Harmonizome 3.0

From Nuclear Receptor Signaling Atlas

Proteins identified in complexes isolated from cultured cells

From Nuclear Receptor Signaling Atlas

Protein-protein interactions inferred from membership in complexes

eukaryotic translation initiation factor 3, subunit E pseudogene 3

eukaryotic translation initiation factor 3, subunit E pseudogene 2

eukaryotic translation initiation factor 3, subunit E pseudogene 1

eukaryotic translation initiation factor 4E family member 1B

Predicted to enable RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 4F complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit F pseudogene

eukaryotic translation initiation factor 3, subunit E pseudogene 4

eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa pseudogene

eukaryotic translation initiation factor 4E binding protein 2 pseudogene

eukaryotic translation initiation factor 4H pseudogene 1

eukaryotic translation initiation factor 4E pseudogene 1

eukaryotic translation initiation factor 2-alpha kinase 1 pseudogene

eukaryotic translation initiation factor 3, subunit F pseudogene 1

eukaryotic translation initiation factor 3, subunit F pseudogene 2

eukaryotic translation initiation factor 3, subunit F pseudogene 3

eukaryotic translation initiation factor 4E binding protein 1

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 4E binding protein 3

This gene encodes a member of the EIF4EBP family, which consists of proteins that bind to eukaryotic translation initiation factor 4E and regulate its assembly into EIF4F, the multi-subunit translation initiation factor that recognizes the mRNA cap structure. Read-through transcription from the neighboring upstream gene (MASK or ANKHD1) generates a transcript (MASK-BP3) that encodes a protein comprised of the MASK protein sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Oct 2010]

transcription initiation factor TFIID subunit 4-like

eukaryotic translation initiation factor 3 subunit A-like

eukaryotic translation initiation factor 5A-like 1

Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to be located in endoplasmic reticulum membrane and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 1B

Enables RNA binding activity. Predicted to be involved in regulation of translational initiation. Predicted to be part of eukaryotic 43S preinitiation complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 4A2 pseudogene 1

eukaryotic translation initiation factor 4A2 pseudogene 3

eukaryotic translation initiation factor 4A2 pseudogene 2

eukaryotic translation initiation factor 4A2 pseudogene 4

eukaryotic translation initiation factor 2A pseudogene 4

eukaryotic translation initiation factor 2A pseudogene 1

eukaryotic translation initiation factor 2A pseudogene 3

fin bud initiation factor homolog (zebrafish)

Predicted to enable protein homodimerization activity. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

mitochondrial translational initiation factor 3

This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009]

mitochondrial translational initiation factor 2

During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. [provided by RefSeq, Mar 2016]

eukaryotic translation initiation factor 3, subunit J pseudogene

eukaryotic translation initiation factor 1 pseudogene 3

eukaryotic translation initiation factor 1 pseudogene 2

eukaryotic translation initiation factor 1 pseudogene 1

eukaryotic translation initiation factor 1 pseudogene 4

eukaryotic translation initiation factor 4H pseudogene 2

eukaryotic translation initiation factor 4E pseudogene 2

eukaryotic translation initiation factor 4E pseudogene 4

eukaryotic translation initiation factor 4E pseudogene 5

eukaryotic translation initiation factor 4A3 pseudogene 1

eukaryotic translation initiation factor 2, subunit 2 beta pseudogene 1

eukaryotic translation initiation factor 2, subunit 2 beta pseudogene 3

eukaryotic translation initiation factor 2, subunit 2 beta pseudogene 2

eukaryotic translation initiation factor 2, subunit 2 beta pseudogene 5

eukaryotic translation initiation factor 2, subunit 2 beta pseudogene 4

eukaryotic translation initiation factor 2, subunit 2 beta pseudogene 7

eukaryotic translation initiation factor 2, subunit 2 beta pseudogene 6

eukaryotic translation initiation factor 5A2

Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 4E binding protein 2 pseudogene 1

eukaryotic translation initiation factor 4E binding protein 2 pseudogene 3

eukaryotic translation initiation factor 4E binding protein 2 pseudogene 2

eukaryotic translation initiation factor 4E family member 3

EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]

eukaryotic translation initiation factor 4E family member 2

Enables RNA 7-methylguanosine cap binding activity; mRNA cap binding activity; and ubiquitin protein ligase binding activity. Involved in negative regulation of translational initiation; negative regulation of type I interferon-mediated signaling pathway; and rescue of stalled ribosome. Acts upstream of with a positive effect on miRNA-mediated gene silencing by inhibition of translation. Acts upstream of or within negative regulation of translation. Located in P-body. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 4E nuclear import factor 1

