| Name |
|---|
Sorafenib-resistant KIT mutants Gene Setproteins participating in the Sorafenib-resistant KIT mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of KIT mutants Gene Setproteins participating in the Drug resistance of KIT mutants pathway from the Reactome Pathways 2024 dataset. |
KIT mutants bind TKIs Gene Setproteins participating in the KIT mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
Signaling by extracellular domain mutants of KIT Gene Setproteins participating in the Signaling by extracellular domain mutants of KIT pathway from the Reactome Pathways 2024 dataset. |
Signaling by juxtamembrane domain KIT mutants Gene Setproteins participating in the Signaling by juxtamembrane domain KIT mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by kinase domain mutants of KIT Gene Setproteins participating in the Signaling by kinase domain mutants of KIT pathway from the Reactome Pathways 2024 dataset. |
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants Gene Setproteins participating in the Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants pathway from the Reactome Pathways 2024 dataset. |
sorafenib Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical sorafenib from the curated CTD Gene-Chemical Interactions dataset. |
Sorafenib Gene Setinteracting proteins for the Sorafenib drug from the curated DrugBank Drug Targets dataset. |
sorafenib Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term sorafenib in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
sorafenib Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the sorafenib ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
Sorafenib Gene SetFrom HMDB Metabolites of Enzymes interacting proteins for the Sorafenib metabolite from the curated HMDB Metabolites of Enzymes dataset. |
Sorafenib Gene SetFrom LINCS KinomeScan Kinase Inhibitor Targets kinases inhibited by the Sorafenib small molecule from the KinomeScan Kinase Inhibitor Targets dataset. |
Sorafenib response - Toxicity Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the Sorafenib response - Toxicity phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
SORAFENIB Gene Setinteracting proteins for the SORAFENIB drug from theDGIdb Drug Targets 2026 dataset. |
SORAFENIB TOSYLATE Gene Setinteracting proteins for the SORAFENIB TOSYLATE drug from theDGIdb Drug Targets 2026 dataset. |
kit Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term kit in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
kit signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the kit signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
regulation of kit signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the regulation of kit signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
negative regulation of kit signaling pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the negative regulation of kit signaling pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
c-Kit-binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the c-Kit-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
KIT Gene SetFrom KEA Substrates of Kinases substrates of the kinase KIT from the curated KEA Substrates of Kinases dataset. |
KIT Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for KIT from the Pathway Commons Protein-Protein Interactions dataset. |
KIT Gene SetFrom PhosphoSitePlus Substrates of Kinases substrates of the kinase KIT from the curated PhosphoSitePlus Substrates of Kinases dataset. |
Signaling events mediated by Stem cell factor receptor (c-Kit) Gene SetFrom PID Pathways proteins participating in the Signaling events mediated by Stem cell factor receptor (c-Kit) pathway from the PID Pathways dataset. |
Signaling by SCF-KIT Gene Setproteins participating in the Signaling by SCF-KIT pathway from the Reactome Pathways dataset. |
Regulation of KIT signaling Gene Setproteins participating in the Regulation of KIT signaling pathway from the Reactome Pathways dataset. |
Kit Receptor Signaling Pathway(Mus musculus) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Kit Receptor Signaling Pathway(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset. |
Kit receptor signaling pathway(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Kit receptor signaling pathway(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
Kit signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the Kit signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
negative regulation of Kit signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the negative regulation of Kit signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
regulation of Kit signaling pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the regulation of Kit signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
KIT Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the KIT gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
Mouse - Motor Cortex - Cluster - Kit+ Layer 6 glutamatergic neuron, corticothalamic-projecting_1 Gene SetFrom HuBMAP Azimuth Cell Type Annotations genes associated with the Mouse - Motor Cortex - Cluster - Kit+ Layer 6 glutamatergic neuron, corticothalamic-projecting_1 cell type from the HuBMAP Azimuth Cell Type Annotations dataset. |
Mouse - Motor Cortex - Cluster - Kit+ Layer 6 glutamatergic neuron, corticothalamic-projecting_2 Gene SetFrom HuBMAP Azimuth Cell Type Annotations genes associated with the Mouse - Motor Cortex - Cluster - Kit+ Layer 6 glutamatergic neuron, corticothalamic-projecting_2 cell type from the HuBMAP Azimuth Cell Type Annotations dataset. |
KIT Gene SetFrom Kinase Library Tyrosine Kinome Atlas substrates of the kinase KIT from the Kinase Library Tyrosine Kinome Atlas dataset. |
Kit receptor signaling Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Kit receptor signaling pathway from the WikiPathways Pathways 2024 dataset. |
Regulation of KIT signaling Gene Setproteins participating in the Regulation of KIT signaling pathway from the Reactome Pathways 2024 dataset. |
Signaling by KIT in disease Gene Setproteins participating in the Signaling by KIT in disease pathway from the Reactome Pathways 2024 dataset. |
Signaling by SCF-KIT Gene Setproteins participating in the Signaling by SCF-KIT pathway from the Reactome Pathways 2024 dataset. |
Kit signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the Kit signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative regulation of Kit signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the negative regulation of Kit signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
