| Name |
|---|
FAS-AS1 GeneFAS antisense RNA 1 Predicted to be involved in regulation of gene expression. [provided by Alliance of Genome Resources, Mar 2025] |
FAS GeneFas cell surface death receptor The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011] |
PTPN13 Geneprotein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008] |
FBF1 GeneFas (TNFRSF6) binding factor 1 Involved in apical junction assembly and establishment of epithelial cell polarity. Acts upstream of or within cilium assembly. Located in apical junction complex and cytoskeleton. Part of ciliary transition fiber. [provided by Alliance of Genome Resources, Mar 2025] |
FAIM2 GeneFas apoptotic inhibitory molecule 2 Predicted to enable calcium channel activity. Involved in regulation of neuron apoptotic process. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway via death domain receptors. Located in Golgi membrane and membrane raft. [provided by Alliance of Genome Resources, Mar 2025] |
FADD GeneFas (TNFRSF6)-associated via death domain The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008] |
FAF2P1 GeneFas associated factor family member 2 pseudogene 1 |
FASTK GeneFas-activated serine/threonine kinase The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008] |
FAF1 GeneFas (TNFRSF6) associated factor 1 Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008] |
FAF2 GeneFas associated factor family member 2 The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008] |
FASLG GeneFas ligand (TNF superfamily, member 6) This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] |
FAIM GeneFas apoptotic inhibitory molecule The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] |
FAS LIGAND Gene Setinteracting proteins for the FAS LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
Fas ligand pathway and stress induction of heat shock proteins Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Fas ligand pathway and stress induction of heat shock proteins pathway from the WikiPathways Pathways 2024 dataset. |
RECOMBINANT FAS LIGAND Gene Setinteracting proteins for the RECOMBINANT FAS LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
fas signaling pathway (cd95) Gene SetFrom Biocarta Pathways proteins participating in the fas signaling pathway (cd95) pathway from the Biocarta Pathways dataset. |
hiv-1 nef: negative effector of fas and tnf Gene SetFrom Biocarta Pathways proteins participating in the hiv-1 nef: negative effector of fas and tnf pathway from the Biocarta Pathways dataset. |
FAS-FADD-CASP10 complex Gene Setproteins in the FAS-FADD-CASP10 complex protein complex from the CORUM Protein Complexes dataset. |
Death induced signaling complex DISC (FAS, FADD, CASP8, CFLAR), membrane-associated, CD95L induced Gene Setproteins in the Death induced signaling complex DISC (FAS, FADD, CASP8, CFLAR), membrane-associated, CD95L induced protein complex from the CORUM Protein Complexes dataset. |
FAS-FADD-CASP8-CASP10 complex Gene Setproteins in the FAS-FADD-CASP8-CASP10 complex protein complex from the CORUM Protein Complexes dataset. |
FAS-FADD-CASP8 complex Gene Setproteins in the FAS-FADD-CASP8 complex protein complex from the CORUM Protein Complexes dataset. |
fas Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term fas in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
regulation of fas signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of fas signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
fas signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the fas signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of fas signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of fas signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
fas-activated serine/threonine kinase activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the fas-activated serine/threonine kinase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
Fas activated serine/threonine kinase FAST Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Fas activated serine/threonine kinase FAST protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Fas apoptotic inhibitory molecule Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Fas apoptotic inhibitory molecule protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Thioesterase type II, NRPS/PKS/S-FAS Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Thioesterase type II, NRPS/PKS/S-FAS protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Fas receptor Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Fas receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
FAS Gene SetFrom MSigDB Cancer Gene Co-expression Modules co-expressed genes for FAS from the MSigDB Cancer Gene Co-expression Modules dataset. |
FAS signaling pathway Gene SetFrom PANTHER Pathways proteins participating in the FAS signaling pathway pathway from the PANTHER Pathways dataset. |
FAS Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for FAS from the Pathway Commons Protein-Protein Interactions dataset. |
fas Gene SetFrom Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term fas in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset. |
FAS (CD95) signaling pathway Gene SetFrom PID Pathways proteins participating in the FAS (CD95) signaling pathway pathway from the PID Pathways dataset. |
HIV-1 Nef: Negative effector of Fas and TNF-alpha Gene SetFrom PID Pathways proteins participating in the HIV-1 Nef: Negative effector of Fas and TNF-alpha pathway from the PID Pathways dataset. |
FAS pathway and Stress induction of HSP regulation(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the FAS pathway and Stress induction of HSP regulation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
FAS pathway and Stress induction of HSP regulation(Mus musculus) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the FAS pathway and Stress induction of HSP regulation(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset. |
regulation of Fas signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of Fas signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
Fas signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the Fas signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of Fas signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of Fas signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
FAS Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the FAS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