The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

eukaryotic translation initiation factor 5A2 pseudogene 1

eukaryotic translation initiation factor 3, subunit K pseudogene 1

eukaryotic translation initiation factor 3, subunit C

Enables ribosome binding activity. Contributes to translation initiation factor activity. Involved in positive regulation of translation and translational initiation. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit D

Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 3, subunit G

This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy. [provided by RefSeq, Jul 2016]

transcription initiation factor TFIID subunit 4-like

eukaryotic translation initiation factor 3, subunit C-like

The protein encoded by this gene is a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex. The encoded protein is nearly identical to another protein, eIF3c, from a related gene. The eIF3 complex binds the 40S ribosome and mRNAs to enable translation initiation. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]

eukaryotic translation initiation factor 3, subunit K pseudogene 2

eukaryotic translation initiation factor 3, subunit H

Enables metal-dependent deubiquitinase activity. Contributes to translation initiation factor activity. Involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process and translational initiation. Located in extracellular exosome and membrane. Part of eukaryotic translation initiation factor 3 complex. Implicated in breast cancer; prostate cancer; and prostate carcinoma. Biomarker of prostate cancer. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit I

Contributes to translation initiation factor activity. Involved in translational initiation. Located in extracellular exosome. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit J

This gene encodes a core subunit of the eukaryotic initiation factor 3 complex, which participates in the initiation of translation by aiding in the recruitment of protein and mRNA components to the 40S ribosome. There are pseudogenes for this gene on chromosomes 1, 3, and 9. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]

eukaryotic translation initiation factor 3, subunit K

The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).[supplied by OMIM, Mar 2008]

eukaryotic translation initiation factor 3, subunit L

Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in translational initiation and viral translational termination-reinitiation. Located in membrane. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit M

This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome. [provided by RefSeq, Dec 2011]

eukaryotic translation initiation factor 3, subunit A

Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation; formation of cytoplasmic translation initiation complex; and viral translational termination-reinitiation. Located in cytosol; nucleolus; and nucleoplasm. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit B

Enables RNA binding activity. Contributes to translation initiation factor activity. Involved in several processes, including IRES-dependent viral translational initiation; translational initiation; and viral translational termination-reinitiation. Located in cytoplasmic stress granule. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit E

Enables RNA binding activity and cadherin binding activity. Contributes to translation initiation factor activity. Involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; positive regulation of translation; and translational initiation. Located in PML body and cytosol. Part of eukaryotic translation initiation factor 3 complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit F

Enables identical protein binding activity and metal-dependent deubiquitinase activity. Contributes to translation initiation factor activity. Involved in IRES-dependent viral translational initiation and translational initiation. Located in membrane. Part of eukaryotic translation initiation factor 3 complex. Implicated in autosomal recessive intellectual developmental disorder 67. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit I pseudogene

eukaryotic translation initiation factor 3, subunit K pseudogene 3

eukaryotic translation initiation factor 4B pseudogene 2

eukaryotic translation initiation factor 4E binding protein 2

This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]

CBP80/20-dependent translation initiation factor

CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009]

eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]

eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa

The protein encoded by this gene is the largest subunit of a heterotrimeric GTP-binding protein involved in the recruitment of methionyl-tRNA(i) to the 40 S ribosomal subunit. [provided by RefSeq, Jan 2010]

eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa

Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

eukaryotic translation initiation factor 1A, X-linked

This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 1A, Y-linked

This gene is located on the non-recombining region of the Y chromosome. It encodes a protein related to eukaryotic translation initiation factor 1A (EIF1A), which may function in stabilizing the binding of the initiator Met-tRNA to 40S ribosomal subunits. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

eukaryotic translation initiation factor 1A domain containing

Predicted to enable RNA binding activity and translation initiation factor activity. Predicted to be involved in translational initiation. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

transcription initiation factor TFIID subunit 4-like

BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit

This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein. [provided by RefSeq, Jul 2008]

BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit

This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]

eukaryotic translation initiation factor 1

Enables ribosomal small subunit binding activity and translation initiation factor activity. Involved in regulation of translational initiation and translational initiation. Located in cytoplasm and nucleus. Part of eukaryotic 43S preinitiation complex; eukaryotic 48S preinitiation complex; and multi-eIF complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 3, subunit L pseudogene 2

eukaryotic translation initiation factor 3, subunit L pseudogene 3

eukaryotic translation initiation factor 3, subunit L pseudogene 1

eukaryotic translation initiation factor 4 gamma, 3

The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]

eukaryotic translation initiation factor 4 gamma, 2

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 4 gamma, 1

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]

eukaryotic translation initiation factor 5

Eukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]

eukaryotic translation initiation factor 6

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

mitochondrial translational initiation factor 2 pseudogene 1

eukaryotic translation initiation factor 5 pseudogene 1

eukaryotic translation initiation factor 5B

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 5A

Enables U6 snRNA binding activity. Involved in several processes, including cellular response to virus; positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and tumor necrosis factor-mediated signaling pathway. Located in annulate lamellae; cytoplasm; and nucleus. Part of nuclear pore. Biomarker of colorectal cancer. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 4E pseudogene 3

eukaryotic translation initiation factor 3, subunit J pseudogene

eukaryotic translation initiation factor 1A, X-linked pseudogene 1

eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa pseudogene

eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa pseudogene

eukaryotic translation initiation factor 5A pseudogene 4

eukaryotic translation initiation factor 5A pseudogene 3

eukaryotic translation initiation factor 5A pseudogene 2

eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa

Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]

eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa

This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. [provided by RefSeq, Aug 2011]

eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa

This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Oct 2009]

eukaryotic translation initiation factor 2-alpha kinase 1

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

eukaryotic translation initiation factor 2-alpha kinase 3

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]

eukaryotic translation initiation factor 2-alpha kinase 2

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021]

eukaryotic translation initiation factor 2 alpha kinase 4

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]

eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa pseudogene

Predicted to enable translation initiation factor activity. Predicted to contribute to tRNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be part of eukaryotic translation initiation factor 2 complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 2D

This gene encodes a translation initiation factor involved in the recruitment and delivery of aminoacyl-tRNAs to the P-site of the eukaryotic ribosome in a GTP-independent manner. This gene was previously referred to as ligatin, but is now known to localize to the cytoplasm and localize and function with translation factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

eukaryotic translation initiation factor 2A, 65kDa

This gene encodes a eukaryotic translation initiation factor that catalyzes the formation of puromycin-sensitive 80 S preinitiation complexes and the poly(U)-directed synthesis of polyphenylalanine at low concentrations of Mg2+. This gene should not be confused with eIF2-alpha (EIF2S1, Gene ID: 1965), the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40 S ribosomal subunit, the encoded protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

eukaryotic translation initiation factor 4A1

Enables double-stranded RNA binding activity and translation initiation factor activity. Involved in cytoplasmic translational initiation and positive regulation of transcription by RNA polymerase II. Located in nuclear stress granule; perinuclear region of cytoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 4A3

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 4A2

Enables ATP hydrolysis activity. Involved in negative regulation of RNA-dependent RNA polymerase activity. Located in perinuclear region of cytoplasm. Implicated in neurodevelopmental disorder with hypotonia and speech delay. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 4E binding protein 1 pseudogene 1

