Name

CMAP Signatures of Differentially Expressed Genes for Small Molecules Dataset

From Connectivity Map

mRNA expression profiles for cell lines following chemical perturbation

ESCAPE Omics Signatures of Genes and Proteins for Stem Cells Dataset

From ESCAPE

Sets of target genes of transcription factors from published ChIP-chip, ChIP-seq, and other transcription factor binding site profiling studies;sets of differentially expressed genes following perturbation of a protein from gene expression data in GEO; sets of interacting proteins from high- and low-throughput protein-protein interaction studies; sets of targets of microRNAs from public databases, computationally predicted or experimentally verified

GEO Signatures of Differentially Expressed Genes for Diseases Dataset

From Gene Expression Omnibus

mRNA expression profiles for cell lines or tissues following disease perturbation

GEO Signatures of Differentially Expressed Genes for Gene Perturbations Dataset

From Gene Expression Omnibus

mRNA expression profiles for cell lines or tissues following genetic perturbation (knockdown, knockout, over-expression, mutation)

GEO Signatures of Differentially Expressed Genes for Kinase Perturbations Dataset

From Gene Expression Omnibus

mRNA expression profiles for cell lines or tissues following kinase perturbation (inhibition, activation, knockdown, knockout, over-expression, mutation)

GEO Signatures of Differentially Expressed Genes for Small Molecules Dataset

From Gene Expression Omnibus

mRNA expression profiles for cell lines or tissues following small molecule perturbation

GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations Dataset

From Gene Expression Omnibus

mRNA expression profiles for cell lines or tissues following transcription factor perturbation (inhibition, activation, knockdown, knockout, over-expression, mutation)

GEO Signatures of Differentially Expressed Genes for Viral Infections Dataset

From Gene Expression Omnibus

mRNA expression profiles for cell lines or tissues following viral infection

LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules Dataset (Archived)

From LINCS L1000 Connectivity Map

mRNA expression profiles for cell lines following small molecule perturbation

MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations Dataset

From Molecular Signatures Database

Oncogenic signatures of genes differentially expressed following cancer gene perturbations

TCGA Signatures of Differentially Expressed Genes for Tumors Dataset

From The Cancer Genome Atlas

mRNA expression profiles for tumor and normal tissue samples

PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations Dataset

From PerturbAtlas

Gene expression profiles for cell lines, cell types, tissues, and models following genetic perturbation (knockdown, knockout, knockin, over-expression, mutation, and multi-condition)

PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations Dataset

From PerturbAtlas

Gene expression profiles for cell lines, cell types, tissues, and models following genetic perturbation (knockdown, knockout, knockin, over-expression, mutation, and multi-condition)

KEGG Pathways Dataset (Archived)

From Kyoto Encyclopedia of Genes and Genomes

Sets of proteins participating in pathways from KEGG

KEGG Pathways 2026 Dataset

From Kyoto Encyclopedia of Genes and Genomes

Sets of proteins participating in pathways from KEGG

NFE2L2 Gene

nuclear factor, erythroid 2-like 2

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]

MARK4 Gene

MAP/microtubule affinity-regulating kinase 4

This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

MARK1 Gene

MAP/microtubule affinity-regulating kinase 1

Enables several functions, including ATP binding activity; magnesium ion binding activity; and phospholipid binding activity. Involved in intracellular signal transduction; negative regulation of epithelial to mesenchymal transition; and protein phosphorylation. Located in cytoplasm; dendrite; and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

MARK2 Gene

MAP/microtubule affinity-regulating kinase 2

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]

MARK3 Gene

MAP/microtubule affinity-regulating kinase 3

The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

RIMS4 Gene

regulating synaptic membrane exocytosis 4

Predicted to enable transmembrane transporter binding activity. Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in several processes, including regulation of synapse organization; regulation of synaptic vesicle exocytosis; and synaptic vesicle exocytosis. Predicted to be located in synaptic membrane. Predicted to be active in glutamatergic synapse; presynaptic active zone cytoplasmic component; and presynaptic membrane. [provided by Alliance of Genome Resources, Mar 2025]

RIMS1 Gene

regulating synaptic membrane exocytosis 1

The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]

RIMS2 Gene

regulating synaptic membrane exocytosis 2

The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017]

