Name

UFD1L Gene

ubiquitin fusion degradation 1 like (yeast)

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

LOC440489 Gene

ubiquitin fusion degradation 1 like (yeast) pseudogene

ERMARD Gene

ER membrane-associated RNA degradation

The protein encoded by this gene contains 2 transmembrane domains near the C-terminus and is localized in the endoplasmic reticulum. Knockout of this gene in developing rat brain showed that it may be involved in neuronal migration. Mutations in this gene are associated with periventricular nodular heterotopia-6 (PVNH6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

EDEM2 Gene

ER degradation enhancer, mannosidase alpha-like 2

In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]

EDEM3 Gene

ER degradation enhancer, mannosidase alpha-like 3

Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]

EDEM1 Gene

ER degradation enhancer, mannosidase alpha-like 1

Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive regulation of retrograde protein transport, ER to cytosol; protein targeting to ER; and proteolysis involved in protein catabolic process. Located in aggresome and endoplasmic reticulum quality control compartment. [provided by Alliance of Genome Resources, Mar 2025]

UFD1 Gene

ubiquitin recognition factor in ER associated degradation 1

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

PGBDF Gene

plakoglobin binding and degradation factor

CHKA Gene

choline kinase alpha

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

CHKB Gene

choline kinase beta

Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian sources and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus. [provided by RefSeq, Jun 2009]

PCYT1A Gene

phosphate cytidylyltransferase 1, choline, alpha

This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]

PCYT1B Gene

phosphate cytidylyltransferase 1, choline, beta

The protein encoded by this gene belongs to the cytidylyltransferase family. It is involved in the regulation of phosphatidylcholine biosynthesis. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

CHAT Gene

choline O-acetyltransferase

This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010]

CHPT1 Gene

choline phosphotransferase 1

Enables diacylglycerol cholinephosphotransferase activity. Involved in phosphatidylcholine biosynthetic process and platelet activating factor biosynthetic process. Is active in Golgi membrane. [provided by Alliance of Genome Resources, Mar 2025]

CHDH Gene

choline dehydrogenase

The protein encoded by this gene is a choline dehydrogenase that localizes to the mitochondrion. Variations in this gene can affect susceptibility to choline deficiency. A few transcript variants have been found for this gene, but the full-length nature of only one has been characterized to date. [provided by RefSeq, Dec 2010]

SLC44A1 Gene

solute carrier family 44 (choline transporter), member 1

Enables choline transmembrane transporter activity and ethanolamine transmembrane transporter activity. Involved in choline transport; ethanolamine transport; and transmembrane transport. Located in several cellular components, including cytosol; mitochondrial outer membrane; and nucleoplasm. Implicated in high grade glioma. [provided by Alliance of Genome Resources, Mar 2025]

SLC44A2 Gene

solute carrier family 44 (choline transporter), member 2

Enables choline transmembrane transporter activity and ethanolamine transmembrane transporter activity. Involved in choline transport; ethanolamine transport; and transmembrane transport. Located in mitochondrial outer membrane and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

CEPT1 Gene

choline/ethanolamine phosphotransferase 1

This gene codes for a choline/ethanolaminephosphotransferase, which functions in the synthesis of choline- or ethanolamine- containing phospholipids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

SLC5A7 Gene

solute carrier family 5 (sodium/choline cotransporter), member 7

This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

superpathway of choline degradation to L-serine Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of choline degradation to L-serine pathway from the HumanCyc Pathways dataset.

superpathway of methionine degradation Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of methionine degradation pathway from the HumanCyc Pathways dataset.

choline degradation Gene Set

From HumanCyc Pathways

proteins participating in the choline degradation pathway from the HumanCyc Pathways dataset.

superpathway of inositol phosphate compounds Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of inositol phosphate compounds pathway from the HumanCyc Pathways dataset.

superpathway of pyrimidine deoxyribonucleoside salvage Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of pyrimidine deoxyribonucleoside salvage pathway from the HumanCyc Pathways dataset.

superpathway of cholesterol biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of cholesterol biosynthesis pathway from the HumanCyc Pathways dataset.

superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) pathway from the HumanCyc Pathways dataset.

superpathway of purine nucleotide salvage Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of purine nucleotide salvage pathway from the HumanCyc Pathways dataset.

superpathway of pyrimidine ribonucleotides de novo biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of pyrimidine ribonucleotides de novo biosynthesis pathway from the HumanCyc Pathways dataset.

superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism pathway from the HumanCyc Pathways dataset.

superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis pathway from the HumanCyc Pathways dataset.

Cytidine Diphosphate Choline Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Cytidine Diphosphate Choline from the curated CTD Gene-Chemical Interactions dataset.

Choline Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Choline from the curated CTD Gene-Chemical Interactions dataset.

choline deficiency disease Gene Set

From DISEASES Text-mining Gene-Disease Association Evidence Scores

genes co-occuring with the disease choline deficiency disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Choline Gene Set

From DrugBank Drug Targets

interacting proteins for the Choline drug from the curated DrugBank Drug Targets dataset.

Trisalicylate-choline Gene Set

From DrugBank Drug Targets

interacting proteins for the Trisalicylate-choline drug from the curated DrugBank Drug Targets dataset.

choline deficiency; dna damage; folic acid deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease choline deficiency; dna damage; folic acid deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

choline deficiency; fatty liver Gene Set

From GAD Gene-Disease Associations

genes associated with the disease choline deficiency; fatty liver in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

choline deficiency Gene Set

From GAD Gene-Disease Associations

genes associated with the disease choline deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

choline Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term choline in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

choline transport Gene Set

From GO Biological Process Annotations 2015

genes participating in the choline transport biological process from the curated GO Biological Process Annotations 2015 dataset.

cdp-choline pathway Gene Set

From GO Biological Process Annotations 2015

genes participating in the cdp-choline pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of choline o-acetyltransferase activity Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of choline o-acetyltransferase activity biological process from the curated GO Biological Process Annotations 2015 dataset.

