Enzymatic degradation of dopamine by COMT

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Results for "Enzymatic degradation of dopamine by COMT": 24 genes, 432 gene sets

Name
COMT Gene catechol-O-methyltransferase Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]
DBH Gene dopamine beta-hydroxylase (dopamine beta-monooxygenase) The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. [provided by RefSeq, Aug 2017]
P3H4 Gene prolyl 3-hydroxylase family member 4 (non-enzymatic) This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes. [provided by RefSeq, Jul 2008]
UFD1L Gene ubiquitin fusion degradation* 1 like (yeast)* The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]
LOC440489 Gene ubiquitin fusion degradation* 1 like (yeast) pseudogene*
ERMARD Gene ER membrane-associated RNA degradation The protein encoded by this gene contains 2 transmembrane domains near the C-terminus and is localized in the endoplasmic reticulum. Knockout of this gene in developing rat brain showed that it may be involved in neuronal migration. Mutations in this gene are associated with periventricular nodular heterotopia-6 (PVNH6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
EDEM2 Gene ER degradation* enhancer, mannosidase alpha-like 2* In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]
EDEM3 Gene ER degradation* enhancer, mannosidase alpha-like 3* Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]
EDEM1 Gene ER degradation* enhancer, mannosidase alpha-like 1* Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive regulation of retrograde protein transport, ER to cytosol; protein targeting to ER; and proteolysis involved in protein catabolic process. Located in aggresome and endoplasmic reticulum quality control compartment. [provided by Alliance of Genome Resources, Mar 2025]
UFD1 Gene ubiquitin recognition factor in ER associated degradation* 1* The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]
PGBDF Gene plakoglobin binding and degradation* factor*
LOC101929815 Gene D(1B) dopamine* receptor-like*
DRD5P1 Gene dopamine receptor D5 pseudogene 1
DRD5P2 Gene dopamine receptor D5 pseudogene 2
DRD4 Gene dopamine receptor D4 This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]
DRD5 Gene dopamine receptor D5 This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]
DRD2 Gene dopamine receptor D2 This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
DRD3 Gene dopamine receptor D3 This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008]
DRD1 Gene dopamine receptor D1 This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
LOC101060524 Gene D(1B) dopamine* receptor-like*
LOC105369284 Gene D(1B) dopamine* receptor-like*
CDNF Gene cerebral dopamine* neurotrophic factor* Predicted to enable growth factor activity. Predicted to be involved in dopaminergic neuron differentiation and neuron projection development. Predicted to be located in extracellular region. Predicted to be active in endoplasmic reticulum and extracellular space. [provided by Alliance of Genome Resources, Mar 2025]
LOC102724390 Gene D(1B) dopamine* receptor-like*
DORIP1 Gene dopamine receptor interacting protein 1 Predicted to act upstream of or within with a positive effect on NMDA selective glutamate receptor signaling pathway and cAMP-mediated signaling. Predicted to act upstream of or within several processes, including G protein-coupled dopamine receptor signaling pathway; memory; and neurogenesis. [provided by Alliance of Genome Resources, Mar 2025]
Enzymatic degradation of dopamine by COMT Gene Set From Reactome Pathways 2014 proteins participating in the Enzymatic degradation of dopamine by COMT pathway from the Reactome Pathways dataset.
Enzymatic degradation of dopamine by COMT Gene Set From Reactome Pathways 2024 proteins participating in the Enzymatic degradation of dopamine by COMT pathway from the Reactome Pathways 2024 dataset.
Enzymatic degradation of Dopamine by monoamine oxidase Gene Set From Reactome Pathways 2014 proteins participating in the Enzymatic degradation of Dopamine by monoamine oxidase pathway from the Reactome Pathways dataset.
Enzymatic degradation of Dopamine by monoamine oxidase Gene Set From Reactome Pathways 2024 proteins participating in the Enzymatic degradation of Dopamine by monoamine oxidase pathway from the Reactome Pathways 2024 dataset.
comt Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term comt in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
O-methyltransferase COMT-type Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the O-methyltransferase COMT-type protein domain from the InterPro Predicted Protein Domain Annotations dataset.
COMT Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for COMT from the Pathway Commons Protein-Protein Interactions dataset.
COMT Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the COMT gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
COMT Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the COMT gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
dopamine degradation Gene Set From HumanCyc Pathways proteins participating in the dopamine degradation pathway from the HumanCyc Pathways dataset.
temperature-sensitive enzymatic activity Gene Set From GAD Gene-Disease Associations genes associated with the disease temperature-sensitive enzymatic activity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
cyp1a2 enzymatic activity Gene Set From GAD Gene-Disease Associations genes associated with the disease cyp1a2 enzymatic activity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
enzymatic Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term enzymatic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
heparan sulfate proteoglycan biosynthetic process, enzymatic modification Gene Set From GO Biological Process Annotations 2015 genes participating in the heparan sulfate proteoglycan biosynthetic process, enzymatic modification biological process from the curated GO Biological Process Annotations 2015 dataset.
heparan sulfate proteoglycan biosynthetic process, enzymatic modification Gene Set From GO Biological Process Annotations 2023 genes participating in the heparan sulfate proteoglycan biosynthetic process, enzymatic modification biological process from the curated GO Biological Process Annotations 2023 dataset.
Dopamine beta hydroxylase deficiency Gene Set From ClinVar Gene-Phenotype Associations genes associated with the Dopamine beta hydroxylase deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.
dopamine-491 Gene Set From CMAP Signatures of Differentially Expressed Genes for Small Molecules genes differentially expressed following the dopamine-491 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Dopamine Gene Set From CTD Gene-Chemical Interactions genes/proteins interacting with the chemical Dopamine from the curated CTD Gene-Chemical Interactions dataset.
arachidonyl dopamine Gene Set From CTD Gene-Chemical Interactions genes/proteins interacting with the chemical arachidonyl dopamine from the curated CTD Gene-Chemical Interactions dataset.
dopamine beta hydroxylase deficiency Gene Set From CTD Gene-Disease Associations genes/proteins associated with the disease dopamine beta hydroxylase deficiency from the curated CTD Gene-Disease Associations dataset.
Dopamine Gene Set From DrugBank Drug Targets interacting proteins for the Dopamine drug from the curated DrugBank Drug Targets dataset.
reduced dopamine d2 receptor binding Gene Set From GAD Gene-Disease Associations genes associated with the disease reduced dopamine d2 receptor binding in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
dopamine d2 receptor density; monoamine metabolite concentrations Gene Set From GAD Gene-Disease Associations genes associated with the disease dopamine d2 receptor density; monoamine metabolite concentrations in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
dopamine beta-hydroxylase activity Gene Set From GAD Gene-Disease Associations genes associated with the disease dopamine beta-hydroxylase activity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
dopamine transporter availability Gene Set From GAD Gene-Disease Associations genes associated with the disease dopamine transporter availability in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
striatal dopamine transporter Gene Set From GAD Gene-Disease Associations genes associated with the disease striatal dopamine transporter in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
dopamine Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term dopamine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
dopamine uptake Gene Set From GO Biological Process Annotations 2015 genes participating in the dopamine uptake biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
dopamine biosynthetic process from tyrosine Gene Set From GO Biological Process Annotations 2015 genes participating in the dopamine biosynthetic process from tyrosine biological process from the curated GO Biological Process Annotations 2015 dataset.
dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2015 genes participating in the dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.
negative regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the negative regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.
dopamine catabolic process Gene Set From GO Biological Process Annotations 2015 genes participating in the dopamine catabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.
cellular response to dopamine Gene Set From GO Biological Process Annotations 2015 genes participating in the cellular response to dopamine biological process from the curated GO Biological Process Annotations 2015 dataset.
phospholipase c-activating dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the phospholipase c-activating dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2015 genes participating in the dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2015 dataset.
negative regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2015 genes participating in the negative regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.
dopamine transport Gene Set From GO Biological Process Annotations 2015 genes participating in the dopamine transport biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
adenylate cyclase-activating dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the adenylate cyclase-activating dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
negative regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2015 genes participating in the negative regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2015 dataset.