regulation of Kit signaling pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the regulation of Kit signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
c-Kit-IN-1_SW 1271 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_J82 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_A-172 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_BT-474 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SNU-1 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_HOP62 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SW 900 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_Panc 03.27 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H460 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_RKO Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_LOX-IMVI Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_Hs 766T Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_A549 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H1792 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_A498 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_HEC-1-A Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_HT-29 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H2030 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SW48 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H661 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_PANC-1 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_CHP-212 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H2122 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_CFPAC-1 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H596 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_LS 180 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_MIA PaCa-2 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_HS-578T Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SK-MEL-2 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H1573 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H2347 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_hTERT-HPNE Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SNU-423 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_NCI-H23 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SHP-77 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_C-33 A Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_A-427 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_AN3 CA Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_HepG2/C3A Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SW 1088 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_RPMI-7951 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_KATO III Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_LoVo Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_C32 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_HCT15 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_COLO 205 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_AsPC-1 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SW480 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_H4 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
c-Kit-IN-1_SW1417 Gene SetFrom Tahoe Therapeutics Tahoe 100M Perturbation Atlas genes differentially expressed following the c-Kit-IN-1_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset. |
Mastocytosis (KIT D816V positive) Gene SetFrom GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the Mastocytosis (KIT D816V positive) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset. |
CHMFL-KIT-64 Gene Setinteracting proteins for the CHMFL-KIT-64 drug from theDGIdb Drug Targets 2026 dataset. |
CHMFL-KIT-8140 Gene Setinteracting proteins for the CHMFL-KIT-8140 drug from theDGIdb Drug Targets 2026 dataset. |
KIT-MUTANT INHIBITOR DCC-3009 Gene Setinteracting proteins for the KIT-MUTANT INHIBITOR DCC-3009 drug from theDGIdb Drug Targets 2026 dataset. |
PMC4083110-supp_M113.034876_mcp.M113.034876-9.xlsx-AR-KIT-MET-GAB1_HPRD-SH2_domain_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC4083110-supp_M113.034876_mcp.M113.034876-9.xlsx-AR-KIT-MET-GAB1_HPRD-SH2_domain_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC4083110-supp_M113.034876_mcp.M113.034876-9.xlsx-AR-KIT-MET-GAB1_BioGRID-SH2_domain_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC4083110-supp_M113.034876_mcp.M113.034876-9.xlsx-AR-KIT-MET-GAB1_BioGRID-SH2_domain_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC4083110-supp_M113.034876_mcp.M113.034876-9.xlsx-AR-KIT-MET-GAB1_IntACT-SH2_domain_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC4083110-supp_M113.034876_mcp.M113.034876-9.xlsx-AR-KIT-MET-GAB1_IntACT-SH2_domain_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
KIT Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the KIT gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
mutants Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term mutants in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Setproteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways dataset. |
SMAD2/3 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways dataset. |
TGFBR1 KD Mutants in Cancer Gene Setproteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
AXIN missense mutants destabilize the destruction complex Gene Setproteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR3 mutants Gene Setproteins participating in the Signaling by FGFR3 mutants pathway from the Reactome Pathways dataset. |
APC truncation mutants have impaired AXIN binding Gene Setproteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways dataset. |
APC truncation mutants are not K63 polyubiquitinated Gene Setproteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways dataset. |
S37 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S37 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
Signaling by FGFR2 amplification mutants Gene Setproteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways dataset. |
S33 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S33 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
FBXW7 Mutants and NOTCH1 in Cancer Gene Setproteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 mutants Gene Setproteins participating in the Signaling by FGFR1 mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 fusion mutants Gene Setproteins participating in the Signaling by FGFR1 fusion mutants pathway from the Reactome Pathways dataset. |
TCF7L2 mutants don't bind CTBP Gene Setproteins participating in the TCF7L2 mutants don't bind CTBP pathway from the Reactome Pathways dataset. |
Signaling by FGFR2 mutants Gene Setproteins participating in the Signaling by FGFR2 mutants pathway from the Reactome Pathways dataset. |