choline metabolic process Gene Set

From GO Biological Process Annotations 2015

genes participating in the choline metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

glycine betaine biosynthetic process from choline Gene Set

From GO Biological Process Annotations 2015

genes participating in the glycine betaine biosynthetic process from choline biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of choline o-acetyltransferase activity Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of choline o-acetyltransferase activity biological process from the curated GO Biological Process Annotations 2015 dataset.

choline transmembrane transporter activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the choline transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

choline o-acetyltransferase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the choline o-acetyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

choline:sodium symporter activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the choline:sodium symporter activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

choline kinase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the choline kinase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

choline dehydrogenase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the choline dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

choline binding Gene Set

From GO Molecular Function Annotations 2015

genes performing the choline binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

choline-phosphate cytidylyltransferase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the choline-phosphate cytidylyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Trisalicylate-choline Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Trisalicylate-choline metabolite from the curated HMDB Metabolites of Enzymes dataset.

Choline Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Choline metabolite from the curated HMDB Metabolites of Enzymes dataset.

Choline Deficiency Gene Set

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Choline Deficiency phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Choline transporter-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Choline transporter-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Choline/ethanolamine phosphotransferase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Choline/ethanolamine phosphotransferase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose-methanol-choline oxidoreductase, C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose-methanol-choline oxidoreductase, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose-methanol-choline oxidoreductase, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose-methanol-choline oxidoreductase, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Glucose-methanol-choline oxidoreductase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Glucose-methanol-choline oxidoreductase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Choline Deficiency Gene Set

From DisGeNET Gene-Disease Associations

genes associated with the disease Choline Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Elevated Brain Choline Level By Mrs Gene Set

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Elevated Brain Choline Level By Mrs in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

Reduced Brain Choline Level By Mrs Gene Set

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Reduced Brain Choline Level By Mrs in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

Abnormal Brain Choline Level By Mrs Gene Set

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Abnormal Brain Choline Level By Mrs in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

choline transport Gene Set

From GO Biological Process Annotations 2023

genes participating in the choline transport biological process from the curated GO Biological Process Annotations 2023 dataset.

choline catabolic process Gene Set

From GO Biological Process Annotations 2023

genes participating in the choline catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

CDP-choline pathway Gene Set

From GO Biological Process Annotations 2023

genes participating in the CDP-choline pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

choline metabolic process Gene Set

From GO Biological Process Annotations 2023

genes participating in the choline metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

positive regulation of choline O-acetyltransferase activity Gene Set

From GO Biological Process Annotations 2023

genes participating in the positive regulation of choline O-acetyltransferase activity biological process from the curated GO Biological Process Annotations 2023 dataset.

regulation of choline O-acetyltransferase activity Gene Set

From GO Biological Process Annotations 2023

genes participating in the regulation of choline O-acetyltransferase activity biological process from the curated GO Biological Process Annotations 2023 dataset.

choline transmembrane transporter activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the choline transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

choline O-acetyltransferase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the choline O-acetyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

choline kinase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the choline kinase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

choline-phosphate cytidylyltransferase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the choline-phosphate cytidylyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

choline dehydrogenase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the choline dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

choline:sodium symporter activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the choline:sodium symporter activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

decreased choline O-acetyltransferase activity Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the decreased choline O-acetyltransferase activity phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

decreased brain choline acetyltransferase activity Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the decreased brain choline acetyltransferase activity phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

decreased choline level Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the decreased choline level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

increased brain choline acetyltransferase activity Gene Set

From MGI Mouse Phenotype Associations 2023

gene mutations causing the increased brain choline acetyltransferase activity phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

Choline Gene Set

From MW Enzyme Metabolite Associations

interacting proteins for Choline metabolite from the MW Gene Metabolite Associations dataset.

Choline phosphate Gene Set

From MW Enzyme Metabolite Associations

interacting proteins for Choline phosphate metabolite from the MW Gene Metabolite Associations dataset.

choline Gene Set

From LINCS L1000 CMAP Chemical Perturbation Consensus Signatures

genes differentially expressed following the choline small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

Choline catabolism Gene Set

From Reactome Pathways 2024

proteins participating in the Choline catabolism pathway from the Reactome Pathways 2024 dataset.

choline transport Gene Set

From GO Biological Process Annotations 2025

genes participating in the choline transport biological process from the curated GO Biological Process Annotations 2025 dataset.

choline catabolic process Gene Set

From GO Biological Process Annotations 2025

genes participating in the choline catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

CDP-choline pathway Gene Set

From GO Biological Process Annotations 2025

genes participating in the CDP-choline pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

choline metabolic process Gene Set

From GO Biological Process Annotations 2025

genes participating in the choline metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

choline transmembrane transporter activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the choline transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

choline binding Gene Set

From GO Molecular Function Annotations 2025

genes performing the choline binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

choline O-acetyltransferase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the choline O-acetyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

choline kinase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the choline kinase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

choline-phosphate cytidylyltransferase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the choline-phosphate cytidylyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

choline dehydrogenase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the choline dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

choline:sodium symporter activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the choline:sodium symporter activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Choline deficiency disease Gene Set

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occuring with the disease Choline deficiency disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Choline metabolism in cancer Gene Set

From KEGG Pathways 2026

proteins participating in the Choline metabolism in cancer pathway from the KEGG Pathways 2026 dataset.

DIAZOXIDE CHOLINE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the DIAZOXIDE CHOLINE drug from theDGIdb Drug Targets 2026 dataset.

CHOLINE KINASE ALPHA INHIBITOR TCD-717 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the CHOLINE KINASE ALPHA INHIBITOR TCD-717 drug from theDGIdb Drug Targets 2026 dataset.

CHOLINE CHLORIDE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the CHOLINE CHLORIDE drug from theDGIdb Drug Targets 2026 dataset.

LINZAGOLIX CHOLINE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the LINZAGOLIX CHOLINE drug from theDGIdb Drug Targets 2026 dataset.

