Harmonizome 3.0

ubiquitin fusion degradation 1 like (yeast)

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

ubiquitin fusion degradation 1 like (yeast) pseudogene

ER membrane-associated RNA degradation

The protein encoded by this gene contains 2 transmembrane domains near the C-terminus and is localized in the endoplasmic reticulum. Knockout of this gene in developing rat brain showed that it may be involved in neuronal migration. Mutations in this gene are associated with periventricular nodular heterotopia-6 (PVNH6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

ER degradation enhancer, mannosidase alpha-like 2

In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]

ER degradation enhancer, mannosidase alpha-like 3

Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]

ER degradation enhancer, mannosidase alpha-like 1

Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive regulation of retrograde protein transport, ER to cytosol; protein targeting to ER; and proteolysis involved in protein catabolic process. Located in aggresome and endoplasmic reticulum quality control compartment. [provided by Alliance of Genome Resources, Mar 2025]

ubiquitin recognition factor in ER associated degradation 1

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

plakoglobin binding and degradation factor

PWP2 periodic tryptophan protein homolog (yeast)

Enables RNA binding activity. Involved in ribosomal small subunit biogenesis. Part of small-subunit processome. [provided by Alliance of Genome Resources, Mar 2025]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways. [provided by RefSeq, Jul 2008]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 8

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 9

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 2

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 3

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 1

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 6

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 5

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide pseudogene

tryptophan rich basic protein

This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4. [provided by RefSeq, Apr 2017]

tryptophan hydroxylase 1

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]

tryptophan hydroxylase 2

This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]

tryptophan 2,3-dioxygenase

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide pseudogene

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 7

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta pseudogene 4

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide pseudogene

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon pseudogene 5

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon pseudogene 7

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon pseudogene 1

tryptophan rich basic protein pseudogene 1

periodic tryptophan protein 2 homolog

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta pseudogene 2

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta pseudogene 1

transfer RNA tryptophan (anticodon CCA)

This record serves to anchor the annotations of this class of tRNAs at multiple locations on the human genome. The placements are predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).

From HumanCyc Pathways

proteins participating in the tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the tryptophan degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the tryptophan degradation X (mammalian, via tryptamine) pathway from the HumanCyc Pathways dataset.

From ClinVar Gene-Phenotype Associations

genes associated with the Succinate-semialdehyde dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical succinic semialdehyde from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Disease Associations

genes/proteins associated with the disease succinic semialdehyde dehydrogenase deficiency from the curated CTD Gene-Disease Associations dataset.

From DISEASES Curated Gene-Disease Association Evidence Scores

genes involed in the disease succinic semialdehyde dehydrogenase deficiency from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores

genes co-occuring with the disease succinic semialdehyde dehydrogenase deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term semialdehyde in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Molecular Function Annotations 2015

genes performing the succinate-semialdehyde dehydrogenase binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the methylmalonate-semialdehyde dehydrogenase (acylating) activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the succinate-semialdehyde dehydrogenase (nad+) activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the glutamate-5-semialdehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the aminocarboxymuconate-semialdehyde decarboxylase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the malonate-semialdehyde dehydrogenase (acetylating) activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the l-aminoadipate-semialdehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the succinate-semialdehyde dehydrogenase [nad(p)+] activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the Tartronate semialdehyde metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the L-Glutamic gamma-semialdehyde metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the Malonic semialdehyde metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the Adipate semialdehyde metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the 2-Aminomuconic acid semialdehyde metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the L-4-Hydroxyglutamate semialdehyde metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the (S)-Methylmalonic acid semialdehyde metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the Succinic acid semialdehyde metabolite from the curated HMDB Metabolites of Enzymes dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methylmalonate-semialdehyde dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Succinate semialdehyde dehydrogenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From OMIM Gene-Disease Associations

genes associated with the methylmalonate semialdehyde dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the succinic semialdehyde dehydrogenase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Alpha-Aminoadipic Semialdehyde Deficiency Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Succinic Semialdehyde Dehydrogenase Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Methylmalonate Semialdehyde Dehydrogenase Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From GO Molecular Function Annotations 2023

genes performing the succinate-semialdehyde dehydrogenase (NAD+) activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the glutamate-5-semialdehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the succinate-semialdehyde dehydrogenase binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the methylmalonate-semialdehyde dehydrogenase (acylating) activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the malonate-semialdehyde dehydrogenase (acetylating) activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the aminocarboxymuconate-semialdehyde decarboxylase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the succinate-semialdehyde dehydrogenase [NAD(P)+] activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From MW Enzyme Metabolite Associations

interacting proteins for Succinic acid semialdehyde metabolite from the MW Gene Metabolite Associations dataset.