regulation of Fas signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of Fas signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
Fas signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the Fas signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of Fas signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of Fas signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
cbl mediated ligand-induced downregulation of egf receptors pathway Gene SetFrom Biocarta Pathways proteins participating in the cbl mediated ligand-induced downregulation of egf receptors pathway pathway from the Biocarta Pathways dataset. |
9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex Gene Setproteins in the 9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex protein complex from the CORUM Protein Complexes dataset. |
6S-nuclear aryl hydrocarbon (Ah) receptor ligand-activated complex Gene Setproteins in the 6S-nuclear aryl hydrocarbon (Ah) receptor ligand-activated complex protein complex from the CORUM Protein Complexes dataset. |
CBP-RARA-RXRA-DNA complex, ligand stimulated Gene Setproteins in the CBP-RARA-RXRA-DNA complex, ligand stimulated protein complex from the CORUM Protein Complexes dataset. |
CD40 Ligand Gene SetFrom dbGAP Gene-Trait Associations genes associated with the trait CD40 Ligand in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset. |
cd40 ligand deficiency Gene SetFrom DISEASES Curated Gene-Disease Association Evidence Scores genes involed in the disease cd40 ligand deficiency from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset. |
cd40 ligand deficiency Gene SetFrom DISEASES Text-mining Gene-Disease Association Evidence Scores genes co-occuring with the disease cd40 ligand deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset. |
cd40 ligand Gene SetFrom GAD Gene-Disease Associations genes associated with the disease cd40 ligand in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
ligand Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ligand in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
chemokine (c-c motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the chemokine (c-c motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
chemokine (c-c motif) ligand 2 secretion Gene SetFrom GO Biological Process Annotations 2015 genes participating in the chemokine (c-c motif) ligand 2 secretion biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of chemokine (c-x-c motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of chemokine (c-x-c motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of chemokine (c-c motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of chemokine (c-c motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
chemokine (c-c motif) ligand 21 signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the chemokine (c-c motif) ligand 21 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of chemokine (c-x-c motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of chemokine (c-x-c motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
sequestering of extracellular ligand from receptor Gene SetFrom GO Biological Process Annotations 2015 genes participating in the sequestering of extracellular ligand from receptor biological process from the curated GO Biological Process Annotations 2015 dataset. |
extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2015 genes participating in the extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of chemokine (c-x-c motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of chemokine (c-x-c motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of chemokine (c-x-c motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of chemokine (c-x-c motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
chemokine (c-c motif) ligand 19 signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the chemokine (c-c motif) ligand 19 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of ligand-dependent nuclear receptor transcription coactivator activity Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of ligand-dependent nuclear receptor transcription coactivator activity biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of chemokine (c-x-c motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of chemokine (c-x-c motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of chemokine (c-c motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of chemokine (c-c motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of ligand-dependent nuclear receptor transcription coactivator activity Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of ligand-dependent nuclear receptor transcription coactivator activity biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the positive regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
signal transduction in absence of ligand Gene SetFrom GO Biological Process Annotations 2015 genes participating in the signal transduction in absence of ligand biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of chemokine (c-c motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of chemokine (c-c motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
chemokine (c-c motif) ligand 11 production Gene SetFrom GO Biological Process Annotations 2015 genes participating in the chemokine (c-c motif) ligand 11 production biological process from the curated GO Biological Process Annotations 2015 dataset. |
patched ligand maturation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the patched ligand maturation biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of signal transduction in absence of ligand Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of signal transduction in absence of ligand biological process from the curated GO Biological Process Annotations 2015 dataset. |
inhibitory extracellular ligand-gated ion channel activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the inhibitory extracellular ligand-gated ion channel activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
ligand-activated sequence-specific dna binding rna polymerase ii transcription factor activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the ligand-activated sequence-specific dna binding rna polymerase ii transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
