Harmonizome 3.0

From <strong>Pathwaystrong> Commons

Prote<strong>instrong>-prote<strong>instrong> <strong>instrong>teractions from low-throughput or high-throughput studies aggregated by <strong>Pathwaystrong> Commons from the follow<strong>instrong>g databases: Reactome, NCI <strong>Pathwaystrong>s, PhosphoSite, HumanCyc, HPRD, PANTHER, DIP, BioGRID, <strong>Instrong>tAct, BIND, Transfac, MiRTarBase, Drugbank, Recon X, Comparative Toxicogenomics Database, and KEGG

From <strong>Pathwaystrong> Figure Optical Character Recognition

Sets of genes/prote<strong>instrong>s extracted from <strong>pathwaystrong> figures <strong>instrong> research publications us<strong>instrong>g optical character recognition

From <strong>Pathwaystrong> Figure Optical Character Recognition

Sets of genes/prote<strong>instrong>s extracted from <strong>pathwaystrong> figures <strong>instrong> research publications us<strong>instrong>g optical character recognition, updated for 2024

From Comparative Toxicogenomics Database

Disease-gene <strong>instrong>teractions from manually curated literature

From DISEASES

Disease gene evidence scores by manual literature curation

From DISEASES

Disease gene evidence scores by <strong>instrong>tegrat<strong>instrong>g experimental data (GWAS)

From DISEASES

Gene-disease co-occurrence scores from text-m<strong>instrong><strong>instrong>g biomedical abstracts

From Genetic Association Database

Gene-disease associations curated from genetic association studies

From Genetic Association Database

Gene-disease associations curated from genetic association studies

From GWASdb

SNP-disease association p-values curated from published GWAS

From Human Phenotype Ontology

Phenotype-caus<strong>instrong>g gene mutations of human phenotypes from disease knowledgebases

From Onl<strong>instrong>e Mendelian <strong>Instrong>heritance <strong>instrong> Man

Disease- or phenotype-caus<strong>instrong>g gene mutations for heritable human diseases or phenotypes curated from biomedical publications

From PhosphoSitePlus

Disease-phosphosite associations curated from literature

From DisGeNET

Gene-disease associations sourced from curated repositories, GWAS catalogues, animal models and the scientific literature

From DISEASES

Disease gene evidence scores by manual literature curation

From DISEASES

Disease gene evidence scores by <strong>instrong>tegrat<strong>instrong>g experimental data (GWAS)

From DISEASES

Gene-disease co-occurrence scores from text-m<strong>instrong><strong>instrong>g biomedical abstracts

From <strong>Pathwaystrong> <strong>Instrong>teraction Database

Sets of prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> <strong>pathwaystrong>s from PID

Hunt<strong>instrong>gton-like neurodegenerative disorder 2

dickkopf WNT signal<strong>instrong>g <strong>pathwaystrong> <strong>instrong>hibitor 1

This gene encodes a member of the dickkopf family of prote<strong>instrong>s. Members of this family are secreted prote<strong>instrong>s characterized by two cyste<strong>instrong>e-rich doma<strong>instrong>s that mediate prote<strong>instrong>-prote<strong>instrong> <strong>instrong>teractions. The encoded prote<strong>instrong> b<strong>instrong>ds to the LRP6 co-receptor and <strong>instrong>hibits beta-caten<strong>instrong>-dependent Wnt signal<strong>instrong>g. This gene plays a role <strong>instrong> embryonic development and may be important <strong>instrong> bone formation <strong>instrong> adults. Elevated expression of this gene has been observed <strong>instrong> numerous human cancers and this prote<strong>instrong> may promote proliferation, <strong>instrong>vasion and growth <strong>instrong> cancer cell l<strong>instrong>es. [provided by RefSeq, Sep 2017]

G prote<strong>instrong> <strong>pathwaystrong> suppressor 1

This gene is known to suppress G-prote<strong>instrong> and mitogen-activated signal transduction <strong>instrong> mammalian cells. The encoded prote<strong>instrong> shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction <strong>instrong> plant cells. [provided by RefSeq, Mar 2016]

G prote<strong>instrong> <strong>pathwaystrong> suppressor 2

This gene encodes a prote<strong>instrong> <strong>instrong>volved <strong>instrong> G prote<strong>instrong>-mitogen-activated prote<strong>instrong> k<strong>instrong>ase (MAPK) signal<strong>instrong>g cascades. When overexpressed <strong>instrong> mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and <strong>instrong>terfere with JNK activity, suggest<strong>instrong>g that the function of this gene may be signal repression. The encoded prote<strong>instrong> is an <strong>instrong>tegral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex <strong>instrong>hibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator prote<strong>instrong> 1) function. [provided by RefSeq, Jul 2008]

epidermal growth factor receptor <strong>pathwaystrong> substrate 15-like 1

Enables cadher<strong>instrong> b<strong>instrong>d<strong>instrong>g activity. Predicted to be <strong>instrong>volved <strong>instrong> endosomal transport and synaptic vesicle endocytosis. Located <strong>instrong> membrane. [provided by Alliance of Genome Resources, Mar 2025]

dickkopf WNT signal<strong>instrong>g <strong>pathwaystrong> <strong>instrong>hibitor 4

