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Achilles Cell Line Gene Essentiality Pr
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BioGPS Cell Line Gene Expression Pr
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BioGPS Human Cell Type and Tissue Gene Expression Pr
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BioGPS Mouse Cell Type and Tissue Gene Expression Pr
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CCLE Cell Line Gene CNV Pr
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CCLE Cell Line Gene Expression Pr
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CCLE Cell Line Gene Mutation Pr
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COSMIC Cell Line Gene CNV Pr
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COSMIC Cell Line Gene Mutation Pr
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GDSC Cell Line Gene Expression Pr
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Heiser et al., PNAS, 2011 Cell Line Gene Expression Pr
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HPA Cell Line Gene Expression Pr
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HPM Cell Type and Tissue Protein Expression Pr
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Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Pr
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Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Pr
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Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Pr
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ProteomicsDB Cell Type and Tissue Protein Expression Pr
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Roadmap Epigenomics Cell and Tissue DNA Methylation Pr
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Roadmap Epigenomics Cell and Tissue Gene Expression Pr
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Sanger Dependency Map Cancer Cell Line Proteomics DatasetFrom Sanger Cancer Dependency Map Protein intensity values acquired using data-independent acquisition mass spectrometry (DIA-MS). |
Tabula Sapiens Gene-Cell Associations DatasetFrom Tabula Sapiens Gene expression data from Tabula Sapiens scRNA-seq counts |
CCLE Cell Line Proteomics DatasetFrom Cancer Cell Line Encyclopedia Protein intensity values acquired using mass spectrometry across human cancerous cell lines |
HuBMAP Azimuth Cell Type Annotations DatasetFrom The Human BioMolecular Atlas Program
Gene-cell type annotations from integrated reference scRNA-seq gene expression pr |
CellMarker Gene-Cell Type Associations DatasetFrom CellMarker Cell type markers across various tissues from human and mouse scRNA-seq |
Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures DatasetFrom Replogle et al., Cell, 2022
Gene expression pr |
Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures DatasetFrom Replogle et al., Cell, 2022
Gene expression pr |
Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures DatasetFrom Replogle et al., Cell, 2022
Gene expression pr |
CM4AI U2OS Cell Map Protein Localization Assemblies DatasetFrom Cell Maps for AI Protein localization assemblies constructed from integrating AP-MS biomolecular interaction and IF imaging data |
CM4AI KOLF21J CRISPRi Gene Perturbation Atlas DatasetFrom Cell Maps for AI
Gene expression pr |
GREB1L Gene
growth
Acts upstream |
RPRD1A Gene
This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator |
RPRD1B Gene
Enables RNA polymerase II complex binding activity and identical protein binding activity. Involved in several processes, including RNA polymerase II promoter clearance; positive |
RPRD2 Gene
Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in mRNA 3'-end processing. Part |
GREB1 Gene
growth
This gene is an estrogen-responsive gene that is an early response gene in the estrogen receptor-regulated pathway. It is thought to play an important role in hormone-responsive tissues and cancer. Three alternatively spliced transcript variants encoding distinct is |
LOC100130602 Gene
|
PELATON Gene
plaque enriched lncRNA in atherosclerotic and inflammatory bowel macrophage |
PRAL Gene
p53 |
SRD5A2 Genesteroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008] |
SRD5A1 Genesteroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion |
SRD5A1P1 Genesteroid-5-alpha-reductase, alpha polypeptide 1 pseudogene 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha pseudogene) |
TRAV23DV6 GeneT cell receptor alpha variable 23/delta variable 6
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ32 GeneT cell receptor alpha joining 32
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
DEFA6 Genedefensin, alpha 6, Paneth cell-specific
Defensins are a family |
DEFA5 Genedefensin, alpha 5, Paneth cell-specific
Defensins are a family |
TRAJ29 GeneT cell receptor alpha joining 29
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ28 GeneT cell receptor alpha joining 28
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ27 GeneT cell receptor alpha joining 27
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ26 GeneT cell receptor alpha joining 26
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ25 GeneT cell receptor alpha joining 25 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ24 GeneT cell receptor alpha joining 24
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ23 GeneT cell receptor alpha joining 23
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ22 GeneT cell receptor alpha joining 22
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ21 GeneT cell receptor alpha joining 21
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ20 GeneT cell receptor alpha joining 20
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV5 GeneT cell receptor alpha variable 5
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV29DV5 GeneT cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV14DV4 GeneT cell receptor alpha variable 14/delta variable 4
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ16 GeneT cell receptor alpha joining 16
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ17 GeneT cell receptor alpha joining 17
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ14 GeneT cell receptor alpha joining 14
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ15 GeneT cell receptor alpha joining 15
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ12 GeneT cell receptor alpha joining 12
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ13 GeneT cell receptor alpha joining 13
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ10 GeneT cell receptor alpha joining 10
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ11 GeneT cell receptor alpha joining 11
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ18 GeneT cell receptor alpha joining 18
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ19 GeneT cell receptor alpha joining 19 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV20 GeneT cell receptor alpha variable 20
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
PTCRA Genepre T-cell antigen receptor alpha
The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different is |
TRAV36DV7 GeneT cell receptor alpha variable 36/delta variable 7
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ49 GeneT cell receptor alpha joining 49
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ48 GeneT cell receptor alpha joining 48
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ41 GeneT cell receptor alpha joining 41
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ40 GeneT cell receptor alpha joining 40
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ43 GeneT cell receptor alpha joining 43
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ42 GeneT cell receptor alpha joining 42
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ45 GeneT cell receptor alpha joining 45
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ44 GeneT cell receptor alpha joining 44
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ47 GeneT cell receptor alpha joining 47
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ46 GeneT cell receptor alpha joining 46
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV38-2DV8 GeneT cell receptor alpha variable 38-2/delta variable 8
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV31 GeneT cell receptor alpha variable 31 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ30 GeneT cell receptor alpha joining 30
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ31 GeneT cell receptor alpha joining 31
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ33 GeneT cell receptor alpha joining 33
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ34 GeneT cell receptor alpha joining 34
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ35 GeneT cell receptor alpha joining 35 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ36 GeneT cell receptor alpha joining 36
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ37 GeneT cell receptor alpha joining 37
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ38 GeneT cell receptor alpha joining 38
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ39 GeneT cell receptor alpha joining 39
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV2 GeneT cell receptor alpha variable 2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV3 GeneT cell receptor alpha variable 3 (gene/pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV4 GeneT cell receptor alpha variable 4
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV6 GeneT cell receptor alpha variable 6
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV7 GeneT cell receptor alpha variable 7
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
PARD6A Genepar-6 family cell polarity regulator alpha
This gene is a member |
TRAV22 GeneT cell receptor alpha variable 22
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV21 GeneT cell receptor alpha variable 21
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV27 GeneT cell receptor alpha variable 27
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV25 GeneT cell receptor alpha variable 25
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV24 GeneT cell receptor alpha variable 24
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV28 GeneT cell receptor alpha variable 28 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ58 GeneT cell receptor alpha joining 58 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ56 GeneT cell receptor alpha joining 56
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ57 GeneT cell receptor alpha joining 57
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ54 GeneT cell receptor alpha joining 54
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV26-1 GeneT cell receptor alpha variable 26-1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV26-2 GeneT cell receptor alpha variable 26-2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV9-1 GeneT cell receptor alpha variable 9-1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV9-2 GeneT cell receptor alpha variable 9-2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ61 GeneT cell receptor alpha joining 61 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ60 GeneT cell receptor alpha joining 60 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV18 GeneT cell receptor alpha variable 18
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV19 GeneT cell receptor alpha variable 19
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV10 GeneT cell receptor alpha variable 10
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV11 GeneT cell receptor alpha variable 11 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV16 GeneT cell receptor alpha variable 16
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV17 GeneT cell receptor alpha variable 17
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV15 GeneT cell receptor alpha variable 15 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV8-1 GeneT cell receptor alpha variable 8-1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV8-3 GeneT cell receptor alpha variable 8-3
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV8-2 GeneT cell receptor alpha variable 8-2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV8-5 GeneT cell receptor alpha variable 8-5 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV8-4 GeneT cell receptor alpha variable 8-4
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV8-7 GeneT cell receptor alpha variable 8-7 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV8-6 GeneT cell receptor alpha variable 8-6
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAC GeneT cell receptor alpha constant
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRA GeneT cell receptor alpha locus
Enables signaling receptor activity. Contributes to peptide antigen binding activity. Involved in T cell activation involved in immune response; T cell mediated cytotoxicity directed against tumor cell target; and detection |
TRAJ59 GeneT cell receptor alpha joining 59 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ52 GeneT cell receptor alpha joining 52
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ53 GeneT cell receptor alpha joining 53
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ50 GeneT cell receptor alpha joining 50
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ51 GeneT cell receptor alpha joining 51 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ55 GeneT cell receptor alpha joining 55 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV41 GeneT cell receptor alpha variable 41
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV40 GeneT cell receptor alpha variable 40
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV1-1 GeneT cell receptor alpha variable 1-1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV1-2 GeneT cell receptor alpha variable 1-2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV38-1 GeneT cell receptor alpha variable 38-1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV34 GeneT cell receptor alpha variable 34
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV35 GeneT cell receptor alpha variable 35
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV37 GeneT cell receptor alpha variable 37 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV30 GeneT cell receptor alpha variable 30
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV32 GeneT cell receptor alpha variable 32 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV33 GeneT cell receptor alpha variable 33 (pseudogene)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV39 GeneT cell receptor alpha variable 39
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV12-1 GeneT cell receptor alpha variable 12-1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV12-3 GeneT cell receptor alpha variable 12-3
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV12-2 GeneT cell receptor alpha variable 12-2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV13-1 GeneT cell receptor alpha variable 13-1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAV13-2 GeneT cell receptor alpha variable 13-2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ4 GeneT cell receptor alpha joining 4
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ5 GeneT cell receptor alpha joining 5
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ6 GeneT cell receptor alpha joining 6
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ7 GeneT cell receptor alpha joining 7
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ1 GeneT cell receptor alpha joining 1 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ2 GeneT cell receptor alpha joining 2 (non-functional)
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ3 GeneT cell receptor alpha joining 3
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ8 GeneT cell receptor alpha joining 8
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRAJ9 GeneT cell receptor alpha joining 9
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
ITGA2 Gene
integrin, alpha 2 (CD49B, alpha 2 subunit
This gene encodes the alpha subunit |
ITGA3 Gene
integrin, alpha 3 (antigen CD49C, alpha 3 subunit
The gene encodes a member |
ITGA4 Gene
integrin, alpha 4 (antigen CD49D, alpha 4 subunit
The gene encodes a member |
ITGA5 Geneintegrin, alpha 5 (fibronectin receptor, alpha polypeptide)
The product |
ITGAL Geneintegrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed |
ITGAE Geneintegrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
Integrins are heterodimeric integral membrane proteins composed |
LOC100421093 Genekaryopherin alpha 3 (importin alpha 4) pseudogene |
LOC401913 GeneABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) pseudogene |
LOC100422717 Gene
pterin-4 alpha-carbinolamine dehydratase/dimerization c |
TFAP2A Genetranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription |
KPNA7 Genekaryopherin alpha 7 (importin alpha 8)
The transport |
KPNA6 Genekaryopherin alpha 6 (importin alpha 7)
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import |
KPNA5 Genekaryopherin alpha 5 (importin alpha 6)
The transport |
KPNA4 Genekaryopherin alpha 4 (importin alpha 3)
The nuclear import |
KPNA3 Genekaryopherin alpha 3 (importin alpha 4)
The transport |
KPNA2 Genekaryopherin alpha 2 (RAG cohort 1, importin alpha 1)
The import |
KPNA1 Genekaryopherin alpha 1 (importin alpha 5)
The transport |
LOC100533843 Genekaryopherin alpha 2 (RAG cohort 1, importin alpha 1) pseudogene |
LOC402715 Genekaryopherin alpha 2 (RAG cohort 1, importin alpha 1) pseudogene |
PCBD2 Gene
pterin-4 alpha-carbinolamine dehydratase/dimerization c
Predicted to enable 4-alpha-hydroxytetrahydrobiopterin dehydratase activity. Involved in positive |
ST8SIA6 GeneST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
This gene encodes a member |
ST8SIA5 GeneST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
The protein encoded by this gene is a type II membrane protein that may be present in the Golgi apparatus. The encoded protein, which is a member |
ST8SIA4 GeneST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
The protein encoded by this gene catalyzes the polycondensation |
ST8SIA2 GeneST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer |
ST8SIA1 GeneST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth |
LOC643513 Genekaryopherin alpha 2 (RAG cohort 1, importin alpha 1) pseudogene |
LOC391798 Genekaryopherin alpha 7 (importin alpha 8) pseudogene |
PCBD1 Gene
pterin-4 alpha-carbinolamine dehydratase/dimerization c
This gene encodes a member |
DEFA1A3 Genedefensin, alpha 1 and alpha 3, variable copy number locus |
ST8SIA3 GeneST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
Enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity and identical protein binding activity. Involved in several processes, including ganglioside biosynthetic process; glycoprotein metabolic process; and sialylation. Predicted to be located in Golgi membrane. [provided by Alliance |
AGL Geneamylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range |
LOC100421109 Genekaryopherin alpha 4 (importin alpha 3) pseudogene |
ABO GeneABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
This gene encodes proteins related to the first discovered blood group system, ABO. Variation in the ABO gene (chromosome 9q34.2) is the basis |
CRTAM Genecytotoxic and regulatory T cell molecule The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009] |
MZB1 Genemarginal zone B and B1 cell-specific protein
Involved in positive |
SPDYE12P Genespeedy/RINGO cell cycle regulator family member E12, pseudogene
Predicted to enable protein kinase binding activity. [provided by Alliance |
LOC101060086 Genecell cycle exit and neuronal differentiation protein 1-like |
CDC27P10 Genecell division cycle 27 pseudogene 10 |
CDC27P11 Genecell division cycle 27 pseudogene 11 |
LOC100420540 Genecell division cycle associated 8 pseudogene |
BTG4 GeneB-cell translocation gene 4
The protein encoded by this gene is a member |
BTG1 GeneB-cell translocation gene 1, anti-proliferative
This gene is a member |
LOC101929185 Geneputative glycine-rich cell wall structural protein 1 |
MEMO1P4 Gene
mediator |
MEMO1P2 Gene
mediator |
MEMO1P3 Gene
mediator |
LOC728613 Geneprogrammed cell death 6 pseudogene |
MCL1 Genemyeloid cell leukemia 1
This gene encodes an anti-apoptotic protein, which is a member |
CEND1 Genecell cycle exit and neuronal differentiation 1 The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have been reported for this gene. [provided by RefSeq, Jul 2008] |
PCNA Geneproliferating cell nuclear antigen
The protein encoded by this gene is found in the nucleus and is a c |
BOC GeneBOC cell adhesion associated, oncogene regulated
The protein encoded by this gene is a member |
LOC100130203 Genecell adhesion associated, oncogene regulated pseudogene |
CDC34 Genecell division cycle 34
The protein encoded by this gene is a member |
CDC37 Genecell division cycle 37
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein |
BCL9 GeneB-cell CLL/lymphoma 9
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target |
BCL5 GeneB-cell CLL/lymphoma 5 |
BCL6 GeneB-cell CLL/lymphoma 6
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor |
BCL3 GeneB-cell CLL/lymphoma 3
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases |
BCL2 GeneB-cell CLL/lymphoma 2
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death |
HIRA Genehistone cell cycle regulator
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs |
INSL3 Geneinsulin-like 3 (Leydig cell)
This gene encodes a member |
LOC101929818 Genekiller cell immunoglobulin-like receptor 3DL1 |
KIR3DX1 Genekiller cell immunoglobulin-like receptor, three domains, X1
Predicted to be involved in immune response-regulating signaling pathway. Predicted to be located in extracellular region. Predicted to be active in plasma membrane. [provided by Alliance |
MNDA Genemyeloid cell nuclear differentiation antigen
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei |
TRGJ2 GeneT cell receptor gamma joining 2 |
TRGJ1 GeneT cell receptor gamma joining 1
Predicted to be involved in adaptive immune response. Predicted to be located in plasma membrane. Predicted to be part |
TRGJP GeneT cell receptor gamma joining P |
PCNAP1 Geneproliferating cell nuclear antigen pseudogene 1 |
PCNAP4 Geneproliferating cell nuclear antigen pseudogene 4 |
CDIP1 Genecell death-inducing p53 target 1
Predicted to enable zinc ion binding activity. Acts upstream |
LOC100287157 Genecell division cycle associated 8 pseudogene |
SCRIB Genescribbled planar cell polarity protein
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus |
TAGAP GeneT-cell activation RhoGTPase activating protein
This gene encodes a member |
NRCAM Geneneuronal cell adhesion molecule
Cell adhesion molecules (CAMs) are members |
MEMO1P1 Gene
mediator |
PDCD1LG2 Geneprogrammed cell death 1 ligand 2
Involved in negative |
DRAIC Gene
downregulated RNA in cancer, inhibitor |
TCTA GeneT-cell leukemia translocation altered
Involved in negative |
DELYQ11 GeneSertoli cell-only syndrome, Y-linked |
LOC100422623 Genecarcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) pseudogene |
ZYG11B Genezyg-11 family member B, cell cycle regulator
Involved in positive |
ZYG11A Genezyg-11 family member A, cell cycle regulator
Predicted to be part |
HK3 Genehexokinase 3 (white cell) Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. [provided by RefSeq, Apr 2009] |
CWH43 Genecell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
Predicted to be involved in GPI anchor biosynthetic process. Predicted to act upstream |
MTCP1 Genemature T-cell proliferation 1
This gene was identified by involvement in some t(X;14) translocations associated with mature T-cell proliferations. This region has a complex gene structure, with a common promoter and 5' exon spliced to two different sets |
CDCA2 Genecell division cycle associated 2
This gene encodes a targeting subunit |
CDCA3 Genecell division cycle associated 3
Predicted to be involved in cell division and protein ubiquitination. Located in adherens junction. [provided by Alliance |
CDCA7 Genecell division cycle associated 7
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression |
CDCA4 Genecell division cycle associated 4
This gene encodes a protein that belongs to the E2F family |
CDCA5 Genecell division cycle associated 5
Predicted to enable chromatin binding activity. Involved in chromosome organization; double-strand break repair; and positive |
CDCA8 Genecell division cycle associated 8
This gene encodes a component |
MUC4 Genemucin 4, cell surface associated
The major constituents |
NKS1 Genenatural killer cell susceptibility 1 |
CEMIP Genecell migration inducing protein, hyaluronan binding
Enables several functions, including clathrin heavy chain binding activity; hyaluronic acid binding activity; and hyalurononglucosaminidase activity. Involved in several processes, including hyaluronan catabolic process; positive |
EPCAM Geneepithelial cell adhesion molecule
This gene encodes a carcinoma-associated antigen and is a member |
RGCC Gene
regulator
This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels |
TCL6 GeneT-cell leukemia/lymphoma 6 (non-protein coding) |
TCL4 GeneT-cell leukemia/lymphoma 4 |
HMCES Gene5-hydroxymethylcytosine (hmC) binding, ES cell-specific
Enables DNA-(abasic site) binding activity; protein-DNA covalent cross-linking activity; and single-stranded DNA binding activity. Involved in interstrand cross-link repair; protein-DNA covalent cross-linking repair; and somatic hypermutation |
HCFC1R1 Genehost cell factor C1 regulator 1 (XPO1 dependent)
Located in nucleoplasm. [provided by Alliance |
MUC17 Genemucin 17, cell surface associated The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015] |
MUC16 Genemucin 16, cell surface associated
This gene encodes a protein that is a member |
MUC15 Genemucin 15, cell surface associated
Predicted to be located in Golgi lumen and plasma membrane. [provided by Alliance |
MUC13 Genemucin 13, cell surface associated
Epithelial mucins, such as MUC13, are a family |
MUC12 Genemucin 12, cell surface associated
This gene encodes an integral membrane glycoprotein that is a member |
HCC Genethyroid carcinoma, Hurthle cell |
NEDD8 Geneneural precursor cell expressed, developmentally down-regulated 8
Enables ubiquitin protein ligase binding activity. Acts upstream |
NEDD9 Geneneural precursor cell expressed, developmentally down-regulated 9
The protein encoded by this gene is a member |
NEDD1 Geneneural precursor cell expressed, developmentally down-regulated 1
Predicted to enable gamma-tubulin binding activity. Predicted to be involved in microtubule nucleation and mitotic cell cycle. Located in centrosome; cytosol; and nuclear lumen. [provided by Alliance |
HCLS1 Genehematopoietic cell-specific Lyn substrate 1
Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; protein kinase binding activity; and signaling adaptor activity. Involved in several processes, including granulocyte colony-stimulating factor signaling pathway; positive |
ERICD Gene
E2F1-regulated inhibitor |
TRGV5P GeneT cell receptor gamma variable 5P (pseudogene) |
PARD3 Genepar-3 family cell polarity regulator
This gene encodes a member |
LOC100132330 Genemal, T-cell differentiation protein-like pseudogene |
CD244 GeneCD244 molecule, natural killer cell receptor 2B4
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different is |
CPA3 Genecarboxypeptidase A3 (mast cell)
This gene encodes a member |
LIMS3L GeneLIM and senescent cell antigen-like domains 3-like
Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm; focal adhesion; and plasma membrane. [provided by Alliance |
TRGV10 GeneT cell receptor gamma variable 10 (non-functional)
Predicted to be involved in adaptive immune response. Predicted to be located in plasma membrane. Predicted to be part |
TCIRG1 GeneT-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
This gene encodes a subunit |
FRAT1 Genefrequently rearranged in advanced T-cell lymphomas 1
The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation |
FRAT2 Genefrequently rearranged in advanced T-cell lymphomas 2
The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator |
LOC105379645 Genekiller cell immunoglobulin-like receptor 2DL2 |
SDF2L1 Genestromal cell-derived factor 2-like 1
Enables misfolded protein binding activity. Involved in chaperone c |
LOC101060051 Genevegetative cell wall protein gp1-like |
BCC5 GeneBasal cell carcinoma, susceptibility to, 5 |
LOC105378167 Genevegetative cell wall protein gp1-like |
MCAM Genemelanoma cell adhesion molecule
Involved in glomerular filtration and vascular wound healing. Acts upstream |
KLRG1 Genekiller cell lectin-like receptor subfamily G, member 1
Natural killer (NK) cells are lymphocytes that can mediate lysis |
MCTS1 Genemalignant T cell amplified sequence 1
Enables RNA cap binding activity; ribosomal small subunit binding activity; and translation factor activity, non-nucleic acid binding. Involved in IRES-dependent viral translational initiation; cytoplasmic translational initiation; and ribosome disassembly. Is active in cytoplasm. Implicated in primary immunodeficiency disease. [provided by Alliance |
CCAR1 Genecell division cycle and apoptosis regulator 1
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; nuclear receptor coactivator activity; and transcription corepressor activity. Involved in positive |
CCAR2 Genecell cycle and apoptosis regulator 2
Enables RNA polymerase II complex binding activity and enzyme inhibitor activity. Involved in several processes, including mitochondrial fragmentation involved in apoptotic process; |
LOC100132609 Geneprogrammed cell death 2 pseudogene |
METRN Genemeteorin, glial cell differentiation regulator
Meteorin regulates glial cell differentiation and promotes the formation |
PCP4 GenePurkinje cell protein 4
Enables calcium ion binding activity and calmodulin binding activity. Involved in positive |
PCP2 GenePurkinje cell protein 2
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream |
CTAGE1 Genecutaneous T-cell lymphoma-associated antigen 1
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein secretion; and vesicle cargo loading. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum exit site and endoplasmic reticulum membrane. [provided by Alliance |
GMCL1P1 Genegerm cell-less, spermatogenesis associated 1 pseudogene 1
This locus shares a high degree |
GMCL1P2 Genegerm cell-less, spermatogenesis associated 1 pseudogene 2 |
KLRG2 Genekiller cell lectin-like receptor subfamily G, member 2
Predicted to enable carbohydrate binding activity. Predicted to be located in membrane. [provided by Alliance |
SCLC1 Gene
small cell cancer |
KLRB1 Genekiller cell lectin-like receptor subfamily B, member 1
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes |
CLLS2 GeneDisrupted in B-cell neoplasia |
MGCT Genemale germ cell tumor |
LOC105379650 Genekiller cell immunoglobulin-like receptor 2DS1 |
LOC101927245 Genevegetative cell wall protein gp1-like |
CIDECP Genecell death-inducing DFFA-like effector c pseudogene |
CDC20B Genecell division cycle 20B
Predicted to enable anaphase-promoting complex binding activity and ubiquitin ligase activator activity. Involved in de novo centriole assembly. Located in deuterosome. [provided by Alliance |
BCC6 GeneBasal cell carcinoma, susceptibility to, 6 |
VANGL1 GeneVANGL planar cell polarity protein 1
This gene encodes a member |
BCL6B GeneB-cell CLL/lymphoma 6, member B
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative |
SWAP70 GeneSWAP switching B-cell complex 70kDa subunit
Enables cadherin binding activity. Predicted to be involved in |
CDC5L Genecell division cycle 5-like
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator |
KIR2DS5 Genekiller cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
1060P11.3 Genekiller cell immunoglobulin-like receptor, three domains, pseudogene |
KIR2DS2 Genekiller cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
LOC105378775 Genecell death regulator Aven-like |
SPDYE10P Genespeedy/RINGO cell cycle regulator family member E10, pseudogene
Enables acetylcholine receptor regulator activity. [provided by Alliance |
FDCSP Genefollicular dendritic cell secreted protein
This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator |
EBF4 Geneearly B-cell factor 4
EBF4 belongs to the conserved Olf/EBF family |
EBF3 Geneearly B-cell factor 3
This gene encodes a member |
EBF2 Geneearly B-cell factor 2
The protein encoded by this gene belongs to the COE (Collier/Olf/EBF) family |