ligand-activated rna polymerase ii transcription factor binding transcription factor activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the ligand-activated rna polymerase ii transcription factor binding transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
chemokine (c-c motif) ligand 19 binding Gene SetFrom GO Molecular Function Annotations 2015 genes performing the chemokine (c-c motif) ligand 19 binding molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
extracellular ligand-gated ion channel activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the extracellular ligand-gated ion channel activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
intracellular ligand-gated ion channel activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the intracellular ligand-gated ion channel activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
ligand-dependent nuclear receptor transcription coactivator activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the ligand-dependent nuclear receptor transcription coactivator activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
chemokine (c-c motif) ligand 5 binding Gene SetFrom GO Molecular Function Annotations 2015 genes performing the chemokine (c-c motif) ligand 5 binding molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
ligand-gated ion channel activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the ligand-gated ion channel activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
ligand-gated channel activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the ligand-gated channel activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
ligand-dependent nuclear receptor binding Gene SetFrom GO Molecular Function Annotations 2015 genes performing the ligand-dependent nuclear receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
excitatory extracellular ligand-gated ion channel activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the excitatory extracellular ligand-gated ion channel activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
direct ligand regulated sequence-specific dna binding transcription factor activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the direct ligand regulated sequence-specific dna binding transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
chemokine (c-c motif) ligand 7 binding Gene SetFrom GO Molecular Function Annotations 2015 genes performing the chemokine (c-c motif) ligand 7 binding molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
chemokine (c-c motif) ligand 21 binding Gene SetFrom GO Molecular Function Annotations 2015 genes performing the chemokine (c-c motif) ligand 21 binding molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
intracellular ligand-gated calcium channel activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the intracellular ligand-gated calcium channel activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
ligand-gated sodium channel activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the ligand-gated sodium channel activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
Peroxidases heam-ligand binding site Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Peroxidases heam-ligand binding site protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Tumor necrosis factor ligand superfamily member 15 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Tumor necrosis factor ligand superfamily member 15 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Immunoglobulin C2-set-like, ligand-binding Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Immunoglobulin C2-set-like, ligand-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
NO signalling/Golgi transport ligand-binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the NO signalling/Golgi transport ligand-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Tumour necrosis factor ligand 10/11 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Tumour necrosis factor ligand 10/11 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
CD40 ligand Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the CD40 ligand protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Ligand-dependent nuclear receptor-interacting factor 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Ligand-dependent nuclear receptor-interacting factor 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Tumour necrosis factor family protein, CD30 ligand type Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Tumour necrosis factor family protein, CD30 ligand type protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
C chemokine ligand 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the C chemokine ligand 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Neurotransmitter-gated ion-channel ligand-binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Neurotransmitter-gated ion-channel ligand-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Extracellular ligand-binding receptor Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Extracellular ligand-binding receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Nuclear hormone receptor, ligand-binding, core Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Nuclear hormone receptor, ligand-binding, core protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
NKG2D ligand, RAE-1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the NKG2D ligand, RAE-1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Growth hormone/erythropoietin receptor, ligand binding Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Growth hormone/erythropoietin receptor, ligand binding protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Calcium signal-modulating cyclophilin ligand Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Calcium signal-modulating cyclophilin ligand protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Ephrin receptor ligand binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Ephrin receptor ligand binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Nuclear hormone receptor, ligand-binding Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Nuclear hormone receptor, ligand-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Notch ligand, N-terminal Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Notch ligand, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Epidermal growth factor receptor ligand Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Epidermal growth factor receptor ligand protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Flt3 ligand Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Flt3 ligand protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Tumor necrosis factor ligand superfamily member 6 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Tumor necrosis factor ligand superfamily member 6 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
