Harmonizome 3.0

From Pathway Commons

Protein-protein interactions from low-throughput or high-throughput studies aggregated by Pathway Commons from the following databases: Reactome, NCI Pathways, PhosphoSite, HumanCyc, HPRD, PANTHER, DIP, BioGRID, IntAct, BIND, Transfac, MiRTarBase, Drugbank, Recon X, Comparative Toxicogenomics Database, and KEGG

From Pathway Figure Optical Character Recognition

Sets of genes/proteins extracted from pathway figures in research publications using optical character recognition

From Pathway Figure Optical Character Recognition

Sets of genes/proteins extracted from pathway figures in research publications using optical character recognition, updated for 2024

From Pathway Interaction Database

Sets of proteins participating in pathways from PID

ubiquitin fusion degradation 1 like (yeast)

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

ubiquitin fusion degradation 1 like (yeast) pseudogene

ER membrane-associated RNA degradation

The protein encoded by this gene contains 2 transmembrane domains near the C-terminus and is localized in the endoplasmic reticulum. Knockout of this gene in developing rat brain showed that it may be involved in neuronal migration. Mutations in this gene are associated with periventricular nodular heterotopia-6 (PVNH6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

ER degradation enhancer, mannosidase alpha-like 2

In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]

ER degradation enhancer, mannosidase alpha-like 3

Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]

ER degradation enhancer, mannosidase alpha-like 1

Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive regulation of retrograde protein transport, ER to cytosol; protein targeting to ER; and proteolysis involved in protein catabolic process. Located in aggresome and endoplasmic reticulum quality control compartment. [provided by Alliance of Genome Resources, Mar 2025]

ubiquitin recognition factor in ER associated degradation 1

The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18. [provided by RefSeq, Jun 2009]

plakoglobin binding and degradation factor

dickkopf WNT signaling pathway inhibitor 1

This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]

G protein pathway suppressor 1

This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. [provided by RefSeq, Mar 2016]

G protein pathway suppressor 2

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]

epidermal growth factor receptor pathway substrate 15-like 1

Enables cadherin binding activity. Predicted to be involved in endosomal transport and synaptic vesicle endocytosis. Located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

dickkopf WNT signaling pathway inhibitor 4

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2. [provided by RefSeq, Jul 2008]

dickkopf WNT signaling pathway inhibitor 3

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

TOR signaling pathway regulator

TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010]

non-protein coding RNA, associated with MAP kinase pathway and growth arrest

epidermal growth factor receptor pathway substrate 15

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]

dickkopf WNT signaling pathway inhibitor 2

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008]

tumor protein p53 pathway corepressor 1 (non-protein coding)

Predicted to act upstream of or within negative regulation of gene expression. Predicted to be part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Mar 2025]

G protein pathway suppressor 2 pseudogene 1

G protein pathway suppressor 2 pseudogene 2

epidermal growth factor receptor pathway substrate 8

This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

tissue factor pathway inhibitor 2

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

WNT1 inducible signaling pathway protein 2

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover. [provided by RefSeq, Jul 2008]

WNT1 inducible signaling pathway protein 3

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

WNT1 inducible signaling pathway protein 1

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2011]

WNT signaling pathway activating non-coding RNA

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]

epidermal growth factor receptor pathway substrate 15 pseudogene 1

G protein pathway suppressor 1 pseudogene

SREBF pathway regulator in golgi 1

Involved in positive regulation of SREBP signaling pathway. Located in Golgi membrane. [provided by Alliance of Genome Resources, Mar 2025]

non-coding RNA in the aldehyde dehydrogenase 1A pathway

transfer RNA lysine (anticodon CUU)

This record serves to anchor the annotations of this class of tRNAs at multiple locations on the human genome. The placements are predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).

lysine (K)-specific demethylase 1A

This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

lysine (K)-specific demethylase 1B

Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]

K(lysine) acetyltransferase 2B pseudogene

lysine (K)-specific demethylase 3A pseudogene

euchromatic histone-lysine N-methyltransferase 1

The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

euchromatic histone-lysine N-methyltransferase 2

This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008]

splicing regulatory glutamine/lysine-rich protein 1

This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

WNK lysine deficient protein kinase 3

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

lysine (K)-specific demethylase 2A

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

lysine (K)-specific demethylase 2B

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

histone-lysine N-methyltransferase 2C-like

lysine (K)-specific demethylase 4E pseudogene

Predicted to enable histone H3K9 demethylase activity. Predicted to be involved in chromatin remodeling and regulation of gene expression. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

plasminogen receptor, C-terminal lysine transmembrane protein

Predicted to be involved in positive regulation of plasminogen activation. Located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

