Name

pexidartinib-resistant FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the pexidartinib-resistant FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of FLT3 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of FLT3 mutants pathway from the Reactome Pathways 2024 dataset.

FLT3 mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling by CBL mutants Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling by CBL mutants pathway from the Reactome Pathways 2024 dataset.

STAT5 activation downstream of FLT3 ITD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the STAT5 activation downstream of FLT3 ITD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FLT3 ITD and TKD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FLT3 ITD and TKD mutants pathway from the Reactome Pathways 2024 dataset.

flt3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term flt3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Flt3 ligand Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Flt3 ligand protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Receptor-type tyrosine-protein kinase FLT3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Receptor-type tyrosine-protein kinase FLT3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

FLT3 Gene Set

From KEA Substrates of Kinases

substrates of the kinase FLT3 from the curated KEA Substrates of Kinases dataset.

FLT3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for FLT3 from the Pathway Commons Protein-Protein Interactions dataset.

FLT3 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase FLT3 from the curated PhosphoSitePlus Substrates of Kinases dataset.

FLT3 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the FLT3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

FLT3 Gene Set

From Kinase Library Tyrosine Kinome Atlas

substrates of the kinase FLT3 from the Kinase Library Tyrosine Kinome Atlas dataset.

FLT3 p Gln640SerfsTer8 signaling Gene Set

From WikiPathways Pathways 2024

proteins participating in the FLT3 p Gln640SerfsTer8 signaling pathway from the WikiPathways Pathways 2024 dataset.

FLT3 Signaling Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 Signaling pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling in disease Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling in disease pathway from the Reactome Pathways 2024 dataset.

FLT3 signaling through SRC family kinases Gene Set

From Reactome Pathways 2024

proteins participating in the FLT3 signaling through SRC family kinases pathway from the Reactome Pathways 2024 dataset.

Negative regulation of FLT3 Gene Set

From Reactome Pathways 2024

proteins participating in the Negative regulation of FLT3 pathway from the Reactome Pathways 2024 dataset.

Signaling by FLT3 fusion proteins Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FLT3 fusion proteins pathway from the Reactome Pathways 2024 dataset.

RECOMBINANT FLT3 LIGAND Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the RECOMBINANT FLT3 LIGAND drug from theDGIdb Drug Targets 2026 dataset.

ANTI-FLT3/CD3 BISPECIFIC ANTIBODY CLN-049 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the ANTI-FLT3/CD3 BISPECIFIC ANTIBODY CLN-049 drug from theDGIdb Drug Targets 2026 dataset.

FLT3 INHIBITOR BMF-500 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 INHIBITOR BMF-500 drug from theDGIdb Drug Targets 2026 dataset.

FLT3 INHIBITOR FF-10101 SUCCINATE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 INHIBITOR FF-10101 SUCCINATE drug from theDGIdb Drug Targets 2026 dataset.

FLT3 TYROSINE KINASE INHIBITOR TTT-3002 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3 TYROSINE KINASE INHIBITOR TTT-3002 drug from theDGIdb Drug Targets 2026 dataset.

FLT3/ABL/AURORA KINASE INHIBITOR KW-2449 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3/ABL/AURORA KINASE INHIBITOR KW-2449 drug from theDGIdb Drug Targets 2026 dataset.

FLT3/CDK4/6 INHIBITOR FLX925 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the FLT3/CDK4/6 INHIBITOR FLX925 drug from theDGIdb Drug Targets 2026 dataset.

Pexidartinib (hydrochloride)_C32 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_HepG2/C3A Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SW 1088 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_A-172 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_LOX-IMVI Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SNU-423 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H1792 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_J82 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SW 900 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_A498 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_BT-474 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_LoVo Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_COLO 205 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_Hs 766T Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SW 1271 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H2122 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_A549 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SW1417 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SK-MEL-2 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H2030 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SW480 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_PANC-1 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_HS-578T Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H596 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_RKO Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H460 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_CFPAC-1 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_HOP62 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_MIA PaCa-2 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_A-427 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_KATO III Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SNU-1 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_HT-29 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_Panc 03.27 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H2347 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SHP-77 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_hTERT-HPNE Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_HEC-1-A Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_CHP-212 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_C-33 A Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_HCT15 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_H4 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_AsPC-1 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H1573 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_AN3 CA Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H661 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_NCI-H23 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_RPMI-7951 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_SW48 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

Pexidartinib (hydrochloride)_LS 180 Gene Set

From Tahoe Therapeutics Tahoe 100M Perturbation Atlas

genes differentially expressed following the Pexidartinib (hydrochloride)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

PEXIDARTINIB Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the PEXIDARTINIB drug from theDGIdb Drug Targets 2026 dataset.