P-selectin glycoprotein ligand 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the P-selectin glycoprotein ligand 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Soluble ligand binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Soluble ligand binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
neuroactive ligand receptor interaction Gene SetFrom KEGG Pathways proteins participating in the neuroactive ligand receptor interaction pathway from the KEGG Pathways dataset. |
hypercholesterolemia, due to ligand-defective apo b Gene SetFrom OMIM Gene-Disease Associations genes associated with the hypercholesterolemia, due to ligand-defective apo b phenotype from the curated OMIM Gene-Disease Associations dataset. |
ligand-dependent Gene SetFrom Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term ligand-dependent in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset. |
Alpha6 beta4 integrin-ligand interactions Gene SetFrom PID Pathways proteins participating in the Alpha6 beta4 integrin-ligand interactions pathway from the PID Pathways dataset. |
Klotho-mediated ligand binding Gene Setproteins participating in the Klotho-mediated ligand binding pathway from the Reactome Pathways dataset. |
WNT ligand biogenesis and trafficking Gene Setproteins participating in the WNT ligand biogenesis and trafficking pathway from the Reactome Pathways dataset. |
betaKlotho-mediated ligand binding Gene Setproteins participating in the betaKlotho-mediated ligand binding pathway from the Reactome Pathways dataset. |
Eicosanoid ligand-binding receptors Gene Setproteins participating in the Eicosanoid ligand-binding receptors pathway from the Reactome Pathways dataset. |
Signaling by Ligand-Responsive EGFR Variants in Cancer Gene Setproteins participating in the Signaling by Ligand-Responsive EGFR Variants in Cancer pathway from the Reactome Pathways dataset. |
Calcitonin-like ligand receptors Gene Setproteins participating in the Calcitonin-like ligand receptors pathway from the Reactome Pathways dataset. |
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 Gene Setproteins participating in the WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 pathway from the Reactome Pathways dataset. |
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Gene Setproteins participating in the Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants pathway from the Reactome Pathways dataset. |
Amine ligand-binding receptors Gene Setproteins participating in the Amine ligand-binding receptors pathway from the Reactome Pathways dataset. |
Peptide ligand-binding receptors Gene Setproteins participating in the Peptide ligand-binding receptors pathway from the Reactome Pathways dataset. |
FGFR3c ligand binding and activation Gene Setproteins participating in the FGFR3c ligand binding and activation pathway from the Reactome Pathways dataset. |
Ligand-receptor interactions Gene Setproteins participating in the Ligand-receptor interactions pathway from the Reactome Pathways dataset. |
FGFR1c ligand binding and activation Gene Setproteins participating in the FGFR1c ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR1c and Klotho ligand binding and activation Gene Setproteins participating in the FGFR1c and Klotho ligand binding and activation pathway from the Reactome Pathways dataset. |
GPCR ligand binding Gene Setproteins participating in the GPCR ligand binding pathway from the Reactome Pathways dataset. |
Prostanoid ligand receptors Gene Setproteins participating in the Prostanoid ligand receptors pathway from the Reactome Pathways dataset. |
FGFR3 ligand binding and activation Gene Setproteins participating in the FGFR3 ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR3b ligand binding and activation Gene Setproteins participating in the FGFR3b ligand binding and activation pathway from the Reactome Pathways dataset. |
Ligand-gated ion channel transport Gene Setproteins participating in the Ligand-gated ion channel transport pathway from the Reactome Pathways dataset. |
Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor Gene Setproteins participating in the Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor pathway from the Reactome Pathways dataset. |
FGFR2 ligand binding and activation Gene Setproteins participating in the FGFR2 ligand binding and activation pathway from the Reactome Pathways dataset. |
VEGF ligand-receptor interactions Gene Setproteins participating in the VEGF ligand-receptor interactions pathway from the Reactome Pathways dataset. |
Hormone ligand-binding receptors Gene Setproteins participating in the Hormone ligand-binding receptors pathway from the Reactome Pathways dataset. |
FGFR2c ligand binding and activation Gene Setproteins participating in the FGFR2c ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR1b ligand binding and activation Gene Setproteins participating in the FGFR1b ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR2b ligand binding and activation Gene Setproteins participating in the FGFR2b ligand binding and activation pathway from the Reactome Pathways dataset. |
Hh ligand biogenesis disease Gene Setproteins participating in the Hh ligand biogenesis disease pathway from the Reactome Pathways dataset. |
FGFR4 ligand binding and activation Gene Setproteins participating in the FGFR4 ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR ligand binding and activation Gene Setproteins participating in the FGFR ligand binding and activation pathway from the Reactome Pathways dataset. |
negative regulation of TCF-dependent signaling by WNT ligand antagonists Gene Setproteins participating in the negative regulation of TCF-dependent signaling by WNT ligand antagonists pathway from the Reactome Pathways dataset. |
Hedgehog ligand biogenesis Gene Setproteins participating in the Hedgehog ligand biogenesis pathway from the Reactome Pathways dataset. |
FGFR1 ligand binding and activation Gene Setproteins participating in the FGFR1 ligand binding and activation pathway from the Reactome Pathways dataset. |