From MW Enzyme Metabolite Associations

interacting proteins for (S)-Methylmalonate semialdehyde metabolite from the MW Gene Metabolite Associations dataset.

From MW Enzyme Metabolite Associations

interacting proteins for L-2-Aminoadipate 6-semialdehyde metabolite from the MW Gene Metabolite Associations dataset.

From MW Enzyme Metabolite Associations

interacting proteins for L-Glutamic-gamma-semialdehyde metabolite from the MW Gene Metabolite Associations dataset.

From GO Molecular Function Annotations 2025

genes performing the succinate-semialdehyde dehydrogenase (NAD+) activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the glutamate-5-semialdehyde dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the succinate-semialdehyde dehydrogenase binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the aminocarboxymuconate-semialdehyde decarboxylase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the succinate-semialdehyde dehydrogenase [NAD(P)+] activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From DISEASES Curated Gene-Disease Association Evidence Scores 2025

genes involed in the disease Succinic semialdehyde dehydrogenase deficiency from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occuring with the disease Succinic semialdehyde dehydrogenase deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Succinate-semialdehyde dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Methylmalonate semialdehyde dehydrogenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide from the curated CTD Gene-Chemical Interactions dataset.

From DrugBank Drug Targets

interacting proteins for the N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the Imino-Tryptophan drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the L-Tryptophan drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the D-Tryptophan drug from the curated DrugBank Drug Targets dataset.

From GAD Gene-Disease Associations

genes associated with the disease behavioral traits; tryptophan depletion sensitivity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease tryptophan catabolism in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tryptophan in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the tryptophan catabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the tryptophan catabolic process to acetyl-coa biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-tryptophan modification biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the 'de novo' nad biosynthetic process from tryptophan biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the tryptophan catabolic process to kynurenine biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the protein c-linked glycosylation via 2'-alpha-mannosyl-l-tryptophan biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the tryptophan metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the tryptophan transport biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the protein c-linked glycosylation via tryptophan biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the tryptophan-trna ligase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the tryptophan 5-monooxygenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the tryptophan 2,3-dioxygenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the D-tryptophan ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the 5-hydroxy-L-tryptophan ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the α-methyl-D L-tryptophan ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the L-tryptophan ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From GWASdb SNP-Phenotype Associations

genes associated with the abnormality of tryptophan metabolism phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the L-Tryptophan metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the D-Tryptophan metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the 5-Hydroxy-L-tryptophan metabolite from the curated HMDB Metabolites of Enzymes dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tryptophan 2,3-dioxygenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Periodic tryptophan protein 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tryptophan 5-monooxygenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tryptophan-tRNA ligase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tryptophan synthase beta subunit-like PLP-dependent enzyme protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tryptophan-tRNA ligase, bacterial-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From KEGG Pathways

proteins participating in the phenylalanine tyrosine and tryptophan biosynthesis pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the tryptophan metabolism pathway from the KEGG Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Tryptophan catabolism pathway from the Reactome Pathways dataset.

From WikiPathways Pathways 2014

proteins participating in the Tryptophan metabolism(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Tryptophan metabolism(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the NAD Biosynthesis II (from tryptophan)(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Tryptophan Measurement in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

From GO Biological Process Annotations 2023

genes participating in the tryptophan catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tryptophan transport biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tryptophan catabolic process to kynurenine biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the L-tryptophan transmembrane transport biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tryptophan metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of 'de novo' NAD biosynthetic process from tryptophan biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tryptophan catabolic process to indole-3-acetate biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the 'de novo' NAD biosynthetic process from tryptophan biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tryptophan catabolic process to acetyl-CoA biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of tryptophan metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the protein C-linked glycosylation via tryptophan biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the 5-hydroxy-L-tryptophan decarboxylase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the tryptophan-tRNA ligase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the tryptophan 2,3-dioxygenase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the L-tryptophan transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the tryptophan 5-monooxygenase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From MW Enzyme Metabolite Associations

interacting proteins for Tryptophan metabolite from the MW Gene Metabolite Associations dataset.

From MW Enzyme Metabolite Associations

interacting proteins for 5-Hydroxy-tryptophan metabolite from the MW Gene Metabolite Associations dataset.