RNF mutants show enhanced WNT signaling and proliferation Gene Setproteins participating in the RNF mutants show enhanced WNT signaling and proliferation pathway from the Reactome Pathways dataset. |
Signaling by FGFR4 mutants Gene Setproteins participating in the Signaling by FGFR4 mutants pathway from the Reactome Pathways dataset. |
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
truncated APC mutants destabilize the destruction complex Gene Setproteins participating in the truncated APC mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
AXIN mutants destabilize the destruction complex, activating WNT signaling Gene Setproteins participating in the AXIN mutants destabilize the destruction complex, activating WNT signaling pathway from the Reactome Pathways dataset. |
Activated point mutants of FGFR2 Gene Setproteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways dataset. |
TGFBR2 Kinase Domain Mutants in Cancer Gene Setproteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by FGFR mutants Gene Setproteins participating in the Signaling by FGFR mutants pathway from the Reactome Pathways dataset. |
Signaling by FGFR1 amplification mutants Gene Setproteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways dataset. |
Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways dataset. |
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex Gene Setproteins participating in the phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex pathway from the Reactome Pathways dataset. |
TGFBR1 LBD Mutants in Cancer Gene Setproteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways dataset. |
S45 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the S45 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
T41 mutants of beta-catenin aren't phosphorylated Gene Setproteins participating in the T41 mutants of beta-catenin aren't phosphorylated pathway from the Reactome Pathways dataset. |
AMER1 mutants destabilize the destruction complex Gene Setproteins participating in the AMER1 mutants destabilize the destruction complex pathway from the Reactome Pathways dataset. |
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling Gene Setproteins participating in the misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway from the Reactome Pathways dataset. |
SMAD4 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways dataset. |
TGFBR2 MSI Frameshift Mutants in Cancer Gene Setproteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways dataset. |
Signaling by activated point mutants of FGFR1 Gene Setproteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways dataset. |
Signaling by activated point mutants of FGFR3 Gene Setproteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways dataset. |
misspliced GSK3beta mutants stabilize beta-catenin Gene Setproteins participating in the misspliced GSK3beta mutants stabilize beta-catenin pathway from the Reactome Pathways dataset. |
ALK mutants bind TKIs Gene Setproteins participating in the ALK mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
APC truncation mutants are not K63 polyubiquitinated Gene Setproteins participating in the APC truncation mutants are not K63 polyubiquitinated pathway from the Reactome Pathways 2024 dataset. |
APC truncation mutants have impaired AXIN binding Gene Setproteins participating in the APC truncation mutants have impaired AXIN binding pathway from the Reactome Pathways 2024 dataset. |
AXIN missense mutants destabilize the destruction complex Gene Setproteins participating in the AXIN missense mutants destabilize the destruction complex pathway from the Reactome Pathways 2024 dataset. |
Activated point mutants of FGFR2 Gene Setproteins participating in the Activated point mutants of FGFR2 pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S33 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S33 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S37 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S37 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 S45 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 S45 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
CTNNB1 T41 mutants aren't phosphorylated Gene Setproteins participating in the CTNNB1 T41 mutants aren't phosphorylated pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 HD Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Constitutive Signaling by NOTCH1 PEST Domain Mutants Gene Setproteins participating in the Constitutive Signaling by NOTCH1 PEST Domain Mutants pathway from the Reactome Pathways 2024 dataset. |
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Gene Setproteins participating in the Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) pathway from the Reactome Pathways 2024 dataset. |
Defective translocation of RB1 mutants to the nucleus Gene Setproteins participating in the Defective translocation of RB1 mutants to the nucleus pathway from the Reactome Pathways 2024 dataset. |
Drug resistance in ERBB2 KD mutants Gene Setproteins participating in the Drug resistance in ERBB2 KD mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance in ERBB2 TMD/JMD mutants Gene Setproteins participating in the Drug resistance in ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of ALK mutants Gene Setproteins participating in the Drug resistance of ALK mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of FLT3 mutants Gene Setproteins participating in the Drug resistance of FLT3 mutants pathway from the Reactome Pathways 2024 dataset. |
Drug resistance of PDGFR mutants Gene Setproteins participating in the Drug resistance of PDGFR mutants pathway from the Reactome Pathways 2024 dataset. |
FBXW7 Mutants and NOTCH1 in Cancer Gene Setproteins participating in the FBXW7 Mutants and NOTCH1 in Cancer pathway from the Reactome Pathways 2024 dataset. |
FLT3 mutants bind TKIs Gene Setproteins participating in the FLT3 mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
FLT3 signaling by CBL mutants Gene Setproteins participating in the FLT3 signaling by CBL mutants pathway from the Reactome Pathways 2024 dataset. |
Hh mutants abrogate ligand secretion Gene Setproteins participating in the Hh mutants abrogate ligand secretion pathway from the Reactome Pathways 2024 dataset. |
Hh mutants are degraded by ERAD Gene Setproteins participating in the Hh mutants are degraded by ERAD pathway from the Reactome Pathways 2024 dataset. |
PDGFR mutants bind TKIs Gene Setproteins participating in the PDGFR mutants bind TKIs pathway from the Reactome Pathways 2024 dataset. |
