Harmonizome 3.0

myeloid differentiation primary response 88

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

toll-like receptor 4

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. In silico studies have found a particularly strong binding of surface TLR4 with the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus disease-2019 (COVID-19). This receptor has also been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness, and with susceptibility to age-related macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]

TLR4 interactor with leucine-rich repeats

TRIL is a component of the TLR4 (MIM 603030) complex and is induced in a number of cell types by lipopolysaccharide (LPS) (Carpenter et al., 2009 [PubMed 19710467]).[supplied by OMIM, Apr 2010]

From Reactome Pathways 2024

proteins participating in the MyD88-independent TLR4 cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor 4 (TLR4) Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor 4 (TLR4) Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2014

proteins participating in the MyD88 dependent cascade initiated on endosome pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the MyD88 cascade initiated on plasma membrane pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the MyD88:Mal cascade initiated on plasma membrane pathway from the Reactome Pathways dataset.

From Reactome Pathways 2024

proteins participating in the MyD88 cascade initiated on plasma membrane pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the MyD88 dependent cascade initiated on endosome pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the MyD88:MAL(TIRAP) cascade initiated on plasma membrane pathway from the Reactome Pathways 2024 dataset.

From CORUM Protein Complexes

proteins in the TICAM1-TICAM2-TLR4 complex protein complex from the CORUM Protein Complexes dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tlr4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for TLR4 from the Pathway Commons Protein-Protein Interactions dataset.

From Reactome Pathways 2014

proteins participating in the Activated TLR4 signalling pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the TRIF-mediated TLR3/TLR4 signaling pathway from the Reactome Pathways dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the TLR4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From WikiPathways Pathways 2024

proteins participating in the TLR4 signaling and tolerance pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the LDL influence on CD14 and TLR4 pathway from the WikiPathways Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the TRAF6-mediated induction of TAK1 complex within TLR4 complex pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the TRIF (TICAM1)-mediated TLR4 signaling pathway from the Reactome Pathways 2024 dataset.

From ClinVar Gene-Phenotype Associations

genes associated with the Myd88 deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

From CTD Gene-Disease Associations

genes/proteins associated with the disease MYD88 Deficiency from the curated CTD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term myd88 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of myd88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the myd88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of myd88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Myeloid differentiation primary response protein MyD88 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for MYD88 from the MSigDB Cancer Gene Co-expression Modules dataset.

From OMIM Gene-Disease Associations

genes associated with the pyogenic bacterial infections, recurrent, due to myd88 deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for MYD88 from the Pathway Commons Protein-Protein Interactions dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Myd88 Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From GO Biological Process Annotations 2023

genes participating in the MyD88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of MyD88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of MyD88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the MYD88 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From WikiPathways Pathways 2024

proteins participating in the Toll like receptor signaling related to MyD88 pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the MYD88 distinct input output pathway pathway from the WikiPathways Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the MyD88 deficiency (TLR2/4) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the MyD88 deficiency (TLR5) pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the MyD88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of MyD88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of MyD88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of MyD88-dependent toll-like receptor signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Pyogenic bacterial infections due to MyD88 deficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MYD88 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From Biocarta Pathways

proteins participating in the caspase cascade in apoptosis pathway from the Biocarta Pathways dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores

genes co-occuring with the disease cascade stomach in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cascade in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of non-canonical wnt signaling pathway via jnk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of jak-stat cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of protein activation cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the calcineurin-nfat signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of erk1 and erk2 cascade via tnfsf11-mediated signaling biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of mapkkk cascade by fibroblast growth factor receptor signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of stress-activated mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of jak-stat cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the stress-activated mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of erk1 and erk2 cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of p38mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the non-canonical wnt signaling pathway via jnk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of p38mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of calcineurin-nfat signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of erk1 and erk2 cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the p38mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the jnk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of jnk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of non-canonical wnt signaling pathway via jnk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the kinin cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the epidermal growth factor receptor signaling pathway via i-kappab kinase/nf-kappab cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the erk5 cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of stress-activated mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the modulation by symbiont of host i-kappab kinase/nf-kappab cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the jak-stat cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of protein activation cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of jnk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the activation of blood coagulation via clotting cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the plasma kallikrein-kinin cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of protein activation cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the jak-stat cascade involved in growth hormone signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the protein activation cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of jak-stat cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of calcineurin-nfat signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the non-canonical wnt signaling pathway via mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of calcineurin-nfat signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of erk1 and erk2 cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of jnk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the erk1 and erk2 cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of stress-activated mapk cascade biological process from the curated GO Biological Process Annotations 2015 dataset.

From GWASdb SNP-Phenotype Associations

genes associated with the abnormality of the coagulation cascade phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

From HPO Gene-Disease Associations

genes associated with the abnormality of the coagulation cascade phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

From HumanCyc Pathways

proteins participating in the MAP kinase cascade pathway from the HumanCyc Pathways dataset.