eukaryotic translation initiation factor 4B pseudogene 9

eukaryotic translation initiation factor 4B pseudogene 8

eukaryotic translation initiation factor 4B pseudogene 4

eukaryotic translation initiation factor 4B pseudogene 7

eukaryotic translation initiation factor 4B pseudogene 1

eukaryotic translation initiation factor 4E family member 2 pseudogene 1

eukaryotic translation initiation factor 4E family member 2 pseudogene 2

eukaryotic translation initiation factor 5 pseudogene 2

eukaryotic translation initiation factor 3 subunit J-like

B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 4A1 pseudogene 2

eukaryotic translation initiation factor 4A1 pseudogene 3

eukaryotic translation initiation factor 4A1 pseudogene 1

eukaryotic translation initiation factor 4A1 pseudogene 6

eukaryotic translation initiation factor 4A1 pseudogene 7

eukaryotic translation initiation factor 4A1 pseudogene 4

eukaryotic translation initiation factor 4A1 pseudogene 5

eukaryotic translation initiation factor 4A1 pseudogene 8

eukaryotic translation initiation factor 4A1 pseudogene 9

eukaryotic translation initiation factor 3, subunit I pseudogene 1

mitochondrial translational initiation factor 3 pseudogene

eukaryotic translation initiation factor 3, subunit J pseudogene

eukaryotic translation initiation factor 4A1 pseudogene 10

eukaryotic translation initiation factor 4A1 pseudogene 11

eukaryotic translation initiation factor 4A1 pseudogene 12

eukaryotic translation initiation factor 4A1 pseudogene 13

eukaryotic translation initiation factor 4B pseudogene 5

eukaryotic translation initiation factor 4B pseudogene 6

eukaryotic translation initiation factor 4B pseudogene 3

eukaryotic translation initiation factor 3 subunit A-like

eukaryotic translation initiation factor 3 subunit J-like

RNA polymerase I-specific transcription initiation factor RRN3-like

eukaryotic translation initiation factor 4H

This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

eukaryotic translation initiation factor 4E

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

eukaryotic translation initiation factor 4B

Enables RNA binding activity. Predicted to be involved in regulation of translational initiation. Located in cytosol. Biomarker of autism spectrum disorder and major depressive disorder. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 4E binding protein 1 pseudogene 2

eukaryotic translation initiation factor 2A pseudogene 2

eukaryotic translation initiation factor 2 subunit gamma B

Predicted to enable translation initiation factor activity. Predicted to contribute to tRNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be part of eukaryotic translation initiation factor 2 complex. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic translation initiation factor 1A, X-chromosomal

translation initiation factor IF-2-like

translation initiation factor IF-2-like

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term septation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the cloacal septation biological process from the curated GO Biological Process Annotations 2015 dataset.

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal fetal atrioventricular canal septation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal septation of the cloaca phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal conotruncus septation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

From MPO Gene-Phenotype Associations

gene mutations causing the abnormal truncus arteriosus septation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

From GO Biological Process Annotations 2023

genes participating in the cloacal septation biological process from the curated GO Biological Process Annotations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the abnormal truncus arteriosus septation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the abnormal septation of the cloaca phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the abnormal conotruncus septation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the prenatal lethality prior to heart atrial septation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From IMPC Knockout Mouse Phenotypes

gene knockouts causing the prenatal lethality prior to heart atrial septation phenotype in mic from the IMPC Knockout Mouse Phenotypes dataset.

From GO Biological Process Annotations 2025

genes participating in the cloacal septation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2023

genes participating in the cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration biological process from the curated GO Biological Process Annotations 2023 dataset.

From Biocarta Pathways

proteins participating in the lck and fyn tyrosine kinases in initiation of tcr activation pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells pathway from the Biocarta Pathways dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the translation initiation complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the eukaryotic translation initiation factor 3 complex, eif3m cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the eukaryotic translation initiation factor 2 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the eukaryotic 80s initiation complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the eukaryotic translation initiation factor 2b complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the eukaryotic translation initiation factor 3 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the eukaryotic translation initiation factor 4f complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the translation initiation complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the eukaryotic translation initiation factor 4f complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the eukaryotic translation initiation factor 2b complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the eukaryotic translation initiation factor 3 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the meiotic recombination initiation complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the eukaryotic translation initiation factor 2 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From CORUM Protein Complexes

proteins in the Transcription initiation factor complex (TAF1, TAF5, TAF11, TAF12, TBP) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Transcription initiation factor complex (TAF5, TAF6, TAF9, TAF11, TBP) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Pre-initiation complex (PIC) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the MSH2-MLH1-PMS2 DNA-repair initiation complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the MSH2-MLH1-PMS2-PCNA DNA-repair initiation complex protein complex from the CORUM Protein Complexes dataset.