adenylate cyclase-inhibiting dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the adenylate cyclase-inhibiting dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
dopamine metabolic process Gene Set From GO Biological Process Annotations 2015 genes participating in the dopamine metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.
dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2015 genes participating in the dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.
negative regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2015 genes participating in the negative regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2015 dataset.
response to dopamine Gene Set From GO Biological Process Annotations 2015 genes participating in the response to dopamine biological process from the curated GO Biological Process Annotations 2015 dataset.
d2 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2015 genes performing the d2 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
d1 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2015 genes performing the d1 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine:sodium symporter activity Gene Set From GO Molecular Function Annotations 2015 genes performing the dopamine:sodium symporter activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine beta-monooxygenase activity Gene Set From GO Molecular Function Annotations 2015 genes performing the dopamine beta-monooxygenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine neurotransmitter receptor activity, coupled via gs Gene Set From GO Molecular Function Annotations 2015 genes performing the dopamine neurotransmitter receptor activity, coupled via gs molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine neurotransmitter receptor activity Gene Set From GO Molecular Function Annotations 2015 genes performing the dopamine neurotransmitter receptor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.
d3 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2015 genes performing the d3 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine transmembrane transporter activity Gene Set From GO Molecular Function Annotations 2015 genes performing the dopamine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine binding Gene Set From GO Molecular Function Annotations 2015 genes performing the dopamine binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
d5 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2015 genes performing the d5 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
d4 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2015 genes performing the d4 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine receptor binding Gene Set From GO Molecular Function Annotations 2015 genes performing the dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine neurotransmitter receptor activity, coupled via gi/go Gene Set From GO Molecular Function Annotations 2015 genes performing the dopamine neurotransmitter receptor activity, coupled via gi/go molecular function from the curated GO Molecular Function Annotations 2015 dataset.
dopamine Gene Set From Guide to Pharmacology Chemical Ligands of Receptors receptors of the dopamine ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.
Dopamine 3-O-sulfate Gene Set From HMDB Metabolites of Enzymes interacting proteins for the Dopamine 3-O-sulfate metabolite from the curated HMDB Metabolites of Enzymes dataset.
Dopamine Gene Set From HMDB Metabolites of Enzymes interacting proteins for the Dopamine metabolite from the curated HMDB Metabolites of Enzymes dataset.
Dopamine glucuronide Gene Set From HMDB Metabolites of Enzymes interacting proteins for the Dopamine glucuronide metabolite from the curated HMDB Metabolites of Enzymes dataset.
Dopamine 4-sulfate Gene Set From HMDB Metabolites of Enzymes interacting proteins for the Dopamine 4-sulfate metabolite from the curated HMDB Metabolites of Enzymes dataset.
elevated urinary dopamine Gene Set From HPO Gene-Disease Associations genes associated with the elevated urinary dopamine phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.
Dopamine receptor family Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Dopamine receptor family protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Dopamine D3 receptor Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Dopamine D3 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Sodium:neurotransmitter symporter, dopamine Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Sodium:neurotransmitter symporter, dopamine protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Dopamine/cAMP-regulated neuronal phosphoprotein Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Dopamine/cAMP-regulated neuronal phosphoprotein protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Tyramine beta-hydroxylase/Dopamine beta-hydroxylase Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Tyramine beta-hydroxylase/Dopamine beta-hydroxylase protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Dopamine beta-hydroxylase-related Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Dopamine beta-hydroxylase-related protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Dopamine D5 receptor Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Dopamine D5 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Dopamine D1 receptor Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Dopamine D1 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Dopamine D4 receptor Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Dopamine D4 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Dopamine D2 receptor Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Dopamine D2 receptor protein domain from the InterPro Predicted Protein Domain Annotations dataset.
decreased dopamine level Gene Set From MPO Gene-Phenotype Associations gene mutations causing the decreased dopamine level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
abnormal synaptic dopamine release Gene Set From MPO Gene-Phenotype Associations gene mutations causing the abnormal synaptic dopamine release phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
abnormal dopamine level Gene Set From MPO Gene-Phenotype Associations gene mutations causing the abnormal dopamine level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
increased dopamine level Gene Set From MPO Gene-Phenotype Associations gene mutations causing the increased dopamine level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
[dopamine-beta-hydroxylase activity levels, plasma] Gene Set From OMIM Gene-Disease Associations genes associated with the [dopamine-beta-hydroxylase activity levels, plasma] phenotype from the curated OMIM Gene-Disease Associations dataset.
dopamine beta-hydroxylase deficiency Gene Set From OMIM Gene-Disease Associations genes associated with the dopamine beta-hydroxylase deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.
dopamine receptor d2, reduced brain density of Gene Set From OMIM Gene-Disease Associations genes associated with the dopamine receptor d2, reduced brain density of phenotype from the curated OMIM Gene-Disease Associations dataset.
dopamine Gene Set From Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term dopamine in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.
Dopamine Neurotransmitter Release Cycle Gene Set From Reactome Pathways 2014 proteins participating in the Dopamine Neurotransmitter Release Cycle pathway from the Reactome Pathways dataset.
Dopamine receptors Gene Set From Reactome Pathways 2014 proteins participating in the Dopamine receptors pathway from the Reactome Pathways dataset.
Dopamine clearance from the synaptic cleft Gene Set From Reactome Pathways 2014 proteins participating in the Dopamine clearance from the synaptic cleft pathway from the Reactome Pathways dataset.
Dopamine metabolism(Homo sapiens) Gene Set From WikiPathways Pathways 2014 proteins participating in the Dopamine metabolism(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.
Dopamine Gene Set From DeepCoverMOA Drug Mechanisms of Action proteins with high or low expression in Dopamine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
Dopamine Beta Hydroxylase Deficiency Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Dopamine Beta Hydroxylase Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Brain Dopamine-Serotonin Vesicular Transport Disease Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Brain Dopamine-Serotonin Vesicular Transport Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Elevated Urinary Dopamine Gene Set From DisGeNET Gene-Phenotype Associations genes associated with the phenotype Elevated Urinary Dopamine in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.
Elevated Csf Dopamine Level Gene Set From DisGeNET Gene-Phenotype Associations genes associated with the phenotype Elevated Csf Dopamine Level in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.
dopamine secretion Gene Set From GO Biological Process Annotations 2023 genes participating in the dopamine secretion biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
dopamine transport Gene Set From GO Biological Process Annotations 2023 genes participating in the dopamine transport biological process from the curated GO Biological Process Annotations 2023 dataset.
dopamine uptake Gene Set From GO Biological Process Annotations 2023 genes participating in the dopamine uptake biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.
dopamine metabolic process Gene Set From GO Biological Process Annotations 2023 genes participating in the dopamine metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.
cellular response to dopamine Gene Set From GO Biological Process Annotations 2023 genes participating in the cellular response to dopamine biological process from the curated GO Biological Process Annotations 2023 dataset.
negative regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the negative regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.
negative regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2023 genes participating in the negative regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.
dopamine biosynthetic process from tyrosine Gene Set From GO Biological Process Annotations 2023 genes participating in the dopamine biosynthetic process from tyrosine biological process from the curated GO Biological Process Annotations 2023 dataset.
dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2023 genes participating in the dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.
dopamine catabolic process Gene Set From GO Biological Process Annotations 2023 genes participating in the dopamine catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.