RAS GTPase cycle mutants Gene Setproteins participating in the RAS GTPase cycle mutants pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to AEE788 Gene Setproteins participating in the Resistance of ERBB2 KD mutants to AEE788 pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to afatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to afatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to lapatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to lapatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to neratinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to neratinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to osimertinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to osimertinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to sapitinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to sapitinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to tesevatinib Gene Setproteins participating in the Resistance of ERBB2 KD mutants to tesevatinib pathway from the Reactome Pathways 2024 dataset. |
Resistance of ERBB2 KD mutants to trastuzumab Gene Setproteins participating in the Resistance of ERBB2 KD mutants to trastuzumab pathway from the Reactome Pathways 2024 dataset. |
SMAD2/3 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD2/3 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
SMAD2/3 Phosphorylation Motif Mutants in Cancer Gene Setproteins participating in the SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
SMAD4 MH2 Domain Mutants in Cancer Gene Setproteins participating in the SMAD4 MH2 Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
STAT5 activation downstream of FLT3 ITD mutants Gene Setproteins participating in the STAT5 activation downstream of FLT3 ITD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ALK fusions and activated point mutants Gene Setproteins participating in the Signaling by ALK fusions and activated point mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by AMER1 mutants Gene Setproteins participating in the Signaling by AMER1 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by APC mutants Gene Setproteins participating in the Signaling by APC mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by AXIN mutants Gene Setproteins participating in the Signaling by AXIN mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by CTNNB1 phospho-site mutants Gene Setproteins participating in the Signaling by CTNNB1 phospho-site mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 ECD mutants Gene Setproteins participating in the Signaling by ERBB2 ECD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 KD Mutants Gene Setproteins participating in the Signaling by ERBB2 KD Mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by ERBB2 TMD/JMD mutants Gene Setproteins participating in the Signaling by ERBB2 TMD/JMD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FGFR1 amplification mutants Gene Setproteins participating in the Signaling by FGFR1 amplification mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FGFR2 amplification mutants Gene Setproteins participating in the Signaling by FGFR2 amplification mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by FLT3 ITD and TKD mutants Gene Setproteins participating in the Signaling by FLT3 ITD and TKD mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by GSK3beta mutants Gene Setproteins participating in the Signaling by GSK3beta mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by LRP5 mutants Gene Setproteins participating in the Signaling by LRP5 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MAP2K mutants Gene Setproteins participating in the Signaling by MAP2K mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MAPK mutants Gene Setproteins participating in the Signaling by MAPK mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by MRAS-complex mutants Gene Setproteins participating in the Signaling by MRAS-complex mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 HD Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by NOTCH1 PEST Domain Mutants in Cancer Gene Setproteins participating in the Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
Signaling by PDGFRA extracellular domain mutants Gene Setproteins participating in the Signaling by PDGFRA extracellular domain mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants Gene Setproteins participating in the Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAF1 mutants Gene Setproteins participating in the Signaling by RAF1 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS GAP mutants Gene Setproteins participating in the Signaling by RAS GAP mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS GTPase mutants Gene Setproteins participating in the Signaling by RAS GTPase mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RAS mutants Gene Setproteins participating in the Signaling by RAS mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by RNF43 mutants Gene Setproteins participating in the Signaling by RNF43 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by TCF7L2 mutants Gene Setproteins participating in the Signaling by TCF7L2 mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by activated point mutants of FGFR1 Gene Setproteins participating in the Signaling by activated point mutants of FGFR1 pathway from the Reactome Pathways 2024 dataset. |
Signaling by activated point mutants of FGFR3 Gene Setproteins participating in the Signaling by activated point mutants of FGFR3 pathway from the Reactome Pathways 2024 dataset. |
Signaling by cytosolic FGFR1 fusion mutants Gene Setproteins participating in the Signaling by cytosolic FGFR1 fusion mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by high-kinase activity BRAF mutants Gene Setproteins participating in the Signaling by high-kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling by moderate kinase activity BRAF mutants Gene Setproteins participating in the Signaling by moderate kinase activity BRAF mutants pathway from the Reactome Pathways 2024 dataset. |
Signaling downstream of RAS mutants Gene Setproteins participating in the Signaling downstream of RAS mutants pathway from the Reactome Pathways 2024 dataset. |
TGFBR1 KD Mutants in Cancer Gene Setproteins participating in the TGFBR1 KD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR1 LBD Mutants in Cancer Gene Setproteins participating in the TGFBR1 LBD Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR2 Kinase Domain Mutants in Cancer Gene Setproteins participating in the TGFBR2 Kinase Domain Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |
TGFBR2 MSI Frameshift Mutants in Cancer Gene Setproteins participating in the TGFBR2 MSI Frameshift Mutants in Cancer pathway from the Reactome Pathways 2024 dataset. |