Glucagon-type ligand receptors Gene Setproteins participating in the Glucagon-type ligand receptors pathway from the Reactome Pathways dataset. |
Processing-defective Hh variants abrogate ligand secretion Gene Setproteins participating in the Processing-defective Hh variants abrogate ligand secretion pathway from the Reactome Pathways dataset. |
Small Ligand GPCRs(Mus musculus) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Small Ligand GPCRs(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset. |
Small Ligand GPCRs(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Small Ligand GPCRs(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
Hypercholesterolemia, Familial, Due To Ligand-Defective Apolipoprotein B Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Hypercholesterolemia, Familial, Due To Ligand-Defective Apolipoprotein B in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Cd40 Ligand Deficiency Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Cd40 Ligand Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Chemokine (C-C Motif) Ligand 21 Measurement Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype Chemokine (C-C Motif) Ligand 21 Measurement in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
Chemokine (C-C Motif) Ligand 19 Measurement Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype Chemokine (C-C Motif) Ligand 19 Measurement in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
Chemokine (C-X-C Motif) Ligand 6 Measurement Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype Chemokine (C-X-C Motif) Ligand 6 Measurement in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
positive regulation of chemokine (C-X-C motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of chemokine (C-X-C motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of chemokine (C-C motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of chemokine (C-C motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
chemokine (C-C motif) ligand 21 signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the chemokine (C-C motif) ligand 21 signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of chemokine (C-X-C motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of chemokine (C-X-C motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
chemokine (C-X-C motif) ligand 12 signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the chemokine (C-X-C motif) ligand 12 signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2023 genes participating in the extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2023 dataset. |
sequestering of extracellular ligand from receptor Gene SetFrom GO Biological Process Annotations 2023 genes participating in the sequestering of extracellular ligand from receptor biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of chemokine (C-C motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of chemokine (C-C motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
signaling receptor ligand precursor processing Gene SetFrom GO Biological Process Annotations 2023 genes participating in the signaling receptor ligand precursor processing biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of chemokine (C-X-C motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of chemokine (C-X-C motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of chemokine (C-X-C motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of chemokine (C-X-C motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
epidermal growth factor receptor ligand maturation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the epidermal growth factor receptor ligand maturation biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation of chemokine (C-C motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the positive regulation of chemokine (C-C motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of chemokine (C-X-C motif) ligand 9 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of chemokine (C-X-C motif) ligand 9 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of chemokine (C-C motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of chemokine (C-C motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of signal transduction in absence of ligand Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of signal transduction in absence of ligand biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of chemokine (C-X-C motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of chemokine (C-X-C motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of chemokine (C-C motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of chemokine (C-C motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of chemokine (C-X-C motif) ligand 9 production Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of chemokine (C-X-C motif) ligand 9 production biological process from the curated GO Biological Process Annotations 2023 dataset. |
transforming growth factor beta ligand-receptor complex Gene SetFrom GO Cellular Component Annotations 2023 proteins localized to the transforming growth factor beta ligand-receptor complex cellular component from the curated GO Cellular Component Annotations 2023 dataset. |
receptor ligand activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the receptor ligand activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential Gene SetFrom GO Molecular Function Annotations 2023 genes performing the ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
ligand-gated calcium channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the ligand-gated calcium channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
chemokine (C-C motif) ligand 7 binding Gene SetFrom GO Molecular Function Annotations 2023 genes performing the chemokine (C-C motif) ligand 7 binding molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
chemokine (C-C motif) ligand 5 binding Gene SetFrom GO Molecular Function Annotations 2023 genes performing the chemokine (C-C motif) ligand 5 binding molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
chemokine (C-C motif) ligand 19 binding Gene SetFrom GO Molecular Function Annotations 2023 genes performing the chemokine (C-C motif) ligand 19 binding molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