lysine (K)-specific demethylase 8

This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2009]

lysine (K)-specific demethylase 4E

The protein encoded by this intronless gene is a member of a large family of histone lysine demethylases, which use oxygen and 2-oxoglutarate to demethylate di- and trimethylated lys9 of histone H3. Derepression of genes by demethylases is sometimes involved in viral infection or carcinogenesis, so inhibitors of these enzymes are desired. [provided by RefSeq, Dec 2016]

lysine (K)-specific demethylase 4D

Enables histone H3K9me2/H3K9me3 demethylase activity. Involved in inflammatory response. Acts upstream of or within several processes, including cellular response to ionizing radiation; double-strand break repair via homologous recombination; and positive regulation of double-strand break repair via nonhomologous end joining. Located in site of double-strand break. Biomarker of nephroblastoma. [provided by Alliance of Genome Resources, Mar 2025]

histone-lysine N-methyltransferase SETMAR-like

calmodulin-lysine N-methyltransferase

This gene encodes a class I protein methyltransferase that acts in the formation of trimethyllysine in calmodulin. The protein contains a AdoMet-binding motif and may play a role in calcium-dependent signaling. [provided by RefSeq, Sep 2012]

lysine (K)-specific demethylase 7A

Enables histone demethylase activity; methylated histone binding activity; and transition metal ion binding activity. Predicted to be involved in chromatin remodeling; midbrain development; and regulation of transcription by RNA polymerase II. Located in nucleolus and nucleoplasm. Implicated in melanoma. [provided by Alliance of Genome Resources, Mar 2025]

small lysine-rich protein 1

histone-lysine N-methyltransferase SETMAR-like

lysine-rich coiled-coil 1 pseudogene

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

K(lysine) acetyltransferase 7 pseudogene

WNK lysine deficient protein kinase 4

This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009]

K(lysine) acetyltransferase 2B

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq, Jul 2008]

K(lysine) acetyltransferase 2A

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]

lysine-rich nucleolar protein 1 pseudogene 5

lysine-rich nucleolar protein 1 pseudogene 2

SET domain containing (lysine methyltransferase) 8

The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation. [provided by RefSeq, May 2016]

SET domain containing (lysine methyltransferase) 7

Enables histone H3 methyltransferase activity; p53 binding activity; and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine dimethylation and peptidyl-lysine monomethylation. Acts upstream of or within DNA damage response and heterochromatin organization. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Mar 2025]

lysine (K)-specific demethylase 5D

This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

lysine (K)-specific demethylase 5A

This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. [provided by RefSeq, Aug 2013]

lysine (K)-specific demethylase 5B

This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

lysine (K)-specific demethylase 5C

This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

histone-lysine N-methyltransferase 2C-like

5-phosphohydroxy-L-lysine phospho-lyase

This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

lysine (K)-specific demethylase 4D pseudogene

lysine (K)-specific demethylase 4D pseudogene

K(lysine) acetyltransferase 8

This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

K(lysine) acetyltransferase 5

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

K(lysine) acetyltransferase 7

The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed. [provided by RefSeq, Oct 2016]

lysine (K)-specific demethylase 6A

This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]

lysine (K)-specific demethylase 6B

The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demethylation actvity this gene influences cellular differentiation and development, tumorigenesis, inflammatory diseases, and neurodegenerative diseases. This protein has two classical nuclear localization signals at its N-terminus. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]

WNK lysine deficient protein kinase 2

The protein encoded by this gene is a cytoplasmic serine-threonine kinase that belongs to the protein kinase superfamily. The protein plays an important role in the regulation of electrolyte homeostasis, cell signaling survival, and proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

WNK lysine deficient protein kinase 1

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]

lysine (K)-specific methyltransferase 2C

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]

lysine (K)-specific methyltransferase 2B

This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008]

lysine (K)-specific methyltransferase 2A

This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain, is responsible for its histone H3 lysine 4 (H3K4) methyltransferase activity which mediates chromatin modifications associated with epigenetic transcriptional activation. This protein is processed by the enzyme Taspase 1 into two fragments, MLL-C and MLL-N. These fragments reassociate and further assemble into different multiprotein complexes that regulate the transcription of specific target genes, including many of the HOX genes. Multiple chromosomal translocations involving this gene are the cause of certain acute lymphoid leukemias and acute myeloid leukemias. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2010]

lysine (K)-specific methyltransferase 2E

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

lysine (K)-specific demethylase 5D pseudogene 1

lysine-rich coiled-coil 1

SET domain containing (lysine methyltransferase) 8 pseudogene

histone-lysine N-methyltransferase 2C-like

aspartate, glycine, lysine and serine-rich protein-like

lysine (K)-specific methyltransferase 2D

The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome. [provided by RefSeq, Oct 2010]