This gene encodes a prote<strong>instrong> that is a member of the dickkopf family. The secreted prote<strong>instrong> conta<strong>instrong>s two cyste<strong>instrong>e rich regions and is <strong>instrong>volved <strong>instrong> embryonic development through its <strong>instrong>teractions with the Wnt signal<strong>instrong>g <strong>pathwaystrong>. Activity of this prote<strong>instrong> is modulated by b<strong>instrong>d<strong>instrong>g to the Wnt co-receptor and the co-factor kremen 2. [provided by RefSeq, Jul 2008]

dickkopf WNT signal<strong>instrong>g <strong>pathwaystrong> <strong>instrong>hibitor 3

This gene encodes a prote<strong>instrong> that is a member of the dickkopf family. The secreted prote<strong>instrong> conta<strong>instrong>s two cyste<strong>instrong>e rich regions and is <strong>instrong>volved <strong>instrong> embryonic development through its <strong>instrong>teractions with the Wnt signal<strong>instrong>g <strong>pathwaystrong>. The expression of this gene is decreased <strong>instrong> a variety of cancer cell l<strong>instrong>es and it may function as a tumor suppressor gene. Alternative splic<strong>instrong>g results <strong>instrong> multiple transcript variants encod<strong>instrong>g the same prote<strong>instrong>. [provided by RefSeq, Jul 2008]

TOR signal<strong>instrong>g <strong>pathwaystrong> regulator

TIPRL is an <strong>instrong>hibitory regulator of prote<strong>instrong> phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010]

non-prote<strong>instrong> cod<strong>instrong>g RNA, associated with MAP k<strong>instrong>ase <strong>pathwaystrong> and growth arrest

epidermal growth factor receptor <strong>pathwaystrong> substrate 15

This gene encodes a prote<strong>instrong> that is part of the EGFR <strong>pathwaystrong>. The prote<strong>instrong> is present at clather<strong>instrong>-coated pits and is <strong>instrong>volved <strong>instrong> receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene <strong>instrong> acute myelogeneous leukemias. Alternative splic<strong>instrong>g results <strong>instrong> multiple transcript variants encod<strong>instrong>g dist<strong>instrong>ct isoforms. [provided by RefSeq, May 2009]

dickkopf WNT signal<strong>instrong>g <strong>pathwaystrong> <strong>instrong>hibitor 2

This gene encodes a prote<strong>instrong> that is a member of the dickkopf family. The secreted prote<strong>instrong> conta<strong>instrong>s two cyste<strong>instrong>e rich regions and is <strong>instrong>volved <strong>instrong> embryonic development through its <strong>instrong>teractions with the Wnt signal<strong>instrong>g <strong>pathwaystrong>. It can act as either an agonist or antagonist of Wnt/beta-caten<strong>instrong> signal<strong>instrong>g, depend<strong>instrong>g on the cellular context and the presence of the co-factor kremen 2. Activity of this prote<strong>instrong> is also modulated by b<strong>instrong>d<strong>instrong>g to the Wnt co-receptor LDL-receptor related prote<strong>instrong> 6 (LRP6). [provided by RefSeq, Jul 2008]

tumor prote<strong>instrong> p53 <strong>pathwaystrong> corepressor 1 (non-prote<strong>instrong> cod<strong>instrong>g)

Predicted to act upstream of or with<strong>instrong> negative regulation of gene expression. Predicted to be part of ribonucleoprote<strong>instrong> complex. [provided by Alliance of Genome Resources, Mar 2025]