ELTROMBOPAG CHOLINE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the ELTROMBOPAG CHOLINE drug from theDGIdb Drug Targets 2026 dataset.

CHOLINE FENOFIBRATE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the CHOLINE FENOFIBRATE drug from theDGIdb Drug Targets 2026 dataset.

er associated degradation (erad) pathway Gene Set

From Biocarta Pathways

proteins participating in the er associated degradation (erad) pathway pathway from the Biocarta Pathways dataset.

degradation of the rar and rxr by the proteasome Gene Set

From Biocarta Pathways

proteins participating in the degradation of the rar and rxr by the proteasome pathway from the Biocarta Pathways dataset.

dna degradation, necrotic Gene Set

From GAD Gene-Disease Associations

genes associated with the disease dna degradation, necrotic in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

degradation Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term degradation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mitochondrion degradation by induced vacuole formation Gene Set

From GO Biological Process Annotations 2015

genes participating in the mitochondrion degradation by induced vacuole formation biological process from the curated GO Biological Process Annotations 2015 dataset.

regulation of mitochondrion degradation Gene Set

From GO Biological Process Annotations 2015

genes participating in the regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

positive regulation of mitochondrion degradation Gene Set

From GO Biological Process Annotations 2015

genes participating in the positive regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

mitochondrion degradation Gene Set

From GO Biological Process Annotations 2015

genes participating in the mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

negative regulation of mitochondrion degradation Gene Set

From GO Biological Process Annotations 2015

genes participating in the negative regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

peroxisome degradation Gene Set

From GO Biological Process Annotations 2015

genes participating in the peroxisome degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

DNA Degradation, Necrotic Gene Set

From HuGE Navigator Gene-Phenotype Associations

genes associated with the DNA Degradation, Necrotic phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

α-tocopherol degradation Gene Set

From HumanCyc Pathways

proteins participating in the α-tocopherol degradation pathway from the HumanCyc Pathways dataset.

sorbitol degradation I Gene Set

From HumanCyc Pathways

proteins participating in the sorbitol degradation I pathway from the HumanCyc Pathways dataset.

methylglyoxal degradation III Gene Set

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation III pathway from the HumanCyc Pathways dataset.

tryptophan degradation Gene Set

From HumanCyc Pathways

proteins participating in the tryptophan degradation pathway from the HumanCyc Pathways dataset.

methylglyoxal degradation VI Gene Set

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation VI pathway from the HumanCyc Pathways dataset.

melatonin degradation II Gene Set

From HumanCyc Pathways

proteins participating in the melatonin degradation II pathway from the HumanCyc Pathways dataset.

alanine biosynthesis/degradation Gene Set

From HumanCyc Pathways

proteins participating in the alanine biosynthesis/degradation pathway from the HumanCyc Pathways dataset.

N-acetylglucosamine degradation I Gene Set

From HumanCyc Pathways

proteins participating in the N-acetylglucosamine degradation I pathway from the HumanCyc Pathways dataset.

glutaryl-CoA degradation Gene Set

From HumanCyc Pathways

proteins participating in the glutaryl-CoA degradation pathway from the HumanCyc Pathways dataset.

asparagine degradation Gene Set

From HumanCyc Pathways

proteins participating in the asparagine degradation pathway from the HumanCyc Pathways dataset.

ethanol degradation IV Gene Set

From HumanCyc Pathways

proteins participating in the ethanol degradation IV pathway from the HumanCyc Pathways dataset.

tyrosine degradation Gene Set

From HumanCyc Pathways

proteins participating in the tyrosine degradation pathway from the HumanCyc Pathways dataset.

glutamate biosynthesis/degradation Gene Set

From HumanCyc Pathways

proteins participating in the glutamate biosynthesis/degradation pathway from the HumanCyc Pathways dataset.

superoxide radicals degradation Gene Set

From HumanCyc Pathways

proteins participating in the superoxide radicals degradation pathway from the HumanCyc Pathways dataset.

phenylethylamine degradation I Gene Set

From HumanCyc Pathways

proteins participating in the phenylethylamine degradation I pathway from the HumanCyc Pathways dataset.

putrescine degradation III Gene Set

From HumanCyc Pathways

proteins participating in the putrescine degradation III pathway from the HumanCyc Pathways dataset.

S-methyl-5-thio-α-D-ribose 1-phosphate degradation Gene Set

From HumanCyc Pathways

proteins participating in the S-methyl-5-thio-α-D-ribose 1-phosphate degradation pathway from the HumanCyc Pathways dataset.

3-phosphoinositide degradation Gene Set

From HumanCyc Pathways

proteins participating in the 3-phosphoinositide degradation pathway from the HumanCyc Pathways dataset.

methionine degradation Gene Set

From HumanCyc Pathways

proteins participating in the methionine degradation pathway from the HumanCyc Pathways dataset.

trehalose degradation Gene Set

From HumanCyc Pathways

proteins participating in the trehalose degradation pathway from the HumanCyc Pathways dataset.

thyroid hormone metabolism II (via conjugation and/or degradation) Gene Set

From HumanCyc Pathways

proteins participating in the thyroid hormone metabolism II (via conjugation and/or degradation) pathway from the HumanCyc Pathways dataset.

S-methyl-5'-thioadenosine degradation Gene Set

From HumanCyc Pathways

proteins participating in the S-methyl-5'-thioadenosine degradation pathway from the HumanCyc Pathways dataset.

tryptophan degradation X (mammalian, via tryptamine) Gene Set

From HumanCyc Pathways

proteins participating in the tryptophan degradation X (mammalian, via tryptamine) pathway from the HumanCyc Pathways dataset.

lactose degradation III Gene Set

From HumanCyc Pathways

proteins participating in the lactose degradation III pathway from the HumanCyc Pathways dataset.

phenylalanine degradation/tyrosine biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the phenylalanine degradation/tyrosine biosynthesis pathway from the HumanCyc Pathways dataset.

