| Name |
|---|
|
|
|
coronary artery disease;
|
|
brugada syndrome;
|
|
|
cardiomyopathy, dilated; dcm - dilated cardiomyopathy;
|
|
arrhythmias, cardiac;
|
fetal
|
chronic renal failure;
|
|
|
arrhythmias, cardiac; brugada syndrome; cardiomyopathies; channelopathies;
|
brugada syndrome; chromosome deletion;
|
arrhythmogenic right ventricular dysplasia;
|
|
|
cardiomyopathy, hypertrophic;
|
anterior wall myocardial infarction; arrhythmias, cardiac;
|
Caspase activation via
|
|
activation
|
activation
|
Linker-for-activation
|
Activation
|
Activation
|
Activation
|
Activation
|
TMEM88B_KD_GPL10558_471_human_cardiovascular progenitors
|
primary adaptive immune response involving T
|
adaptive immune memory response involving T
|
primary adaptive immune response involving T
|
regulation
|
negative regulation
|
positive regulation
|
t
|
positive regulation
|
T
|
negative regulation
|
regulation
|
positive regulation
|
T
|
negative regulation
|
regulation
|
regulation
|
ectopic germ
|
retinal
|
negative regulation
|
positive regulation
|
regulation
|
positive regulation
|
cytotoxic T
|
regulation
|
ischemic neuronal
|
regulation
|
positive regulation
|
negative regulation
|
mitochondrial outer membrane permeabilization involved in programmed
|
negative regulation
|
positive regulation
|
programmed necrotic
|
negative regulation
|
positive regulation by organism
|
modulation
|
positive regulation
|
developmental programmed
|
regulation
|
necrotic
|
positive regulation by symbiont
|
negative regulation
|
|
negative regulation by organism
|
regulation
|
positive regulation
|
modulation by symbiont
|
modulation
|
induction
|
autophagic
|
regulation
|
regulation
|
negative regulation by symbiont
|
programmed
|
|
Programmed
|
abnormal interdigital
|
abnormal
|
decreased
|
increased
|
|
Stimulation
|
TRIF-mediated programmed
|
NRIF signals
|
Programmed
|
positive regulation
|
negative regulation
|
negative regulation
|
negative regulation
|
positive regulation
|
regulation
|
negative regulation
|
positive regulation
|
negative regulation
|
regulation
|
mitochondrial outer membrane permeabilization involved in programmed
|
autophagic
|
positive regulation
|
programmed
|
regulation
|
programmed necrotic
|
induction
|
negative regulation
|
regulation
|
positive regulation
|
regulation
|
hydrogen peroxide-mediated programmed
|
positive regulation
|
regulation
|
regulation
|
abnormal
|
increased
|
abnormal interdigital
|
decreased
|
Nanoparticle triggered autophagic
|
|
Diseases
|
FOXO-mediated transcription
|
NRIF signals
|
Programmed
|
Regulation
|
SARS-CoV-1-mediated effects on programmed
|
Stimulation
|
TLR3-mediated TICAM1-dependent programmed
|
TP53 Regulates Transcription
|
TP53 regulates transcription
|
TRIF-mediated programmed
|
negative regulation
|
negative regulation
|
pyroptotic
|
positive regulation
|
regulation
|
negative regulation
|
regulation
|
mitochondrial outer membrane permeabilization involved in programmed
|
autophagic
|
positive regulation
|
programmed
|
regulation
|
positive regulation
|
programmed necrotic
|
induction
|
negative regulation
|
hydrogen peroxide-mediated programmed
|
regulation
|
regulation
|
PROGRAMMED CELL DEATH 1 LIGAND 1 Gene Setinteracting proteins for the PROGRAMMED CELL DEATH 1 LIGAND 1 drug from theDGIdb Drug Targets 2026 dataset. |
adenocarcinoma; carcinoma, large
|
cerebellar purkinje
|
cerebellar Purkinje
|
the co-stimulatory signal during t-
|
activation
|
il-2 receptor beta chain in t
|
|
nk t
|
positive regulation
|
regulation
|
negative regulation
|
positive regulation
|
myeloid
|
regulation
|
positive regulation
|
negative regulation
|
t
|
positive regulation
|
positive regulation
|
b
|
alpha-beta t
|
endothelial
|
microglial
|
positive regulation
|
negative regulation
|
positive regulation
|
positive regulation
|
regulation
|
myeloid dendritic
|
t
|
hepatic stellate
|
regulation
|
positive regulation
|
negative regulation
|
mast
|
gamma-delta t
|
positive regulation
|
memory t
|
regulation
|
cd8-positive, alpha-beta t
|
regulation
|
regulation
|
regulation
|
regulation
|
negative regulation
|
positive regulation
|
alpha-beta t
|
negative regulation
|
natural killer
|
regulation
|
regulation
|
regulation
|
mast
|
cd4-positive, alpha-beta t
|
regulation
|
negative regulation
|
natural killer
|
positive regulation
|
regulation
|
positive regulation
|
positive regulation
|
regulation
|
regulation
|
negative regulation
|
negative regulation
|
myeloid dendritic
|
|
follicular dendritic
|
positive regulation
|
negative regulation
|
microglial
|
negative regulation
|
skeletal muscle satellite
|
t-helper 2
|
b
|
negative regulation
|
positive regulation
|
positive regulation
|
regulation
|
regulation
|
decreased t
|
defective b
|
T-
|
abnormal microglial
|
abnormal t
|
abnormal b
|
T
|
B
|
Transcriptional activation
|
Monoclonal Mast
|
Decreased T
|
Defective B
|
alpha-beta T
|
negative regulation
|
positive regulation
|
positive regulation
|
negative regulation
|
gamma-delta T
|
natural killer
|
T
|
B
|
negative regulation
|
regulation
|
regulation
|
microglial
|
positive regulation
|
microglial
|
regulation
|
negative regulation
|
B
|
positive regulation
|
CD8-positive, alpha-beta T
|
positive regulation
|
positive regulation
|
positive regulation
|
regulation
|
positive regulation
|
negative regulation
|
myeloid dendritic
|
T-helper 1
|
positive regulation
|
mast
|
T
|
regulation
|
negative regulation
|
memory T
|
T-helper 2
|
regulation
|