G prote<strong>instrong> <strong>pathwaystrong> suppressor 2 pseudogene 1

G prote<strong>instrong> <strong>pathwaystrong> suppressor 2 pseudogene 2

epidermal growth factor receptor <strong>pathwaystrong> substrate 8

This gene encodes a member of the EPS8 family. This prote<strong>instrong> conta<strong>instrong>s one PH doma<strong>instrong> and one SH3 doma<strong>instrong>. It functions as part of the EGFR <strong>pathwaystrong>, though its exact role has not been determ<strong>instrong>ed. Highly similar prote<strong>instrong>s <strong>instrong> other organisms are <strong>instrong>volved <strong>instrong> the transduction of signals from Ras to Rac and growth factor-mediated act<strong>instrong> remodel<strong>instrong>g. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

tissue factor <strong>pathwaystrong> <strong>instrong>hibitor 2

This gene encodes a member of the Kunitz-type ser<strong>instrong>e prote<strong>instrong>ase <strong>instrong>hibitor family. The prote<strong>instrong> can <strong>instrong>hibit a variety of ser<strong>instrong>e proteases <strong>instrong>clud<strong>instrong>g factor VIIa/tissue factor, factor Xa, plasm<strong>instrong>, tryps<strong>instrong>, chymotrysp<strong>instrong> and plasma kallikre<strong>instrong>. This gene has been identified as a tumor suppressor gene <strong>instrong> several types of cancer. Alternative splic<strong>instrong>g results <strong>instrong> multiple transcript variants. [provided by RefSeq, Aug 2012]

WNT1 <strong>instrong>ducible signal<strong>instrong>g <strong>pathwaystrong> prote<strong>instrong> 2

This gene encodes a member of the WNT1 <strong>instrong>ducible signal<strong>instrong>g <strong>pathwaystrong> (WISP) prote<strong>instrong> subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cyste<strong>instrong>e-rich, glycosylated signal<strong>instrong>g prote<strong>instrong>s that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cyste<strong>instrong>e-rich doma<strong>instrong>s: <strong>instrong>sul<strong>instrong>-like growth factor-b<strong>instrong>d<strong>instrong>g doma<strong>instrong>, von Willebrand factor type C module, thrombospond<strong>instrong> doma<strong>instrong> and C-term<strong>instrong>al cyst<strong>instrong>e knot-like (CT) doma<strong>instrong>. The encoded prote<strong>instrong> lacks the CT doma<strong>instrong> which is implicated <strong>instrong> dimerization and hepar<strong>instrong> b<strong>instrong>d<strong>instrong>g. It is 72% identical to the mouse prote<strong>instrong> at the am<strong>instrong>o acid level. This gene may be downstream <strong>instrong> the WNT1 signal<strong>instrong>g <strong>pathwaystrong> that is relevant to malignant transformation. Its expression <strong>instrong> colon tumors is reduced while the other two WISP members are overexpressed <strong>instrong> colon tumors. It is expressed at high levels <strong>instrong> bone tissue, and may play an important role <strong>instrong> modulat<strong>instrong>g bone turnover. [provided by RefSeq, Jul 2008]

WNT1 <strong>instrong>ducible signal<strong>instrong>g <strong>pathwaystrong> prote<strong>instrong> 3

This gene encodes a member of the WNT1 <strong>instrong>ducible signal<strong>instrong>g <strong>pathwaystrong> (WISP) prote<strong>instrong> subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cyste<strong>instrong>e-rich, glycosylated signal<strong>instrong>g prote<strong>instrong>s that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cyste<strong>instrong>e-rich doma<strong>instrong>s: <strong>instrong>sul<strong>instrong>-like growth factor-b<strong>instrong>d<strong>instrong>g doma<strong>instrong>, von Willebrand factor type C module, thrombospond<strong>instrong> doma<strong>instrong> and C-term<strong>instrong>al cyst<strong>instrong>e knot-like doma<strong>instrong>. This gene is overexpressed <strong>instrong> colon tumors. It may be downstream <strong>instrong> the WNT1 signal<strong>instrong>g <strong>pathwaystrong> that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, <strong>instrong>dicat<strong>instrong>g that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encod<strong>instrong>g different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

WNT1 <strong>instrong>ducible signal<strong>instrong>g <strong>pathwaystrong> prote<strong>instrong> 1

This gene encodes a member of the WNT1 <strong>instrong>ducible signal<strong>instrong>g <strong>pathwaystrong> (WISP) prote<strong>instrong> subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cyste<strong>instrong>e-rich, glycosylated signal<strong>instrong>g prote<strong>instrong>s that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cyste<strong>instrong>e-rich doma<strong>instrong>s: <strong>instrong>sul<strong>instrong>-like growth factor-b<strong>instrong>d<strong>instrong>g doma<strong>instrong>, von Willebrand factor type C module, thrombospond<strong>instrong> doma<strong>instrong> and C-term<strong>instrong>al cyst<strong>instrong>e knot-like doma<strong>instrong>. This gene may be downstream <strong>instrong> the WNT1 signal<strong>instrong>g <strong>pathwaystrong> that is relevant to malignant transformation. It is expressed at a high level <strong>instrong> fibroblast cells, and overexpressed <strong>instrong> colon tumors. The encoded prote<strong>instrong> b<strong>instrong>ds to decor<strong>instrong> and biglycan, two members of a family of small leuc<strong>instrong>e-rich proteoglycans present <strong>instrong> the extracellular matrix of connective tissue, and possibly prevents the <strong>instrong>hibitory activity of decor<strong>instrong> and biglycan <strong>instrong> tumor cell proliferation. It also attenuates p53-mediated apoptosis <strong>instrong> response to DNA damage through activation of the Akt k<strong>instrong>ase. It is 83% identical to the mouse prote<strong>instrong> at the am<strong>instrong>o acid level. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2011]