valosin containing protein lysine (K) methyltransferase

Enables ATPase binding activity and protein-lysine N-methyltransferase activity. Involved in negative regulation of ATP-dependent activity and peptidyl-lysine trimethylation. Located in cytosol. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

histone-lysine N-methyltransferase SETMAR-like

lysine (K)-specific demethylase 3B

Predicted to enable chromatin DNA binding activity; histone H3K9 demethylase activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. Biomarker of acute lymphoblastic leukemia; breast cancer; colorectal cancer; and lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Mar 2025]

lysine (K)-specific demethylase 3A

Enables histone H3K9me/H3K9me2 demethylase activity; iron ion binding activity; and nuclear androgen receptor binding activity. Involved in androgen receptor signaling pathway; formaldehyde biosynthetic process; and positive regulation of DNA-templated transcription. Located in nucleoplasm. Implicated in cervical cancer and colon cancer. Biomarker of Ewing sarcoma; hepatocellular carcinoma; nasopharynx carcinoma; and prostate cancer. [provided by Alliance of Genome Resources, Mar 2025]

valosin containing protein lysine (K) methyltransferase pseudogene

lysine-rich nucleolar protein 1 pseudogene 4

SET domain containing (lysine methyltransferase) 8 pseudogene

histone-lysine N-methyltransferase SETMAR-like

lysine (K)-specific demethylase 4A

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]

histone-lysine N-methyltransferase SUV39H2-like

lysine-rich nucleolar protein 1 pseudogene 1

lysine-rich nucleolar protein 1 pseudogene 3

histone-lysine N-methyltransferase SETMAR-like

leucine, glutamate and lysine rich 1

lysine (K)-specific demethylase 4D pseudogene

transfer RNA lysine (anticodon UUU)

This record serves to anchor the annotations of this class of tRNAs at multiple locations on the human genome. The placements are predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).

K(lysine) acetyltransferase 6B

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

K(lysine) acetyltransferase 6A

This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]

lysine (K)-specific demethylase 4C

This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

lysine (K)-specific demethylase 4B

Enables histone H3K36 demethylase activity and histone H3K9me2/H3K9me3 demethylase activity. Predicted to be involved in brain development; chromatin remodeling; and regulation of gene expression. Located in cytosol and nucleoplasm. Implicated in autosomal dominant intellectual developmental disorder; breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Biomarker of several diseases, including alopecia areata; lung cancer; medulloblastoma; prostate cancer; and stomach cancer. [provided by Alliance of Genome Resources, Mar 2025]

eukaryotic elongation factor 2 lysine methyltransferase

Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine trimethylation. Located in cytoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

histone-lysine N-methyltransferase 2C

lysine-rich nucleolar protein 1

The protein encoded by this gene is a nucleolar protein that interacts with zinc finger 106 protein. The encoded protein has several of the same characteristics as nucleostemin and may be involved in testis development. [provided by RefSeq, Feb 2017]

MINDY lysine 48 deubiquitinase 3

The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]

MINDY lysine 48 deubiquitinase 1

Enables K48-linked deubiquitinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and cysteine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Located in nuclear body. [provided by Alliance of Genome Resources, Mar 2025]

EEF1A lysine methyltransferase 1

Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

lysine methyltransferase 5C

SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009]

lysine methyltransferase 5A

The protein encoded by this gene is a protein-lysine N-methyltransferase that can monomethylate Lys-20 of histone H4 to effect transcriptional repression of some genes. The encoded protein is required for cell proliferation and plays a role in chromatin condensation. [provided by RefSeq, May 2016]

adenine nucleotide translocase lysine methyltransferase

Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine trimethylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

MINDY lysine 48 deubiquitinase 4

Predicted to enable K48-linked deubiquitinase activity. Predicted to be involved in protein K48-linked deubiquitination and proteolysis. [provided by Alliance of Genome Resources, Mar 2025]

MINDY lysine 48 deubiquitinase 2

Enables peptidase activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in chromatin remodeling and proteolysis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

lysine methyltransferase 5B

This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

ATP synthase c subunit lysine N-methyltransferase

Enables protein-lysine N-methyltransferase activity. Involved in several processes, including peptidyl-lysine trimethylation; positive regulation of proton-transporting ATP synthase activity, rotational mechanism; and positive regulation of sensory perception of pain. Located in mitochondrial crista. [provided by Alliance of Genome Resources, Mar 2025]

lysine acetyltransferase 14

CSRP2 is a protein containing two LIM domains, which are double zinc finger motifs found in proteins of diverse function. CSRP2 and some related proteins are thought to act as protein adapters, bridging two or more proteins to form a larger protein complex. The protein encoded by this gene binds to one of the LIM domains of CSRP2 and contains an acetyltransferase domain. Although the encoded protein has been detected in the cytoplasm, it is predominantly a nuclear protein. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011]