From CTD Gene-Disease Associations

genes/proteins associated with the disease Sleep Initiation and Maintenance Disorders from the curated CTD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease fatigue; sleep initiation and maintenance disorders in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease sleep initiation and maintenance disorders in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease nicotine dependence; smoking initiation in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease fatigue; sleep disorders; sleep initiation and maintenance disorders in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term initiation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of dna-templated transcription, initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the transcription initiation from rna polymerase iii promoter biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of dna-templated transcription, initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of translational initiation in response to stress biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of translational initiation in response to stress biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of translational initiation in response to stress biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of translational initiation by eif2 alpha phosphorylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the initiation of primordial ovarian follicle growth biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the midbrain-hindbrain boundary initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the transcription initiation from rna polymerase ii promoter biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the transcription initiation from mitochondrial promoter biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of transcription initiation from rna polymerase ii promoter biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of cap-dependent translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of translational initiation by iron biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mitochondrial translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of transcription initiation from rna polymerase ii promoter biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of dna-dependent dna replication initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of transcription initiation from rna polymerase ii promoter biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of dna-templated transcription, initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the initiation of neural tube closure biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of dna-dependent dna replication initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the formation of cytoplasmic translation initiation complex biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the dna-templated transcription, initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of translational initiation by iron biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the dna replication initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the ires-dependent translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the transcription initiation from rna polymerase i promoter biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of translational initiation by iron biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of cap-dependent translational initiation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the translation initiation complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the eukaryotic translation initiation factor 3 complex, eif3m cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the eukaryotic 80s initiation complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the eukaryotic translation initiation factor 2b complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the eukaryotic translation initiation factor 3 complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the eukaryotic translation initiation factor 4f complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the eukaryotic translation initiation factor 2 complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the eukaryotic initiation factor 4g binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the eukaryotic initiation factor eif2 binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the translation initiation factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the eukaryotic translation initiation factor 2alpha kinase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the eukaryotic initiation factor 4e binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the translation initiation factor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Age of smoking initiation phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Smoking initiation phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Cannabis use (initiation) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

From HPO Gene-Disease Associations

genes associated with the impaired pursuit initiation and maintenance phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Sleep Initiation and Maintenance Disorders phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

From HumanCyc Pathways

proteins participating in the fatty acid biosynthesis initiation pathway from the HumanCyc Pathways dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor IIA, gamma subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit G, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation Spt4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor TFIID subunit 1, domain of unknown function protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor, beta propellor-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation Initiation factor eIF- 4e-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit D protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit C, N-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 2, alpha subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor IID, 18kDa subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 3, subunit 12, N-terminal, eukaryotic protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor IF2/IF5, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 1A (eIF-1A), conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 2A protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor TFIID subunit 1, animal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor IIA, gamma subunit, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the RNA polymerase I specific transcription initiation factor RRN3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor SUI1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor TFIIE, beta subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 4E binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 3, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor IIA, gamma subunit, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit E, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor TAFII31 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 3, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor SUI1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 3 complex subunit L protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation Spt4-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor TFIID component TAF4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor IF2/IF5 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 4E (eIF-4E), conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 4E transporter protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Initiation factor eIF-4 gamma, MA3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor Rrn7 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor aIF-2, bacterial-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor IF6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 2, gamma subunit, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Initiation factor 2B alpha/beta/delta protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 2, alpha subunit, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor TFIID protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor TFIID, 23-30kDa subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation Initiation factor eIF- 4e protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit I protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit H protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit K protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit J protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit M protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit A protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit C protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit B protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit E protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit G protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eukaryotic translation initiation factor 3 subunit F protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor IIF, beta subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 1A (eIF-1A) protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription initiation factor IIF, alpha subunit protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor IF2/IF5, zinc-binding protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Fin bud initiation factor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Initiation factor 2B-related protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor 2, alpha subunit, middle domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Translation initiation factor IF- 2, domain 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From MPO Gene-Phenotype Associations

gene mutations causing the failure of initiation of embryo turning phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase I Transcription Initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Telomere C-strand synthesis initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase II Transcription Initiation And Promoter Clearance pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Translation initiation complex formation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Inhibition of replication initiation of damaged DNA by RB1/E2F1 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Cap-dependent Translation Initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Mitochondrial transcription initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the HIV Transcription Initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Mitochondrial translation initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the DNA replication initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase III Abortive And Retractive Initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Eukaryotic Translation Initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase III Transcription Initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase II Transcription Initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the DNA Replication Pre-Initiation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Initiation of Nuclear Envelope Reformation pathway from the Reactome Pathways dataset.