L-cysteine degradation II Gene Set

From HumanCyc Pathways

proteins participating in the L-cysteine degradation II pathway from the HumanCyc Pathways dataset.

tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde Gene Set

From HumanCyc Pathways

proteins participating in the tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde pathway from the HumanCyc Pathways dataset.

ethanol degradation II Gene Set

From HumanCyc Pathways

proteins participating in the ethanol degradation II pathway from the HumanCyc Pathways dataset.

uracil degradation Gene Set

From HumanCyc Pathways

proteins participating in the uracil degradation pathway from the HumanCyc Pathways dataset.

L-kynurenine degradation Gene Set

From HumanCyc Pathways

proteins participating in the L-kynurenine degradation pathway from the HumanCyc Pathways dataset.

threonine degradation Gene Set

From HumanCyc Pathways

proteins participating in the threonine degradation pathway from the HumanCyc Pathways dataset.

D-myo-inositol (1,4,5)-trisphosphate degradation Gene Set

From HumanCyc Pathways

proteins participating in the D-myo-inositol (1,4,5)-trisphosphate degradation pathway from the HumanCyc Pathways dataset.

cysteine biosynthesis/homocysteine degradation (trans-sulfuration) Gene Set

From HumanCyc Pathways

proteins participating in the cysteine biosynthesis/homocysteine degradation (trans-sulfuration) pathway from the HumanCyc Pathways dataset.

serotonin degradation Gene Set

From HumanCyc Pathways

proteins participating in the serotonin degradation pathway from the HumanCyc Pathways dataset.

methylglyoxal degradation I Gene Set

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation I pathway from the HumanCyc Pathways dataset.

dermatan sulfate degradation (metazoa) Gene Set

From HumanCyc Pathways

proteins participating in the dermatan sulfate degradation (metazoa) pathway from the HumanCyc Pathways dataset.

guanosine nucleotides degradation Gene Set

From HumanCyc Pathways

proteins participating in the guanosine nucleotides degradation pathway from the HumanCyc Pathways dataset.

pyrimidine deoxyribonucleosides degradation Gene Set

From HumanCyc Pathways

proteins participating in the pyrimidine deoxyribonucleosides degradation pathway from the HumanCyc Pathways dataset.

lysine degradation II (pipecolate pathway) Gene Set

From HumanCyc Pathways

proteins participating in the lysine degradation II (pipecolate pathway) pathway from the HumanCyc Pathways dataset.

L-dopa degradation Gene Set

From HumanCyc Pathways

proteins participating in the L-dopa degradation pathway from the HumanCyc Pathways dataset.

histamine degradation Gene Set

From HumanCyc Pathways

proteins participating in the histamine degradation pathway from the HumanCyc Pathways dataset.

2'-deoxy-α-D-ribose 1-phosphate degradation Gene Set

From HumanCyc Pathways

proteins participating in the 2'-deoxy-α-D-ribose 1-phosphate degradation pathway from the HumanCyc Pathways dataset.

pyrimidine ribonucleosides degradation Gene Set

From HumanCyc Pathways

proteins participating in the pyrimidine ribonucleosides degradation pathway from the HumanCyc Pathways dataset.

D-mannose degradation Gene Set

From HumanCyc Pathways

proteins participating in the D-mannose degradation pathway from the HumanCyc Pathways dataset.

purine nucleotides degradation Gene Set

From HumanCyc Pathways

proteins participating in the purine nucleotides degradation pathway from the HumanCyc Pathways dataset.

noradrenaline and adrenaline degradation Gene Set

From HumanCyc Pathways

proteins participating in the noradrenaline and adrenaline degradation pathway from the HumanCyc Pathways dataset.

2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA Gene Set

From HumanCyc Pathways

proteins participating in the 2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA pathway from the HumanCyc Pathways dataset.

4-aminobutyrate degradation Gene Set

From HumanCyc Pathways

proteins participating in the 4-aminobutyrate degradation pathway from the HumanCyc Pathways dataset.

anandamide degradation Gene Set

From HumanCyc Pathways

proteins participating in the anandamide degradation pathway from the HumanCyc Pathways dataset.

glycine betaine degradation Gene Set

From HumanCyc Pathways

proteins participating in the glycine betaine degradation pathway from the HumanCyc Pathways dataset.

spermine and spermidine degradation I Gene Set

From HumanCyc Pathways

proteins participating in the spermine and spermidine degradation I pathway from the HumanCyc Pathways dataset.

glycerol degradation Gene Set

From HumanCyc Pathways

proteins participating in the glycerol degradation pathway from the HumanCyc Pathways dataset.

phytol degradation Gene Set

From HumanCyc Pathways

proteins participating in the phytol degradation pathway from the HumanCyc Pathways dataset.

dopamine degradation Gene Set

From HumanCyc Pathways

proteins participating in the dopamine degradation pathway from the HumanCyc Pathways dataset.

L-cysteine degradation I Gene Set

From HumanCyc Pathways

proteins participating in the L-cysteine degradation I pathway from the HumanCyc Pathways dataset.

histidine degradation Gene Set

From HumanCyc Pathways

proteins participating in the histidine degradation pathway from the HumanCyc Pathways dataset.

β-alanine degradation Gene Set

From HumanCyc Pathways

proteins participating in the β-alanine degradation pathway from the HumanCyc Pathways dataset.

sucrose degradation Gene Set

From HumanCyc Pathways

proteins participating in the sucrose degradation pathway from the HumanCyc Pathways dataset.

D-galactose degradation V (Leloir pathway) Gene Set

From HumanCyc Pathways

proteins participating in the D-galactose degradation V (Leloir pathway) pathway from the HumanCyc Pathways dataset.

urate biosynthesis/inosine 5'-phosphate degradation Gene Set

From HumanCyc Pathways

proteins participating in the urate biosynthesis/inosine 5'-phosphate degradation pathway from the HumanCyc Pathways dataset.

glutamine degradation/glutamate biosynthesis Gene Set

From HumanCyc Pathways

proteins participating in the glutamine degradation/glutamate biosynthesis pathway from the HumanCyc Pathways dataset.

purine deoxyribonucleosides degradation Gene Set

From HumanCyc Pathways

proteins participating in the purine deoxyribonucleosides degradation pathway from the HumanCyc Pathways dataset.

lysine degradation I (saccharopine pathway) Gene Set

From HumanCyc Pathways

proteins participating in the lysine degradation I (saccharopine pathway) pathway from the HumanCyc Pathways dataset.

oxidative ethanol degradation III Gene Set

From HumanCyc Pathways

proteins participating in the oxidative ethanol degradation III pathway from the HumanCyc Pathways dataset.