EBF1 Geneearly B-cell factor 1
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive |
CGRRF1 Genecell growth regulator with ring finger domain 1
Predicted to enable metal ion binding activity. Predicted to be involved in negative |
GLYCAM1 Geneglycosylation dependent cell adhesion molecule 1 (pseudogene)
Predicted to enable cell adhesion molecule binding activity and sulfate binding activity. Predicted to act upstream |
PP13 Genevegetative cell wall protein gp1 |
CDCA7L Genecell division cycle associated 7-like
Acts upstream |
TIGIT GeneT cell immunoreceptor with Ig and ITIM domains
This gene encodes a member |
MCIDAS Genemulticiliate differentiation and DNA synthesis associated cell cycle protein
This gene encodes a member |
NCR3LG1 Genenatural killer cell cytotoxicity receptor 3 ligand 1
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction |
KIR3DL1 Genekiller cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
KIR3DL2 Genekiller cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
KIR3DL3 Genekiller cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
MEMO1 Gene
mediator
Involved in |
BLID GeneBH3-like motif containing, cell death inducer This gene encodes a BH3-like motif containing protein involved in cell death. The encoded protein may induce apoptosis in a caspase-dependent manner. The protein is localized in both the cytoplasm and the mitochondrion. [provided by RefSeq, Aug 2011] |
ESAM Geneendothelial cell adhesion molecule
Enables cell-cell adhesion mediator activity. Involved in several processes, including bicellular tight junction assembly; cell-cell adhesion; and |
BANK1 GeneB-cell scaffold protein with ankyrin repeats 1
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation |
FUZ Genefuzzy planar cell polarity protein This gene encodes a planar cell polarity protein that is involved in ciliogenesis and directional cell movement. Knockout studies in mice exhibit neural tube defects and defective cilia, and mutations in this gene are associated with neural tube defects in humans. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012] |
CEACAM19 Genecarcinoembryonic antigen-related cell adhesion molecule 19
Predicted to be involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in membrane. Predicted to be active in cell surface. [provided by Alliance |
CEACAM18 Genecarcinoembryonic antigen-related cell adhesion molecule 18 |
CEACAM16 Genecarcinoembryonic antigen-related cell adhesion molecule 16
The protein encoded by this gene is a secreted glycoprotein that in mouse interacts with tectorial membrane proteins in the inner ear. The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range. Defects in this gene likely are a cause |
CIDEC Genecell death-inducing DFFA-like effector c
This gene encodes a member |
CIDEA Genecell death-inducing DFFA-like effector a
This gene encodes the homolog |
CDC42P5 Genecell division cycle 42 pseudogene 5 |
LOC105372844 Genevegetative cell wall protein gp1-like |
PBXIP1 Genepre-B-cell leukemia homeobox interacting protein 1
The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation |
PDCD6 Geneprogrammed cell death 6
This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple is |
PDCD7 Geneprogrammed cell death 7
This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component |
PDCD4 Geneprogrammed cell death 4 (neoplastic transformation inhibitor) This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] |
PDCD5 Geneprogrammed cell death 5
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator |
PDCD2 Geneprogrammed cell death 2
This gene encodes a nuclear protein expressed in a variety |
PDCD1 Geneprogrammed cell death 1
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the |
PDCD10 Geneprogrammed cell death 10
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause |
PDCD11 Geneprogrammed cell death 11
PDCD11 is a NF-kappa-B (NFKB1; 164011)-binding protein that colocalizes with U3 RNA (MIM 180710) in the nucleolus and is required for rRNA maturation and generation |
LOC345471 Genecell division cycle 37 homolog (S. cerevisiae) pseudogene |
MCF2 GeneMCF.2 cell line derived transforming sequence
The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members |
CDON Genecell adhesion associated, oncogene regulated
This gene encodes a cell surface receptor that is a member |
PPDPF Genepancreatic progenitor cell differentiation and proliferation factor
Predicted to be involved in cell differentiation. Predicted to act upstream |
LOC102725023 Genekiller cell immunoglobulin-like receptor 2DS3 allele 0020101 |
CDC20P1 Genecell division cycle 20 pseudogene 1 |
PDCD5P1 Geneprogrammed cell death 5 pseudogene 1 |
PDCD5P2 Geneprogrammed cell death 5 pseudogene 2 |
LIMS2 GeneLIM and senescent cell antigen-like domains 2
This gene encodes a member |
LIMS3 GeneLIM and senescent cell antigen-like domains 3
Predicted to enable metal ion binding activity. Predicted to be located in cytoplasm; focal adhesion; and plasma membrane. [provided by Alliance |
LIMS1 GeneLIM and senescent cell antigen-like domains 1
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery |
TRGJP2 GeneT cell receptor gamma joining P2 |
TRGJP1 GeneT cell receptor gamma joining P1 |
LOC102725210 Genevegetative cell wall protein gp1-like |
BOD1 Gene
biorientation
Enables protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Involved in mitotic sister chromatid biorientation; mitotic sister chromatid cohesion, centromeric; and protein localization to chromosome, centromeric region. Located in centrosome; spindle microtubule; and spindle pole. Part |
VTCN1 GeneV-set domain containing T cell activation inhibitor 1
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface |
CERCAM Genecerebral endothelial cell adhesion molecule
Enables identical protein binding activity. Acts upstream |
VCAM1 Genevascular cell adhesion molecule 1
This gene is a member |
LAKLG Genelymphokine-activated killer cell ligand |
NOS3 Genenitric oxide synthase 3 (endothelial cell)
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use |
TRDV1 GeneT cell receptor delta variable 1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRDV3 GeneT cell receptor delta variable 3
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRDV2 GeneT cell receptor delta variable 2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
URGCP Gene
upregulator
URG4 is upregulated in the presence |
SMAGP Genesmall cell adhesion glycoprotein
Located in cell junction; nucleoplasm; and plasma membrane. [provided by Alliance |
SPDYE15P Genespeedy/RINGO cell cycle regulator family member E15, pseudogene
Predicted to enable protein kinase binding activity. [provided by Alliance |
NCAM1 Geneneural cell adhesion molecule 1
This gene encodes a cell adhesion protein which is a member |
NCAM2 Geneneural cell adhesion molecule 2
The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein and may function in selective fasciculation and zone-to-zone projection |
KIR2DS4 Genekiller cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
KIR2DS3 Genekiller cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
KIR2DS1 Genekiller cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
CDC27P7 Genecell division cycle 27 pseudogene 7 |
LOC101930589 Genecell division cycle protein 27 homolog pseudogene |
CDC25C Genecell division cycle 25C
This gene encodes a conserved protein that plays a key role in the |
CDC25B Genecell division cycle 25B
CDC25B is a member |
CDC25A Genecell division cycle 25A
CDC25A is a member |
CDC27P2 Genecell division cycle 27 pseudogene 2 |
CDC27P3 Genecell division cycle 27 pseudogene 3 |
CDC27P1 Genecell division cycle 27 pseudogene 1 |
CDC27P6 Genecell division cycle 27 pseudogene 6 |
CDC27P4 Genecell division cycle 27 pseudogene 4 |
CDC27P5 Genecell division cycle 27 pseudogene 5 |
CDC27P8 Genecell division cycle 27 pseudogene 8 |
CDC27P9 Genecell division cycle 27 pseudogene 9 |
SPDYE2B Genespeedy/RINGO cell cycle regulator family member E2B
Predicted to enable protein kinase binding activity. [provided by Alliance |
HEPACAM Genehepatic and glial cell adhesion molecule
The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side |
TRGC1 GeneT cell receptor gamma constant 1
Enables small molecule binding activity. Predicted to be involved in T cell receptor signaling pathway; adaptive immune response; and gamma-delta T cell activation. Predicted to act upstream |
TRGC2 GeneT cell receptor gamma constant 2
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in T cell receptor signaling pathway and adaptive immune response. Predicted to be located in plasma membrane. Predicted to be part |
CDC27 Genecell division cycle 27
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product |
CDC26 Genecell division cycle 26
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component |
CDC20 Genecell division cycle 20 CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. [provided by RefSeq, Jul 2008] |
SPDYE8P Genespeedy/RINGO cell cycle regulator family member E8, pseudogene
Enables acetylcholine receptor regulator activity. [provided by Alliance |
BCAP31 GeneB-cell receptor-associated protein 31
This gene encodes a member |
NEDD4L Geneneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
This gene encodes a member |
THY1 GeneThy-1 cell surface antigen
This gene encodes a cell surface glycoprotein and member |
DAD1P1 Genedefender against cell death 1 pseudogene 1 |
PSHK2 GenePseudohyperkalemia, familial, 2, due to red cell leak |
CLNK Genecytokine-dependent hematopoietic cell linker
MIST is a member |
TCO GeneThyroid carcinoma, nonmedullary, with cell oxyphilia |
CDC14C Genecell division cycle 14C
This gene represents a retrogene |
CDC14B Genecell division cycle 14B
The protein encoded by this gene is a member |
CDC14A Genecell division cycle 14A
The protein encoded by this gene is a member |
CEACAM20 Genecarcinoembryonic antigen-related cell adhesion molecule 20
Predicted to enable protein tyrosine kinase binding activity. Predicted to be involved in |
CEACAM21 Genecarcinoembryonic antigen-related cell adhesion molecule 21
Predicted to be involved in T cell activation and immune response. Predicted to be located in membrane. Predicted to be active in external side |
LOC100420530 Genemucin 4, cell surface associated pseudogene |
LOC100420536 Geneislet cell autoantigen 1, 69kDa pseudogene |
LOC266683 Genedendritic cell protein pseudogene |
ICA1L Geneislet cell autoantigen 1,69kDa-like
Predicted to enable protein domain specific binding activity. Predicted to be involved in |
LOC101928242 Genecell cycle control protein 50B-like |
SPDYE7P Genespeedy/RINGO cell cycle regulator family member E7, pseudogene
Predicted to enable protein kinase binding activity. [provided by Alliance |
CDC23 Genecell division cycle 23
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component |
PRCC Genepapillary renal cell carcinoma (translocation-associated)
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion |
LOC391239 GeneV-set domain containing T cell activation inhibitor 1 pseudogene |
RQCD1 GeneRCD1 required for cell differentiation1 homolog (S. pombe)
This gene encodes a member |
LOC100128775 Geneneural precursor cell expressed, developmentally down-regulated 8 pseudogene |
BOD1L2 Gene
biorientation
Predicted to be involved in cell division. Predicted to be located in centrosome; cytoplasm; and kinetochore. [provided by Alliance |
BOD1L1 Gene
biorientation
Involved in DNA damage response and replication fork processing. Located in nucleoplasm. Part |
KLRAP1 Genekiller cell lectin-like receptor subfamily A pseudogene 1 |
PCNAP2 Geneproliferating cell nuclear antigen pseudogene 2 |
TCF7 Genetranscription factor 7 (T-cell specific, HMG-box)
This gene encodes a member |
LOC101409255 Genecell division cycle 42 pseudogene |
LOC101409256 Genecell division cycle 42 pseudogene |
PRG2 Geneproteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
The protein encoded by this gene is the predominant constituent |
MADCAM1 Genemucosal vascular addressin cell adhesion molecule 1
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member |
LOC100128686 Geneprogrammed cell death 10 pseudogene |
ICK Geneintestinal cell (MAK-like) kinase
Eukaryotic protein kinases are enzymes that belong to a very extensive family |
ZYG11AP1 Genezyg-11 family member A, cell cycle regulator pseudogene 1 |
NET1 Geneneuroepithelial cell transforming 1
This gene is part |
MCTS2P Genemalignant T cell amplified sequence 2, pseudogene
This locus represents a retrogene copy |
DSCAM GeneDown syndrome cell adhesion molecule
This gene is a member |
BCAP31P1 GeneB-cell receptor-associated protein 31 pseudogene 1 |
LOC100418583 Genemucin 4, cell surface associated pseudogene |
LOC100418585 Genemucin 4, cell surface associated pseudogene |
LOC100418584 Genemucin 4, cell surface associated pseudogene |
SCAI Gene
suppressor
This gene encodes a regulator |
SDK1 Genesidekick cell adhesion molecule 1
The protein encoded by this gene is a member |
SDK2 Genesidekick cell adhesion molecule 2
The protein encoded by this gene is a member |
PBX4 Genepre-B-cell leukemia homeobox 4
This gene encodes a member |
PBX2 Genepre-B-cell leukemia homeobox 2
This gene encodes a ubiquitously expressed member |
PBX3 Genepre-B-cell leukemia homeobox 3
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including eye development; nervous system development; and |
PBX1 Genepre-B-cell leukemia homeobox 1
This gene encodes a nuclear protein that belongs to the PBX homeobox family |
KIR3DS1 Genekiller cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
TAX1BP1 GeneTax1 (human T-cell leukemia virus type I) binding protein 1
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation |
TAX1BP3 GeneTax1 (human T-cell leukemia virus type I) binding protein 3
This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number |
CDC73 Genecell division cycle 73
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component |
TCAIM GeneT cell activation inhibitor, mitochondrial
Located in mitochondrion. [provided by Alliance |
AAMP Geneangio-associated, migratory cell protein
The gene is a member |
CDC26P1 Genecell division cycle 26 pseudogene 1 |
PARD6G Genepar-6 family cell polarity regulator gamma
Predicted to be involved in centrosome cycle; establishment or maintenance |
NCCRP1 Genenon-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
Predicted to contribute to ubiquitin protein ligase activity. Involved in positive |
MUC20 Genemucin 20, cell surface associated
This gene encodes a member |
MUC21 Genemucin 21, cell surface associated
This gene encodes a large membrane-bound glycoprotein which is a member |
LOC644070 Geneputative germ cell-specific gene 1-like protein 2
Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance |
ICOS Geneinducible T-cell co-stimulator
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and |
LOC132386 Geneepithelial cell adhesion molecule pseudogene |
LOC100129601 Genecell division cycle associated 7 pseudogene |
SPDYE11 Genespeedy/RINGO cell cycle regulator family member E11
Enables acetylcholine receptor regulator activity. [provided by Alliance |
TTIM1 GeneT-cell tumor invasion and metastasis 1 |
NKTR Genenatural killer cell triggering receptor
This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface |
LOC100128721 Genestromal cell-derived factor 2 pseudogene |
CHL1 Genecell adhesion molecule L1-like
The protein encoded by this gene is a member |
BCC4 GeneBasal cell carcinoma, susceptibility to, 4 |
TRDD3 GeneT cell receptor delta diversity 3
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRDD2 GeneT cell receptor delta diversity 2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRDD1 GeneT cell receptor delta diversity 1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
LOC102724621 Genecell division cycle protein 27 homolog pseudogene |
TRDC GeneT cell receptor delta constant
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
PSCA Geneprostate stem cell antigen
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion |
TRG-AS1 GeneT cell receptor gamma locus antisense RNA 1 |
ALCAM Geneactivated leukocyte cell adhesion molecule
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster |
HCST Genehematopoietic cell signal transducer
This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part |
SDF4 Genestromal cell derived factor 4
This gene encodes a stromal cell derived factor that is a member |
SDF2 Genestromal cell-derived factor 2
The protein encoded by this gene is believed to be a secretory protein. It has regions |
NKG7 Genenatural killer cell granule protein 7
Involved in defense response to protozoan. Located in cytolytic granule membrane and plasma membrane. [provided by Alliance |
GSG2 Genegerm cell associated 2 (haspin)
Enables ATP binding activity and histone H3T3 kinase activity. Involved in several processes, including mitotic sister chromatid cohesion; mitotic spindle assembly checkpoint signaling; and protein localization to chromosome, centromeric region. Located in centrosome; nucleoplasm; and spindle. [provided by Alliance |
GSG1 Genegerm cell associated 1
Predicted to enable RNA polymerase binding activity. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in plasma membrane. [provided by Alliance |
TRGV6 GeneT cell receptor gamma variable 6 (pseudogene) |
TRGV7 GeneT cell receptor gamma variable 7 (pseudogene) |
TRGV4 GeneT cell receptor gamma variable 4
Predicted to be involved in adaptive immune response and innate immune response. Predicted to be located in plasma membrane. Predicted to be part |
TRGV5 GeneT cell receptor gamma variable 5
Predicted to be involved in adaptive immune response and innate immune response. Predicted to be located in plasma membrane. Predicted to be part |
TRGV2 GeneT cell receptor gamma variable 2
Predicted to be involved in adaptive immune response and innate immune response. Predicted to be located in plasma membrane. Predicted to be part |
TRGV3 GeneT cell receptor gamma variable 3
Predicted to enable MHC protein binding activity and peptide antigen binding activity. Predicted to be involved in immune response. Predicted to be located in plasma membrane. Predicted to be part |
TRGV1 GeneT cell receptor gamma variable 1 (non-functional)
Predicted to be involved in adaptive immune response. Predicted to be located in plasma membrane. Predicted to be part |
TRGV8 GeneT cell receptor gamma variable 8
Predicted to be involved in adaptive immune response and innate immune response. Predicted to be located in plasma membrane. Predicted to be part |
TRGV9 GeneT cell receptor gamma variable 9
Predicted to enable MHC protein binding activity and peptide antigen binding activity. Predicted to be involved in adaptive immune response and innate immune response. Predicted to be located in plasma membrane. Predicted to be part |
TRGVB GeneT cell receptor gamma variable B (pseudogene) |
TRGVA GeneT cell receptor gamma variable A (pseudogene) |
TRAT1 GeneT cell receptor associated transmembrane adaptor 1
Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Acts upstream |
KIR2DL5B Genekiller cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
KIR2DL5A Genekiller cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
PECAM1 Geneplatelet/endothelial cell adhesion molecule 1
The protein encoded by this gene is found on the surface |
TAL1 GeneT-cell acute lymphocytic leukemia 1
Enables several functions, including E-box binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and histone deacetylase binding activity. Involved in several processes, including myeloid cell differentiation; positive |
TAL2 GeneT-cell acute lymphocytic leukemia 2
This intronless gene encodes a helix-loop-helix protein. Translocations between this gene on chromosome 9 and the T-cell receptor beta-chain locus on chromosome 7 have been associated with activation |
CDCA4P2 Genecell division cycle associated 4 pseudogene 2 |
PBX2P1 Genepre-B-cell leukemia homeobox 2 pseudogene 1 |
TLX1 GeneT-cell leukemia homeobox 1
This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily |
TLX2 GeneT-cell leukemia homeobox 2
This gene is a member |
TLX3 GeneT-cell leukemia homeobox 3 The protein encoded by this gene is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5;14)(q35;q32)] involving this gene is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults. [provided by RefSeq, Nov 2015] |
CDC37P1 Genecell division cycle 37 pseudogene 1 |
CDC37P2 Genecell division cycle 37 pseudogene 2 |
BCL7C GeneB-cell CLL/lymphoma 7C
This gene is identified by the similarity |
BCL7B GeneB-cell CLL/lymphoma 7B
This gene encodes a member |
BCL7A GeneB-cell CLL/lymphoma 7A
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result |
BTG1P1 GeneB-cell translocation gene 1 pseudogene 1 |
MSE Genemyelinating Schwann cell element |
GDNF Geneglial cell derived neurotrophic factor
This gene encodes a secreted ligand |
CDC45 Genecell division cycle 45
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation |
CDC40 Genecell division cycle 40 Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008] |
CDC42 Genecell division cycle 42
The protein encoded by this gene is a small GTPase |
TCL1B GeneT-cell leukemia/lymphoma 1B
Enables protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in intracellular signal transduction. [provided by Alliance |
TCL1A GeneT-cell leukemia/lymphoma 1A
Overexpression |
SPDYE13P Genespeedy/RINGO cell cycle regulator family member E13, pseudogene
Enables acetylcholine receptor regulator activity. [provided by Alliance |
LOC105379662 Genekiller cell immunoglobulin-like receptor 2DS1 |
LOC442172 Genecell division cycle associated 7 pseudogene |
SPDYE21P Genespeedy/RINGO cell cycle regulator family member E21, pseudogene
Predicted to enable protein kinase binding activity. [provided by Alliance |
ELMO2P1 Geneengulfment and cell motility 2 pseudogene 1 |
LOC100421663 Genecutaneous T-cell lymphoma-associated antigen 1 pseudogene |
LOC651644 GeneLIM and senescent cell antigen-like domains 2 pseudogene |
INTU Geneinturned planar cell polarity protein
Predicted to enable phosphatidylinositol binding activity. Involved in embryonic digit morphogenesis; ro |
LOC100129672 Genecell adhesion associated, oncogene regulated pseudogene |
TIAM1 GeneT-cell lymphoma invasion and metastasis 1
This gene encodes a RAC1-specific guanine nucleotide exchange factor (GEF). GEFs mediate the exchange |
TIAM2 GeneT-cell lymphoma invasion and metastasis 2
This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different is |
SART1 Genesquamous cell carcinoma antigen recognized by T cells
This gene encodes two proteins, the SART1(800) protein expressed in the nucleus |
CDC14BL GeneCDC14 cell division cycle 14 C-like |
SPDYE4 Genespeedy/RINGO cell cycle regulator family member E4
Predicted to enable protein kinase binding activity. [provided by Alliance |
BCL9P1 GeneB-cell CLL/lymphoma 9 pseudogene 1 |
TCF7L1 Genetranscription factor 7-like 1 (T-cell specific, HMG-box)
This gene encodes a member |
TCF7L2 Genetranscription factor 7-like 2 (T-cell specific, HMG-box)
This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants |
CDC123 Genecell division cycle 123
Enables ATP binding activity and magnesium ion binding activity. Involved in eukaryotic translation initiation factor 2 complex assembly. Located in cytoplasm. [provided by Alliance |
KLRD1 Genekiller cell lectin-like receptor subfamily D, member 1
Natural killer (NK) cells are a distinct lineage |
ELMO1 Geneengulfment and cell motility 1
This gene encodes a member |
ELMO2 Geneengulfment and cell motility 2
The protein encoded by this gene interacts with the dedicator |
ELMO3 Geneengulfment and cell motility 3
The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis |
CCPG1 Genecell cycle progression 1
Involved in positive |
MILR1 Genemast cell immunoglobulin-like receptor 1
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway; mast cell degranulation; and negative |
ECSCR Geneendothelial cell surface expressed chemotaxis and apoptosis regulator
The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation |
PDCD2L Geneprogrammed cell death 2-like
Predicted to be involved in apoptotic process. Located in membrane. [provided by Alliance |
DCANP1 Genedendritic cell-associated nuclear protein
This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One |
MUC1 Genemucin 1, cell surface associated
This gene encodes a membrane-bound protein that is a member |
CDCA4P4 Genecell division cycle associated 4 pseudogene 4 |
CDCA4P1 Genecell division cycle associated 4 pseudogene 1 |
CDCA4P3 Genecell division cycle associated 4 pseudogene 3 |
SPDYE22P Genespeedy/RINGO cell cycle regulator family member E22, pseudogene |
LOC100286895 Genecell division cycle 27 homolog pseudogene |
KLRK1 Genekiller cell lectin-like receptor subfamily K, member 1
Natural killer (NK) cells are lymphocytes that can mediate lysis |
BCC1 GeneBasal cell carcinoma, susceptibility to, 1 |
BCC2 GeneBasal cell carcinoma, susceptibility to, 2 |
BCC3 GeneBasal cell carcinoma, susceptibility to, 3 |
METRNL Genemeteorin, glial cell differentiation regulator-like
Predicted to enable hormone activity. Predicted to be involved in several processes, including brown fat cell differentiation; positive |
VANGL2 GeneVANGL planar cell polarity protein 2
The protein encoded by this gene is a membrane protein involved in the |
LOC728739 Geneprogrammed cell death 2 pseudogene |
TRD GeneT cell receptor delta locus |
TRG GeneT cell receptor gamma locus
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
CDC42P4 Genecell division cycle 42 pseudogene 4 |
CDC42P6 Genecell division cycle 42 pseudogene 6 |
CDC42P1 Genecell division cycle 42 pseudogene 1 |
CDC42P2 Genecell division cycle 42 pseudogene 2 |
LOC100421630 Genecutaneous T-cell lymphoma-associated antigen 1 pseudogene |
CEND1P1 Genecell cycle exit and neuronal differentiation 1 pseudogene 1 |
CEND1P2 Genecell cycle exit and neuronal differentiation 1 pseudogene 2 |
ECT2 Geneepithelial cell transforming 2
The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression |
TRDJ4 GeneT cell receptor delta joining 4
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRDJ1 GeneT cell receptor delta joining 1
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRDJ3 GeneT cell receptor delta joining 3
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
TRDJ2 GeneT cell receptor delta joining 2
T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface |
SPDYE14P Genespeedy/RINGO cell cycle regulator family member E14, pseudogene
Predicted to enable protein kinase binding activity. [provided by Alliance |
KLRC1 Genekiller cell lectin-like receptor subfamily C, member 1
Natural killer (NK) cells are lymphocytes that can mediate lysis |
KLRC3 Genekiller cell lectin-like receptor subfamily C, member 3
Natural killer (NK) cells are lymphocytes that can mediate lysis |
KLRC2 Genekiller cell lectin-like receptor subfamily C, member 2
Natural killer (NK) cells are lymphocytes that can mediate lysis |
KLRC4 Genekiller cell lectin-like receptor subfamily C, member 4
Natural killer (NK) cells are lymphocytes that can mediate lysis |
MALL Genemal, T-cell differentiation protein-like
This gene encodes an element |
MAL2 Genemal, T-cell differentiation protein 2 (gene/pseudogene)
This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component |
MCF2L GeneMCF.2 cell line derived transforming sequence-like This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
LOC105376731 Genetaste receptor cell protein 1-like |
ZER1 Genezyg-11 related, cell cycle regulator
This gene encodes a subunit |
LOC100288590 Genecutaneous T-cell lymphoma-associated antigen 1 pseudogene |
LOC100967224 Geneneuroepithelial cell transforming 1 pseudogene |
LOC100967223 Geneneuroepithelial cell transforming 1 pseudogene |
BAD Gene
BCL2-associated agonist
The protein encoded by this gene is a member |
HCFC2P1 Genehost cell factor C2 pseudogene 1 |
MCEMP1 Genemast cell-expressed membrane protein 1 This gene encodes a single-pass transmembrane protein. Based on its expression pattern, it is speculated to be involved in regulating mast cell differentiation or immune responses. [provided by RefSeq, Jul 2008] |
CDC16 Genecell division cycle 16
The protein encoded by this gene functions as a protein ubiquitin ligase and is a component |
BCAP29 GeneB-cell receptor-associated protein 29
Involved in osteoblast differentiation. Located in membrane. [provided by Alliance |
ECT2L Geneepithelial cell transforming 2 like
Predicted to enable guanyl-nucleotide exchange factor activity. [provided by Alliance |
SPDYE9P Genespeedy/RINGO cell cycle regulator family member E9, pseudogene
Enables acetylcholine receptor regulator activity. [provided by Alliance |
SPDYE5 Genespeedy/RINGO cell cycle regulator family member E5
Predicted to enable protein kinase binding activity. Predicted to be involved in positive |
SPDYE6 Genespeedy/RINGO cell cycle regulator family member E6
This gene encodes a cell cycle regulatory protein which plays an important role in cell cycle progression by binding and activating cyclin-dependent kinases. The encoded protein belongs to a family |
SPDYE1 Genespeedy/RINGO cell cycle regulator family member E1 This gene is located at chromosome 7p13 which is close to the Williams Beuren syndrome chromosome region 7q11.23. [provided by RefSeq, Jul 2008] |
SPDYE3 Genespeedy/RINGO cell cycle regulator family member E3
Predicted to enable protein kinase binding activity. [provided by Alliance |
SPDYE2 Genespeedy/RINGO cell cycle regulator family member E2
Predicted to enable protein kinase binding activity. [provided by Alliance |
ERAS GeneES cell expressed Ras
This gene encodes a constitutively active member |
TGCT1 Genetesticular germ cell tumor susceptibility 1 |
ICA1 Geneislet cell autoantigen 1, 69kDa
This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different is |
LOC100420644 Genecell division cycle associated 8 pseudogene |
CDC6 Genecell division cycle 6
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation |
CDC7 Genecell division cycle 7
This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation |
CEACAMP10 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 10 |
CEACAMP11 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 11 |
ITK GeneIL2-inducible T-cell kinase
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are |
BCL9L GeneB-cell CLL/lymphoma 9-like
Enables beta-catenin binding activity. Involved in several processes, including negative |
SPDYE18 Genespeedy/RINGO cell cycle regulator family member E18
Predicted to enable protein kinase binding activity. [provided by Alliance |
ESM1 Geneendothelial cell-specific molecule 1
This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression |
MAK Genemale germ cell-associated kinase
The product |
MAL Genemal, T-cell differentiation protein
The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family |
CDC37L1 Genecell division cycle 37-like 1 CDC37L1 is a cytoplasmic phosphoprotein that exists in complex with HSP90 (HSPCA; MIM 140571) as well as several other proteins involved in HSP90-mediated protein folding (Scholz et al., 2001 [PubMed 11413142]).[supplied by OMIM, Mar 2008] |
CEACAMP8 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 8 |
CEACAMP9 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 9 |
CEACAMP2 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 2 |
CEACAMP3 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 3 |
CEACAMP1 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 1 |
CEACAMP6 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 6 |
CEACAMP7 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 7 |
CEACAMP4 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 4 |
CEACAMP5 Genecarcinoembryonic antigen-related cell adhesion molecule pseudogene 5 |
LOC105369139 Genekiller cell immunoglobulin-like receptor 2DS3 |
PCNAP3 Geneproliferating cell nuclear antigen pseudogene 3 |
LOC100420949 Geneneuroepithelial cell transforming 1 pseudogene |
ICOSLG Geneinducible T-cell co-stimulator ligand
Enables identical protein binding activity and receptor ligand activity. Involved in T follicular helper cell differentiation. Located in intracellular membrane-bounded organelle. Is active in plasma membrane. [provided by Alliance |
DSCAML1 GeneDown syndrome cell adhesion molecule like 1
The protein encoded by this gene is a member |
CIDEB Genecell death-inducing DFFA-like effector b
Enables identical protein binding activity. Involved in lipid droplet fusion and positive |