chemokine (C-C motif) ligand 21 binding Gene SetFrom GO Molecular Function Annotations 2023 genes performing the chemokine (C-C motif) ligand 21 binding molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
ligand-gated sodium channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the ligand-gated sodium channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
extracellular ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the extracellular ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
excitatory extracellular ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the excitatory extracellular ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
inhibitory extracellular ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the inhibitory extracellular ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
ligand-gated monoatomic cation channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the ligand-gated monoatomic cation channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
ligand-gated monoatomic anion channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the ligand-gated monoatomic anion channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
intracellular ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the intracellular ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
ligand-gated channel activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the ligand-gated channel activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
decreased tumor necrosis factor (ligand) superfamily member 11 level Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased tumor necrosis factor (ligand) superfamily member 11 level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
increased tumor necrosis factor (ligand) superfamily member 11 level Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the increased tumor necrosis factor (ligand) superfamily member 11 level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
ligand-gated ion channel activity involved in regulation of presynaptic membrane potential Gene SetFrom SynGO Synaptic Gene Annotations genes associated with the synaptic term ligand-gated ion channel activity involved in regulation of presynaptic membrane potential from the SynGO Synaptic Gene Annotations dataset. |
Small ligand GPCRs Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Small ligand GPCRs pathway from the WikiPathways Pathways 2024 dataset. |
Amine ligand-binding receptors Gene Setproteins participating in the Amine ligand-binding receptors pathway from the Reactome Pathways 2024 dataset. |
Calcitonin-like ligand receptors Gene Setproteins participating in the Calcitonin-like ligand receptors pathway from the Reactome Pathways 2024 dataset. |
Caspase activation via Death Receptors in the presence of ligand Gene Setproteins participating in the Caspase activation via Death Receptors in the presence of ligand pathway from the Reactome Pathways 2024 dataset. |
Caspase activation via Dependence Receptors in the absence of ligand Gene Setproteins participating in the Caspase activation via Dependence Receptors in the absence of ligand pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants Gene Setproteins participating in the Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants pathway from the Reactome Pathways 2024 dataset. |
Defective regulation of TLR7 by endogenous ligand Gene Setproteins participating in the Defective regulation of TLR7 by endogenous ligand pathway from the Reactome Pathways 2024 dataset. |
Eicosanoid ligand-binding receptors Gene Setproteins participating in the Eicosanoid ligand-binding receptors pathway from the Reactome Pathways 2024 dataset. |
FGFR1 ligand binding and activation Gene Setproteins participating in the FGFR1 ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR1b ligand binding and activation Gene Setproteins participating in the FGFR1b ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR1c and Klotho ligand binding and activation Gene Setproteins participating in the FGFR1c and Klotho ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR1c ligand binding and activation Gene Setproteins participating in the FGFR1c ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR2 ligand binding and activation Gene Setproteins participating in the FGFR2 ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR2b ligand binding and activation Gene Setproteins participating in the FGFR2b ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR2c ligand binding and activation Gene Setproteins participating in the FGFR2c ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR3 ligand binding and activation Gene Setproteins participating in the FGFR3 ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR3b ligand binding and activation Gene Setproteins participating in the FGFR3b ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR3c ligand binding and activation Gene Setproteins participating in the FGFR3c ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR4 ligand binding and activation Gene Setproteins participating in the FGFR4 ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
GPCR ligand binding Gene Setproteins participating in the GPCR ligand binding pathway from the Reactome Pathways 2024 dataset. |
Glucagon-type ligand receptors Gene Setproteins participating in the Glucagon-type ligand receptors pathway from the Reactome Pathways 2024 dataset. |
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Gene Setproteins participating in the HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand pathway from the Reactome Pathways 2024 dataset. |
Hedgehog ligand biogenesis Gene Setproteins participating in the Hedgehog ligand biogenesis pathway from the Reactome Pathways 2024 dataset. |
Hh mutants abrogate ligand secretion Gene Setproteins participating in the Hh mutants abrogate ligand secretion pathway from the Reactome Pathways 2024 dataset. |
Hormone ligand-binding receptors Gene Setproteins participating in the Hormone ligand-binding receptors pathway from the Reactome Pathways 2024 dataset. |
IL-6-type cytokine receptor ligand interactions Gene Setproteins participating in the IL-6-type cytokine receptor ligand interactions pathway from the Reactome Pathways 2024 dataset. |
Ligand-receptor interactions Gene Setproteins participating in the Ligand-receptor interactions pathway from the Reactome Pathways 2024 dataset. |
