrophin signalling Gene Setproteins participating in the Retrograde neurotrophin signalling pathway from the Reactome Pathways 2024 dataset. |
SARS-CoV-1 targets host intracellular signalling and regulatory pathways Gene Setproteins participating in the SARS-CoV-1 targets host intracellular signalling and regulatory pathways pathway from the Reactome Pathways 2024 dataset. |
SARS-CoV-2 targets host intracellular signalling and regulatory pathways Gene Setproteins participating in the SARS-CoV-2 targets host intracellular signalling and regulatory pathways pathway from the Reactome Pathways 2024 dataset. |
SOS-mediated signalling Gene Setproteins participating in the SOS-mediated signalling pathway from the Reactome Pathways 2024 dataset. |
Signalling to ERK5 Gene Setproteins participating in the Signalling to ERK5 pathway from the Reactome Pathways 2024 dataset. |
Signalling to ERKs Gene Setproteins participating in the Signalling to ERKs pathway from the Reactome Pathways 2024 dataset. |
Signalling to RAS Gene Setproteins participating in the Signalling to RAS pathway from the Reactome Pathways 2024 dataset. |
Signalling to STAT3 Gene Setproteins participating in the Signalling to STAT3 pathway from the Reactome Pathways 2024 dataset. |
Signalling to p38 via RIT and RIN Gene Setproteins participating in the Signalling to p38 via RIT and RIN pathway from the Reactome Pathways 2024 dataset. |
Thrombin signalling through proteinase activated receptors (PARs) Gene Setproteins participating in the Thrombin signalling through proteinase activated receptors (PARs) pathway from the Reactome Pathways 2024 dataset. |
Thromboxane signalling through TP receptor Gene Setproteins participating in the Thromboxane signalling through TP receptor pathway from the Reactome Pathways 2024 dataset. |
mTORC1-mediated signalling Gene Setproteins participating in the mTORC1-mediated signalling pathway from the Reactome Pathways 2024 dataset. |
p75 NTR receptor-mediated signalling Gene Setproteins participating in the p75 NTR receptor-mediated signalling pathway from the Reactome Pathways 2024 dataset. |
p75NTR recruits signalling complexes Gene Setproteins participating in the p75NTR recruits signalling complexes pathway from the Reactome Pathways 2024 dataset. |