4-hydroxyproline degradation Gene Set

From HumanCyc Pathways

proteins participating in the 4-hydroxyproline degradation pathway from the HumanCyc Pathways dataset.

triacylglycerol degradation Gene Set

From HumanCyc Pathways

proteins participating in the triacylglycerol degradation pathway from the HumanCyc Pathways dataset.

purine ribonucleosides degradation to ribose-1-phosphate Gene Set

From HumanCyc Pathways

proteins participating in the purine ribonucleosides degradation to ribose-1-phosphate pathway from the HumanCyc Pathways dataset.

heme degradation Gene Set

From HumanCyc Pathways

proteins participating in the heme degradation pathway from the HumanCyc Pathways dataset.

propionyl-CoA degradation Gene Set

From HumanCyc Pathways

proteins participating in the propionyl-CoA degradation pathway from the HumanCyc Pathways dataset.

proline degradation Gene Set

From HumanCyc Pathways

proteins participating in the proline degradation pathway from the HumanCyc Pathways dataset.

2-oxobutanoate degradation Gene Set

From HumanCyc Pathways

proteins participating in the 2-oxobutanoate degradation pathway from the HumanCyc Pathways dataset.

chondroitin sulfate degradation (metazoa) Gene Set

From HumanCyc Pathways

proteins participating in the chondroitin sulfate degradation (metazoa) pathway from the HumanCyc Pathways dataset.

D-glucuronate degradation Gene Set

From HumanCyc Pathways

proteins participating in the D-glucuronate degradation pathway from the HumanCyc Pathways dataset.

N-acetylglucosamine degradation II Gene Set

From HumanCyc Pathways

proteins participating in the N-acetylglucosamine degradation II pathway from the HumanCyc Pathways dataset.

adenosine nucleotides degradation Gene Set

From HumanCyc Pathways

proteins participating in the adenosine nucleotides degradation pathway from the HumanCyc Pathways dataset.

thymine degradation Gene Set

From HumanCyc Pathways

proteins participating in the thymine degradation pathway from the HumanCyc Pathways dataset.

Phenylacetic acid degradation-related domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phenylacetic acid degradation-related domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Ubiquitin fusion degradation protein UFD1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ubiquitin fusion degradation protein UFD1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Vacuolar import/degradation protein Vid24 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Vacuolar import/degradation protein Vid24 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

atrazine degradation Gene Set

From KEGG Pathways

proteins participating in the atrazine degradation pathway from the KEGG Pathways dataset.

3 chloroacrylic acid degradation Gene Set

From KEGG Pathways

proteins participating in the 3 chloroacrylic acid degradation pathway from the KEGG Pathways dataset.

1 and 2 methylnaphthalene degradation Gene Set

From KEGG Pathways

proteins participating in the 1 and 2 methylnaphthalene degradation pathway from the KEGG Pathways dataset.

naphthalene and anthracene degradation Gene Set

From KEGG Pathways

proteins participating in the naphthalene and anthracene degradation pathway from the KEGG Pathways dataset.

caprolactam degradation Gene Set

From KEGG Pathways

proteins participating in the caprolactam degradation pathway from the KEGG Pathways dataset.

ethylbenzene degradation Gene Set

From KEGG Pathways

proteins participating in the ethylbenzene degradation pathway from the KEGG Pathways dataset.

gamma hexachlorocyclohexane degradation Gene Set

From KEGG Pathways

proteins participating in the gamma hexachlorocyclohexane degradation pathway from the KEGG Pathways dataset.

limonene and pinene degradation Gene Set

From KEGG Pathways

proteins participating in the limonene and pinene degradation pathway from the KEGG Pathways dataset.

bisphenol a degradation Gene Set

From KEGG Pathways

proteins participating in the bisphenol a degradation pathway from the KEGG Pathways dataset.

1,4 dichlorobenzene degradation Gene Set

From KEGG Pathways

proteins participating in the 1,4 dichlorobenzene degradation pathway from the KEGG Pathways dataset.

benzoate degradation via coa ligation Gene Set

From KEGG Pathways

proteins participating in the benzoate degradation via coa ligation pathway from the KEGG Pathways dataset.

tetrachloroethene degradation Gene Set

From KEGG Pathways

proteins participating in the tetrachloroethene degradation pathway from the KEGG Pathways dataset.

n glycan degradation Gene Set

From KEGG Pathways

proteins participating in the n glycan degradation pathway from the KEGG Pathways dataset.

synthesis and degradation of ketone bodies Gene Set

From KEGG Pathways

proteins participating in the synthesis and degradation of ketone bodies pathway from the KEGG Pathways dataset.

styrene degradation Gene Set

From KEGG Pathways

proteins participating in the styrene degradation pathway from the KEGG Pathways dataset.

valine leucine and isoleucine degradation Gene Set

From KEGG Pathways

proteins participating in the valine leucine and isoleucine degradation pathway from the KEGG Pathways dataset.

lysine degradation Gene Set

From KEGG Pathways

proteins participating in the lysine degradation pathway from the KEGG Pathways dataset.

glycosaminoglycan degradation Gene Set

From KEGG Pathways

proteins participating in the glycosaminoglycan degradation pathway from the KEGG Pathways dataset.

glycan structures degradation Gene Set

From KEGG Pathways

proteins participating in the glycan structures degradation pathway from the KEGG Pathways dataset.