RIMS3 Gene

regulating synaptic membrane exocytosis 3

Predicted to enable transmembrane transporter binding activity. Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in several processes, including regulated exocytosis; regulation of synapse organization; and regulation of synaptic vesicle exocytosis. Predicted to be located in presynaptic active zone. Predicted to be active in several cellular components, including postsynaptic cytosol; presynaptic active zone cytoplasmic component; and presynaptic membrane. [provided by Alliance of Genome Resources, Mar 2025]

SIT1 Gene

signaling threshold regulating transmembrane adaptor 1

Enables kinase binding activity. Involved in regulation of T cell activation. Located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

LOC100421494 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

TRERF1 Gene

transcriptional regulating factor 1

This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

FLJ25758 Gene

MAP/microtubule affinity-regulating kinase 1 pseudogene

PHEX Gene

phosphate regulating endopeptidase homolog, X-linked

The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

MARK2P12 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 12

ADRM1 Gene

adhesion regulating molecule 1

This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

MARK2P8 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 8

MARK2P9 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 9

MARK2P4 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 4

MARK2P5 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 5

MARK2P6 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 6

MARK2P7 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 7

MARK2P1 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 1

MARK2P2 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 2

MARK2P3 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 3

LOC100421508 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

LOC100421505 Gene

MAP/microtubule affinity-regulating kinase 4 pseudogene

LOC100421558 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

ADTRP Gene

androgen-dependent TFPI-regulating protein

Enables hydrolase activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; negative regulation of secretion by cell; and positive regulation of macromolecule metabolic process. Located in caveola and cell surface. [provided by Alliance of Genome Resources, Mar 2025]

LOC100421504 Gene

MAP/microtubule affinity-regulating kinase 4 pseudogene

TP53RK Gene

TP53 regulating kinase

Enables p53 binding activity and protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in cytoplasm and nucleus. Part of EKC/KEOPS complex. Implicated in Galloway-Mowat syndrome 4. [provided by Alliance of Genome Resources, Mar 2025]

MARK2P16 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 16

MARK2P17 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 17

MARK2P14 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 14

MARK2P15 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 15

MARK2P13 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 13

MARK2P10 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 10

MARK2P11 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene 11

SERGEF Gene

secretion regulating guanine nucleotide exchange factor

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in negative regulation of protein secretion. Located in cytosol and nucleoplasm. Biomarker of atherosclerosis. [provided by Alliance of Genome Resources, Mar 2025]

MARK3P1 Gene

MAP/microtubule affinity-regulating kinase 3 pseudogene 1

MARK3P3 Gene

MAP/microtubule affinity-regulating kinase 3 pseudogene 3

MARK3P2 Gene

MAP/microtubule affinity-regulating kinase 3 pseudogene 2

LOC100533755 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

LOC100421511 Gene

MAP/microtubule affinity-regulating kinase 2 pseudogene

MYORG Gene

myogenesis regulating glycosidase (putative)

Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds. Involved in skeletal muscle fiber development. Predicted to be located in endoplasmic reticulum membrane and nuclear membrane. Implicated in basal ganglia calcification. [provided by Alliance of Genome Resources, Mar 2025]

MROCKI Gene

MARCKS cis regulating lncRNA promoter of cytokines and inflammation

TERLR1 Gene

TERT regulating lncRNA 1

NFE2L2 regulating tumorigenic genes Gene Set

From Reactome Pathways 2024

proteins participating in the NFE2L2 regulating tumorigenic genes pathway from the Reactome Pathways 2024 dataset.

NFE2L2 regulating ER-stress associated genes Gene Set

From Reactome Pathways 2024

proteins participating in the NFE2L2 regulating ER-stress associated genes pathway from the Reactome Pathways 2024 dataset.

NFE2L2 regulating TCA cycle genes Gene Set

From Reactome Pathways 2024

proteins participating in the NFE2L2 regulating TCA cycle genes pathway from the Reactome Pathways 2024 dataset.

NFE2L2 regulating inflammation associated genes Gene Set

From Reactome Pathways 2024

proteins participating in the NFE2L2 regulating inflammation associated genes pathway from the Reactome Pathways 2024 dataset.

NFE2L2 regulating MDR associated enzymes Gene Set

From Reactome Pathways 2024

proteins participating in the NFE2L2 regulating MDR associated enzymes pathway from the Reactome Pathways 2024 dataset.