EEF1A lysine methyltransferase 2

Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

EEF1A lysine methyltransferase 4

This gene encodes a member of the lysine-specific methyltransferase (KMT) family. The encoded enzyme catalyzes the methylation of lysine-36 of the eukaryotic translation elongation factor 1 alpha. Methylation by this enzyme may affect endoplasmic reticulum-related processes. [provided by RefSeq, Jul 2017]

EEF1A lysine methyltransferase 3

Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Located in several cellular components, including centrosome; chromosome; and nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

electron transfer flavoprotein subunit beta lysine methyltransferase

Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in mitochondrial matrix. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

citrate synthase lysine methyltransferase

Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine dimethylation; peptidyl-lysine monomethylation; and peptidyl-lysine trimethylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

lysine demethylase 4F

Predicted to enable histone H3K9 demethylase activity. Predicted to be involved in chromatin remodeling and regulation of gene expression. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

HemK methyltransferase 2, ETF1 glutamine and histone H4 lysine

This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Mar 2023]

From HumanCyc Pathways

proteins participating in the lysine degradation II (pipecolate pathway) pathway from the HumanCyc Pathways dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine catabolic process to acetyl-coa via l-pipecolate biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2023

genes participating in the L-lysine catabolic process to acetyl-CoA via L-pipecolate biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-lysine catabolic process to acetyl-CoA via L-pipecolate biological process from the curated GO Biological Process Annotations 2025 dataset.

From HumanCyc Pathways

proteins participating in the lysine degradation I (saccharopine pathway) pathway from the HumanCyc Pathways dataset.

From GO Molecular Function Annotations 2015

genes performing the l-pipecolate oxidase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2023

genes performing the L-pipecolate oxidase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2025

genes performing the L-pipecolate oxidase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From KEGG Pathways

proteins participating in the lysine degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways 2026

proteins participating in the Lysine degradation pathway from the KEGG Pathways 2026 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine hydroxylation to 5-hydroxy-l-lysine biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine biological process from the curated GO Biological Process Annotations 2025 dataset.

From Biocarta Pathways

proteins participating in the er associated degradation (erad) pathway pathway from the Biocarta Pathways dataset.

From HumanCyc Pathways

proteins participating in the D-galactose degradation V (Leloir pathway) pathway from the HumanCyc Pathways dataset.

From WikiPathways Pathways 2024

proteins participating in the Degradation pathway of sphingolipids including diseases pathway from the WikiPathways Pathways 2024 dataset.

From Biocarta Pathways

proteins participating in the degradation of the rar and rxr by the proteasome pathway from the Biocarta Pathways dataset.

From GAD Gene-Disease Associations

genes associated with the disease dna degradation, necrotic in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term degradation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mitochondrion degradation by induced vacuole formation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of mitochondrion degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peroxisome degradation biological process from the curated GO Biological Process Annotations 2015 dataset.

From HuGE Navigator Gene-Phenotype Associations

genes associated with the DNA Degradation, Necrotic phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

From HumanCyc Pathways

proteins participating in the α-tocopherol degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the sorbitol degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation III pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the tryptophan degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation VI pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the melatonin degradation II pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-serine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the alanine biosynthesis/degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the N-acetylglucosamine degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glutaryl-CoA degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the asparagine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the ethanol degradation IV pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the tyrosine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glutamate biosynthesis/degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the superoxide radicals degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the phenylethylamine degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the putrescine degradation III pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the S-methyl-5-thio-α-D-ribose 1-phosphate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 3-phosphoinositide degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the methionine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the trehalose degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the thyroid hormone metabolism II (via conjugation and/or degradation) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the S-methyl-5'-thioadenosine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the tryptophan degradation X (mammalian, via tryptamine) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the lactose degradation III pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the phenylalanine degradation/tyrosine biosynthesis pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-cysteine degradation II pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the ethanol degradation II pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the uracil degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-kynurenine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the threonine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the D-myo-inositol (1,4,5)-trisphosphate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the cysteine biosynthesis/homocysteine degradation (trans-sulfuration) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the superpathway of choline degradation to L-serine pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the serotonin degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the methylglyoxal degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the dermatan sulfate degradation (metazoa) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the guanosine nucleotides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the pyrimidine deoxyribonucleosides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-dopa degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the histamine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 2'-deoxy-α-D-ribose 1-phosphate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the pyrimidine ribonucleosides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the D-mannose degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the purine nucleotides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the noradrenaline and adrenaline degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the superpathway of methionine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 4-aminobutyrate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the anandamide degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glycine betaine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the spermine and spermidine degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glycerol degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the phytol degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the dopamine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the L-cysteine degradation I pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the histidine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the β-alanine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the sucrose degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the urate biosynthesis/inosine 5'-phosphate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the glutamine degradation/glutamate biosynthesis pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the purine deoxyribonucleosides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the oxidative ethanol degradation III pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 4-hydroxyproline degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the triacylglycerol degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the purine ribonucleosides degradation to ribose-1-phosphate pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the heme degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the propionyl-CoA degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the proline degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the 2-oxobutanoate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the chondroitin sulfate degradation (metazoa) pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the D-glucuronate degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the N-acetylglucosamine degradation II pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the adenosine nucleotides degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the thymine degradation pathway from the HumanCyc Pathways dataset.