WNT signal<strong>instrong>g <strong>pathwaystrong> activat<strong>instrong>g non-cod<strong>instrong>g RNA

tissue factor <strong>pathwaystrong> <strong>instrong>hibitor (lipoprote<strong>instrong>-associated coagulation <strong>instrong>hibitor)

This gene encodes a Kunitz-type ser<strong>instrong>e protease <strong>instrong>hibitor that regulates the tissue factor (TF)-dependent <strong>pathwaystrong> of blood coagulation. The coagulation process <strong>instrong>itiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibr<strong>instrong> clot. The product of this gene <strong>instrong>hibits the activated factor X and VIIa-TF proteases <strong>instrong> an autoregulatory loop. <strong>Instrong>hibition of the encoded prote<strong>instrong> restores hemostasis <strong>instrong> animal models of hemophilia. This gene encodes multiple prote<strong>instrong> isoforms that differ <strong>instrong> their <strong>instrong>hibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]

epidermal growth factor receptor <strong>pathwaystrong> substrate 15 pseudogene 1

G prote<strong>instrong> <strong>pathwaystrong> suppressor 1 pseudogene

SREBF <strong>pathwaystrong> regulator <strong>instrong> golgi 1

<strong>Instrong>volved <strong>instrong> positive regulation of SREBP signal<strong>instrong>g <strong>pathwaystrong>. Located <strong>instrong> Golgi membrane. [provided by Alliance of Genome Resources, Mar 2025]

non-cod<strong>instrong>g RNA <strong>instrong> the aldehyde dehydrogenase 1A <strong>pathwaystrong>

From WikiPathways Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the ERK <strong>pathwaystrong> <strong>instrong> Hunt<strong>instrong>gton <strong><strong>39strong>strong> s disease <strong>pathwaystrong> from the Wiki<strong>Pathwaystrong>s <strong>Pathwaystrong>s 2024 dataset.

From GAD Gene-Disease Associations

genes associated with the disease addison disease; addison's disease; diabetes mellitus, <strong>instrong>sul<strong>instrong>-dependent; diabetes mellitus, type 1; graves disease; graves' disease; hashimoto disease; polyendocr<strong>instrong>opathies, autoimmune <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From CTD Gene-Disease Associations

genes/prote<strong>instrong>s associated with the disease Hunt<strong>instrong>gton Disease-Like 2 from the curated CTD Gene-Disease Associations dataset.

From CTD Gene-Disease Associations

genes/prote<strong>instrong>s associated with the disease Hunt<strong>instrong>gton Disease-Like 1 from the curated CTD Gene-Disease Associations dataset.

From CTD Gene-Disease Associations

genes/prote<strong>instrong>s associated with the disease Hunt<strong>instrong>gton Disease-Like 3 from the curated CTD Gene-Disease Associations dataset.

From CTD Gene-Disease Associations

genes/prote<strong>instrong>s associated with the disease Hunt<strong>instrong>gton Disease from the curated CTD Gene-Disease Associations dataset.

From DISEASES Curated Gene-Disease Association Evidence Scores

genes <strong>instrong>voled <strong>instrong> the disease hunt<strong>instrong>gton's disease from the DISEASES Curated Gene-Disease Assocation Evidence Scores dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores

genes co-occur<strong>instrong>g with the disease hunt<strong>instrong>gton's disease <strong>instrong> abstracts of biomedical publications from the DISEASES Text-m<strong>instrong><strong>instrong>g Gene-Disease Assocation Evidence Scores dataset.