NFE2L2 regulating anti-oxidant/detoxification enzymes Gene Set

From Reactome Pathways 2024

proteins participating in the NFE2L2 regulating anti-oxidant/detoxification enzymes pathway from the Reactome Pathways 2024 dataset.

NFE2L2 regulates pentose phosphate pathway genes Gene Set

From Reactome Pathways 2024

proteins participating in the NFE2L2 regulates pentose phosphate pathway genes pathway from the Reactome Pathways 2024 dataset.

tumorigenic Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tumorigenic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

regulating Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term regulating in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

immune response-regulating cell surface receptor signaling pathway involved in phagocytosis Gene Set

From GO Biological Process Annotations 2015

genes participating in the immune response-regulating cell surface receptor signaling pathway involved in phagocytosis biological process from the curated GO Biological Process Annotations 2015 dataset.

cellular process regulating host cell cycle in response to virus Gene Set

From GO Biological Process Annotations 2015

genes participating in the cellular process regulating host cell cycle in response to virus biological process from the curated GO Biological Process Annotations 2015 dataset.

immune response-regulating signaling pathway Gene Set

From GO Biological Process Annotations 2015

genes participating in the immune response-regulating signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

immune response-regulating cell surface receptor signaling pathway Gene Set

From GO Biological Process Annotations 2015

genes participating in the immune response-regulating cell surface receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

establishment or maintenance of cell polarity regulating cell shape Gene Set

From GO Biological Process Annotations 2015

genes participating in the establishment or maintenance of cell polarity regulating cell shape biological process from the curated GO Biological Process Annotations 2015 dataset.

Secretion-regulating guanine nucleotide exchange factor Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Secretion-regulating guanine nucleotide exchange factor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Role of DCC in regulating apoptosis Gene Set

From Reactome Pathways 2014

proteins participating in the Role of DCC in regulating apoptosis pathway from the Reactome Pathways dataset.

immune response-regulating cell surface receptor signaling pathway Gene Set

From GO Biological Process Annotations 2023

genes participating in the immune response-regulating cell surface receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Transcriptional cascade regulating adipogenesis Gene Set

From WikiPathways Pathways 2024

proteins participating in the Transcriptional cascade regulating adipogenesis pathway from the WikiPathways Pathways 2024 dataset.

immune response-regulating cell surface receptor signaling pathway Gene Set

From GO Biological Process Annotations 2025

genes participating in the immune response-regulating cell surface receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Signaling pathways regulating pluripotency of stem cells Gene Set

From KEGG Pathways 2026

proteins participating in the Signaling pathways regulating pluripotency of stem cells pathway from the KEGG Pathways 2026 dataset.

Longevity regulating pathway Gene Set

From KEGG Pathways 2026

proteins participating in the Longevity regulating pathway pathway from the KEGG Pathways 2026 dataset.

Longevity regulating pathway - multiple species Gene Set

From KEGG Pathways 2026

proteins participating in the Longevity regulating pathway - multiple species pathway from the KEGG Pathways 2026 dataset.

NFE2L2-22581777-LYMPHOBLASTOID-HUMAN Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the NFE2L2-22581777-LYMPHOBLASTOID-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

NFE2L2-20460467-MEF-MOUSE Gene Set

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the NFE2L2-20460467-MEF-MOUSE transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

NFE2L2 Gene Set

From ChEA Transcription Factor Targets

target genes of the NFE2L2 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

nfe2l2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nfe2l2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NFE2L2 Gene Set

From MotifMap Predicted Transcription Factor Targets

target genes of the NFE2L2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

NFE2L2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NFE2L2 from the Pathway Commons Protein-Protein Interactions dataset.

NFE2L2-22581777-LYMPHOBLASTOID-HUMAN Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the NFE2L2-22581777-LYMPHOBLASTOID-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

NFE2L2-20460467-MEFS-MOUSE Gene Set

From ChEA Transcription Factor Targets 2022

target genes of the NFE2L2-20460467-MEFS-MOUSE transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

NFE2L2 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the NFE2L2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

Photodynamic therapy induced NFE2L2 NRF2 survival signaling Gene Set

From WikiPathways Pathways 2024

proteins participating in the Photodynamic therapy induced NFE2L2 NRF2 survival signaling pathway from the WikiPathways Pathways 2024 dataset.

GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 Gene Set

From Reactome Pathways 2024

proteins participating in the GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 pathway from the Reactome Pathways 2024 dataset.