Ornithine degradation Gene Set

From PANTHER Pathways

proteins participating in the Ornithine degradation pathway from the PANTHER Pathways dataset.

Ascorbate degradation Gene Set

From PANTHER Pathways

proteins participating in the Ascorbate degradation pathway from the PANTHER Pathways dataset.

Phenylethylamine degradation Gene Set

From PANTHER Pathways

proteins participating in the Phenylethylamine degradation pathway from the PANTHER Pathways dataset.

Allantoin degradation Gene Set

From PANTHER Pathways

proteins participating in the Allantoin degradation pathway from the PANTHER Pathways dataset.

Aminobutyrate degradation Gene Set

From PANTHER Pathways

proteins participating in the Aminobutyrate degradation pathway from the PANTHER Pathways dataset.

degradation Gene Set

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term degradation in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Degradation of beta catenin Gene Set

From PID Pathways

proteins participating in the Degradation of beta catenin pathway from the PID Pathways dataset.

SCF-beta-TrCP mediated degradation of Emi1 Gene Set

From Reactome Pathways 2014

proteins participating in the SCF-beta-TrCP mediated degradation of Emi1 pathway from the Reactome Pathways dataset.

Degradation of GABA Gene Set

From Reactome Pathways 2014

proteins participating in the Degradation of GABA pathway from the Reactome Pathways dataset.

HS-GAG degradation Gene Set

From Reactome Pathways 2014

proteins participating in the HS-GAG degradation pathway from the Reactome Pathways dataset.

Gap junction degradation Gene Set

From Reactome Pathways 2014

proteins participating in the Gap junction degradation pathway from the Reactome Pathways dataset.

Ubiquitin-dependent degradation of Cyclin D1 Gene Set

From Reactome Pathways 2014

proteins participating in the Ubiquitin-dependent degradation of Cyclin D1 pathway from the Reactome Pathways dataset.

Hyaluronan uptake and degradation Gene Set

From Reactome Pathways 2014

proteins participating in the Hyaluronan uptake and degradation pathway from the Reactome Pathways dataset.

Biosynthesis of A2E, implicated in retinal degradation Gene Set

From Reactome Pathways 2014

proteins participating in the Biosynthesis of A2E, implicated in retinal degradation pathway from the Reactome Pathways dataset.

APC/C:Cdc20 mediated degradation of mitotic proteins Gene Set

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways dataset.

APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint Gene Set

From Reactome Pathways 2014

proteins participating in the APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint pathway from the Reactome Pathways dataset.

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Gene Set

From Reactome Pathways 2014

proteins participating in the Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways dataset.

Enzymatic degradation of Dopamine by monoamine oxidase Gene Set

From Reactome Pathways 2014

proteins participating in the Enzymatic degradation of Dopamine by monoamine oxidase pathway from the Reactome Pathways dataset.

Enzymatic degradation of dopamine by COMT Gene Set

From Reactome Pathways 2014

proteins participating in the Enzymatic degradation of dopamine by COMT pathway from the Reactome Pathways dataset.

APC-Cdc20 mediated degradation of Nek2A Gene Set

From Reactome Pathways 2014

proteins participating in the APC-Cdc20 mediated degradation of Nek2A pathway from the Reactome Pathways dataset.

degradation of DVL Gene Set

From Reactome Pathways 2014

proteins participating in the degradation of DVL pathway from the Reactome Pathways dataset.

Keratan sulfate degradation Gene Set

From Reactome Pathways 2014

proteins participating in the Keratan sulfate degradation pathway from the Reactome Pathways dataset.

degradation of AXIN Gene Set

From Reactome Pathways 2014

proteins participating in the degradation of AXIN pathway from the Reactome Pathways dataset.

Degradation of GLI2 by the proteasome Gene Set

From Reactome Pathways 2014

proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways dataset.

CS/DS degradation Gene Set

From Reactome Pathways 2014

proteins participating in the CS/DS degradation pathway from the Reactome Pathways dataset.

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Gene Set

From Reactome Pathways 2014

proteins participating in the APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway from the Reactome Pathways dataset.

Regulation of activated PAK-2p34 by proteasome mediated degradation Gene Set

From Reactome Pathways 2014

proteins participating in the Regulation of activated PAK-2p34 by proteasome mediated degradation pathway from the Reactome Pathways dataset.

Degradation of cysteine and homocysteine Gene Set

From Reactome Pathways 2014

proteins participating in the Degradation of cysteine and homocysteine pathway from the Reactome Pathways dataset.

Collagen degradation Gene Set

From Reactome Pathways 2014

proteins participating in the Collagen degradation pathway from the Reactome Pathways dataset.

GABA synthesis, release, reuptake and degradation Gene Set

From Reactome Pathways 2014

proteins participating in the GABA synthesis, release, reuptake and degradation pathway from the Reactome Pathways dataset.

APC/C:Cdc20 mediated degradation of Securin Gene Set

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of Securin pathway from the Reactome Pathways dataset.

APC/C:Cdc20 mediated degradation of Cyclin B Gene Set

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of Cyclin B pathway from the Reactome Pathways dataset.

SCF(Skp2)-mediated degradation of p27/p21 Gene Set

From Reactome Pathways 2014

proteins participating in the SCF(Skp2)-mediated degradation of p27/p21 pathway from the Reactome Pathways dataset.

Ubiquitin-dependent degradation of Cyclin D Gene Set

From Reactome Pathways 2014

proteins participating in the Ubiquitin-dependent degradation of Cyclin D pathway from the Reactome Pathways dataset.

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Gene Set

From Reactome Pathways 2014

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways dataset.

Vif-mediated degradation of APOBEC3G Gene Set

From Reactome Pathways 2014

proteins participating in the Vif-mediated degradation of APOBEC3G pathway from the Reactome Pathways dataset.

APC/C-mediated degradation of cell cycle proteins Gene Set

From Reactome Pathways 2014

proteins participating in the APC/C-mediated degradation of cell cycle proteins pathway from the Reactome Pathways dataset.