phospholipase C-activating dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the phospholipase C-activating dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
adenylate cyclase-inhibiting dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the adenylate cyclase-inhibiting dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2023 dataset.
adenylate cyclase-activating dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the adenylate cyclase-activating dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2023 genes participating in the dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2023 dataset.
negative regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2023 genes participating in the negative regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
somato-dendritic dopamine secretion Gene Set From GO Biological Process Annotations 2023 genes participating in the somato-dendritic dopamine secretion biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.
negative regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2023 genes participating in the negative regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.
response to dopamine Gene Set From GO Biological Process Annotations 2023 genes participating in the response to dopamine biological process from the curated GO Biological Process Annotations 2023 dataset.
dopamine beta-monooxygenase activity Gene Set From GO Molecular Function Annotations 2023 genes performing the dopamine beta-monooxygenase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.
dopamine neurotransmitter receptor activity, coupled via Gi/Go Gene Set From GO Molecular Function Annotations 2023 genes performing the dopamine neurotransmitter receptor activity, coupled via Gi/Go molecular function from the curated GO Molecular Function Annotations 2023 dataset.
dopamine neurotransmitter receptor activity, coupled via Gs Gene Set From GO Molecular Function Annotations 2023 genes performing the dopamine neurotransmitter receptor activity, coupled via Gs molecular function from the curated GO Molecular Function Annotations 2023 dataset.
dopamine neurotransmitter receptor activity Gene Set From GO Molecular Function Annotations 2023 genes performing the dopamine neurotransmitter receptor activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.
dopamine binding Gene Set From GO Molecular Function Annotations 2023 genes performing the dopamine binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
dopamine:sodium symporter activity Gene Set From GO Molecular Function Annotations 2023 genes performing the dopamine:sodium symporter activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.
D1 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2023 genes performing the D1 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
D5 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2023 genes performing the D5 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
D4 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2023 genes performing the D4 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
D2 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2023 genes performing the D2 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
D3 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2023 genes performing the D3 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
dopamine receptor binding Gene Set From GO Molecular Function Annotations 2023 genes performing the dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.
increased dopamine level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the increased dopamine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
decreased dopamine level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased dopamine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
abnormal dopamine level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal dopamine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
abnormal synaptic dopamine release Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal synaptic dopamine release phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
increased urine dopamine level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the increased urine dopamine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
increased nervous system dopamine level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the increased nervous system dopamine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
abnormal nervous system dopamine level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal nervous system dopamine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
decreased nervous system dopamine level Gene Set From MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased nervous system dopamine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
Dopamine Gene Set From MW Enzyme Metabolite Associations interacting proteins for Dopamine metabolite from the MW Gene Metabolite Associations dataset.
Midbrain dopamine neuron_Brain_Mouse Gene Set From CellMarker Gene-Cell Type Associations genes associated with the Midbrain dopamine neuron_Brain_Mouse cell type from the CellMarker Gene-Cell Type Associations dataset.
Dopamine neuron_Nerve_Mouse Gene Set From CellMarker Gene-Cell Type Associations genes associated with the Dopamine neuron_Nerve_Mouse cell type from the CellMarker Gene-Cell Type Associations dataset.
Dopamine neuron_Skin_Human Gene Set From CellMarker Gene-Cell Type Associations genes associated with the Dopamine neuron_Skin_Human cell type from the CellMarker Gene-Cell Type Associations dataset.
Dopamine metabolism Gene Set From WikiPathways Pathways 2024 proteins participating in the Dopamine metabolism pathway from the WikiPathways Pathways 2024 dataset.
Dopamine Neurotransmitter Release Cycle Gene Set From Reactome Pathways 2024 proteins participating in the Dopamine Neurotransmitter Release Cycle pathway from the Reactome Pathways 2024 dataset.
Dopamine clearance from the synaptic cleft Gene Set From Reactome Pathways 2024 proteins participating in the Dopamine clearance from the synaptic cleft pathway from the Reactome Pathways 2024 dataset.
Dopamine receptors Gene Set From Reactome Pathways 2024 proteins participating in the Dopamine receptors pathway from the Reactome Pathways 2024 dataset.
dopamine secretion Gene Set From GO Biological Process Annotations 2025 genes participating in the dopamine secretion biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2025 dataset.
positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
G protein-coupled dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the G protein-coupled dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
dopamine transport Gene Set From GO Biological Process Annotations 2025 genes participating in the dopamine transport biological process from the curated GO Biological Process Annotations 2025 dataset.
dopamine uptake Gene Set From GO Biological Process Annotations 2025 genes participating in the dopamine uptake biological process from the curated GO Biological Process Annotations 2025 dataset.
adenylate cyclase-activating dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the adenylate cyclase-activating dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.
dopamine metabolic process Gene Set From GO Biological Process Annotations 2025 genes participating in the dopamine metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.
cellular response to dopamine Gene Set From GO Biological Process Annotations 2025 genes participating in the cellular response to dopamine biological process from the curated GO Biological Process Annotations 2025 dataset.
negative regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the negative regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
positive regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.
negative regulation of dopamine metabolic process Gene Set From GO Biological Process Annotations 2025 genes participating in the negative regulation of dopamine metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.
dopamine biosynthetic process from tyrosine Gene Set From GO Biological Process Annotations 2025 genes participating in the dopamine biosynthetic process from tyrosine biological process from the curated GO Biological Process Annotations 2025 dataset.
dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2025 genes participating in the dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.
dopamine catabolic process Gene Set From GO Biological Process Annotations 2025 genes participating in the dopamine catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.
phospholipase C-activating dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the phospholipase C-activating dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
adenylate cyclase-inhibiting dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the adenylate cyclase-inhibiting dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
positive regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2025 dataset.
positive regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2025 dataset.
positive regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2025 genes participating in the dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2025 dataset.
negative regulation of dopamine uptake involved in synaptic transmission Gene Set From GO Biological Process Annotations 2025 genes participating in the negative regulation of dopamine uptake involved in synaptic transmission biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
somato-dendritic dopamine secretion Gene Set From GO Biological Process Annotations 2025 genes participating in the somato-dendritic dopamine secretion biological process from the curated GO Biological Process Annotations 2025 dataset.
positive regulation of dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.
negative regulation of dopamine secretion Gene Set From GO Biological Process Annotations 2025 genes participating in the negative regulation of dopamine secretion biological process from the curated GO Biological Process Annotations 2025 dataset.
negative regulation of dopamine biosynthetic process Gene Set From GO Biological Process Annotations 2025 genes participating in the negative regulation of dopamine biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.
response to dopamine Gene Set From GO Biological Process Annotations 2025 genes participating in the response to dopamine biological process from the curated GO Biological Process Annotations 2025 dataset.
dopamine beta-monooxygenase activity Gene Set From GO Molecular Function Annotations 2025 genes performing the dopamine beta-monooxygenase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
