Harmonizome 3.0

From Hub Proteins

Sets of proteins interacting with hub proteins aggregated from data

From Nuclear Receptor Signaling Atlas

Protein-protein interactions inferred from membership in complexes

From Pathway Commons

Protein-protein interactions from low-throughput or high-throughput studies aggregated by Pathway Commons from the following databases: Reactome, NCI Pathways, PhosphoSite, HumanCyc, HPRD, PANTHER, DIP, BioGRID, IntAct, BIND, Transfac, MiRTarBase, Drugbank, Recon X, Comparative Toxicogenomics Database, and KEGG

From Virus MINT

Interactions between viral and human proteins manually curated from literature

From COMPARTMENTS

Protein subcellular localization evidence scores by manual literature curation

From COMPARTMENTS

Protein subcellular localization evidence scores by integrating experimental data

From COMPARTMENTS

Gene-cellular compartment co-occurrence scores from text-mining biomedical abstracts

From CORUM

Proteins participating in complexes by manual literature curation

From Guide to Pharmacology

Protein ligand-receptor interactions curated by experts

From Human Protein Atlas

Semiquantitative protein expression profiles for tissues

From Human Proteome Map

Protein expression profiles for tissues and cell types

From InterPro

Protein domains predicted for gene products based on sequence similarity to known domain signatures

From LOCATE

Subcellular localization of proteins from low-throughput or high-throughput protein localization assays

From Nuclear Receptor Signaling Atlas

Proteins identified in complexes isolated from cultured cells

From Proteomics Database

Protein expression profiles for tissues and cell types reprocessed from many proteomics datasets

From SILAC Phosphoproteomics

Phosphorylation levels of proteins in cell lines following ligand treatment

From TISSUES

Protein tissue expression evidence scores by manual literature curation

From TISSUES

Protein tissue expression evidence scores by integrating experimental data

From TISSUES

Gene-tissue co-occurrence scores from text-mining biomedical abstracts

From Virus MINT

Interactions between viruses and human proteins manually curated from literature

From LOCATE

Subcellular localization of proteins by sequence similarity to localization sequences

From TISSUES

Protein tissue expression evidence scores by manual literature curation

From TISSUES

Protein tissue expression evidence scores by integrating experimental data

From TISSUES

Gene-tissue co-occurrence scores from text-mining biomedical abstracts

From COMPARTMENTS

Protein subcellular localization evidence scores by manual literature curation

From COMPARTMENTS

Protein subcellular localization evidence scores by integrating experimental data

From COMPARTMENTS

Gene-cellular compartment co-occurrence scores from text-mining biomedical abstracts

From Cell Maps for AI

Protein localization assemblies constructed from integrating AP-MS biomolecular interaction and IF imaging data

From Human Protein Atlas

RNA-seq gene expression profiles for cell lines from HPA

From Human Protein Atlas

RNA-seq gene expression profiles for tissues from HPA

From Human Protein Atlas

RNA-seq gene expression profiles for tissue samples from HPA

trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> protein H (aminomethyl carrier) pseudogene

trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> protein H (aminomethyl carrier) pseudogene 2

trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> protein H (aminomethyl carrier) pseudogene

trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> protein H pseudogene 5

trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> protein H (aminomethyl carrier) pseudogene 4

trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> protein H (aminomethyl carrier) pseudogene 3

trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> protein H (aminomethyl carrier)

Degradation of trong>glycinetrong> is brought about by the trong>glycinetrong> trong>cleavagetrong> trong>systemtrong>, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent trong>glycinetrong> decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of trong>glycinetrong> from the P protein to the T protein. Defects in this gene are a cause of nonketotic hypertrong>glycinetrong>mia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.[provided by RefSeq, Jan 2010]

trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> protein H (aminomethyl carrier) pseudogene

trong>glycinetrong> amidinotransferase (L-arginine:trong>glycinetrong> amidinotransferase)