Degradation of the extracellular matrix Gene Set

From Reactome Pathways 2014

proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways dataset.

Vpu mediated degradation of CD4 Gene Set

From Reactome Pathways 2014

proteins participating in the Vpu mediated degradation of CD4 pathway from the Reactome Pathways dataset.

Cdc20:Phospho-APC/C mediated degradation of Cyclin A Gene Set

From Reactome Pathways 2014

proteins participating in the Cdc20:Phospho-APC/C mediated degradation of Cyclin A pathway from the Reactome Pathways dataset.

Antigen processing: Ubiquitination & Proteasome degradation Gene Set

From Reactome Pathways 2014

proteins participating in the Antigen processing: Ubiquitination & Proteasome degradation pathway from the Reactome Pathways dataset.

Heme degradation Gene Set

From Reactome Pathways 2014

proteins participating in the Heme degradation pathway from the Reactome Pathways dataset.

Degradation of GLI1 by the proteasome Gene Set

From Reactome Pathways 2014

proteins participating in the Degradation of GLI1 by the proteasome pathway from the Reactome Pathways dataset.

Degradation of beta-catenin by the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the Degradation of beta-catenin by the destruction complex pathway from the Reactome Pathways dataset.

Synthesis and Degradation of Ketone Bodies(Mus musculus) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Synthesis and Degradation of Ketone Bodies(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

Proteasome Degradation(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Proteasome Degradation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

Proteasome Degradation(Mus musculus) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Proteasome Degradation(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

Synthesis and Degradation of Ketone Bodies(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the Synthesis and Degradation of Ketone Bodies(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

PCSK9-mediated LDLR degradation(Homo sapiens) Gene Set

From WikiPathways Pathways 2014

proteins participating in the PCSK9-mediated LDLR degradation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

target-directed miRNA degradation Gene Set

From GO Biological Process Annotations 2023

genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2023 dataset.

Proteasome degradation Gene Set

From WikiPathways Pathways 2024

proteins participating in the Proteasome degradation pathway from the WikiPathways Pathways 2024 dataset.

PCSK9 mediated LDL receptor degradation Gene Set

From WikiPathways Pathways 2024

proteins participating in the PCSK9 mediated LDL receptor degradation pathway from the WikiPathways Pathways 2024 dataset.

Degradation pathway of sphingolipids including diseases Gene Set

From WikiPathways Pathways 2024

proteins participating in the Degradation pathway of sphingolipids including diseases pathway from the WikiPathways Pathways 2024 dataset.

Gamma glutamyl cycle for the biosynthesis and degradation of glutathione including diseases Gene Set

From WikiPathways Pathways 2024

proteins participating in the Gamma glutamyl cycle for the biosynthesis and degradation of glutathione including diseases pathway from the WikiPathways Pathways 2024 dataset.

Glycosaminoglycan degradation Gene Set

From WikiPathways Pathways 2024

proteins participating in the Glycosaminoglycan degradation pathway from the WikiPathways Pathways 2024 dataset.

Glycogen synthesis and degradation Gene Set

From WikiPathways Pathways 2024

proteins participating in the Glycogen synthesis and degradation pathway from the WikiPathways Pathways 2024 dataset.

APC-Cdc20 mediated degradation of Nek2A Gene Set

From Reactome Pathways 2024

proteins participating in the APC-Cdc20 mediated degradation of Nek2A pathway from the Reactome Pathways 2024 dataset.

APC/C-mediated degradation of cell cycle proteins Gene Set

From Reactome Pathways 2024

proteins participating in the APC/C-mediated degradation of cell cycle proteins pathway from the Reactome Pathways 2024 dataset.

APC/C:Cdc20 mediated degradation of Cyclin B Gene Set

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of Cyclin B pathway from the Reactome Pathways 2024 dataset.

APC/C:Cdc20 mediated degradation of Securin Gene Set

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of Securin pathway from the Reactome Pathways 2024 dataset.

APC/C:Cdc20 mediated degradation of mitotic proteins Gene Set

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways 2024 dataset.

APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Gene Set

From Reactome Pathways 2024

proteins participating in the APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway from the Reactome Pathways 2024 dataset.

APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint Gene Set

From Reactome Pathways 2024

proteins participating in the APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint pathway from the Reactome Pathways 2024 dataset.

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Gene Set

From Reactome Pathways 2024

proteins participating in the Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways 2024 dataset.

Antigen processing: Ubiquitination & Proteasome degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Antigen processing: Ubiquitination & Proteasome degradation pathway from the Reactome Pathways 2024 dataset.

Biosynthesis of A2E, implicated in retinal degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Biosynthesis of A2E, implicated in retinal degradation pathway from the Reactome Pathways 2024 dataset.

CS/DS degradation Gene Set

From Reactome Pathways 2024

proteins participating in the CS/DS degradation pathway from the Reactome Pathways 2024 dataset.

Cdc20:Phospho-APC/C mediated degradation of Cyclin A Gene Set

From Reactome Pathways 2024

proteins participating in the Cdc20:Phospho-APC/C mediated degradation of Cyclin A pathway from the Reactome Pathways 2024 dataset.

Collagen degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Collagen degradation pathway from the Reactome Pathways 2024 dataset.

Degradation of AXIN Gene Set

From Reactome Pathways 2024

proteins participating in the Degradation of AXIN pathway from the Reactome Pathways 2024 dataset.

Degradation of DVL Gene Set

From Reactome Pathways 2024

proteins participating in the Degradation of DVL pathway from the Reactome Pathways 2024 dataset.

Degradation of GABA Gene Set

From Reactome Pathways 2024

proteins participating in the Degradation of GABA pathway from the Reactome Pathways 2024 dataset.

Degradation of GLI1 by the proteasome Gene Set

From Reactome Pathways 2024

proteins participating in the Degradation of GLI1 by the proteasome pathway from the Reactome Pathways 2024 dataset.

Degradation of GLI2 by the proteasome Gene Set

From Reactome Pathways 2024

proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways 2024 dataset.