dopamine neurotransmitter receptor activity, coupled via Gi/Go Gene Set From GO Molecular Function Annotations 2025 genes performing the dopamine neurotransmitter receptor activity, coupled via Gi/Go molecular function from the curated GO Molecular Function Annotations 2025 dataset.
dopamine neurotransmitter receptor activity, coupled via Gs Gene Set From GO Molecular Function Annotations 2025 genes performing the dopamine neurotransmitter receptor activity, coupled via Gs molecular function from the curated GO Molecular Function Annotations 2025 dataset.
dopamine neurotransmitter receptor activity Gene Set From GO Molecular Function Annotations 2025 genes performing the dopamine neurotransmitter receptor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
dopamine:sodium symporter activity Gene Set From GO Molecular Function Annotations 2025 genes performing the dopamine:sodium symporter activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
D1 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2025 genes performing the D1 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.
D2 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2025 genes performing the D2 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.
dopamine receptor binding Gene Set From GO Molecular Function Annotations 2025 genes performing the dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.
D5 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2025 genes performing the D5 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.
D4 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2025 genes performing the D4 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.
D3 dopamine receptor binding Gene Set From GO Molecular Function Annotations 2025 genes performing the D3 dopamine receptor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.
Dopamine beta-hydroxylase deficiency Gene Set From DISEASES Curated Gene-Disease Association Evidence Scores 2025 genes involed in the disease Dopamine beta-hydroxylase deficiency from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
Dopamine transporter deficiency syndrome Gene Set From DISEASES Curated Gene-Disease Association Evidence Scores 2025 genes involed in the disease Dopamine transporter deficiency syndrome from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.
Dopamine beta-hydroxylase deficiency Gene Set From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease Dopamine beta-hydroxylase deficiency in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
Dopamine transporter deficiency syndrome Gene Set From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease Dopamine transporter deficiency syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
Classic dopamine transporter deficiency syndrome Gene Set From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease Classic dopamine transporter deficiency syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
Atypical dopamine transporter deficiency syndrome Gene Set From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 genes co-occuring with the disease Atypical dopamine transporter deficiency syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.
Classic dopamine transporter deficiency syndrome Gene Set From ClinVar Gene-Phenotype Associations 2025 genes associated with the Classic dopamine transporter deficiency syndrome phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
Brain dopamine-serotonin vesicular transport disease Gene Set From ClinVar Gene-Phenotype Associations 2025 genes associated with the Brain dopamine-serotonin vesicular transport disease phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.
DOPAMINE Gene Set From DGIdb Drug Targets 2026 interacting proteins for the DOPAMINE drug from theDGIdb Drug Targets 2026 dataset.
DOPAMINE HYDROCHLORIDE Gene Set From DGIdb Drug Targets 2026 interacting proteins for the DOPAMINE HYDROCHLORIDE drug from theDGIdb Drug Targets 2026 dataset.
CEREBRAL DOPAMINE NEUROTROPHIC FACTOR Gene Set From DGIdb Drug Targets 2026 interacting proteins for the CEREBRAL DOPAMINE NEUROTROPHIC FACTOR drug from theDGIdb Drug Targets 2026 dataset.
er associated degradation (erad) pathway Gene Set From Biocarta Pathways proteins participating in the er associated degradation (erad) pathway pathway from the Biocarta Pathways dataset.
degradation of the rar and rxr by the proteasome Gene Set From Biocarta Pathways proteins participating in the degradation of the rar and rxr by the proteasome pathway from the Biocarta Pathways dataset.
dna degradation, necrotic Gene Set From GAD Gene-Disease Associations genes associated with the disease dna degradation, necrotic in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
degradation Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term degradation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation Gene Set From GO Biological Process Annotations 2015 genes participating in the negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation biological process from the curated GO Biological Process Annotations 2015 dataset.
mitochondrion degradation by induced vacuole formation Gene Set From GO Biological Process Annotations 2015 genes participating in the mitochondrion degradation by induced vacuole formation biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of mitochondrion degradation Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of mitochondrion degradation Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.
mitochondrion degradation Gene Set From GO Biological Process Annotations 2015 genes participating in the mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.
negative regulation of mitochondrion degradation Gene Set From GO Biological Process Annotations 2015 genes participating in the negative regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.
peroxisome degradation Gene Set From GO Biological Process Annotations 2015 genes participating in the peroxisome degradation biological process from the curated GO Biological Process Annotations 2015 dataset.
DNA Degradation, Necrotic Gene Set From HuGE Navigator Gene-Phenotype Associations genes associated with the DNA Degradation, Necrotic phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.
α-tocopherol degradation Gene Set From HumanCyc Pathways proteins participating in the α-tocopherol degradation pathway from the HumanCyc Pathways dataset.
sorbitol degradation I Gene Set From HumanCyc Pathways proteins participating in the sorbitol degradation I pathway from the HumanCyc Pathways dataset.
methylglyoxal degradation III Gene Set From HumanCyc Pathways proteins participating in the methylglyoxal degradation III pathway from the HumanCyc Pathways dataset.
tryptophan degradation Gene Set From HumanCyc Pathways proteins participating in the tryptophan degradation pathway from the HumanCyc Pathways dataset.
methylglyoxal degradation VI Gene Set From HumanCyc Pathways proteins participating in the methylglyoxal degradation VI pathway from the HumanCyc Pathways dataset.
melatonin degradation II Gene Set From HumanCyc Pathways proteins participating in the melatonin degradation II pathway from the HumanCyc Pathways dataset.
L-serine degradation Gene Set From HumanCyc Pathways proteins participating in the L-serine degradation pathway from the HumanCyc Pathways dataset.
alanine biosynthesis/degradation Gene Set From HumanCyc Pathways proteins participating in the alanine biosynthesis/degradation pathway from the HumanCyc Pathways dataset.
N-acetylglucosamine degradation I Gene Set From HumanCyc Pathways proteins participating in the N-acetylglucosamine degradation I pathway from the HumanCyc Pathways dataset.
glutaryl-CoA degradation Gene Set From HumanCyc Pathways proteins participating in the glutaryl-CoA degradation pathway from the HumanCyc Pathways dataset.
asparagine degradation Gene Set From HumanCyc Pathways proteins participating in the asparagine degradation pathway from the HumanCyc Pathways dataset.
ethanol degradation IV Gene Set From HumanCyc Pathways proteins participating in the ethanol degradation IV pathway from the HumanCyc Pathways dataset.
tyrosine degradation Gene Set From HumanCyc Pathways proteins participating in the tyrosine degradation pathway from the HumanCyc Pathways dataset.
glutamate biosynthesis/degradation Gene Set From HumanCyc Pathways proteins participating in the glutamate biosynthesis/degradation pathway from the HumanCyc Pathways dataset.
superoxide radicals degradation Gene Set From HumanCyc Pathways proteins participating in the superoxide radicals degradation pathway from the HumanCyc Pathways dataset.
phenylethylamine degradation I Gene Set From HumanCyc Pathways proteins participating in the phenylethylamine degradation I pathway from the HumanCyc Pathways dataset.
putrescine degradation III Gene Set From HumanCyc Pathways proteins participating in the putrescine degradation III pathway from the HumanCyc Pathways dataset.
S-methyl-5-thio-α-D-ribose 1-phosphate degradation Gene Set From HumanCyc Pathways proteins participating in the S-methyl-5-thio-α-D-ribose 1-phosphate degradation pathway from the HumanCyc Pathways dataset.
3-phosphoinositide degradation Gene Set From HumanCyc Pathways proteins participating in the 3-phosphoinositide degradation pathway from the HumanCyc Pathways dataset.
methionine degradation Gene Set From HumanCyc Pathways proteins participating in the methionine degradation pathway from the HumanCyc Pathways dataset.
trehalose degradation Gene Set From HumanCyc Pathways proteins participating in the trehalose degradation pathway from the HumanCyc Pathways dataset.
thyroid hormone metabolism II (via conjugation and/or degradation) Gene Set From HumanCyc Pathways proteins participating in the thyroid hormone metabolism II (via conjugation and/or degradation) pathway from the HumanCyc Pathways dataset.
S-methyl-5'-thioadenosine degradation Gene Set From HumanCyc Pathways proteins participating in the S-methyl-5'-thioadenosine degradation pathway from the HumanCyc Pathways dataset.
tryptophan degradation X (mammalian, via tryptamine) Gene Set From HumanCyc Pathways proteins participating in the tryptophan degradation X (mammalian, via tryptamine) pathway from the HumanCyc Pathways dataset.
lactose degradation III Gene Set From HumanCyc Pathways proteins participating in the lactose degradation III pathway from the HumanCyc Pathways dataset.
phenylalanine degradation/tyrosine biosynthesis Gene Set From HumanCyc Pathways proteins participating in the phenylalanine degradation/tyrosine biosynthesis pathway from the HumanCyc Pathways dataset.