PEXIDARTINIB HYDROCHLORIDE Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the PEXIDARTINIB HYDROCHLORIDE drug from theDGIdb Drug Targets 2026 dataset.

mutants Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mutants in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways dataset.

SMAD2/3 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways dataset.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

AXIN missense mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR3 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR3 mutants pathway from the Reactome Pathways dataset.

APC truncation mutants have impaired AXIN binding Gene Set

From Reactome Pathways 2014

proteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways dataset.

APC truncation mutants are not K63 polyubiquitinated Gene Set

From Reactome Pathways 2014

proteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways dataset.

S37 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S37 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

Signaling by FGFR2 amplification mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways dataset.

S33 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S33 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

FBXW7 Mutants and NOTCH1 in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways dataset.

Signaling by FGFR1 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR1 fusion mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 fusion mutants pathway from the Reactome Pathways dataset.

TCF7L2 mutants don't bind CTBP Gene Set

From Reactome Pathways 2014

proteins participating in the TCF7L2 mutants don't bind CTBP pathway from the Reactome Pathways dataset.

Signaling by FGFR2 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR2 mutants pathway from the Reactome Pathways dataset.

RNF mutants show enhanced WNT signaling and proliferation Gene Set

From Reactome Pathways 2014

proteins participating in the RNF mutants show enhanced WNT signaling and proliferation pathway from the Reactome Pathways dataset.

Signaling by FGFR4 mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR4 mutants pathway from the Reactome Pathways dataset.

Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

truncated APC mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the truncated APC mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

AXIN mutants destabilize the destruction complex, activating WNT signaling Gene Set

From Reactome Pathways 2014

proteins participating in the AXIN mutants destabilize the destruction complex, activating WNT signaling pathway from the Reactome Pathways dataset.

Activated point mutants of FGFR2 Gene Set

From Reactome Pathways 2014

proteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways dataset.

TGFBR2 Kinase Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by FGFR mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR mutants pathway from the Reactome Pathways dataset.

Signaling by FGFR1 amplification mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways dataset.

Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Set

From Reactome Pathways 2014

proteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways dataset.

phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex pathway from the Reactome Pathways dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways dataset.

S45 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the S45 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

T41 mutants of beta-catenin aren't phosphorylated Gene Set

From Reactome Pathways 2014

proteins participating in the T41 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset.

AMER1 mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2014

proteins participating in the AMER1 mutants destabilize the destruction complex pathway from the Reactome Pathways dataset.

misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling Gene Set

From Reactome Pathways 2014

proteins participating in the misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway from the Reactome Pathways dataset.

SMAD4 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset.

TGFBR2 MSI Frameshift Mutants in Cancer Gene Set

From Reactome Pathways 2014

proteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways dataset.

Signaling by activated point mutants of FGFR1 Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways dataset.

Signaling by activated point mutants of FGFR3 Gene Set

From Reactome Pathways 2014

proteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways dataset.

misspliced GSK3beta mutants stabilize beta-catenin Gene Set

From Reactome Pathways 2014

proteins participating in the misspliced GSK3beta mutants stabilize beta-catenin pathway from the Reactome Pathways dataset.

ALK mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the ALK mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

APC truncation mutants are not K63 polyubiquitinated Gene Set

From Reactome Pathways 2024

proteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways 2024 dataset.

APC truncation mutants have impaired AXIN binding Gene Set

From Reactome Pathways 2024

proteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways 2024 dataset.

AXIN missense mutants destabilize the destruction complex Gene Set

From Reactome Pathways 2024

proteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways 2024 dataset.

Activated point mutants of FGFR2 Gene Set

From Reactome Pathways 2024

proteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways 2024 dataset.