Degradation of beta-catenin by the destruction complex Gene Set

From Reactome Pathways 2024

proteins participating in the Degradation of beta-catenin by the destruction complex pathway from the Reactome Pathways 2024 dataset.

Degradation of cysteine and homocysteine Gene Set

From Reactome Pathways 2024

proteins participating in the Degradation of cysteine and homocysteine pathway from the Reactome Pathways 2024 dataset.

Degradation of the extracellular matrix Gene Set

From Reactome Pathways 2024

proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways 2024 dataset.

Enzymatic degradation of Dopamine by monoamine oxidase Gene Set

From Reactome Pathways 2024

proteins participating in the Enzymatic degradation of Dopamine by monoamine oxidase pathway from the Reactome Pathways 2024 dataset.

Enzymatic degradation of dopamine by COMT Gene Set

From Reactome Pathways 2024

proteins participating in the Enzymatic degradation of dopamine by COMT pathway from the Reactome Pathways 2024 dataset.

GABA synthesis, release, reuptake and degradation Gene Set

From Reactome Pathways 2024

proteins participating in the GABA synthesis, release, reuptake and degradation pathway from the Reactome Pathways 2024 dataset.

GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 Gene Set

From Reactome Pathways 2024

proteins participating in the GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 pathway from the Reactome Pathways 2024 dataset.

Gap junction degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Gap junction degradation pathway from the Reactome Pathways 2024 dataset.

Glycine degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Glycine degradation pathway from the Reactome Pathways 2024 dataset.

Glyoxylate metabolism and glycine degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Glyoxylate metabolism and glycine degradation pathway from the Reactome Pathways 2024 dataset.

HS-GAG degradation Gene Set

From Reactome Pathways 2024

proteins participating in the HS-GAG degradation pathway from the Reactome Pathways 2024 dataset.

Heme degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Heme degradation pathway from the Reactome Pathways 2024 dataset.

Hyaluronan uptake and degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Hyaluronan uptake and degradation pathway from the Reactome Pathways 2024 dataset.

Keratan sulfate degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Keratan sulfate degradation pathway from the Reactome Pathways 2024 dataset.

M-decay: degradation of maternal mRNAs by maternally stored factors Gene Set

From Reactome Pathways 2024

proteins participating in the M-decay: degradation of maternal mRNAs by maternally stored factors pathway from the Reactome Pathways 2024 dataset.

Mitochondrial RNA degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Mitochondrial RNA degradation pathway from the Reactome Pathways 2024 dataset.

Mitochondrial protein degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Mitochondrial protein degradation pathway from the Reactome Pathways 2024 dataset.

Regulation of TP53 Degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of TP53 Degradation pathway from the Reactome Pathways 2024 dataset.

Regulation of TP53 Expression and Degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of TP53 Expression and Degradation pathway from the Reactome Pathways 2024 dataset.

Regulation of activated PAK-2p34 by proteasome mediated degradation Gene Set

From Reactome Pathways 2024

proteins participating in the Regulation of activated PAK-2p34 by proteasome mediated degradation pathway from the Reactome Pathways 2024 dataset.

SCF(Skp2)-mediated degradation of p27/p21 Gene Set

From Reactome Pathways 2024

proteins participating in the SCF(Skp2)-mediated degradation of p27/p21 pathway from the Reactome Pathways 2024 dataset.

SCF-beta-TrCP mediated degradation of Emi1 Gene Set

From Reactome Pathways 2024

proteins participating in the SCF-beta-TrCP mediated degradation of Emi1 pathway from the Reactome Pathways 2024 dataset.

Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Gene Set

From Reactome Pathways 2024

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways 2024 dataset.

Ubiquitin-dependent degradation of Cyclin D Gene Set

From Reactome Pathways 2024

proteins participating in the Ubiquitin-dependent degradation of Cyclin D pathway from the Reactome Pathways 2024 dataset.

VLDLR internalisation and degradation Gene Set

From Reactome Pathways 2024

proteins participating in the VLDLR internalisation and degradation pathway from the Reactome Pathways 2024 dataset.

Vif-mediated degradation of APOBEC3G Gene Set

From Reactome Pathways 2024

proteins participating in the Vif-mediated degradation of APOBEC3G pathway from the Reactome Pathways 2024 dataset.

Vpu mediated degradation of CD4 Gene Set

From Reactome Pathways 2024

proteins participating in the Vpu mediated degradation of CD4 pathway from the Reactome Pathways 2024 dataset.

Z-decay: degradation of maternal mRNAs by zygotically expressed factors Gene Set

From Reactome Pathways 2024

proteins participating in the Z-decay: degradation of maternal mRNAs by zygotically expressed factors pathway from the Reactome Pathways 2024 dataset.

target-directed miRNA degradation Gene Set

From GO Biological Process Annotations 2025

genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2025 dataset.

Ethanolamine degradation polyhedral organelle Gene Set

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Ethanolamine degradation polyhedral organelle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Fatty acid degradation Gene Set

From KEGG Pathways 2026

proteins participating in the Fatty acid degradation pathway from the KEGG Pathways 2026 dataset.

Valine, leucine and isoleucine degradation Gene Set

From KEGG Pathways 2026

proteins participating in the Valine, leucine and isoleucine degradation pathway from the KEGG Pathways 2026 dataset.

Lysine degradation Gene Set

From KEGG Pathways 2026

proteins participating in the Lysine degradation pathway from the KEGG Pathways 2026 dataset.

Glycosaminoglycan degradation Gene Set

From KEGG Pathways 2026

proteins participating in the Glycosaminoglycan degradation pathway from the KEGG Pathways 2026 dataset.

Other glycan degradation Gene Set

From KEGG Pathways 2026

proteins participating in the Other glycan degradation pathway from the KEGG Pathways 2026 dataset.

RNA degradation Gene Set

From KEGG Pathways 2026

proteins participating in the RNA degradation pathway from the KEGG Pathways 2026 dataset.