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to trong>glycinetrong>, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:trong>glycinetrong> amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders. [provided by RefSeq, Jul 2008]

trong>cleavagetrong> and polyadenylation specificity factor subunit 5-like

trong>cleavagetrong> and polyadenylation specific factor 3-like

The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

trong>cleavagetrong> and polyadenylation specific factor 4-like

Predicted to enable RNA binding activity and metal ion binding activity. Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of mRNA trong>cleavagetrong> and polyadenylation specificity factor complex. [provided by Alliance of Genome Resources, Mar 2025]

trong>cleavagetrong> and polyadenylation factor I subunit 1

This gene encodes a member of the Clp1 family. The encoded protein is a multifunctional kinase which is a component of the tRNA splicing endonuclease complex and a component of the pre-mRNA trong>cleavagetrong> complex II. This protein is implicated in tRNA, mRNA, and siRNA maturation. Mutations in this gene are associated with pontocerebellar hypoplasia type 10 (PCH10). Alternatively splice transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]

PCF11 trong>cleavagetrong> and polyadenylation factor subunit

The protein encoded by this gene binds to CLP1 to form pre-mRNA trong>cleavagetrong> factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site trong>cleavagetrong>. [provided by RefSeq, Oct 2016]

trong>cleavagetrong> stimulation factor, 3' pre-RNA, subunit 1, 50kDa

This gene encodes one of three subunits which combine to form trong>cleavagetrong> stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end trong>cleavagetrong> of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

trong>cleavagetrong> stimulation factor, 3' pre-RNA, subunit 3, 77kDa

The protein encoded by this gene is one of three (including CSTF1 and CSTF2) trong>cleavagetrong> stimulation factors that combine to form the trong>cleavagetrong> stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end trong>cleavagetrong> of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

trong>cleavagetrong> stimulation factor, 3' pre-RNA, subunit 2, 64kDa

This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the trong>cleavagetrong> stimulation factor (CSTF) complex that is involved in the 3' end trong>cleavagetrong> and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008]

trong>cleavagetrong> and polyadenylation specific factor 7, 59kDa

trong>Cleavagetrong> factor Im (CFIm) is one of six factors necessary for correct trong>cleavagetrong> and polyadenylation of pre-mRNAs. CFIm is composed of three different subunits of 25, 59, and 68 kDa, and it functions as a heterotetramer, with a dimer of the 25 kDa subunit binding to two of the 59 or 68 kDa subunits. The protein encoded by this gene represents the 59 kDa subunit, which can interact with the splicing factor U2 snRNP Auxiliary Factor (U2AF) 65 to link the splicing and polyadenylation complexes. [provided by RefSeq, Oct 2016]

trong>cleavagetrong> and polyadenylation specific factor 6, 68kDa

The protein encoded by this gene is one subunit of a trong>cleavagetrong> factor required for 3' RNA trong>cleavagetrong> and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The trong>cleavagetrong> factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]

trong>cleavagetrong> and polyadenylation specific factor 4, 30kDa

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of trong>cleavagetrong> and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with trong>cleavagetrong> and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end trong>cleavagetrong> and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

trong>cleavagetrong> and polyadenylation specific factor 3, 73kDa

This gene encodes a member of the metallo-beta-lactamase family. The encoded protein is a 73kDa subunit of the trong>cleavagetrong> and polyadenylation specificity factor and functions as an endonuclease that recognizes the pre-mRNA 3'-trong>cleavagetrong> site AAUAAA prior to polyadenylation. It also cleaves after the pre-mRNA sequence ACCCA during histone 3'-end pre-mRNA processing. [provided by RefSeq, Oct 2012]

trong>cleavagetrong> and polyadenylation specific factor 2, 100kDa

Predicted to enable RNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and trong>cleavagetrong>. Located in membrane. Part of mRNA trong>cleavagetrong> and polyadenylation specificity factor complex. [provided by Alliance of Genome Resources, Mar 2025]

trong>cleavagetrong> and polyadenylation specific factor 1, 160kDa

trong>Cleavagetrong> and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA trong>cleavagetrong> and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008]

trong>cleavagetrong> and polyadenylation specific factor 1, 160kDa pseudogene 1

trong>cleavagetrong> stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant

Enables RNA binding activity. Predicted to be involved in mRNA 3'-end processing. Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

trong>cleavagetrong> and polyadenylation specific factor 1, 160kDa pseudogene

solute carrier family 7 (amino acid transporter light chain, y+L trong>systemtrong>), member 6