positive regulation
|
positive regulation
|
negative regulation
|
positive regulation
|
positive regulation
|
myeloid dendritic
|
regulation
|
positive regulation
|
positive regulation
|
CD4-positive, alpha-beta T
|
negative regulation
|
negative regulation
|
negative regulation
|
positive regulation
|
negative regulation
|
positive regulation
|
natural killer
|
positive regulation
|
endothelial
|
positive regulation
|
negative regulation
|
negative regulation
|
regulation
|
mast
|
myeloid
|
regulation
|
regulation
|
regulation
|
positive regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
NK T
|
abnormal T
|
decreased microglial
|
abnormal B
|
increased microglial
|
abnormal microglial
|
Modulators
|
T
|
mRNA vaccine activation
|
Extrafollicular and follicular B
|
Transcriptional activation
|
negative regulation
|
positive regulation
|
positive regulation
|
negative regulation
|
natural killer
|
T
|
B
|
negative regulation
|
NK T
|
regulation
|
regulation
|
microglial
|
positive regulation
|
microglial
|
negative regulation
|
regulation
|
negative regulation
|
alpha-beta T
|
B
|
positive regulation
|
CD8-positive, alpha-beta T
|
positive regulation
|
positive regulation
|
positive regulation
|
regulation
|
positive regulation
|
gamma-delta T
|
myeloid dendritic
|
T-helper 1
|
positive regulation
|
mast
|
negative regulation
|
positive regulation
|
T
|
regulation
|
negative regulation
|
negative regulation
|
memory T
|
T-helper 2
|
regulation
|
positive regulation
|
negative regulation
|
positive regulation
|
positive regulation
|
myeloid dendritic
|
regulation
|
positive regulation
|
positive regulation
|
CD4-positive, alpha-beta T
|
satellite
|
negative regulation
|
negative regulation
|
positive regulation
|
negative regulation
|
positive regulation
|
natural killer
|
positive regulation
|
endothelial
|
positive regulation
|
negative regulation
|
regulation
|
mast
|
myeloid
|
regulation
|
regulation
|
regulation
|
positive regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
regulation
|
NOTCH_INHIBITION_GDS2794_61_human_MOLT4 (T-
|
SOX11_DEPLETION_GDS4801_326_human_Z138 mantle
|
increased number
|
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem
|
H3K36me3_Mesenchymal Stem
|
H3K4me3_Bone Marrow Derived Mesenchymal Stem
|
H3K27me3_Bone Marrow Derived Mesenchymal Stem
|
H3K36me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem
|
H3K4me1_Bone Marrow Derived Mesenchymal Stem
|
H3K4me3_Mesenchymal Stem
|
H3K9me3_Mesenchymal Stem
|
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem
|
H3K4me1_Adipose Derived Mesenchymal Stem
|
H3K27me3_Adipose Derived Mesenchymal Stem
|
H3K27me3_Mesenchymal Stem
|
H3K9ac_Mesenchymal Stem
|
H3K9me3_Adipose Derived Mesenchymal Stem
|
H3K36me3_Bone Marrow Derived Mesenchymal Stem
|
H3K9ac_Adipose Derived Mesenchymal Stem
|
H3K36me3_Adipose Derived Mesenchymal Stem
|
H3K9ac_Bone Marrow Derived Mesenchymal Stem
|
H3K27me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem
|
H3K4me1_Mesenchymal Stem
|
H3K9me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem
|
H3K9me3_Bone Marrow Derived Mesenchymal Stem
|
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem
|
H3K4me3_Adipose Derived Mesenchymal Stem
|
Corneal endothelial
|
AUTOLOGOUS PROSTATE STEM CELL ANTIGEN-SPECIFIC CAR T CELLS BPX-601 Gene Setinteracting proteins for the AUTOLOGOUS PROSTATE STEM CELL ANTIGEN-SPECIFIC CAR T CELLS BPX-601 drug from theDGIdb Drug Targets 2026 dataset. |
induction
|
Sudden cardiac
|
Growth retardation, developmental delay, coarse facies, and early
|
Sudden infant
|
|
cd95
|
cd95
|
|
trail
|
|
|
Fetal
|
|
Sudden Infant
|
Sudden Infant
|
Growth Retardation, Developmental Delay, Coarse Facies, And Early
|
|
sudden infant
|
myocardial infarct; cardiac
|
coronary artery disease;
|
coronary artery disease; sudden cardiac
|
coronary artery disease;
|
arrhythmias, cardiac; brugada syndrome;
|
|
sids/sudden infant
|
heart disease, ischemic; myocardial infarction; sudden cardiac
|
cardiac
|
myocardial infarct; depression; cardiac
|
cardiac
|
abnormalities, multiple; arrhythmias, cardiac; autonomic nervous system diseases;
|
sudden infant
|
abruptio placentae; fetal
|
|
arrhythmias, cardiac; sudden infant
|
coronary artery disease;
|
myocardial infarction; sudden cardiac
|
fetal
|
sudden cardiac
|
birth weight; sudden infant
|
embryo loss; fetal
|
cardiovascular diseases;
|
fetal
|
anemia; brain
|
coronary disease;
|
cardiac arrhythmias and sudden
|
atrial septal defects;
|
abortion, spontaneous; abruptio placentae; fetal
|
staphylococcal infections; sudden infant
|
|
gonadal dysgenesis, 46,xy; infertility, male; sudden infant
|
sudden infant
|
cadaver; cardiovascular diseases;
|
early onset
|
cardiomyopathy; heart failure; sudden
|
|
cardiovascular
|
atrioventricular block;
|
infection; sudden infant
|
coronary disease;
|
long qt syndrome; sudden infant
|
complication, cardiovascular pregnancy; fetal
|
|
arrhythmias, cardiac; cardiomyopathy, dilated;
|
anoxia; sudden infant
|
abruptio placentae; fetal
|
fetal
|
arrhythmias, cardiac;
|
|
arrhythmias, cardiac;
|
cardiomyopathy, hypertrophic;
|
arrhythmias, cardiac;
|
lipid metabolism, inborn errors; sudden infant
|
coronary disease; coronary heart disease;
|
sudden infant
|
|
regulation
|
negative regulation
|
|
negative regulation
|
extrinsic apoptotic signaling pathway via
|
neuron
|
|
positive regulation
|
positive regulation
|
regulation
|
negative regulation
|
regulation
|
|
cd95
|
|
|
|
|