From WikiPathways Pathways 2024

proteins participating in the NAD biosynthesis II from tryptophan pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Tryptophan catabolism leading to NAD production pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Tryptophan metabolism pathway from the WikiPathways Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Tryptophan catabolism pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-tryptophan catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the tryptophan transport biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-tryptophan catabolic process to kynurenine biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-tryptophan transmembrane transport biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-tryptophan metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of 'de novo' NAD biosynthetic process from L-tryptophan biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-tryptophan catabolic process to indole-3-acetate biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the 'de novo' NAD biosynthetic process from L-tryptophan biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-tryptophan catabolic process to acetyl-CoA biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of L-tryptophan metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the protein C-linked glycosylation via tryptophan biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the 5-hydroxy-L-tryptophan decarboxylase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the tryptophan-tRNA ligase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the tryptophan 2,3-dioxygenase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the L-tryptophan transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the tryptophan 5-monooxygenase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Tryptophan 5-monooxygenase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the CSF tryptophan concentration in tuberculous meningitis phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Plasma kynurenine to tryptophan ratio in major depressive disorder phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From KEGG Pathways 2026

proteins participating in the Tryptophan metabolism pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the Phenylalanine, tyrosine and tryptophan biosynthesis pathway from the KEGG Pathways 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the LISINOPRIL-TRYPTOPHAN drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the DL-TRYPTOPHAN drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the TRYPTOPHAN drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the D-TRYPTOPHAN drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the 1-METHYL-L-TRYPTOPHAN drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the Α-METHYL-D,L-TRYPTOPHAN drug from theDGIdb Drug Targets 2026 dataset.

From Biocarta Pathways

proteins participating in the er associated degradation (erad) pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the degradation of the rar and rxr by the proteasome pathway from the Biocarta Pathways dataset.

From GAD Gene-Disease Associations

genes associated with the disease dna degradation, necrotic in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term degradation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mitochondrion degradation by induced vacuole formation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peroxisome degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From HuGE Navigator Gene-Phenotype Associations

genes associated with the DNA Degradation, Necrotic phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

From HumanCyc Pathways

proteins participating in the α-tocopherol degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the sorbitol degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation III pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation VI pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the melatonin degradation II pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-serine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the alanine biosynthesis/degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the N-acetylglucosamine degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glutaryl-CoA degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the asparagine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the ethanol degradation IV pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the tyrosine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glutamate biosynthesis/degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the superoxide radicals degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the phenylethylamine degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the putrescine degradation III pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the S-methyl-5-thio-α-D-ribose 1-phosphate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 3-phosphoinositide degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the methionine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the trehalose degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the thyroid hormone metabolism II (via conjugation and/or degradation) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the S-methyl-5'-thioadenosine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the lactose degradation III pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the phenylalanine degradation/tyrosine biosynthesis pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-cysteine degradation II pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the ethanol degradation II pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the uracil degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-kynurenine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the threonine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the D-myo-inositol (1,4,5)-trisphosphate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the cysteine biosynthesis/homocysteine degradation (trans-sulfuration) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the superpathway of choline degradation to L-serine pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the serotonin degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the dermatan sulfate degradation (metazoa) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the guanosine nucleotides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the pyrimidine deoxyribonucleosides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the lysine degradation II (pipecolate pathway) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-dopa degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the histamine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 2'-deoxy-α-D-ribose 1-phosphate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the pyrimidine ribonucleosides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the D-mannose degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the purine nucleotides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the noradrenaline and adrenaline degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the superpathway of methionine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 4-aminobutyrate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the anandamide degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glycine betaine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the spermine and spermidine degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glycerol degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the phytol degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the dopamine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-cysteine degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the histidine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the β-alanine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the sucrose degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the D-galactose degradation V (Leloir pathway) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the urate biosynthesis/inosine 5'-phosphate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glutamine degradation/glutamate biosynthesis pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the purine deoxyribonucleosides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the lysine degradation I (saccharopine pathway) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the oxidative ethanol degradation III pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 4-hydroxyproline degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the triacylglycerol degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the purine ribonucleosides degradation to ribose-1-phosphate pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the heme degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the propionyl-CoA degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the proline degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 2-oxobutanoate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the chondroitin sulfate degradation (metazoa) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the D-glucuronate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the N-acetylglucosamine degradation II pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the adenosine nucleotides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the thymine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the choline degradation pathway from the HumanCyc Pathways dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phenylacetic acid degradation-related domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ubiquitin fusion degradation protein UFD1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Vacuolar import/degradation protein Vid24 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From KEGG Pathways

proteins participating in the atrazine degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the 3 chloroacrylic acid degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the 1 and 2 methylnaphthalene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the naphthalene and anthracene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the caprolactam degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the ethylbenzene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the gamma hexachlorocyclohexane degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the limonene and pinene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the bisphenol a degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the 1,4 dichlorobenzene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the benzoate degradation via coa ligation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the tetrachloroethene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the n glycan degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the synthesis and degradation of ketone bodies pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the styrene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the valine leucine and isoleucine degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the lysine degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the glycosaminoglycan degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the glycan structures degradation pathway from the KEGG Pathways dataset.