Enables L-lysine:L-arginine antiporter activity and arginine binding activity. Involved in L-arginine transmembrane transport; L-leucine transport; and ornithine transport. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

solute carrier family 7 (cationic amino acid transporter, y+ trong>systemtrong>), member 1

Enables L-arginine transmembrane transporter activity; L-histidine transmembrane transporter activity; and L-lysine transmembrane transporter activity. Involved in carboxylic acid transport. Located in apical plasma membrane and basolateral plasma membrane. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

limbic trong>systemtrong>-associated membrane protein

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic trong>systemtrong>. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

solute carrier family 7 (amino acid transporter light chain, bo,+ trong>systemtrong>), member 9

This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This protein plays a role in the high-affinity and sodium-independent transport of cystine and neutral and dibasic amino acids, and appears to function in the reabsorption of cystine in the kidney tubule. Mutations in this gene cause non-type I cystinuria, a disease that leads to cystine stones in the urinary trong>systemtrong> due to impaired transport of cystine and dibasic amino acids. Alternate transcript variants, which encode the same protein, have been found for this gene. [provided by RefSeq, Jul 2011]

solute carrier family 7 (amino acid transporter light chain, L trong>systemtrong>), member 8

Enables several functions, including neutral L-amino acid transmembrane transporter activity; protein heterodimerization activity; and secondary active transmembrane transporter activity. Involved in L-alanine import across plasma membrane; L-leucine import across plasma membrane; and thyroid hormone transport. Located in basolateral plasma membrane and microvillus membrane. [provided by Alliance of Genome Resources, Mar 2025]

solute carrier family 7 (amino acid transporter light chain, y+L trong>systemtrong>), member 7

The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]

solute carrier family 7 (amino acid transporter light chain, L trong>systemtrong>), member 5

Enables L-amino acid transmembrane transporter activity and secondary active transmembrane transporter activity. Involved in carboxylic acid transport; thyroid hormone transport; and xenobiotic transport. Located in several cellular components, including apical plasma membrane; cytosol; and microvillus membrane. Part of amino acid transport complex. Implicated in cholangiocarcinoma; colon cancer; hepatocellular carcinoma; and lung squamous cell carcinoma. Biomarker of esophagitis; gastrointestinal trong>systemtrong> cancer (multiple); malignant astrocytoma (multiple); and respiratory trong>systemtrong> cancer (multiple). [provided by Alliance of Genome Resources, Mar 2025]

solute carrier family 7 (cationic amino acid transporter, y+ trong>systemtrong>), member 2

The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

solute carrier family 7 (cationic amino acid transporter, y+ trong>systemtrong>), member 3

This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein.[provided by RefSeq, May 2010]

mitochondrial inner membrane organizing trong>systemtrong> 1 pseudogene 4

solute carrier family 7 (cationic amino acid transporter, y+ trong>systemtrong>), member 3 pseudogene

nervous trong>systemtrong> abundant protein 11

visual trong>systemtrong> homeobox 1

The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

solute carrier family 43 (amino acid trong>systemtrong> L transporter), member 2

This gene encodes a member of the L-amino acid transporter-3 or SLC43 family of transporters. The encoded protein mediates sodium-, chloride-, and pH-independent transport of L-isomers of neutral amino acids, including leucine, phenylalanine, valine and methionine. This protein may contribute to the transfer of amino acids across the placental membrane to the fetus. [provided by RefSeq, Mar 2016]

solute carrier family 43 (amino acid trong>systemtrong> L transporter), member 1

SLC43A1 belongs to the trong>systemtrong> L family of plasma membrane carrier proteins that transports large neutral amino acids (Babu et al., 2003 [PubMed 12930836]).[supplied by OMIM, Mar 2008]

mitochondrial inner membrane organizing trong>systemtrong> 1 pseudogene 3

mitochondrial inner membrane organizing trong>systemtrong> 1 pseudogene 2

mitochondrial inner membrane organizing trong>systemtrong> 1 pseudogene 1

mitochondrial inner membrane organizing trong>systemtrong> 1

Involved in cristae formation. Located in mitochondrion. Part of MIB complex; MICOS complex; and SAM complex. [provided by Alliance of Genome Resources, Mar 2025]

solute carrier family 7 (amino acid transporter light chain, L trong>systemtrong>), member 5 pseudogene 1