Aging (time to
|
sudden cardiac
|
time
|
sudden
|
sudden cardiac
|
neonatal
|
|
|
time
|
sudden
|
|
Brain
|
|
|
Fetal
|
|
Sudden Infant
|
|
|
|
Domain
|
|
BH3-interacting domain
|
|
premature
|
pregnancy-related premature
|
{sudden infant
|
sudden infant
|
growth retardation, developmental delay, coarse facies, and early
|
|
|
NADE modulates
|
NRAGE signals
|
Sudden Unexplained
|
Sudden Infant
|
Growth Retardation, Developmental Delay, Coarse Facies, And Early
|
Sudden Unexplained
|
Sudden Unexpected Nocturnal
|
Sudden Unexplained Infant
|
Sudden Infant
|
|
|
Sudden Cardiac
|
Sudden
|
|
Increased Risk
|
Cardiac
|
Determination
|
Neonatal
|
|
Embryo
|
Brain
|
Near Sudden Infant
|
Unexplained Sudden
|
Perinatal
|
Aborted Sudden Cardiac
|
Sudden Arrhythmic
|
Infant
|
extrinsic apoptotic signaling pathway via
|
negative regulation
|
regulation
|
negative regulation
|
positive regulation
|
positive regulation
|
regulation
|
|
negative regulation
|
regulation
|
|
CD95
|
|
|
|
|
|
premature
|
pregnancy-related premature
|
sudden unexpected
|
Sudden infant
|
|
NADE modulates
|
NRAGE signals
|
TP53 Regulates Transcription
|
extrinsic apoptotic signaling pathway via
|
negative regulation
|
positive regulation
|
regulation
|
|
negative regulation
|
regulation
|
|
CD95
|
|
|
|
|
|
Sudden infant
|
|
CD95
|
|
CD95
|
TRAIL
|
Sudden unexplained
|
SUDDEN INFANT DEATH SYNDR Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the SUDDEN INFANT DEATH SYNDR phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
Sudden cardiac
|
|
Family history
|
Neurodegenerative illness progressing to crippling dystonia and
|
Neonatal
|
Sudden infant
|
|
Sudden unexplained
|
Cardiovascular
|
Cardiovascular
|
Aging (time to
|
Parental longevity (mother's age at
|
Parental longevity (father's age at
|
Parental longevity (combined parental age at
|
Infant, child and juvenile
|
Parental longevity (mother's age at
|
carcinoma, basal
|
carcinoma, basal
|
b-
|
adenocarcinoma; carcinoma, large
|
carcinoma, basal
|
carcinoma, basal
|
carcinoma, basal
|
adenocarcinoma; carcinoma, small
|
carcinoma, basal
|
carcinoma, basal
|
adenocarcinoma; carcinoma, giant
|
|
non-small
|
role
|
angiotensin ii mediated activation
|
role
|
ca-calmodulin-dependent protein kinase activation Gene SetFrom Biocarta Pathways proteins participating in the ca-calmodulin-dependent protein kinase activation pathway from the Biocarta Pathways dataset. |
transcriptional activation
|
activation
|
lck and fyn tyrosine kinases in initiation
|
aspirin blocks signaling pathway involved in platelet activation Gene SetFrom Biocarta Pathways proteins participating in the aspirin blocks signaling pathway involved in platelet activation pathway from the Biocarta Pathways dataset. |
intrinsic prothrombin activation pathway Gene SetFrom Biocarta Pathways proteins participating in the intrinsic prothrombin activation pathway pathway from the Biocarta Pathways dataset. |
extrinsic prothrombin activation pathway Gene SetFrom Biocarta Pathways proteins participating in the extrinsic prothrombin activation pathway pathway from the Biocarta Pathways dataset. |
activation
|
nfkb activation by nontypeable hemophilus influenzae Gene SetFrom Biocarta Pathways proteins participating in the nfkb activation by nontypeable hemophilus influenzae pathway from the Biocarta Pathways dataset. |
Macrophage Activation Syndrome Gene SetFrom CTD Gene-Disease Associations genes/proteins associated with the disease Macrophage Activation Syndrome from the curated CTD Gene-Disease Associations dataset. |
activation
|
reduced trans-activation impaired sperm production and male infertility Gene SetFrom GAD Gene-Disease Associations genes associated with the disease reduced trans-activation impaired sperm production and male infertility in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
negative regulation
|
activation
|
negative regulation
|
activation
|
negative regulation
|
positive regulation
|
integrin activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the integrin activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
complement activation, classical pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the complement activation, classical pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation
|
activation
|
neutrophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the neutrophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation
|
astrocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the astrocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation
|
activation
|
regulation
|
regulation
|
activation
|
regulation
|
regulation
|
activation
|
activation
|
activation
|
eosinophil activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the eosinophil activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation
|
neutrophil activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the neutrophil activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
activation
|
regulation
|
activation
|
negative regulation
|
basophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the basophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
keratinocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the keratinocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation
|
activation
|
complement activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the complement activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation
|
regulation
|
positive regulation