CEACAM22P Genecarcinoembryonic antigen-related cell adhesion molecule 22, pseudogene |
TP250 GeneT-cell activation antigen p250 |
MCF2L2 GeneMCF.2 cell line derived transforming sequence-like 2
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in cytosol. Predicted to be active in cytoplasm. [provided by Alliance |
CGREF1 Genecell growth regulator with EF-hand domain 1
Predicted to enable calcium ion binding activity. Predicted to be involved in negative |
LOC651714 Genemucin 20, cell surface associated pseudogene |
BCL10 GeneB-cell CLL/lymphoma 10
This gene was identified by its translocation in a case |
L1CAM GeneL1 cell adhesion molecule
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting |
TS546 GeneTemperature sensitivity complementation, cell cycle specific |
CAPRIN1 Genecell cycle associated protein 1
Enables several functions, including ATP binding activity; molecular condensate scaffold activity; and signaling adaptor activity. Involved in membraneless organelle assembly; positive |
ESRG Geneembryonic stem cell related (non-protein coding)
Part |
KLRF2 Genekiller cell lectin-like receptor subfamily F, member 2
Enables protein homodimerization activity. Predicted to be involved in natural killer cell degranulation and positive |
KLRF1 Genekiller cell lectin-like receptor subfamily F, member 1 KLRF1, an activating homodimeric C-type lectin-like receptor (CTLR), is expressed on nearly all natural killer (NK) cells and stimulates their cytoxicity and cytokine release (Kuttruff et al., 2009 [PubMed 18922855]).[supplied by OMIM, Oct 2009] |
SPDYE19P Genespeedy/RINGO cell cycle regulator family member E19, pseudogene |
FAS GeneFas cell surface death receptor
The protein encoded by this gene is a member |
SART3 Genesquamous cell carcinoma antigen recognized by T cells 3
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable |
LECT1 Geneleukocyte cell derived chemotaxin 1
This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus |
LECT2 Geneleukocyte cell-derived chemotaxin 2
This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth |
OPCML Geneopioid binding protein/cell adhesion molecule-like
This gene encodes a member |
WDPCP GeneWD repeat containing planar cell polarity effector This gene encodes a cytoplasmic WD40 repeat protein. A similar gene in frogs encodes a planar cell polarity protein that plays a critical role in collective cell movement and ciliogenesis by mediating septin localization. Mutations in this gene are associated with Bardet-Biedl syndrome 15 and may also play a role in Meckel-Gruber syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
LOC440059 Genecell adhesion associated, oncogene regulated pseudogene |
SPDYE17 Genespeedy/RINGO cell cycle regulator family member E17
Enables acetylcholine receptor regulator activity. [provided by Alliance |
SPDYE16 Genespeedy/RINGO cell cycle regulator family member E16
Predicted to enable protein kinase binding activity. [provided by Alliance |
SPDYA Genespeedy/RINGO cell cycle regulator family member A
Enables protein kinase activator activity and protein kinase binding activity. Involved in several processes, including G1/S transition |
SPDYC Genespeedy/RINGO cell cycle regulator family member C
Enables protein kinase binding activity. Predicted to be located in nucleus. [provided by Alliance |
BLACE GeneB-cell acute lymphoblastic leukemia expressed |
LOC100131557 Geneprogrammed cell death 2-like pseudogene |
LOC100128800 Genecell adhesion associated, oncogene regulated pseudogene |
KIR3DP1 Genekiller cell immunoglobulin-like receptor, three domains, pseudogene 1
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
SENCR Genesmooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA |
BLNK GeneB-cell linker
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation |
TARM1 GeneT cell-interacting, activating receptor on myeloid cells 1
Enables immunoglobulin receptor binding activity. Involved in negative |
TIMD4 GeneT-cell immunoglobulin and mucin domain containing 4
Predicted to enable phosphatidylserine binding activity. Predicted to be involved in apoptotic cell clearance and cytoskeletal rearrangement involved in phagocytosis, engulfment. Predicted to be located in extracellular region and plasma membrane. [provided by Alliance |
LOC100420144 Gene
mediator |
MUC3A Genemucin 3A, cell surface associated
The mucin genes encode epithelial glycoproteins, some |
MUC3B Genemucin 3B, cell surface associated
Predicted to be located in Golgi lumen and plasma membrane. [provided by Alliance |
DAD1 Genedefender against cell death 1
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator |
HCFC2 Genehost cell factor C2
This gene encodes one |
HCFC1 Genehost cell factor C1
This gene is a member |
BCAP31P2 GeneB-cell receptor-associated protein 31 pseudogene 2 |
MS4A3 Genemembrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
This gene encodes a member |
KIR2DP1 Genekiller cell immunoglobulin-like receptor, two domains, pseudogene 1
Predicted to be involved in immune response-regulating signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance |
TCAM1P Genetesticular cell adhesion molecule 1, pseudogene
This pseudogene is located downstream from the growth hormone locus on chromosome 17. This locus evolved by a series |
BST1 Genebone marrow stromal cell antigen 1 Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population. [provided by RefSeq, Jul 2008] |
BST2 Genebone marrow stromal cell antigen 2
Bone marrow stromal cells are involved in the growth and development |
PCP4L1 GenePurkinje cell protein 4 like 1 |
PDCD6IP Geneprogrammed cell death 6 interacting protein
This gene encodes a protein that functions within the ESCRT pathway in the abscission stage |
FCP1 GeneF-cell production 1 |
TRGV11 GeneT cell receptor gamma variable 11 (non-functional)
Predicted to be involved in adaptive immune response. Predicted to be located in external side |
NEDD4 Geneneural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
This gene is the founding member |
SPDYE20P Genespeedy/RINGO cell cycle regulator family member E20, pseudogene |
UTF1 Geneundifferentiated embryonic cell transcription factor 1
The protein encoded by this gene is a leucine zipper-containing transcriptional coactivator that may link the upstream activator ATF2 with the basal transcription complex. The encoded protein is closely associated with chromatin and is required for the proper differentiation |
CEACAM1 Genecarcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
This gene encodes a member |
CEACAM3 Genecarcinoembryonic antigen-related cell adhesion molecule 3
This gene encodes a member |
CEACAM5 Genecarcinoembryonic antigen-related cell adhesion molecule 5
This gene encodes a cell surface glycoprotein that represents the founding member |
CEACAM4 Genecarcinoembryonic antigen-related cell adhesion molecule 4
Predicted to enable protein tyrosine kinase binding activity. Involved in phagocytosis. Predicted to be located in membrane. Predicted to be active in cell surface and plasma membrane. [provided by Alliance |
CEACAM7 Genecarcinoembryonic antigen-related cell adhesion molecule 7
This gene encodes a cell surface glycoprotein and member |
CEACAM6 Genecarcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members |
CEACAM8 Genecarcinoembryonic antigen-related cell adhesion molecule 8
Enables protein heterodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in cell surface and extracellular space. Biomarker |
HIRAP1 Genehistone cell cycle regulator pseudogene 1 |
CDC42P3 Genecell division cycle 42 pseudogene 3 |
BCAM Genebasal cell adhesion molecule (Lutheran blood group)
This gene encodes Lutheran blood group glycoprotein, a member |
CWF19L1 GeneCWF19-like 1, cell cycle control (S. pombe)
This gene encodes a member |
CWF19L2 GeneCWF19-like 2, cell cycle control (S. pombe)
Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleoplasm. Predicted to be part |
KIR2DL3 Genekiller cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
KIR2DL2 Genekiller cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
KIR2DL1 Genekiller cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
KIR2DL4 Genekiller cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets |
LOC100422671 Genecell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) pseudogene |
GMCL1 Genegerm cell-less, spermatogenesis associated 1
This gene encodes a nuclear envelope protein that appears to be involved in spermatogenesis, either directly or by influencing genes that play a more direct role in the process. This multi-exon locus is the homolog |
CADM4 Genecell adhesion molecule 4
Enables vascular endothelial growth factor receptor 2 binding activity. Involved in several processes, including negative |
CADM2 Genecell adhesion molecule 2
This gene encodes a member |
CADM3 Genecell adhesion molecule 3 The protein encoded by this gene is a calcium-independent cell-cell adhesion protein that can form homodimers or heterodimers with other nectin proteins. The encoded protein has both homophilic and heterophilic cell-cell adhesion activity. This gene is reported to be a tumor suppressor gene. [provided by RefSeq, Oct 2016] |
CADM1 Genecell adhesion molecule 1
Enables signaling receptor binding activity. Involved in several processes, including cell recognition; positive |
LOC101927197 Genecell death activator CIDE-3-like |
LOC105369971 Genevegetative cell wall protein gp1-like |
CMA1 Genechymase 1, mast cell
This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation |
BCL11A GeneB-cell CLL/lymphoma 11A (zinc finger protein)
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site |
BCL11B GeneB-cell CLL/lymphoma 11B (zinc finger protein)
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function |
BOD1P2 Gene
biorientation |
BOD1P1 Gene
biorientation |
NKCD GeneNatural killer cell deficiency, familial isolated |
LOC101409262 Genecell division cycle 42 pseudogene |
FZR1 Genefizzy/cell division cycle 20 related 1 (Drosophila)
Enables ubiquitin-like ligase-substrate adaptor activity. Involved in anaphase-promoting complex-dependent catabolic process; mitotic G2 DNA damage checkpoint signaling; and positive |
RIPOR1 GeneRHO family interacting cell polarization regulator 1
Enables 14-3-3 protein binding activity. Involved in several processes, including establishment |
NECTIN1 Genenectin cell adhesion molecule 1
This gene encodes an adhesion protein that plays a role in the organization |
CEMIP2 Genecell migration inducing hyaluronidase 2
This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation |
NECTIN4 Genenectin cell adhesion molecule 4
This gene encodes a member |
NECTIN2 Genenectin cell adhesion molecule 2
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one |
PATJ GenePATJ crumbs cell polarity complex component
This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains |
NECTIN3 Genenectin cell adhesion molecule 3
This gene encodes a member |
RIPOR2 GeneRHO family interacting cell polarization regulator 2
This gene encodes an atypical inhibitor |
ALPG Genealkaline phosphatase, germ cell
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product |
GMCL2 Genegerm cell-less 2, spermatogenesis associated
This locus shares a high degree |
CYREN Gene
cell cycle regulator
Predicted to enable molecular adaptor activity. Involved in double-strand break repair via nonhomologous end joining and negative |
DELE1 GeneDAP3 binding cell death enhancer 1
Enables protein kinase binding activity and protein serine/threonine kinase activator activity. Involved in several processes, including HRI-mediated signaling; positive |
SPDYE9 Genespeedy/RINGO cell cycle regulator family member E9
Enables acetylcholine receptor regulator activity. [provided by Alliance |
PPDPFL Genepancreatic progenitor cell differentiation and proliferation factor like
Predicted to be involved in cell differentiation. [provided by Alliance |
SPDYE10 Genespeedy/RINGO cell cycle regulator family member E10
Enables acetylcholine receptor regulator activity. [provided by Alliance |
GCNA Genegerm cell nuclear acidic peptidase
Enables SUMO polymer binding activity. Involved in protein-DNA covalent cross-linking repair. Located in PML body. Implicated in X-linked spermatogenic failure 4. [provided by Alliance |
SPDYE21 Genespeedy/RINGO cell cycle regulator family member E21
Predicted to enable protein kinase binding activity. [provided by Alliance |
RHEX Gene
regulator
Enables erythropoietin receptor binding activity. Involved in erythropoietin-mediated signaling pathway and positive |
SPDYE12 Genespeedy/RINGO cell cycle regulator family member E12
Predicted to enable protein kinase binding activity. [provided by Alliance |
KLRA1P Genekiller cell lectin like receptor A1, pseudogene |
NALT1 GeneNOTCH1 associated lncRNA in T cell acute lymphoblastic leukemia 1 |
CIDECP1 Genecell death inducing DFFA like effector c pseudogene 1 |
MUC20P1 Genemucin 20, cell surface associated pseudogene 1 |
PICSAR GeneP38 inhibited cutaneous squamous cell carcinoma associated lincRNA |
NICOL1 GeneNELL2 interacting cell ontogeny regulator 1
Predicted to enable mRNA 3'-UTR binding activity. Predicted to be involved in 3'-UTR-mediated mRNA stabilization and spermatogenesis. Predicted to be located in perinuclear region |
LCDR Genelysosome cell death regulator |
SCIRT Genestem cell inhibitory RNA transcript |
SPDYE13 Genespeedy/RINGO cell cycle regulator family member E13
Enables acetylcholine receptor regulator activity. [provided by Alliance |
SPDYE8 Genespeedy/RINGO cell cycle regulator family member E8
Enables acetylcholine receptor regulator activity. [provided by Alliance |
SPDYE14 Genespeedy/RINGO cell cycle regulator family member E14
Predicted to enable protein kinase binding activity. [provided by Alliance |
CDC50A Genecell division cycle 50 P4-ATPase accessory subunit A
Enables aminophospholipid flippase activity and structural molecule activity. Involved in several processes, including phospholipid transport; positive |
CDC50B Genecell division cycle 50 P4-ATPase accessory subunit B
Enables aminophospholipid flippase activity. Involved in aminophospholipid transport and positive |
LOC112268354 Genekiller cell immunoglobulin-like receptor 2DL4-like |
LOC643634 Genetropomyosin 1 (alpha) pseudogene |
ITGA8 Geneintegrin, alpha 8
Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation |
ITGA9 Geneintegrin, alpha 9
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed |
ITGA1 Geneintegrin, alpha 1
This gene encodes the alpha 1 subunit |
ITGA6 Geneintegrin, alpha 6
The gene encodes a member |
ITGA7 Geneintegrin, alpha 7
The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed |
ITGAX Geneintegrin, alpha X (complement component 3 receptor 4 subunit)
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed |
ITGAV Geneintegrin, alpha V
The product |
ITGAM Geneintegrin, alpha M (complement component 3 receptor 3 subunit)
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed |
ITGAD Geneintegrin, alpha D
This gene belongs to the beta-2 integrin family |
AAGAB Genealpha- and gamma-adaptin binding protein
The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits |
PRKAR2A Geneprotein kinase, cAMP-dependent, regulatory, type II, alpha
cAMP is a signaling molecule important for a variety |
ITGA2B Gene
integrin, alpha 2b (platelet glycoprotein IIb
This gene encodes a member |
LOC105378951 Genecollagen alpha-1(III) chain-like |
LOC101930347 Genecollagen alpha-2(I) chain-like |
NDUFA3P3 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 pseudogene 3 |
CAMKK1 Genecalcium/calmodulin-dependent protein kinase kinase 1, alpha
The product |
SEC61A1 GeneSec61 alpha 1 subunit (S. cerevisiae)
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion |
SEC61A2 GeneSec61 alpha 2 subunit (S. cerevisiae)
The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion |
FCER1A Gene
Fc fragment
The immunoglobulin epsilon receptor (IgE receptor) is the initiator |
SRD5A3 Genesteroid 5 alpha-reductase 3
The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production |
COL14A1 Genecollagen, type XIV, alpha 1
This gene encodes the alpha chain |
PPP3CA Geneprotein phosphatase 3, catalytic subunit, alpha isozyme
Enables several functions, including ATPase binding activity; calmodulin binding activity; and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; negative |
ADRA2A Geneadrenoceptor alpha 2A
Alpha-2-adrenergic receptors are members |
ADRA2B Geneadrenoceptor alpha 2B
This intronless gene encodes a seven-pass transmembrane protein. This protein is a member |
ADRA2C Geneadrenoceptor alpha 2C
Alpha-2-adrenergic receptors are members |
ENO1 Geneenolase 1, (alpha)
This gene encodes alpha-enolase, one |
LMX1A GeneLIM homeobox transcription factor 1, alpha
This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator |
ANKS1B Geneankyrin repeat and sterile alpha motif domain containing 1B
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis |
ANKS1A Geneankyrin repeat and sterile alpha motif domain containing 1A
Predicted to enable ephrin receptor binding activity. Predicted to be involved in ephrin receptor signaling pathway; neuron remodeling; and substrate-dependent cell migration. Predicted to act upstream |
LOC730222 Genetubulin, alpha 3d pseudogene |
ATP7A GeneATPase, Cu++ transporting, alpha polypeptide
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions |
SAMD4A Genesterile alpha motif domain containing 4A
Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part |
SAMD4B Genesterile alpha motif domain containing 4B
Enables RNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream |
PCDHAC2 Geneprotocadherin alpha subfamily C, 2
This gene is a member |
PCDHAC1 Geneprotocadherin alpha subfamily C, 1
This gene is a member |
PCDHACT Geneprotocadherin alpha constant
The genomic organization |
MCCC1 Genemethylcrotonoyl-CoA carboxylase 1 (alpha)
This gene encodes the large subunit |
ACACA Geneacetyl-CoA carboxylase alpha
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation |
LOC100129096 Genetropomyosin 1 (alpha) pseudogene |
REG1A Generegenerating islet-derived 1 alpha
This gene is a type I subclass member |
DAGLA Genediacylglycerol lipase, alpha
This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis |
CSNK1A1L Genecasein kinase 1, alpha 1-like
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in negative |
LOC731755 Geneeukaryotic translation initiation factor 2-alpha kinase 1 pseudogene |
ACTN3 Geneactinin, alpha 3 (gene/pseudogene)
This gene encodes a member |
ACTN2 Geneactinin, alpha 2
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group |
ACTN1 Geneactinin, alpha 1
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group |
ACTN4 Geneactinin, alpha 4
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group |
LOC340268 GeneC3 and PZP-like, alpha-2-macroglobulin domain containing 8 pseudogene |
SPTA1 Genespectrin, alpha, erythrocytic 1
This gene encodes a member |
HGSNAT Geneheparan-alpha-glucosaminide N-acetyltransferase
This gene encodes a lysosomal acetyltransferase, which is one |
PPFIA4 Geneprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 PPFIA4, or liprin-alpha-4, belongs to the liprin-alpha gene family. See liprin-alpha-1 (LIP1, or PPFIA1; MIM 611054) for background on liprins.[supplied by OMIM, Mar 2008] |
ALG8 GeneALG8, alpha-1,3-glucosyltransferase
This gene encodes a member |
ALG2 GeneALG2, alpha-1,3/1,6-mannosyltransferase
This gene encodes a member |
ALG3 GeneALG3, alpha-1,3- mannosyltransferase
This gene encodes a member |
ALG6 GeneALG6, alpha-1,3-glucosyltransferase
This gene encodes a member |
LOC100421817 Geneeukaryotic translation elongation factor 1 alpha 2 pseudogene |
NDUFA3P1 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 pseudogene 1 |
ESRRAP2 Geneestrogen-related receptor alpha pseudogene 2 |
ESRRAP1 Geneestrogen-related receptor alpha pseudogene 1 |
TUBA1C Genetubulin, alpha 1c
Predicted to enable GTP binding activity. Predicted to be a structural constituent |
TUBA1B Genetubulin, alpha 1b
Enables several functions, including GTP binding activity; GTPase activity; and ubiquitin protein ligase binding activity. A structural constituent |
TUBA1A Genetubulin, alpha 1a
Microtubules |
LOC105369637 Genecollagen alpha-1(I) chain-like |
HSP90AA3P Geneheat shock protein 90kDa alpha (cytosolic), class A member 3, pseudogene |
EEF1A1 Geneeukaryotic translation elongation factor 1 alpha 1
This gene encodes an is |
EEF1A2 Geneeukaryotic translation elongation factor 1 alpha 2
This gene encodes an is |
NFYA Genenuclear transcription factor Y, alpha
The protein encoded by this gene is one subunit |
GPHA2 Geneglycoprotein hormone alpha 2
GPHA2 is a cystine knot-forming polypeptide and a subunit |
PAM Genepeptidylglycine alpha-amidating monooxygenase
This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion |
THRA Genethyroid hormone receptor, alpha
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one |
PDHA2 Genepyruvate dehydrogenase (lipoamide) alpha 2
Enables pyruvate dehydrogenase (NAD+) activity and pyruvate dehydrogenase (acetyl-transferring) activity. Involved in pyruvate metabolic process. Located in mitochondrion and nucleolus. Implicated in spermatogenic failure 70. [provided by Alliance |
PDHA1 Genepyruvate dehydrogenase (lipoamide) alpha 1
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion |
EEF1A1P19 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 19 |
EEF1A1P18 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 18 |
EEF1A1P10 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 10 |
EEF1A1P15 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 15 |
LOC105370705 Genecollagen alpha-2(I) chain-like |
COL27A1 Genecollagen, type XXVII, alpha 1
This gene encodes a member |
DEFA1B Genedefensin, alpha 1B
Defensins are a family |
SCN1A Genesodium channel, voltage gated, type I alpha subunit
Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation |
EEF1A1P35 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 35 |
EEF1A1P31 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 31 |
EEF1A1P33 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 33 |
EEF1A1P39 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 39 |
EEF1A1P38 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 38 |
LOC644661 Geneimportin subunit alpha-1 pseudogene |
LOC101060328 Genecollagen alpha-1(I) chain-like |
NACA Genenascent polypeptide-associated complex alpha subunit
This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature |
SIRPAP1 Genesignal-regulatory protein alpha pseudogene 1 |
SI Genesucrase-isomaltase (alpha-glucosidase)
This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion |
IFNA21 Geneinterferon, alpha 21
This gene is a member |
DEFA4 Genedefensin, alpha 4, corticostatin
Defensins are a family |
DEFA3 Genedefensin, alpha 3, neutrophil-specific
Defensins are a family |
DEFA1 Genedefensin, alpha 1
Defensins are a family |
GSTA4 Geneglutathione S-transferase alpha 4
Cytosolic and membrane-bound forms |
GSTA5 Geneglutathione S-transferase alpha 5
The glutathione S-transferases (GST; EC 2.5.1.18) catalyze the conjugation |
GSTA1 Geneglutathione S-transferase alpha 1
This gene encodes a member |
GSTA2 Geneglutathione S-transferase alpha 2
Cytosolic and membrane-bound forms |
GSTA3 Geneglutathione S-transferase alpha 3
Cytosolic and membrane-bound forms |
PROS1 Geneprotein S (alpha)
This gene encodes a vitamin K-dependent plasma protein that functions as a c |
LOC644436 Genetubulin, alpha 4a pseudogene |
GFRAL GeneGDNF family receptor alpha like
Enables glial cell-derived neurotrophic factor receptor activity and receptor tyrosine kinase binding activity. Involved in GDF15-GFRAL signaling pathway; positive |
LOC100421126 Genesucrase-isomaltase (alpha-glucosidase) pseudogene |
SCNN1A Genesodium channel, non voltage gated 1 alpha subunit
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting |
LOC100422479 Geneintegrin, alpha X (complement component 3 receptor 4 subunit) pseudogene |
NAA50 GeneN(alpha)-acetyltransferase 50, NatE catalytic subunit
Enables histone H4 acetyltransferase activity and peptide alpha-N-acetyltransferase activity. Involved in N-terminal protein amino acid acetylation; establishment |
COL9A2 Genecollagen, type IX, alpha 2
This gene encodes one |
COL9A3 Genecollagen, type IX, alpha 3
This gene encodes one |
COL9A1 Genecollagen, type IX, alpha 1
This gene encodes one |
HBHR Genealpha-thalassemia/mental retardation syndrome, type 1 |
LOC100420255 Genecollagen, type XXII, alpha 1 pseudogene |
DEFA9P Genedefensin, alpha 9 pseudogene |
MAT1A Genemethionine adenosyltransferase I, alpha
This gene catalyzes a two-step reaction that involves the transfer |
FGA Genefibrinogen alpha chain
This gene encodes the alpha subunit |
ZAK Genesterile alpha motif and leucine zipper containing kinase AZK
This gene is a member |
SNCAIP Genesynuclein, alpha interacting protein
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation |
SCN9A Genesodium channel, voltage gated, type IX alpha subunit This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009] |
EEF1A1P9 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 9 |
EEF1A1P8 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 8 |
EEF1A1P7 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 7 |
EEF1A1P6 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 6 |
EEF1A1P5 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 5
Predicted to enable GTPase activity and translation elongation factor activity. Predicted to be involved in translational elongation. Located in extracellular exosome and nucleus. [provided by Alliance |
EEF1A1P4 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 4 |
EEF1A1P3 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 3 |
EEF1A1P2 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 2 |
EEF1A1P1 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 1 |
GADD45A Genegrowth arrest and DNA-damage-inducible, alpha
This gene is a member |
ITGA10 Geneintegrin, alpha 10
Integrins are integral transmembrane glycoproteins composed |
ITGA11 Geneintegrin, alpha 11
This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed |
HLA-DOA Genemajor histocompatibility complex, class II, DO alpha HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] |
C8A Genecomplement component 8, alpha polypeptide
C8 is a component |
HLA-DQA1 Genemajor histocompatibility complex, class II, DQ alpha 1
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting |
HLA-DQA2 Genemajor histocompatibility complex, class II, DQ alpha 2
This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading |
SAMD5 Genesterile alpha motif domain containing 5
Predicted to be involved in |
SAMD7 Genesterile alpha motif domain containing 7
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; chromatin binding activity; and histone binding activity. Predicted to be involved in negative |
SAMD1 Genesterile alpha motif domain containing 1
Enables chromatin binding activity. Involved in negative |
SAMD3 Genesterile alpha motif domain containing 3 |
SAMD8 Genesterile alpha motif domain containing 8
Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Involved in ceramide biosynthetic process and |
SAMD9 Genesterile alpha motif domain containing 9
This gene encodes a sterile alpha motif domain-containing protein. The encoded protein localizes to the cytoplasm and may play a role in regulating cell proliferation and apoptosis. Mutations in this gene are the cause |
CHRNA4 Genecholinergic receptor, nicotinic, alpha 4 (neuronal)
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily |
CHRNA5 Genecholinergic receptor, nicotinic, alpha 5 (neuronal)
The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member |
CHRNA6 Genecholinergic receptor, nicotinic, alpha 6 (neuronal)
This gene encodes an alpha subunit |
CHRNA7 Genecholinergic receptor, nicotinic, alpha 7 (neuronal)
The nicotinic acetylcholine receptors (nAChRs) are members |
CHRNA1 Genecholinergic receptor, nicotinic, alpha 1 (muscle)
The muscle acetylcholine receptor consiststs |
CHRNA2 Genecholinergic receptor, nicotinic, alpha 2 (neuronal)
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement |
CHRNA3 Genecholinergic receptor, nicotinic, alpha 3 (neuronal)
This locus encodes a member |
CHRNA9 Genecholinergic receptor, nicotinic, alpha 9 (neuronal)
This gene is a member |
SIRPA Genesignal-regulatory protein alpha
The protein encoded by this gene is a member |
IL3RA Geneinterleukin 3 receptor, alpha (low affinity)
The protein encoded by this gene is an interleukin 3 specific subunit |
ALG3P1 GeneALG3, alpha-1,3- mannosyltransferase pseudogene 1 |
DEFA11P Genedefensin, alpha 11 pseudogene |
LOC105376747 Genecollagen alpha-3(IX) chain-like |
FNTAP2 Genefarnesyltransferase, CAAX box, alpha pseudogene 2 |
PSMA2P3 Geneproteasome (prosome, macropain) subunit, alpha type, 2 pseudogene 3 |
PSMA2P1 Geneproteasome (prosome, macropain) subunit, alpha type, 2 pseudogene 1 |
LOC642890 GeneN(alpha)-acetyltransferase 50, NatE catalytic subunit pseudogene |
PCDHA10 Geneprotocadherin alpha 10
This gene is a member |
PCDHA11 Geneprotocadherin alpha 11
This gene is a member |
PCDHA12 Geneprotocadherin alpha 12
This gene is a member |
PCDHA13 Geneprotocadherin alpha 13
This gene is a member |
PCDHA14 Geneprotocadherin alpha 14 pseudogene |
LOC100884169 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 pseudogene |
COL1AR Genecollagen, type I, alpha, receptor |
COL1A2 Genecollagen, type I, alpha 2
This gene encodes the pro-alpha2 chain |
MEP1AP4 Genemeprin A, alpha pseudogene 4 |
MEP1AP3 Genemeprin A, alpha pseudogene 3 |
MEP1AP2 Genemeprin A, alpha pseudogene 2 |
MEP1AP1 Genemeprin A, alpha pseudogene 1 |
LOC101929990 Genecollagen alpha-1(XXVII) chain-like |
COL6A1 Genecollagen, type VI, alpha 1
The collagens are a superfamily |
COL6A2 Genecollagen, type VI, alpha 2
This gene encodes one |
COL6A5 Genecollagen, type VI, alpha 5
This gene encodes a member |
ANKS4B Geneankyrin repeat and sterile alpha motif domain containing 4B
Involved in brush border assembly; protein localization to microvillus; and protein-containing complex assembly. Located in brush border and microvillus. [provided by Alliance |
CHKA Genecholine kinase alpha
The major pathway for the biosynthesis |
LOC105377621 Genecollagen alpha-2(I) chain-like |
CAPZA3 Genecapping protein (actin filament) muscle Z-line, alpha 3
This gene encodes an actin capping protein, one |
CAPZA2 Genecapping protein (actin filament) muscle Z-line, alpha 2
The protein encoded by this gene is a member |
CAPZA1 Genecapping protein (actin filament) muscle Z-line, alpha 1
CAPZA1 is a member |
LOC105379509 Genefibril-forming collagen alpha chain-like |
LOC102724652 Genealpha-crystallin A chain |
COL17A1 Genecollagen, type XVII, alpha 1
This gene encodes the alpha chain |
LOC105373619 Genecollagen alpha-1(XI) chain-like |
IL1A Geneinterleukin 1, alpha
The protein encoded by this gene is a member |
KCNN4 Genepotassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
The protein encoded by this gene is part |
KCNN3 Genepotassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have pr |
KCNN2 Genepotassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have pr |
KCNN1 Genepotassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have pr |
PKIA Geneprotein kinase (cAMP-dependent, catalytic) inhibitor alpha
The protein encoded by this gene is a member |
SERPINA2 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene)
This gene encodes a member |
SERPINA3 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
The protein encoded by this gene is a member |
SERPINA4 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
Predicted to enable serine-type endopeptidase inhibitor activity. Located in extracellular exosome. Biomarker |
SERPINA5 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
The protein encoded by this gene is a member |
SERPINA6 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood |
SERPINA9 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
Enables serine-type endopeptidase inhibitor activity. Predicted to be located in cytoplasm; extracellular region; and membrane. Predicted to be active in extracellular space. [provided by Alliance |
LOC100129052 GeneN(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae) pseudogene |
PMPCAP1 Genepeptidase (mitochondrial processing) alpha pseudogene 1 |
PSMA2P2 Geneproteasome (prosome, macropain) subunit, alpha type, 2 pseudogene 2 |
ATRX Genealpha thalassemia/mental retardation syndrome X-linked
The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family |
GSTA12P Geneglutathione S-transferase alpha 12, pseudogene |