KEAP1-NFE2L2 pathway Gene Set

From Reactome Pathways 2024

proteins participating in the KEAP1-NFE2L2 pathway pathway from the Reactome Pathways 2024 dataset.

Nuclear events mediated by NFE2L2 Gene Set

From Reactome Pathways 2024

proteins participating in the Nuclear events mediated by NFE2L2 pathway from the Reactome Pathways 2024 dataset.

Regulation of NFE2L2 gene expression Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of NFE2L2 gene expression pathway from the Reactome Pathways 2024 dataset.

Nfe2l2 Gene Set

From JASPAR Predicted Mouse Transcription Factor Targets 2025

target genes of the Nfe2l2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2925 dataset.

PMC6772115-JCB-120-18332-s003.xlsx-NFE2L2-Dataset_Gene_ID_NFE2L2 Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC6772115-JCB-120-18332-s003.xlsx-NFE2L2-Dataset_Gene_ID_NFE2L2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC5309296-18_2016_2401_MOESM3_ESM.xlsx-NFE2L2-Unnamed_0_NFE2L2 Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC5309296-18_2016_2401_MOESM3_ESM.xlsx-NFE2L2-Unnamed_0_NFE2L2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

NFE2L2 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the NFE2L2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

gata3 participate in activating the th2 cytokine genes expression Gene Set

From Biocarta Pathways

proteins participating in the gata3 participate in activating the th2 cytokine genes expression pathway from the Biocarta Pathways dataset.

factor viii and factor ix genes Gene Set

From GAD Gene-Disease Associations

genes associated with the disease factor viii and factor ix genes in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

hla genes Gene Set

From GAD Gene-Disease Associations

genes associated with the disease hla genes in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

drug-related genes Gene Set

From GAD Gene-Disease Associations

genes associated with the disease drug-related genes in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

sickle cell and thalassaemia genes Gene Set

From GAD Gene-Disease Associations

genes associated with the disease sickle cell and thalassaemia genes in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

18387200-Genes Gene Set

From GeneSigDB Published Gene Signatures

genes in signature reported in the publication with PubMedID 18387200-Genes from the GeneSigDB Published Gene Signatures dataset.

18278552-Genes Gene Set

From GeneSigDB Published Gene Signatures

genes in signature reported in the publication with PubMedID 18278552-Genes from the GeneSigDB Published Gene Signatures dataset.

somatic recombination of immunoglobulin genes involved in immune response Gene Set

From GO Biological Process Annotations 2015

genes participating in the somatic recombination of immunoglobulin genes involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset.

somatic hypermutation of immunoglobulin genes Gene Set

From GO Biological Process Annotations 2015

genes participating in the somatic hypermutation of immunoglobulin genes biological process from the curated GO Biological Process Annotations 2015 dataset.

somatic diversification of t cell receptor genes Gene Set

From GO Biological Process Annotations 2015

genes participating in the somatic diversification of t cell receptor genes biological process from the curated GO Biological Process Annotations 2015 dataset.

Stimulator of interferon genes protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Stimulator of interferon genes protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Cellular repressor of E1A-stimulated genes (CREG) Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cellular repressor of E1A-stimulated genes (CREG) protein domain from the InterPro Predicted Protein Domain Annotations dataset.

ATF4 activates genes Gene Set

From Reactome Pathways 2014

proteins participating in the ATF4 activates genes pathway from the Reactome Pathways dataset.

Transcriptional activation of p53 responsive genes Gene Set

From Reactome Pathways 2014

proteins participating in the Transcriptional activation of p53 responsive genes pathway from the Reactome Pathways dataset.

GLI proteins bind promoters of Hh responsive genes to promote transcription Gene Set

From Reactome Pathways 2014

proteins participating in the GLI proteins bind promoters of Hh responsive genes to promote transcription pathway from the Reactome Pathways dataset.

XBP1(S) activates chaperone genes Gene Set

From Reactome Pathways 2014

proteins participating in the XBP1(S) activates chaperone genes pathway from the Reactome Pathways dataset.

POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Gene Set

From Reactome Pathways 2014

proteins participating in the POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation pathway from the Reactome Pathways dataset.

repression of WNT target genes Gene Set

From Reactome Pathways 2014

proteins participating in the repression of WNT target genes pathway from the Reactome Pathways dataset.

POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation Gene Set

From Reactome Pathways 2014

proteins participating in the POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation pathway from the Reactome Pathways dataset.

Antiviral mechanism by IFN-stimulated genes Gene Set

From Reactome Pathways 2014

proteins participating in the Antiviral mechanism by IFN-stimulated genes pathway from the Reactome Pathways dataset.

ATF6-alpha activates chaperone genes Gene Set

From Reactome Pathways 2014

proteins participating in the ATF6-alpha activates chaperone genes pathway from the Reactome Pathways dataset.

deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling Gene Set

From Reactome Pathways 2014

proteins participating in the deletions in the AXIN genes in hepatocellular carcinoma result in elevated WNT signaling pathway from the Reactome Pathways dataset.

Diurnally Regulated Genes with Circadian Orthologs(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Diurnally Regulated Genes with Circadian Orthologs(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

miR-targeted genes in lymphocytes - TarBase(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the miR-targeted genes in lymphocytes - TarBase(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

Adipogenesis genes(Mus musculus) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Adipogenesis genes(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

miR-targeted genes in adipocytes - TarBase(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the miR-targeted genes in adipocytes - TarBase(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

Ovarian Infertility Genes(Mus musculus) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Ovarian Infertility Genes(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

miR-targeted genes in muscle cell - TarBase(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the miR-targeted genes in muscle cell - TarBase(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

Deregulation of Rab and Rab Effector Genes in Bladder Cancer(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Deregulation of Rab and Rab Effector Genes in Bladder Cancer(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

Diurnally Regulated Genes with Circadian Orthologs(Mus musculus) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Diurnally Regulated Genes with Circadian Orthologs(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

RalA downstream regulated genes(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the RalA downstream regulated genes(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

miR-targeted genes in leukocytes - TarBase(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the miR-targeted genes in leukocytes - TarBase(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

miR-targeted genes in squamous cell - TarBase(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the miR-targeted genes in squamous cell - TarBase(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

Ovarian Infertility Genes(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Ovarian Infertility Genes(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

miR-targeted genes in epithelium - TarBase(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the miR-targeted genes in epithelium - TarBase(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

somatic hypermutation of immunoglobulin genes Gene Set

From GO Biological Process Annotations 2023

genes participating in the somatic hypermutation of immunoglobulin genes biological process from the curated GO Biological Process Annotations 2023 dataset.

maintenance of DNA methylation at imprinted genes Gene Set

From GO Biological Process Annotations 2023

genes participating in the maintenance of DNA methylation at imprinted genes biological process from the curated GO Biological Process Annotations 2023 dataset.

somatic recombination of immunoglobulin genes involved in immune response Gene Set

From GO Biological Process Annotations 2023

genes participating in the somatic recombination of immunoglobulin genes involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset.

Genes targeted by miRNAs in adipocytes Gene Set

From WikiPathways Pathways 2024

proteins participating in the Genes targeted by miRNAs in adipocytes pathway from the WikiPathways Pathways 2024 dataset.

RalA downstream regulated genes Gene Set

From WikiPathways Pathways 2024

proteins participating in the RalA downstream regulated genes pathway from the WikiPathways Pathways 2024 dataset.

Deregulation of Rab and Rab effector genes in bladder cancer Gene Set

From WikiPathways Pathways 2024

proteins participating in the Deregulation of Rab and Rab effector genes in bladder cancer pathway from the WikiPathways Pathways 2024 dataset.

Circadian rhythm genes Gene Set

From WikiPathways Pathways 2024

proteins participating in the Circadian rhythm genes pathway from the WikiPathways Pathways 2024 dataset.

Effect of progerin on genes involved in progeria Gene Set

From WikiPathways Pathways 2024

proteins participating in the Effect of progerin on genes involved in progeria pathway from the WikiPathways Pathways 2024 dataset.

Genes related to primary cilium development based on CRISPR Gene Set

From WikiPathways Pathways 2024

proteins participating in the Genes related to primary cilium development based on CRISPR pathway from the WikiPathways Pathways 2024 dataset.

Multiple epiphyseal dysplasia and pseudoachondroplasia genes Gene Set

From WikiPathways Pathways 2024

proteins participating in the Multiple epiphyseal dysplasia and pseudoachondroplasia genes pathway from the WikiPathways Pathways 2024 dataset.