L-cysteine degradation II Gene Set From HumanCyc Pathways proteins participating in the L-cysteine degradation II pathway from the HumanCyc Pathways dataset.
tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde Gene Set From HumanCyc Pathways proteins participating in the tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde pathway from the HumanCyc Pathways dataset.
ethanol degradation II Gene Set From HumanCyc Pathways proteins participating in the ethanol degradation II pathway from the HumanCyc Pathways dataset.
uracil degradation Gene Set From HumanCyc Pathways proteins participating in the uracil degradation pathway from the HumanCyc Pathways dataset.
L-kynurenine degradation Gene Set From HumanCyc Pathways proteins participating in the L-kynurenine degradation pathway from the HumanCyc Pathways dataset.
threonine degradation Gene Set From HumanCyc Pathways proteins participating in the threonine degradation pathway from the HumanCyc Pathways dataset.
D-myo-inositol (1,4,5)-trisphosphate degradation Gene Set From HumanCyc Pathways proteins participating in the D-myo-inositol (1,4,5)-trisphosphate degradation pathway from the HumanCyc Pathways dataset.
cysteine biosynthesis/homocysteine degradation (trans-sulfuration) Gene Set From HumanCyc Pathways proteins participating in the cysteine biosynthesis/homocysteine degradation (trans-sulfuration) pathway from the HumanCyc Pathways dataset.
superpathway of choline degradation to L-serine Gene Set From HumanCyc Pathways proteins participating in the superpathway of choline degradation to L-serine pathway from the HumanCyc Pathways dataset.
serotonin degradation Gene Set From HumanCyc Pathways proteins participating in the serotonin degradation pathway from the HumanCyc Pathways dataset.
methylglyoxal degradation I Gene Set From HumanCyc Pathways proteins participating in the methylglyoxal degradation I pathway from the HumanCyc Pathways dataset.
dermatan sulfate degradation (metazoa) Gene Set From HumanCyc Pathways proteins participating in the dermatan sulfate degradation (metazoa) pathway from the HumanCyc Pathways dataset.
guanosine nucleotides degradation Gene Set From HumanCyc Pathways proteins participating in the guanosine nucleotides degradation pathway from the HumanCyc Pathways dataset.
pyrimidine deoxyribonucleosides degradation Gene Set From HumanCyc Pathways proteins participating in the pyrimidine deoxyribonucleosides degradation pathway from the HumanCyc Pathways dataset.
lysine degradation II (pipecolate pathway) Gene Set From HumanCyc Pathways proteins participating in the lysine degradation II (pipecolate pathway) pathway from the HumanCyc Pathways dataset.
L-dopa degradation Gene Set From HumanCyc Pathways proteins participating in the L-dopa degradation pathway from the HumanCyc Pathways dataset.
histamine degradation Gene Set From HumanCyc Pathways proteins participating in the histamine degradation pathway from the HumanCyc Pathways dataset.
2'-deoxy-α-D-ribose 1-phosphate degradation Gene Set From HumanCyc Pathways proteins participating in the 2'-deoxy-α-D-ribose 1-phosphate degradation pathway from the HumanCyc Pathways dataset.
pyrimidine ribonucleosides degradation Gene Set From HumanCyc Pathways proteins participating in the pyrimidine ribonucleosides degradation pathway from the HumanCyc Pathways dataset.
D-mannose degradation Gene Set From HumanCyc Pathways proteins participating in the D-mannose degradation pathway from the HumanCyc Pathways dataset.
purine nucleotides degradation Gene Set From HumanCyc Pathways proteins participating in the purine nucleotides degradation pathway from the HumanCyc Pathways dataset.
noradrenaline and adrenaline degradation Gene Set From HumanCyc Pathways proteins participating in the noradrenaline and adrenaline degradation pathway from the HumanCyc Pathways dataset.
2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA Gene Set From HumanCyc Pathways proteins participating in the 2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA pathway from the HumanCyc Pathways dataset.
superpathway of methionine degradation Gene Set From HumanCyc Pathways proteins participating in the superpathway of methionine degradation pathway from the HumanCyc Pathways dataset.
4-aminobutyrate degradation Gene Set From HumanCyc Pathways proteins participating in the 4-aminobutyrate degradation pathway from the HumanCyc Pathways dataset.
anandamide degradation Gene Set From HumanCyc Pathways proteins participating in the anandamide degradation pathway from the HumanCyc Pathways dataset.
glycine betaine degradation Gene Set From HumanCyc Pathways proteins participating in the glycine betaine degradation pathway from the HumanCyc Pathways dataset.
spermine and spermidine degradation I Gene Set From HumanCyc Pathways proteins participating in the spermine and spermidine degradation I pathway from the HumanCyc Pathways dataset.
glycerol degradation Gene Set From HumanCyc Pathways proteins participating in the glycerol degradation pathway from the HumanCyc Pathways dataset.
phytol degradation Gene Set From HumanCyc Pathways proteins participating in the phytol degradation pathway from the HumanCyc Pathways dataset.
L-cysteine degradation I Gene Set From HumanCyc Pathways proteins participating in the L-cysteine degradation I pathway from the HumanCyc Pathways dataset.
histidine degradation Gene Set From HumanCyc Pathways proteins participating in the histidine degradation pathway from the HumanCyc Pathways dataset.
β-alanine degradation Gene Set From HumanCyc Pathways proteins participating in the β-alanine degradation pathway from the HumanCyc Pathways dataset.
sucrose degradation Gene Set From HumanCyc Pathways proteins participating in the sucrose degradation pathway from the HumanCyc Pathways dataset.
D-galactose degradation V (Leloir pathway) Gene Set From HumanCyc Pathways proteins participating in the D-galactose degradation V (Leloir pathway) pathway from the HumanCyc Pathways dataset.
urate biosynthesis/inosine 5'-phosphate degradation Gene Set From HumanCyc Pathways proteins participating in the urate biosynthesis/inosine 5'-phosphate degradation pathway from the HumanCyc Pathways dataset.
glutamine degradation/glutamate biosynthesis Gene Set From HumanCyc Pathways proteins participating in the glutamine degradation/glutamate biosynthesis pathway from the HumanCyc Pathways dataset.
purine deoxyribonucleosides degradation Gene Set From HumanCyc Pathways proteins participating in the purine deoxyribonucleosides degradation pathway from the HumanCyc Pathways dataset.
lysine degradation I (saccharopine pathway) Gene Set From HumanCyc Pathways proteins participating in the lysine degradation I (saccharopine pathway) pathway from the HumanCyc Pathways dataset.
oxidative ethanol degradation III Gene Set From HumanCyc Pathways proteins participating in the oxidative ethanol degradation III pathway from the HumanCyc Pathways dataset.
4-hydroxyproline degradation Gene Set From HumanCyc Pathways proteins participating in the 4-hydroxyproline degradation pathway from the HumanCyc Pathways dataset.
triacylglycerol degradation Gene Set From HumanCyc Pathways proteins participating in the triacylglycerol degradation pathway from the HumanCyc Pathways dataset.
purine ribonucleosides degradation to ribose-1-phosphate Gene Set From HumanCyc Pathways proteins participating in the purine ribonucleosides degradation to ribose-1-phosphate pathway from the HumanCyc Pathways dataset.
heme degradation Gene Set From HumanCyc Pathways proteins participating in the heme degradation pathway from the HumanCyc Pathways dataset.
propionyl-CoA degradation Gene Set From HumanCyc Pathways proteins participating in the propionyl-CoA degradation pathway from the HumanCyc Pathways dataset.
proline degradation Gene Set From HumanCyc Pathways proteins participating in the proline degradation pathway from the HumanCyc Pathways dataset.
2-oxobutanoate degradation Gene Set From HumanCyc Pathways proteins participating in the 2-oxobutanoate degradation pathway from the HumanCyc Pathways dataset.
chondroitin sulfate degradation (metazoa) Gene Set From HumanCyc Pathways proteins participating in the chondroitin sulfate degradation (metazoa) pathway from the HumanCyc Pathways dataset.
D-glucuronate degradation Gene Set From HumanCyc Pathways proteins participating in the D-glucuronate degradation pathway from the HumanCyc Pathways dataset.
N-acetylglucosamine degradation II Gene Set From HumanCyc Pathways proteins participating in the N-acetylglucosamine degradation II pathway from the HumanCyc Pathways dataset.
adenosine nucleotides degradation Gene Set From HumanCyc Pathways proteins participating in the adenosine nucleotides degradation pathway from the HumanCyc Pathways dataset.
thymine degradation Gene Set From HumanCyc Pathways proteins participating in the thymine degradation pathway from the HumanCyc Pathways dataset.
choline degradation Gene Set From HumanCyc Pathways proteins participating in the choline degradation pathway from the HumanCyc Pathways dataset.
Phenylacetic acid degradation-related domain Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Phenylacetic acid degradation-related domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Ubiquitin fusion degradation protein UFD1 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Ubiquitin fusion degradation protein UFD1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Vacuolar import/degradation protein Vid24 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Vacuolar import/degradation protein Vid24 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
atrazine degradation Gene Set From KEGG Pathways proteins participating in the atrazine degradation pathway from the KEGG Pathways dataset.
3 chloroacrylic acid degradation Gene Set From KEGG Pathways proteins participating in the 3 chloroacrylic acid degradation pathway from the KEGG Pathways dataset.
1 and 2 methylnaphthalene degradation Gene Set From KEGG Pathways proteins participating in the 1 and 2 methylnaphthalene degradation pathway from the KEGG Pathways dataset.
naphthalene and anthracene degradation Gene Set From KEGG Pathways proteins participating in the naphthalene and anthracene degradation pathway from the KEGG Pathways dataset.
caprolactam degradation Gene Set From KEGG Pathways proteins participating in the caprolactam degradation pathway from the KEGG Pathways dataset.
ethylbenzene degradation Gene Set From KEGG Pathways proteins participating in the ethylbenzene degradation pathway from the KEGG Pathways dataset.
gamma hexachlorocyclohexane degradation Gene Set From KEGG Pathways proteins participating in the gamma hexachlorocyclohexane degradation pathway from the KEGG Pathways dataset.