|
activation
|
activation
|
eosinophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the eosinophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation
|
regulation
|
negative regulation
|
complement activation, lectin pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the complement activation, lectin pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
macrophage activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the macrophage activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
regulation
|
leukocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the leukocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation
|
transcriptional activation by promoter-enhancer looping Gene SetFrom GO Biological Process Annotations 2015 genes participating in the transcriptional activation by promoter-enhancer looping biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation
|
carbon catabolite activation
|
leukocyte adhesive activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the leukocyte adhesive activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation
|
activation
|
activation
|
positive regulation
|
monocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the monocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation
|
activation
|
activation
|
factor xii activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the factor xii activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation
|
regulation
|
positive regulation
|
amino acid activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the amino acid activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
plasminogen activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the plasminogen activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
complement activation, alternative pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the complement activation, alternative pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
platelet activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the platelet activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation
|
nitrogen catabolite activation
|
regulation
|
fibroblast activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the fibroblast activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
egg activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the egg activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation
|
activation
|
macrophage activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the macrophage activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
negative regulation
|
nitrogen catabolite activation
|
negative regulation
|
transforming growth factor beta activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the transforming growth factor beta activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation
|
zymogen activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the zymogen activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
myeloid leukocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the myeloid leukocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
protein activation cascade Gene SetFrom GO Biological Process Annotations 2015 genes participating in the protein activation cascade biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation
|
activation
|
activation
|
activation
|
trypsinogen activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the trypsinogen activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation
|
positive regulation
|
granulocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the granulocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
positive regulation
|
regulation
|
negative regulation
|
activation
|
lymphocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the lymphocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
basophil activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the basophil activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
negative regulation
|
carbon catabolite activation
|
lymphocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the lymphocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
leukocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the leukocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
factor x activation deficiency Gene SetFrom HPO Gene-Disease Associations genes associated with the factor x activation deficiency phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset. |
Macrophage Activation Syndrome Gene SetFrom HuGE Navigator Gene-Phenotype Associations genes associated with the Macrophage Activation Syndrome phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset. |
sulfate activation for sulfonation Gene SetFrom HumanCyc Pathways proteins participating in the sulfate activation for sulfonation pathway from the HumanCyc Pathways dataset. |
fatty acid activation Gene SetFrom HumanCyc Pathways proteins participating in the fatty acid activation pathway from the HumanCyc Pathways dataset. |
Smad anchor for receptor activation, Smad-binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Smad anchor for receptor activation, Smad-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Vitamin B12-dependent methionine synthase, activation domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Vitamin B12-dependent methionine synthase, activation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Signal transducer and activation