From GAD Gene-Disease Associations

genes associated with the disease hunt<strong>instrong>gton disease; myoclonic cerebellar dyssynergia; sp<strong>instrong>ocerebellar ataxias <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease hunt<strong>instrong>gton disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease carotid artery <strong>instrong>tima-media thickness; sp<strong>instrong>ocerebellar ataxia; hunt<strong>instrong>gton's disease; myotonic dystrophy <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease hunt<strong>instrong>gton's disease; ataxia (sca) <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease ataxia; fragile x syndrome; hunt<strong>instrong>gton disease; tremor <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic progressive chorea; hunt<strong>instrong>gton disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease hunt<strong>instrong>gton's disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic progressive chorea; hunt<strong>instrong>gton disease; <strong>instrong>sul<strong>instrong> resistance <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease atrophy; hunt<strong>instrong>gton disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Hunt<strong>instrong>gton Disease phenotype by text-m<strong>instrong><strong>instrong>g GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the hunt<strong>instrong>gton disease-like 3 phenotype from the curated OMIM Gene-Disease Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the hunt<strong>instrong>gton disease-like 2 phenotype from the curated OMIM Gene-Disease Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the hunt<strong>instrong>gton disease-like 1 phenotype from the curated OMIM Gene-Disease Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the hunt<strong>instrong>gton disease phenotype from the curated OMIM Gene-Disease Associations dataset.

From PANTHER Pathways

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Hunt<strong>instrong>gton disease <strong>pathwaystrong> from the PANTHER <strong>Pathwaystrong>s dataset.

From PhosphoSitePlus Phosphosite-Disease Associations

prote<strong>instrong>s associated with the disease Hunt<strong>instrong>gton's disease from the curated PhosphoSitePlus Phosphosite-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Hunt<strong>instrong>gton Disease <strong>instrong> GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Ak<strong>instrong>etic-Rigid Variant Of Hunt<strong>instrong>gton Disease <strong>instrong> GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Juvenile Hunt<strong>instrong>gton Disease <strong>instrong> GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From WikiPathways Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Effect of omega 3 PUFA on Hunt<strong>instrong>gton <strong><strong>39strong>strong> s disease <strong>pathwaystrong>s <strong>pathwaystrong> from the Wiki<strong>Pathwaystrong>s <strong>Pathwaystrong>s 2024 dataset.

From DISEASES Curated Gene-Disease Association Evidence Scores 2025

genes <strong>instrong>voled <strong>instrong> the disease Hunt<strong>instrong>gton's disease from the DISEASES Curated Gene-Disease Association Evidence Scores 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occur<strong>instrong>g with the disease Hunt<strong>instrong>gton's disease <strong>instrong> abstracts of biomedical publications from the DISEASES Text-m<strong>instrong><strong>instrong>g Gene-Disease Assocation Evidence Scores 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occur<strong>instrong>g with the disease Hunt<strong>instrong>gton's disease-like 1 <strong>instrong> abstracts of biomedical publications from the DISEASES Text-m<strong>instrong><strong>instrong>g Gene-Disease Assocation Evidence Scores 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occur<strong>instrong>g with the disease Hunt<strong>instrong>gton's disease-like 2 <strong>instrong> abstracts of biomedical publications from the DISEASES Text-m<strong>instrong><strong>instrong>g Gene-Disease Assocation Evidence Scores 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Hunt<strong>instrong>gton disease-like phenotype from the curated Cl<strong>instrong>Var Gene-Phenotype Associations 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Hunt<strong>instrong>gton disease phenotype from the curated Cl<strong>instrong>Var Gene-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Hunt<strong>instrong>gton's disease (age at onset) phenotype <strong>instrong> GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Hunt<strong>instrong>gton's disease progression phenotype <strong>instrong> GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From KEGG Pathways 2026

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Hunt<strong>instrong>gton disease <strong>pathwaystrong> from the KEGG <strong>Pathwaystrong>s 2026 dataset.

From Biocarta Pathways

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the <strong>erkstrong> and pi-3 k<strong>instrong>ase are necessary for collagen b<strong>instrong>d<strong>instrong>g <strong>instrong> corneal epithelia <strong>pathwaystrong> from the Biocarta <strong>Pathwaystrong>s dataset.

From CORUM Protein Complexes

prote<strong>instrong>s <strong>instrong> the Ksr1-Mek-Braf-<strong>Erkstrong> complex, EGF <strong>instrong>duced prote<strong>instrong> complex from the CORUM Prote<strong>instrong> Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occur<strong>instrong>g with the biological term <strong>erkstrong> <strong>instrong> literature-supported statements describ<strong>instrong>g functions of genes from the GeneRIF Biological Term Annotations dataset.

From Phosphosite Textmining Biological Term Annotations

prote<strong>instrong>s co-occur<strong>instrong>g with the biological term <strong>erkstrong> <strong>instrong> abstracts of publications describ<strong>instrong>g phosphosites from the Phosphosite Textm<strong>instrong><strong>instrong>g Biological Term Annotations dataset.

From Phosphosite Textmining Biological Term Annotations

prote<strong>instrong>s co-occur<strong>instrong>g with the biological term <strong>erkstrong>-dependent <strong>instrong> abstracts of publications describ<strong>instrong>g phosphosites from the Phosphosite Textm<strong>instrong><strong>instrong>g Biological Term Annotations dataset.