limonene and pinene degradation Gene Set From KEGG Pathways proteins participating in the limonene and pinene degradation pathway from the KEGG Pathways dataset.
bisphenol a degradation Gene Set From KEGG Pathways proteins participating in the bisphenol a degradation pathway from the KEGG Pathways dataset.
1,4 dichlorobenzene degradation Gene Set From KEGG Pathways proteins participating in the 1,4 dichlorobenzene degradation pathway from the KEGG Pathways dataset.
benzoate degradation via coa ligation Gene Set From KEGG Pathways proteins participating in the benzoate degradation via coa ligation pathway from the KEGG Pathways dataset.
tetrachloroethene degradation Gene Set From KEGG Pathways proteins participating in the tetrachloroethene degradation pathway from the KEGG Pathways dataset.
n glycan degradation Gene Set From KEGG Pathways proteins participating in the n glycan degradation pathway from the KEGG Pathways dataset.
synthesis and degradation of ketone bodies Gene Set From KEGG Pathways proteins participating in the synthesis and degradation of ketone bodies pathway from the KEGG Pathways dataset.
styrene degradation Gene Set From KEGG Pathways proteins participating in the styrene degradation pathway from the KEGG Pathways dataset.
valine leucine and isoleucine degradation Gene Set From KEGG Pathways proteins participating in the valine leucine and isoleucine degradation pathway from the KEGG Pathways dataset.
lysine degradation Gene Set From KEGG Pathways proteins participating in the lysine degradation pathway from the KEGG Pathways dataset.
glycosaminoglycan degradation Gene Set From KEGG Pathways proteins participating in the glycosaminoglycan degradation pathway from the KEGG Pathways dataset.
glycan structures degradation Gene Set From KEGG Pathways proteins participating in the glycan structures degradation pathway from the KEGG Pathways dataset.
Ornithine degradation Gene Set From PANTHER Pathways proteins participating in the Ornithine degradation pathway from the PANTHER Pathways dataset.
Ascorbate degradation Gene Set From PANTHER Pathways proteins participating in the Ascorbate degradation pathway from the PANTHER Pathways dataset.
Phenylethylamine degradation Gene Set From PANTHER Pathways proteins participating in the Phenylethylamine degradation pathway from the PANTHER Pathways dataset.
Allantoin degradation Gene Set From PANTHER Pathways proteins participating in the Allantoin degradation pathway from the PANTHER Pathways dataset.
Aminobutyrate degradation Gene Set From PANTHER Pathways proteins participating in the Aminobutyrate degradation pathway from the PANTHER Pathways dataset.
degradation Gene Set From Phosphosite Textmining Biological Term Annotations proteins co-occuring with the biological term degradation in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.
Degradation of beta catenin Gene Set From PID Pathways proteins participating in the Degradation of beta catenin pathway from the PID Pathways dataset.
SCF-beta-TrCP mediated degradation of Emi1 Gene Set From Reactome Pathways 2014 proteins participating in the SCF-beta-TrCP mediated degradation of Emi1 pathway from the Reactome Pathways dataset.
Degradation of GABA Gene Set From Reactome Pathways 2014 proteins participating in the Degradation of GABA pathway from the Reactome Pathways dataset.
HS-GAG degradation Gene Set From Reactome Pathways 2014 proteins participating in the HS-GAG degradation pathway from the Reactome Pathways dataset.
Gap junction degradation Gene Set From Reactome Pathways 2014 proteins participating in the Gap junction degradation pathway from the Reactome Pathways dataset.
Ubiquitin-dependent degradation of Cyclin D1 Gene Set From Reactome Pathways 2014 proteins participating in the Ubiquitin-dependent degradation of Cyclin D1 pathway from the Reactome Pathways dataset.
Hyaluronan uptake and degradation Gene Set From Reactome Pathways 2014 proteins participating in the Hyaluronan uptake and degradation pathway from the Reactome Pathways dataset.
Biosynthesis of A2E, implicated in retinal degradation Gene Set From Reactome Pathways 2014 proteins participating in the Biosynthesis of A2E, implicated in retinal degradation pathway from the Reactome Pathways dataset.
APC/C:Cdc20 mediated degradation of mitotic proteins Gene Set From Reactome Pathways 2014 proteins participating in the APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways dataset.
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint Gene Set From Reactome Pathways 2014 proteins participating in the APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint pathway from the Reactome Pathways dataset.
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Gene Set From Reactome Pathways 2014 proteins participating in the Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways dataset.
APC-Cdc20 mediated degradation of Nek2A Gene Set From Reactome Pathways 2014 proteins participating in the APC-Cdc20 mediated degradation of Nek2A pathway from the Reactome Pathways dataset.
degradation of DVL Gene Set From Reactome Pathways 2014 proteins participating in the degradation of DVL pathway from the Reactome Pathways dataset.
Keratan sulfate degradation Gene Set From Reactome Pathways 2014 proteins participating in the Keratan sulfate degradation pathway from the Reactome Pathways dataset.
degradation of AXIN Gene Set From Reactome Pathways 2014 proteins participating in the degradation of AXIN pathway from the Reactome Pathways dataset.
Degradation of GLI2 by the proteasome Gene Set From Reactome Pathways 2014 proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways dataset.
CS/DS degradation Gene Set From Reactome Pathways 2014 proteins participating in the CS/DS degradation pathway from the Reactome Pathways dataset.
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Gene Set From Reactome Pathways 2014 proteins participating in the APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway from the Reactome Pathways dataset.
Regulation of activated PAK-2p34 by proteasome mediated degradation Gene Set From Reactome Pathways 2014 proteins participating in the Regulation of activated PAK-2p34 by proteasome mediated degradation pathway from the Reactome Pathways dataset.
Degradation of cysteine and homocysteine Gene Set From Reactome Pathways 2014 proteins participating in the Degradation of cysteine and homocysteine pathway from the Reactome Pathways dataset.
Collagen degradation Gene Set From Reactome Pathways 2014 proteins participating in the Collagen degradation pathway from the Reactome Pathways dataset.
GABA synthesis, release, reuptake and degradation Gene Set From Reactome Pathways 2014 proteins participating in the GABA synthesis, release, reuptake and degradation pathway from the Reactome Pathways dataset.
APC/C:Cdc20 mediated degradation of Securin Gene Set From Reactome Pathways 2014 proteins participating in the APC/C:Cdc20 mediated degradation of Securin pathway from the Reactome Pathways dataset.
APC/C:Cdc20 mediated degradation of Cyclin B Gene Set From Reactome Pathways 2014 proteins participating in the APC/C:Cdc20 mediated degradation of Cyclin B pathway from the Reactome Pathways dataset.
SCF(Skp2)-mediated degradation of p27/p21 Gene Set From Reactome Pathways 2014 proteins participating in the SCF(Skp2)-mediated degradation of p27/p21 pathway from the Reactome Pathways dataset.
Ubiquitin-dependent degradation of Cyclin D Gene Set From Reactome Pathways 2014 proteins participating in the Ubiquitin-dependent degradation of Cyclin D pathway from the Reactome Pathways dataset.
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Gene Set From Reactome Pathways 2014 proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways dataset.
Vif-mediated degradation of APOBEC3G Gene Set From Reactome Pathways 2014 proteins participating in the Vif-mediated degradation of APOBEC3G pathway from the Reactome Pathways dataset.
APC/C-mediated degradation of cell cycle proteins Gene Set From Reactome Pathways 2014 proteins participating in the APC/C-mediated degradation of cell cycle proteins pathway from the Reactome Pathways dataset.
Degradation of the extracellular matrix Gene Set From Reactome Pathways 2014 proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways dataset.
Vpu mediated degradation of CD4 Gene Set From Reactome Pathways 2014 proteins participating in the Vpu mediated degradation of CD4 pathway from the Reactome Pathways dataset.
Cdc20:Phospho-APC/C mediated degradation of Cyclin A Gene Set From Reactome Pathways 2014 proteins participating in the Cdc20:Phospho-APC/C mediated degradation of Cyclin A pathway from the Reactome Pathways dataset.
Antigen processing: Ubiquitination & Proteasome degradation Gene Set From Reactome Pathways 2014 proteins participating in the Antigen processing: Ubiquitination & Proteasome degradation pathway from the Reactome Pathways dataset.
Heme degradation Gene Set From Reactome Pathways 2014 proteins participating in the Heme degradation pathway from the Reactome Pathways dataset.
Degradation of GLI1 by the proteasome Gene Set From Reactome Pathways 2014 proteins participating in the Degradation of GLI1 by the proteasome pathway from the Reactome Pathways dataset.
Degradation of beta-catenin by the destruction complex Gene Set From Reactome Pathways 2014 proteins participating in the Degradation of beta-catenin by the destruction complex pathway from the Reactome Pathways dataset.
Synthesis and Degradation of Ketone Bodies(Mus musculus) Gene Set From WikiPathways Pathways 2014 proteins participating in the Synthesis and Degradation of Ketone Bodies(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.
Proteasome Degradation(Homo sapiens) Gene Set From WikiPathways Pathways 2014 proteins participating in the Proteasome Degradation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.
Proteasome Degradation(Mus musculus) Gene Set From WikiPathways Pathways 2014 proteins participating in the Proteasome Degradation(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.
Synthesis and Degradation of Ketone Bodies(Homo sapiens) Gene Set From WikiPathways Pathways 2014 proteins participating in the Synthesis and Degradation of Ketone Bodies(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.
PCSK9-mediated LDLR degradation(Homo sapiens) Gene Set From WikiPathways Pathways 2014 proteins participating in the PCSK9-mediated LDLR degradation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.
target-directed miRNA degradation Gene Set From GO Biological Process Annotations 2023 genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2023 dataset.
Proteasome degradation Gene Set From WikiPathways Pathways 2024 proteins participating in the Proteasome degradation pathway from the WikiPathways Pathways 2024 dataset.