This locus represents a pseudogene of the L-type amino acid transporter 1. Transcripts initiating at this locus read through to downstream SMG1 pseudogene 2 (SMG1P2). [provided by RefSeq, Feb 2016]

solute carrier family 7 (amino acid transporter light chain, L trong>systemtrong>), member 5 pseudogene 2

Predicted to enable transmembrane transporter activity. Predicted to be involved in L-alpha-amino acid transmembrane transport. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

solute carrier family 7 (cationic amino acid transporter, y+ trong>systemtrong>), member 3 pseudogene

visual trong>systemtrong> homeobox 2

This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. [provided by RefSeq, Oct 2009]

solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, trong>systemtrong> Xag), member 1

This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]

solute carrier family 7 (neutral amino acid transporter light chain, asc trong>systemtrong>), member 10

SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]

solute carrier family 7 (anionic amino acid transporter light chain, xc- trong>systemtrong>), member 11

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport trong>systemtrong> that is highly specific for cysteine and glutamate. In this trong>systemtrong>, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]

mitochondrial contact site and cristae organizing trong>systemtrong> subunit 10

Involved in cristae formation. Located in mitochondrion. Part of MIB complex; MICOS complex; and SAM complex. [provided by Alliance of Genome Resources, Mar 2025]

mitochondrial contact site and cristae organizing trong>systemtrong> subunit 13

Involved in cristae formation. Located in mitochondrial crista junction and nucleoplasm. Part of MICOS complex. Implicated in combined oxidative phosphorylation deficiency 37. [provided by Alliance of Genome Resources, Mar 2025]

PMS1 homolog 2, mismatch repair trong>systemtrong> component pseudogene 11

Predicted to enable kinase activity. [provided by Alliance of Genome Resources, Mar 2025]

putative trong>glycinetrong>-rich cell wall structural protein 1

trong>glycinetrong>-N-acyltransferase-like 2 pseudogene

cysteine and trong>glycinetrong>-rich protein 2 pseudogene

proline/histidine/trong>glycinetrong>-rich 1

trong>glycinetrong> dehydrogenase (decarboxylating)

Degradation of trong>glycinetrong> is brought about by the trong>glycinetrong> trong>cleavagetrong> trong>systemtrong>, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent trong>glycinetrong> decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to trong>glycinetrong> and enables the methylamine group from trong>glycinetrong> to be transferred to the T protein. Defects in this gene are a cause of nonketotic hypertrong>glycinetrong>mia (NKH).[provided by RefSeq, Jan 2010]

trong>glycinetrong> N-methyltransferase

The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with trong>glycinetrong>) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]

trong>glycinetrong>-N-acyltransferase-like 1 pseudogene 1

trong>glycinetrong> receptor, beta

This gene encodes the beta subunit of the trong>glycinetrong> receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of trong>glycinetrong> to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

trong>glycinetrong>-N-acyltransferase-like 2

Enables trong>glycinetrong> N-acyltransferase activity. Involved in long-chain fatty acid catabolic process; medium-chain fatty acid catabolic process; and monounsaturated fatty acid catabolic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Mar 2025]

trong>glycinetrong>-N-acyltransferase-like 3

Predicted to enable trong>glycinetrong> N-acyltransferase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

trong>glycinetrong>-N-acyltransferase-like 1

Enables glutamine N-acyltransferase activity. Involved in glutamine metabolic process. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

transfer RNA trong>glycinetrong> (anticodon CCC)

This record serves to anchor the annotations of this class of tRNAs at multiple locations on the human genome. The placements are predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).