From WikiPathways Pathways 2014

proteins participating in the Eukaryotic Transcription Initiation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Eukaryotic Transcription Initiation(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Sleep Initiation And Maintenance Disorders in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Sleep Initiation Dysfunction in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Tumor Initiation in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Impaired Pursuit Initiation And Maintenance in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of transcription initiation by RNA polymerase II biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the cap-dependent translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of DNA-templated DNA replication initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the transcription initiation-coupled chromatin remodeling biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the transcription initiation at RNA polymerase II promoter biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the formation of cytoplasmic translation initiation complex biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the transcription initiation at mitochondrial promoter biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of transcription initiation by RNA polymerase II biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the DNA replication initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the eukaryotic translation initiation factor 2 complex assembly biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of translational initiation by eIF2 alpha dephosphorylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of cap-dependent translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the transcription initiation at RNA polymerase I promoter biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the mitochondrial translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of eukaryotic translation initiation factor 4F complex assembly biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of translation initiation in response to endoplasmic reticulum stress biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of transcription initiation by RNA polymerase II biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the initiation of neural tube closure biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the transcription initiation at RNA polymerase III promoter biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of translational initiation by iron biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the IRES-dependent translational initiation of linear mRNA biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of translational initiation by eIF2 alpha phosphorylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of translational initiation in response to starvation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of cytoplasmic translational initiation in response to stress biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the mitotic DNA replication initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of translational initiation in response to stress biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of cap-dependent translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of eukaryotic translation initiation factor 4F complex assembly biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of translation initiation in response to endoplasmic reticulum stress biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of translational initiation by iron biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the cap-independent translational initiation of linear mRNA biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of translational initiation in response to starvation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the nuclear cell cycle DNA replication initiation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the translation initiation factor activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the eukaryotic initiation factor 4E binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase III general transcription initiation factor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the general transcription initiation factor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the eukaryotic initiation factor 4G binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase II general transcription initiation factor binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the eukaryotic initiation factor eIF2 binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the eukaryotic translation initiation factor 2alpha kinase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the failure of initiation of embryo turning phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From WikiPathways Pathways 2024

proteins participating in the Initiation of transcription and translation elongation at the HIV 1 LTR pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Eukaryotic transcription initiation pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the nsp1 from SARS CoV 2 inhibits translation initiation in the host cell pathway from the WikiPathways Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Cap-dependent Translation Initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the DNA Replication Pre-Initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the DNA replication initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the EGR2 and SOX10-mediated initiation of Schwann cell myelination pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Eukaryotic Translation Initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the HIV Transcription Initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Inhibition of replication initiation of damaged DNA by RB1/E2F1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Initiation of Nuclear Envelope (NE) Reformation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Mitochondrial transcription initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Mitochondrial translation initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase I Transcription Initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase II Transcription Initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase II Transcription Initiation And Promoter Clearance pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase III Abortive And Retractive Initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase III Transcription Initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase III Transcription Initiation From Type 2 Promoter pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Telomere C-strand synthesis initiation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Translation initiation complex formation pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of transcription initiation by RNA polymerase II biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the cap-dependent translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of DNA-templated DNA replication initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the transcription initiation-coupled chromatin remodeling biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the transcription initiation at RNA polymerase II promoter biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the formation of cytoplasmic translation initiation complex biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the transcription initiation at mitochondrial promoter biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of transcription initiation by RNA polymerase II biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the transcription initiation at RNA polymerase I promoter biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the DNA replication initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of transcription initiation-coupled chromatin remodeling biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the eukaryotic translation initiation factor 2 complex assembly biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of translational initiation in response to stress biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of transcription initiation by RNA polymerase II biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of translation initiation in response to endoplasmic reticulum stress biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of cap-dependent translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the mitochondrial translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of eukaryotic translation initiation factor 4F complex assembly biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of translation initiation in response to endoplasmic reticulum stress biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of translational initiation by tRNA modification biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the initiation of neural tube closure biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the transcription initiation at RNA polymerase III promoter biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of translational initiation by iron biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the IRES-dependent translational initiation of linear mRNA biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of translational initiation by eIF2 alpha phosphorylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of translational initiation in response to starvation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of cytoplasmic translational initiation in response to stress biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the mitotic DNA replication initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the eukaryotic translation initiation factor 4F complex assembly biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of DNA-templated transcription initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of cap-dependent translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of cap-independent translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of cytoplasmic translational initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of eukaryotic translation initiation factor 4F complex assembly biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of translational initiation by iron biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the cap-independent translational initiation of linear mRNA biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of translational initiation in response to starvation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the nuclear cell cycle DNA replication initiation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the eukaryotic initiation factor 4E binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase III general transcription initiation factor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the eukaryotic initiation factor eIF2 binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the general transcription initiation factor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the eukaryotic initiation factor 4G binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase II general transcription initiation factor binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the eukaryotic translation initiation factor 2alpha kinase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Eukaryotic translation initiation factor 3 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Eukaryotic translation initiation factor 2B complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Eukaryotic translation initiation factor 4F complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Eukaryotic translation initiation factor 2 complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Eukaryotic translation initiation factor 3 complex, eIF3m cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the Eukaryotic translation initiation factor 3 complex, eIF3e cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Eukaryotic translation initiation factor 4F complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Eukaryotic translation initiation factor 2B complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Eukaryotic translation initiation factor 3 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Eukaryotic translation initiation factor 2 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Translation initiation complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Meiotic recombination initiation complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Synapsis initiation complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Translation initiation ternary complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Eukaryotic 80S initiation complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From CM4AI U2OS Cell Map Protein Localization Assemblies