PCSK9 mediated LDL receptor degradation Gene Set From WikiPathways Pathways 2024 proteins participating in the PCSK9 mediated LDL receptor degradation pathway from the WikiPathways Pathways 2024 dataset.
Degradation pathway of sphingolipids including diseases Gene Set From WikiPathways Pathways 2024 proteins participating in the Degradation pathway of sphingolipids including diseases pathway from the WikiPathways Pathways 2024 dataset.
Gamma glutamyl cycle for the biosynthesis and degradation of glutathione including diseases Gene Set From WikiPathways Pathways 2024 proteins participating in the Gamma glutamyl cycle for the biosynthesis and degradation of glutathione including diseases pathway from the WikiPathways Pathways 2024 dataset.
Glycosaminoglycan degradation Gene Set From WikiPathways Pathways 2024 proteins participating in the Glycosaminoglycan degradation pathway from the WikiPathways Pathways 2024 dataset.
Glycogen synthesis and degradation Gene Set From WikiPathways Pathways 2024 proteins participating in the Glycogen synthesis and degradation pathway from the WikiPathways Pathways 2024 dataset.
APC-Cdc20 mediated degradation of Nek2A Gene Set From Reactome Pathways 2024 proteins participating in the APC-Cdc20 mediated degradation of Nek2A pathway from the Reactome Pathways 2024 dataset.
APC/C-mediated degradation of cell cycle proteins Gene Set From Reactome Pathways 2024 proteins participating in the APC/C-mediated degradation of cell cycle proteins pathway from the Reactome Pathways 2024 dataset.
APC/C:Cdc20 mediated degradation of Cyclin B Gene Set From Reactome Pathways 2024 proteins participating in the APC/C:Cdc20 mediated degradation of Cyclin B pathway from the Reactome Pathways 2024 dataset.
APC/C:Cdc20 mediated degradation of Securin Gene Set From Reactome Pathways 2024 proteins participating in the APC/C:Cdc20 mediated degradation of Securin pathway from the Reactome Pathways 2024 dataset.
APC/C:Cdc20 mediated degradation of mitotic proteins Gene Set From Reactome Pathways 2024 proteins participating in the APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways 2024 dataset.
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Gene Set From Reactome Pathways 2024 proteins participating in the APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway from the Reactome Pathways 2024 dataset.
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint Gene Set From Reactome Pathways 2024 proteins participating in the APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint pathway from the Reactome Pathways 2024 dataset.
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Gene Set From Reactome Pathways 2024 proteins participating in the Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways 2024 dataset.
Antigen processing: Ubiquitination & Proteasome degradation Gene Set From Reactome Pathways 2024 proteins participating in the Antigen processing: Ubiquitination & Proteasome degradation pathway from the Reactome Pathways 2024 dataset.
Biosynthesis of A2E, implicated in retinal degradation Gene Set From Reactome Pathways 2024 proteins participating in the Biosynthesis of A2E, implicated in retinal degradation pathway from the Reactome Pathways 2024 dataset.
CS/DS degradation Gene Set From Reactome Pathways 2024 proteins participating in the CS/DS degradation pathway from the Reactome Pathways 2024 dataset.
Cdc20:Phospho-APC/C mediated degradation of Cyclin A Gene Set From Reactome Pathways 2024 proteins participating in the Cdc20:Phospho-APC/C mediated degradation of Cyclin A pathway from the Reactome Pathways 2024 dataset.
Collagen degradation Gene Set From Reactome Pathways 2024 proteins participating in the Collagen degradation pathway from the Reactome Pathways 2024 dataset.
Degradation of AXIN Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of AXIN pathway from the Reactome Pathways 2024 dataset.
Degradation of DVL Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of DVL pathway from the Reactome Pathways 2024 dataset.
Degradation of GABA Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of GABA pathway from the Reactome Pathways 2024 dataset.
Degradation of GLI1 by the proteasome Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of GLI1 by the proteasome pathway from the Reactome Pathways 2024 dataset.
Degradation of GLI2 by the proteasome Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways 2024 dataset.
Degradation of beta-catenin by the destruction complex Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of beta-catenin by the destruction complex pathway from the Reactome Pathways 2024 dataset.
Degradation of cysteine and homocysteine Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of cysteine and homocysteine pathway from the Reactome Pathways 2024 dataset.
Degradation of the extracellular matrix Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways 2024 dataset.
GABA synthesis, release, reuptake and degradation Gene Set From Reactome Pathways 2024 proteins participating in the GABA synthesis, release, reuptake and degradation pathway from the Reactome Pathways 2024 dataset.
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 Gene Set From Reactome Pathways 2024 proteins participating in the GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 pathway from the Reactome Pathways 2024 dataset.
Gap junction degradation Gene Set From Reactome Pathways 2024 proteins participating in the Gap junction degradation pathway from the Reactome Pathways 2024 dataset.
Glycine degradation Gene Set From Reactome Pathways 2024 proteins participating in the Glycine degradation pathway from the Reactome Pathways 2024 dataset.
Glyoxylate metabolism and glycine degradation Gene Set From Reactome Pathways 2024 proteins participating in the Glyoxylate metabolism and glycine degradation pathway from the Reactome Pathways 2024 dataset.
HS-GAG degradation Gene Set From Reactome Pathways 2024 proteins participating in the HS-GAG degradation pathway from the Reactome Pathways 2024 dataset.
Heme degradation Gene Set From Reactome Pathways 2024 proteins participating in the Heme degradation pathway from the Reactome Pathways 2024 dataset.
Hyaluronan uptake and degradation Gene Set From Reactome Pathways 2024 proteins participating in the Hyaluronan uptake and degradation pathway from the Reactome Pathways 2024 dataset.
Keratan sulfate degradation Gene Set From Reactome Pathways 2024 proteins participating in the Keratan sulfate degradation pathway from the Reactome Pathways 2024 dataset.
M-decay: degradation of maternal mRNAs by maternally stored factors Gene Set From Reactome Pathways 2024 proteins participating in the M-decay: degradation of maternal mRNAs by maternally stored factors pathway from the Reactome Pathways 2024 dataset.
Mitochondrial RNA degradation Gene Set From Reactome Pathways 2024 proteins participating in the Mitochondrial RNA degradation pathway from the Reactome Pathways 2024 dataset.
Mitochondrial protein degradation Gene Set From Reactome Pathways 2024 proteins participating in the Mitochondrial protein degradation pathway from the Reactome Pathways 2024 dataset.
Regulation of TP53 Degradation Gene Set From Reactome Pathways 2024 proteins participating in the Regulation of TP53 Degradation pathway from the Reactome Pathways 2024 dataset.
Regulation of TP53 Expression and Degradation Gene Set From Reactome Pathways 2024 proteins participating in the Regulation of TP53 Expression and Degradation pathway from the Reactome Pathways 2024 dataset.
Regulation of activated PAK-2p34 by proteasome mediated degradation Gene Set From Reactome Pathways 2024 proteins participating in the Regulation of activated PAK-2p34 by proteasome mediated degradation pathway from the Reactome Pathways 2024 dataset.
SCF(Skp2)-mediated degradation of p27/p21 Gene Set From Reactome Pathways 2024 proteins participating in the SCF(Skp2)-mediated degradation of p27/p21 pathway from the Reactome Pathways 2024 dataset.
SCF-beta-TrCP mediated degradation of Emi1 Gene Set From Reactome Pathways 2024 proteins participating in the SCF-beta-TrCP mediated degradation of Emi1 pathway from the Reactome Pathways 2024 dataset.
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Gene Set From Reactome Pathways 2024 proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways 2024 dataset.
Ubiquitin-dependent degradation of Cyclin D Gene Set From Reactome Pathways 2024 proteins participating in the Ubiquitin-dependent degradation of Cyclin D pathway from the Reactome Pathways 2024 dataset.
VLDLR internalisation and degradation Gene Set From Reactome Pathways 2024 proteins participating in the VLDLR internalisation and degradation pathway from the Reactome Pathways 2024 dataset.
Vif-mediated degradation of APOBEC3G Gene Set From Reactome Pathways 2024 proteins participating in the Vif-mediated degradation of APOBEC3G pathway from the Reactome Pathways 2024 dataset.
Vpu mediated degradation of CD4 Gene Set From Reactome Pathways 2024 proteins participating in the Vpu mediated degradation of CD4 pathway from the Reactome Pathways 2024 dataset.
Z-decay: degradation of maternal mRNAs by zygotically expressed factors Gene Set From Reactome Pathways 2024 proteins participating in the Z-decay: degradation of maternal mRNAs by zygotically expressed factors pathway from the Reactome Pathways 2024 dataset.
target-directed miRNA degradation Gene Set From GO Biological Process Annotations 2025 genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2025 dataset.
Ethanolamine degradation polyhedral organelle Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Ethanolamine degradation polyhedral organelle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
Fatty acid degradation Gene Set From KEGG Pathways 2026 proteins participating in the Fatty acid degradation pathway from the KEGG Pathways 2026 dataset.
Valine, leucine and isoleucine degradation Gene Set From KEGG Pathways 2026 proteins participating in the Valine, leucine and isoleucine degradation pathway from the KEGG Pathways 2026 dataset.
Lysine degradation Gene Set From KEGG Pathways 2026 proteins participating in the Lysine degradation pathway from the KEGG Pathways 2026 dataset.
Glycosaminoglycan degradation Gene Set From KEGG Pathways 2026 proteins participating in the Glycosaminoglycan degradation pathway from the KEGG Pathways 2026 dataset.
Other glycan degradation Gene Set From KEGG Pathways 2026 proteins participating in the Other glycan degradation pathway from the KEGG Pathways 2026 dataset.
RNA degradation Gene Set From KEGG Pathways 2026 proteins participating in the RNA degradation pathway from the KEGG Pathways 2026 dataset.