CTNNB1 S33 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S33 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

CTNNB1 S37 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S37 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

CTNNB1 S45 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 S45 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

CTNNB1 T41 mutants aren't phosphorylated Gene Set

From Reactome Pathways 2024

proteins participating in the CTNNB1 T41 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset.

Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Gene Set

From Reactome Pathways 2024

proteins participating in the Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) pathway from the Reactome Pathways 2024 dataset.

Defective translocation of RB1 mutants to the nucleus Gene Set

From Reactome Pathways 2024

proteins participating in the Defective translocation of RB1 mutants to the nucleus pathway from the Reactome Pathways 2024 dataset.

Drug resistance in ERBB2 KD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance in ERBB2 KD mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance in ERBB2 TMD/JMD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance in ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of ALK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of ALK mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of KIT mutants pathway from the Reactome Pathways 2024 dataset.

Drug resistance of PDGFR mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Drug resistance of PDGFR mutants pathway from the Reactome Pathways 2024 dataset.

FBXW7 Mutants and NOTCH1 in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways 2024 dataset.

Hh mutants abrogate ligand secretion Gene Set

From Reactome Pathways 2024

proteins participating in the Hh mutants abrogate ligand secretion pathway from the Reactome Pathways 2024 dataset.

Hh mutants are degraded by ERAD Gene Set

From Reactome Pathways 2024

proteins participating in the Hh mutants are degraded by ERAD pathway from the Reactome Pathways 2024 dataset.

KIT mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the KIT mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

PDGFR mutants bind TKIs Gene Set

From Reactome Pathways 2024

proteins participating in the PDGFR mutants bind TKIs pathway from the Reactome Pathways 2024 dataset.

RAS GTPase cycle mutants Gene Set

From Reactome Pathways 2024

proteins participating in the RAS GTPase cycle mutants pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to AEE788 Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to AEE788 pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to afatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to afatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to lapatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to lapatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to neratinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to neratinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to osimertinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to osimertinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to sapitinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to sapitinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to tesevatinib Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to tesevatinib pathway from the Reactome Pathways 2024 dataset.

Resistance of ERBB2 KD mutants to trastuzumab Gene Set

From Reactome Pathways 2024

proteins participating in the Resistance of ERBB2 KD mutants to trastuzumab pathway from the Reactome Pathways 2024 dataset.

SMAD2/3 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

SMAD4 MH2 Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by ALK fusions and activated point mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ALK fusions and activated point mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by AMER1 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by AMER1 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by APC mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by APC mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by AXIN mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by AXIN mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by CTNNB1 phospho-site mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by CTNNB1 phospho-site mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 ECD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 ECD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 KD Mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 KD Mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by ERBB2 TMD/JMD mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FGFR1 amplification mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by FGFR2 amplification mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by GSK3beta mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by GSK3beta mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by LRP5 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by LRP5 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MAP2K mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MAP2K mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MAPK mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MAPK mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by MRAS-complex mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by MRAS-complex mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

Signaling by PDGFRA extracellular domain mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by PDGFRA extracellular domain mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAF1 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAF1 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS GAP mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS GAP mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS GTPase mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS GTPase mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RAS mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RAS mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by RNF43 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by RNF43 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by TCF7L2 mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by TCF7L2 mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by activated point mutants of FGFR1 Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways 2024 dataset.

Signaling by activated point mutants of FGFR3 Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways 2024 dataset.

Signaling by cytosolic FGFR1 fusion mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by cytosolic FGFR1 fusion mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by extracellular domain mutants of KIT Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by extracellular domain mutants of KIT pathway from the Reactome Pathways 2024 dataset.

Signaling by high-kinase activity BRAF mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by high-kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by juxtamembrane domain KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by juxtamembrane domain KIT mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by kinase domain mutants of KIT Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by kinase domain mutants of KIT pathway from the Reactome Pathways 2024 dataset.

Signaling by moderate kinase activity BRAF mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by moderate kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset.

Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants pathway from the Reactome Pathways 2024 dataset.

Signaling downstream of RAS mutants Gene Set

From Reactome Pathways 2024

proteins participating in the Signaling downstream of RAS mutants pathway from the Reactome Pathways 2024 dataset.

TGFBR1 KD Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR1 LBD Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR2 Kinase Domain Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.

TGFBR2 MSI Frameshift Mutants in Cancer Gene Set

From Reactome Pathways 2024

proteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways 2024 dataset.