From HumanCyc Pathways

proteins participating in the choline degradation pathway from the HumanCyc Pathways dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phenylacetic acid degradation-related domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ubiquitin fusion degradation protein UFD1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Vacuolar import/degradation protein Vid24 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From KEGG Pathways

proteins participating in the atrazine degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the 3 chloroacrylic acid degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the 1 and 2 methylnaphthalene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the naphthalene and anthracene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the caprolactam degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the ethylbenzene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the gamma hexachlorocyclohexane degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the limonene and pinene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the bisphenol a degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the 1,4 dichlorobenzene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the benzoate degradation via coa ligation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the tetrachloroethene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the n glycan degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the synthesis and degradation of ketone bodies pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the styrene degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the valine leucine and isoleucine degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the glycosaminoglycan degradation pathway from the KEGG Pathways dataset.

From KEGG Pathways

proteins participating in the glycan structures degradation pathway from the KEGG Pathways dataset.

From PANTHER Pathways

proteins participating in the Ornithine degradation pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Ascorbate degradation pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Phenylethylamine degradation pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Allantoin degradation pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Aminobutyrate degradation pathway from the PANTHER Pathways dataset.

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term degradation in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

From PID Pathways

proteins participating in the Degradation of beta catenin pathway from the PID Pathways dataset.

From Reactome Pathways 2014

proteins participating in the SCF-beta-TrCP mediated degradation of Emi1 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of GABA pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the HS-GAG degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Gap junction degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Ubiquitin-dependent degradation of Cyclin D1 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Hyaluronan uptake and degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Biosynthesis of A2E, implicated in retinal degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Enzymatic degradation of Dopamine by monoamine oxidase pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Enzymatic degradation of dopamine by COMT pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC-Cdc20 mediated degradation of Nek2A pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the degradation of DVL pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Keratan sulfate degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the degradation of AXIN pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the CS/DS degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Regulation of activated PAK-2p34 by proteasome mediated degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of cysteine and homocysteine pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Collagen degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the GABA synthesis, release, reuptake and degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of Securin pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C:Cdc20 mediated degradation of Cyclin B pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the SCF(Skp2)-mediated degradation of p27/p21 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Ubiquitin-dependent degradation of Cyclin D pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Vif-mediated degradation of APOBEC3G pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the APC/C-mediated degradation of cell cycle proteins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Vpu mediated degradation of CD4 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Cdc20:Phospho-APC/C mediated degradation of Cyclin A pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Antigen processing: Ubiquitination & Proteasome degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Heme degradation pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of GLI1 by the proteasome pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Degradation of beta-catenin by the destruction complex pathway from the Reactome Pathways dataset.

From WikiPathways Pathways 2014

proteins participating in the Synthesis and Degradation of Ketone Bodies(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Proteasome Degradation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Proteasome Degradation(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the Synthesis and Degradation of Ketone Bodies(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the PCSK9-mediated LDLR degradation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From GO Biological Process Annotations 2023

genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2023 dataset.