proteins comprising Chromatin organization and transcription initiation assembly using integrated AP-MS and IF data from the CM4AI U2OS Cell Map Protein Localization Assemblies dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Cannabis use (initiation) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Smoking initiation (ever regular vs never regular) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Smoking initiation phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the smoking initiation in schizophrenia phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Age at smoking initiation in chronic obstructive pulmonary disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of wnt signaling pathway by bmp signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2023

genes participating in the cell surface receptor signaling pathway involved in cell-cell signaling biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of Wnt signaling pathway by BMP signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From Biocarta Pathways

proteins participating in the calcium signaling by hbx of hepatitis b virus pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the d4gdi signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the igf-1 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tnfr2 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the g-secretase mediated erbb4 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the stat3 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il12 and stat4 dependent signaling pathway in th1 development pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the integrin signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the egf signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the insulin signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the thrombin signaling and protease-activated receptors pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the nitric oxide signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the rac1 cell motility signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the rho cell motility signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the attenuation of gpcr signaling pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the fas signaling pathway (cd95) pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ifn gamma signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il 2 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the chaperones modulate interferon signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the phospholipase c signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il-10 anti-inflammatory signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the pdgf signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tnf/stress related signaling pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the atm signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cell to cell adhesion signaling pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the akt signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tpo signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the t cell receptor signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the bcr signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the mtor signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il 3 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the aspirin blocks signaling pathway involved in platelet activation pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ionomycin and phorbal ester signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il 6 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ras signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the roles of ß arrestin dependent recruitment of src kinases in gpcr signaling pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the bioactive peptide induced signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the p53 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the p38 mapk signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the nf-kb signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the role of mitochondria in apoptotic signaling pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il 4 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the phospholipase c delta in phospholipid associated cell signaling pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ccr3 signaling in eosinophils pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the proteolysis and signaling pathway of notch pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the activation of csk by camp-dependent protein kinase inhibits signaling through the t cell receptor pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the wnt signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il22 soluble receptor signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the erk1/erk2 mapk signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the multiple antiapoptotic pathways from igf-1r signaling lead to bad phosphorylation pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the mapkinase signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the g-protein signaling through tubby proteins pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the fc epsilon receptor i signaling in mast cells pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the apoptotic signaling in response to dna damage pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ceramide signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ifn alpha signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the sodd/tnfr1 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the rb tumor suppressor/checkpoint signaling in response to dna damage pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tnfr1 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the growth hormone signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the epo signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cd40l signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the signaling pathway from g-protein families pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the pertussis toxin-insensitive ccr5 signaling in macrophage pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tgf beta signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cxcr4 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the trka receptor signaling pathway pathway from the Biocarta Pathways dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the death-inducing signaling complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the cd95 death-inducing signaling complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the atg1/ukl1 signaling complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the caveolar macromolecular signaling complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the cd95 death-inducing signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the death-inducing signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the slit-robo signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the hedgehog signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the inad signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the trail death-inducing signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the caveolar macromolecular signaling complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From CORUM Protein Complexes