|
Mediator complex, subunit Med25, PTOV activation and synapsin 2 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Mediator complex, subunit Med25, PTOV activation and synapsin 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
RFX1 transcription activation region Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the RFX1 transcription activation region protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Hox9, N-terminal activation domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Hox9, N-terminal activation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Rho GTPase activation protein Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Rho GTPase activation protein protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Cytoplasmic activation/proliferation-associated protein-1 C term Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Cytoplasmic activation/proliferation-associated protein-1 C term protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Nuclear respiratory factor-1, activation binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Nuclear respiratory factor-1, activation binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Recombination-activation protein 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Recombination-activation protein 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Caudal-like activation domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Caudal-like activation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Signalling lymphocyte activation molecule family receptors Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Signalling lymphocyte activation molecule family receptors protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Signal transducer and activation
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Signaling lymphocytic activation molecule, N-terminal Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Signaling lymphocytic activation molecule, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMUGS_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMUGS_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_PC3_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_PC3_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_SKM1_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_SKM1_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_VCAP_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_VCAP_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_24.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_24.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMGI_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMGI_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
abnormal macrophage activation involved in immune response Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal macrophage activation involved in immune response phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal platelet activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal platelet activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal locomotor activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal locomotor activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal thymocyte activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal thymocyte activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
Hypoxia response via HIF activation Gene SetFrom PANTHER Pathways proteins participating in the Hypoxia response via HIF activation pathway from the PANTHER Pathways dataset. |
Regulation
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Validated targets
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MAP kinase activation in TLR cascade Gene Setproteins participating in the MAP kinase activation in TLR cascade pathway from the Reactome Pathways dataset. |
Alternative complement activation Gene Setproteins participating in the Alternative complement activation pathway from the Reactome Pathways dataset. |
Activation
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Activation
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Activation
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WNT mediated activation
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GPVI-mediated activation cascade Gene Setproteins participating in the GPVI-mediated activation cascade pathway from the Reactome Pathways dataset. |
NGF-independant TRKA activation Gene Setproteins participating in the NGF-independant TRKA activation pathway from the Reactome Pathways dataset. |
FCERI mediated NF-kB activation Gene Setproteins participating in the FCERI mediated NF-kB activation pathway from the Reactome Pathways dataset. |
GABA A (rho) receptor activation Gene Setproteins participating in the GABA A (rho) receptor activation pathway from the Reactome Pathways dataset. |
Axonal growth inhibition (RHOA activation) Gene Setproteins participating in the Axonal growth inhibition (RHOA activation) pathway from the Reactome Pathways dataset. |
Activation
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Nuclear Events (kinase and transcription factor activation) Gene Setproteins participating in the Nuclear Events (kinase and transcription factor activation) pathway from the Reactome Pathways dataset. |
Activation
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Activation
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ERK2 activation Gene Setproteins participating in the ERK2 activation pathway from the Reactome Pathways dataset. |