From Reactome Pathways 2014

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the ERK/MAPK targets <strong>pathwaystrong> from the Reactome <strong>Pathwaystrong>s dataset.

From Reactome Pathways 2014

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the ERK activation <strong>pathwaystrong> from the Reactome <strong>Pathwaystrong>s dataset.

From Reactome Pathways 2014

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Prolonged ERK activation events <strong>pathwaystrong> from the Reactome <strong>Pathwaystrong>s dataset.

From DeepCoverMOA Drug Mechanisms of Action

prote<strong>instrong>s with high or low expression <strong>instrong> TCS ERK 11e relative to other prote<strong>instrong>s from the DeepCoverMOA Drug Mechanisms of Action dataset.

From WikiPathways Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the FBXL10 enhancement of MAP ERK signal<strong>instrong>g <strong>instrong> diffuse large B cell lymphoma <strong>pathwaystrong> from the Wiki<strong>Pathwaystrong>s <strong>Pathwaystrong>s 2024 dataset.

From Reactome Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the ERK/MAPK targets <strong>pathwaystrong> from the Reactome <strong>Pathwaystrong>s 2024 dataset.

From Reactome Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Prolonged ERK activation events <strong>pathwaystrong> from the Reactome <strong>Pathwaystrong>s 2024 dataset.

From DGIdb Drug Targets 2026

<strong>instrong>teract<strong>instrong>g prote<strong>instrong>s for the ERK INHIBITOR CC-90003 drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

<strong>instrong>teract<strong>instrong>g prote<strong>instrong>s for the ERK INHIBITOR III drug from theDGIdb Drug Targets 2026 dataset.

From GeneRIF Biological Term Annotations

genes co-occur<strong>instrong>g with the biological term hunt<strong>instrong>gton <strong>instrong> literature-supported statements describ<strong>instrong>g functions of genes from the GeneRIF Biological Term Annotations dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_CNS - Bra<strong>instrong> - Striatum (MMHCC)_GSE9857 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_CNS - Bra<strong>instrong> (MMHCC)_GSE857 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_CNS - Bra<strong>instrong> - Striatum (MMHCC)_GSE3583 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_Bra<strong>instrong>_GSE3621 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_CNS - Bra<strong>instrong> - Cerebellum (MMHCC)_GSE3248 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_CNS - Bra<strong>instrong> - Striatum (MMHCC)_GSE5786 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_CNS - Bra<strong>instrong> - Striatum (MMHCC)_GSE7958 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_Lymphocyte_GSE8762 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_CNS - Bra<strong>instrong> - Striatum (MMHCC)_GSE9375 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed dur<strong>instrong>g Hunt<strong>instrong>gton's Disease_Blood_GSE1751 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary artery disease; coronary disease; coronary heart disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease arthritis, rheumatoid; coronary artery disease; crohn disease; crohn's disease; diabetes mellitus; hypertension; rheumatoid arthritis <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease activated prote<strong>instrong> c resistance; chronic ulcerative colitis; colitis, ulcerative; crohn disease; crohn's disease; hyperhomocyste<strong>instrong>emia; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic ulcerative colitis; colitis, ulcerative; crohn disease; crohn's disease; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; disease progression <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; granuloma; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease graves disease; graves' disease; hashimoto disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease arthritis, rheumatoid; crohn disease; crohn's disease; diabetes mellitus; disease; rheumatoid arthritis <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; park<strong>instrong>son disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease addison disease; graves disease; hashimoto disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; disease susceptibility <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; amyotrophic lateral sclerosis; multiple system atrophy; nervous system diseases; park<strong>instrong>son disease; polyradiculoneuropathy, chronic <strong>instrong>flammatory demyel<strong>instrong>at<strong>instrong>g; tauopathies <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease addison disease; autoimmune diseases; graves disease; hashimoto disease; thyroid diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic ulcerative colitis; colitis, ulcerative; crohn disease; crohn's disease; diabetes mellitus, <strong>instrong>sul<strong>instrong>-dependent; diabetes mellitus, type 1; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic ulcerative colitis; colitis, ulcerative; crohn disease; crohn's disease; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases; peripheral vascular diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; cardiovascular diseases; chronic disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease park<strong>instrong>sons disease; alzheimers disease; ataxia; hunt<strong>instrong>gtons disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic ulcerative colitis; colitis, ulcerative; colorectal neoplasms; crohn disease; crohn's disease; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic ulcerative colitis; colitis, ulcerative; crohn disease; crohn's disease; disease susceptibility; substance-related disorders <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic ulcerative colitis; colitis, ulcerative; crohn disease; crohn's disease; hyperhomocyste<strong>instrong>emia; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases; thromboembolism <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; dementia; dementia, vascular; lewy body disease; pick disease of the bra<strong>instrong> <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease graves disease; graves' disease; hashimoto disease; hypothyroidism <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; dementia; dementia, vascular; lewy body disease; neurodegenerative diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; ataxia; diabetes mellitus, type 2; disease; obesity; park<strong>instrong>son disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease arthritis, rheumatoid; coronary artery disease; crohn disease; crohn's disease; diabetes mellitus type ii; diabetes mellitus, <strong>instrong>sul<strong>instrong>-dependent; diabetes mellitus, type 1; diabetes mellitus, type 2; hypertension; rheumatoid arthritis <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease autoimmune thyroiditis; graves disease; graves' disease; hashimoto disease; thyroiditis, autoimmune <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease colitis; crohn disease; crohn's disease; disease models, animal <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic ulcerative colitis; colitis, ulcerative; crohn disease; crohn's disease; <strong>instrong>flammation; <strong>instrong>flammatory bowel disease, nos; <strong>instrong>flammatory bowel diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; graft vs host disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Kidney disease (end stage renal disease vs non-end stage renal disease) <strong>instrong> type 1 diabetes phenotype <strong>instrong> GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GO Biological Process Annotations 2015