From PANTHER Pathways

proteins participating in the Insulin/IGF pathway-protein kinase B signaling cascade pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Plasminogen activating cascade pathway from the PANTHER Pathways dataset.

From PID Pathways

proteins participating in the Caspase Cascade in Apoptosis pathway from the PID Pathways dataset.

From Reactome Pathways 2014

proteins participating in the MAP kinase activation in TLR cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Inactivation, recovery and regulation of the phototransduction cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the The phototransduction cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the GPVI-mediated activation cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the RAF/MAP kinase cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor 3 (TLR3) Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor TLR6:TLR2 Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Complement cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Formation of Fibrin Clot (Clotting Cascade) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the IGF1R signaling cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Activation of the phototransduction cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Beta-catenin phosphorylation cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the PI-3K cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the FRS2-mediated cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Insulin receptor signalling cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Regulation of Complement cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Phospholipase C-mediated cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor 5 (TLR5) Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the PI3K Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor TLR1:TLR2 Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor 9 (TLR9) Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor 10 (TLR10) Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor 7/8 (TLR7/8) Cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the SHC-mediated cascade pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toll Like Receptor 2 (TLR2) Cascade pathway from the Reactome Pathways dataset.

From WikiPathways Pathways 2014

proteins participating in the Blood Clotting Cascade(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the MAPK Cascade(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Blood Clotting Cascade(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the MAPK Cascade(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From GO Biological Process Annotations 2023

genes participating in the CAMKK-AMPK signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of ERK1 and ERK2 cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of p38MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the p38MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the ERK1 and ERK2 cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of ERK1 and ERK2 cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of JNK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of stress-activated MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of JNK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of ERK1 and ERK2 cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the JNK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the stress-activated MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of p38MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of calcineurin-NFAT signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the calcineurin-NFAT signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of JNK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of stress-activated MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the non-canonical Wnt signaling pathway via JNK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the plasma kallikrein-kinin cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of stress-activated MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the epidermal growth factor receptor signaling pathway via MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of calcineurin-NFAT signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the activation of blood coagulation via clotting cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of p38MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of calcineurin-NFAT signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of CAMKK-AMPK signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the non-canonical Wnt signaling pathway via MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the ERK5 cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of ERK5 cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of non-canonical Wnt signaling pathway via JNK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of CAMKK-AMPK signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the protein activation cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the kinin cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of ERK5 cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of non-canonical Wnt signaling pathway via JNK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

From WikiPathways Pathways 2024

proteins participating in the Blood clotting cascade pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Transcriptional cascade regulating adipogenesis pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the MAPK cascade pathway from the WikiPathways Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Activation of the phototransduction cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Beta-catenin phosphorylation cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Complement cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Diseases associated with the TLR signaling cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Formation of Fibrin Clot (Clotting Cascade) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the GPVI-mediated activation cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the IGF1R signaling cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Inactivation, recovery and regulation of the phototransduction cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Insulin receptor signalling cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the PI-3K cascade:FGFR1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the PI-3K cascade:FGFR2 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the PI-3K cascade:FGFR3 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the PI-3K cascade:FGFR4 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the PI3K Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Phospholipase C-mediated cascade: FGFR1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Phospholipase C-mediated cascade; FGFR2 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Phospholipase C-mediated cascade; FGFR3 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Phospholipase C-mediated cascade; FGFR4 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the RAF/MAP kinase cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Regulation of Complement cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SHC-mediated cascade:FGFR1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SHC-mediated cascade:FGFR2 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SHC-mediated cascade:FGFR3 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SHC-mediated cascade:FGFR4 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the The phototransduction cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor 10 (TLR10) Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor 2 (TLR2) Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor 3 (TLR3) Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor 5 (TLR5) Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor 7/8 (TLR7/8) Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor 9 (TLR9) Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor TLR1:TLR2 Cascade pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toll Like Receptor TLR6:TLR2 Cascade pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the CAMKK-AMPK signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of ERK1 and ERK2 cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of p38MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the p38MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the ERK1 and ERK2 cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of ERK1 and ERK2 cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of JNK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of stress-activated MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of JNK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of ERK1 and ERK2 cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the JNK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the stress-activated MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of p38MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of calcineurin-NFAT signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the calcineurin-NFAT signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of JNK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of stress-activated MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the plasma kallikrein-kinin cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of stress-activated MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of calcineurin-NFAT signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the activation of blood coagulation via clotting cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of p38MAPK cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of calcineurin-NFAT signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of CAMKK-AMPK signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of CAMKK-AMPK signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the ERK5 cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of ERK5 cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of stress-activated protein kinase signaling cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the protein activation cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the kinin cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of protein activation cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of ERK5 cascade biological process from the curated GO Biological Process Annotations 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occuring with the disease Cascade stomach in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.