Harmonizome 3.0

COMT Gene

DBH Gene

P3H4 Gene

UFD1L Gene

LOC440489 Gene

ERMARD Gene

EDEM2 Gene

EDEM3 Gene

EDEM1 Gene

UFD1 Gene

PGBDF Gene

LOC101929815 Gene

DRD5P1 Gene

DRD5P2 Gene

DRD4 Gene

DRD5 Gene

DRD2 Gene

DRD3 Gene

DRD1 Gene

LOC101060524 Gene

LOC105369284 Gene

CDNF Gene

LOC102724390 Gene

DORIP1 Gene

Enzymatic degradation of dopamine by COMT Gene Set

Enzymatic degradation of dopamine by COMT Gene Set

Enzymatic degradation of Dopamine by monoamine oxidase Gene Set

Enzymatic degradation of Dopamine by monoamine oxidase Gene Set

comt Gene Set

O-methyltransferase COMT-type Gene Set

COMT Gene Set

COMT Gene Set

COMT Gene Set

dopamine degradation Gene Set

temperature-sensitive enzymatic activity Gene Set

cyp1a2 enzymatic activity Gene Set

enzymatic Gene Set

heparan sulfate proteoglycan biosynthetic process, enzymatic modification Gene Set

heparan sulfate proteoglycan biosynthetic process, enzymatic modification Gene Set

Dopamine beta hydroxylase deficiency Gene Set

dopamine-491 Gene Set

Dopamine Gene Set

arachidonyl dopamine Gene Set

dopamine beta hydroxylase deficiency Gene Set

Dopamine Gene Set

reduced dopamine d2 receptor binding Gene Set

dopamine d2 receptor density; monoamine metabolite concentrations Gene Set

dopamine beta-hydroxylase activity Gene Set

dopamine transporter availability Gene Set

striatal dopamine transporter Gene Set

dopamine Gene Set

dopamine uptake Gene Set

positive regulation of dopamine metabolic process Gene Set

positive regulation of dopamine receptor signaling pathway Gene Set

dopamine biosynthetic process from tyrosine Gene Set

dopamine uptake involved in synaptic transmission Gene Set

regulation of dopamine secretion Gene Set

positive regulation of dopamine biosynthetic process Gene Set

negative regulation of dopamine receptor signaling pathway Gene Set

positive regulation of dopamine secretion Gene Set

regulation of dopamine metabolic process Gene Set

dopamine catabolic process Gene Set

cellular response to dopamine Gene Set

phospholipase c-activating dopamine receptor signaling pathway Gene Set

dopamine biosynthetic process Gene Set

regulation of dopamine biosynthetic process Gene Set

positive regulation of dopamine uptake involved in synaptic transmission Gene Set

negative regulation of dopamine metabolic process Gene Set

dopamine transport Gene Set

regulation of dopamine receptor signaling pathway Gene Set

adenylate cyclase-activating dopamine receptor signaling pathway Gene Set

negative regulation of dopamine secretion Gene Set

adenylate cyclase-inhibiting dopamine receptor signaling pathway Gene Set

dopamine metabolic process Gene Set

dopamine receptor signaling pathway Gene Set

negative regulation of dopamine uptake involved in synaptic transmission Gene Set

regulation of dopamine uptake involved in synaptic transmission Gene Set

response to dopamine Gene Set

d2 dopamine receptor binding Gene Set