AMYP1 Geneamylase, alpha pseudogene 1 |
GSTA8P Geneglutathione S-transferase alpha 8, pseudogene |
LOC101059944 Genecollagen alpha-1(III) chain-like |
LOC646197 Geneheat shock protein 90kDa alpha (cytosolic), class B member 1 pseudogene |
SARM1 Genesterile alpha and TIR motif containing 1
Enables NAD+ nucleosidase activity; NAD+ nucleotidase, cyclic ADP-ribose generating; and identical protein binding activity. Involved in NAD catabolic process and response to axon injury. Is active in mitochondrion. [provided by Alliance |
SSR1 Genesignal sequence receptor, alpha
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists |
LOC105373316 Genecollagen alpha-4(IV) chain-like |
LOC441454 Geneprothymosin, alpha pseudogene |
GTF3C1 Genegeneral transcription factor IIIC, polypeptide 1, alpha 220kDa
Enables RNA polymerase III general transcription initiation factor activity. Predicted to be involved in 5S class rRNA transcription by RNA polymerase III and transcription initiation at RNA polymerase III promoter. Located in nucleolus and nucleoplasm. Part |
GTF3C6 Genegeneral transcription factor IIIC, polypeptide 6, alpha 35kDa
RNA polymerases are unable to initiate RNA synthesis in the absence |
LOC100422713 Geneprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 pseudogene |
LOC100422710 Geneprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 pseudogene |
FUCA1P1 Genefucosidase, alpha-L- 1, tissue pseudogene 1 |
SCN11A Genesodium channel, voltage gated, type XI alpha subunit
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed |
LOC100289303 Genetubulin, alpha 1b pseudogene |
LOC105370367 Genecollagen alpha-2(VIII) chain-like |
LOC105370368 Genecollagen alpha-2(I) chain-like |
IL20RA Geneinterleukin 20 receptor, alpha
This gene encodes a member |
INHA Geneinhibin, alpha
This gene encodes a member |
CAMK2A Genecalcium/calmodulin-dependent protein kinase II alpha
The product |
PRKAR1AP Geneprotein kinase, cAMP-dependent, regulatory, type I, alpha pseudogene |
LOC387720 Genecollagen alpha-1(X) chain |
RARA Generetinoic acid receptor, alpha
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in |
LOC105375661 Genecollagen alpha-1(I) chain-like |
LOC100421802 Geneprotein phosphatase 2, regulatory subunit B, alpha pseudogene |
NAA20 GeneN(alpha)-acetyltransferase 20, NatB catalytic subunit
NAT5 is a component |
NAA25 GeneN(alpha)-acetyltransferase 25, NatB auxiliary subunit
This gene encodes the auxiliary subunit |
LAPTM4A Genelysosomal protein transmembrane 4 alpha
This gene encodes a protein that has four predicted transmembrane domains. The function |
MAT2A Genemethionine adenosyltransferase II, alpha
The protein encoded by this gene catalyzes the production |
NAALADL2 GeneN-acetylated alpha-linked acidic dipeptidase-like 2
Predicted to act upstream |
NAALADL1 GeneN-acetylated alpha-linked acidic dipeptidase-like 1
Enables aminopeptidase activity; metal ion binding activity; and protein homodimerization activity. Involved in peptide catabolic process. Predicted to be located in apical plasma membrane. [provided by Alliance |
HADHAP2 Genehydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit pseudogene 2 |
ACTC1 Geneactin, alpha, cardiac muscle 1
Actins are highly conserved proteins that are involved in various types |
COL21A1 Genecollagen, type XXI, alpha 1
This gene encodes the alpha chain |
CACNA2D1 Genecalcium channel, voltage-dependent, alpha 2/delta subunit 1
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits |
GABPAP GeneGA binding protein transcription factor, alpha subunit pseudogene |
SNTA1 Genesyntrophin, alpha 1
Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components |
KCNMA1 Genepotassium channel, calcium activated large conductance subfamily M alpha, member 1
This gene encodes the alpha subunit |
FLNA Genefilamin A, alpha
The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause |
LOC642791 Geneeukaryotic translation elongation factor 1 alpha 2 pseudogene |
RABGGTA GeneRab geranylgeranyltransferase, alpha subunit
Predicted to enable small GTPase binding activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and protein geranylgeranylation. Predicted to be located in cytosol and plasma membrane. Predicted to be part |
PTAR1 Geneprotein prenyltransferase alpha subunit repeat containing 1
Predicted to enable protein prenyltransferase activity. Predicted to contribute to Rab geranylgeranyltransferase activity. Located in mitochondrion. [provided by Alliance |
GANC Geneglucosidase, alpha; neutral C
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member |
PI4KAP2 Genephosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
Predicted to enable kinase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. [provided by Alliance |
CEBPA GeneCCAAT/enhancer binding protein (C/EBP), alpha
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters |
LOC346329 Geneguanine nucleotide binding protein (G protein), alpha 11 (Gq class) pseudogene |
CTNNA1 Genecatenin (cadherin-associated protein), alpha 1, 102kDa
This gene encodes a member |
CTNNA2 Genecatenin (cadherin-associated protein), alpha 2
Enables actin filament binding activity. Involved in negative |
CTNNA3 Genecatenin (cadherin-associated protein), alpha 3 This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
MAN1A1 Genemannosidase, alpha, class 1A, member 1
This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis |
MAN1A2 Genemannosidase, alpha, class 1A, member 2
Alpha-mannosidases function at different stages |
MAN2A2 Genemannosidase, alpha, class 2A, member 2
Predicted to enable alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Predicted to be located in Golgi apparatus and membrane. Predicted to be active in Golgi membrane. [provided by Alliance |
MAN2A1 Genemannosidase, alpha, class 2A, member 1
This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog |
COL18A1 Genecollagen, type XVIII, alpha 1
This gene encodes the alpha chain |
TGFA Genetransforming growth factor, alpha
This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types |
AZGP1P1 Genealpha-2-glycoprotein 1, zinc-binding pseudogene 1 |
TUBA8 Genetubulin, alpha 8
This gene encodes a member |
LOC101929943 Genetropomyosin alpha-3 chain-like |
OXGR1 Geneoxoglutarate (alpha-ketoglutarate) receptor 1
This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out |
TUBAP Genetubulin, alpha pseudogene |
HIF3A Genehypoxia inducible factor 3, alpha subunit
The protein encoded by this gene is the alpha-3 subunit |
HIF1AP1 Genehypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) pseudogene 1 |
AP2A1 Geneadaptor-related protein complex 2, alpha 1 subunit
This gene encodes the alpha 1 adaptin subunit |
AP2A2 Geneadaptor-related protein complex 2, alpha 2 subunit
The protein encoded by this gene is a subunit |
CSF2RA Genecolony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
The protein encoded by this gene is the alpha subunit |
ATAT1 Genealpha tubulin acetyltransferase 1
This gene encodes a protein that localizes to clathrin-coated pits, where it acetylates alpha tubulin on lysine 40. This process may be important in microtubule growth, for instance during chemotaxis and the formation |
PRKACA Geneprotein kinase, cAMP-dependent, catalytic, alpha
This gene encodes one |
GNA14 Geneguanine nucleotide binding protein (G protein), alpha 14
This gene encodes a member |
GNA15 Geneguanine nucleotide binding protein (G protein), alpha 15 (Gq class)
Enables G protein-coupled receptor binding activity. Acts upstream |
GNA12 Geneguanine nucleotide binding protein (G protein) alpha 12
Enables G protein activity; protein phosphatase 2A binding activity; and protein phosphatase activator activity. Involved in |
GNA13 Geneguanine nucleotide binding protein (G protein), alpha 13
Enables G protein activity. Involved in G protein-coupled receptor signaling pathway. Located in cytosol and nucleus. [provided by Alliance |
GNA11 Geneguanine nucleotide binding protein (G protein), alpha 11 (Gq class)
The protein encoded by this gene belongs to the family |
OGDH Geneoxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
This gene encodes one subunit |
ALPK1 Genealpha-kinase 1
This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies |
ALPK3 Genealpha-kinase 3
Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in cardiac muscle cell development. Predicted to be active in nucleus. Implicated in familial hypertrophic cardiomyopathy. [provided by Alliance |
CSNK1A1 Genecasein kinase 1, alpha 1
Enables protein serine/threonine kinase activity. Involved in several processes, including peptidyl-serine phosphorylation; positive |
LOC100129001 Genegeneral transcription factor IIIC, polypeptide 6, alpha 35kDa pseudogene |
ATP5A1 GeneATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
This gene encodes a subunit |
SERPINA7P1 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 pseudogene 1 |
A3GALT2 Genealpha 1,3-galactosyltransferase 2
Predicted to enable N-acetyllactosaminide 3-alpha-galactosyltransferase activity and alpha-1,3-galactosyltransferase activity. Predicted to be involved in lipid glycosylation. Predicted to act upstream |
NACA2 Genenascent polypeptide-associated complex alpha subunit 2
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in nucleus. Predicted to be part |
NACAD GeneNAC alpha domain containing
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in nucleus. Predicted to be part |
PIANP GenePILR alpha associated neural protein
This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune |
GP1BA Geneglycoprotein Ib (platelet), alpha polypeptide
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed |
CSNK1A1P3 Genecasein kinase 1, alpha 1 pseudogene 3 |
CSNK1A1P2 Genecasein kinase 1, alpha 1 pseudogene 2 |
CSNK1A1P1 Genecasein kinase 1, alpha 1 pseudogene 1 |
COL28A1 Genecollagen, type XXVIII, alpha 1
COL28A1 belongs to a class |
DFFA GeneDNA fragmentation factor, 45kDa, alpha polypeptide
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation |
PITPNA Genephosphatidylinositol transfer protein, alpha
This gene encodes a member |
IL13RA2 Geneinterleukin 13 receptor, alpha 2
The protein encoded by this gene is closely related to Il13RA1, a subuint |
IL13RA1 Geneinterleukin 13 receptor, alpha 1
The protein encoded by this gene is a subunit |
MANEA Genemannosidase, endo-alpha
N-glycosylation |
LALBA Genelactalbumin, alpha-
This gene encodes alpha-lactalbumin, a principal protein |
EEF1A1P24 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 24 |
DOC2A Genedouble C2-like domains, alpha
There are at least two protein is |
LOC401677 Geneeukaryotic translation elongation factor 1 alpha 2 pseudogene |
EEF1A1P21 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 21 |
EEF1A1P29 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 29 |
COL11A1 Genecollagen, type XI, alpha 1
This gene encodes one |
COL11A2 Genecollagen, type XI, alpha 2
This gene encodes one |
CHRFAM7A GeneCHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
The nicotinic acetylcholine receptors (nAChRs) are members |
NDUFA11 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
This gene encodes a subunit |
NDUFA12 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
This gene encodes a protein which is part |
NDUFA13 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
This gene encodes a subunit |
CYBA Genecytochrome b-245, alpha polypeptide
Cytochrome b is comprised |
LOC105376684 Genecollagen alpha-2(I) chain-like |
HSPB9 Geneheat shock protein, alpha-crystallin-related, B9
Located in cytosol and nucleoplasm. [provided by Alliance |
NTF6A Geneneurotrophin 6 alpha (pseudogene) |
A2MP1 Genealpha-2-macroglobulin pseudogene 1 |
LOC100127917 Geneheat shock protein 90kDa alpha (cytosolic), class B member 1 pseudogene |
ALG9 GeneALG9, alpha-1,2-mannosyltransferase
This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder |
PSMA3 Geneproteasome (prosome, macropain) subunit, alpha type, 3
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed |
LOC105371935 Genecollagen alpha-4(IV) chain-like |
ACTR1A GeneARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
This gene encodes a 42.6 kD subunit |
PIP4K2A Genephosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers |
PDGFRA Geneplatelet-derived growth factor receptor, alpha polypeptide
This gene encodes a cell surface tyrosine kinase receptor for members |
LOC105372231 Genecollagen alpha-1(III) chain-like |
C4BPAP3 Genecomplement component 4 binding protein, alpha pseudogene 3 |
C4BPAP2 Genecomplement component 4 binding protein, alpha pseudogene 2 |
HSP90AA5P Geneheat shock protein 90kDa alpha (cytosolic), class A member 5, pseudogene
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and ATP-dependent protein folding chaperone. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. [provided by Alliance |
PTMAP8 Geneprothymosin, alpha pseudogene 8 |
HADHAP1 Genehydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit pseudogene 1 |
DEFA7P Genedefensin, alpha 7 pseudogene |
PCYT1A Genephosphate cytidylyltransferase 1, choline, alpha
This gene belongs to the cytidylyltransferase family and is involved in the |
SCN3A Genesodium channel, voltage gated, type III alpha subunit
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed |
PIK3C2A Genephosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic |
LOC100505788 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa pseudogene |
EEF1A1P13 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 13 |
EEF1A1P12 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 12 |
EEF1A1P11 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 11 |
EEF1A1P17 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 17 |
EEF1A1P16 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 16 |
FUT7 Genefucosyltransferase 7 (alpha (1,3) fucosyltransferase)
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation |
FUT6 Genefucosyltransferase 6 (alpha (1,3) fucosyltransferase)
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation |
FUT5 Genefucosyltransferase 5 (alpha (1,3) fucosyltransferase)
Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity and 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity. Involved in ceramide metabolic process; oligosaccharide metabolic process; and protein glycosylation. Predicted to be located in Golgi membrane. [provided by Alliance |
FUT4 Genefucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
The product |
FUT1 Genefucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
This gene encodes a Golgi stack membrane protein that is involved in the creation |
FUT9 Genefucosyltransferase 9 (alpha (1,3) fucosyltransferase)
The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis |
FUT8 Genefucosyltransferase 8 (alpha (1,6) fucosyltransferase)
This gene encodes an enzyme belonging to the family |
PEX11A Geneperoxisomal biogenesis factor 11 alpha
This gene is a member |
LOC100129456 Geneheat shock protein 90kDa alpha (cytosolic), class B member 1 pseudogene |
CBFA2T3 Genecore-binding factor, runt domain, alpha subunit 2; translocated to, 3
This gene encodes a member |
CBFA2T2 Genecore-binding factor, runt domain, alpha subunit 2; translocated to, 2
In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one |
GSTA7P Geneglutathione S-transferase alpha 7, pseudogene |
MAN2B2 Genemannosidase, alpha, class 2B, member 2
Predicted to enable alpha-mannosidase activity. Predicted to be involved in mannose metabolic process and oligosaccharide catabolic process. Located in extracellular exosome. [provided by Alliance |
MAN2B1 Genemannosidase, alpha, class 2B, member 1
This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism |
GSK3A Geneglycogen synthase kinase 3 alpha
This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control |
HSP90AB2P Geneheat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene
Predicted to enable ATP binding activity; ATP hydrolysis activity; and unfolded protein binding activity. Predicted to be involved in cellular response to heat; protein folding; and protein stabilization. Located in extracellular exosome. [provided by Alliance |
LOC105372487 Genetransformer-2 protein homolog alpha-like |
COL22A1 Genecollagen, type XXII, alpha 1
This gene encodes member |
LOC100129942 Genecapping protein (actin filament) muscle Z-line, alpha 2 pseudogene |
COL5A2 Genecollagen, type V, alpha 2
This gene encodes an alpha chain for one |
COL5A3 Genecollagen, type V, alpha 3
This gene encodes an alpha chain for one |
COL5A1 Genecollagen, type V, alpha 1
This gene encodes an alpha chain for one |
LOC100533710 Genemannosidase, alpha, class 1B, member 1 pseudogene |
CACNA2D2 Genecalcium channel, voltage-dependent, alpha 2/delta subunit 2
Calcium channels mediate the entry |
CACNA2D3 Genecalcium channel, voltage-dependent, alpha 2/delta subunit 3
This gene encodes a member |
CACNA2D4 Genecalcium channel, voltage-dependent, alpha 2/delta subunit 4
This gene encodes a member |
PIK3R1 Genephosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Phosphatidylinositol 3-kinase phosphorylates the inositol ring |
TUBAL3 Genetubulin, alpha-like 3
Predicted to enable GTP binding activity. Predicted to be a structural constituent |
SLC51A Genesolute carrier family 51, alpha subunit
Predicted to enable protein heterodimerization activity; protein homodimerization activity; and transmembrane transporter activity. Involved in bile acid secretion. Located in basolateral plasma membrane. Implicated in progressive familial intrahepatic cholestasis. [provided by Alliance |
CGA Geneglycoprotein hormones, alpha polypeptide
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting |
PDGFA Geneplatelet-derived growth factor alpha polypeptide
This gene encodes a member |
CSN1S2AP Genecasein alpha s2-like A, pseudogene
This locus is the equivalent |
PRKAR1A Geneprotein kinase, cAMP-dependent, regulatory, type I, alpha
cAMP is a signaling molecule important for a variety |
HLA-DMA Genemajor histocompatibility complex, class II, DM alpha
HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting |
IL10RA Geneinterleukin 10 receptor, alpha
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal |
C4BPA Genecomplement component 4 binding protein, alpha
This gene encodes a member |
LOC100422375 Genephosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha pseudogene |
PSMA2 Geneproteasome (prosome, macropain) subunit, alpha type, 2
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed |
PSMA1 Geneproteasome (prosome, macropain) subunit, alpha type, 1
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed |
PSMA7 Geneproteasome (prosome, macropain) subunit, alpha type, 7
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed |
PSMA4 Geneproteasome (prosome, macropain) subunit, alpha type, 4
This gene encodes a core alpha subunit |
PSMA5 Geneproteasome (prosome, macropain) subunit, alpha type, 5
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed |
PSMA8 Geneproteasome (prosome, macropain) subunit, alpha type, 8
Predicted to be involved in meiotic cell cycle and proteasome-mediated ubiquitin-dependent protein catabolic process. Located in extracellular exosome and nucleus. [provided by Alliance |
LOC100533848 GeneATPase, H+/K+ transporting, nongastric, alpha polypeptide pseudogene |
ADRA1A Geneadrenoceptor alpha 1A
Alpha-1-adrenergic receptors (alpha-1-ARs) are members |
ADRA1B Geneadrenoceptor alpha 1B
Alpha-1-adrenergic receptors (alpha-1-ARs) are members |
ADRA1D Geneadrenoceptor alpha 1D
Alpha-1-adrenergic receptors (alpha-1-ARs) are members |
LOC100506596 Genefibril-forming collagen alpha chain |
LOC105375938 Genecollagen alpha-1(I) chain-like |
GLRA1 Geneglycine receptor, alpha 1
The protein encoded by this gene is a subunit |
COL12A1 Genecollagen, type XII, alpha 1
This gene encodes the alpha chain |
COL6A4P1 Genecollagen, type VI, alpha 4 pseudogene 1
This transcribed pseudogene represents the 5' end |
LOC645680 Genekaryopherin alpha 2 pseudogene |
ALG10 GeneALG10, alpha-1,2-glucosyltransferase
This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function |
ALG11 GeneALG11, alpha-1,2-mannosyltransferase
This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side |
ALG12 GeneALG12, alpha-1,6-mannosyltransferase
This gene encodes a member |
AHSP Genealpha hemoglobin stabilizing protein This gene encodes a molecular chaperone which binds specifically to free alpha-globin and is involved in hemoglobin assembly. The encoded protein binds to monomeric alpha-globin until it has been transferred to beta-globin to form a heterodimer, which in turn binds to another heterodimer to form the stable tetrameric hemoglobin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
AHSG Genealpha-2-HS-glycoprotein
The protein encoded by this gene is a negatively-charged serum glycoprotein that is synthesized by hepatocytes. The encoded protein consists |
AMACR Genealpha-methylacyl-CoA racemase
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation |
LOC105371898 Geneprothymosin alpha-like |
LOC105376068 Genecollagen alpha-1(I) chain-like |
TUBA3FP Genetubulin, alpha 3f, pseudogene |
IFNA20P Geneinterferon, alpha 20, pseudogene |
COL6A4P2 Genecollagen, type VI, alpha 4 pseudogene 2
This transcribed pseudogene represents the 3' end |
NAGLU GeneN-acetylglucosaminidase, alpha
This gene encodes an enzyme that degrades heparan sulfate by hydrolysis |
LOC100422324 Genecapping protein (actin filament) muscle Z-line, alpha 1 pseudogene |
HSP90AA2P Geneheat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90AA2 is a cytosolic HSP90 protein. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]). See HSP90AA1 (MIM 140571) for further information on HSP90 proteins.[supplied by OMIM, Aug 2008] |
LOC645773 Genetubulin, alpha 4a pseudogene |
CTNNA1P1 Genecatenin (cadherin-associated protein), alpha 1 pseudogene 1 |
AFP Genealpha-fetoprotein
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is |
SSR1P1 Genesignal sequence receptor, alpha pseudogene 1 |
IFI27 Geneinterferon, alpha-inducible protein 27
Enables several functions, including RNA polymerase II-specific DNA-binding transcription factor binding activity; identical protein binding activity; and lamin binding activity. Involved in several processes, including defense response to symbiont; protein K48-linked ubiquitination; and pyroptotic inflammatory response. Acts upstream |
GNAI2P2 Geneguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 pseudogene 2 |
GNAI2P1 Geneguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 pseudogene 1 |
LOC100131280 Geneintegrin alpha FG-GAP repeat containing 2 pseudogene |
LOC105373140 Geneprothymosin alpha-like |
EIF2S1 Geneeukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
The translation initiation factor EIF2 catalyzes the first regulated step |
LOC102724035 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene |
EEF1A1P42 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 42 |
EEF1A1P43 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 43 |
LOC280665 Geneanti-CNG alpha 1 cation channel translation product-like |
COL25A1 Genecollagen, type XXV, alpha 1
This gene encodes a brain-specific membrane associated collagen. A product |
IGHA2 Geneimmunoglobulin heavy constant alpha 2 (A2m marker)
Contributes to immunoglobulin receptor binding activity. Involved in glomerular filtration and positive |
IGHA1 Geneimmunoglobulin heavy constant alpha 1
Contributes to immunoglobulin receptor binding activity. Involved in glomerular filtration and positive |
FARSA Genephenylalanyl-tRNA synthetase, alpha subunit
Aminoacyl-tRNA synthetases are a class |
IL23A Geneinterleukin 23, alpha subunit p19
This gene encodes a subunit |
LOC100653395 Genemethionine adenosyltransferase II, alpha pseudogene |
TOP2A Genetopoisomerase (DNA) II alpha 170kDa
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states |
SGCA Genesarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
This gene encodes a component |
DGKA Genediacylglycerol kinase, alpha 80kDa
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis |
TECTA Genetectorin alpha
The tectorial membrane is an extracellular matrix |
COL2A1 Genecollagen, type II, alpha 1
This gene encodes the alpha-1 chain |
LOC100421798 Geneeukaryotic translation elongation factor 1 alpha 2 pseudogene |
TTPAL Genetocopherol (alpha) transfer protein-like
Predicted to enable phosphatidylinositol bisphosphate binding activity. Located in membrane. [provided by Alliance |
NAA40 GeneN(alpha)-acetyltransferase 40, NatD catalytic subunit
Enables histone H2A acetyltransferase activity; histone H4 acetyltransferase activity; and peptide-serine-alpha-N-acetyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream |
HSP90AB7P Geneheat shock protein 90kDa alpha (cytosolic), class B member 7, pseudogene |
FUT11 Genefucosyltransferase 11 (alpha (1,3) fucosyltransferase)
Enables fucosyltransferase activity. Involved in N-glycan fucosylation. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Implicated in stomach cancer. Biomarker |
FUT10 Genefucosyltransferase 10 (alpha (1,3) fucosyltransferase)
Enables fucosyltransferase activity. Involved in N-glycan fucosylation. Located in Golgi apparatus; endoplasmic reticulum; and nucleoplasm. [provided by Alliance |
DEFA8P Genedefensin, alpha 8 pseudogene |
CHRNA10 Genecholinergic receptor, nicotinic, alpha 10 (neuronal)
Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Acts upstream |
CSN1S2BP Genecasein alpha s2-like B, pseudogene
This locus is found in a cluster |
RXRA Generetinoid X receptor, alpha
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects |
AZGP1P2 Genealpha-2-glycoprotein 1, zinc-binding pseudogene 2 |
SCN8A Genesodium channel, voltage gated, type VIII alpha subunit
This gene encodes a member |
LOC100422633 GeneALG11, alpha-1,2-mannosyltransferase pseudogene |
ITIH1 Geneinter-alpha-trypsin inhibitor heavy chain 1
This gene encodes a member |
ITIH3 Geneinter-alpha-trypsin inhibitor heavy chain 3
This gene encodes the heavy chain subunit |
ITIH2 Geneinter-alpha-trypsin inhibitor heavy chain 2
The inter-alpha-trypsin inhibitors (ITI) are a family |
ITIH5 Geneinter-alpha-trypsin inhibitor heavy chain family, member 5
This gene encodes a heavy chain component |
ITIH4 Geneinter-alpha-trypsin inhibitor heavy chain family, member 4
The protein encoded by this gene is secreted into the blood, where it is cleaved by plasma kallikrein into two smaller forms. Expression |
ITIH6 Geneinter-alpha-trypsin inhibitor heavy chain family, member 6
The protein encoded by this gene belongs to the interalpha trypsin inhibitor heavy chain (ITIH) family. Interalpha trypsin inhibitor (ITI) is composed |
IFNA6 Geneinterferon, alpha 6
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Biomarker |
CRYAA Genecrystallin, alpha A
Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed |
CAPZA1P Genecapping protein (actin filament) muscle Z-line, alpha 1 pseudogene |
CSNK2A3 Genecasein kinase 2, alpha 3 polypeptide
This gene encodes a protein that is highly similar to the casein kinase II alpha protein. Casein kinase II is a serine/threonine protein kinase complex that phosphorylates numerous substrates including casein. The alpha subunit is the catalytic component |
CSNK2A2 Genecasein kinase 2, alpha prime polypeptide
This gene encodes the alpha', or alpha 2, catalytic subunit |
CSNK2A1 Genecasein kinase 2, alpha 1 polypeptide
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed |
ATP1A4 GeneATPase, Na+/K+ transporting, alpha 4 polypeptide
The protein encoded by this gene belongs to the family |
ATP1A3 GeneATPase, Na+/K+ transporting, alpha 3 polypeptide
The protein encoded by this gene belongs to the family |
ATP1A2 GeneATPase, Na+/K+ transporting, alpha 2 polypeptide
The protein encoded by this gene belongs to the family |
ATP1A1 GeneATPase, Na+/K+ transporting, alpha 1 polypeptide
The protein encoded by this gene belongs to the family |
NAALAD2 GeneN-acetylated alpha-linked acidic dipeptidase 2
This gene is a member |
LOC100422287 Geneproteasome (prosome, macropain) subunit, alpha type, 3 pseudogene |
LOC100422286 Geneproteasome (prosome, macropain) subunit, alpha type, 1 pseudogene |
HLA-DPA1 Genemajor histocompatibility complex, class II, DP alpha 1
HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting |
HLA-DPA3 Genemajor histocompatibility complex, class II, DP alpha 3 (pseudogene) |
HLA-DPA2 Genemajor histocompatibility complex, class II, DP alpha 2 (pseudogene) |
PSMA3P Geneproteasome (prosome, macropain) subunit, alpha type, 3 pseudogene |
IL2RA Geneinterleukin 2 receptor, alpha
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance |
LOC101060022 Genenascent polypeptide-associated complex subunit alpha, muscle-specific form-like |
EEF1A1P34 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 34 |
EEF1A1P37 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 37 |
EEF1A1P32 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 32 |
PRKAA2 Geneprotein kinase, AMP-activated, alpha 2 catalytic subunit
The protein encoded by this gene is a catalytic subunit |
PRKAA1 Geneprotein kinase, AMP-activated, alpha 1 catalytic subunit
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit |
SAMD11P1 Genesterile alpha motif domain containing 11 pseudogene 1 |
LOC100129818 Genetubulin, alpha 1a pseudogene |
MANEAL Genemannosidase, endo-alpha-like
Predicted to enable alpha-mannosidase activity. Predicted to be located in Golgi membrane. [provided by Alliance |
GNAZ Geneguanine nucleotide binding protein (G protein), alpha z polypeptide
The protein encoded by this gene is a member |
GNAL Geneguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
LOC101929301 Genecollagen alpha-1(I) chain-like |
NAA11 GeneN(alpha)-acetyltransferase 11, NatA catalytic subunit
Enables peptide alpha-N-acetyltransferase activity. Involved in N-terminal protein amino acid acetylation. Located in several cellular components, including Golgi apparatus; centrosome; and nucleoplasm. Part |
IDUA Geneiduronidase, alpha-L-
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues |
NAPA GeneN-ethylmaleimide-sensitive factor attachment protein, alpha
This gene encodes a member |
COL15A1 Genecollagen, type XV, alpha 1
This gene encodes the alpha chain |
GJA1P1 Genegap junction protein, alpha 1, 43kDa pseudogene 1 |
LOC101928892 Genenascent polypeptide-associated complex subunit alpha, muscle-specific form-like |
LOC105377821 Genecollagen alpha-2(I) chain-like |
LOC100132857 Geneheat shock protein 90kDa alpha (cytosolic), class B member 1 pseudogene |
SERPINA13P Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13, pseudogene
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance |
IFI6 Geneinterferon, alpha-inducible protein 6
This gene was first identified as one |
LRSAM1 Geneleucine rich repeat and sterile alpha motif containing 1
This gene encodes a ring finger protein involved in a variety |
ENSA Geneendosulfine alpha
The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit |
GSTA11P Geneglutathione S-transferase alpha 11, pseudogene |
LOC105379421 Genecollagen alpha-1(III) chain-like |
GSTA9P Geneglutathione S-transferase alpha 9, pseudogene |
SGTA Genesmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
This gene encodes a protein which is capable |
ACTN4P1 Geneactinin, alpha 4 pseudogene 1 |
DTNA Genedystrobrevin, alpha
The protein encoded by this gene belongs to the dystrobrevin subfamily |
LOC101059958 Genecollagen alpha-1(II) chain-like |
LOC100419079 Genetubulin, alpha 1c pseudogene |
RALGAPA1P GeneRal GTPase activating protein, alpha subunit 1 (catalytic) pseudogene |
TNFAIP8 Genetumor necrosis factor, alpha-induced protein 8
Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in positive |
A1BG Genealpha-1-B glycoprotein
The protein encoded by this gene is a plasma glycoprotein |
TTPA Genetocopherol (alpha) transfer protein
This gene encodes a soluble protein that binds alpha-trocopherol, a form |
GABPA GeneGA binding protein transcription factor, alpha subunit 60kDa
This gene encodes one |
SERPINF1 Geneserpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
This gene encodes a member |
SERPINF2 Geneserpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
This gene encodes a member |
GADD45AP1 Genegrowth arrest and DNA-damage-inducible, alpha pseudogene 1 |
GANAB Geneglucosidase, alpha; neutral AB
This gene encodes the alpha subunit |
GLRA3 Geneglycine receptor, alpha 3
This gene encodes a member |
GLRA2 Geneglycine receptor, alpha 2
The glycine receptor consists |
GLRA4 Geneglycine receptor, alpha 4
This gene encodes a glycine receptor and member |
PPP2R3A Geneprotein phosphatase 2, regulatory subunit B'', alpha
This gene encodes one |
STRADA GeneSTE20-related kinase adaptor alpha
The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation |
TPM1 Genetropomyosin 1 (alpha)
This gene is a member |
ETFA Geneelectron-transfer-flavoprotein, alpha polypeptide
ETFA participates in catalyzing the initial step |
GNAO1 Geneguanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
The protein encoded by this gene represents the alpha subunit |
GMFA Geneglia maturation factor, alpha |
ENSAP3 Geneendosulfine alpha pseudogene 3 |
ENSAP2 Geneendosulfine alpha pseudogene 2 |
ENSAP1 Geneendosulfine alpha pseudogene 1 |
GNAT1 Geneguanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling |
GNAT3 Geneguanine nucleotide binding protein, alpha transducing 3
Sweet, bitter, and umami tastes are transmitted from taste receptors by a specific guanine nucleotide binding protein. The protein encoded by this gene is the alpha subunit |
GNAT2 Geneguanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling |
PDHA1P1 Genepyruvate dehydrogenase (lipoamide) alpha 1 pseudogene 1 |
CTNNAL1 Genecatenin (cadherin-associated protein), alpha-like 1
Predicted to enable actin filament binding activity and cadherin binding activity. Acts upstream |
LOC105379575 Genecollagen alpha-2(IV) chain-like |
ANKS3 Geneankyrin repeat and sterile alpha motif domain containing 3
Predicted to be located in cytoplasm. Predicted to be active in cilium. [provided by Alliance |
ANKS6 Geneankyrin repeat and sterile alpha motif domain containing 6
This gene encodes a protein containing multiple ankyrin repeats and a SAM domain. It is thought that this protein may localize to the proximal region |
INA Geneinternexin neuronal intermediate filament protein, alpha
Neur |
PHKA1P1 Genephosphorylase kinase, alpha 1 pseudogene 1 |
FCGRT Gene
Fc fragment
This gene encodes a receptor that binds the Fc region |
TRA2A Genetransformer 2 alpha homolog (Drosophila)
This gene is a member |
ATP5A1P4 GeneATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 4 |
ATP5A1P5 GeneATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 5 |
ATP5A1P7 GeneATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 7 |
ATP5A1P2 GeneATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 2 |
ATP5A1P3 GeneATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 3 |
ATP5A1P8 GeneATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 8 |
CXCL1 Genechemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
This antimicrobial gene encodes a member |
NAA16 GeneN(alpha)-acetyltransferase 16, NatA auxiliary subunit
Enables ribosome binding activity. Involved in N-terminal protein amino acid acetylation; negative |
NAA15 GeneN(alpha)-acetyltransferase 15, NatA auxiliary subunit
N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer |
NAA10 GeneN(alpha)-acetyltransferase 10, NatA catalytic subunit
N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer |
NDUFA6 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
This gene encodes a member |
NDUFA7 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
This gene encodes a subunit |
NDUFA5 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
This nuclear gene encodes a conserved protein that comprises the B13 subunit |
NDUFA2 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
The encoded protein is a subunit |
NDUFA3 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Part |
NDUFA1 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
The human NDUFA1 gene codes for an essential component |
NDUFA8 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
The protein encoded by this gene belongs to the complex I 19 kDa subunit family. Mammalian complex I is composed |
NDUFA9 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
The encoded protein is a subunit |
TNFAIP6 Genetumor necrosis factor, alpha-induced protein 6
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member |
TNFAIP1 Genetumor necrosis factor, alpha-induced protein 1 (endothelial)
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies |
TNFAIP3 Genetumor necrosis factor, alpha-induced protein 3 This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012] |
TNFAIP2 Genetumor necrosis factor, alpha-induced protein 2
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression |
ATP5A1P10 GeneATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1 pseudogene 10 |
COL26A1 Genecollagen, type XXVI, alpha 1
This gene encodes a protein containing an emilin domain and two collagen stretches. This gene may be associated with aspirin-intolerant asthma. Alternatively spliced transcript variants encoding different is |
LOC102724070 GeneNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 pseudogene |
HEXA Genehexosaminidase A (alpha polypeptide)
This gene encodes a member |
SCN5A Genesodium channel, voltage gated, type V alpha subunit
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke |
ALPK2 Genealpha-kinase 2
Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Involved in several processes, including epicardium morphogenesis; heart development; and negative |
IFNA12P Geneinterferon, alpha 12, pseudogene |
RALGAPA2 GeneRal GTPase activating protein, alpha subunit 2 (catalytic)
Predicted to enable GTPase activator activity and protein heterodimerization activity. Predicted to be involved in activation |
LOC100132812 Genenascent polypeptide-associated complex alpha subunit 2 pseudogene |
LOC105371095 Genecollagen alpha-3(IX) chain-like |
NAGA GeneN-acetylgalactosaminidase, alpha-
NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause |
MAN1A2P1 Genemannosidase, alpha, class 1A, member 2 pseudogene 1 |
MAN1B1 Genemannosidase, alpha, class 1B, member 1 This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011] |
GABRA5 Genegamma-aminobutyric acid (GABA) A receptor, alpha 5
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance |
GABRA4 Genegamma-aminobutyric acid (GABA) A receptor, alpha 4
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance |
GABRA6 Genegamma-aminobutyric acid (GABA) A receptor, alpha 6
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance |
GABRA1 Genegamma-aminobutyric acid (GABA) A receptor, alpha 1
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance |
GABRA3 Genegamma-aminobutyric acid (GABA) A receptor, alpha 3
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance |
GABRA2 Genegamma-aminobutyric acid (GABA) A receptor, alpha 2
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance |
HSP90AB4P Geneheat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene
Predicted to enable ATP binding activity; ATP hydrolysis activity; and unfolded protein binding activity. Predicted to be involved in cellular response to heat; protein folding; and protein stabilization. Predicted to be located in cytoplasm. Predicted to be part |
ADH1A Genealcohol dehydrogenase 1A (class I), alpha polypeptide
This gene encodes a member |
PSMA6P3 Geneproteasome (prosome, macropain) subunit, alpha type, 6 pseudogene 3 |
ESRRA Geneestrogen-related receptor alpha
The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members |
LOC100422294 Genecapping protein (actin filament) muscle Z-line, alpha 1 pseudogene |
LRG1 Geneleucine-rich alpha-2-glycoprotein 1
The leucine-rich repeat (LRR) family |
COL8A2 Genecollagen, type VIII, alpha 2
This gene encodes the alpha 2 chain |
COL8A1 Genecollagen, type VIII, alpha 1
This gene encodes one |
NDUFA5P5 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 5 |
NDUFA5P4 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 4 |
NDUFA5P6 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 6 |
NDUFA5P1 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 1 |
NDUFA5P3 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 3 |
DRAP1 Gene
DR1-associated protein 1 (negative c
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation |
COL16A1 Genecollagen, type XVI, alpha 1
This gene encodes the alpha chain |
CACNA1H Genecalcium channel, voltage-dependent, T type, alpha 1H subunit
This gene encodes a T-type member |
CACNA1I Genecalcium channel, voltage-dependent, T type, alpha 1I subunit
This gene encodes the pore-forming alpha subunit |
CACNA1A Genecalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Voltage-dependent calcium channels mediate the entry |
CACNA1B Genecalcium channel, voltage-dependent, N type, alpha 1B subunit
The protein encoded by this gene is the pore-forming subunit |
CACNA1C Genecalcium channel, voltage-dependent, L type, alpha 1C subunit
This gene encodes an alpha-1 subunit |
CACNA1D Genecalcium channel, voltage-dependent, L type, alpha 1D subunit
Voltage-dependent calcium channels mediate the entry |
CACNA1E Genecalcium channel, voltage-dependent, R type, alpha 1E subunit
Voltage-dependent calcium channels are multisubunit complexes consisting |
CACNA1F Genecalcium channel, voltage-dependent, L type, alpha 1F subunit
This gene encodes a multipass transmembrane protein that functions as an alpha-1 subunit |
LOC105373982 Genecollagen alpha-1(III) chain-like |
HIF1A Genehypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
This gene encodes the alpha subunit |
LOC100130704 Genecapping protein (actin filament) muscle Z-line, alpha 1 pseudogene |
RALGAPA1 GeneRal GTPase activating protein, alpha subunit 1 (catalytic)
This gene encodes a major subunit |
ACTN4P2 Geneactinin, alpha 4 pseudogene 2 |
HBA1 Genehemoglobin, alpha 1
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% |
HADHA Genehydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
This gene encodes the alpha subunit |
LOC645938 Genecapping protein (actin filament) muscle Z-line, alpha 1 pseudogene |
EDEM2 GeneER degradation enhancer, mannosidase alpha-like 2
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family |
EDEM3 GeneER degradation enhancer, mannosidase alpha-like 3
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation |
EDEM1 GeneER degradation enhancer, mannosidase alpha-like 1
Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity and misfolded protein binding activity. Involved in positive |
GJA10 Genegap junction protein, alpha 10, 62kDa
Connexins, such as GJA10, are involved in the formation |
HBAP1 Genehemoglobin, alpha pseudogene 1 |
P4HA2 Geneprolyl 4-hydroxylase, alpha polypeptide II
This gene encodes a component |
P4HA3 Geneprolyl 4-hydroxylase, alpha polypeptide III
This gene encodes a component |
P4HA1 Geneprolyl 4-hydroxylase, alpha polypeptide I
This gene encodes a component |
IL5RA Geneinterleukin 5 receptor, alpha
The protein encoded by this gene is an interleukin 5 specific subunit |
AZGP1 Genealpha-2-glycoprotein 1, zinc-binding
Predicted to enable RNA nuclease activity and protein transmembrane transporter activity. Involved in cell adhesion and detection |
LOC100421028 Genegap junction protein, alpha 4, 37kDa pseudogene |
SSR1P2 Genesignal sequence receptor, alpha pseudogene 2 |
EEF1A1P36 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 36 |
EEF1A1P30 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 30 |
LOC105379779 Genecollagen alpha-1(I) chain-like |
PPFIA2 Geneprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
The protein encoded by this gene is a member |
PPFIA3 Geneprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
The protein encoded by this gene is a member |
PPFIA1 Geneprotein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
The protein encoded by this gene is a member |
LOC100128362 Geneprotein phosphatase 2, catalytic subunit, alpha isozyme pseudogene |
IFNA22P Geneinterferon, alpha 22, pseudogene |
LOC100130620 Genetropomyosin 1 (alpha) pseudogene |
GAA Geneglucosidase, alpha; acid
This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation |
GFRA4 GeneGDNF family receptor alpha 4
The protein encoded by this gene is a member |
GFRA1 GeneGDNF family receptor alpha 1
This gene encodes a member |
GFRA3 GeneGDNF family receptor alpha 3
The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member |
GFRA2 GeneGDNF family receptor alpha 2
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control |
LOC728026 Geneprothymosin alpha-like |
LOC102725144 Genecollagen alpha-1(III) chain-like |
HSP90AA4P Geneheat shock protein 90kDa alpha (cytosolic), class A member 4, pseudogene
Predicted to enable ATP binding activity; ATP hydrolysis activity; and unfolded protein binding activity. Predicted to be involved in cellular response to heat; protein folding; and protein stabilization. Predicted to be located in cytoplasm. Predicted to be part |
PPARGC1A Geneperoxisome proliferator-activated receptor gamma, coactivator 1 alpha
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction |
IL22RA2 Geneinterleukin 22 receptor, alpha 2
This gene encodes a member |
IL22RA1 Geneinterleukin 22 receptor, alpha 1
The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists |
LOC100419901 Genecasein kinase 1, alpha 1 pseudogene |
LOC729856 Geneelongation factor 1-alpha-like |
PPARA Geneperoxisome proliferator-activated receptor alpha
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number |
FUCA1 Genefucosidase, alpha-L- 1, tissue
The protein encoded by this gene is a lysosomal enzyme involved in the degradation |
FUCA2 Genefucosidase, alpha-L- 2, plasma
This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% |
SERPINA12 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
Enables molecular function inhibitor activity. Predicted to act upstream |
SERPINA10 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity |
SERPINA11 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance |
SCN2A Genesodium channel, voltage gated, type II alpha subunit
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed |
NDUFA9P1 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, pseudogene 1 |
LOC642635 Genetubulin, alpha 4a pseudogene |
A4GALT Genealpha 1,4-galactosyltransferase
The protein encoded by this gene catalyzes the transfer |
EEF1A1P26 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 26 |
EEF1A1P25 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 25 |
EEF1A1P22 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 22 |
LOC101928841 Genecollagen alpha-1(II) chain-like |
EEF1A1P28 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 28 |
IFNA11P Geneinterferon, alpha 11, pseudogene |
PPP3R1 Geneprotein phosphatase 3, regulatory subunit B, alpha
Enables phosphatase binding activity and protein domain specific binding activity. Involved in calcineurin-NFAT signaling cascade and positive |
C4BPAP1 Genecomplement component 4 binding protein, alpha pseudogene 1 |
PTMAP4 Geneprothymosin, alpha pseudogene 4 |
PTMAP5 Geneprothymosin, alpha pseudogene 5 |
PTMAP6 Geneprothymosin, alpha pseudogene 6 |
PTMAP7 Geneprothymosin, alpha pseudogene 7 |
PTMAP1 Geneprothymosin, alpha pseudogene 1 |
PTMAP2 Geneprothymosin, alpha pseudogene 2 |
PTMAP3 Geneprothymosin, alpha pseudogene 3 |
NDUFA5P12 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 12 |
POLA2 Genepolymerase (DNA directed), alpha 2, accessory subunit
Predicted to enable DNA binding activity. Involved in DNA replication initiation and DNA replication, synthesis |
POLA1 Genepolymerase (DNA directed), alpha 1, catalytic subunit
This gene encodes the catalytic subunit |
HSP90AB3P Geneheat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene
Predicted to enable ATP binding activity; ATP hydrolysis activity; and unfolded protein binding activity. Predicted to be involved in cellular response to heat; protein folding; and protein stabilization. Located in extracellular exosome. [provided by Alliance |
LOC101927503 Genecollagen alpha-1(III) chain-like |
LOC105375304 Genecollagen alpha-1(I) chain-like |
LOC100422463 Genecalcium channel, voltage-dependent, L type, alpha 1C subunit pseudogene |
LOC100421842 Geneeukaryotic translation elongation factor 1 alpha 2 pseudogene |
LOC100421840 Geneeukaryotic translation elongation factor 1 alpha 2 pseudogene |
NAA60 GeneN(alpha)-acetyltransferase 60, NatF catalytic subunit
This gene encodes an enzyme that localizes to the Golgi apparatus, where it transfers an acetyl group to the N-terminus |
PDE6C Genephosphodiesterase 6C, cGMP-specific, cone, alpha prime
This gene encodes the alpha-prime subunit |
PDE6A Genephosphodiesterase 6A, cGMP-specific, rod, alpha
This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells |
IL11RA Geneinterleukin 11 receptor, alpha
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family |
LOC102724853 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene |
LOC441880 Geneeukaryotic translation elongation factor 1 alpha 2 pseudogene |
EEF1A1P40 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 40 |
EEF1A1P41 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 41 |
LOC644563 Genegeneral transcription factor IIIC, polypeptide 6, alpha 35kDa pseudogene |
COL20A1 Genecollagen, type XX, alpha 1
Predicted to be located in endoplasmic reticulum lumen and extracellular region. Predicted to be part |
PTMA Geneprothymosin, alpha
Enables DNA-binding transcription factor binding activity and histone binding activity. Involved in negative |
IFNA8 Geneinterferon, alpha 8
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to act upstream |
IFNA2 Geneinterferon, alpha 2
This gene is a member |
IFNA1 Geneinterferon, alpha 1
This gene is a member |
IFNA7 Geneinterferon, alpha 7
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance |
IFNA5 Geneinterferon, alpha 5
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance |
IFNA4 Geneinterferon, alpha 4
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance |
NDUFA5P9 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene 9 |
CRYAB Genecrystallin, alpha B
Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed |
NACAP1 Genenascent-polypeptide-associated complex alpha polypeptide pseudogene 1
Predicted to enable unfolded protein binding activity. Predicted to be involved in protein targeting to membrane. Predicted to be part |
NACAP3 Genenascent-polypeptide-associated complex alpha polypeptide pseudogene 3 |
NACAP2 Genenascent-polypeptide-associated complex alpha polypeptide pseudogene 2 |
NACAP5 Genenascent-polypeptide-associated complex alpha polypeptide pseudogene 5 |
NACAP4 Genenascent-polypeptide-associated complex alpha polypeptide pseudogene 4 |
NACAP7 Genenascent-polypeptide-associated complex alpha polypeptide pseudogene 7 |
NACAP6 Genenascent-polypeptide-associated complex alpha polypeptide pseudogene 6 |
COL7A1 Genecollagen, type VII, alpha 1
This gene encodes the alpha chain |
COL4A6 Genecollagen, type IV, alpha 6
This gene encodes one |
COL4A5 Genecollagen, type IV, alpha 5
This gene encodes one |
COL4A4 Genecollagen, type IV, alpha 4
This gene encodes one |
COL4A3 Genecollagen, type IV, alpha 3 (Goodpasture antigen)
Type IV collagen, the major structural component |
COL4A2 Genecollagen, type IV, alpha 2
This gene encodes one |
COL4A1 Genecollagen, type IV, alpha 1
This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components |
NDUFA4P1 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa, pseudogene 1 |
NDUFA4P2 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa, pseudogene 2 |
LOC105373289 Genecollagen alpha-1(III) chain-like |
GJA1 Genegap junction protein, alpha 1, 43kDa
This gene is a member |
GJA3 Genegap junction protein, alpha 3, 46kDa
The protein encoded by this gene is a connexin and is a component |
GJA4 Genegap junction protein, alpha 4, 37kDa
This gene encodes a member |
GJA5 Genegap junction protein, alpha 5, 40kDa
This gene is a member |
GJA8 Genegap junction protein, alpha 8, 50kDa
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation |
GJA9 Genegap junction protein, alpha 9, 59kDa
Connexins, such as GJA9, are involved in the formation |
EIF2B1 Geneeukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
This gene encodes one |
DEFA10P Genedefensin, alpha 10 pseudogene |
PSMA6 Geneproteasome (prosome, macropain) subunit, alpha type, 6
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed |
EIF2AK1 Geneeukaryotic translation initiation factor 2-alpha kinase 1
The protein encoded by this gene acts at the level |
EIF2AK3 Geneeukaryotic translation initiation factor 2-alpha kinase 3
The protein encoded by this gene phosphorylates the alpha subunit |
EIF2AK2 Geneeukaryotic translation initiation factor 2-alpha kinase 2
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form |
EIF2AK4 Geneeukaryotic translation initiation factor 2 alpha kinase 4
This gene encodes a member |
GJA6P Genegap junction protein, alpha 6, pseudogene |
COL19A1 Genecollagen, type XIX, alpha 1
This gene encodes the alpha chain |
HNF4A Genehepatocyte nuclear factor 4, alpha
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression |
LOC101929989 Genelipopolysaccharide-induced tumor necrosis factor-alpha factor-like
Predicted to enable zinc ion binding activity. Predicted to be involved in |
PMPCA Genepeptidase (mitochondrial processing) alpha
The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit |
NDUFA4L2 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
Located in mitochondrion. [provided by Alliance |
KAR GeneAromatic alpha-keto acid reductase |
MEP1A Genemeprin A, alpha (PABA peptide hydrolase)
Enables metallodipeptidase activity. Involved in epidermal growth factor receptor ligand maturation. Located in extracellular exosome. Part |
ARHGDIA GeneRho GDP dissociation inhibitor (GDI) alpha
This gene encodes a protein that plays a key role in the |
HBA2 Genehemoglobin, alpha 2
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% |
GBE1 Geneglucan (1,4-alpha-), branching enzyme 1
The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer |
FNTAP1 Genefarnesyltransferase, CAAX box, alpha pseudogene 1 |
DNMT3A GeneDNA (cytosine-5-)-methyltransferase 3 alpha CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016] |
REG3A Generegenerating islet-derived 3 alpha
This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression |
COL10A1 Genecollagen, type X, alpha 1
This gene encodes the alpha chain |
IL36A Geneinterleukin 36, alpha
The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression |
IFI27L1 Geneinterferon, alpha-inducible protein 27-like 1
Predicted to enable molecular adaptor activity. Involved in apoptotic process. Predicted to be located in membrane. Predicted to be active in mitochondrial membrane. [provided by Alliance |
IFI27L2 Geneinterferon, alpha-inducible protein 27-like 2
Predicted to enable molecular adaptor activity. Involved in apoptotic process. Located in mitochondrial membrane. [provided by Alliance |
TXLNA Genetaxilin alpha
Predicted to enable syntaxin binding activity. Predicted to be involved in exocytosis. Predicted to act upstream |
EEF1A1P27 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 27 |
EEF1A1P23 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 23 |
EEF1A1P20 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 20 |
PPP2R5A Geneprotein phosphatase 2, regulatory subunit B', alpha
The product |
PCDHA@ Geneprotocadherin alpha cluster, complex locus
The protocadherin alpha gene cluster is one |
PCDHA2 Geneprotocadherin alpha 2
This gene is a member |
PCDHA3 Geneprotocadherin alpha 3
This gene is a member |
PCDHA1 Geneprotocadherin alpha 1
This gene is a member |
PCDHA6 Geneprotocadherin alpha 6
This gene is a member |
PCDHA7 Geneprotocadherin alpha 7
This gene is a member |
PCDHA4 Geneprotocadherin alpha 4
This gene is a member |
PCDHA5 Geneprotocadherin alpha 5
This gene is a member |
IL15RA Geneinterleukin 15 receptor, alpha
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors |
PCDHA8 Geneprotocadherin alpha 8
This gene is a member |
PCDHA9 Geneprotocadherin alpha 9
This gene is a member |
TUBA3GP Genetubulin, alpha 3g, pseudogene |
GNAI2 Geneguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
The protein encoded by this gene is an alpha subunit |
GNAI3 Geneguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed |
GNAI1 Geneguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting |
MAP1LC3A Genemicrotubule-associated protein 1 light chain 3 alpha
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components |
CACNA1G Genecalcium channel, voltage-dependent, T type, alpha 1G subunit
Voltage-sensitive calcium channels mediate the entry |
AMY1C Geneamylase, alpha 1C (salivary)
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion |
TUBA3C Genetubulin, alpha 3c
Microtubules |
TUBA3E Genetubulin, alpha 3e
Microtubules |
TUBA3D Genetubulin, alpha 3d
This gene encodes a member |
NAGPA GeneN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation |
NFYAP1 Genenuclear transcription factor Y, alpha pseudogene 1 |
NDUFA10 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
The protein encoded by this gene is a component |
AMBP Genealpha-1-microglobulin/bikunin precursor
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily |
IDH3A Geneisocitrate dehydrogenase 3 (NAD+) alpha
Isocitrate dehydrogenases catalyze the oxidative decarboxylation |
ENO1P3 Geneenolase 1, (alpha) pseudogene 3 |
ENO1P2 Geneenolase 1, (alpha) pseudogene 2 |
ENO1P1 Geneenolase 1, (alpha) pseudogene 1 |
FNTA Genefarnesyltransferase, CAAX box, alpha
Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue |
PIK3CA Genephosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Phosphatidylinositol 3-kinase is composed |
COL11A2P1 Genecollagen, type XI, alpha 2 pseudogene 1 |
COL1A1 Genecollagen, type I, alpha 1
This gene encodes the pro-alpha1 chains |
SCN4A Genesodium channel, voltage gated, type IV alpha subunit
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed |
SCN10A Genesodium channel, voltage gated, type X alpha subunit
The protein encoded by this gene is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit. The properties |
ACTA1 Geneactin, alpha 1, skeletal muscle
The product encoded by this gene belongs to the actin family |
COL6A3 Genecollagen, type VI, alpha 3
This gene encodes the alpha-3 chain, one |
CALCA Genecalcitonin-related polypeptide alpha
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing |
COL6A6 Genecollagen, type VI, alpha 6
This gene encodes a large protein that contains multiple von Willebrand factor domains and forms a component |
CD79A GeneCD79a molecule, immunoglobulin-associated alpha
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function |
COL4A3BP Genecollagen, type IV, alpha 3 (Goodpasture antigen) binding protein
This gene encodes a kinase that specifically phosphorylates the N-terminal region |
HSP90AB1 Geneheat shock protein 90kDa alpha (cytosolic), class B member 1
This gene encodes a member |
ATP12A GeneATPase, H+/K+ transporting, nongastric, alpha polypeptide
The protein encoded by this gene belongs to the family |
ITFG3 Geneintegrin alpha FG-GAP repeat containing 3
Located in cell surface. [provided by Alliance |
ITFG2 Geneintegrin alpha FG-GAP repeat containing 2
Involved in cellular response to amino acid starvation; cellular response to glucose starvation; and negative |
ITFG1 Geneintegrin alpha FG-GAP repeat containing 1
Located in extracellular exosome. [provided by Alliance |
GLA Genegalactosidase, alpha
This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis |
CACNA1S Genecalcium channel, voltage-dependent, L type, alpha 1S subunit
This gene encodes one |
HLA-DRA Genemajor histocompatibility complex, class II, DR alpha
HLA-DRA is one |
GGTA2P Geneglycoprotein, alpha-galactosyltransferase 2, pseudogene |
PRKCA Geneprotein kinase C, alpha
Protein kinase C (PKC) is a family |
PHKA1 Genephosphorylase kinase, alpha 1 (muscle)
Phosphorylase kinase is a polymer |
PHKA2 Genephosphorylase kinase, alpha 2 (liver)
Phosphorylase kinase is a polymer |
LOC105379556 Genenascent polypeptide-associated complex subunit alpha, muscle-specific form-like |
LOC103091863 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene |
TOP3A Genetopoisomerase (DNA) III alpha
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states |
LOC442727 Geneprothymosin, alpha pseudogene |
PI4K2A Genephosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization |
LOC100422441 Geneheat shock protein 90kDa alpha (cytosolic), class B member 1 pseudogene |
IL27RA Geneinterleukin 27 receptor, alpha
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence |
COL23A1 Genecollagen, type XXIII, alpha 1
COL23A1 is a member |
PPP2R1A Geneprotein phosphatase 2, regulatory subunit A, alpha
This gene encodes a constant regulatory subunit |
NAA38 GeneN(alpha)-acetyltransferase 38, NatC auxiliary subunit
Predicted to enable RNA binding activity. Involved in negative |
NAA35 GeneN(alpha)-acetyltransferase 35, NatC auxiliary subunit
Predicted to enable transferase activity. Involved in negative |
NAA30 GeneN(alpha)-acetyltransferase 30, NatC catalytic subunit
Enables peptide alpha-N-acetyltransferase activity. Involved in protein stabilization. Located in cytosol and nucleus. Part |
HSPB6 Geneheat shock protein, alpha-crystallin-related, B6 This locus encodes a heat shock protein. The encoded protein likely plays a role in smooth muscle relaxation. [provided by RefSeq, Jan 2012] |
SNCA Gene
synuclein, alpha (non A4 component
Alpha-synuclein is a member |
MC1R Genemelanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types |
A2M Genealpha-2-macroglobulin
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum |
ENO1P4 Geneenolase 1, (alpha) pseudogene 4 |
FAP Genefibroblast activation protein, alpha
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts |
AMY2A Geneamylase, alpha 2A (pancreatic)
This gene encodes a member |
AMY2B Geneamylase, alpha 2B (pancreatic)
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion |
TUBAP2 Genetubulin, alpha pseudogene 2 |
TUBAP3 Genetubulin, alpha pseudogene 3 |
GUCY1A3 Geneguanylate cyclase 1, soluble, alpha 3
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion |
GUCY1A2 Geneguanylate cyclase 1, soluble, alpha 2
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion |
SCN7A Genesodium channel, voltage gated, type VII alpha subunit
This gene encodes one |
A2ML1 Genealpha-2-macroglobulin-like 1
This gene encodes a member |
LOC102723531 Genecollagen alpha-1(I) chain-like |
PSME1 Geneproteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed |
LOC100422337 Geneguanine nucleotide binding protein (G protein), alpha 13 pseudogene |
LOC391448 Genemannosidase, endo-alpha-like pseudogene |
PI4KAP1 Genephosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1 |
CPAMD8 GeneC3 and PZP-like, alpha-2-macroglobulin domain containing 8
This gene encodes a member |
HSP90AB6P Geneheat shock protein 90kDa alpha (cytosolic), class B member 6, pseudogene |
LOC100419045 Genetubulin, alpha 4a pseudogene |
LOC100419046 Genetubulin, alpha 4a pseudogene |
LOC102725000 Genecollagen alpha-2(V) chain-like |
LOC100287074 GeneARP1 actin-related protein 1 homolog A, centractin alpha (yeast) pseudogene |
BCKDHA Genebranched chain keto acid dehydrogenase E1, alpha polypeptide
The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism |
ALG10B GeneALG10B, alpha-1,2-glucosyltransferase
Enables dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity. Involved in dolichol-linked oligosaccharide biosynthetic process. Located in plasma membrane. Is active in endoplasmic reticulum membrane. Implicated in long QT syndrome 2. [provided by Alliance |
SERPINA15P Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 15, pseudogene |
NFKBIA Gene
nuclear factor
This gene encodes a member |
PPP1CA Geneprotein phosphatase 1, catalytic subunit, alpha isozyme
The protein encoded by this gene is one |
HIF1AN Genehypoxia inducible factor 1, alpha subunit inhibitor
Enables several functions, including 2-oxoglutarate-dependent dioxygenase activity; NF-kappaB binding activity; and transition metal ion binding activity. Involved in negative |
PPP2CA Geneprotein phosphatase 2, catalytic subunit, alpha isozyme
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one |
LOC645163 Genephosphatidylinositol 4-kinase type 2 alpha pseudogene |
LOC101928903 GeneN-alpha-acetyltransferase 20 pseudogene |
SAMD14 Genesterile alpha motif domain containing 14
Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization; calcium-mediated signaling; and neuron projection development. Predicted to be active in several cellular components, including actin cytoskeleton; dendrite; and postsynaptic density. [provided by Alliance |
SAMD15 Genesterile alpha motif domain containing 15
Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in signal transduction. [provided by Alliance |
SAMD12 Genesterile alpha motif domain containing 12
Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasmic side |
SAMD13 Genesterile alpha motif domain containing 13 |
SAMD10 Genesterile alpha motif domain containing 10
Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasmic side |
SAMD11 Genesterile alpha motif domain containing 11
Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; identical protein binding activity; and protein domain specific binding activity. Predicted to be involved in negative |
GTF2E1 Genegeneral transcription factor IIE, polypeptide 1, alpha 56kDa
Enables RNA polymerase II general transcription initiation factor activity. Involved in transcription by RNA polymerase II. Located in cytosol and nucleoplasm. Part |
LOC105376877 Genecollagen alpha-2(IV) chain-like |
COPA Genecoatomer protein complex, subunit alpha
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits |
LOC100420572 Geneglutathione S-transferase alpha 5 pseudogene |
LOC105379637 Genecollagen alpha-2(IV) chain-like |
LOC100286973 Geneprotein phosphatase 1, catalytic subunit, alpha isozyme pseudogene |
LTA Genelymphotoxin alpha
The encoded protein, a member |
EEF1A1P14 Geneeukaryotic translation elongation factor 1 alpha 1 pseudogene 14 |
GSTA10P Geneglutathione S-transferase alpha 10, pseudogene |
CDC42BPA GeneCDC42 binding protein kinase alpha (DMPK-like)
The protein encoded by this gene is a member |
CNGA1 Genecyclic nucleotide gated channel alpha 1
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization |
CNGA2 Genecyclic nucleotide gated channel alpha 2
The protein encoded by this gene represents the alpha subunit |
CNGA3 Genecyclic nucleotide gated channel alpha 3
This gene encodes a member |
CNGA4 Genecyclic nucleotide gated channel alpha 4
CNGA4 is a modulatory subunit |
LOC105374379 Genecollagen alpha-1(X) chain-like |
TUBA4A Genetubulin, alpha 4a
Microtubules |
TUBA4B Genetubulin, alpha 4b
Predicted to enable GTP binding activity. Predicted to be a structural constituent |
PCCA Genepropionyl CoA carboxylase, alpha polypeptide
The protein encoded by this gene is the alpha subunit |
LOC100420304 Genealpha-methylacyl-CoA racemase pseudogene |
COL13A1 Genecollagen, type XIII, alpha 1
This gene encodes the alpha chain |
LOC646745 Genegeneral transcription factor IIIC, polypeptide 6, alpha 35kDa pseudogene |
PILRA Genepaired immunoglobin-like type 2 receptor alpha
Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation |
LOC100421204 Genecyclic nucleotide gated channel alpha 1 pseudogene |
LOC105379510 Genecollagen alpha-1(II) chain-like |
WDSUB1 GeneWD repeat, sterile alpha motif and U-box domain containing 1
Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. [provided by Alliance |
LAMA1 Genelaminin, alpha 1
This gene encodes one |
LAMA2 Genelaminin, alpha 2
Laminin, an extracellular protein, is a major component |
LAMA3 Genelaminin, alpha 3
The protein encoded by this gene belongs to the laminin family |
LAMA4 Genelaminin, alpha 4
Laminins, a family |
LAMA5 Genelaminin, alpha 5
This gene encodes one |
ATP4A GeneATPase, H+/K+ exchanging, alpha polypeptide
The protein encoded by this gene belongs to a family |
LOC105371405 Genecollagen alpha-1(XIII) chain |
SAMD9L Genesterile alpha motif domain containing 9-like This gene encodes a cytoplasmic protein that acts as a tumor suppressor but also plays a key role in cell proliferation and the innate immune response to viral infection. The encoded protein contains an N-terminal sterile alpha motif domain. Naturally occurring mutations in this gene are associated with myeloid disorders such as juvenile myelomonocytic leukemia, acute myeloid leukemia, and myelodysplastic syndrome. Naturally occurring mutations are also associated with hepatitis-B related hepatocellular carcinoma, normophosphatemic familial tumoral calcinosis, and ataxia-pancytopenia syndrome. [provided by RefSeq, Apr 2017] |
CCHCR1 Genecoiled-coil alpha-helical rod protein 1
This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator |
NDUFA12P1 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 pseudogene 1 |
SERPINA1 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells |
SERPINA7 Geneserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members |
HSP90AA1 Geneheat shock protein 90kDa alpha (cytosolic), class A member 1
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding |
PSMA6P4 Geneproteasome (prosome, macropain) subunit, alpha type, 6 pseudogene 4 |
PSMA6P2 Geneproteasome (prosome, macropain) subunit, alpha type, 6 pseudogene 2 |
PSMA6P1 Geneproteasome (prosome, macropain) subunit, alpha type, 6 pseudogene 1 |
LOC102724773 GeneN-acetyllactosaminide alpha-1,3-galactosyltransferase-like |
LIFR Geneleukemia inhibitory factor receptor alpha
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action |
PPP2R2A Geneprotein phosphatase 2, regulatory subunit B, alpha
The product |
LOC101059906 Genecollagen alpha-2(IV) chain-like |
LOC100419036 Genetubulin, alpha 3e pseudogene |
LOC101928728 Genecollagen alpha-1(III) chain-like |
LOC101928722 Genenascent polypeptide-associated complex subunit alpha, muscle-specific form-like |
PAPOLA Genepoly(A) polymerase alpha
The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition |
GGTA1P Geneglycoprotein, alpha-galactosyltransferase 1 pseudogene
Alpha-1,3-galactosyltransferase (GGTA1) is an enzyme present in most mammals except man, apes, and Old World monkeys. This gene is thought to encode a truncated, non-enzymatic form |
LOC100533626 Genetubulin, alpha 1c pseudogene |
LOC100533627 Genetubulin, alpha 1c pseudogene |
LOC100507703 GeneHLA class I histocompatibility antigen, A-69 alpha chain-like |
LOC101928120 Genecollagen alpha-1(I) chain-like |
HSP90AA6P Geneheat shock protein 90kDa alpha (cytosolic), class A member 6, pseudogene |
COL3A1 Genecollagen, type III, alpha 1
This gene encodes the pro-alpha1 chains |
ADD1 Geneadducin 1 (alpha)
Adducins are a family |
AMY1A Geneamylase, alpha 1A (salivary)
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion |
AMY1B Geneamylase, alpha 1B (salivary)
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion |
SRD5A3P1 Genesteroid 5 alpha-reductase 3 pseudogene 1 |
GBGT1 Genegloboside alpha-1,3-N-acetylgalactosaminyltransferase 1
This gene encodes a glycosyltransferase that plays a role in the synthesis |
CSN1S1 Genecasein alpha s1
Predicted to be involved in several processes, including response to 11-deoxycorticosterone; response to dehydroepiandrosterone; and response to progesterone. Located in extracellular space. [provided by Alliance |
ACTA2 Geneactin, alpha 2, smooth muscle, aorta
This gene encodes one |
LOC102724866 GeneNADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 pseudogene |
MYH6 Genemyosin, heavy chain 6, cardiac muscle, alpha
Cardiac muscle myosin is a hexamer consisting |
PIP5K1A Genephosphatidylinositol-4-phosphate 5-kinase, type I, alpha
Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity and kinase binding activity. Involved in several processes, including activation |
COL24A1 Genecollagen, type XXIV, alpha 1
This gene is a member |
LOC105375110 Genecollagen alpha-1(III) chain-like |
LOC100132824 Genetubulin alpha-1C chain-like |
A4GNT Genealpha-1,4-N-acetylglucosaminyltransferase
This gene encodes a protein from the glycosyltransferase 32 family. The enzyme catalyzes the transfer |
LOC100130321 GeneDNA fragmentation factor, 45kDa, alpha polypeptide pseudogene |
GSTA6P Geneglutathione S-transferase alpha 6, pseudogene |
MAN1C1 Genemannosidase, alpha, class 1C, member 1
Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in ERAD pathway. Located in extracellular exosome. [provided by Alliance |
IFNA13 Geneinterferon, alpha 13
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance |
IFNA10 Geneinterferon, alpha 10
This gene encodes a protein that belongs to the type I interferon family |
IFNA17 Geneinterferon, alpha 17
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Implicated in Crimean-Congo hemorrhagic fever and sarcoidosis. [provided by Alliance |
IFNA16 Geneinterferon, alpha 16
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; positive |
IFNA14 Geneinterferon, alpha 14
Predicted to enable cytokine activity and type I interferon receptor binding activity. Predicted to be involved in several processes, including lymphocyte activation involved in immune response; response to exogenous dsRNA; and type I interferon-mediated signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance |
MAN2C1 Genemannosidase, alpha, class 2C, member 1
Predicted to enable alpha-mannosidase activity. Predicted to be involved in oligosaccharide catabolic process. Located in nucleoplasm. Implicated in congenital disorder |
PARVA Geneparvin, alpha
This gene encodes a member |
HSP90AB5P Geneheat shock protein 90kDa alpha (cytosolic), class B member 5, pseudogene |
SPTAN1 Genespectrin, alpha, non-erythrocytic 1
Spectrins are a family |
PI4KA Genephosphatidylinositol 4-kinase, catalytic, alpha
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis |
PSMA7P Geneproteasome (prosome, macropain) subunit, alpha type, 7 pseudogene |
SUCLG1 Genesuccinate-CoA ligase, alpha subunit
This gene encodes the alpha subunit |
LOC105371184 Genecollagen alpha-1(I) chain-like |
LOC100506248 Geneprothymosin alpha |
ATP5F1A GeneATP synthase F1 subunit alpha
This gene encodes a subunit |
ERO1A Geneendoplasmic reticulum oxidoreductase 1 alpha
Enables oxidoreductase activity. Involved in cell redox homeostasis and chaperone c |
SRPRA GeneSRP receptor subunit alpha
The gene encodes a subunit |
GGTA1 Geneglycoprotein alpha-galactosyltransferase 1 (inactive)
Alpha-1,3-galactosyltransferase (GGTA1) is an enzyme present in most mammals except man, apes, and Old World monkeys. This gene is thought to encode a truncated, non-enzymatic form |
NAA80 GeneN-alpha-acetyltransferase 80, NatH catalytic subunit
This gene encodes a member |
CSNKA2IP Genecasein kinase 2 subunit alpha' interacting protein
Predicted to be located in male germ cell nucleus. [provided by Alliance |
GUCY1A1 Geneguanylate cyclase 1 soluble subunit alpha 1
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion |
KPNA2P3 Genekaryopherin subunit alpha 2 pseudogene 3 |
ATP5F1AP3 GeneATP synthase F1 subunit alpha pseudogene 3 |
TUBAP12 Genetubulin alpha pseudogene 12 |
CSNK2A2IP Genecasein kinase 2 subunit alpha' interacting protein
Predicted to be located in male germ cell nucleus. [provided by Alliance |
LOC128966570 Genealpha-amylase 1B |
TIPE1 GeneTNF alpha induced protein 8 like 1
Enables identical protein binding activity. Predicted to be involved in negative |
TIPE3 GeneTNF alpha induced protein 8 like 3
Predicted to enable phosphatidylinositol binding activity and phosphatidylinositol transfer activity. Predicted to be involved in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process; phospholipid transport; and positive |
TIPE2 GeneTNF alpha induced protein 8 like 2
Predicted to be involved in negative |
LOC124903828 Genecollagen alpha-5(IV) chain-like |
LOC124905135 Genecollagen alpha-1(III) chain-like |
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4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose Gene Setinteracting proteins for the 4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose drug from the curated DrugBank Drug Targets dataset. |
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negative
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positive
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positive
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negative
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negative
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alpha thalassemia; alpha-thalassemia; anemia, sickle cell; glucosephosphate dehydrogenase deficiency; hemolysis; sickle cell anemia Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia; anemia, sickle cell; glucosephosphate dehydrogenase deficiency; hemolysis; sickle cell anemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
albuminuria; alpha thalassemia; alpha-thalassemia; anemia, sickle cell; sickle cell anemia Gene SetFrom GAD Gene-Disease Associations genes associated with the disease albuminuria; alpha thalassemia; alpha-thalassemia; anemia, sickle cell; sickle cell anemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha thalassemia; alpha-thalassemia; anemia, sickle cell; bone necrosis; osteonecrosis; sickle cell anemia Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia; anemia, sickle cell; bone necrosis; osteonecrosis; sickle cell anemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha thalassemia; alpha-thalassemia; anemia, sickle cell; sickle cell anemia Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia; anemia, sickle cell; sickle cell anemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
activation
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t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell Gene SetFrom GO Biological Process Annotations 2015 genes participating in the t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell biological process from the curated GO Biological Process Annotations 2015 dataset. |
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Gene SetFrom GO Biological Process Annotations 2023 genes participating in the T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell biological process from the curated GO Biological Process Annotations 2023 dataset. |
T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell Gene SetFrom GO Biological Process Annotations 2025 genes participating in the T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell biological process from the curated GO Biological Process Annotations 2025 dataset. |
cerebellar purkinje cell-granule cell precursor cell signaling involved in
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cerebellar Purkinje cell-granule cell precursor cell signaling involved in
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negative
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positive
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alpha,alpha-trehalose-phosphate synthase complex (udp-forming) Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores
proteins co-occuring with the alpha,alpha-trehalose-phosphate synthase complex (udp-forming) cellular component in abstracts |
SIRT1-HNF4-alpha-PGC-1-alpha complex, in response to fasting Gene Setproteins in the SIRT1-HNF4-alpha-PGC-1-alpha complex, in response to fasting protein complex from the CORUM Protein Complexes dataset. |
PCNA-MutS-alpha-MutL-alpha-DNA complex Gene Setproteins in the PCNA-MutS-alpha-MutL-alpha-DNA complex protein complex from the CORUM Protein Complexes dataset. |
IKK-alpha--ER-alpha-AIB1 complex Gene Setproteins in the IKK-alpha--ER-alpha-AIB1 complex protein complex from the CORUM Protein Complexes dataset. |
4,4'-(carbonylbis(imino-3,1-phenylenecarbonylimino-3,1-(4-methylphenylene)carbonylimino))bis(1,3-xylene-alpha,alpha'-diphosphonic acid) Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical 4,4'-(carbonylbis(imino-3,1-phenylenecarbonylimino-3,1-(4-methylphenylene)carbonylimino))bis(1,3-xylene-alpha,alpha'-diphosphonic acid) from the curated CTD Gene-Chemical Interactions dataset. |
2-(4-((dimethylamino)carbonyl)-3-fluorophenyl)-alpha,alpha-dimethyl-N-1,3,4-thiadiazol-2-yl-5H-(1)benzopyrano(2,3-b)pyridin-5-acetamide Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical 2-(4-((dimethylamino)carbonyl)-3-fluorophenyl)-alpha,alpha-dimethyl-N-1,3,4-thiadiazol-2-yl-5H-(1)benzopyrano(2,3-b)pyridin-5-acetamide from the curated CTD Gene-Chemical Interactions dataset. |
6,6'-bis(2,3-dimethoxybenzoyl)-alpha,alpha-trehalose Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical 6,6'-bis(2,3-dimethoxybenzoyl)-alpha,alpha-trehalose from the curated CTD Gene-Chemical Interactions dataset. |
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid from the curated CTD Gene-Chemical Interactions dataset. |
alpha,alpha-dimethoxytoluene Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical alpha,alpha-dimethoxytoluene from the curated CTD Gene-Chemical Interactions dataset. |
5-2-(4-((ethylmethylamino)carbonyl)-3-fluorophenyl)-alpha,alpha-dimethyl-N-1,3,4-thiadiazol-2-yl-5H-(1)benzopyrano(2,3-b)pyridin-5-acetamide Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical 5-2-(4-((ethylmethylamino)carbonyl)-3-fluorophenyl)-alpha,alpha-dimethyl-N-1,3,4-thiadiazol-2-yl-5H-(1)benzopyrano(2,3-b)pyridin-5-acetamide from the curated CTD Gene-Chemical Interactions dataset. |
Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside Gene Setinteracting proteins for the Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside drug from the curated DrugBank Drug Targets dataset. |
alpha thalassemia; alpha-thalassemia; anemia; malaria, cerebral; malaria, falciparum Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia; anemia; malaria, cerebral; malaria, falciparum in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha thalassemia; alpha-thalassemia; elliptocytosis, hereditary; malaria, falciparum Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia; elliptocytosis, hereditary; malaria, falciparum in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha thalassemia; alpha-thalassemia; hydrops fetalis Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia; hydrops fetalis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha thalassemia; alpha-thalassemia; fetal diseases Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia; fetal diseases in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha thalassemia; alpha-thalassemia Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha thalassemia; alpha-thalassemia; anemia, hypochromic Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha thalassemia; alpha-thalassemia; anemia, hypochromic in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha-n-acetylneuraminate alpha-2,8-sialyltransferase activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the alpha-n-acetylneuraminate alpha-2,8-sialyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
alpha,alpha-trehalase activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the alpha,alpha-trehalase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
alpha-n-acetylgalactosaminide alpha-2,6-sialyltransferase activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the alpha-n-acetylgalactosaminide alpha-2,6-sialyltransferase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
5α-pregnan-3α-ol-20-one Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors
receptors |
3 alpha,7 alpha,24-Trihydroxy-5beta-cholestanoyl-CoA Gene SetFrom HMDB Metabolites of Enzymes
interacting proteins for the 3 alpha,7 alpha,24-Trihydroxy-5beta-cholestanoyl-CoA metabolite from the curated HMDB Metabolites |
D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose Gene SetFrom HMDB Metabolites of Enzymes
interacting proteins for the D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose metabolite from the curated HMDB Metabolites |
4-alpha-Methyl-5-alpha-cholest-7-en-3-one Gene SetFrom HMDB Metabolites of Enzymes
interacting proteins for the 4-alpha-Methyl-5-alpha-cholest-7-en-3-one metabolite from the curated HMDB Metabolites |
3-alpha-hydroxy-5-alpha-androstane-17-one 3-D-glucuronide Gene SetFrom HMDB Metabolites of Enzymes
interacting proteins for the 3-alpha-hydroxy-5-alpha-androstane-17-one 3-D-glucuronide metabolite from the curated HMDB Metabolites |
17-alpha,20-alpha-Dihydroxypregn-4-en-3-one Gene SetFrom HMDB Metabolites of Enzymes
interacting proteins for the 17-alpha,20-alpha-Dihydroxypregn-4-en-3-one metabolite from the curated HMDB Metabolites |
3 alpha,7 alpha,26-Trihydroxy-5beta-cholestane Gene SetFrom HMDB Metabolites of Enzymes
interacting proteins for the 3 alpha,7 alpha,26-Trihydroxy-5beta-cholestane metabolite from the curated HMDB Metabolites |
Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
BRD-K20168484_1h-indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(1-methylethyl)- [cas]_A549_24.0_h_10.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K20168484_1h-indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(1-methylethyl)- [cas]_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K20168484_1h-indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(1-methylethyl)- [cas]_PC3_24.0_h_10.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K20168484_1h-indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(1-methylethyl)- [cas]_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway Gene SetFrom PANTHER Pathways proteins participating in the Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway pathway from the PANTHER Pathways dataset. |
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway Gene SetFrom PANTHER Pathways proteins participating in the Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway pathway from the PANTHER Pathways dataset. |
Alpha, Alpha-Trehalase Deficiency Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Alpha, Alpha-Trehalase Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
alpha,alpha-trehalase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the alpha,alpha-trehalase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
alpha,alpha-trehalase activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the alpha,alpha-trehalase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) Gene SetFrom COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
proteins co-occuring with the alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) cellular component in abstracts |
adenocarcinoma; carcinoma, large cell; carcinoma, small cell; carcinoma, squamous cell; lung neoplasms; neoplasm
|
Alpha cell (α cell)_Liver_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the Alpha cell (α cell)_Liver_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
Alpha cell (α cell)_Pancreatic islet_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the Alpha cell (α cell)_Pancreatic islet_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
Alpha cell (α cell)_Pancreas_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the Alpha cell (α cell)_Pancreas_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
Alpha cell (α cell)_Pancreas_Mouse Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the Alpha cell (α cell)_Pancreas_Mouse cell type from the CellMarker Gene-Cell Type Associations dataset. |
Alpha cell (α cell)_Pancreatic islet_Mouse Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the Alpha cell (α cell)_Pancreatic islet_Mouse cell type from the CellMarker Gene-Cell Type Associations dataset. |
negative
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negative
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negative
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positive
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positive
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positive
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negative
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negative
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negative
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positive
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negative
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positive
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negative
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positive
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negative
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positive
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positive
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positive
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negative
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negative
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negative
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positive
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negative
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positive
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positive
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negative
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negative
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eNOS activation and
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positive
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positive
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positive
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negative
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positive
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negative
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positive
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positive
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negative
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negative
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positive
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negative
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negative
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negative
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negative
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negative
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positive
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negative
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negative
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negative
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negative
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positive
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positive
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positive
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positive
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negative
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negative
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positive
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negative
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positive
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Metabolism
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positive
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positive
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positive
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negative
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positive
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negative
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negative
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negative
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positive
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negative
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negative
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negative
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negative
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negative
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negative
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positive
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negative
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negative
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negative
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positive
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positive
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positive
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positive
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positive
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negative
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positive
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negative
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negative
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the co-stimulatory signal during t-cell activation Gene SetFrom Biocarta Pathways proteins participating in the the co-stimulatory signal during t-cell activation pathway from the Biocarta Pathways dataset. |
activation
|
cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
nk t cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the nk t cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
myeloid cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the myeloid cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation-induced cell death
|
t cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the t cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
b cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the b cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
endothelial cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the endothelial cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
microglial cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the microglial cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
myeloid dendritic cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the myeloid dendritic cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
t cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the t cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
hepatic stellate cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the hepatic stellate cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
mast cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the mast cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
gamma-delta t cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the gamma-delta t cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
memory t cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the memory t cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
natural killer cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the natural killer cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
mast cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the mast cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
natural killer cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the natural killer cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
myeloid dendritic cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the myeloid dendritic cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
follicular dendritic cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the follicular dendritic cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
microglial cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the microglial cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
skeletal muscle satellite cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the skeletal muscle satellite cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
t-helper 2 cell activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the t-helper 2 cell activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
b cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the b cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
decreased t cell activation Gene SetFrom HPO Gene-Disease Associations genes associated with the decreased t cell activation phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset. |
defective b cell activation Gene SetFrom HPO Gene-Disease Associations genes associated with the defective b cell activation phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset. |
T-cell activation inhibitor, mitochondrial Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the T-cell activation inhibitor, mitochondrial protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
abnormal microglial cell activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal microglial cell activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal t cell activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal t cell activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
decreased activation-induced b cell apoptosis Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the decreased activation-induced b cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
decreased activation-induced cell death
|
abnormal b cell activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal b cell activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
increased activation-induced b cell apoptosis Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the increased activation-induced b cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal activation-induced b cell apoptosis Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal activation-induced b cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal activation-induced cell death
|
T cell activation Gene SetFrom PANTHER Pathways proteins participating in the T cell activation pathway from the PANTHER Pathways dataset. |
B cell activation Gene SetFrom PANTHER Pathways proteins participating in the B cell activation pathway from the PANTHER Pathways dataset. |
Transcriptional activation
|
Monoclonal Mast Cell Activation Syndrome Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Monoclonal Mast Cell Activation Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Decreased T Cell Activation Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype Decreased T Cell Activation in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
Defective B Cell Activation Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype Defective B Cell Activation in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
gamma-delta T cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the gamma-delta T cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
natural killer cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the natural killer cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
T cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the T cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
B cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the B cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
microglial cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the microglial cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
microglial cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the microglial cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
B cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the B cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
myeloid dendritic cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the myeloid dendritic cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
T-helper 1 cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the T-helper 1 cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
mast cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the mast cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
T cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the T cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
memory T cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the memory T cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
T-helper 2 cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the T-helper 2 cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation-induced cell death
|
myeloid dendritic cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the myeloid dendritic cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
natural killer cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the natural killer cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
endothelial cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the endothelial cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
mast cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the mast cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
myeloid cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the myeloid cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
NK T cell activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the NK T cell activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
abnormal T cell activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal T cell activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
decreased microglial cell activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased microglial cell activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal B cell activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal B cell activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
increased microglial cell activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the increased microglial cell activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
increased activation-induced B cell apoptosis Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the increased activation-induced B cell apoptosis phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
decreased activation-induced cell death
|
abnormal microglial cell activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal microglial cell activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
decreased activation-induced B cell apoptosis Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased activation-induced B cell apoptosis phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
Modulators
|
T cell activation SARS CoV 2 Gene SetFrom WikiPathways Pathways 2024 proteins participating in the T cell activation SARS CoV 2 pathway from the WikiPathways Pathways 2024 dataset. |
mRNA vaccine activation
|
Extrafollicular and follicular B cell activation by SARS CoV 2 Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Extrafollicular and follicular B cell activation by SARS CoV 2 pathway from the WikiPathways Pathways 2024 dataset. |
Transcriptional activation
|
natural killer cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the natural killer cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
T cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the T cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
B cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the B cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
NK T cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the NK T cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
activation-induced cell death
|
microglial cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2025 genes participating in the microglial cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset. |
microglial cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the microglial cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
B cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2025 genes participating in the B cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset. |
gamma-delta T cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the gamma-delta T cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
myeloid dendritic cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the myeloid dendritic cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
T-helper 1 cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the T-helper 1 cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
mast cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the mast cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
T cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2025 genes participating in the T cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset. |
memory T cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the memory T cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
T-helper 2 cell activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the T-helper 2 cell activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
myeloid dendritic cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2025 genes participating in the myeloid dendritic cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset. |
satellite cell activation involved in skeletal muscle regeneration Gene SetFrom GO Biological Process Annotations 2025 genes participating in the satellite cell activation involved in skeletal muscle regeneration biological process from the curated GO Biological Process Annotations 2025 dataset. |
natural killer cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2025 genes participating in the natural killer cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset. |
endothelial cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2025 genes participating in the endothelial cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset. |
mast cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2025 genes participating in the mast cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset. |
myeloid cell activation involved in immune response Gene SetFrom GO Biological Process Annotations 2025 genes participating in the myeloid cell activation involved in immune response biological process from the curated GO Biological Process Annotations 2025 dataset. |
negative
|
carcinoma, basal cell; carcinoma, squamous cell; neoplasms, second primary; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma Gene SetFrom GAD Gene-Disease Associations genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; neoplasms, second primary; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
carcinoma, basal cell; carcinoma, squamous cell; cocarcinogenesis; neoplasms, radiation-induced; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma; sunburn Gene SetFrom GAD Gene-Disease Associations genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; cocarcinogenesis; neoplasms, radiation-induced; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma; sunburn in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
carcinoma, basal cell; carcinoma, squamous cell; melanoma; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma Gene SetFrom GAD Gene-Disease Associations genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; melanoma; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
b-cell lymphomas; lymphoma, b-cell; lymphoma, large b-cell, diffuse; lymphoma, large-cell, diffuse Gene SetFrom GAD Gene-Disease Associations genes associated with the disease b-cell lymphomas; lymphoma, b-cell; lymphoma, large b-cell, diffuse; lymphoma, large-cell, diffuse in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
adenocarcinoma; carcinoma, large cell; carcinoma, non-small-cell lung; carcinoma, squamous cell; lung neoplasms; neoplasm
|
carcinoma, basal cell; carcinoma, squamous cell; dna damage; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma Gene SetFrom GAD Gene-Disease Associations genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; dna damage; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
carcinoma, basal cell; carcinoma, squamous cell; postoperative complications; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma Gene SetFrom GAD Gene-Disease Associations genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; postoperative complications; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
carcinoma, basal cell; carcinoma, squamous cell; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma Gene SetFrom GAD Gene-Disease Associations genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
adenocarcinoma; carcinoma, small cell; carcinoma, squamous cell; lung neoplasms; neoplasm
|
carcinoma, basal cell; carcinoma, squamous cell; melanoma; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma; sunburn Gene SetFrom GAD Gene-Disease Associations genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; melanoma; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma; sunburn in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
carcinoma, basal cell; carcinoma, squamous cell; melanoma; postoperative complications; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma Gene SetFrom GAD Gene-Disease Associations genes associated with the disease carcinoma, basal cell; carcinoma, squamous cell; melanoma; postoperative complications; skin basal cell carcinoma; skin neoplasms; squamous cell carcinoma in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
adenocarcinoma; carcinoma, giant cell; carcinoma, large cell; carcinoma, non-small-cell lung; carcinoma, squamous cell; lung neoplasms; neoplasm recurrence, local Gene SetFrom GAD Gene-Disease Associations genes associated with the disease adenocarcinoma; carcinoma, giant cell; carcinoma, large cell; carcinoma, non-small-cell lung; carcinoma, squamous cell; lung neoplasms; neoplasm recurrence, local in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
cell-cell signaling involved in cell-cell junction organization Gene SetFrom GO Biological Process Annotations 2015 genes participating in the cell-cell signaling involved in cell-cell junction organization biological process from the curated GO Biological Process Annotations 2015 dataset. |
non-small cell large cell lung carcinoma; non-small cell squamous cell lung carcinoma Gene SetFrom PhosphoSitePlus Phosphosite-Disease Associations proteins associated with the disease non-small cell large cell lung carcinoma; non-small cell squamous cell lung carcinoma from the curated PhosphoSitePlus Phosphosite-Disease Associations dataset. |
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positive
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positive
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negative
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|
|
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positive
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negative
|
negative
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positive
|
negative
|
|
positive
|
negative
|
|
positive
|
negative
|
Hypoxic and oxygen homeostasis
|
|
positive
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negative
|
negative
|
|
positive
|
negative
|
negative
|
negative
|
|
negative
|
|
positive
|
negative
|
positive
|
|
|
|
|
|
|
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positive
|
negative
|
negative
|
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positive
|
negative
|
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negative
|
negative
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positive
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|
|
alpha-thalassemia; anemia; glucosephosphate dehydrogenase deficiency; malaria, falciparum; sickle cell trait Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha-thalassemia; anemia; glucosephosphate dehydrogenase deficiency; malaria, falciparum; sickle cell trait in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha-thalassemia; anemia, sickle cell; glucosephosphate dehydrogenase deficiency; hemolysis; stroke Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha-thalassemia; anemia, sickle cell; glucosephosphate dehydrogenase deficiency; hemolysis; stroke in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha-thalassemia; anemia, sickle cell; cholelithiasis Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha-thalassemia; anemia, sickle cell; cholelithiasis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
alpha-thalassemia; glucosephosphate dehydrogenase deficiency; malaria, falciparum; sickle cell trait Gene SetFrom GAD Gene-Disease Associations genes associated with the disease alpha-thalassemia; glucosephosphate dehydrogenase deficiency; malaria, falciparum; sickle cell trait in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
Glial cell line-derived neurotrophic factor receptor alpha 2 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Glial cell line-derived neurotrophic factor receptor alpha 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Glial cell line-derived neurotrophic factor receptor, alpha 1/2 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Glial cell line-derived neurotrophic factor receptor, alpha 1/2 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Glial cell line-derived neurotrophic factor receptor, alpha 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Glial cell line-derived neurotrophic factor receptor, alpha 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Glial cell line-derived neurotrophic factor receptor, alpha 3 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Glial cell line-derived neurotrophic factor receptor, alpha 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
abnormal pancreatic alpha cell morphology Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal pancreatic alpha cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal t cell receptor alpha chain v-j recombination Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal t cell receptor alpha chain v-j recombination phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
increased pancreatic alpha cell number Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the increased pancreatic alpha cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal pancreatic alpha cell differentiation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal pancreatic alpha cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
decreased pancreatic alpha cell number Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the decreased pancreatic alpha cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal pancreatic alpha cell physiology Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal pancreatic alpha cell physiology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
alpha-tc1.9 cell Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores
proteins co-occuring with the tissue alpha-tc1.9 cell in abstracts |
alpha-tc1.6 cell Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores
proteins co-occuring with the tissue alpha-tc1.6 cell in abstracts |
pancreatic alpha cell line Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores
proteins co-occuring with the tissue pancreatic alpha cell line in abstracts |
pancreatic alpha cell Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores
proteins co-occuring with the tissue pancreatic alpha cell in abstracts |
Pancreas-pancreatic alpha cell Gene SetFrom Tabula Sapiens Gene-Cell Associations genes with high or low expression in Pancreas-pancreatic alpha cell relative to other cell types from the Tabula Sapiens Gene-Cell Associations dataset. |
decreased pancreatic alpha cell number Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased pancreatic alpha cell number phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
increased pancreatic alpha cell number Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the increased pancreatic alpha cell number phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal pancreatic alpha cell morphology Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal pancreatic alpha cell morphology phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
increased pancreatic alpha cell mass Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the increased pancreatic alpha cell mass phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal pancreatic alpha cell differentiation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal pancreatic alpha cell differentiation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
increased pancreatic alpha cell proliferation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the increased pancreatic alpha cell proliferation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal pancreatic alpha cell mass Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal pancreatic alpha cell mass phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
decreased pancreatic alpha cell mass Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the decreased pancreatic alpha cell mass phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal T cell receptor alpha chain V-J recombination Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal T cell receptor alpha chain V-J recombination phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
Human - Pancreas - L1 - alpha islet cell Gene SetFrom HuBMAP Azimuth Cell Type Annotations genes associated with the Human - Pancreas - L1 - alpha islet cell cell type from the HuBMAP Azimuth Cell Type Annotations dataset. |
Stem-cell-derived-alpha cell_Undefined_Human Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the Stem-cell-derived-alpha cell_Undefined_Human cell type from the CellMarker Gene-Cell Type Associations dataset. |
Pancreatic alpha cell Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025
proteins co-occuring with the tissue Pancreatic alpha cell in abstracts |
Pancreatic alpha cell line Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025
proteins co-occuring with the tissue Pancreatic alpha cell line in abstracts |
alpha-TC1.9 cell Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025
proteins co-occuring with the tissue alpha-TC1.9 cell in abstracts |
alpha-TC1.6 cell Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025
proteins co-occuring with the tissue alpha-TC1.6 cell in abstracts |
BWZ.36 CD8 alpha cell Gene SetFrom TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025
proteins co-occuring with the tissue BWZ.36 CD8 alpha cell in abstracts |
role
|
angiotensin ii mediated activation
|
role
|
ca-calmodulin-dependent protein kinase activation Gene SetFrom Biocarta Pathways proteins participating in the ca-calmodulin-dependent protein kinase activation pathway from the Biocarta Pathways dataset. |
transcriptional activation
|
activation
|
lck and fyn tyrosine kinases in initiation
|
aspirin blocks signaling pathway involved in platelet activation Gene SetFrom Biocarta Pathways proteins participating in the aspirin blocks signaling pathway involved in platelet activation pathway from the Biocarta Pathways dataset. |
intrinsic prothrombin activation pathway Gene SetFrom Biocarta Pathways proteins participating in the intrinsic prothrombin activation pathway pathway from the Biocarta Pathways dataset. |
extrinsic prothrombin activation pathway Gene SetFrom Biocarta Pathways proteins participating in the extrinsic prothrombin activation pathway pathway from the Biocarta Pathways dataset. |
activation
|
nfkb activation by nontypeable hemophilus influenzae Gene SetFrom Biocarta Pathways proteins participating in the nfkb activation by nontypeable hemophilus influenzae pathway from the Biocarta Pathways dataset. |
Macrophage Activation Syndrome Gene SetFrom CTD Gene-Disease Associations genes/proteins associated with the disease Macrophage Activation Syndrome from the curated CTD Gene-Disease Associations dataset. |
activation
|
reduced trans-activation impaired sperm production and male infertility Gene SetFrom GAD Gene-Disease Associations genes associated with the disease reduced trans-activation impaired sperm production and male infertility in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
activation
|
activation
|
integrin activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the integrin activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
complement activation, classical pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the complement activation, classical pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
neutrophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the neutrophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
astrocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the astrocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
activation
|
activation
|
activation
|
eosinophil activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the eosinophil activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
neutrophil activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the neutrophil activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
activation
|
activation
|
basophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the basophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
keratinocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the keratinocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
complement activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the complement activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
eosinophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the eosinophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
complement activation, lectin pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the complement activation, lectin pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
macrophage activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the macrophage activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
leukocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the leukocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
transcriptional activation by promoter-enhancer looping Gene SetFrom GO Biological Process Annotations 2015 genes participating in the transcriptional activation by promoter-enhancer looping biological process from the curated GO Biological Process Annotations 2015 dataset. |
carbon catabolite activation
|
leukocyte adhesive activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the leukocyte adhesive activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
monocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the monocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
factor xii activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the factor xii activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
amino acid activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the amino acid activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
plasminogen activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the plasminogen activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
complement activation, alternative pathway Gene SetFrom GO Biological Process Annotations 2015 genes participating in the complement activation, alternative pathway biological process from the curated GO Biological Process Annotations 2015 dataset. |
platelet activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the platelet activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
nitrogen catabolite activation
|
fibroblast activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the fibroblast activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
egg activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the egg activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
macrophage activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the macrophage activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
nitrogen catabolite activation
|
zymogen activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the zymogen activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
myeloid leukocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the myeloid leukocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
protein activation cascade Gene SetFrom GO Biological Process Annotations 2015 genes participating in the protein activation cascade biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
activation
|
trypsinogen activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the trypsinogen activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
granulocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the granulocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
lymphocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the lymphocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
basophil activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the basophil activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
activation
|
activation
|
carbon catabolite activation
|
lymphocyte activation Gene SetFrom GO Biological Process Annotations 2015 genes participating in the lymphocyte activation biological process from the curated GO Biological Process Annotations 2015 dataset. |
leukocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2015 genes participating in the leukocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2015 dataset. |
factor x activation deficiency Gene SetFrom HPO Gene-Disease Associations genes associated with the factor x activation deficiency phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset. |
Macrophage Activation Syndrome Gene SetFrom HuGE Navigator Gene-Phenotype Associations genes associated with the Macrophage Activation Syndrome phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset. |
sulfate activation for sulfonation Gene SetFrom HumanCyc Pathways proteins participating in the sulfate activation for sulfonation pathway from the HumanCyc Pathways dataset. |
fatty acid activation Gene SetFrom HumanCyc Pathways proteins participating in the fatty acid activation pathway from the HumanCyc Pathways dataset. |
Smad anchor for receptor activation, Smad-binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Smad anchor for receptor activation, Smad-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Vitamin B12-dependent methionine synthase, activation domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Vitamin B12-dependent methionine synthase, activation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Signal transducer and activation
|
Mediator complex, subunit Med25, PTOV activation and synapsin 2 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Mediator complex, subunit Med25, PTOV activation and synapsin 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
RFX1 transcription activation region Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the RFX1 transcription activation region protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Hox9, N-terminal activation domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Hox9, N-terminal activation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Rho GTPase activation protein Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Rho GTPase activation protein protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Cytoplasmic activation/proliferation-associated protein-1 C term Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Cytoplasmic activation/proliferation-associated protein-1 C term protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Nuclear respiratory factor-1, activation binding domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Nuclear respiratory factor-1, activation binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Linker-for-activation
|
Recombination-activation protein 1 Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Recombination-activation protein 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Caudal-like activation domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Caudal-like activation domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Signalling lymphocyte activation molecule family receptors Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Signalling lymphocyte activation molecule family receptors protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
Signal transducer and activation
|
Signaling lymphocytic activation molecule, N-terminal Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Signaling lymphocytic activation molecule, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMUGS_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMUGS_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_PC3_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_PC3_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_SKM1_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_SKM1_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_VCAP_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_VCAP_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_24.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_24.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMGI_6.0_h_6.0_um Gene SetFrom LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_RMGI_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures |
abnormal macrophage activation involved in immune response Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal macrophage activation involved in immune response phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal platelet activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal platelet activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal locomotor activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal locomotor activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
abnormal thymocyte activation Gene SetFrom MPO Gene-Phenotype Associations gene mutations causing the abnormal thymocyte activation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset. |
Hypoxia response via HIF activation Gene SetFrom PANTHER Pathways proteins participating in the Hypoxia response via HIF activation pathway from the PANTHER Pathways dataset. |
Validated targets
|
MAP kinase activation in TLR cascade Gene Setproteins participating in the MAP kinase activation in TLR cascade pathway from the Reactome Pathways dataset. |
Alternative complement activation Gene Setproteins participating in the Alternative complement activation pathway from the Reactome Pathways dataset. |
Activation
|
Activation
|
Activation
|
WNT mediated activation
|
GPVI-mediated activation cascade Gene Setproteins participating in the GPVI-mediated activation cascade pathway from the Reactome Pathways dataset. |
NGF-independant TRKA activation Gene Setproteins participating in the NGF-independant TRKA activation pathway from the Reactome Pathways dataset. |
FCERI mediated NF-kB activation Gene Setproteins participating in the FCERI mediated NF-kB activation pathway from the Reactome Pathways dataset. |
GABA A (rho) receptor activation Gene Setproteins participating in the GABA A (rho) receptor activation pathway from the Reactome Pathways dataset. |
Axonal growth inhibition (RHOA activation) Gene Setproteins participating in the Axonal growth inhibition (RHOA activation) pathway from the Reactome Pathways dataset. |
Activation
|
Nuclear Events (kinase and transcription factor activation) Gene Setproteins participating in the Nuclear Events (kinase and transcription factor activation) pathway from the Reactome Pathways dataset. |
Activation
|
Activation
|
ERK2 activation Gene Setproteins participating in the ERK2 activation pathway from the Reactome Pathways dataset. |
Activation
|
CREB phosphorylation through the activation
|
Activation
|
Activation
|
Activation
|
Activation
|
Post NMDA receptor activation events Gene Setproteins participating in the Post NMDA receptor activation events pathway from the Reactome Pathways dataset. |
ARMS-mediated activation Gene Setproteins participating in the ARMS-mediated activation pathway from the Reactome Pathways dataset. |
Activation
|
FCERI mediated MAPK activation Gene Setproteins participating in the FCERI mediated MAPK activation pathway from the Reactome Pathways dataset. |
Activation, myristolyation
|
Gamma carboxylation, hypusine formation and arylsulfatase activation Gene Setproteins participating in the Gamma carboxylation, hypusine formation and arylsulfatase activation pathway from the Reactome Pathways dataset. |
RIP-mediated NFkB activation via ZBP1 Gene Setproteins participating in the RIP-mediated NFkB activation via ZBP1 pathway from the Reactome Pathways dataset. |
GABA receptor activation Gene Setproteins participating in the GABA receptor activation pathway from the Reactome Pathways dataset. |
Transcriptional activation
|
Activation
|
Activation
|
Activation
|
Activation
|
TRAF6 mediated induction
|
TRAF6 mediated NF-kB activation Gene Setproteins participating in the TRAF6 mediated NF-kB activation pathway from the Reactome Pathways dataset. |
Activation
|
GP1b-IX-V activation signalling Gene Setproteins participating in the GP1b-IX-V activation signalling pathway from the Reactome Pathways dataset. |
Cam-PDE 1 activation Gene Setproteins participating in the Cam-PDE 1 activation pathway from the Reactome Pathways dataset. |
Activation
|
Activation
|
RSK activation Gene Setproteins participating in the RSK activation pathway from the Reactome Pathways dataset. |
Frs2-mediated activation Gene Setproteins participating in the Frs2-mediated activation pathway from the Reactome Pathways dataset. |
TRAF6 mediated IRF7 activation Gene Setproteins participating in the TRAF6 mediated IRF7 activation pathway from the Reactome Pathways dataset. |
Activation
|
Unblocking
|
Activation, translocation and oligomerization
|
FGFR3c ligand binding and activation Gene Setproteins participating in the FGFR3c ligand binding and activation pathway from the Reactome Pathways dataset. |
MEK activation Gene Setproteins participating in the MEK activation pathway from the Reactome Pathways dataset. |
Activation
|
Vitamins B6 activation to pyridoxal phosphate Gene Setproteins participating in the Vitamins B6 activation to pyridoxal phosphate pathway from the Reactome Pathways dataset. |
Activation
|
Ras activation uopn Ca2+ infux through NMDA receptor Gene Setproteins participating in the Ras activation uopn Ca2+ infux through NMDA receptor pathway from the Reactome Pathways dataset. |
CREB phosphorylation through the activation
|
PKA activation in glucagon signalling Gene Setproteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways dataset. |
Activation
|
Activation
|
The activation
|
TRAF3-dependent IRF activation pathway Gene Setproteins participating in the TRAF3-dependent IRF activation pathway pathway from the Reactome Pathways dataset. |
FGFR1c ligand binding and activation Gene Setproteins participating in the FGFR1c ligand binding and activation pathway from the Reactome Pathways dataset. |
Aflatoxin activation and detoxification Gene Setproteins participating in the Aflatoxin activation and detoxification pathway from the Reactome Pathways dataset. |
Processing and activation
|
FGFR1c and Klotho ligand binding and activation Gene Setproteins participating in the FGFR1c and Klotho ligand binding and activation pathway from the Reactome Pathways dataset. |
Activation
|
ERK activation Gene Setproteins participating in the ERK activation pathway from the Reactome Pathways dataset. |
Prolonged ERK activation events Gene Setproteins participating in the Prolonged ERK activation events pathway from the Reactome Pathways dataset. |
Transcriptional activation
|
activated TAK1 mediates p38 MAPK activation Gene Setproteins participating in the activated TAK1 mediates p38 MAPK activation pathway from the Reactome Pathways dataset. |
Activation
|
Activation
|
G-protein activation Gene Setproteins participating in the G-protein activation pathway from the Reactome Pathways dataset. |
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling Gene Setproteins participating in the TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling pathway from the Reactome Pathways dataset. |
SHC activation Gene Setproteins participating in the SHC activation pathway from the Reactome Pathways dataset. |
FGFR3 ligand binding and activation Gene Setproteins participating in the FGFR3 ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR3b ligand binding and activation Gene Setproteins participating in the FGFR3b ligand binding and activation pathway from the Reactome Pathways dataset. |
IRF3 mediated activation
|
Platelet activation, signaling and aggregation Gene Setproteins participating in the Platelet activation, signaling and aggregation pathway from the Reactome Pathways dataset. |
NOTCH2 Activation and Transmission
|
Activation and oligomerization
|
FGFR2 ligand binding and activation Gene Setproteins participating in the FGFR2 ligand binding and activation pathway from the Reactome Pathways dataset. |
PI3K/AKT activation Gene Setproteins participating in the PI3K/AKT activation pathway from the Reactome Pathways dataset. |
FGFR2c ligand binding and activation Gene Setproteins participating in the FGFR2c ligand binding and activation pathway from the Reactome Pathways dataset. |
CREB phosphorylation through the activation
|
Activation
|
Activation
|
GABA A receptor activation Gene Setproteins participating in the GABA A receptor activation pathway from the Reactome Pathways dataset. |
Caspase-8 activation by cleavage Gene Setproteins participating in the Caspase-8 activation by cleavage pathway from the Reactome Pathways dataset. |
Activation
|
PKA activation Gene Setproteins participating in the PKA activation pathway from the Reactome Pathways dataset. |
FGFR1b ligand binding and activation Gene Setproteins participating in the FGFR1b ligand binding and activation pathway from the Reactome Pathways dataset. |
Activation
|
TAK1 activates NFkB by phosphorylation and activation
|
TRKA activation by NGF Gene Setproteins participating in the TRKA activation by NGF pathway from the Reactome Pathways dataset. |
Lectin pathway
|
Glutamate Binding, Activation
|
Activation
|
FGFR2b ligand binding and activation Gene Setproteins participating in the FGFR2b ligand binding and activation pathway from the Reactome Pathways dataset. |
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Gene Setproteins participating in the NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 pathway from the Reactome Pathways dataset. |
Activation
|
HSF1 activation Gene Setproteins participating in the HSF1 activation pathway from the Reactome Pathways dataset. |
RAF activation Gene Setproteins participating in the RAF activation pathway from the Reactome Pathways dataset. |
IRAK2 mediated activation
|
Classical antibody-mediated complement activation Gene Setproteins participating in the Classical antibody-mediated complement activation pathway from the Reactome Pathways dataset. |
IRAK2 mediated activation
|
ERK1 activation Gene Setproteins participating in the ERK1 activation pathway from the Reactome Pathways dataset. |
eNOS activation Gene Setproteins participating in the eNOS activation pathway from the Reactome Pathways dataset. |
AMPK inhibits chREBP transcriptional activation activity Gene Setproteins participating in the AMPK inhibits chREBP transcriptional activation activity pathway from the Reactome Pathways dataset. |
FGFR4 ligand binding and activation Gene Setproteins participating in the FGFR4 ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR ligand binding and activation Gene Setproteins participating in the FGFR ligand binding and activation pathway from the Reactome Pathways dataset. |
FGFR1 ligand binding and activation Gene Setproteins participating in the FGFR1 ligand binding and activation pathway from the Reactome Pathways dataset. |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Gene Setproteins participating in the JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 pathway from the Reactome Pathways dataset. |
CREB phosphorylation through the activation
|
Activation
|
Activation
|
IRS activation Gene Setproteins participating in the IRS activation pathway from the Reactome Pathways dataset. |
FCGR activation Gene Setproteins participating in the FCGR activation pathway from the Reactome Pathways dataset. |
GABA B receptor activation Gene Setproteins participating in the GABA B receptor activation pathway from the Reactome Pathways dataset. |
Complement Activation, Classical Pathway(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Complement Activation, Classical Pathway(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
Transcriptional activation by NRF2(Homo sapiens) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Transcriptional activation by NRF2(Homo sapiens) pathway from the WikiPathways Pathways 2014 dataset. |
Complement Activation, Classical Pathway(Mus musculus) Gene SetFrom WikiPathways Pathways 2014 proteins participating in the Complement Activation, Classical Pathway(Mus musculus) pathway from the WikiPathways Pathways 2014 dataset. |
Nanoparticle-mediated activation
|
Macrophage Activation Syndrome Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Macrophage Activation Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Systemic Immune Activation Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Systemic Immune Activation in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
Activation
|
Factor X Activation Deficiency Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype Factor X Activation Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
activation
|
activation
|
complement activation, lectin pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the complement activation, lectin pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
macrophage activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the macrophage activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
|
activation
|
integrin activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the integrin activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
basophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the basophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
monocyte activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the monocyte activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
|
activation
|
activation
|
activation
|
activation
|
activation
|
monocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the monocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
macrophage activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the macrophage activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
|
activation
|
plasminogen activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the plasminogen activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
complement activation, classical pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the complement activation, classical pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
zymogen activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the zymogen activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
complement activation, alternative pathway Gene SetFrom GO Biological Process Annotations 2023 genes participating in the complement activation, alternative pathway biological process from the curated GO Biological Process Annotations 2023 dataset. |
Factor XII activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the Factor XII activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
astrocyte activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the astrocyte activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
|
activation
|
neutrophil activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the neutrophil activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
astrocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the astrocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
|
activation
|
activation
|
activation
|
neutrophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the neutrophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
|
transforming growth factor beta1 activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the transforming growth factor beta1 activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
activation
|
trypsinogen activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the trypsinogen activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
nitrogen catabolite activation
|
basophil activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the basophil activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
protein activation cascade Gene SetFrom GO Biological Process Annotations 2023 genes participating in the protein activation cascade biological process from the curated GO Biological Process Annotations 2023 dataset. |
lymphocyte activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the lymphocyte activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
granulocyte activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the granulocyte activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
eosinophil activation involved in immune response Gene SetFrom GO Biological Process Annotations 2023 genes participating in the eosinophil activation involved in immune response biological process from the curated GO Biological Process Annotations 2023 dataset. |
carbon catabolite activation
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amino acid activation Gene SetFrom GO Biological Process Annotations 2023 genes participating in the amino acid activation biological process from the curated GO Biological Process Annotations 2023 dataset. |
nitrogen catabolite activation
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abnormal egg activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal egg activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal locomotor activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal locomotor activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal platelet activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal platelet activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal thymocyte activation Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal thymocyte activation phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal macrophage activation involved in immune response Gene SetFrom MGI Mouse Phenotype Associations 2023 gene mutations causing the abnormal macrophage activation involved in immune response phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset. |
abnormal locomotor activation Gene SetFrom IMPC Knockout Mouse Phenotypes gene knockouts causing the abnormal locomotor activation phenotype in mic from the IMPC Knockout Mouse Phenotypes dataset. |
Human - Tonsil - L2 - GC-commited metabolic activation Gene SetFrom HuBMAP Azimuth Cell Type Annotations genes associated with the Human - Tonsil - L2 - GC-commited metabolic activation cell type from the HuBMAP Azimuth Cell Type Annotations dataset. |
Human - Tonsil - L2 - NBC first step activation Gene SetFrom HuBMAP Azimuth Cell Type Annotations genes associated with the Human - Tonsil - L2 - NBC first step activation cell type from the HuBMAP Azimuth Cell Type Annotations dataset. |
Human - Tonsil - L2 - NBC/OA first step activation Gene SetFrom HuBMAP Azimuth Cell Type Annotations genes associated with the Human - Tonsil - L2 - NBC/OA first step activation cell type from the HuBMAP Azimuth Cell Type Annotations dataset. |
calcium-dependent activation
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Activation myeloid cell_Brain_Mouse Gene SetFrom CellMarker Gene-Cell Type Associations genes associated with the Activation myeloid cell_Brain_Mouse cell type from the CellMarker Gene-Cell Type Associations dataset. |
Nanoparticle mediated activation
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Transcriptional activation by NRF2 in response to phytochemicals Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Transcriptional activation by NRF2 in response to phytochemicals pathway from the WikiPathways Pathways 2024 dataset. |
Interleukin 1 induced activation
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Nanomaterial induced inflammasome activation Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Nanomaterial induced inflammasome activation pathway from the WikiPathways Pathways 2024 dataset. |
Activation
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SARS CoV 2 B 1 1 7 variant antagonises innate immune activation Gene SetFrom WikiPathways Pathways 2024 proteins participating in the SARS CoV 2 B 1 1 7 variant antagonises innate immune activation pathway from the WikiPathways Pathways 2024 dataset. |
Vitamin K metabolism and activation
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Complement activation Gene SetFrom WikiPathways Pathways 2024 proteins participating in the Complement activation pathway from the WikiPathways Pathways 2024 dataset. |
AMPK inhibits chREBP transcriptional activation activity Gene Setproteins participating in the AMPK inhibits chREBP transcriptional activation activity pathway from the Reactome Pathways 2024 dataset. |
ARMS-mediated activation Gene Setproteins participating in the ARMS-mediated activation pathway from the Reactome Pathways 2024 dataset. |
AURKA Activation by TPX2 Gene Setproteins participating in the AURKA Activation by TPX2 pathway from the Reactome Pathways 2024 dataset. |
Activation and oligomerization
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation
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Activation, myristolyation
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Activation, translocation and oligomerization
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Aflatoxin activation and detoxification Gene Setproteins participating in the Aflatoxin activation and detoxification pathway from the Reactome Pathways 2024 dataset. |
Alternative complement activation Gene Setproteins participating in the Alternative complement activation pathway from the Reactome Pathways 2024 dataset. |
Axonal growth inhibition (RHOA activation) Gene Setproteins participating in the Axonal growth inhibition (RHOA activation) pathway from the Reactome Pathways 2024 dataset. |
CLEC7A (Dectin-1) induces NFAT activation Gene Setproteins participating in the CLEC7A (Dectin-1) induces NFAT activation pathway from the Reactome Pathways 2024 dataset. |
CREB1 phosphorylation through NMDA receptor-mediated activation
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CREB1 phosphorylation through the activation
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CREB1 phosphorylation through the activation
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Cam-PDE 1 activation Gene Setproteins participating in the Cam-PDE 1 activation pathway from the Reactome Pathways 2024 dataset. |
Caspase activation via Death Receptors in the presence
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Caspase activation via Dependence Receptors in the absence
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Caspase activation via extrinsic apoptotic signalling pathway Gene Setproteins participating in the Caspase activation via extrinsic apoptotic signalling pathway pathway from the Reactome Pathways 2024 dataset. |
Classical antibody-mediated complement activation Gene Setproteins participating in the Classical antibody-mediated complement activation pathway from the Reactome Pathways 2024 dataset. |
Defective F9 activation Gene Setproteins participating in the Defective F9 activation pathway from the Reactome Pathways 2024 dataset. |
Defects
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Drug-mediated inhibition
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FCERI mediated MAPK activation Gene Setproteins participating in the FCERI mediated MAPK activation pathway from the Reactome Pathways 2024 dataset. |
FCERI mediated NF-kB activation Gene Setproteins participating in the FCERI mediated NF-kB activation pathway from the Reactome Pathways 2024 dataset. |
FCGR activation Gene Setproteins participating in the FCGR activation pathway from the Reactome Pathways 2024 dataset. |
FGFR1 ligand binding and activation Gene Setproteins participating in the FGFR1 ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR1 mutant receptor activation Gene Setproteins participating in the FGFR1 mutant receptor activation pathway from the Reactome Pathways 2024 dataset. |
FGFR1b ligand binding and activation Gene Setproteins participating in the FGFR1b ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR1c and Klotho ligand binding and activation Gene Setproteins participating in the FGFR1c and Klotho ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR1c ligand binding and activation Gene Setproteins participating in the FGFR1c ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR2 ligand binding and activation Gene Setproteins participating in the FGFR2 ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR2 mutant receptor activation Gene Setproteins participating in the FGFR2 mutant receptor activation pathway from the Reactome Pathways 2024 dataset. |
FGFR2b ligand binding and activation Gene Setproteins participating in the FGFR2b ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR2c ligand binding and activation Gene Setproteins participating in the FGFR2c ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR3 ligand binding and activation Gene Setproteins participating in the FGFR3 ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR3 mutant receptor activation Gene Setproteins participating in the FGFR3 mutant receptor activation pathway from the Reactome Pathways 2024 dataset. |
FGFR3b ligand binding and activation Gene Setproteins participating in the FGFR3b ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR3c ligand binding and activation Gene Setproteins participating in the FGFR3c ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR4 ligand binding and activation Gene Setproteins participating in the FGFR4 ligand binding and activation pathway from the Reactome Pathways 2024 dataset. |
FGFR4 mutant receptor activation Gene Setproteins participating in the FGFR4 mutant receptor activation pathway from the Reactome Pathways 2024 dataset. |
Frs2-mediated activation Gene Setproteins participating in the Frs2-mediated activation pathway from the Reactome Pathways 2024 dataset. |
G-protein activation Gene Setproteins participating in the G-protein activation pathway from the Reactome Pathways 2024 dataset. |
GABA B receptor activation Gene Setproteins participating in the GABA B receptor activation pathway from the Reactome Pathways 2024 dataset. |
GABA receptor activation Gene Setproteins participating in the GABA receptor activation pathway from the Reactome Pathways 2024 dataset. |
GP1b-IX-V activation signalling Gene Setproteins participating in the GP1b-IX-V activation signalling pathway from the Reactome Pathways 2024 dataset. |
GPVI-mediated activation cascade Gene Setproteins participating in the GPVI-mediated activation cascade pathway from the Reactome Pathways 2024 dataset. |
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation Gene Setproteins participating in the Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation pathway from the Reactome Pathways 2024 dataset. |
Glutamate binding, activation
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HSF1 activation Gene Setproteins participating in the HSF1 activation pathway from the Reactome Pathways 2024 dataset. |
IRAK2 mediated activation
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IRAK2 mediated activation
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IRF3 mediated activation
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IRS activation Gene Setproteins participating in the IRS activation pathway from the Reactome Pathways 2024 dataset. |
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Gene Setproteins participating in the JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 pathway from the Reactome Pathways 2024 dataset. |
Lectin pathway
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MAP kinase activation Gene Setproteins participating in the MAP kinase activation pathway from the Reactome Pathways 2024 dataset. |
MAP2K and MAPK activation Gene Setproteins participating in the MAP2K and MAPK activation pathway from the Reactome Pathways 2024 dataset. |
MAP3K8 (TPL2)-dependent MAPK1/3 activation Gene Setproteins participating in the MAP3K8 (TPL2)-dependent MAPK1/3 activation pathway from the Reactome Pathways 2024 dataset. |
MAPK1 (ERK2) activation Gene Setproteins participating in the MAPK1 (ERK2) activation pathway from the Reactome Pathways 2024 dataset. |
MAPK3 (ERK1) activation Gene Setproteins participating in the MAPK3 (ERK1) activation pathway from the Reactome Pathways 2024 dataset. |
MET Receptor Activation Gene Setproteins participating in the MET Receptor Activation pathway from the Reactome Pathways 2024 dataset. |
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Gene Setproteins participating in the NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 pathway from the Reactome Pathways 2024 dataset. |
NGF-independant TRKA activation Gene Setproteins participating in the NGF-independant TRKA activation pathway from the Reactome Pathways 2024 dataset. |
NOTCH2 Activation and Transmission
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NOTCH3 Activation and Transmission
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NOTCH4 Activation and Transmission
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Noncanonical activation
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Nuclear Events (kinase and transcription factor activation) Gene Setproteins participating in the Nuclear Events (kinase and transcription factor activation) pathway from the Reactome Pathways 2024 dataset. |
PI3K/AKT activation Gene Setproteins participating in the PI3K/AKT activation pathway from the Reactome Pathways 2024 dataset. |
PKA activation Gene Setproteins participating in the PKA activation pathway from the Reactome Pathways 2024 dataset. |
PKA activation in glucagon signalling Gene Setproteins participating in the PKA activation in glucagon signalling pathway from the Reactome Pathways 2024 dataset. |
Paradoxical activation
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Platelet activation, signaling and aggregation Gene Setproteins participating in the Platelet activation, signaling and aggregation pathway from the Reactome Pathways 2024 dataset. |
Post NMDA receptor activation events Gene Setproteins participating in the Post NMDA receptor activation events pathway from the Reactome Pathways 2024 dataset. |
Processing and activation
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Prolonged ERK activation events Gene Setproteins participating in the Prolonged ERK activation events pathway from the Reactome Pathways 2024 dataset. |
RAF activation Gene Setproteins participating in the RAF activation pathway from the Reactome Pathways 2024 dataset. |
RAF-independent MAPK1/3 activation Gene Setproteins participating in the RAF-independent MAPK1/3 activation pathway from the Reactome Pathways 2024 dataset. |
RIP-mediated NFkB activation via ZBP1 Gene Setproteins participating in the RIP-mediated NFkB activation via ZBP1 pathway from the Reactome Pathways 2024 dataset. |
RSK activation Gene Setproteins participating in the RSK activation pathway from the Reactome Pathways 2024 dataset. |
Ras activation upon Ca2+ influx through NMDA receptor Gene Setproteins participating in the Ras activation upon Ca2+ influx through NMDA receptor pathway from the Reactome Pathways 2024 dataset. |
SLC15A4:TASL-dependent IRF5 activation Gene Setproteins participating in the SLC15A4:TASL-dependent IRF5 activation pathway from the Reactome Pathways 2024 dataset. |
STAT5 Activation Gene Setproteins participating in the STAT5 Activation pathway from the Reactome Pathways 2024 dataset. |
STAT5 activation downstream
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TAK1-dependent IKK and NF-kappa-B activation Gene Setproteins participating in the TAK1-dependent IKK and NF-kappa-B activation pathway from the Reactome Pathways 2024 dataset. |
TICAM1-dependent activation
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TRAF3-dependent IRF activation pathway Gene Setproteins participating in the TRAF3-dependent IRF activation pathway pathway from the Reactome Pathways 2024 dataset. |
TRAF6 mediated IRF7 activation Gene Setproteins participating in the TRAF6 mediated IRF7 activation pathway from the Reactome Pathways 2024 dataset. |
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling Gene Setproteins participating in the TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling pathway from the Reactome Pathways 2024 dataset. |
TRAF6 mediated NF-kB activation Gene Setproteins participating in the TRAF6 mediated NF-kB activation pathway from the Reactome Pathways 2024 dataset. |
TRAF6 mediated induction
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TRKA activation by NGF Gene Setproteins participating in the TRKA activation by NGF pathway from the Reactome Pathways 2024 dataset. |
The activation
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Transcriptional activation
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Transcriptional activation
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Unblocking
|
Vitamin B6 activation to pyridoxal phosphate Gene Setproteins participating in the Vitamin B6 activation to pyridoxal phosphate pathway from the Reactome Pathways 2024 dataset. |
WNT mediated activation
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Zygotic genome activation (ZGA) Gene Setproteins participating in the Zygotic genome activation (ZGA) pathway from the Reactome Pathways 2024 dataset. |
activated TAK1 mediates p38 MAPK activation Gene Setproteins participating in the activated TAK1 mediates p38 MAPK activation pathway from the Reactome Pathways 2024 dataset. |
eNOS activation Gene Setproteins participating in the eNOS activation pathway from the Reactome Pathways 2024 dataset. |
activation
|
activation
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complement activation, lectin pathway Gene SetFrom GO Biological Process Annotations 2025 genes participating in the complement activation, lectin pathway biological process from the curated GO Biological Process Annotations 2025 dataset. |
macrophage activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the macrophage activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
activation
|
zygotic genome activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the zygotic genome activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
integrin activation Gene SetFrom GO Biological Process Annotations 2025 genes participating in the integrin activation biological process from the curated GO Biological Process Annotations 2025 dataset. |