From PANTHER Pathways

proteins participating in the Ornithine degradation pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Ascorbate degradation pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Phenylethylamine degradation pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Allantoin degradation pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Aminobutyrate degradation pathway from the PANTHER Pathways dataset.

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term degradation in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

From PID Pathways

proteins participating in the Degradation of beta catenin pathway from the PID Pathways dataset.

From Reactome Pathways 2014

proteins participating in the SCF-beta-TrCP mediated degradation of Emi1 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of GABA pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the HS-GAG degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Gap junction degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Ubiquitin-dependent degradation of Cyclin D1 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Hyaluronan uptake and degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Biosynthesis of A2E, implicated in retinal degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Enzymatic degradation of Dopamine by monoamine oxidase pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Enzymatic degradation of dopamine by COMT pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC-Cdc20 mediated degradation of Nek2A pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the degradation of DVL pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Keratan sulfate degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the degradation of AXIN pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the CS/DS degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Regulation of activated PAK-2p34 by proteasome mediated degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of cysteine and homocysteine pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Collagen degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the GABA synthesis, release, reuptake and degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of Securin pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of Cyclin B pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the SCF(Skp2)-mediated degradation of p27/p21 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Ubiquitin-dependent degradation of Cyclin D pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Vif-mediated degradation of APOBEC3G pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C-mediated degradation of cell cycle proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Vpu mediated degradation of CD4 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Cdc20:Phospho-APC/C mediated degradation of Cyclin A pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Antigen processing: Ubiquitination & Proteasome degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Heme degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of GLI1 by the proteasome pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of beta-catenin by the destruction complex pathway from the Reactome Pathways dataset.

From WikiPathways Pathways 2014

proteins participating in the Synthesis and Degradation of Ketone Bodies(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Proteasome Degradation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Proteasome Degradation(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Synthesis and Degradation of Ketone Bodies(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the PCSK9-mediated LDLR degradation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From GO Biological Process Annotations 2023

genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2023 dataset.

From WikiPathways Pathways 2024

proteins participating in the Proteasome degradation pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the PCSK9 mediated LDL receptor degradation pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Degradation pathway of sphingolipids including diseases pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Gamma glutamyl cycle for the biosynthesis and degradation of glutathione including diseases pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Glycosaminoglycan degradation pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Glycogen synthesis and degradation pathway from the WikiPathways Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC-Cdc20 mediated degradation of Nek2A pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C-mediated degradation of cell cycle proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of Cyclin B pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of Securin pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Antigen processing: Ubiquitination & Proteasome degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Biosynthesis of A2E, implicated in retinal degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the CS/DS degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Cdc20:Phospho-APC/C mediated degradation of Cyclin A pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Collagen degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of AXIN pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of DVL pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of GABA pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of GLI1 by the proteasome pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of beta-catenin by the destruction complex pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of cysteine and homocysteine pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Enzymatic degradation of Dopamine by monoamine oxidase pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Enzymatic degradation of dopamine by COMT pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the GABA synthesis, release, reuptake and degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Gap junction degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Glycine degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Glyoxylate metabolism and glycine degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the HS-GAG degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Heme degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Hyaluronan uptake and degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Keratan sulfate degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the M-decay: degradation of maternal mRNAs by maternally stored factors pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Mitochondrial RNA degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Mitochondrial protein degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Regulation of TP53 Degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Regulation of TP53 Expression and Degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Regulation of activated PAK-2p34 by proteasome mediated degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SCF(Skp2)-mediated degradation of p27/p21 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SCF-beta-TrCP mediated degradation of Emi1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Ubiquitin-dependent degradation of Cyclin D pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the VLDLR internalisation and degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Vif-mediated degradation of APOBEC3G pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Vpu mediated degradation of CD4 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Z-decay: degradation of maternal mRNAs by zygotically expressed factors pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Ethanolamine degradation polyhedral organelle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From KEGG Pathways 2026

proteins participating in the Fatty acid degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the Valine, leucine and isoleucine degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the Lysine degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the Glycosaminoglycan degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the Other glycan degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the RNA degradation pathway from the KEGG Pathways 2026 dataset.