proteins in the EGFR-containing signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the LAT-PLC-gamma-1-p85-GRB2-SOS signaling complex, C305 activated protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Caveolar macromolecular signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Caveolar macromolecular signaling complex, using anti-Cav-3 protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Tumor necrosis factor receptor 1 signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the PKC-alpha-PLD1-PLC-gamma-2 signaling complex, lacritin stimulated protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Death induced signaling complex DISC (FAS, FADD, CASP8, CFLAR), membrane-associated, CD95L induced protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex (SEC16A, CHUK, IKBKB, NFKB2, REL, IKBKG, MAP3K14, RELA, FBXW7, USP2) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Multicomponent signaling complex, anti-CD40 stimulated,(Birc2, Birc3, Cd40, Ikbkg, Map3k1, Traf2, Ube2n) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the mTOR-signaling complex (FRAP1/mTOR, GBL, RAPTOR) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TRP1-G alpha-11-IP3R3-CAV1 signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex 10 protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the LAT-PLC-gamma-1-p85-GRB2-CBL-VAV-SLP-76 signaling complex, C305 activated protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex (CHUK, BTRC, NFKB2, PPP6C, REL, CUL1, IKBKE, SAPS2, SAPS1, ANKRD28, RELA, SKP1) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Multicomponent signaling complex, anti-CD40 stimulated (Birc2, Birc3, Cd40, Ikbkg, Map2k4, Map2k7, Map3k1, Traf2, Ube2n) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Cytosolic multicomponent signaling complex, anti-CD40 stimulated, (Ikbkg, Map3k1, Traf2, Ube2n) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the BKCA-beta2AR-AKAP79 signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TAJ-NgR1-LINGO-1 signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex 8 protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex 9 protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex 7 protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex 5 protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Death-inducing signaling complex DISC (type I cells associated), stimulated protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the LINGO-1-Nogo-66-p75 signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Death induced signaling complex II (FADD, CASP8, CFLAR), cytosolic, CD95L induced protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the mTOR-signaling complex (mTOR/FRAP1, RAPTOR) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Sam68-p85 P13K-IRS-1-IR signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the mTOR-signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the CFTR-NHERF-beta(2)AR signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Epo-R-PLC-gamma 1-IP(3)R type II-TRPC2 signaling complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the DAP12 signaling homodimer complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Membrane-associated multicomponent signaling complex, anti-CD40 stimulated (Cd40, Ikbkg, Map3k1, Traf2, Ube2n) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex (CHUK, KPNA3, NFKB2, NFKBIB, REL, IKBKG, NFKB1, NFKBIE, RELB, NFKBIA, RELA, TNIP2) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TNF-alpha/NF-kappa B signaling complex 6 protein complex from the CORUM Protein Complexes dataset.

From GAD Gene-Disease Associations

genes associated with the disease platelet signaling in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of lipopolysaccharide-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the smoothened signaling pathway involved in spinal cord motor neuron cell fate specification biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of death-inducing signaling complex assembly biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the collagen-activated tyrosine kinase receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of vitamin d receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of glutamate receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the g-protein coupled receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the adenylate cyclase-inhibiting opioid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the canonical wnt signaling pathway involved in positive regulation of apoptotic process biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of trail-activated apoptotic signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of cd40 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the complement component c5a signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of interferon-gamma-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of toll-like receptor 3 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of macrophage colony-stimulating factor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of toll-like receptor 5 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the phospholipase c-inhibiting g-protein coupled receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of adrenergic receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the vegf-activated platelet-derived growth factor receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of non-canonical wnt signaling pathway via jnk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the platelet-derived growth factor receptor-alpha signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the fc receptor mediated inhibitory signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the cannabinoid signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of vascular endothelial growth factor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of transforming growth factor beta receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the canonical wnt signaling pathway involved in heart development biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the adaptation of rhodopsin mediated signaling biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of myd88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of tor signaling biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the granulocyte colony-stimulating factor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of extrinsic apoptotic signaling pathway via death domain receptors biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the toll-like receptor 8 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the somatostatin receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of interleukin-6-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of interleukin-6-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the vegf-activated neuropilin signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the calcineurin-nfat signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of glucocorticoid receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the canonical wnt signaling pathway involved in positive regulation of wound healing biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of non-canonical wnt signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the lipoprotein particle mediated signaling biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of endothelial cell chemotaxis by vegf-activated vascular endothelial growth factor receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of toll-like receptor 9 signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of branch elongation involved in ureteric bud branching by bmp signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of interferon-gamma-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.