From WikiPathways Pathways 2024

proteins participating in the Proteasome degradation pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the PCSK9 mediated LDL receptor degradation pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Gamma glutamyl cycle for the biosynthesis and degradation of glutathione including diseases pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Glycosaminoglycan degradation pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Glycogen synthesis and degradation pathway from the WikiPathways Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC-Cdc20 mediated degradation of Nek2A pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C-mediated degradation of cell cycle proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of Cyclin B pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of Securin pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Antigen processing: Ubiquitination & Proteasome degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Biosynthesis of A2E, implicated in retinal degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the CS/DS degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Cdc20:Phospho-APC/C mediated degradation of Cyclin A pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Collagen degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of AXIN pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of DVL pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of GABA pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of GLI1 by the proteasome pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of beta-catenin by the destruction complex pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of cysteine and homocysteine pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Degradation of the extracellular matrix pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Enzymatic degradation of Dopamine by monoamine oxidase pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Enzymatic degradation of dopamine by COMT pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the GABA synthesis, release, reuptake and degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Gap junction degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Glycine degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Glyoxylate metabolism and glycine degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the HS-GAG degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Heme degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Hyaluronan uptake and degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Keratan sulfate degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the M-decay: degradation of maternal mRNAs by maternally stored factors pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Mitochondrial RNA degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Mitochondrial protein degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Regulation of TP53 Degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Regulation of TP53 Expression and Degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Regulation of activated PAK-2p34 by proteasome mediated degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SCF(Skp2)-mediated degradation of p27/p21 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the SCF-beta-TrCP mediated degradation of Emi1 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Ubiquitin Mediated Degradation of Phosphorylated Cdc25A pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Ubiquitin-dependent degradation of Cyclin D pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the VLDLR internalisation and degradation pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Vif-mediated degradation of APOBEC3G pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Vpu mediated degradation of CD4 pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Z-decay: degradation of maternal mRNAs by zygotically expressed factors pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the target-directed miRNA degradation biological process from the curated GO Biological Process Annotations 2025 dataset.

From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025

proteins co-occuring with the Ethanolamine degradation polyhedral organelle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

From KEGG Pathways 2026

proteins participating in the Fatty acid degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the Valine, leucine and isoleucine degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the Glycosaminoglycan degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the Other glycan degradation pathway from the KEGG Pathways 2026 dataset.

From KEGG Pathways 2026

proteins participating in the RNA degradation pathway from the KEGG Pathways 2026 dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical aspartyl-alanyl-histidyl-lysine from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical glycyl-histidyl-lysine from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical N6-(((4-(4-aminobenzyl)phenyl)amino)carbonyl)lysine from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical N6-(((4-(4-(acetylamino)benzyl)phenyl)amino)carbonyl)lysine from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical deuterohemin-alanyl-histidyl-threonyl-valyl-glutamyl-lysine from the curated CTD Gene-Chemical Interactions dataset.

From dbGAP Gene-Trait Associations

genes associated with the trait Lysine in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

From DrugBank Drug Targets

interacting proteins for the 4r-Fluoro-N6-Ethanimidoyl-L-Lysine drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the L-Lysine drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the N'-Pyridoxyl-Lysine-5'-Monophosphate drug from the curated DrugBank Drug Targets dataset.

From GAD Gene-Disease Associations

genes associated with the disease lysine in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lysine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine import into cell biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the histone h2b conserved c-terminal lysine ubiquitination biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine trimethylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine n6-acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine modification biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine desuccinylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the lysine transport biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine catabolic process to acetyl-coa biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine catabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine monomethylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine catabolic process to acetyl-coa via saccharopine biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine methylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine transport biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of n-terminal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the lysine import biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the histone lysine methylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the lysine metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine import biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the protein-pyridoxal-5-phosphate linkage via peptidyl-n6-pyridoxal phosphate-l-lysine biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine deacetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the histone h2b conserved c-terminal lysine deubiquitination biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine transmembrane transport biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine dimethylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the isopeptide cross-linking via n6-(l-isoglutamyl)-l-lysine biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine demalonylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine modification to peptidyl-hypusine biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the lysine catabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the n-terminal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of n-terminal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the internal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the histone lysine demethylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine import across plasma membrane biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the peptidyl-lysine hydroxylation biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the l-lysine metabolic process biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the lysine-acetylated histone binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the high-affinity lysine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the calmodulin-lysine n-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the l-lysine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the protein-lysine n-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the lysine n-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the lysine n-acetyltransferase activity, acting on acetyl phosphate as donor molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the peptidyl-lysine n-acetyltransferase activity, acting on acetyl phosphate as donor molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the peptidyl-lysine 5-dioxygenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the lysine-trna ligase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the saccharopine dehydrogenase (nadp+, l-lysine-forming) activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the protein-lysine 6-oxidase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the acetyl-coa:l-lysine n6-acetyltransferase molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the histone-lysine n-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the procollagen-lysine 5-dioxygenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the L-lysine ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the chenodeoxycholyl-N^ε-nitrobenzoxadiazol-lysine ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the beta-Alanyl-L-lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the N(6)-(Octanoyl)lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the N2-Galacturonyl-L-lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the N6-Galacturonyl-L-lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the 5-phosphonooxy-L-lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the L-Lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the N6,N6,N6-Trimethyl-L-lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HMDB Metabolites of Enzymes

interacting proteins for the N6-Acetyl-L-lysine metabolite from the curated HMDB Metabolites of Enzymes dataset.