trong>glycinetrong> dehydrogenase (decarboxylase) pseudogene 1

trong>glycinetrong> receptor, alpha 1

The protein encoded by this gene is a subunit of a pentameric inhibitory trong>glycinetrong> receptor, which mediates postsynaptic inhibition in the central nervous trong>systemtrong>. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found. [provided by RefSeq, Dec 2015]

cysteine and trong>glycinetrong>-rich protein 2 pseudogene

trong>glycinetrong> receptor, alpha 3

This gene encodes a member of the ligand-gated ion channel protein family. The encoded protein is a member of the trong>glycinetrong> receptor subfamily. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

trong>glycinetrong> receptor, alpha 2

The trong>glycinetrong> receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

trong>glycinetrong> receptor, alpha 4

This gene encodes a trong>glycinetrong> receptor and member of the ligand-gated ion channel family of proteins. The encoded protein is missing the fourth transmembrane region compared to related proteins in mouse and rat, and experimental data suggests that the human protein is functionally inactive. However, there is strong evidence to support transcription of this gene. As a result, RefSeq, in collaboration with Ensembl-GENCODE, has determined that this locus is best described as a transcribed pseudogene. [provided by RefSeq, Aug 2019]

transfer RNA trong>glycinetrong> (anticodon UCC)

This record serves to anchor the annotations of this class of tRNAs at multiple locations on the human genome. The placements are predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).

transfer RNA trong>glycinetrong> (anticodon GCC)

This record serves to anchor the annotations of this class of tRNAs at multiple locations on the human genome. The placements are predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).

trong>glycinetrong>-N-acyltransferase

The trong>glycinetrong>-N-acyltransferase protein conjugates trong>glycinetrong> with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

aspartate, trong>glycinetrong>, lysine and serine-rich protein-like

solute carrier family 6 (neurotransmitter transporter, trong>glycinetrong>), member 9

The amino acid trong>glycinetrong> acts as an inhibitory neurotransmitter in the central nervous trong>systemtrong>. The protein encoded by this gene is one of two transporters that stop trong>glycinetrong> signaling by removing it from the synaptic cleft. [provided by RefSeq, Jun 2016]

cysteine and trong>glycinetrong>-rich protein 1

This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]

cysteine and trong>glycinetrong>-rich protein 3 (cardiac LIM protein)

This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

cysteine and trong>glycinetrong>-rich protein 2

CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

trong>glycinetrong>-N-acyltransferase-like 1 pseudogene 2

trong>glycinetrong>-N-acyltransferase-like 1 pseudogene 4

trong>glycinetrong>-N-acyltransferase-like 1 pseudogene 3

Predicted to enable glutamine N-acyltransferase activity. Predicted to be involved in glutamine metabolic process. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

trong>glycinetrong> C-acetyltransferase pseudogene 1

trong>glycinetrong> C-acetyltransferase

The degradation of L-threonine to trong>glycinetrong> consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form trong>glycinetrong> and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14. [provided by RefSeq, Jan 2010]

trong>glycinetrong> B complementing

trong>glycinetrong>-N-acyltransferase pseudogene

DERPC proline and trong>glycinetrong> rich nuclear protein

Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

small cysteine and trong>glycinetrong> repeat containing 4

Predicted to be located in intermediate filament. [provided by Alliance of Genome Resources, Mar 2025]

trong>glycinetrong>-N-acyltransferase like 1B

Predicted to enable glutamine N-acyltransferase activity. Predicted to be involved in glutamine metabolic process. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

trong>glycinetrong> rich extracellular protein 1

small cysteine and trong>glycinetrong> repeat containing 6

Predicted to be located in intermediate filament. [provided by Alliance of Genome Resources, Mar 2025]

small cysteine and trong>glycinetrong> repeat containing 10 (gene/pseudogene)

This gene is a member of a large gene family that encodes keratin associated proteins (KRTAP) that play a role in hair formation. This gene belongs to a subfamily of the KRTAP family termed small cysteine and trong>glycinetrong> repeat containing (SCYGR) genes and it resides in a cluster of SCYGR genes on chromosome 2q36.3. Allelic polymorphisms in this gene result in both coding and non-coding transcripts; the reference genome represents the non-coding allele. [provided by RefSeq, Jan 2024]

small cysteine and trong>glycinetrong> repeat containing 1

small cysteine and trong>glycinetrong> repeat containing 7

small cysteine and trong>glycinetrong> repeat containing 8

small cysteine and trong>glycinetrong> repeat containing 3

small cysteine and trong>glycinetrong> repeat containing 2

small cysteine and trong>glycinetrong> repeat containing 5

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> trong>systemtrong> T protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the trong>glycinetrong> decarboxylation via trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2023

genes participating in the trong>glycinetrong> decarboxylation via trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2025

genes participating in the trong>glycinetrong> decarboxylation via trong>glycinetrong> trong>cleavagetrong> trong>systemtrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GTP-binding protein TrmE/trong>Glycinetrong> trong>cleavagetrong> trong>systemtrong> T protein, domain 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> trong>systemtrong> H-protein, subgroup protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> trong>systemtrong> P-protein, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> trong>systemtrong> H-protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> trong>systemtrong> P protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> trong>systemtrong> P protein, homodimeric protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> T-protein, C-terminal barrel domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> T-protein-like, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Glycinetrong> trong>cleavagetrong> T-protein/YgfZ, C-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the trong>glycinetrong> trong>cleavagetrong> complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the trong>glycinetrong> trong>cleavagetrong> complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From GO Cellular Component Annotations 2015

proteins localized to the trong>glycinetrong> trong>cleavagetrong> complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From HumanCyc Pathways

proteins participating in the trong>glycinetrong> trong>cleavagetrong> pathway from the HumanCyc Pathways dataset.

From GO Cellular Component Annotations 2025

proteins localized to the trong>glycinetrong> trong>cleavagetrong> complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores 2025

proteins localized to the trong>Glycinetrong> trong>cleavagetrong> complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the trong>Glycinetrong> trong>cleavagetrong> complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease trong>Glycinetrong> Encephalopathy With Normal Serum trong>Glycinetrong> in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sterol regulatory element-binding protein trong>cleavagetrong>-activating protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From GO Biological Process Annotations 2025

genes participating in the protein localization to trong>cleavagetrong> furrow biological process from the curated GO Biological Process Annotations 2025 dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical beta-conglycinin protein, trong>Glycinetrong> max from the curated CTD Gene-Chemical Interactions dataset.

From GO Molecular Function Annotations 2015

genes performing the protein-trong>glycinetrong> ligase activity, initiating molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the protein-trong>glycinetrong> ligase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2023

genes performing the protein-trong>glycinetrong> ligase activity, initiating molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the NAD+-protein-C-terminal trong>glycinetrong> ADP-ribosyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2025

genes performing the protein-trong>glycinetrong> ligase activity, initiating molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the G protein-coupled trong>glycinetrong> receptor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the NAD+-protein-C-terminal trong>glycinetrong> ADP-ribosyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GAD Gene-Disease Associations

genes associated with the disease central nervous trong>systemtrong> neoplasms; central nervous trong>systemtrong> tumors; glioma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease alzheimer disease; alzheimer's disease; amyotrophic lateral sclerosis; multiple trong>systemtrong> atrophy; nervous trong>systemtrong> diseases; parkinson disease; polyradiculoneuropathy, chronic inflammatory demyelinating; tauopathies in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease central nervous trong>systemtrong> neoplasms; central nervous trong>systemtrong> tumors; lymphoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cell transformation, neoplastic; central nervous trong>systemtrong> neoplasms; central nervous trong>systemtrong> tumors; lymphoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease central nervous trong>systemtrong> neoplasms; central nervous trong>systemtrong> tumors; hiv infections; lymphoma, aids-related; [x]human immunodeficiency virus disease in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From Reactome Pathways 2024

proteins participating in the Defects of contact activation trong>systemtrong> (CAS) and kallikrein/kinin trong>systemtrong> (KKS) pathway from the Reactome Pathways 2024 dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the trong>cleavagetrong> furrow cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the trong>cleavagetrong> body cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the mrna trong>cleavagetrong> and polyadenylation specificity factor complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Curated Protein Localization Evidence Scores

proteins localized to the mrna trong>cleavagetrong> factor complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mrna trong>cleavagetrong> stimulating factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the trong>cleavagetrong> furrow cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the trong>cleavagetrong> body cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mrna trong>cleavagetrong> and polyadenylation specificity factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores

proteins co-occuring with the mrna trong>cleavagetrong> factor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

From CORUM Protein Complexes

proteins in the CF IIAm complex (trong>Cleavagetrong> factor IIAm complex) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the trong>Cleavagetrong> and polyadenylation factor (CPSF) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the trong>Cleavagetrong> stimulation factor protein complex from the CORUM Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term trong>cleavagetrong> in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the mrna trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the trna splicing, via endonucleolytic trong>cleavagetrong> and ligation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the trna-type intron splice site recognition and trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mrna trong>cleavagetrong> involved in gene silencing by sirna biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the endonucleolytic trong>cleavagetrong> to generate mature 3'-end of ssu-rrna from (ssu-rrna, 5.8s rrna, lsu-rrna) biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mrna trong>cleavagetrong> involved in gene silencing by mirna biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mitochondrial trna 3'-trailer trong>cleavagetrong>, endonucleolytic biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of mrna trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the endonucleolytic trong>cleavagetrong> involved in rrna processing biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the endonucleolytic trong>cleavagetrong> in 5'-ets of tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna) biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the endonucleolytic trong>cleavagetrong> to generate mature 5'-end of ssu-rrna from (ssu-rrna, 5.8s rrna, lsu-rrna) biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of mrna trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the endonucleolytic trong>cleavagetrong> of tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna) biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the trong>cleavagetrong> furrow formation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the trna 3'-trailer trong>cleavagetrong>, endonucleolytic biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the embryonic trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the trong>cleavagetrong> in its2 between 5.8s rrna and lsu-rrna of tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna) biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mrna splicing, via endonucleolytic trong>cleavagetrong> and ligation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the hac1-type intron splice site recognition and trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the trna 3'-trailer trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the rna splicing, via endonucleolytic trong>cleavagetrong> and ligation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the endonucleolytic trong>cleavagetrong> in its1 to separate ssu-rrna from 5.8s rrna and lsu-rrna from tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna) biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the trong>cleavagetrong> furrow ingression biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the trong>cleavagetrong> involved in rrna processing biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the trong>cleavagetrong> furrow cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the trong>cleavagetrong> body cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the mrna trong>cleavagetrong> and polyadenylation specificity factor complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From GO Cellular Component Annotations 2015

proteins localized to the mrna trong>cleavagetrong> factor complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Cleavagetrong> stimulation factor subunit 2, hinge domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pre-mRNA trong>cleavagetrong> complex II Clp1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Cleavagetrong> and polyadenylation specificity factor subunit 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Transcription termination and trong>cleavagetrong> factor C-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Cleavagetrong>/polyadenylation specificity factor, A subunit, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Cleavagetrong> and polyadenylation specificity factor 2, C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the trong>Cleavagetrong>/polyadenylation specificity factor subunit 5 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term trong>cleavagetrong> in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