Negative regulation of TCF-dependent signaling by WNT ligand antagonists Gene Setproteins participating in the Negative regulation of TCF-dependent signaling by WNT ligand antagonists pathway from the Reactome Pathways 2024 dataset. |
Peptide ligand-binding receptors Gene Setproteins participating in the Peptide ligand-binding receptors pathway from the Reactome Pathways 2024 dataset. |
Prostanoid ligand receptors Gene Setproteins participating in the Prostanoid ligand receptors pathway from the Reactome Pathways 2024 dataset. |
Regulation of TLR by endogenous ligand Gene Setproteins participating in the Regulation of TLR by endogenous ligand pathway from the Reactome Pathways 2024 dataset. |
Signaling by Ligand-Responsive EGFR Variants in Cancer Gene Setproteins participating in the Signaling by Ligand-Responsive EGFR Variants in Cancer pathway from the Reactome Pathways 2024 dataset. |
VEGF ligand-receptor interactions Gene Setproteins participating in the VEGF ligand-receptor interactions pathway from the Reactome Pathways 2024 dataset. |
WNT ligand biogenesis and trafficking Gene Setproteins participating in the WNT ligand biogenesis and trafficking pathway from the Reactome Pathways 2024 dataset. |
betaKlotho-mediated ligand binding Gene Setproteins participating in the betaKlotho-mediated ligand binding pathway from the Reactome Pathways 2024 dataset. |
positive regulation of chemokine (C-X-C motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of chemokine (C-X-C motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of chemokine (C-C motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of chemokine (C-C motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
chemokine (C-C motif) ligand 21 signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the chemokine (C-C motif) ligand 21 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of chemokine (C-X-C motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of chemokine (C-X-C motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
chemokine (C-X-C motif) ligand 12 signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the chemokine (C-X-C motif) ligand 12 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2025 genes participating in the extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2025 dataset. |
chemokine (C-C motif) ligand 2 signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the chemokine (C-C motif) ligand 2 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
chemokine (C-C motif) ligand 5 signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the chemokine (C-C motif) ligand 5 signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
sequestering of extracellular ligand from receptor Gene SetFrom GO Biological Process Annotations 2025 genes participating in the sequestering of extracellular ligand from receptor biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of chemokine (C-C motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of chemokine (C-C motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
signaling receptor ligand precursor processing Gene SetFrom GO Biological Process Annotations 2025 genes participating in the signaling receptor ligand precursor processing biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of chemokine (C-X-C motif) ligand 2 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of chemokine (C-X-C motif) ligand 2 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of chemokine (C-X-C motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of chemokine (C-X-C motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
epidermal growth factor receptor ligand maturation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the epidermal growth factor receptor ligand maturation biological process from the curated GO Biological Process Annotations 2025 dataset. |
positive regulation of chemokine (C-C motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the positive regulation of chemokine (C-C motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of chemokine (C-X-C motif) ligand 9 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of chemokine (C-X-C motif) ligand 9 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of chemokine (C-C motif) ligand 5 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of chemokine (C-C motif) ligand 5 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of signal transduction in absence of ligand Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of signal transduction in absence of ligand biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of extrinsic apoptotic signaling pathway in absence of ligand Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of extrinsic apoptotic signaling pathway in absence of ligand biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of tumor necrosis factor (ligand) superfamily member 11 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of tumor necrosis factor (ligand) superfamily member 11 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of chemokine (C-X-C motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of chemokine (C-X-C motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of chemokine (C-C motif) ligand 1 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of chemokine (C-C motif) ligand 1 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of chemokine (C-X-C motif) ligand 9 production Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of chemokine (C-X-C motif) ligand 9 production biological process from the curated GO Biological Process Annotations 2025 dataset. |
platelet-derived growth factor receptor-ligand complex Gene SetFrom GO Cellular Component Annotations 2025 proteins localized to the platelet-derived growth factor receptor-ligand complex cellular component from the curated GO Cellular Component Annotations 2025 dataset. |
transforming growth factor beta ligand-receptor complex Gene SetFrom GO Cellular Component Annotations 2025 proteins localized to the transforming growth factor beta ligand-receptor complex cellular component from the curated GO Cellular Component Annotations 2025 dataset. |
receptor ligand activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the receptor ligand activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
ligand-gated channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the ligand-gated channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential Gene SetFrom GO Molecular Function Annotations 2025 genes performing the ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