Activation
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CREB phosphorylation through the activation
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Activation
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Activation
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Activation
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Activation
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Post NMDA receptor activation events Gene Setproteins participating in the Post NMDA receptor activation events pathway from the Reactome Pathways dataset. |
ARMS-mediated activation Gene Setproteins participating in the ARMS-mediated activation pathway from the Reactome Pathways dataset. |
FCERI mediated MAPK activation Gene Setproteins participating in the FCERI mediated MAPK activation pathway from the Reactome Pathways dataset. |
Activation, myristolyation
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Gamma carboxylation, hypusine formation and arylsulfatase activation Gene Setproteins participating in the Gamma carboxylation, hypusine formation and arylsulfatase activation pathway from the Reactome Pathways dataset. |
RIP-mediated NFkB activation via ZBP1 Gene Setproteins participating in the RIP-mediated NFkB activation via ZBP1 pathway from the Reactome Pathways dataset. |
GABA receptor activation Gene Setproteins participating in the GABA receptor activation pathway from the Reactome Pathways dataset. |
Transcriptional activation
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Activation
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Activation
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Activation
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Activation
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TRAF6 mediated induction
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TRAF6 mediated NF-kB activation Gene Setproteins participating in the TRAF6 mediated NF-kB activation pathway from the Reactome Pathways dataset. |
Activation
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GP1b-IX-V activation signalling Gene Setproteins participating in the GP1b-IX-V activation signalling pathway from the Reactome Pathways dataset. |
Cam-PDE 1 activation Gene Setproteins participating in the Cam-PDE 1 activation pathway from the Reactome Pathways dataset. |
Activation
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Activation
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RSK activation Gene Setproteins participating in the RSK activation pathway from the Reactome Pathways dataset. |
Frs2-mediated activation Gene Setproteins participating in the Frs2-mediated activation pathway from the Reactome Pathways dataset. |
TRAF6 mediated IRF7 activation Gene Setproteins participating in the TRAF6 mediated IRF7 activation pathway from the Reactome Pathways dataset. |
Activation
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Unblocking
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Activation, translocation and oligomerization
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FGFR3c ligand binding and activation Gene Setproteins participating in the FGFR3c ligand binding and activation pathway from the Reactome Pathways dataset. |
MEK activation Gene Setproteins participating in the MEK activation pathway from the Reactome Pathways dataset. |
Activation
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Vitamins B6 activation to pyridoxal phosphate Gene Setproteins participating in the Vitamins B6 activation to pyridoxal phosphate pathway from the Reactome Pathways dataset. |
Activation
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Ras activation uopn Ca2+ infux through NMDA receptor Gene Setproteins participating in the Ras activation uopn Ca2+ infux through NMDA receptor pathway from the Reactome Pathways dataset. |
CREB phosphorylation through the activation
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PKA activation in glucagon signalling Gene Setproteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways dataset. |
Activation
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Activation
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The activation
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TRAF3-dependent IRF activation pathway Gene Setproteins participating in the TRAF3-dependent IRF activation pathway pathway from the Reactome Pathways dataset. |
FGFR1c ligand binding and activation Gene Setproteins participating in the FGFR1c ligand binding and activation pathway from the Reactome Pathways dataset. |
Aflatoxin activation and detoxification Gene Setproteins participating in the Aflatoxin activation and detoxification pathway from the Reactome Pathways dataset. |
Processing and activation
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FGFR1c and Klotho ligand binding and activation Gene Setproteins participating in the FGFR1c and Klotho ligand binding and activation pathway from the Reactome Pathways dataset. |
Activation
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ERK activation Gene Setproteins participating in the ERK activation pathway from the Reactome Pathways dataset. |
Prolonged ERK activation events Gene Setproteins participating in the Prolonged ERK activation events pathway from the Reactome Pathways dataset. |
Transcriptional activation