genes participat<strong>instrong>g <strong>instrong> the wnt signal<strong>instrong>g <strong>pathwaystrong>, calcium modulat<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participat<strong>instrong>g <strong>instrong> the wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participat<strong>instrong>g <strong>instrong> the regulation of wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participat<strong>instrong>g <strong>instrong> the positive regulation of wnt signal<strong>instrong>g <strong>pathwaystrong> by bmp signal<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participat<strong>instrong>g <strong>instrong> the positive regulation of wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From PANTHER Pathways

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Heterotrimeric G-prote<strong>instrong> signal<strong>instrong>g <strong>pathwaystrong>-Gi alpha and Gs alpha mediated <strong>pathwaystrong> <strong>pathwaystrong> from the PANTHER <strong>Pathwaystrong>s dataset.

From PANTHER Pathways

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Heterotrimeric G-prote<strong>instrong> signal<strong>instrong>g <strong>pathwaystrong>-Gq alpha and Go alpha mediated <strong>pathwaystrong> <strong>pathwaystrong> from the PANTHER <strong>Pathwaystrong>s dataset.

From GO Biological Process Annotations 2023

genes participat<strong>instrong>g <strong>instrong> the Wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participat<strong>instrong>g <strong>instrong> the positive regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong>, calcium modulat<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participat<strong>instrong>g <strong>instrong> the positive regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participat<strong>instrong>g <strong>instrong> the Wnt signal<strong>instrong>g <strong>pathwaystrong>, calcium modulat<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participat<strong>instrong>g <strong>instrong> the positive regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong> by BMP signal<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participat<strong>instrong>g <strong>instrong> the regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participat<strong>instrong>g <strong>instrong> the regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong>, calcium modulat<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes perform<strong>instrong>g the coreceptor activity <strong>instrong>volved <strong>instrong> Wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Biological Process Annotations 2025

genes participat<strong>instrong>g <strong>instrong> the Wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participat<strong>instrong>g <strong>instrong> the positive regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong>, calcium modulat<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participat<strong>instrong>g <strong>instrong> the positive regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participat<strong>instrong>g <strong>instrong> the Wnt signal<strong>instrong>g <strong>pathwaystrong>, calcium modulat<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participat<strong>instrong>g <strong>instrong> the regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong>, planar cell polarity <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participat<strong>instrong>g <strong>instrong> the regulation of Wnt signal<strong>instrong>g <strong>pathwaystrong>, calcium modulat<strong>instrong>g <strong>pathwaystrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores

genes co-occur<strong>instrong>g with the disease visual <strong>pathwaystrong> disease <strong>instrong> abstracts of biomedical publications from the DISEASES Text-m<strong>instrong><strong>instrong>g Gene-Disease Assocation Evidence Scores dataset.

From GWASdb SNP-Disease Associations

genes associated with the disease visual <strong>pathwaystrong> disease <strong>instrong> GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

From PANTHER Pathways

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Alzheimer disease-amyloid secretase <strong>pathwaystrong> <strong>pathwaystrong> from the PANTHER <strong>Pathwaystrong>s dataset.

From PANTHER Pathways

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Alzheimer disease-presenil<strong>instrong> <strong>pathwaystrong> <strong>pathwaystrong> from the PANTHER <strong>Pathwaystrong>s dataset.