Genes controlling nephrogenesis Gene Set

From WikiPathways Pathways 2024

proteins participating in the Genes controlling nephrogenesis pathway from the WikiPathways Pathways 2024 dataset.

Genes associated with the development of rheumatoid arthritis Gene Set

From WikiPathways Pathways 2024

proteins participating in the Genes associated with the development of rheumatoid arthritis pathway from the WikiPathways Pathways 2024 dataset.

ATF4 activates genes in response to endoplasmic reticulum stress Gene Set

From Reactome Pathways 2024

proteins participating in the ATF4 activates genes in response to endoplasmic reticulum stress pathway from the Reactome Pathways 2024 dataset.

ATF6 (ATF6-alpha) activates chaperone genes Gene Set

From Reactome Pathways 2024

proteins participating in the ATF6 (ATF6-alpha) activates chaperone genes pathway from the Reactome Pathways 2024 dataset.

Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 Gene Set

From Reactome Pathways 2024

proteins participating in the Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 pathway from the Reactome Pathways 2024 dataset.

Activation of HOX genes during differentiation Gene Set

From Reactome Pathways 2024

proteins participating in the Activation of HOX genes during differentiation pathway from the Reactome Pathways 2024 dataset.

Activation of anterior HOX genes in hindbrain development during early embryogenesis Gene Set

From Reactome Pathways 2024

proteins participating in the Activation of anterior HOX genes in hindbrain development during early embryogenesis pathway from the Reactome Pathways 2024 dataset.

Antiviral mechanism by IFN-stimulated genes Gene Set

From Reactome Pathways 2024

proteins participating in the Antiviral mechanism by IFN-stimulated genes pathway from the Reactome Pathways 2024 dataset.

CREB3 factors activate genes Gene Set

From Reactome Pathways 2024

proteins participating in the CREB3 factors activate genes pathway from the Reactome Pathways 2024 dataset.

Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes Gene Set

From Reactome Pathways 2024

proteins participating in the Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes pathway from the Reactome Pathways 2024 dataset.

FOXO-mediated transcription of cell cycle genes Gene Set

From Reactome Pathways 2024

proteins participating in the FOXO-mediated transcription of cell cycle genes pathway from the Reactome Pathways 2024 dataset.

FOXO-mediated transcription of cell death genes Gene Set

From Reactome Pathways 2024

proteins participating in the FOXO-mediated transcription of cell death genes pathway from the Reactome Pathways 2024 dataset.

FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Gene Set

From Reactome Pathways 2024

proteins participating in the FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes pathway from the Reactome Pathways 2024 dataset.

GLI proteins bind promoters of Hh responsive genes to promote transcription Gene Set

From Reactome Pathways 2024

proteins participating in the GLI proteins bind promoters of Hh responsive genes to promote transcription pathway from the Reactome Pathways 2024 dataset.

MECP2 regulates transcription of genes involved in GABA signaling Gene Set

From Reactome Pathways 2024

proteins participating in the MECP2 regulates transcription of genes involved in GABA signaling pathway from the Reactome Pathways 2024 dataset.

MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis Gene Set

From Reactome Pathways 2024

proteins participating in the MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis pathway from the Reactome Pathways 2024 dataset.

NPAS4 regulates expression of target genes Gene Set

From Reactome Pathways 2024

proteins participating in the NPAS4 regulates expression of target genes pathway from the Reactome Pathways 2024 dataset.

POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Gene Set

From Reactome Pathways 2024

proteins participating in the POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation pathway from the Reactome Pathways 2024 dataset.

POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation Gene Set

From Reactome Pathways 2024

proteins participating in the POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation pathway from the Reactome Pathways 2024 dataset.

RNA polymerase II transcribes snRNA genes Gene Set

From Reactome Pathways 2024

proteins participating in the RNA polymerase II transcribes snRNA genes pathway from the Reactome Pathways 2024 dataset.

RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function pathway from the Reactome Pathways 2024 dataset.

RUNX1 regulates transcription of genes involved in BCR signaling Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX1 regulates transcription of genes involved in BCR signaling pathway from the Reactome Pathways 2024 dataset.

RUNX1 regulates transcription of genes involved in WNT signaling Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX1 regulates transcription of genes involved in WNT signaling pathway from the Reactome Pathways 2024 dataset.

RUNX1 regulates transcription of genes involved in differentiation of HSCs Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX1 regulates transcription of genes involved in differentiation of HSCs pathway from the Reactome Pathways 2024 dataset.