From HPO Gene-Disease Associations

genes associated with the abnormality of lysine metabolism phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lysine-specific demethylase 6B protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Calmodulin-lysine N-methyltransferase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the N-lysine methyltransferase See1-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histone lysine-specific demethylase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histone-lysine N-methyltransferase, SETD3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histone-lysine N-methyltransferase, SET protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histone-lysine N-methyltransferase, Suvar4-20 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histone-lysine N-methyltransferase SETDB1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the N-lysine methyltransferase SETD6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lysine-tRNA ligase, class II protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histone-lysine N-methyltransferase DOT1 domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lysine-specific demethylase-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Histone-lysine N-methyltransferase Smyd3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Procollagen-lysine 5-dioxygenase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lysine-rich nucleolar protein 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Ribosome receptor lysine/proline rich protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lysine-specific demethylase 6A (UTX) protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From KEGG Pathways

proteins participating in the lysine biosynthesis pathway from the KEGG Pathways dataset.

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term lysine in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

From Reactome Pathways 2014

proteins participating in the Hypusine synthesis from eIF5A-lysine pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Lysine catabolism pathway from the Reactome Pathways dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Lysine Alpha-Ketoglutarate Reductase Deficiency Disease in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Lysine Measurement in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

From GO Biological Process Annotations 2023

genes participating in the lysine catabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine trimethylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine monomethylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine dimethylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine hydroxylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the isopeptide cross-linking via N6-glycyl-L-lysine biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the internal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine oxidation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the lysine transport biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine deacetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine modification biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of N-terminal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the N-terminal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine propionylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine crotonylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine butyrylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine methylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the L-lysine transmembrane transport biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the L-lysine import across plasma membrane biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine glutarylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the histone lysine methylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine deglycation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine demalonylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine desuccinylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the peptidyl-lysine N6-acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of peptidyl-lysine crotonylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the histone H2B conserved C-terminal lysine ubiquitination biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the lysine biosynthetic process via aminoadipic acid biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the lysine metabolic process biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the L-lysine transport biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of N-terminal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the histone lysine demethylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the L-lysine catabolic process to acetyl-CoA biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of peptidyl-lysine crotonylation biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the lysine biosynthetic process biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the lysine N-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the protein-lysine N-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the procollagen-lysine 5-dioxygenase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the lysine-acetylated histone binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the ornithine(lysine) transaminase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the L-lysine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the lysine N-acetyltransferase activity, acting on acetyl phosphate as donor molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the lysine-tRNA ligase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the calmodulin-lysine N-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the NAD+- protein-lysine ADP-ribosyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the high-affinity lysine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the L-lysine:L-arginine antiporter activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the peptidyl-lysine acetyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the saccharopine dehydrogenase (NAD+, L-lysine-forming) activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the saccharopine dehydrogenase (NADP+, L-lysine-forming) activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the increased circulating lysine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the increased lysine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the decreased circulating lysine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the decreased lysine level phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From MW Enzyme Metabolite Associations

interacting proteins for Lysine metabolite from the MW Gene Metabolite Associations dataset.

From MW Enzyme Metabolite Associations

interacting proteins for (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine metabolite from the MW Gene Metabolite Associations dataset.

From Reactome Pathways 2024

proteins participating in the Hypusine synthesis from eIF5A-lysine pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Lysine catabolism pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the lysine catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine trimethylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine monomethylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine dimethylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine hydroxylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the internal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine oxidation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the lysine transport biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine modification to peptidyl-hypusine biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine deacetylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine modification biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the N-terminal peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine propionylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine crotonylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine butyrylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine methylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-lysine transmembrane transport biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-lysine import across plasma membrane biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine glutarylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine demalonylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine desuccinylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the peptidyl-lysine N6-acetylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of peptidyl-lysine crotonylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the lysine biosynthetic process via aminoadipic acid biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the lysine metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-lysine transport biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of peptidyl-lysine acetylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the L-lysine catabolic process to acetyl-CoA biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of peptidyl-lysine crotonylation biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the lysine biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the lysine N-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the protein-lysine N-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the procollagen-lysine 5-dioxygenase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the lysine-acetylated histone binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the L-lysine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the lysine-tRNA ligase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the calmodulin-lysine N-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the NAD-dependent protein lysine deacetylase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the NAD+-protein-lysine ADP-ribosyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the D-lysine 5,6-aminomutase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the high-affinity lysine transmembrane transporter activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the L-lysine:L-arginine antiporter activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the NAD-dependent protein-lysine depropionylase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the NAD-dependent protein lysine delactylase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the saccharopine dehydrogenase (NAD+, L-lysine-forming) activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the saccharopine dehydrogenase (NADP+, L-lysine-forming) activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the LYSINE drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the SELADELPAR LYSINE drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the IBUPROFEN LYSINE drug from theDGIdb Drug Targets 2026 dataset.