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activated TAK1 mediates p38 MAPK activation Gene Setproteins participating in the activated TAK1 mediates p38 MAPK activation pathway from the Reactome Pathways dataset. |
Activation
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Activation
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G-protein activation Gene Setproteins participating in the G-protein activation pathway from the Reactome Pathways dataset. |
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling Gene Setproteins participating in the TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling pathway from the Reactome Pathways dataset. |
SHC activation Gene Setproteins participating in the SHC activation pathway from the Reactome Pathways dataset. |
FGFR3 ligand binding and activation Gene Setproteins participating in the FGFR3 ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR3b ligand binding and activation Gene Setproteins participating in the FGFR3b ligand binding and activation pathway from the Reactome Pathways dataset. |
IRF3 mediated activation
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Platelet activation, signaling and aggregation Gene Setproteins participating in the Platelet activation, signaling and aggregation pathway from the Reactome Pathways dataset. |
NOTCH2 Activation and Transmission
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Activation and oligomerization
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FGFR2 ligand binding and activation Gene Setproteins participating in the FGFR2 ligand binding and activation pathway from the Reactome Pathways dataset. |
PI3K/AKT activation Gene Setproteins participating in the PI3K/AKT activation pathway from the Reactome Pathways dataset. |
FGFR2c ligand binding and activation Gene Setproteins participating in the FGFR2c ligand binding and activation pathway from the Reactome Pathways dataset. |
CREB phosphorylation through the activation
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Activation
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Activation
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GABA A receptor activation Gene Setproteins participating in the GABA A receptor activation pathway from the Reactome Pathways dataset. |
eNOS activation and regulation Gene Setproteins participating in the eNOS activation and regulation pathway from the Reactome Pathways dataset. |
Caspase-8 activation by cleavage Gene Setproteins participating in the Caspase-8 activation by cleavage pathway from the Reactome Pathways dataset. |
Activation
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PKA activation Gene Setproteins participating in the PKA activation pathway from the Reactome Pathways dataset. |
FGFR1b ligand binding and activation Gene Setproteins participating in the FGFR1b ligand binding and activation pathway from the Reactome Pathways dataset. |
Activation
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TAK1 activates NFkB by phosphorylation and activation
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TRKA activation by NGF Gene Setproteins participating in the TRKA activation by NGF pathway from the Reactome Pathways dataset. |
Lectin pathway
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Glutamate Binding, Activation
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FGFR2b ligand binding and activation Gene Setproteins participating in the FGFR2b ligand binding and activation pathway from the Reactome Pathways dataset. |
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Gene Setproteins participating in the NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 pathway from the Reactome Pathways dataset. |
Activation
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HSF1 activation Gene Setproteins participating in the HSF1 activation pathway from the Reactome Pathways dataset. |
RAF activation Gene Setproteins participating in the RAF activation pathway from the Reactome Pathways dataset. |
IRAK2 mediated activation
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Classical antibody-mediated complement activation Gene Setproteins participating in the Classical antibody-mediated complement activation pathway from the Reactome Pathways dataset. |
IRAK2 mediated activation
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ERK1 activation Gene Setproteins participating in the ERK1 activation pathway from the Reactome Pathways dataset. |
eNOS activation Gene Setproteins participating in the eNOS activation pathway from the Reactome Pathways dataset. |
AMPK inhibits chREBP transcriptional activation activity Gene Setproteins participating in the AMPK inhibits chREBP transcriptional activation activity pathway from the Reactome Pathways dataset. |
FGFR4 ligand binding and activation Gene Setproteins participating in the FGFR4 ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR ligand binding and activation Gene Setproteins participating in the FGFR ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR1 ligand binding and activation Gene Setproteins participating in the FGFR1 ligand binding and activation pathway from the Reactome Pathways dataset. |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Gene Setproteins participating in the JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 pathway from the Reactome Pathways dataset. |
CREB phosphorylation through the activation
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Activation
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Activation
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IRS activation Gene Setproteins participating in the IRS activation pathway from the Reactome Pathways dataset. |
FCGR activation Gene Setproteins participating in the FCGR activation pathway from the Reactome Pathways dataset. |
GABA B receptor activation Gene Setproteins participating in the GABA B receptor activation pathway from the Reactome Pathways dataset. |
Complement Activation, Classical Pathway(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Complement Activation, Classical Pathway(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
Transcriptional activation by NRF2(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Transcriptional activation by NRF2(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
Complement Activation, Classical Pathway(Mus musculus) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Complement Activation, Classical Pathway(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset. |
Nanoparticle-mediated activation
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Macrophage Activation Syndrome Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Macrophage Activation Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Systemic Immune Activation Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Systemic Immune Activation in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Activation
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Factor X Activation Deficiency Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype Factor X Activation Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
positive regulation
|
activation
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activation
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complement activation, lectin pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the complement activation, lectin pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation
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macrophage activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the macrophage activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
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activation
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integrin activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the integrin activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
basophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the basophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
monocyte activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the monocyte activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
|
activation
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activation
|
activation
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regulation
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positive regulation
|
activation
|
activation
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monocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the monocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
macrophage activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the macrophage activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation
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activation
|
activation
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plasminogen activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the plasminogen activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation
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complement activation, classical pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the complement activation, classical pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
zymogen activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the zymogen activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
complement activation, alternative pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the complement activation, alternative pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
Factor XII activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the Factor XII activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation
|
regulation
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negative regulation
|
positive regulation
|
positive regulation
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negative regulation
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negative regulation
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astrocyte activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the astrocyte activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
positive regulation
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negative regulation
|
activation
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negative regulation
|
activation
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neutrophil activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the neutrophil activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation
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astrocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the astrocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation
|
regulation
|
regulation
|
activation
|
regulation
|
negative regulation
|
negative regulation
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