RUNX1 regulates transcription of genes involved in differentiation of keratinocytes Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX1 regulates transcription of genes involved in differentiation of keratinocytes pathway from the Reactome Pathways 2024 dataset.

RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX1 regulates transcription of genes involved in differentiation of myeloid cells pathway from the Reactome Pathways 2024 dataset.

RUNX1 regulates transcription of genes involved in interleukin signaling Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX1 regulates transcription of genes involved in interleukin signaling pathway from the Reactome Pathways 2024 dataset.

RUNX2 regulates genes involved in cell migration Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX2 regulates genes involved in cell migration pathway from the Reactome Pathways 2024 dataset.

RUNX2 regulates genes involved in differentiation of myeloid cells Gene Set

From Reactome Pathways 2024

proteins participating in the RUNX2 regulates genes involved in differentiation of myeloid cells pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M dependent genes involved in invasion Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M dependent genes involved in invasion pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M dependent genes involved in metabolism Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M dependent genes involved in metabolism pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in apoptosis Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in apoptosis pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in cell cycle and proliferation Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in cell cycle and proliferation pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy pathway from the Reactome Pathways 2024 dataset.

Regulation of MITF-M-dependent genes involved in pigmentation Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of MITF-M-dependent genes involved in pigmentation pathway from the Reactome Pathways 2024 dataset.

Repression of WNT target genes Gene Set

From Reactome Pathways 2024

proteins participating in the Repression of WNT target genes pathway from the Reactome Pathways 2024 dataset.

TP53 Regulates Metabolic Genes Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 Regulates Metabolic Genes pathway from the Reactome Pathways 2024 dataset.

TP53 Regulates Transcription of Cell Cycle Genes Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 Regulates Transcription of Cell Cycle Genes pathway from the Reactome Pathways 2024 dataset.

TP53 Regulates Transcription of Cell Death Genes Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 Regulates Transcription of Cell Death Genes pathway from the Reactome Pathways 2024 dataset.

TP53 Regulates Transcription of DNA Repair Genes Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 Regulates Transcription of DNA Repair Genes pathway from the Reactome Pathways 2024 dataset.

TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 Regulates Transcription of Genes Involved in Cytochrome C Release pathway from the Reactome Pathways 2024 dataset.

TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest pathway from the Reactome Pathways 2024 dataset.

TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest pathway from the Reactome Pathways 2024 dataset.

TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain pathway from the Reactome Pathways 2024 dataset.

TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Gene Set

From Reactome Pathways 2024

proteins participating in the TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain pathway from the Reactome Pathways 2024 dataset.

Transcriptional activation of p53 responsive genes Gene Set

From Reactome Pathways 2024

proteins participating in the Transcriptional activation of p53 responsive genes pathway from the Reactome Pathways 2024 dataset.

XBP1(S) activates chaperone genes Gene Set

From Reactome Pathways 2024

proteins participating in the XBP1(S) activates chaperone genes pathway from the Reactome Pathways 2024 dataset.

somatic hypermutation of immunoglobulin genes Gene Set

From GO Biological Process Annotations 2025

genes participating in the somatic hypermutation of immunoglobulin genes biological process from the curated GO Biological Process Annotations 2025 dataset.

somatic recombination of immunoglobulin genes involved in immune response Gene Set

From GO Biological Process Annotations 2025

genes participating in the somatic recombination of immunoglobulin genes involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset.

Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes Gene Set

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Overgrowth syndrome and/or cerebral malformations due to abnormalities in MTOR pathway genes phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

PMC10035130-12885_2023_10749_MOESM5_ESM.xls-genemania-genes-Table_S3_Gene_MANIA_analysis_of_genes_interacting_with_ZBTB4_ZBTB4 Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC10035130-12885_2023_10749_MOESM5_ESM.xls-genemania-genes-Table_S3_Gene_MANIA_analysis_of_genes_interacting_with_ZBTB4_ZBTB4 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-genes-Up-Symbol_ZBTB16 Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-genes-Up-Symbol_ZBTB16 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

PMC4053969-gb-2013-14-7-r81-S3.XLSX-YB1-targeted-genes-gene_YBX1 Gene Set

From Rummagene Transcription Factor Associations 2026

target genes of the PMC4053969-gb-2013-14-7-r81-S3.XLSX-YB1-targeted-genes-gene_YBX1 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.