From GO Biological Process Annotations 2015

genes participating in the wnt signaling pathway, calcium modulating pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of wnt signaling pathway by bmp signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2015 dataset.

From PANTHER Pathways

proteins participating in the Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway pathway from the PANTHER Pathways dataset.

From PANTHER Pathways

proteins participating in the Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway pathway from the PANTHER Pathways dataset.

From GO Biological Process Annotations 2023

genes participating in the Wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of Wnt signaling pathway, calcium modulating pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of Wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the Wnt signaling pathway, calcium modulating pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of Wnt signaling pathway by BMP signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of Wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of Wnt signaling pathway, calcium modulating pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Biological Process Annotations 2025

genes participating in the Wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of Wnt signaling pathway, calcium modulating pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of Wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the Wnt signaling pathway, calcium modulating pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of Wnt signaling pathway, planar cell polarity pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of Wnt signaling pathway, calcium modulating pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

From Biocarta Pathways

proteins participating in the d4gdi signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the igf-1 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cyclin e destruction pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tnfr2 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the granzyme a mediated apoptosis pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the g-secretase mediated erbb4 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the stat3 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il12 and stat4 dependent signaling pathway in th1 development pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the hop pathway in cardiac development pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the integrin signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the egf signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the role of erk5 in neuronal survival pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the nerve growth factor pathway (ngf) pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the lectin induced complement pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the dicer pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the insulin signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the nitric oxide signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the rac1 cell motility signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cystic fibrosis transmembrane conductance regulator (cftr) and beta 2 adrenergic receptor (b2ar) pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cbl mediated ligand-induced downregulation of egf receptors pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the rho cell motility signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the fas signaling pathway (cd95) pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ifn gamma signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il 2 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the e2f1 destruction pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the chaperones modulate interferon signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the phospholipase c signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il-10 anti-inflammatory signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the pdgf signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the atm signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the akt signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tpo signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the t cell receptor signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ras-independent pathway in nk cell-mediated cytotoxicity pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the bcr signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the mtor signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the no2-dependent il-12 pathway in nk cells pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the b cell survival pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the skeletal muscle hypertrophy is regulated via akt-mtor pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ahr signal transduction pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il 3 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the platelet amyloid precursor protein pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the aspirin blocks signaling pathway involved in platelet activation pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ionomycin and phorbal ester signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the the information processing pathway at the ifn beta enhancer pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il 6 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the classical complement pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the melanocyte development and pigmentation pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ras signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the bioactive peptide induced signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the role of parkin in ubiquitin-proteasomal pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the p53 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cdc25 and chk1 regulatory pathway in response to dna damage pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the intrinsic prothrombin activation pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the p38 mapk signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the extrinsic prothrombin activation pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the nf-kb signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the toll-like receptor pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il 4 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the phospholipase c-epsilon pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the proteolysis and signaling pathway of notch pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the wnt signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the fibrinolysis pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the gamma-aminobutyric acid receptor life cycle pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the il22 soluble receptor signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the erk1/erk2 mapk signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the alternative complement pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the mapkinase signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ceramide signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the ifn alpha signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the sodd/tnfr1 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tnfr1 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the prion pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the growth hormone signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the epo signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the phosphorylation of mek1 by cdk5/p35 down regulates the map kinase pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cd40l signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the antisense pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the signaling pathway from g-protein families pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the tgf beta signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the cxcr4 signaling pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the phosphatidylcholine biosynthesis pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the internal ribosome entry pathway pathway from the Biocarta Pathways dataset.

From Biocarta Pathways

proteins participating in the trka receptor signaling pathway pathway from the Biocarta Pathways dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores

genes co-occuring with the disease visual pathway disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

From GAD Gene-Disease Associations

genes associated with the disease frontal-limbic white matter pathway associations in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease folate pathway vitamin levels in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of lipopolysaccharide-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset.