Harmonizome 3.0

serum response factor (c-fos serum response element-binding transcription factor)

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

ELK3, ETS-domain protein (SRF accessory protein 2)

This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

ELK4, ETS-domain protein (SRF accessory protein 1)

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

RNA, U6 small nuclear variant sequence with SNRPE pseudogene sequence

family with sequence similarity 212, member B

Enables protein kinase binding activity. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 212, member A

Enables protein kinase binding activity and protein serine/threonine kinase inhibitor activity. Predicted to act upstream of or within neural tube development. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 58, member A pseudogene

family with sequence similarity 208, member A pseudogene

family with sequence similarity 210, member B pseudogene

family with sequence similarity 64, member A

Predicted to be involved in cell division. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 92, member A1

Enables phospholipid binding activity. Involved in several processes, including inner mitochondrial membrane organization; limb morphogenesis; and membrane tubulation. Located in several cellular components, including centriole; ciliary base; and mitochondrial crista. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 76, member A pseudogene

family with sequence similarity 71, member A pseudogene

family with sequence similarity 133, member A pseudogene

MHC class I polypeptide-related sequence B pseudogene

MHC class I polypeptide-related sequence B pseudogene

family with sequence similarity 151, member B

Predicted to be involved in photoreceptor cell development. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 151, member A

Located in extracellular exosome. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 64, member A pseudogene

family with sequence similarity 76, member B

Involved in several processes, including mRNA stabilization; negative regulation of macrophage activation; and negative regulation of protein export from nucleus. Located in nuclear speck. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 76, member A

Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 149, member A

family with sequence similarity 172, member A

Predicted to contribute to siRNA binding activity. Predicted to be involved in neural crest cell development; regulation of alternative mRNA splicing, via spliceosome; and regulatory ncRNA-mediated heterochromatin formation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Mar 2025]

signal sequence receptor, gamma (translocon-associated protein gamma) pseudogene

family with sequence similarity 204, member A

family with sequence similarity 102, member B

family with sequence similarity 102, member A

Predicted to be involved in positive regulation of osteoclast differentiation. Predicted to be located in cytoplasm; membrane raft; and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 45, member A

Enables guanyl-nucleotide exchange factor activity and small GTPase binding activity. Involved in endosome transport via multivesicular body sorting pathway; protein transport; and regulation of early endosome to late endosome transport. Located in late endosome. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 45, member A pseudogene

Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in protein transport and regulation of early endosome to late endosome transport. Predicted to be located in endosome. Predicted to be active in late endosome. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 122A

Enables protein phosphatase 2A binding activity and protein serine/threonine phosphatase inhibitor activity. Involved in mitotic G2/M transition checkpoint; positive regulation of cell growth; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in cytoplasm and nuclear body. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 122B

Predicted to enable protein serine/threonine phosphatase inhibitor activity. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 122C

Predicted to enable protein serine/threonine phosphatase inhibitor activity. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 159, member B

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 159, member A

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

family with sequence similarity 196, member B

Predicted to be involved in inhibitory postsynaptic potential. Predicted to be active in postsynaptic density. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 196, member A

Predicted to be involved in inhibitory postsynaptic potential. Predicted to be located in synapse. Predicted to be active in GABA-ergic synapse and postsynaptic density. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 27, member C

family with sequence similarity 27, member B

family with sequence similarity 27-like

family with sequence similarity 58, member A pseudogene

family with sequence similarity 104, member B pseudogene

family with sequence similarity 172, member B pseudogene

Predicted to contribute to siRNA binding activity. Predicted to be involved in regulatory ncRNA-mediated heterochromatin formation. Predicted to be located in membrane. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 188, member A

The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2015]

family with sequence similarity 188, member B

Predicted to enable K48-linked deubiquitinase activity. Predicted to be involved in protein K48-linked deubiquitination and proteolysis. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 115, member C pseudogene

family with sequence similarity 91, member A1 pseudogene

family with sequence similarity 86, member A pseudogene

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

family with sequence similarity 223, member A (non-protein coding)

family with sequence similarity 193, member A

family with sequence similarity 91, member A1

Involved in intracellular protein transport and vesicle tethering to Golgi. Located in cytoplasmic vesicle and trans-Golgi network. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 225, member A (non-protein coding)

family with sequence similarity 225, member B (non-protein coding)

breast carcinoma amplified sequence 2 pseudogene 2

breast carcinoma amplified sequence 2 pseudogene 3

breast carcinoma amplified sequence 2 pseudogene 1

family with sequence similarity 58, member A pseudogene 1

family with sequence similarity 111, member B

This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014]

family with sequence similarity 111, member A

The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

family with sequence similarity 69, member C

This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown. [provided by RefSeq, Nov 2011]

family with sequence similarity 69, member B

This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown. [provided by RefSeq, Nov 2011]

family with sequence similarity 135, member A

family with sequence similarity 135, member B

family with sequence similarity 178, member B pseudogene

family with sequence similarity 168, member B

Predicted to act upstream of or within axonogenesis and gene expression. Located in extracellular exosome. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 166, member B

Predicted to be involved in flagellated sperm motility. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 103, member A1 pseudogene

family with sequence similarity 199, Y-linked, pseudogene

family with sequence similarity 27, member E3

family with sequence similarity 27, member E2

family with sequence similarity 27, member E4

family with sequence similarity 219, member B

family with sequence similarity 219, member A

The protein encoded by this gene has homologs that have been identified in mouse, macaque, etc organisms. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

family with sequence similarity 156, member A pseudogene

family with sequence similarity 90, member A23 pseudogene

neuroblastoma amplified sequence

This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012]

family with sequence similarity 209, member B

Predicted to be involved in acrosome assembly. Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 209, member A

Predicted to be involved in cell differentiation and spermatogenesis. Located in extracellular exosome and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 207, member B, pseudogene

family with sequence similarity 96, member B

Involved in chromosome segregation; iron-sulfur cluster assembly; and protein maturation by iron-sulfur cluster transfer. Located in cytosol; nucleoplasm; and spindle. Part of MMXD complex and cytosolic [4Fe-4S] assembly targeting complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 101, member B

Enables filamin binding activity. Predicted to be involved in several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Predicted to act upstream of or within actin cytoskeleton organization and epithelial to mesenchymal transition. Predicted to be located in actin cytoskeleton and cytoplasm. Predicted to be active in actin filament bundle. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 101, member A

Predicted to enable filamin binding activity. Predicted to be involved in several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in actin filament bundle. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 8, member A1 pseudogene

signal sequence receptor, alpha

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

signal sequence receptor, beta (translocon-associated protein beta)

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008]

signal sequence receptor, gamma (translocon-associated protein gamma)

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times. [provided by RefSeq, Aug 2010]

signal sequence receptor, delta

This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]

family with sequence similarity 193, member B

Located in cytoplasm; nuclear speck; and nucleolus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 20, member A

This locus encodes a protein that is likely secreted and may function in hematopoiesis. A mutation at this locus has been associated with amelogenesis imperfecta and gingival hyperplasia syndrome. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Aug 2011]

family with sequence similarity 20, member B

Enables phosphotransferase activity, alcohol group as acceptor. Predicted to be involved in proteoglycan biosynthetic process. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 20, member C

This gene encodes a member of the family of secreted protein kinases. The encoded protein binds calcium and phosphorylates proteins involved in bone mineralization. Mutations in this gene are associated with the autosomal recessive disorder Raine syndrome. [provided by RefSeq, Apr 2014]

family with sequence similarity 58, member A

Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

family with sequence similarity 177, member B

family with sequence similarity 87, member B

family with sequence similarity 87, member A

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 74, member A4

family with sequence similarity 74, member A6

family with sequence similarity 74, member A1

family with sequence similarity 74, member A3

family with sequence similarity 201, member B

family with sequence similarity 201, member A

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

family with sequence similarity 109, member B

Enables protein homodimerization activity. Involved in endosome organization; receptor recycling; and retrograde transport, endosome to Golgi. Located in cytoplasmic vesicle and trans-Golgi network. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 109, member A

This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

malignant T cell amplified sequence 1

Enables RNA cap binding activity; ribosomal small subunit binding activity; and translation factor activity, non-nucleic acid binding. Involved in IRES-dependent viral translational initiation; cytoplasmic translational initiation; and ribosome disassembly. Is active in cytoplasm. Implicated in primary immunodeficiency disease. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 86, member K, pseudogene

family with sequence similarity 163, member B

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 163, member A

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

malignant fibrous histiocytoma amplified sequence 1

Identified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH. [provided by RefSeq, Jul 2008]

family with sequence similarity 222, member A

family with sequence similarity 222, member B

Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 160, member A2

The protein encoded by this gene is part of the FTS/Hook/FHIP (FHF) complex, which can interact with members of the homotypic vesicular protein sorting (HOPS) complex. This interaction suggests that the encoded protein is involved in vesicle trafficking. [provided by RefSeq, Dec 2016]

family with sequence similarity 50, member B

This gene contains an intronless ORF that arose from ancestral retroposition. The encoded protein is related to a plant protein that plays a role in the circadian clock. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and paternally expressed in many tissues. [provided by RefSeq, Nov 2015]

family with sequence similarity 50, member A

This gene belongs to the FAM50 family. The encoded protein is highly conserved in length and sequence across different species. It is a basic protein containing a nuclear localization signal, and may function as a DNA-binding protein or a transcriptional factor. [provided by RefSeq, Sep 2009]

DNA segment on chromosome 6 (unique, pseudogene) 2723 expressed sequence

family with sequence similarity 133, member A pseudogene

family with sequence similarity 90, member A6 pseudogene

family with sequence similarity 187, member A

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

DYZ1 repeat sequence

DYZ1 repeat sequence

family with sequence similarity 86, member C1

Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 136, member A pseudogene

family with sequence similarity 138, member D

family with sequence similarity 8, member A1

Predicted to be involved in ERAD pathway. Part of Hrd1p ubiquitin ligase complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 188, member B2

Predicted to enable K48-linked deubiquitinase activity. Predicted to be involved in protein K48-linked deubiquitination. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 157, member A

family with sequence similarity 157, member B

family with sequence similarity 157, member C

family with sequence similarity 230, member B (non-protein coding)

family with sequence similarity 214, member A

Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 214, member B

Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 64, member A pseudogene

family with sequence similarity 230, member C

family with sequence similarity 230, member A

family with sequence similarity 182, member A

family with sequence similarity 132, member A

Predicted to enable hormone activity. Predicted to be involved in negative regulation of gluconeogenesis; positive regulation of D-glucose import; and positive regulation of insulin receptor signaling pathway. Predicted to act upstream of or within negative regulation of inflammatory response; positive regulation of cell communication; and regulation of glucose metabolic process. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 132, member B

Predicted to enable hormone activity. Predicted to be involved in several processes, including negative regulation of metabolic process; negative regulation of osteoblast differentiation; and positive regulation of signal transduction. Predicted to act upstream of or within positive regulation of fatty acid transport and regulation of fatty acid metabolic process. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 104, member A

family with sequence similarity 104, member B

family with sequence similarity 197, Y-linked, member 2, pseudogene

family with sequence similarity 197, Y-linked, member 1

family with sequence similarity 197, Y-linked, member 5, pseudogene

family with sequence similarity 197, Y-linked, member 8

family with sequence similarity 197, Y-linked, member 9

family with sequence similarity 60, member A pseudogene

glioblastoma amplified sequence

This gene encodes a member of the NipSnap family of proteins that may be involved in vesicular transport. The encoded protein is localized to mitochondria and plays a role in oxidative phosphorylation. A pseudogene of this gene is located on the long arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

family with sequence similarity 71, member A pseudogene

family with sequence similarity 49, member B pseudogene

CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]

family with sequence similarity 78, member B

family with sequence similarity 174, member B

Involved in Golgi organization. Located in Golgi apparatus and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 90, member A24 (pseudogene)

family with sequence similarity 84, member B

Located in cytoplasm and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 84, member A

Involved in cell morphogenesis and cell motility. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

MCF.2 cell line derived transforming sequence

The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.[provided by RefSeq, Jan 2010]

family with sequence similarity 86, member A pseudogene

family with sequence similarity 47, member C

This gene encodes a product belonging to a family of proteins with unknown function. The coding sequence of this family member includes several tandemly repeated regions. [provided by RefSeq, Sep 2011]

family with sequence similarity 47, member B

family with sequence similarity 47, member E

Enables enzyme activator activity. Involved in protein localization to chromatin and transcription initiation-coupled chromatin remodeling. Located in chromatin; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 120B

Predicted to be involved in fat cell differentiation and peroxisome proliferator activated receptor signaling pathway. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 120C

This gene encodes a potential transmembrane protein and lies in a region where mutations and deletions have been associated with intellectual disability and autism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

family with sequence similarity 120A

Enables RNA binding activity. Located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 41, member A, Y-linked 1

family with sequence similarity 41, member A, Y-linked 2

family with sequence similarity 25, member C

family with sequence similarity 25, member A

family with sequence similarity 25, member G

family with sequence similarity 25, member E

family with sequence similarity 25, member D

family with sequence similarity 133, member A pseudogene

family with sequence similarity 183, member C, pseudogene

family with sequence similarity 53, member B

Involved in positive regulation of canonical Wnt signaling pathway. Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 53, member C

The protein encoded by this gene belongs to the FAM53 protein family. FAM53 protein family members bind to a transcriptional regulator that modulates cell proliferation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]

family with sequence similarity 53, member A

Predicted to be involved in protein import into nucleus. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

signal sequence receptor, delta pseudogene 1

family with sequence similarity 35, member A

Involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Located in actin cytoskeleton; nucleoplasm; and site of double-strand break. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 86, member D, pseudogene

family with sequence similarity 166, member A

Predicted to be involved in flagellated sperm motility. Located in ciliary basal body. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 96, member A

Predicted to enable metal ion binding activity. Involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Located in cytosol and nucleoplasm. Part of cytosolic [4Fe-4S] assembly targeting complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 227, member B

family with sequence similarity 227, member A

breast carcinoma amplified sequence 4

Predicted to be located in cytoplasm. Predicted to be part of BLOC-1 complex. [provided by Alliance of Genome Resources, Mar 2025]

breast carcinoma amplified sequence 2

Involved in mRNA splicing, via spliceosome. Located in DNA replication factor A complex; centrosome; and nuclear speck. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Implicated in breast cancer. [provided by Alliance of Genome Resources, Mar 2025]

breast carcinoma amplified sequence 3

Enables several functions, including acetyltransferase activator activity; beta-tubulin binding activity; and histone acetyltransferase binding activity. Involved in cellular response to estrogen stimulus; positive regulation of catalytic activity; and positive regulation of transcription by RNA polymerase II. Located in euchromatin; nucleus; and phagophore assembly site. Implicated in Hengel-Maroofian-Schols syndrome. Biomarker of breast cancer. [provided by Alliance of Genome Resources, Mar 2025]

breast carcinoma amplified sequence 1

This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. [provided by RefSeq, Apr 2016]

family with sequence similarity 213, member A

Enables antioxidant activity. Involved in regulation of osteoclast differentiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 213, member B

Predicted to enable prostaglandin F synthase activity. Predicted to be involved in prostaglandin biosynthetic process. Located in extracellular exosome and mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011]

family with sequence similarity 19 (chemokine (C-C motif)-like), member A5

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells. [provided by RefSeq, Sep 2013]

family with sequence similarity 19 (chemokine (C-C motif)-like), member A2

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]

family with sequence similarity 19 (chemokine (C-C motif)-like), member A3

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

family with sequence similarity 19 (chemokine (C-C motif)-like), member A1

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]

family with sequence similarity 47, member D (pseudogene)

family with sequence similarity 133, member A pseudogene

family with sequence similarity 182, member B

family with sequence similarity 90, member A3, pseudogene

FAM90A3 belongs to subfamily II of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]). For background information on the FAM90A gene family, as well as information on the evolution of FAM90A genes, see FAM90A1 (MIM 613041).[supplied by OMIM, Oct 2009]

family with sequence similarity 185, member A pseudogene

family with sequence similarity 117, member A

family with sequence similarity 117, member B

family with sequence similarity 114, member A1

The protein encoded by this gene belongs to the FAM114 family and may play a role in neuronal cell development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]

family with sequence similarity 114, member A2

Predicted to enable purine nucleotide binding activity. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 64, member A pseudogene

G-rich RNA sequence binding factor 1

The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

family with sequence similarity 151, member A pseudogene

MHC class I polypeptide-related sequence B pseudogene

family with sequence similarity 150, member A

Enables protein tyrosine kinase activator activity and signaling receptor binding activity. Involved in cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of MAPK cascade; and positive regulation of neuron projection development. Is active in extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 150, member B

Enables protein tyrosine kinase activator activity and signaling receptor binding activity. Involved in cell surface receptor protein tyrosine kinase signaling pathway; positive regulation of MAPK cascade; and positive regulation of neuron projection development. Is active in extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 96, member A pseudogene 2

family with sequence similarity 171, member B

Predicted to be located in membrane. Predicted to be active in synapse. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 90, member A21 pseudogene

DYZ1 repeat sequence

DYZ1 repeat sequence

family with sequence similarity 207, member A

Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome and preribosome, small subunit precursor. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 8, member A1 pseudogene

signal sequence receptor, alpha pseudogene 1

family with sequence similarity 199, X-linked

family with sequence similarity 21, member F, pseudogene

family with sequence similarity 26, member F

Predicted to enable monoatomic cation channel activity. Predicted to be involved in ATP export; monoatomic cation transmembrane transport; and regulation of natural killer cell cytokine production. Predicted to be located in immunological synapse. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 26, member D

Predicted to enable monoatomic cation channel activity. Predicted to be involved in ATP export and monoatomic cation transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 26, member E

Predicted to enable monoatomic cation channel activity. Predicted to be involved in ATP export and monoatomic cation transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

testis expressed sequence 13-like

Predicted to enable mRNA binding activity. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 179, member A

Predicted to enable microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization. Predicted to be located in microtubule cytoskeleton. Predicted to be active in cilium and cytoplasmic microtubule. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 179, member B

Predicted to enable microtubule binding activity. Involved in cilium assembly. Located in axoneme. Implicated in Joubert syndrome. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 189, member B

This gene is located near the gene for the lysosomal enzyme glucosylceramidase; a deficiency in this enzyme is associated with Gaucher disease. The encoded protein has been identified as a potential binding partner of a WW domain-containing protein which is involved in apoptosis and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]

MHC class I polypeptide-related sequence G (pseudogene)

MHC class I polypeptide-related sequence F (pseudogene)

MHC class I polypeptide-related sequence E (pseudogene)

MHC class I polypeptide-related sequence D (pseudogene)

MHC class I polypeptide-related sequence C (pseudogene)

MHC class I polypeptide-related sequence B

This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

MHC class I polypeptide-related sequence A

This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]

family with sequence similarity 81, member A

Predicted to enable molecular condensate scaffold activity. Predicted to be located in postsynaptic density. Predicted to be active in glutamatergic synapse and postsynaptic density, intracellular component. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 81, member B

Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 133, member A pseudogene

family with sequence similarity 71, member B pseudogene

family with sequence similarity 91, member A3 pseudogene

family with sequence similarity 161, member A

This gene belongs to the FAM161 family. It is expressed mainly in the retina. Mouse studies suggested that this gene is involved in development of retinal progenitors during embryogenesis, and that its activity is restricted to mature photoreceptors after birth. Mutations in this gene cause autosomal recessive retinitis pigmentosa-28. Alternatively spliced transcript variants have been identified.[provided by RefSeq, Jan 2011]

family with sequence similarity 161, member B

Predicted to be involved in cilium organization. Located in cytoplasmic microtubule. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 60, member A pseudogene

family with sequence similarity 175, member B

Enables microtubule binding activity and polyubiquitin modification-dependent protein binding activity. Involved in nuclear chromosome segregation; protein K63-linked deubiquitination; and response to ischemia. Located in cytoplasm; microtubule cytoskeleton; and midbody. Part of BRISC complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 98, member B pseudogene

family with sequence similarity 99, member A (non-protein coding)

family with sequence similarity 99, member B (non-protein coding)

family with sequence similarity 197, Y-linked, member 10

malignant T cell amplified sequence 2, pseudogene

This locus represents a retrogene copy of MCTS1 (GeneID:28985) and contains an ORF similar to that parent gene. This locus is situated in a differentially methylated region (DMR) and transcripts in this region are imprinted. [provided by RefSeq, Nov 2021]

family with sequence similarity 224, member B (non-protein coding)

This locus is transcribed but does not appear to encode a protein. Two identical copies of this gene are present in a palindromic region on chromosome Y. This record represents the more centromeric copy. [provided by RefSeq, Jul 2008]

family with sequence similarity 224, member A (non-protein coding)

This locus is transcribed but does not appear to encode a protein. Two identical copies of this gene are present in a palindromic region on chromosome Y. This record represents the more telomeric copy. [provided by RefSeq, Jul 2008]

family with sequence similarity 9, member B

This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be localized to the nucleus as the protein contains several nuclear localization signals, and has similarity to a synaptonemal complex protein. [provided by RefSeq, Aug 2011]

family with sequence similarity 9, member C

This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be localized to the nucleus as the protein contains several nuclear localization signals, and has similarity to a synaptonemal complex protein. [provided by RefSeq, Aug 2011]

family with sequence similarity 9, member A

This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be a nuclear protein that is localized to the nucleolus, and has some similarity to a synaptonemal complex protein. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]

family with sequence similarity 183, member D, pseudogene

family with sequence similarity 35, member A2 (pseudogene)

family with sequence similarity 181, member B

family with sequence similarity 181, member A

Located in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 110, member A

Involved in mitotic spindle organization. Located in cytosol; microtubule cytoskeleton; and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 110, member C

Enables alpha-tubulin binding activity. Involved in positive regulation of cell migration; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and regulation of cell projection assembly. Located in cell cortex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 110, member B

Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 110, member D

family with sequence similarity 169, member A

Predicted to be located in nuclear inner membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 169, member B

family with sequence similarity 134, member C

Predicted to enable endoplasmic reticulum-autophagosome adaptor activity. Involved in endoplasmic reticulum tubular network organization; positive regulation of neuron projection development; and reticulophagy. Located in endoplasmic reticulum tubular network. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 134, member B

The protein encoded by this gene is a cis-Golgi transmembrane protein that may be necessary for the long-term survival of nociceptive and autonomic ganglion neurons. Mutations in this gene are a cause of hereditary sensory and autonomic neuropathy type IIB (HSAN IIB), and this gene may also play a role in susceptibility to vascular dementia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

family with sequence similarity 134, member A

Predicted to enable endoplasmic reticulum-autophagosome adaptor activity. Predicted to be involved in autophagy. Predicted to act upstream of or within collagen catabolic process; endoplasmic reticulum organization; and reticulophagy. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 71, member F1

Predicted to be involved in acrosome assembly and acrosome reaction. Predicted to be located in Golgi apparatus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 71, member F2

Predicted to be involved in acrosome assembly. Predicted to be located in Golgi apparatus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 90, member A17, pseudogene

family with sequence similarity 49, member A

Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 49, member B

Enables small GTPase binding activity. Involved in several processes, including cellular response to molecule of bacterial origin; negative regulation of small GTPase mediated signal transduction; and regulation of organelle organization. Located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 155, member B

This gene encodes a product belonging to a family of proteins with unknown function. The presence of two transmembrane domains suggests that this protein is a multi-pass membrane protein. [provided by RefSeq, Sep 2011]

family with sequence similarity 155, member A

Predicted to contribute to stretch-activated, monoatomic cation-selective, calcium channel activity. Predicted to be involved in calcium ion import across plasma membrane. Located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 216, member B

family with sequence similarity 216, member A

family with sequence similarity 189, member A2

Enables ubiquitin ligase activator activity. Involved in CXCL12-activated CXCR4 signaling pathway and negative adaptation of signaling pathway. Located in endosome membrane and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 189, member A1

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 90, member A22 pseudogene

family with sequence similarity 60, member A

Involved in negative regulation of cell migration. Part of Sin3-type complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 208, member A

Enables chromatin binding activity. Involved in protein localization to heterochromatin and transposable element silencing by heterochromatin formation. Located in heterochromatin and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 208, member B

Predicted to be involved in negative regulation of gene expression, epigenetic. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 207, member C, pseudogene

family with sequence similarity 106, member B

family with sequence similarity 106, member A

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 66, member A

family with sequence similarity 89, member A

family with sequence similarity 89, member B

Predicted to enable transcription corepressor binding activity. Predicted to be involved in establishment of cell polarity; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and positive regulation of cell migration. Predicted to be located in cell projection. Predicted to be active in cytoplasm and lamellipodium. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 41, member C

family with sequence similarity 126, member A

The protein encoded by this gene may play a part in the beta-catenin/Lef signaling pathway. Expression of this gene is down-regulated by beta-catenin. Defects in this gene are a cause of hypomyelination with congenital cataract (HCC). [provided by RefSeq, Oct 2008]

family with sequence similarity 126, member B

Predicted to be involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Predicted to be located in cytosol and membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 192, member A

Involved in negative regulation of proteasomal protein catabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 229, member A

family with sequence similarity 229, member B

family with sequence similarity 21, member A pseudogene

DYZ1 repeat sequence

DYZ1 repeat sequence

DYZ1 repeat sequence

family with sequence similarity 120A opposite strand

Differences in the expression level of this gene are associated with the survival rate of those with glioma. [provided by RefSeq, May 2017]

family with sequence similarity 103, member A2 pseudogene

Predicted to enable RNA binding activity. Predicted to be involved in RNA 5'-cap (guanine-N7)-methylation. Predicted to be located in nucleus. Predicted to be part of mRNA capping enzyme complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 175, member A pseudogene

family with sequence similarity 86, member A pseudogene

family with sequence similarity 149, member B2

family with sequence similarity 60, member C pseudogene

family with sequence similarity 221, member A

family with sequence similarity 221, member B

family with sequence similarity 184, member A

Located in P-body and centriolar satellite. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 184, member B

family with sequence similarity 86, member B2

Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in regulation of translation. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 86, member B1

Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in regulation of translation. Predicted to be part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 213, member A pseudogene

family with sequence similarity 195, member A pseudogene

family with sequence similarity 156, member B

Predicted to enable methylated histone binding activity. Located in nuclear envelope. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 156, member A

Predicted to enable methylated histone binding activity. Located in nuclear envelope. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 215, member B (non-protein coding)

family with sequence similarity 215, member A (non-protein coding)

family with sequence similarity 90, member A1

FAM90A1 belongs to subfamily I of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]).[supplied by OMIM, Oct 2009]

family with sequence similarity 213, member A pseudogene

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 71, member D

Predicted to be involved in flagellated sperm motility. Predicted to act upstream of or within cell morphogenesis and vacuole organization. Predicted to be located in sperm midpiece. Predicted to be active in sperm head. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 71, member B

Predicted to act upstream of or within several processes, including acrosome assembly; single fertilization; and vacuole organization. Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 71, member C

family with sequence similarity 71, member A

This gene encodes a protein that interacts with the Rab2B small GTPase and may be important for integrity of the Golgi body. A knockdown of this gene induces fragmentation of the Golgi, similar to the effect seen with a knockdown of the Rab2B small GTPase. The encoded protein has an N-terminal Rab-binding domain specific for Rab2B. [provided by RefSeq, Feb 2017]

family with sequence similarity 74, member A7

family with sequence similarity 231, member A

family with sequence similarity 231, member B

family with sequence similarity 231, member D

family with sequence similarity 3, member A

This gene encodes a cytokine-like protein. The expression of this gene may be regulated by peroxisome proliferator-activated receptor gamma, and the encoded protein may be involved in the regulation of glucose and lipid metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

family with sequence similarity 3, member C

This gene is a member of the family with sequence similarity 3 (FAM3) family and encodes a secreted protein with a GG domain. A change in expression of this protein has been noted in pancreatic cancer-derived cells. [provided by RefSeq, Mar 2010]

family with sequence similarity 106, member D, pseudogene

family with sequence similarity 65, member C

family with sequence similarity 65, member B

This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. [provided by RefSeq, Sep 2016]

family with sequence similarity 65, member A

Enables 14-3-3 protein binding activity. Involved in several processes, including establishment of Golgi localization; negative regulation of Rho guanyl-nucleotide exchange factor activity; and negative regulation of Rho protein signal transduction. Located in Golgi apparatus; cell leading edge; and membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 175, member A pseudogene

family with sequence similarity 131, member A

family with sequence similarity 131, member B

Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 85, member B

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 207, member A pseudogene

family with sequence similarity 105, member A

Located in cytoplasmic side of endoplasmic reticulum membrane and nuclear envelope. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 129, member A

This gene encodes a member of the family with sequence similarity 129 protein family. This gene is highly expressed in several cancer cells and may serve as a prognostic marker for certain cancers. The encoded protein may play a role in regulating p53-mediated apoptosis. [provided by RefSeq, Sep 2016]

family with sequence similarity 129, member C

family with sequence similarity 129, member B

Enables transcription coactivator activity. Involved in several processes, including gonadotropin secretion; negative regulation of apoptotic process; and regulation of nucleobase-containing compound metabolic process. Located in several cellular components, including adherens junction; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

signal sequence receptor, alpha pseudogene 2

family with sequence similarity 204, member B, pseudogene

MHC class I polypeptide-related sequence B pseudogene

MHC class I polypeptide-related sequence B pseudogene

MHC class I polypeptide-related sequence B pseudogene

MHC class I polypeptide-related sequence B pseudogene

MHC class I polypeptide-related sequence B pseudogene

MHC class I polypeptide-related sequence B pseudogene

family with sequence similarity 173, member B

Enables protein-lysine N-methyltransferase activity. Involved in several processes, including peptidyl-lysine trimethylation; positive regulation of proton-transporting ATP synthase activity, rotational mechanism; and positive regulation of sensory perception of pain. Located in mitochondrial crista. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 173, member A

Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine trimethylation. Located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 103, member A1

Enables RNA binding activity and enzyme activator activity. Involved in 7-methylguanosine mRNA capping. Located in nucleus. Part of mRNA cap methyltransferase RNMT:RAMAC complex and mRNA capping enzyme complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 90, member A27, pseudogene

family with sequence similarity 177, member A1

This gene encodes a member of a conserved protein family. Alternative splicing results in multiple transcript variants. This gene is thought to be associated with susceptibility to juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]

family with sequence similarity 90, member A28, pseudogene

family with sequence similarity 205, member A

Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 46, member D

Antibodies against the protein encoded by this gene were found only in plasma from cancer patients. While it may be a target for immunotherapy, the function of this gene is unknown. [provided by RefSeq, Dec 2009]

family with sequence similarity 46, member A

Enables poly(A) RNA polymerase activity. Predicted to be involved in mRNA stabilization; positive regulation of bone mineralization; and positive regulation of osteoblast differentiation. Predicted to act upstream of or within response to bacterium. Predicted to be located in cytoplasm. Implicated in lung non-small cell carcinoma; osteoarthritis; and osteogenesis imperfecta type 18. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 46, member B

Enables poly(A) RNA polymerase activity. Involved in several processes, including negative regulation of apoptotic process; negative regulation of cell population proliferation; and positive regulation of translation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 46, member C

Enables poly(A) RNA polymerase activity. Involved in mRNA stabilization and negative regulation of cell differentiation. Located in centrosome; cytoplasm; and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 24, member A

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 24, member B

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 197, Y-linked, member 3

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 35, member A pseudogene

family with sequence similarity 86, member A pseudogene

family with sequence similarity 180, member A

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 180, member B

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 86, member A pseudogene

family with sequence similarity 167, member B

family with sequence similarity 167, member A

family with sequence similarity 226, member A (non-protein coding)

family with sequence similarity 226, member B (non-protein coding)

family with sequence similarity 197, Y-linked, member 6

family with sequence similarity 197, Y-linked, member 4, pseudogene

family with sequence similarity 217, member A pseudogene 1

family with sequence similarity 210, member B

Involved in cellular response to estradiol stimulus and positive regulation of erythrocyte differentiation. Located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 90, member A2 pseudogene

family with sequence similarity 90, member A26, pseudogene

family with sequence similarity 187, member B

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 183, member A

Enables microtubule binding activity. Predicted to be involved in flagellated sperm motility. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 8, member A1 pseudogene

MCF.2 cell line derived transforming sequence-like

This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

family with sequence similarity 106, member C, pseudogene

family with sequence similarity 32, member C (pseudogene)

family with sequence similarity 32, member B (pseudogene)

family with sequence similarity 32, member A

Enables RNA binding activity. Predicted to be involved in apoptotic process. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 32, member E (pseudogene)

family with sequence similarity 32, member D (pseudogene)

family with sequence similarity 66, member D

family with sequence similarity 66, member E

family with sequence similarity 66, member B

family with sequence similarity 66, member C

family with sequence similarity 204, member C, pseudogene

family with sequence similarity 47, member C pseudogene

family with sequence similarity 160, member B1

family with sequence similarity 136, member A

This gene encodes a mitochondrially localized protein that is highly conserved across species. The gene is expressed in a variety of tissues including human lymphoblast cells and rat neurosensorial epithelium of the cristaampullaris. A mutation in this gene has been associated with familial Meniere's disease, a chronic disorder of the inner ear. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

family with sequence similarity 166, member A pseudogene

family with sequence similarity 27, member D1

family with sequence similarity 3, member B

Predicted to enable cytokine activity. Involved in insulin secretion. Located in extracellular exosome. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 3, member D

Predicted to enable cytokine activity. Involved in negative regulation of insulin secretion. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 153, member A

family with sequence similarity 153, member B

family with sequence similarity 153, member C, pseudogene

family with sequence similarity 69, member A

This gene encodes a member of the FAM69 family of cysteine-rich type II transmembrane proteins. These proteins localize to the endoplasmic reticulum but their specific functions are unknown. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

family with sequence similarity 198, member A

Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 198, member B

Located in Golgi apparatus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 218, member A

family with sequence similarity 168, member A

Involved in positive regulation of base-excision repair. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 170, member B

Predicted to be involved in fertilization; positive regulation of acrosome reaction; and regulation of fertilization. Located in acrosomal vesicle. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 170, member A

Predicted to enable DNA binding activity and metal ion binding activity. Involved in positive regulation of DNA-templated transcription and transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 91, member A1 pseudogene

family with sequence similarity 206, member A

Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in dendrite morphogenesis; regulation of actin filament polymerization; and regulation of filopodium assembly. Predicted to be located in growth cone. Predicted to be active in several cellular components, including dendrite; filopodium tip; and lamellipodium. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 91, member A1 pseudogene

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 8, member A5 pseudogene

family with sequence similarity 43, member B

family with sequence similarity 43, member A

family with sequence similarity 124B

Located in mitochondrion and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 124A

family with sequence similarity 78, member A

family with sequence similarity 206, member B, pseudogene

family with sequence similarity 21, member C

Enables phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and retromer complex binding activity. Involved in several processes, including endosomal transport; negative regulation of barbed-end actin filament capping; and protein localization to endosome. Located in cytosol; early endosome; and nucleolus. Part of WASH complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 21, member A

Predicted to enable phosphatidylinositol phosphate binding activity and retromer complex binding activity. Involved in protein localization to endosome. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 178, member B

family with sequence similarity 178, member A

Enables ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of cellular component organization; positive regulation of double-strand break repair; and protein localization to site of double-strand break. Located in PML body; chromatin; and site of double-strand break. Implicated in mosaic variegated aneuploidy syndrome. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 160, member B2

family with sequence similarity 60, member A pseudogene

family with sequence similarity 133, member A pseudogene

Cryptidin-related sequence-1C

family with sequence similarity 86, member A pseudogene

family with sequence similarity 231, member C

family with sequence similarity 162, member A

Involved in several processes, including cellular response to hypoxia; positive regulation of cysteine-type endopeptidase activity; and positive regulation of release of cytochrome c from mitochondria. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 162, member B

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 171, member A2

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 171, member A1

Involved in regulation of cell shape and stress fiber assembly. Located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 174, member A

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

MCF.2 cell line derived transforming sequence-like 2

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 136, member A pseudogene

selenocysteine insertion sequence-binding protein 2-like

family with sequence similarity 90, member A16, pseudogene

family with sequence similarity 223, member B (non-protein coding)

family with sequence similarity 57, member B

This gene encodes a transmembrane protein, which may be a likely target of peroxisome proliferator-activated receptor gamma (PPAR-gamma). The product of the orthologous gene in mouse is related to obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

family with sequence similarity 57, member A

The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

MHC class I polypeptide-related sequence B pseudogene

MHC class I polypeptide-related sequence B pseudogene

family with sequence similarity 35, member A pseudogene

family with sequence similarity 186, member B

This gene product is a member of the FAM186 family, however, its exact function is not known. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]

family with sequence similarity 186, member A

testis expressed sequence 13-like pseudogene

Predicted to enable mRNA binding activity. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 92, member A3

family with sequence similarity 92, member A2 (pseudogene)

family with sequence similarity 187, member B pseudogene

family with sequence similarity 160, member A1

Involved in protein localization to perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 71, member E1

Predicted to be involved in defense response to virus; innate immune response; and positive regulation of type I interferon production. Predicted to act upstream of or within cell morphogenesis; single fertilization; and vacuole organization. Predicted to be located in Golgi apparatus. Predicted to be active in sperm head. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 71, member E2

Predicted to act upstream of or within cell morphogenesis; single fertilization; and vacuole organization. Predicted to be active in sperm head. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 86, member A pseudogene

Predicted to enable methyltransferase activity. Predicted to be involved in methylation. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 92, member B

Predicted to be involved in cilium assembly. Predicted to be located in cell projection; centriole; and cytoplasm. Predicted to be active in ciliary basal body and ciliary transition zone. [provided by Alliance of Genome Resources, Mar 2025]

GC-rich sequence DNA-binding factor 2

The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene. [provided by RefSeq, Jul 2008]

family with sequence similarity 217, member A

family with sequence similarity 217, member B

Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

HTLV-1 related endogenous sequence 2

HTLV-1 related endogenous sequence

family with sequence similarity 131, member C pseudogene

family with sequence similarity 131, member C

family with sequence similarity 73, member A

Enables protein heterodimerization activity and protein homodimerization activity. Involved in mitochondrial fusion. Located in mitochondrion and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 73, member B

Enables protein heterodimerization activity and protein homodimerization activity. Involved in mitochondrial fusion. Located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 95, member B1

family with sequence similarity 8, member A1 pseudogene

family with sequence similarity 201, member C

family with sequence similarity 63, member A

Enables K48-linked deubiquitinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and cysteine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Located in nuclear body. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 63, member B

Enables peptidase activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in chromatin remodeling and proteolysis. Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 133, member B

Enables RNA binding activity. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 133, member A

family with sequence similarity 107, member A

Predicted to enable actin binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; negative regulation of focal adhesion assembly; and regulation of cytoskeleton organization. Located in several cellular components, including focal adhesion; ruffle membrane; and stress fiber. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 107, member B

Predicted to act upstream of or within sensory perception of sound. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 127, member C

family with sequence similarity 127, member B

family with sequence similarity 127, member A

Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 228, member B

family with sequence similarity 228, member A

family with sequence similarity 204, member D, pseudogene

family with sequence similarity 175, member A

This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

family with sequence similarity 64, member A pseudogene

family with sequence similarity 90, member A7 pseudogene

family with sequence similarity 85, member A

family with sequence similarity 95, member C

family with sequence similarity 86, member A pseudogene

glioblastoma amplified sequence pseudogene

family with sequence similarity 136, member B, pseudogene

family with sequence similarity 47, member A

family with sequence similarity 220, member A

Predicted to enable STAT family protein binding activity. Predicted to be involved in intracellular signal transduction and negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in acrosomal vesicle. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 195, member B

Involved in regulation of epithelial to mesenchymal transition. Located in cytoplasmic stress granule and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 195, member A

Located in cytoplasmic stress granule and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 192, member B pseudogene

family with sequence similarity 90, member A4 pseudogene

family with sequence similarity 185, member A

Located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 149, member B1

Involved in cilium assembly and protein localization to cilium. Predicted to be located in cilium. Implicated in Joubert syndrome. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 197, Y-linked, member 7, pseudogene

family with sequence similarity 71, member B pseudogene 1

family with sequence similarity 86, member A pseudogene

family with sequence similarity 20, member B pseudogene

family with sequence similarity 138, member C

family with sequence similarity 138, member B

family with sequence similarity 138, member A

family with sequence similarity 138, member F

family with sequence similarity 138, member E

family with sequence similarity 95, member A

family with sequence similarity 13, member B

Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 13, member C

family with sequence similarity 13, member A

Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in cytosol. Implicated in chronic obstructive pulmonary disease. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 90, member A11 pseudogene

human papillomavirus (type 18) E5 central sequence-like 1

family with sequence similarity 241 member A

Located in Golgi apparatus. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 234 member A

Located in cell surface. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 234 member B

Predicted to be located in Golgi apparatus; membrane; and microtubule organizing center. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 241 member B

Predicted to be located in membrane. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 237 member B

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 240 member B

family with sequence similarity 30 member A

family with sequence similarity 200 member C

Located in nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 174 member C

Located in cytoplasm and extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 86 member C1, pseudogene

Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 236 member D

family with sequence similarity 90 member A10

FAM90A10 belongs to subfamily II of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]). For background information on the FAM90A gene family, as well as information on the evolution of FAM90A genes, see FAM90A1 (MIM 613041).[supplied by OMIM, Oct 2009]

family with sequence similarity 235 member A

family with sequence similarity 236 member B

family with sequence similarity 205 member C

Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 166 member C

Predicted to be involved in flagellated sperm motility. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Mar 2025]

G-quadruplex forming sequence containing lncRNA

family with sequence similarity 238 member C

family with sequence similarity 120A2, pseudogene

family with sequence similarity 246 member C (gene/pseudogene)

family with sequence similarity 240 member A

family with sequence similarity 237 member A

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

family with sequence similarity 90 member A17

family with sequence similarity 90 member A23

family with sequence similarity 90 member A16

family with sequence similarity 90 member A9

FAM90A9 belongs to subfamily II of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]). For background information on the FAM90A gene family, as well as information on the evolution of FAM90A genes, see FAM90A1 (MIM 613041).[supplied by OMIM, Oct 2009]

family with sequence similarity 240 member C

family with sequence similarity 236 member C

family with sequence similarity 90 member A7

FAM90A7 belongs to subfamily II of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]). For background information on the FAM90A gene family, as well as information on the evolution of FAM90A genes, see FAM90A1 (MIM 613041).[supplied by OMIM, Oct 2009]

family with sequence similarity 246 member A

family with sequence similarity 90 member A12

family with sequence similarity 90 member A11

family with sequence similarity 90 member A24

family with sequence similarity 90 member A15

family with sequence similarity 90 member A20

family with sequence similarity 90 member A5

family with sequence similarity 90 member A13

family with sequence similarity 90 member A8

family with sequence similarity 246 member B

family with sequence similarity 90 member A18

family with sequence similarity 90 member A14

family with sequence similarity 90 member A3

family with sequence similarity 90 member A19

family with sequence similarity 90 member A22

family with sequence similarity 149 member C

Located in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term read in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term format in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Biocarta Pathways

proteins participating in the role of mal in rho-mediated activation of srf pathway from the Biocarta Pathways dataset.

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the SRF-21415370-HL-1-MOUSE transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

From ChEA Transcription Factor Targets

target genes of the SRF transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

From CORUM Protein Complexes

proteins in the Srf-myogenin-E12 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Ternary complex (GATA4, SRF, MYOCD) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the ELK1-SRF-ELK3 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Foxo4-Srf-Myocd complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the ELK1-SRF-ELK4 complex protein complex from the CORUM Protein Complexes dataset.

From ENCODE Transcription Factor Targets

target genes of the SRF transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term srf in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From JASPAR Predicted Transcription Factor Targets

target genes of the SRF transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

From MotifMap Predicted Transcription Factor Targets

target genes of the SRF transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for SRF from the Pathway Commons Protein-Protein Interactions dataset.

From WikiPathways Pathways 2014

proteins participating in the Serotonin Receptor 2 and ELK-SRF/GATA4 signaling(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From WikiPathways Pathways 2014

proteins participating in the SRF and miRs in Smooth Muscle Differentiation and Proliferation(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset.

From ChEA Transcription Factor Targets 2022

target genes of the SRF-21415370-HL-1-MOUSE transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the SRF gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From WikiPathways Pathways 2024

proteins participating in the SRF and miRs in smooth muscle differentiation and proliferation pathway from the WikiPathways Pathways 2024 dataset.

From WikiPathways Pathways 2024

proteins participating in the Serotonin receptor 2 and ELK SRF GATA4 signaling pathway from the WikiPathways Pathways 2024 dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the SRF transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC5795783-supp_gad.304501.117_Supplemental_Tables_S1-S7.xlsx-Table_S6-Genes_overexpressed_in_myCAF_compared_to_quiescent_PSC_and_iCAF_Ohlund_et_al_2017_that_are_MRTF-SRF-only_targets_SRF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC4677459-NIHMS65392-supplement-Dataset3.xlsx-SRF-Unnamed_2_SRF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC11328887-iovs-65-10-24_s001.xlsx-SRF-independent_Variable_SRF transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the SRF gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From ClinVar Gene-Phenotype Associations

genes associated with the DiGeorge sequence phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

From ClinVar Gene-Phenotype Associations

genes associated with the Septo-optic dysplasia sequence phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

From CORUM Protein Complexes

proteins in the E-box sequence-binding complex protein complex from the CORUM Protein Complexes dataset.

From GAD Gene-Disease Associations

genes associated with the disease longer forms of a repetitive sequence in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sequence in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GO Biological Process Annotations 2015

genes participating in the positive regulation of sequence-specific dna binding transcription factor activity biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of sequence-specific dna binding transcription factor activity biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of rna polymerase ii regulatory region sequence-specific dna binding biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the negative regulation of rna polymerase ii regulatory region sequence-specific dna binding biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the srp-dependent cotranslational protein targeting to membrane, signal sequence recognition biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the regulation of sequence-specific dna binding transcription factor activity biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Biological Process Annotations 2015

genes participating in the dna methylation on cytosine within a cg sequence biological process from the curated GO Biological Process Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the peroxisome membrane class-1 targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the transcription termination site sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the sequence-specific dna binding transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the chromatin insulator sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the ligand-activated sequence-specific dna binding rna polymerase ii transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii sequence-specific dna binding transcription factor binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase i core element sequence-specific dna binding transcription factor recruiting transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase i core element sequence-specific dna binding transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the er retention sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the transcription regulatory region sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii core promoter sequence-specific dna binding transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii regulatory region sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii core promoter proximal region sequence-specific dna binding transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii transcription regulatory region sequence-specific dna binding transcription factor activity involved in negative regulation of transcription molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the intronic transcription regulatory region sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii transcription regulatory region sequence-specific dna binding transcription factor activity involved in positive regulation of transcription molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase i regulatory region sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the kdel sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii core promoter proximal region sequence-specific dna binding transcription factor activity involved in positive regulation of transcription molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii core promoter sequence-specific dna binding transcription factor activity involved in preinitiation complex assembly molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the signal sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the core promoter sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the peroxisome targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the sequence-specific transcription regulatory region dna binding rna polymerase ii transcription factor recruiting transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the sequence-specific dna binding transcription factor recruiting transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase i core element sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii core promoter sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the sequence-specific dna binding rna polymerase ii transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii distal enhancer sequence-specific dna binding transcription factor activity involved in positive regulation of transcription molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the sequence-specific dna binding rna polymerase recruiting transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii distal enhancer sequence-specific dna binding transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii core promoter proximal region sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the peroxisome membrane targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the nuclear localization sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii distal enhancer sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii core promoter proximal region sequence-specific dna binding transcription factor activity involved in negative regulation of transcription molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii intronic transcription regulatory region sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the core promoter proximal region sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the direct ligand regulated sequence-specific dna binding transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the enhancer sequence-specific dna binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the rna polymerase ii distal enhancer sequence-specific dna binding transcription factor activity involved in negative regulation of transcription molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the sequence-specific dna binding rna polymerase i transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the selenocysteine insertion sequence binding molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From GO Molecular Function Annotations 2015

genes performing the estrogen-activated sequence-specific dna binding rna polymerase ii transcription factor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

From HPO Gene-Disease Associations

genes associated with the fetal akinesia sequence phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

From HPO Gene-Disease Associations

genes associated with the pierre-robin sequence phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein of unknown function with TPD sequence-motif protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Testis-expressed sequence 37 protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pre-rRNA-processing protein IPI1/Testis-expressed sequence 10 protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GC-rich sequence DNA-binding factor domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Testis-expressed sequence 15 protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Neuroblastoma-amplified sequence, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Breast carcinoma amplified sequence 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Testis-expressed sequence 12 protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Testis-expressed sequence 13 protein family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the GC-rich sequence DNA-binding factor protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Testis-expressed sequence 35 protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Triple repetitive-sequence of QXXK/R protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Sequence-specific single-strand DNA-binding protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Testis-expressed sequence 33 protein family protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From MPO Gene-Phenotype Associations

gene mutations causing the reversion by viral sequence excision phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the fetal akinesia deformation sequence phenotype from the curated OMIM Gene-Disease Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the robin sequence with cleft mandible and limb anomalies phenotype from the curated OMIM Gene-Disease Associations dataset.

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term sequence-deletion in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

From Reactome Pathways 2014

proteins participating in the A tetrasaccharide linker sequence is required for GAG synthesis pathway from the Reactome Pathways dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Oligohydramnios Sequence in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Rieger Eye Malformation Sequence in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Urethral Obstruction Sequence in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Pierre Robin Sequence With Pectus Excavatum And Rib And Scapular Anomalies in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Early Severe Fetal Akinesia Sequence in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

From DisGeNET Gene-Phenotype Associations

genes associated with the phenotype Holoprosencephaly With Fetal Akinesia-Hypokinesia Sequence in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset.

From GO Biological Process Annotations 2023

genes participating in the negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the protein insertion into ER membrane by stop-transfer membrane-anchor sequence biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the regulation of RNA polymerase II regulatory region sequence-specific DNA binding biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Biological Process Annotations 2023

genes participating in the DNA methylation on cytosine within a CG sequence biological process from the curated GO Biological Process Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the cis-regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the sequence-specific double-stranded DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the core promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase II transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the KDEL sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the mitochondrion targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the sequence-specific mRNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase II core promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase I core promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase I cis-regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the nuclear localization sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the non-sequence-specific DNA binding, bending molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase III transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the mitochondrial promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the peroxisome membrane class-1 targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase III type 1 promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase III type 2 promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase III type 3 promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the intronic transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the chromatin insulator sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the peroxisome targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the peroxisome membrane targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the signal sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the transcription termination site sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the ER retention sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the selenocysteine insertion sequence binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase I transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the sequence-specific single stranded DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From GO Molecular Function Annotations 2023

genes performing the RNA polymerase III cis-regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2023 dataset.

From MGI Mouse Phenotype Associations 2023

gene mutations causing the reversion by viral sequence excision phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.

From Reactome Pathways 2024

proteins participating in the A tetrasaccharide linker sequence is required for GAG synthesis pathway from the Reactome Pathways 2024 dataset.

From GO Biological Process Annotations 2025

genes participating in the negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the protein insertion into ER membrane by stop-transfer membrane-anchor sequence biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Biological Process Annotations 2025

genes participating in the regulation of RNA polymerase II regulatory region sequence-specific DNA binding biological process from the curated GO Biological Process Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase II cis-regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the cis-regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the sequence-specific double-stranded DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the core promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase II transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the nuclear localization sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the KDEL sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the mitochondrion targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the sequence-specific mRNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase II core promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase I core promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase I cis-regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the non-sequence-specific DNA binding, bending molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the protein-RNA sequence-specific adaptor activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase III transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the mitochondrial promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the peroxisome membrane class-1 targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase III type 1 promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase III type 2 promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase III type 3 promoter sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the intronic transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the chromatin insulator sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase I transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the peroxisome targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the peroxisome membrane targeting sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the transcription termination site sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the ER retention sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the selenocysteine insertion sequence binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the sequence-specific single stranded DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From GO Molecular Function Annotations 2025

genes performing the RNA polymerase III cis-regulatory region sequence-specific DNA binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occuring with the disease Fetal akinesia deformation sequence syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

From DISEASES Text-mining Gene-Disease Association Evidence Scores 2025

genes co-occuring with the disease Fetal akinesia deformation sequence syndrome 4 in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Fetal akinesia deformation sequence phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Septo-optic dysplasia sequence phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Caudal regression sequence phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Holoprosencephaly sequence phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the MHC class I polypeptide-related sequence A levels phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the ANTIHEMOPHILIC FACTOR, PEGYLATED (MW 20000) HUMAN SEQUENCE RECOMBINANT drug from theDGIdb Drug Targets 2026 dataset.