From Reactome Pathways 2014

proteins participating in the trong>Cleavagetrong> of Growing Transcript in the Termination Region pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the A third proteolytic trong>cleavagetrong> releases NICD pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the trong>Cleavagetrong> of the damaged purine pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the trong>Cleavagetrong> of the damaged pyrimidine pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Apoptotic trong>cleavagetrong> of cellular proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Gamma-carboxylation, transport, and amino-terminal trong>cleavagetrong> of proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Caspase-mediated trong>cleavagetrong> of cytoskeletal proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Activation of caspases through apoptosome-mediated trong>cleavagetrong> pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Apoptotic trong>cleavagetrong> of cell adhesion proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Receptor-ligand binding initiates the second proteolytic trong>cleavagetrong> of Notch receptor pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Caspase-8 activation by trong>cleavagetrong> pathway from the Reactome Pathways dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of mRNA trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the pre-mRNA trong>cleavagetrong> required for polyadenylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the mRNA trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the mRNA splicing, via endonucleolytic trong>cleavagetrong> and ligation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the mRNA trong>cleavagetrong> involved in mRNA processing biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the endonucleolytic trong>cleavagetrong> in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the endonucleolytic trong>cleavagetrong> to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the endonucleolytic trong>cleavagetrong> in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the trong>cleavagetrong> furrow formation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the mitotic trong>cleavagetrong> furrow formation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the mRNA 3'-end processing by stem-loop binding and trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the global gene silencing by mRNA trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tRNA splicing, via endonucleolytic trong>cleavagetrong> and ligation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the endonucleolytic trong>cleavagetrong> of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the mitochondrial tRNA 3'-trailer trong>cleavagetrong>, endonucleolytic biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the trong>cleavagetrong> furrow ingression biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the trong>cleavagetrong> involved in rRNA processing biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the trong>cleavagetrong> in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the endonucleolytic trong>cleavagetrong> involved in tRNA processing biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the endonucleolytic trong>cleavagetrong> to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tRNA-type intron splice site recognition and trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tRNA 3'-trailer trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of mRNA trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the RNA splicing, via endonucleolytic trong>cleavagetrong> and ligation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the endonucleolytic trong>cleavagetrong> involved in rRNA processing biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the tRNA 3'-trailer trong>cleavagetrong>, endonucleolytic biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the co-transcriptional mRNA 3'-end processing, trong>cleavagetrong> and polyadenylation pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Cellular Component Annotations 2023

proteins localized to the mRNA trong>cleavagetrong> and polyadenylation specificity factor complex cellular component from the curated GO Cellular Component Annotations 2023 dataset.

From GO Cellular Component Annotations 2023

proteins localized to the cellularization trong>cleavagetrong> furrow cellular component from the curated GO Cellular Component Annotations 2023 dataset.

From GO Cellular Component Annotations 2023

proteins localized to the mRNA trong>cleavagetrong> stimulating factor complex cellular component from the curated GO Cellular Component Annotations 2023 dataset.

From Reactome Pathways 2024

proteins participating in the Activation of caspases through apoptosome-mediated trong>cleavagetrong> pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Apoptotic trong>cleavagetrong> of cell adhesion proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Apoptotic trong>cleavagetrong> of cellular proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Caspase-mediated trong>cleavagetrong> of cytoskeletal proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the trong>Cleavagetrong> of the damaged purine pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the trong>Cleavagetrong> of the damaged pyrimidine pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Defective F8 trong>cleavagetrong> by thrombin pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Defective VWF trong>cleavagetrong> by ADAMTS13 variant pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Enhanced trong>cleavagetrong> of VWF variant by ADAMTS13 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Gamma-carboxylation, transport, and amino-terminal trong>cleavagetrong> of proteins pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the co-transcriptional mRNA 3'-end processing, trong>cleavagetrong> and polyadenylation pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the mRNA splicing, via endonucleolytic trong>cleavagetrong> and ligation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the endonucleolytic trong>cleavagetrong> in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the endonucleolytic trong>cleavagetrong> to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the endonucleolytic trong>cleavagetrong> in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the trong>cleavagetrong> furrow formation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the mitotic trong>cleavagetrong> furrow formation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the mRNA 3'-end processing by stem-loop binding and trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the co-transcriptional RNA 3'-end processing, trong>cleavagetrong> and polyadenylation pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the global gene silencing by mRNA trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the tRNA splicing, via endonucleolytic trong>cleavagetrong> and ligation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the endonucleolytic trong>cleavagetrong> of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the co-transcriptional lncRNA 3' end processing, trong>cleavagetrong> and polyadenylation pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the trong>cleavagetrong> furrow ingression biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the tRNA-type intron splice site recognition and trong>cleavagetrong> biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the trong>cleavagetrong> in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biological process from the curated GO Biological Process Annotations 2025 dataset.