ligand-gated calcium channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the ligand-gated calcium channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
chemokine (C-C motif) ligand 7 binding Gene SetFrom GO Molecular Function Annotations 2025 genes performing the chemokine (C-C motif) ligand 7 binding molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
chemokine (C-C motif) ligand 5 binding Gene SetFrom GO Molecular Function Annotations 2025 genes performing the chemokine (C-C motif) ligand 5 binding molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
chemokine (C-C motif) ligand 19 binding Gene SetFrom GO Molecular Function Annotations 2025 genes performing the chemokine (C-C motif) ligand 19 binding molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
chemokine (C-C motif) ligand 21 binding Gene SetFrom GO Molecular Function Annotations 2025 genes performing the chemokine (C-C motif) ligand 21 binding molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
ligand-gated monoatomic cation channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the ligand-gated monoatomic cation channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
ligand-gated sodium channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the ligand-gated sodium channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
ligand-gated monoatomic anion channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the ligand-gated monoatomic anion channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
extracellular ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the extracellular ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
excitatory extracellular ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the excitatory extracellular ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
intracellularly ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the intracellularly ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
inhibitory extracellular ligand-gated monoatomic ion channel activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the inhibitory extracellular ligand-gated monoatomic ion channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
CD40 ligand deficiency Gene SetFrom DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease CD40 ligand deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset. |
Transforming growth factor beta ligand-receptor complex Gene SetFrom COMPARTMENTS Curated Protein Localization Evidence Scores 2025 proteins localized to the Transforming growth factor beta ligand-receptor complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset. |
Transforming growth factor beta ligand-receptor complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Transforming growth factor beta ligand-receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
platelet-derived growth factor receptor-ligand complex Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the platelet-derived growth factor receptor-ligand complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset. |
CD40 ligand levels Gene SetFrom GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the CD40 ligand levels phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. |
Neuroactive ligand-receptor interaction Gene SetFrom KEGG Pathways 2026 proteins participating in the Neuroactive ligand-receptor interaction pathway from the KEGG Pathways 2026 dataset. |
Neuroactive ligand signaling Gene SetFrom KEGG Pathways 2026 proteins participating in the Neuroactive ligand signaling pathway from the KEGG Pathways 2026 dataset. |
APELIN RECEPTOR EARLY ENDOGENOUS LIGAND Gene Setinteracting proteins for the APELIN RECEPTOR EARLY ENDOGENOUS LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
RECOMBINANT FLT3 LIGAND Gene Setinteracting proteins for the RECOMBINANT FLT3 LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
RECOMBINANT OX40 LIGAND Gene Setinteracting proteins for the RECOMBINANT OX40 LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
CD40 LIGAND Gene Setinteracting proteins for the CD40 LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
RECOMBINANT CD40-LIGAND Gene Setinteracting proteins for the RECOMBINANT CD40-LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
ADENOVIRUS 5-CD40 LIGAND Gene Setinteracting proteins for the ADENOVIRUS 5-CD40 LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
FMS-RELATED TYROSINE KINASE 3 LIGAND Gene Setinteracting proteins for the FMS-RELATED TYROSINE KINASE 3 LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
ADENOVIRAL TRANSDUCED HIL-12-EXPRESSING AUTOLOGOUS DENDRITIC CELLS INXN-3001 PLUS ACTIVATOR LIGAND INXN-1001 Gene Setinteracting proteins for the ADENOVIRAL TRANSDUCED HIL-12-EXPRESSING AUTOLOGOUS DENDRITIC CELLS INXN-3001 PLUS ACTIVATOR LIGAND INXN-1001 drug from theDGIdb Drug Targets 2026 dataset. |
PEPTIDE LIGAND 2 [PMID: 19055415] Gene Setinteracting proteins for the PEPTIDE LIGAND 2 [PMID: 19055415] drug from theDGIdb Drug Targets 2026 dataset. |
PD-1 LIGAND INHIBITOR Gene Setinteracting proteins for the PD-1 LIGAND INHIBITOR drug from theDGIdb Drug Targets 2026 dataset. |
NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 LIGAND 1 Gene Setinteracting proteins for the NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3 LIGAND 1 drug from theDGIdb Drug Targets 2026 dataset. |
PROGRAMMED CELL DEATH 1 LIGAND 1 Gene Setinteracting proteins for the PROGRAMMED CELL DEATH 1 LIGAND 1 drug from theDGIdb Drug Targets 2026 dataset. |
SELECTIN P LIGAND Gene Setinteracting proteins for the SELECTIN P LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
RANK LIGAND Gene Setinteracting proteins for the RANK LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
OX-40 LIGAND Gene Setinteracting proteins for the OX-40 LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
CD30 LIGAND Gene Setinteracting proteins for the CD30 LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
4-1BB LIGAND Gene Setinteracting proteins for the 4-1BB LIGAND drug from theDGIdb Drug Targets 2026 dataset. |
RECOMBINANT ADENOVIRUS 5 ENCODING TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND Gene Setinteracting proteins for the RECOMBINANT ADENOVIRUS 5 ENCODING TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGAND drug from theDGIdb Drug Targets 2026 dataset. |