From WikiPathways Pathways 2014

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Park<strong>instrong>sons Disease <strong>Pathwaystrong>(Homo sapiens) <strong>pathwaystrong> from the Wiki<strong>Pathwaystrong>s <strong>Pathwaystrong>s 2014 dataset.

From WikiPathways Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Park<strong>instrong>son <strong><strong>39strong>strong> s disease <strong>pathwaystrong> <strong>pathwaystrong> from the Wiki<strong>Pathwaystrong>s <strong>Pathwaystrong>s 2024 dataset.

From WikiPathways Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Polycystic kidney disease <strong>pathwaystrong> <strong>pathwaystrong> from the Wiki<strong>Pathwaystrong>s <strong>Pathwaystrong>s 2024 dataset.

From WikiPathways Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Prion disease <strong>pathwaystrong> <strong>pathwaystrong> from the Wiki<strong>Pathwaystrong>s <strong>Pathwaystrong>s 2024 dataset.

From WikiPathways Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the STING <strong>pathwaystrong> <strong>instrong> Kawasaki like disease and COVID 19 <strong>pathwaystrong> from the Wiki<strong>Pathwaystrong>s <strong>Pathwaystrong>s 2024 dataset.

From Reactome Pathways 2024

prote<strong>instrong>s participat<strong>instrong>g <strong>instrong> the Pentose phosphate <strong>pathwaystrong> disease <strong>pathwaystrong> from the Reactome <strong>Pathwaystrong>s 2024 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occur<strong>instrong>g with the disease Visual <strong>pathwaystrong> disease <strong>instrong> abstracts of biomedical publications from the DISEASES Text-m<strong>instrong><strong>instrong>g Gene-Disease Assocation Evidence Scores 2025 dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; <strong>instrong>flammation <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; melanoma; sk<strong>instrong> neoplasms <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease heart disease, ischemic; peripheral arterial disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cardiovascular diseases; coronary disease; coronary heart disease; <strong>instrong>sul<strong>instrong> resistance; obesity <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; hyperhomocyste<strong>instrong>emia; pulmonary embolism; pulmonary embolisms; syndrome; thrombophilia <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; dementia; dementia, vascular; neurodegenerative diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cerebrovascular disorders; coronary disease; coronary heart disease; diabetes mellitus; hypercholesterolemia; hyperhomocyste<strong>instrong>emia; hypertension; ret<strong>instrong>al ve<strong>instrong> occlusion; thrombophilia; venous thrombosis <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease graves disease; hashimoto disease; hyperthyroidism; hypothyroidism <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease acute coronary syndrome; atherosclerosis; coronary disease; coronary heart disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; granuloma <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; familial mediterranean fever <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; hypercholesterolemia <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; myocardial <strong>instrong>farction; syndrome <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease liver disease; wilson disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic obstructive pulmonary disease/copd; bronchiectatic disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; thromboembolism <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; dna damage; genomic <strong>instrong>stability <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; hemochromatosis; <strong>instrong>flammation <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease park<strong>instrong>son's disease ; alzheimer's disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; diabetes mellitus type ii; diabetes mellitus, type 2 <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease heart disease, ischemic; cerebrovascular disease, ischemic <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; cerebral amyloid angiopathy <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease atrial fibrillation; blood loss, surgical; coronary disease; coronary heart disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; diabetic angiopathies; myocardial <strong>instrong>farction <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease chronic ulcerative colitis; colitis, ulcerative; crohn disease; crohn's disease; <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; duodenal diseases; stomach diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease crohn disease; crohn's disease; sarcoidosis <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; familial type 3 hyperlipoprote<strong>instrong>aemia; hyper<strong>instrong>sul<strong>instrong>ism; hyperlipoprote<strong>instrong>emia type iii; peripheral vascular diseases <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease addison's disease; graves' disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease kidney disease; vascular disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease apoplexy; bra<strong>instrong> ischemia; coronary disease; coronary heart disease; stroke <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease graves disease; graves ophthalmopathy; hashimoto disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; hypertension <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alcohol amnestic disorder; alcoholism; alzheimer disease; alzheimer's disease <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease diabetes, type 1; addison's disease; graves' disease; thyroiditis, chronic lymphocytic <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; olfaction disorders <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; aphasia, primary progressive; dementia; nerve degeneration <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; encephalitis, herpes simplex; herpes encephalitis <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease coronary disease; coronary heart disease; diabetes mellitus <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; amyotrophic lateral sclerosis; aphasia, primary progressive <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; memory disorders <strong>instrong> GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.